LOCUS       DARYXZ010000001        68796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYXZ010000001 DARYXZ010000000
VERSION     DARYXZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TV186_000001"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TV186_000001"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1531449.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TV186_000002"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TV186_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1531450.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TV186_000003"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TV186_000003"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1531451.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TV186_000004"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TV186_000004"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL1531452.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TV186_000005"
     CDS             complement(6925..7623)
                     /locus_tag="TV186_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL1531453.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..9030)
                     /locus_tag="TV186_000006"
                     /pseudo
     CDS             complement(8009..9030)
                     /locus_tag="TV186_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(9565..11244)
                     /locus_tag="TV186_000007"
     CDS             complement(9565..11244)
                     /locus_tag="TV186_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531454.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(11419..16323)
                     /locus_tag="TV186_000008"
     CDS             complement(11419..16323)
                     /locus_tag="TV186_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1531455.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            16676..17503
                     /locus_tag="TV186_000009"
     CDS             16676..17503
                     /locus_tag="TV186_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL1531456.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(17579..17932)
                     /locus_tag="TV186_000010"
     CDS             complement(17579..17932)
                     /locus_tag="TV186_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL1531457.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(17936..18448)
                     /locus_tag="TV186_000011"
     CDS             complement(17936..18448)
                     /locus_tag="TV186_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL1531458.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(18905..19459)
                     /locus_tag="TV186_000012"
     CDS             complement(18905..19459)
                     /locus_tag="TV186_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1531459.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            19670..20299
                     /locus_tag="TV186_000013"
     CDS             19670..20299
                     /locus_tag="TV186_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL1531460.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            20758..21843
                     /locus_tag="TV186_000014"
     CDS             20758..21843
                     /locus_tag="TV186_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531461.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            22029..23240
                     /locus_tag="TV186_000015"
     CDS             22029..23240
                     /locus_tag="TV186_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1531462.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNRTLDIYISKDRNSKFQNLLGSTLVVKTPENKENCQCTKIYI
                     EENGKDGYYLYIYEDTNKNDKYDKNKDKLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQ
                     GPQGPRGDKGETGEKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPG
                     EKGDPGQQGIPGPKGDPGKDGEKGERGEQGPRGENPTPTPDPMPQPMPDPAPKPESKP
                     EPKPIPQPEVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVLGTGLLSLLG
                     LGFLTRRKRKQ"
     gene            23552..24643
                     /locus_tag="TV186_000016"
     CDS             23552..24643
                     /locus_tag="TV186_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1531463.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQSSGKGLPRTN
                     EAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(24776..25894)
                     /locus_tag="TV186_000017"
     CDS             complement(24776..25894)
                     /locus_tag="TV186_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531464.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(25891..27018)
                     /locus_tag="TV186_000018"
     CDS             complement(25891..27018)
                     /locus_tag="TV186_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531465.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(27027..27950)
                     /locus_tag="TV186_000019"
     CDS             complement(27027..27950)
                     /locus_tag="TV186_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1531466.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(27973..28659)
                     /locus_tag="TV186_000020"
     CDS             complement(27973..28659)
                     /locus_tag="TV186_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL1531467.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(28656..29327)
                     /locus_tag="TV186_000021"
     CDS             complement(28656..29327)
                     /locus_tag="TV186_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1531468.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(29302..30660)
                     /locus_tag="TV186_000022"
     CDS             complement(29302..30660)
                     /locus_tag="TV186_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL1531469.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(30673..31737)
                     /locus_tag="TV186_000023"
     CDS             complement(30673..31737)
                     /locus_tag="TV186_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL1531470.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(31734..32684)
                     /locus_tag="TV186_000024"
     CDS             complement(31734..32684)
                     /locus_tag="TV186_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL1531471.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(32912..33076)
                     /locus_tag="TV186_000025"
     CDS             complement(32912..33076)
                     /locus_tag="TV186_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL1531472.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
     gene            complement(33605..33862)
                     /locus_tag="TV186_000026"
     CDS             complement(33605..33862)
                     /locus_tag="TV186_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL1531473.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(34399..36438)
                     /locus_tag="TV186_000027"
     CDS             complement(34399..36438)
                     /locus_tag="TV186_000027"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL1531474.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(36804..37715)
                     /gene="glyQ"
                     /locus_tag="TV186_000028"
     CDS             complement(36804..37715)
                     /gene="glyQ"
                     /locus_tag="TV186_000028"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL1531475.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(38081..38614)
                     /locus_tag="TV186_000029"
     CDS             complement(38081..38614)
                     /locus_tag="TV186_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL1531476.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(38881..39105)
                     /locus_tag="TV186_000030"
                     /pseudo
     CDS             complement(38881..39105)
                     /locus_tag="TV186_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(39135..39974)
                     /locus_tag="TV186_000031"
     CDS             complement(39135..39974)
                     /locus_tag="TV186_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL1531477.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(40061..41209)
                     /gene="nagA"
                     /locus_tag="TV186_000032"
     CDS             complement(40061..41209)
                     /gene="nagA"
                     /locus_tag="TV186_000032"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL1531478.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(41326..42967)
                     /locus_tag="TV186_000033"
                     /pseudo
     CDS             complement(41326..42967)
                     /locus_tag="TV186_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            43158..43904
                     /locus_tag="TV186_000034"
     CDS             43158..43904
                     /locus_tag="TV186_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531479.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(44510..45352)
                     /locus_tag="TV186_000035"
     CDS             complement(44510..45352)
                     /locus_tag="TV186_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1531480.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            45484..46041
                     /locus_tag="TV186_000036"
     CDS             45484..46041
                     /locus_tag="TV186_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1531481.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(46452..47276)
                     /locus_tag="TV186_000037"
     CDS             complement(46452..47276)
                     /locus_tag="TV186_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1531482.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(47281..47895)
                     /locus_tag="TV186_000038"
     CDS             complement(47281..47895)
                     /locus_tag="TV186_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL1531483.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(48056..48928)
                     /locus_tag="TV186_000039"
     CDS             complement(48056..48928)
                     /locus_tag="TV186_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL1531484.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(49139..49624)
                     /locus_tag="TV186_000040"
                     /pseudo
     CDS             complement(49139..49624)
                     /locus_tag="TV186_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(49627..49893)
                     /locus_tag="TV186_000041"
                     /pseudo
     CDS             complement(49627..49893)
                     /locus_tag="TV186_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(49895..50827)
                     /locus_tag="TV186_000042"
     CDS             complement(49895..50827)
                     /locus_tag="TV186_000042"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL1531485.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(50837..51352)
                     /gene="lacB"
                     /locus_tag="TV186_000043"
     CDS             complement(50837..51352)
                     /gene="lacB"
                     /locus_tag="TV186_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL1531486.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(51368..51793)
                     /gene="lacA"
                     /locus_tag="TV186_000044"
     CDS             complement(51368..51793)
                     /gene="lacA"
                     /locus_tag="TV186_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL1531487.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            51929..52711
                     /locus_tag="TV186_000045"
     CDS             51929..52711
                     /locus_tag="TV186_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1531488.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(53127..53678)
                     /locus_tag="TV186_000046"
     CDS             complement(53127..53678)
                     /locus_tag="TV186_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1531489.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(53691..54641)
                     /locus_tag="TV186_000047"
     CDS             complement(53691..54641)
                     /locus_tag="TV186_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL1531490.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(55512..57743)
                     /locus_tag="TV186_000048"
     CDS             complement(55512..57743)
                     /locus_tag="TV186_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL1531491.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(57743..58177)
                     /locus_tag="TV186_000049"
     CDS             complement(57743..58177)
                     /locus_tag="TV186_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL1531492.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            58407..59444
                     /locus_tag="TV186_000050"
     CDS             58407..59444
                     /locus_tag="TV186_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1531493.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            complement(59516..59866)
                     /gene="rbfA"
                     /locus_tag="TV186_000051"
     CDS             complement(59516..59866)
                     /gene="rbfA"
                     /locus_tag="TV186_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL1531494.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(60056..62926)
                     /gene="infB"
                     /locus_tag="TV186_000052"
     CDS             complement(60056..62926)
                     /gene="infB"
                     /locus_tag="TV186_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL1531495.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            complement(62946..63248)
                     /locus_tag="TV186_000053"
     CDS             complement(62946..63248)
                     /locus_tag="TV186_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL1531496.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            complement(63241..63537)
                     /locus_tag="TV186_000054"
     CDS             complement(63241..63537)
                     /locus_tag="TV186_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL1531497.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            complement(63553..64707)
                     /gene="nusA"
                     /locus_tag="TV186_000055"
     CDS             complement(63553..64707)
                     /gene="nusA"
                     /locus_tag="TV186_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL1531498.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            complement(64817..65299)
                     /gene="rimP"
                     /locus_tag="TV186_000056"
     CDS             complement(64817..65299)
                     /gene="rimP"
                     /locus_tag="TV186_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL1531499.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
     gene            complement(66680..66859)
                     /locus_tag="TV186_000057"
     CDS             complement(66680..66859)
                     /locus_tag="TV186_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1531500.1"
                     /translation="MLTYDEFKQAIDRGYIVEDTVTIVRKNGQIFDYVLPHEKVKNGE
                     VVTDEKVEEVLMELE"
     gene            complement(66926..67720)
                     /locus_tag="TV186_000058"
     CDS             complement(66926..67720)
                     /locus_tag="TV186_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1531501.1"
                     /translation="MNNIRLRKFISSIFLILLISSPISLSYQQATLADTKEVNVANSY
                     NSSDTYLPEALSWTLETSPNYYKVLGESGIVENLFPPKGQIVYGGLDSLGRTLTVRGT
                     LTFNNVLGSYNIRKDFKRSKAETLSGWLGNKNGEVYVIKGLGDDSYQGYFWNKSHLIA
                     DSLGGDALRVNAITGTRTQNVGGRSGNGGMRYTEIKSQKWLEAHRDGYLYYEAMPIYQ
                     GNELVPRAVVVSVLSSDNTINEKVIVYNVANGYTIDYNQGTFSANQ"
     gene            complement(67948..>68796)
                     /locus_tag="TV186_000059"
     CDS             complement(67948..>68796)
                     /locus_tag="TV186_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1531502.1"
                     /translation="IKAAGYATASGYAELLIQIIEENDLQKWDEEALKTNKEVTMTTA
                     NEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLWGNAIDLLNSASAQG
                     LEIIYNAPGVNPRAGDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHTKQTVDTAPQTSDTIVETPKTGTFTVDVAEINIR
                     RWPSLASEVVGSYKQDDTVSFDSEGYANGYYWISYVGDSGKRNYLAIGQTDKDGNRIS
                     LWGKLN"
BASE COUNT        20100 a        16291 c        13210 g        19195 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatttctt tttttgccat ttttattccc ctttaaatat aatggacata
     9061 atgtctccta attatcaatg acagataatt acacttttat tataaaaggt attttctgtt
     9121 tagtcaagag aaaactgttt cttttacatt tctgttattt tacagttata tgtcacatct
     9181 gatttggttt aatttttctg aaaaaccagt agataaggca ttttaagcat tttttgatga
     9241 taagataata tcacaaaaca ttaattatat gacaattatt gtttttaatt attagaattt
     9301 ttaatcaaaa ctatcctgca atcagctgtt tagccatttt aaaaggcaaa caaaaaccat
     9361 gccacattgc aatgacatgg ttttcttcaa gaaaggagcg agctttggtt tggtactttc
     9421 tacaactgat ctccaatagc agctgctcct cgttagtccc tgagccacag gtgactgagc
     9481 tttcctgcgg ctactctgat agtaccagct actcttacaa ctgcataaag cagtggctgc
     9541 cagccaagct aaagctaaac aatattactc tgttatagct tggtctgctg acgagctctc
     9601 aatggtcatg tgattgaggt agttgtcatc agccagctga gccttaaact ggtctccgac
     9661 ctttaggaaa ggcagacggt cactagtttc actgcttgcc ttgattttat aaatctgacc
     9721 cttggaggaa atgtaataaa ccgttgttcc tgagataatc tggctggcca attgctccac
     9781 ctgcccagta atcatcttga ccttctgatc attggtgtct gacactgaca gcgagcttgt
     9841 gtccttatct gtgaattgtg agattaaggt ctgaatgtca ttattcactg ttacctgctg
     9901 ataatcctct gcatcaacca aggcatagga ttttatcaga ccagccccgt ccttcaatga
     9961 gataaggtaa taagccttgt catttaactt gactagggtt ggtgcagttg cagtgtattt
    10021 cttctcttga acttcgccct cggctgattt catggcagag gcctctgttg cagaaggcag
    10081 cttatagtta gtgacctctc tggtacgcat gttaaccaaa ataaagccga gatttgacga
    10141 atcagctgtt gctgaggtga ttcctgtata gaggtaaatg tctgagccga tggtaatgta
    10201 gttatagctg tctgttgttt gcttgacatc tgtctggcta aagacagtgt tccaatagcc
    10261 cttttgatag gtgtaatagt cattaaccct ctccaaaaca ttgtcagcag aatagacacg
    10321 atcaacccat tttggaacgt cctttagctc atagtattga gacttgccgc taaccgcgtc
    10381 taacaggatc acacccgtcg gctcctgaga ggacaggcca aattttgggg cgtaggttgt
    10441 tgcgacatag taagggttac catcgtcatc aacctcaaat gacgggtctg aaaaaatggt
    10501 catcgggtac tggaagcgca aatgcctcat ggtgtctcta aacataaatt ccgaatgaga
    10561 atacttcata ggctgattta acttgactag ctctgcctta ccagttgtct gattgacctt
    10621 gacataatag ccaatgccgt ccttacgatt ggttagccat ttccagaagg atttgtactc
    10681 caagggagaa acacgataag ggagcttgcc gatcgtaatc tgacggtact catcagaaat
    10741 accaaactgc gataccttat caatggtccc aagataagta tctccaatct tttcagccga
    10801 atctcgatcc agcaatgcca aggctgacag atcagtgtct ggaaaatcct tgttaaaatc
    10861 agcgtccttt accttaatca catgagcata ggacttagca cgaaacattc tagtattaac
    10921 agctaacagc aaggacaagc cagcaatgat aacagcaagg gcaagaccaa gccactttat
    10981 gccaccggtt aattgcttga gtgaaagacc tgaggtcacg tccttgcggc cagacttttg
    11041 cgtgaaaaag ctggtcactg tttttttcaa cccaaacaag gacaggataa aaagactcac
    11101 catcgccaag ataagcgcaa gaatcacgaa aaaccaaaat tctaagctca tcacgttcat
    11161 tggcggcaaa taaatccagt aaaagccagc caggatcaag ctgtctaagc caatcagcac
    11221 caaagaagca actttttttg tcatactaat ctcctcgtca caccctaagg ctatcagggg
    11281 tattcaatat cttctcaccg ctattgtacc acatttcccc tcaaaagatg acatctcagc
    11341 cagacatttt tatcagctct tagagcacct cagctagaat gatcaataca gctgacaggc
    11401 tacgctcata gagcttgctt agtacttctt ttgacgctgg caagagcctg ctgctccaag
    11461 actgagcaag cctagcagga ctagattgac cgctgcttgc tcacccgttg atggtaggac
    11521 ttgggctttt ttaactgctt gtgctgttag ggcagagcta gtgattgatg agccggtata
    11581 atgagtcaag cctccagcct gatgttctag ctgaggctgc ttagctttga taacctcaaa
    11641 ggtaagctca atcacgccat tatgtgatac ctctagacct ccttgaccga ttagctgata
    11701 gccctccggt agctcaacga ggacctcata gcttccttgt cgcagtgttt taccataggc
    11761 acttggaaca tagagagacg gagctagaga aatcaactga ccatttgctg ctttcaggct
    11821 gaccctgctg ccttctggca agacttggtt aaacaagagc caaacagaag ccacaatagg
    11881 ccttgtcatc tcaaaggcaa ctgaagcaag ccttgtatcc gcatctagac taaagctaac
    11941 caagttgtca gaccttagct caaacagatg attatcataa gccaagagct caacggtgta
    12001 gcgtccaaat ggcaatatca agctattagc tgagctattg aaatagtcca actgctcgat
    12061 tggcttgccc tgctcatcac gaataagata agtaaaggct ggctcttttt tgttctcaag
    12121 cacatcaagt gccaaggcaa cggacactac tcccttgtct ggtcctacag ctcgcaaagc
    12181 agctaagctc atataagcaa tctgacctgc ctcgtcttcc actagataat aataatctgc
    12241 ttctgcaacg ccttcaacct taggaatggt gtaggtgccg tctgcatttt gagcaatcat
    12301 caccttatta tccttgaatc tgatcagctg atcttcgaca gttagatcaa acttgcgtcc
    12361 atctttcttg acaaggtaga agacctcttc tctaacaata cctattggac tttgtccctt
    12421 gcttggtccc ggacgaaaga cctcagtagc accatcagct tggaagctag ctggcgtaat
    12481 gactggcttt tgatggctaa ctgtcaccgc ataggcctct gcttgaggca taccattagc
    12541 gtctagataa gaaacaacat agcgataatg tcctgacatc accctagctc ctgaggctct
    12601 tgtgccatac caagcggtgc tgtcaacatt agccacgctt gcacctggtt ggctagacca
    12661 gattgggctt gtcatagctg tatcctcctg ggcaaagacc gttaccttta gatcttgata
    12721 tacttgatgt ggcaagccct tgaatgccac aaaatccttg tttccatcat cattcggcga
    12781 gatgacagca gtttgaccta atttagccaa acgactctgt ggtctattgc ggctaataat
    12841 gagaagctct gcttcatttg tcaccagtcc tgtatctgca gcagtcatgt tgaggttatc
    12901 actgtagctc agctgatgct gagcattaat atcagttagg gtcaatgcca gctcagcctg
    12961 accgattttt tctggcaagt gatttcccag cttagcaatg gcaacattgc ctgcaaaatc
    13021 ctcgaccatg taataaaaat caccaagcgc cacctgatca actggcagga caaaagagcc
    13081 atctgctaag cgctcaacaa actgcttatt gtctgatacg gtcacatact ttaagccatc
    13141 attaatggta atcgtataag gcttgtcatc ctttgtttcc aagtaaaaaa cactatctcg
    13201 aagaacacca gcctgaccgc gatcaagcca ctgagacggt ctgaagcgat gggtcacagg
    13261 gttatagctt gctgttccta gctccggcgt ttgacgatcc acaatcacct caaagaccat
    13321 ttcttgacgt ttcgctccta ccacatctgg ataataagaa accacataat ggtatttgcc
    13381 atctggtagg tcagctccgg tcagcgattt accactaaag cctgtttcta acagcgttgt
    13441 tgacttggca aagcgaatat cactgttaaa gtttttatcc ccttgaaggg ctgatgggct
    13501 cgtccagagc aactccttac ggtctgtatc tgttccctta tagaccctgg cttgcaggcc
    13561 ttggtattta cgtaagaaca cccctttgaa ggcagcaaag tcttgattgt tgtcgccatt
    13621 tggagagata gccaacacag gatagccaac tgcatttcgc tccaacacaa atttaccgtc
    13681 tttattacga aaggttccta gtgtgtgcaa gccattgtca gcaatagtag tcatagagac
    13741 attggtatct gtaccaacag tcaccagccc agtaaaatga ttgccgacat aaatctcgtc
    13801 ctttagccct gagctgtcaa aataaaagcc agtttttcct tgagccttta gctcataaat
    13861 agaggcttca acaacaggta ggttttcaaa ggctccctta aagccaacaa atggaatgtt
    13921 gatgttatcc ttgtgctcgt ccttgctatc cacaaagcga acaaagccct ctagataata
    13981 gccatttggc atttgcttag agagttcctc tgtaaagttt gaggcatcta gggtaatggt
    14041 aatggtcttg tgtccttgag caggtacgtc aacctgttct ccctgatagg ttttcagaga
    14101 tcttgaacgt aaggcaaaac gtccttcctt agtatccacc tgatcagtca acaattctgt
    14161 ctggtagcgc agcgacttag cctgattaga caagttatgg attgtcacct caaagcttat
    14221 ctgatcagtc acatttccaa gagaaatact gccatagttg tctttacctg tcaggtacag
    14281 accactggtt accgcggtct ctatattcaa gagccctgct ccctgctggc gtggcgatgt
    14341 ggtggtattg gtcttagggt tgatgtggat ctgagcatta ctcatcagta tatttttgac
    14401 cagatctgct agcttatcct tggcaagctg tggttgaagc gcttctagat attgcttgac
    14461 caaaaggctt gcccctgcaa tgtgtggggt tgccatacta gttcctgact ggctgccata
    14521 gtgatcatcg ttgaaggtcg agtaaatatc tccacctgga gcagtgatgt caggcttcaa
    14581 atagccatct gaggtcaagc cccagttaga gaaatagttc atctcatttc ccttttggct
    14641 aatggcctta gagacctcag catcaaaggt cagagtgcct gttccattgc catttaaagc
    14701 agccattgcc atgccaaatt catgagagat aaaggcagat ggcagcacca tcccctttga
    14761 actcagacgc atggtgcggt tagccttgcc tggctcattg ttaaaaatca agaccccagc
    14821 tgccccgtac tgcttggcct ctgctataat atcgtcgtat ttccgattag gatcacgctg
    14881 caccaagaca atcttgccac tcacttcgcg ttcttggtag ccttcttttg tcaaagcttt
    14941 gacataaaca aatgagtatg gtacatcaaa gccaagacta gtcttaatgt ccttgaaatc
    15001 aacagattcc aaatagatag cctttccatg atttaagtca gccctatctt tcaagccctc
    15061 caccgtcatc agacgctcta taatcacttt gttattaata gacgcaactg aggtaggagt
    15121 ccggcctgct gatggagccc ccactaagcc ataatcagga tttgtcacca acgggtctgc
    15181 atgatctgac ccaaaggcac gctcattacc tgcagcaacg accacagaga caccagcctg
    15241 ccttgccttt tcgatagctg ccatcagggc acgattccca ttcaattgag acccattggc
    15301 cgagcccaga cttaaattaa tcacatcagc gcccaatgcc acagcatctt cgatggcttt
    15361 aataaataag gggtccccag ttcccatcaa atcatgggta aaaacccgca taaacatgac
    15421 ctgagcctca ggagcaatgc ctaaaaagcg ttcgccagct gctgccgcct tgagcccatt
    15481 tccagctgca atgcctgtca catgcatgcc atgcgattca tatttgctgt catcatctgt
    15541 atcttgccag tcaatgatag ttcctcctga tgtgtcatca agcttgatga ccgtttcctg
    15601 aggtgcctct attgactgcg gacggttcct cctaatatca atctgctgca caatcacatc
    15661 aaaatccaag tcgtcaaggc cctcaaacgg atcgtccttt atctccttta ccttatcatt
    15721 gttttccaca tagttgtggg caaagactac cttatcgctt agccagacac cgtactgaat
    15781 gcctgctgct tttttgcgct ggtcaatatc tgcctttgat gtaaacttag cagctgctgg
    15841 atttgtaatg cgcatggcat ggtgactagc gtcaatacca gtatcaataa cagcaataac
    15901 cttaccttga cccttatagc ctctattcca agctccttct gtttttatcc agcggtgagt
    15961 atccatattt actggaggta gctcgcgcga ttcttcttgc tgcttgactg attggttaga
    16021 ttccgttagc gcttccattt cggaagaaac taatccagtc gccattgcct cctctgtctt
    16081 ttcctctgct ttacttgact ggctgtcgat gtcctgagca ttaacagcag ctccctcact
    16141 agcctgagag acagacaata cctcccttga ttcttgatgt tgtcctgctg acacgtgagc
    16201 tgagctaact ccctgctcct cagccacaac tgatcccatc cctgtcagaa aaaggattcc
    16261 gatcaacaca gaaaccattc ctgatttata tttcctcagt gagaagcgtt cttttttctc
    16321 cacttgatgt cctcctagat ttattaaaaa aggttatttt aaacaaatga ttcatttatg
    16381 ttttaatcaa taatgtctaa gctatttaac cattttttaa tcacaaaagc aataagacta
    16441 gaagctctca gtttatgtca ttttttaatc attcaactca ctgaaatgag gcctctcaga
    16501 acctgtctca tcaacagata aggctaaact cagccgctag acttcaaaaa tgtcacacca
    16561 tttttagaca ttacctgtcc tcatacctat aacagaacca agcttccaca gtcgccttgg
    16621 ccttattttt ttgttacaat ataggttaag attatcattt agaaagcgaa gaaaaatgaa
    16681 actcatctca tggaacattg attctttaaa tgctgcgctc actggtgaat ctcctagagc
    16741 cctcttatca cgcgctgtac ttgatactct cgtggcacag gacgctgata ttattgcaat
    16801 tcaagagaca aagctatctg ccaaaggccc taccaaaaag caccttgaga gcttgcttgg
    16861 ctactttcct aatcatctca atgtttggcg ttcatctgtt gagcccgcca gaaaaggcta
    16921 tgccggaacc atgttcctct ataaaaaaga gctcaatccc attgtcacat tcccagatat
    16981 cggagctcct accactatgg acgctgaagg gcgtatcatc accctagaat ttaacgattt
    17041 ctttgtcaca caggtctaca ccccaaatgc cggtgatggg cttagacgct tggaagagcg
    17101 ccagctctgg gaccaaaaat atgccgacta cctagcccag ctcgatgccc aaaagcctgt
    17161 tttggctact ggtgattaca acgttgccca caaggaaatc gacctggcta acccagctag
    17221 caaccaccgc tctccgggct ttacagatga ggagcggctt ggctttacga acctgcttaa
    17281 ccgagggttt acagatacct ttcgctttat tcatggcgat attccaaacg tttatagctg
    17341 gtgggcacag cgcagcaaga ccagtaaatt gaacaatacc ggctggagaa ttgattactg
    17401 gctcacgtca aatcggttga ttgataaggt tagtcgctca gagatgattt cctcaggaga
    17461 acgtcaggat cacacaccga ttttattaga aattgatcta tagactagaa gcattcggac
    17521 aaatcaaccc agacattaaa aaaaaatggc tctgcaagag aaccgttttt ttaatcgctt
    17581 aaagacctag atccttatag gctgttcgat accctacctg caagacctga ttatcctgta
    17641 agaggatcgg ccgcttaatc agcatgccat ctgttgccaa aagctccgct gcctcctcaa
    17701 cgctcagtga attaacctta tctttaagcc caagctcacg ataacgcata ccactggtat
    17761 tgaaaaagct tttgaggcta taatctgaat gctctagcca ttgtttcagc tgctcagctt
    17821 tagggggatt ggccttaata tcaatgatat caacctcaga aaccagggtc tttagctcag
    17881 caagggcttt ttgacaggta ctacactttg ggtattggta aatggtaatc attagctact
    17941 ccttattaac actaatttgc tcgtgcctga gcaaccaggc cttcttttca agtcctccag
    18001 catagccaat caagcgacca tcagcagcca gtacacgatg acagggaata aaaatactta
    18061 aaggattacg tcctatggca ccaccaacag cctgagccga acgacactgc aggcgcttgg
    18121 caagctcacc atagctcaag gtctctcccc atcttatcgt ctgcaattct cgccagacag
    18181 ctcgctgaaa atcagtaccc tgtggagata agcaatcaag catgggatag ggcttcctct
    18241 caaagtaagc gtcaagccac aaacaggctc tttttaacag ggcatgctgc tcctgccaga
    18301 tgggctgcac tttaatccca gcctgaaaat acctttgacc ttcaaaccag gctcctatca
    18361 aagcaacatc agtcgcaacc aaggatattt ttcctaaggg cgattgatac acacactcgt
    18421 acaatggcaa gatctgacct ccccacataa tagcttattc ccttgactat ttattataag
    18481 aaaaagccta gctaaaggca agaaggagcc ctctgacacc acaacaaacg catgaaaaaa
    18541 caatagcggc tctttcaatg ctgccataca atcgttagtg tcaaaagtcg cttactatac
    18601 agctgccccc cttgaaaaac gaagctggaa agacacaaca tgctaaagct gtttcacgcg
    18661 ctggtgcctg attagatgtt cttctaatta aaggccaatg ttctgattaa aaagtcattt
    18721 catgcgctga tacctactca aataaaaaca catagcgtgg ggctagacca atccctcaca
    18781 agtcatcaat agttcgtcta tgagctacac tttatcacat tgggataggc agacatattt
    18841 gccggctcag ttgtacttgc ctgatagcta accaaaagcc cgataagctt tttccgatcc
    18901 tatatcaata gctgtagcgg ctatcctcgc taatctcctg ataagcggct ctttcatggc
    18961 ttttcttaat tttttgatag gctaagcgct cgccatcaat tggtaccttg ccacagtaaa
    19021 caaagcctaa cttttcaatg atatgccgca tgacctgatt atgctcatga gtatctatcc
    19081 gaaaatctgg tccatgctgc ccctcaatga gcccttgcaa aaaggtctga gcaattccct
    19141 gaccagtcct atcactcagc accgccacac gatgaaaggt cacataacgg tggtgattat
    19201 gctgccacct gccatcataa atcttgtcgt aggcgtcctc ttggccatca ataacagccg
    19261 cataagcaac aatctgcccc tcaagcaaag ccacatagcc ctgcccttgc aacacatcag
    19321 cagcaatatc ctgataagca ggatacccat ctgctttctg ccattggctg gagcctgatt
    19381 gggctaaggc agacttagct gaattgatca ctgtcatgat ctgactaagc tcattaggaa
    19441 aagcaagtct aatctccatc gttcacactc acaatctatt ctgatttgat gatgctatgc
    19501 taccgcaaaa agccttacac cttgtcactc tgctagggac acctcatagc ggtatgcctg
    19561 cttctcatct cagctgagta tagcacaata gtcatcattt gacaaaaagc ctcttcaagg
    19621 attgccagca atcatgctat aataaagtaa atcacaaagg agaaccatta tgattaaaga
    19681 attttgtgct gaaaacctaa ccatgctaaa ccaattgacc agccagtcgg tcaatcgtgt
    19741 tgagctctgc gacaatcttg cagtcggtgg caccacaccc tcttatggtg tcatcaagga
    19801 agcctgcgac ctcctacatg acaagcagat tagtgtcgca acaatgatcc gcccaagagg
    19861 aggtgatttt gtctataacg accttgaatt gcgtgctatg gaagcagata tcttaaaggc
    19921 tatcgaagca ggaactgatg ccttggtcat aggcttactc actaaggaca accagcttga
    19981 caccgatgct atcgaacagc tcctaccagc tacacaagga ctccctctgg tttttcacat
    20041 ggcctttgac ctgattgctc gcgaccaaca aatcgcaagc ctagagcagc tcattgacta
    20101 tggctttgta cgaatcctgc ttcatggctc aagcgatacc agatccatct atgaaaacat
    20161 tgaccatatc aagcagttag tcaaggctgc tcagcaccga atcgaaatca tgattggtgg
    20221 aggtgtcaca gctgataact gccaagagct aagtcaacta acaggaacag ctattgtgca
    20281 tggcacaaaa atcatctaac tatcagctca aataaaggaa aagtcactcc ctacaaggag
    20341 gtaaataata gcagcccttc tcgttgaagg ccatacctga gcccttagac taggctccta
    20401 gcaaactaat agtataggac cttcgctgcc tttacatcaa aaaggctgcc gtccagaaaa
    20461 agagaaagcc acacattgat agaaaaccat agctggctct actactatca gtatctatca
    20521 tcagcttctg agctgcctaa aagtttcggt gatcattaac aagtacagac tatttgtttc
    20581 taaattagat cataaaacag acaattatag gaagcgacaa gtgaatcatt attcattttt
    20641 tattgattac tatgatacta taagtaagga tagcgctttc tttttgtctt tgctttgcct
    20701 gactattagg ctctagattt attttttacc atactaatat aagaatcgga ataaataatg
    20761 acaacaaggt atttttataa gctattgcta acgatgttga cactagcatt aggaggattt
    20821 tccctatctg cttgccactc caagattagt aagccctatc aagtcgctat ttttgacaag
    20881 gatcatgtta ggacctttat ggaaaaagct gacagtctgg tgcctgttga gaccatctct
    20941 cgaacacagc acaagctatt tgagcgagaa agctttaagc aggccaagca agggtatttt
    21001 gcaaagacaa gagaaggaaa tgacctcaag gttctgttaa ctcacattga tcaagcaagc
    21061 ctagaagaaa aagtccttca tgctgatggc aatgacgcct acacctctac aactgatggt
    21121 gattactttt acacaacagc tgtctttgcc gatcgtattg actgctacaa gtatgaccgc
    21181 cacttgaaaa aacaggctca caagtctatt ctaaatcaag acaccattaa tgccagcaat
    21241 cagtttctgg tgattgatga cgctctgtac ctgcttgtca gcgctgtaga catcaagagt
    21301 cagcagccca aaactgagct atggaaaatg gacaaatcct ttactatcac tgatcggata
    21361 gatctggacg aaagcactgc ctatctgcgc atggtcaacg tcggacgaac cctttacatt
    21421 acccaggctg ctgatggcat tttagaaact ggagaaccta gacctggtaa caaggtgatg
    21481 acctatgact tagatagcgg tcaaaagtcc tatctcatgc ttcatgtcaa tagtcctaga
    21541 gccatttacc accatgccaa aaccaatgag cttatcatcg aaaatgatca gcattataat
    21601 cctgactttg catggaccat ctaccagcta gataccggag aggagagaac cattcgcttt
    21661 gaggagctag ccggtcagga gacaagctct ccctacttta tgatgacctc aagcaactac
    21721 tacttcctct ttccaaaaag gctttaccga tacgattgta gtaaccatca gatgacctgc
    21781 atcaacctag atcagtacgg agtgacgcac gcccatgcct tgatcgctaa gcccacacca
    21841 taaatcacaa caggcctaat caccactcat tcatctacac cccaatgctt agacaaagca
    21901 gtgtactgac ccccaaaagt tggacacgac atattagtga aaggacttag ccctgtgcaa
    21961 tacagaacta aatcctttca ctaatatgtc gtgtccaact tttgggggtc agtacacttt
    22021 gggaaagtat gtatgaatct ccagaaaaaa taccttatca actacctcta tatgacaagt
    22081 atgagggaaa taatagttta tttagagata atgcctcacc aaattttagg gcggatgtca
    22141 aagatattac agctacttta gtggctgttt taagtaatgg ttatccaacc gggaaaagca
    22201 gtttttgtaa agactactgt cccgatgaaa tcagggcaag acaattaacc caattagcta
    22261 tttggtattt tacagatggt atttctgaag aaacgttgaa atcaaattat agtctaaatg
    22321 atcttgaatt tcaaggatta aagtatttaa tacaggctgg caaaactgct gggactagta
    22381 acaatcgaac tttagatatc tatatatcta aagatagaaa ttcaaaattt caaaatcttt
    22441 taggttctac cttagtagtt aaaactccag aaaacaaaga gaactgtcaa tgtactaaaa
    22501 tttatataga agaaaatgga aaagatggtt attatcttta catctatgag gatacgaata
    22561 aaaacgataa atatgacaaa aacaaagata aactactaca gaaaaaatac ataaaaaatg
    22621 ggaaagacgg caagcctggc ctaaatggtc aacgtgggcc tcagggcgaa cctgggaaac
    22681 aaggaccaca aggtcctaga ggtgataaag gggaaaccgg agaaaaagga caagatggta
    22741 aaccgggcaa acaaggtgat cgtggtccgg ctggacctca ggggcctaga ggtgacaaag
    22801 gggaaactgg agaaaaagga gaccctggac gtaatggtaa agacggtaaa ccaggtgaaa
    22861 aaggggatcc tgggcaacaa ggcattcctg ggcctaaggg tgatcctgga aaagatggag
    22921 aaaaaggtga acgtggggag caaggacctc gtggagaaaa tcccactcct accccagatc
    22981 caatgccaca accaatgcct gaccctgcac ctaaaccaga atccaagcca gaacctaagc
    23041 cgatacctca accagaggtt aagcctcagc cagagacaaa acctcaacaa ccaaacaagc
    23101 catcaaccat tactagccaa cctagcggca aagcactacc aaaaacaaac gacacaggca
    23161 gcttgataac agtattggga acaggcttgc tctctcttct tggactgggc ttcttaacta
    23221 gacgcaaaag aaaacaataa ttaaagcact atctatagct ttttaatcat tggctatcaa
    23281 acaaatcaca aaaaagctta tcgttttact cctaacgata agctttttcg tattctctat
    23341 tacttggtcc caatactatt tttccagctt taggctggtt ttgttaatcc aaaataatat
    23401 cagacaattt ccgttttaat taaaaaaaaa aaacgaaact gcggaagcta attatcagaa
    23461 aatgattcac agcttagagt caccatgtta agctattcta cggagaagaa aggtttggga
    23521 atgactattt ctaaactcaa aggagagaaa catgagaaaa acaatgaaga agatgctagc
    23581 agcctcgaca gtctgcatca tcatgtcggg cagctttatc ggaggcgcgg caagagtact
    23641 ggcagagcag tactatggct atgatgatgg aacaaaagac ggtggagact ggccagtatt
    23701 tttatatgta acaccaacaa atcaccccga aagaaaaacc gataaagagc actgtgtcta
    23761 ttgctttaac aggttaaata gttcacctga gctctgggaa tctcaattta aagatccaag
    23821 taagctaggt ataaaactcc ctatctatga aaagaaagaa ggagatgaaa gccttttaag
    23881 agctaaatct cagaagccca gtgataactt aacttcaaaa ttagttactg ttctttcaaa
    23941 tggctatcct aataagacat taggtaattt aagtgaagat caaagtcgcc gattaacaca
    24001 gctagctatt tggcacttta ctgatggata cgctacaaat catttcaaag atggttatca
    24061 tctaaacaaa gatgaagatt cagaattaaa aaagttaatt gaaactgctg aaaaaaactt
    24121 ccaaactaca gcacatacct atagcttaaa tctttatgta acttcatcat ataattatag
    24181 tacaggtaaa ttttatcaac atcttcttgg ttccacttta acaccaaaac ttccgaaccc
    24241 aaatccagga cctaaaccac caggtgggaa caatccacat catttaccag gtgaaaatgg
    24301 tcaaactaaa tatccagaag gagaaagcgg tgaggcagga gctcctaaaa agcccgagcc
    24361 taaaccagag cctaagccgg aaccaatgcc taagccagag cctaagccac aacctgagcc
    24421 tatgccagaa cctaagccta aaccggaacc tcagcctaaa ccagcgcctc aaccagaggt
    24481 taagcctcaa aaaccaacca agccatcaaa cactactagc cagtctagcg gcaagggact
    24541 accaagaaca aatgaagcag gcagtctaat gacaggactt ggaacaggct tactctctct
    24601 tctcggatta ggcttcctaa caagacgcaa aagaaaagac taagacacta aaagattatc
    24661 tatagtcgtt tagttgatca gtatctagtc taatacaaca caaaagcctt atcgcgccat
    24721 aaatggaacg ataaggcttt ttaagcttgg ttcaaaaagg gtaagacaac ttagtctagc
    24781 gatgtaaagg cttcatcagc acgcttgcta gtaccattaa ggtcatggct gctacaaaca
    24841 aggccaagaa ataaggccaa gcctcaccta gattaccgcc attttggaaa gtgctgatga
    24901 tggttaacac ccaatgttgt gggagtagct ttccaatcgc ctgcatataa ggcggcgtaa
    24961 tactaagcgg ccacaaacaa cccgccagca tagaggttgg catcacaatc agattagcca
    25021 attgactgct ttgttgcgca tttttagaaa ccgcaccaat cattaagcca aagcctatag
    25081 ctaacaaact ataaagaaag aaagtcaaca aaacaatggc tgttggaatg taaaagctga
    25141 catttgctac cctgagtaat cccagcataa tcactatttg tatcgcaaag gcaacaatac
    25201 caacacagac atagctcagc atgtattgaa ggcttgatag ccttgataag actaagcgat
    25261 tgtagatttg actggactta tcaagcaaga taccaccgta caagacactg gtgctgccta
    25321 gcattaggat caataaaaag ccagttgttg tcgaggaaac agacttactt tgggaacgat
    25381 cagctagggt gatttctttg accttgtagg atagcttcgt gttatgagct gaaatcttct
    25441 tgaaaacctc ttgattgcct gctgccgcat caccaatgat attgtaattc tccaagagat
    25501 aattagcctg cgccttaaac cattctgtta tttgactatc agcaatcgaa cgtagagcga
    25561 tcttttgagt gtctcctttt agaaccttct caccaaagcc cggctcaatg gtcagcacag
    25621 cctccagtgt cttggccttt aggtattgat caatagcctt ttcctctagc ctagtatata
    25681 tctgatattt tttattgtgc tttaattgcg acacaaactg cttggaaacc tgactcttat
    25741 ccttatctaa gatcccaatc ttagcttgac ttccccctgt aaagctcaag gacaaggcca
    25801 gcattgttgt tagcataggc aacaggataa aggtgatata gcttgttttt ttacgtctaa
    25861 ttttgataaa taaggcttta ataaaaggaa tcatgctgcc acctgctttc tcattctgac
    25921 caaagcaaag aggataaagg ctgttcctat accaagatta accattaagg taaccggtat
    25981 gggattggac tgcccaccaa aaataagata aaacaaacta tcattgaccc attttatcgg
    26041 ggaaatatta gacagctgat taatcaaggc gctatttaag gttgacaaag gaatatagct
    26101 tcctcccaaa aaggcaaaga caggaatgac tgcattagac gctaccgtca aaaaggattg
    26161 atttctaata ccagtcgcaa gcccgatacc gatggcaaca gacaaataaa ctagcgaggc
    26221 cgtcacaccg ataatctgcc agtcattagt cccccaatta acacgtaaca caaatcgggt
    26281 aaagacataa agaatggtta gctggactgc tgttgctagc ataccaccaa ttaattttcc
    26341 aagcaaaata gcactatttg agacccctgt caaataaatg cggctagcca ccccttgctg
    26401 acgatctgat agcaccagat tcatcgctga cataatgcta taaaaggtaa tcatggtaaa
    26461 catggaaata gcatagtaat ccgctgagct catgccttta ctggtttgca cagagctaga
    26521 ggcgatatag tctatttttc ttttcttgat gttgctaatg gcttctggat aaaggttagc
    26581 aatcgaatca taggtcttgg cattatccac atagatattg acaagcatat taatcaaatc
    26641 agcattctgt tggttaatgc tgttggtggt cacctcaatg ttttggtcgc tcttaacctc
    26701 tagagctgcc gtcaaggcgc cctcgctgac cttttgctta gccttagcga tatccttggt
    26761 ttctttagct tctaaatgaa gctctttatt taacagcttt aaaaacgtga taaagttctt
    26821 ttgatactct gtttccttgc cctcaagctg ataacgaacc gtcaatttag gaacagtagc
    26881 tgctgtatta aagctggact taaaagcaaa gcttaaaatc agaatcatca agataggaaa
    26941 aaccaccatc atcaacaaag cagtccgatc cctaaaaatc tgtaagcttt cttttttgat
    27001 taaatgaaat aagatcataa caacccctaa tctcttagct tcttaccagt caaatgcagg
    27061 aagatttctt ctaaattcaa atgcttatgc ctaatctcac taaaagcaat atgagcatct
    27121 gtcagctgac gaacaaccga gccaatgtct tcatgttcaa tcaggagaac tgcttcaagc
    27181 tcgttatcca tcagtctcca attgggctta ttagagagat cgattgcttg gtcagctgcg
    27241 actgtcacca tgatttgctt tgtgaaatca gactcatagc gtctttctag ctcggcctga
    27301 ctgccctctt caatcacctg accatgatcc ataatgtaaa tgtaatcaca taaggcctca
    27361 acctcttcca tgtagtgggt cgtgtaaata acagtagctc cttgctcatt taacaagcga
    27421 atagactcta aaatatgatt acgagactgt gggtcaatcc ctaccgtcgg ctcatcaaag
    27481 atgattagct taggagaatg caccaaagca caggcaatgt ttaaccgtct tttcatacct
    27541 cctgaaaact ggcttggaaa ctggcttgcc tgtgatttta accctacgaa ctccaagctt
    27601 tttaaaacct gctccttgag ctcacttccc tttaagccat agagagagcc gaaaagctca
    27661 acattctcat aggctgttaa atcaggataa acagcaatat cctgagggac atagccaatc
    27721 ttggaactaa tttttcgaat agatttataa gattgctgta aaacagtcac ttcgccagca
    27781 ttcaaaggga ttaaccctaa aatagcattg attaaggttg acttaccagc gccattaggc
    27841 cctaaaaggc cgtagattct cccttcctca attgtcagtg agacatgatc tattgccttt
    27901 ttgccgcctc gatagacctt gacaacatct tttaactcta caaaactcat atattattcc
    27961 ttctttccaa ctctaacgct gctctttaaa actaattaac agataagtta aggtcaataa
    28021 aagcgaacca atcaaccaac catataataa ggctgctgtc acacaccaga caccaatcac
    28081 actaaagagg catagggcta gtagctgctg tagccagcct gagtaacgac aggccttgac
    28141 caaggcatag cccaaaacca caagcgtaag acctgccact gaatcttttc ctaaaaagag
    28201 acatagacct aagtaacaaa aagcatcaac cagtgtgaca agacttaaca aaagaaagct
    28261 agctgctgcc ctatctggtt taaaggctag ccaagtcatt tttcctaaga gcaggcgact
    28321 gtcctttttc agcataagat caaaaagcaa gaccaaaacc aacagggtca gctctaccaa
    28381 ggctatgcta tacaatagca cataacaaat gatttcccag ccaaaggata cgcgacccaa
    28441 aaaggtcagc aaaccatcaa gagctaaagc atcagaaaat aatagacaaa caagcactag
    28501 accaagctgg attagaccaa gcaatagatc aagccattgc tgataggaca ttgccctgat
    28561 gtgccttaaa tgccatctga ctaagcgccg tcttttatga cttgttagaa aaagggtcac
    28621 taggattaaa aaggatagca atgctagtat tatgatcatc gtaccacctt cttatgcatt
    28681 gattgaagat gactcaagcc ttcaacccat aaattgcctc caacatgaac aagcaacacc
    28741 agccataagc tctgactaac ataataaata cttccgtaaa taagaccagt cagtattttg
    28801 gcgtaaaaaa tggatctgcc catcaggaaa tggtttaggg catagcacag gctggtgatc
    28861 aacaagacaa gagcaattgg caatcgccat tgaagccaca agatgttaaa ccaaatcaaa
    28921 cgataggtga tttcctcaca gcaggccaaa accaagggat agcctatctg tggccatttt
    28981 tgtgtcgttc cgacaaatga taggactaag ggaagccact cttttttttg ccagcagcgg
    29041 ctaagatgta aaaaagcaac ctcaacaaag agcacaacaa agctcaagat aaaaccaatg
    29101 atcaaaagac gaccatcact atgacctaag ggcgctttaa taggaggtga cagcaggtaa
    29161 atccctgtta agactagggc ataataaacc agtacagctc ttaaaaaacc tattagatta
    29221 aagctatagc tatcacgacc ctggccaaaa atagcctgca ttgcgatcga aggacaaaag
    29281 gtagccatta aaaagcatag gttaaggcat tgggtgtaca aaggcatttg tcacacctcc
    29341 aaactgtctc atgcgtggat gattagcaaa tggaaaggca ggaatgcaca tctcaagaag
    29401 ctcaggagtg aggacacgtg tcacgtacca gcctttttct gaggcctcag gaggagtaat
    29461 gtctaaaaag acagcattag gacttacttt tttagtgtag gctagtagtg tctttaaatc
    29521 ctctttttta tctttcccag catggtttgt caggtcacta agacgaacct ctcctgaaat
    29581 caagggctca aaggccttcc atttaagctc ctgatccttt ggatgagcat agtaaaagac
    29641 gttactatct aggtctaaaa acaagggaga gtcactctca gcattttgtg ttgacgttgg
    29701 attataaaac aaattatagt aatagctata gctaatagct gaagcttcca tgattcctct
    29761 taacagggta tgcttaggat ccaagcccgc ctgaacccca aataagagat aaggaccttc
    29821 attggacttg tttttaagga taataccaaa ggtataaagc ggattatctt ctccaacagt
    29881 catgtcaata gggataatct cataaagact gtccttacca agtctagcct cttccaaaag
    29941 agctagaatt tccggatcat caataatcac tctgggacaa ggctttttag tatgccagct
    30001 aagcatcata gagtcgattt gaatatactc aatcaagcta ttacacatgg ctgcttccag
    30061 cgttgtatga gaggctgtcc ccgttgaaaa gcctggaatg atgtgctttt cgcctacagc
    30121 ctgattggtc ttatagccaa cgcaaagcat ttgggcaggc acatacatct ccttatcttc
    30181 aaaaaacatc ggacacttaa cccagcccaa gacatcgtct tgcgtcacca ttttatcaca
    30241 catgatcatg tgcaaatcat ggcaacggtc aatttgttcc tgcgtaaaaa cctgcaaata
    30301 ctctaagggc atgacaggat ccgtctggct caattcctta taagaagcat aaacaatccg
    30361 gtctgataat aattccccag caataacagt ggcataacgc tcaatgcttt cacctaagta
    30421 tttgatcaag gcttcctcat aatgactgcc ataaccaatg atatgatagc tcacctgact
    30481 cagctcacca ataaattgct tgtggtagtc aggcatctgt cctgtcacac tctttaagta
    30541 aacatcatga ggatggttac aaataggaac ctgagattga tttaagatac cagttcggtt
    30601 accactaagg ccctttagct tatcaagaat atggttgaac gaagggtaat aatgtagcat
    30661 ccttagacct ccttatgact cttcttgaag gagtttttta acaatctcac gtgttgaaat
    30721 ctgttgatcc tcatacctta attttgtcag agccccttgt gtctgagaat tagacatttt
    30781 caaaatatcc tgcacctgaa tctcaagcgt tggcaaatag acacttaaca aacgcccttc
    30841 aaattttgag cttcctgttt gagcaataat aaaggcctca ctgacaacca gattcattaa
    30901 cacatttaac aaaggtacat aagaggagct aacaggctgt gttggcggca actgctgact
    30961 tgcaaagcgc tgataaagcg tgtgatcctg taaacgtgcc agcacccttc tctccaagct
    31021 atcaaaatca gcactatgag gaggatttaa ggtacaagca tggataaacg gcccatcaac
    31081 aaagccaagc accaattgtt ttttcaaggc cacactgatt tcattaaggt gacgcagcat
    31141 cataatattc aaccggcctt gacaaataac aatactctga tagtctgcga gcttctcaga
    31201 taagcacttc atgttgcgat ggtgctccag agcatctaag cgagaggtaa catctgtttc
    31261 ttgaatgagc atttttagct catcgctagc cacctgaagg tttaagttca ggtgcttggc
    31321 cagcagctca gcagattcat tgacatagct tgaatcactg ataaataaga caggtgcagt
    31381 atccttagcc tgtcctgatt cagctatgaa atgataattg cctgttaaga ccttcatgat
    31441 attttcttca agagcataag cgtcttcaag catcaatagg tcgttataat acaaggctgt
    31501 gatgacctct gacaattttg caaataagtc agactctagt gttttttcgt aggtatcagt
    31561 atcaataact ttcccgttaa accaatcgga gatgatactg tagtaggctt cttttaaggc
    31621 ttgtggctct tgtgcaatgt ctaaaacagc ttcattaaaa tcccataggc cttttctaaa
    31681 gcaaaacgta tcgtcaaatt gcacaatgcg aacattgcta tttaattgat atttcattga
    31741 gactccttat ttccaataat cgtcatgtga atcacatgct gggtcaagcc atccaagcct
    31801 agcttttctt ggaggtattc cttattgtac cctccaatat caacacttcc atataccaaa
    31861 gctgttgaga ccaattgaac attttgagca atctctccag cttcaataaa ggcataagca
    31921 gtagcttgat ttccatattt acgtgtgttt ttgatgtact gataaacata gataagaatg
    31981 acattgcagt tttcggcagt gatcggtccg tattcggcaa aggctctaat atcctcctga
    32041 tcactaagat gatgacacct cagcgcgtgc tgataaggaa ggtattcata aaaaccgtcc
    32101 ttgagtgttt ctacgtttct tgcatagaaa aataaggtga tggggtacag acccccacca
    32161 gaagcacaat ttcttaaggc tactgtctta gtcatgcctt ctttgatgat tgcctgagag
    32221 ctgacaccac aagcataata aagcaaatca gccaaatcct gcaaaggcat ctcctcatct
    32281 ataaactgcc tatgacttct ccggttggtg atacaggttg atagggctgc tgagaccttc
    32341 ttagctttag gaagtgctat cgtgtttgcc ctatcctcaa aatagtcact atttgaaaag
    32401 gtggtcactg cagaatccgt aaaaaactca gccacactgg tcttaaaccc taggtaattg
    32461 ttattagcct tgtaattcat caaaaaccgt tggctaagat tgtctgtttc atcaggcatc
    32521 aaatgctgtg ccacaagctg ttttgatgtt tttaataccg tttgatgatg ataggttgat
    32581 aacgataagt gattggtatt aaattcaaat aactgtcgtg cttcttctct tgttaggtca
    32641 ctttggttat ccgaacgttg tttttcctta gaaaaaaatg gcataactgt cttcctgtaa
    32701 tatattaata aataatagta attagcaggt accgactagt acctgctaat tactacaaga
    32761 cgttgacatc aagctgattg tcttcgtctc ttgtcatgta acacccctat ccaacaccag
    32821 ctaacaccat caattacaaa ctgtaacctt agtcgctagc aaactaatga ttgtgaccta
    32881 gctattaact attaaataga agtattaaag tttacgcttt tggctcagct gcaccataat
    32941 tgttgtttat ggtagtattg ccccatgaag ctgagacgca gcaacaacaa gaacagcaac
    33001 agcagcaacc accaggagca acttgagttg tttctgctac actagtagct aaaatatttg
    33061 aagcaaattg taacataatg cttacctcct tatatcgcct gatcggtaaa acaaaacact
    33121 gataagagtt aaatgagaat acctctcaac tgatagcaaa agcaatcatg agcaggtatc
    33181 cagcaacaca aggctagcta ttttgtatcg cccttgttaa agtgaccatt caattcttac
    33241 caactatatt atattaaaat tcaagacata tgtaaatact ttctttaata ttttcttaca
    33301 aaaatgtcat tatttttcca gaaaggttag cttattgagc ttgacaaagt cttaagccta
    33361 tctctttaat ggcatttata aactatcagt ctttttaatg aaacgcatta aaataggtag
    33421 agatattatt atctctacct aaactgtatt gatgagacag atggctagta cctcacaatt
    33481 aaccatttct aaaaataatg actcttttgt cgaaagacct aatgattaaa gctatttgtc
    33541 tttgtttatc tttttctcat tagtaacatt aaatcatggc aaaatattta tattcattta
    33601 ataatcaaga ttccggatca tcaagtgacc gtccatgcag acctttttcg cgctgcacct
    33661 gtcttaattt ctcaggagta acatcgtttc cgtcttcatc aacaatctta atgccttcaa
    33721 tgtgatggcg cactgagcgg cgatagccct caatgtattc ctcacgcagc ttggcctgct
    33781 ctaccttttc aggaccagtc aagccaactg tttttttctt ttttgcaagc tcgttaatac
    33841 gagcgatttt tttaggatcc ataaatcaca tataagggct gcaccaaaag cagtgagcag
    33901 ctgatgaggc ttgatgatgg gctagacagc ctctttagga ccgttactag gacctttcaa
    33961 gtcctttttc accagctgtg ccagcaaggg ctgcctgcaa atggggctgc ctctaatcct
    34021 ttctctttcg tttgtgacat agagtactgc actctttttg tctatatcta aggctgtgcc
    34081 agcagctgct tagccttatg cttctgccaa gaaggctgta gcaagcttct tgtgaaaagc
    34141 taaaatccat gctcacttta ctaacagtgt tcctgatgct tttattgacc actgaccagc
    34201 acagctattg ctagcaaagc tagcccaaga cgatatctcg tagtaagcaa gaggactgat
    34261 ttgactaagt atcaattgct tgataagtct tgagtgctta gggaaggact tatcccaagg
    34321 caggtaatca gtcacctata tcatctaggg aatacgaaca gctaacacag ggcgatgtgc
    34381 ttaatcttac acagcgaatt atttagtatt taatcggtca aaggccgcaa tggtctctac
    34441 ctttttaacc agctctgcta acagcgctaa acggttacgt ctaatagctt cgtcctctgt
    34501 catgaccatc gtatggtcaa aaaagtcatc aataactgga ctaagggcaa agacctgagc
    34561 tagctgttct ttggctgatc cagatagcac tagtgaatca acagcctgtg ccaaagccct
    34621 ttcgtagtca ttttcaaaga ggctagcatc aatcagcaca gcgtcaactg cctttttcgc
    34681 tagattaaag acgcgagaca gcgactcgac agcaggcttg taggtgtcta gctggcttgc
    34741 cgcagccaga gcctccgctc ttgctaacag ttctggtaca acaaagcttg agctagccag
    34801 aactgcttca cgtatatcct ttggaatggc tgagcccatc attttatcca cacgtgcaca
    34861 aataaagtcc agcacctcag ccttatgctg ataggtcaag ctatcaaatg acagctcata
    34921 taggctatca atcagcttat ccataggaat gctccagccg aaatgctcaa gaattcggac
    34981 gatcccctga gttgcacgac gtagggcata agggtcattt gagcctgacg gtatcaaacc
    35041 aacagagaaa aaggacagca gggtgtctag cttatcagca agagcaagga cagcaccaac
    35101 ctttgtttca ggcagctctc cttctgccga atttggcaaa taatgctcac gaattgctgt
    35161 tgcgacagca gcagcttcgc cagttaaaag ggcgtatttc tcccccataa tgccctgcaa
    35221 ctcatcaaat tccccaacca taccagttag aaggtcaaat ttataaatct gggcagcacg
    35281 agcgacagca cttttttctg cttctgagag cccagcctgg tcagcaagaa aggctgcaat
    35341 aaccttggtc cgctccatat gctcagccac agagcctatc ttttcatgga aggtcacatg
    35401 agctagctta gcaaccaaat cttcaataga taacttttga tcctcacgcc agaaaaattc
    35461 tccatcttca agacgagcaa caagcacctt ttcattgccc ttaatcacat tttgaagatg
    35521 cttagcatta ccgttacgaa cagaaataaa attcggcatt agcttgccag cctgatcacg
    35581 cacgacaaaa taacgctgat ggttcttcat tgaggttact agaacctctt ctgggatttc
    35641 caggtacttg ggatcaaaac ttcccatgaa ggcagttggg tattctacta ggttgagcac
    35701 ctcatttaag aggtcctcat caatatccac ctgaaccttt tgctctgctt cgatggctct
    35761 gatttgtgct atgatcatct cttgacgctc cttagcagag gcaatgacaa attggctgcg
    35821 caggtcagcc tcataggaat cagcacttgt aatgctagtc tcttctccaa ggaagcgatg
    35881 tccgcgactg atacgtcccg aatgaatgtc taaaaagtca agctccaaag gctcatcatc
    35941 taacagtaca atcaagctat gcaccggacg aatatagtca aagctattgt tagcccagtg
    36001 catgctgact gggaaggtca aggaagcaag aacctctggc accgctgcta agacgtcctt
    36061 agcctgcttg cccgcttcat gcttggtgac ataaacgtat tcctcacctt tgacctctcg
    36121 gaattcgatg tcatcaacag tcaagccctt tccacgaaca aagccctgag cggcttttga
    36181 aaattgacca tctgcgtcaa gagcaatttt tttagagggt cccttaaaat cctctgtcag
    36241 atcagtctgc tgatcagcta agcccagcac acgcactgct aaacgacggg gcgttgaaaa
    36301 gccttcgatt gcgtcatagc taagccgatt ggccttaaga aaatcagcca tacgttcaac
    36361 aagctgcttt tcactaggtg tgacaacgta ggcaggaagc tcttcaagac caagttctac
    36421 aagtaaatct tttgtcatca ttaaaatcct atgggcatca aatctaaaag agaagaccaa
    36481 accgatccta gcatgccttg ggcaagcttg gacgatcctt tgtctacaag atttgtccca
    36541 tctttctttc ctttcttcaa gttatggggt aggtttagga gaccaaatca ctagctccta
    36601 atcctgcaag cctgctaata agctgcctgt tagacaagat cacttagcag aaagactgag
    36661 cttaacagga ctagtcatca ggcctttaag tctcatcgct tttaaaaagc acctaccaga
    36721 taggtaagct gctagcagca actagagctt acaagatcat acaagctgca ttgactacaa
    36781 ggaactagtt tagatccagc tgcttagtcc tctgccagca aggctactcg gctagcatca
    36841 tccaacaatg ggaagccaag ctttttacgc tctgcaacaa aggttttagc aacgctacga
    36901 gctaaatgac gaatccgagc aatatagcca gcacgctctg tcacagagac tgcaccacga
    36961 gcgtcaagca ggttaaaggt atgagagcat ttcaagacat agtcataggc tgggtggaca
    37021 agcccttgtg ctaaagcacg ctctgcttct ttttcaaata tctcaaagtt ttcaagcagc
    37081 atgtcctgat tggatacctc aaaggaatac ttggaatgct catattctgg ctgaagaaaa
    37141 atctcgccgt acttaacacc aggtgcccat tcgatatcat agaccgaatc cacctcttga
    37201 atgtatgagg ccaagcgctc taagccatag gtgacctctg ctgtcactgg tgatgttgct
    37261 aggcctccca cctgctggaa gtaggtaaat tgtgtaatct ccataccatc aagccagacc
    37321 tcccagccaa gtccagctga gccggttgaa ggattttccc agttgtcctc aacaaatcga
    37381 atatcatgct ccaatggatc aatgccaagt ctttcaagag attgcaggta aagctcctga
    37441 atattacttg gagaaggctt catcaccact tgaaattgat ggtgctgata cagacgattg
    37501 ggattttcgc cgtatcggcc gtcagcagga cgacgagatg gctccacata ggcagcattc
    37561 caaggctctg gaccaatagc gcgaaggaag gtataaggac tcatggttcc cgctcctttt
    37621 tcattgtcat aggcttgcat tagcatacaa ccttgatcat tccaatattg ctgtagcgtc
    37681 aaaataatct cttgaaaggt aagtttgtta ctcatgattt cctctttcta ttttttatgt
    37741 cttgtcgcag gcgctaacca agagctggct atggcttgac tgctggttgg ctcttaaaca
    37801 gcttttcaaa gagaaaaacc gcgcctatag ccacctacac ctaaaggcat aggggcgtca
    37861 aaacgcggtt ccaccctaat ttattacttc atttgatctt gttgataaac agatgtcaag
    37921 caagctacaa acacctgagc ctactcttta gagaaagcgc caaccagcag taccatcact
    37981 cggctctcac cagccccgag ctcgctttag atcagaaacc tgctattttc tttcctattg
    38041 gttagtttat cacaaaatcc tatgattgtc taatcaacta ttatgatttt ggacgagttc
    38101 cgtttggaat aataacctca gacaagagcc tattttcttc acgaatgcgc agataaatca
    38161 caataatata gcaagggaaa agcagcattg ccgtaatctg agcatggcaa agcaaagcaa
    38221 taccaaccag ctctggagca atgtttaaaa agtaattggg gtgcttaaca gtcttaaaga
    38281 gccaatgatc gacatattta tggtcctttg ccagcatcag cttcactgtc caaatatctc
    38341 ccaagatccg agttacctca tatagcacag ctatcgaaaa aatcatcagc agcaagccaa
    38401 gaaagctaat gccatcaaac ttaatctgct tgagcaatgc ctctgtcaca gcaaagacat
    38461 aaatcatgat atgcagcagg gtcaaaaact tagtgttttg cgcaccaaat tccttgcccc
    38521 cattagccag gatagccttc tcgtttttga tcgatttttt taagaatact aaacgaatag
    38581 caaacatcaa gagcatcaat aacaggataa tcaaagtaag actcctttat tctagtttaa
    38641 tctgtttctt tcacgaaaca ctaattaaga ttatagctaa gttacacagc cttgtcaaac
    38701 cgttttcaaa aaaaagatgt ctttctttga tctctaaaaa caagaggtcg tcacacagca
    38761 ccatcaagag acctcatcaa agctttaagg tcgtaccaaa tcaccatcaa aagacagctc
    38821 ctagactcag tcaattcacg agcagcaagc agcacccaag aggcattttg caggcctgac
    38881 ctacttcgcc tgtcgtaaac acaaatcctc aatatggtaa atagcgtcac attgcgctgc
    38941 aacctcatcg ctgtgtgttg ccattaagac aatcatatcc tcagtctgac aagctctgat
    39001 ggcttgtaag acctcctgct cagcctcaat atccagggcg cctgttggct catctgccaa
    39061 taacagctgc ggtgttttga ccaaagcacg agcaaggacc actaatgtag ctcacttaat
    39121 ccctgcagct cttgctaaaa gtccttggta tcaggatctg ggatagctga catacccggc
    39181 aggcaacgaa tgcgctctga atcctctgga ctaatctcac aatcaaaaat agccatattt
    39241 tctactatgc gttccttgtg caccgactta ggtagaggaa taaagccctc agcaatagac
    39301 caagcaaggg ctagctgagc cactgtcttg ttgtactttt tagccaatgc ctgcatggta
    39361 tcatcggcaa atatctctcc ttgtcctaat ggaccccagg cctctagcaa aatgtgatgc
    39421 ctgcggcaat aatcaaccgt ctctttttga tagcagccag gcgccaagcg aatctgattg
    39481 actgctggtg taatggttgc tgtctgttta agagcctcca gatggtgaac cataaagttg
    39541 ctgacaccaa tcgagcgaac caagcctgct tcaacagcct cctccatata agaccaagct
    39601 gctgcattgg ctgcttgcca gcaatcccta agagccttag gatttggcca atgaatcaga
    39661 taaaggtcta catactctag tccaaggcgc tcaagagagg ctgctaaggc tgccttagcg
    39721 ccatcatagc tatgagcatc attccagagc ttagtggtaa taaagagttc ttcacgagga
    39781 acgcccgaat cccgaatggc ctgtccaaca cttttttcat tgtgataaat ggcagctgtg
    39841 tcaatatgac gatagcctgc cttaatcgct gctagggtgg attggtaggc ctcctcacca
    39901 tcagcagcct taaaggtccc aaagccaagc actggaatag caagaccatt agccattgtt
    39961 actgttttaa tcatatctaa aacctccttt ttcattgtag cacaatgata agcaaagcaa
    40021 aaagaattga gctgatcacc agcccaattc ctttgctgta ttaagcctca aaggcctttt
    40081 gaccatttag gtaggttgct actaattcta agtccttatc aagaacaata aagtcagcag
    40141 catgacctgc cttgatttgg ccacagacat cttcaatacc aaccgaagca gctgggacgt
    40201 aagaggacat gtgaattgct tctgctggac ttgcaattcc ccaggcaaca acatttttaa
    40261 tgccgtcctt taattttaag atagagcctg ctagattacc actatccttc aagcgagctg
    40321 tgccattttc cacaataacc ggaaactctc caagcatgta atcaccatct ggtgaaccgc
    40381 ctgcacgcat acagtccgta atcaaagcca catgctcatg acccttttgc tgcatcaaaa
    40441 tatcgcaagc aacaggtgag acatgatgac catcgcagat cagctctgca accgttccag
    40501 gaatattata aacagcccca accataccag gctcacgatg agtcaagcca cgcatcccat
    40561 tgtaggcatg aacccaaaca ctagctcctg ctgctactgc ctttttagcc tcagtatagg
    40621 taccatttga gtgacctaaa gctactgtga caccctgctt ggtcacctca gagacaaatg
    40681 cttctacgcc atcacgctca ggagccaaag ctattttttt gatcaagccc ttagctgctt
    40741 tttgccaagc tgcaaattcg tctaagcgag gatttttcat atatatcggg ttttgggctc
    40801 ccttgtattc ctcagtgaag taaggccctt caaaataaat cccctgaatc tttgctcctt
    40861 tgacctgatc ggcaacagaa gcaacggttg cagacacctg ctctagatgc tcaaaggttg
    40921 acgttagggt agtcggtaag aaggaggtca ctcctgttga taagagaccc tcactgatgg
    40981 catggagacc ttctgctgaa ttatccatca catcagcacc agcatagcca tgaatatgag
    41041 tatctacaag tcctggtgct atttgatagc ctgtataatc aataacctct gcctgatcat
    41101 caacagtagc cgtccaataa ccaaatgtgc cattatttag ctccaaatag cctgctggct
    41161 ttacctcgtt ggggtaataa aagcaatctg ctttaatata gcttgtcatc ttttttcctc
    41221 cctttttcgt ttattatacg ccttaattct tattttgtaa atggtatata ccagtccttc
    41281 tgttaaaaag aaaaacctga atactatttc aagttttccc ttttattaga gctgtcctga
    41341 aagtactttc tcagctagat ttagggcgtg gtcagtgata cgtgtgtaat gagatataat
    41401 gtcaataaaa ttaatccctg cctgtgctgt gcattcgcca cgattgaggc gttcgatgtg
    41461 tgttttacgc aattgacgct ctttttgctc aatcgtccta tgacgctcaa caatagactg
    41521 ggctagagcc ttgtcactat ccacaatcgc cctaatcgca tctaaagtta aacagtgggt
    41581 caggtgatac atttctgtta attcaccacg tgcagctgct gaaaagccaa tctgctttgc
    41641 tgtaatcccc tcaatgagag tcgctaacga ctcagagtgg tcaccaattc gctccaaatc
    41701 acgagacgaa tccaacagac ctgctaaaac ctcattttca ctaggactaa gggcttcatt
    41761 ggaaatatca acgaggtaag tggtgagctc ctcatcaatc gtattgaccg ccttctcata
    41821 tcgcctcacc ttttcgccaa acttgtcttc tgctgtcata atgtagctat aagacgcctc
    41881 aaaagcctga atagcatagg aagccagatg taccaattcc ttgtgggcat ttcccaaggc
    41941 aatagaagga gcctgagtga ttagtaaacg gtccaaatac aaggcttcat atttgacgat
    42001 ttcgtcttca cctggaatta aggtggtcac aagctttgcc agagtgttga taaaaggaag
    42061 cagcaacagg gtatttgtga tgttaaaggt cccatgtgaa aaggcaatgg tcatctcagg
    42121 tgacagggcc aaaacagact gaagccatag cataaaggag gtaaatggca tcagtaaaat
    42181 cataaagatg accgtcccaa taacattaaa aagaatatga gcagcagcaa cacgcttagc
    42241 tgcaatatta gagccaatag ctgccaaaac cgctgtgata caggtaccaa tgttagagcc
    42301 aagcaaaata ggaatcgcac cctgcagggt caataggcca cccgaaaaaa gcccctgtaa
    42361 aataccaata atggccgccg aggattgaat cagcatggtc aatgctgtcc cgataaaaac
    42421 accctgaaag ggcttgtctc caagcgtcgc taggtaatgc tgaaaggctg agactgattt
    42481 taaaggatcc atcgcatcac ccatgaggtt gagagaaaag aaaattcctc ctacaccaaa
    42541 aatgatacga cctaggttat tgagtttttt atttgacgtg aaaaagagac aggctgctcc
    42601 aataaaaatc atgggcaggg cgtaatctcc cagcttaaaa ccaatcaaaa aggaggtcac
    42661 tgttgttcca atgttggccc ccatgacaat accaatcgcc tgctgtaggg ttaaaaggcc
    42721 tgcagatact aggccaactg taatcaccgt cacacccgag ctagactgaa tcaaagcaga
    42781 catagctatt ccaaccaaga taccaaagaa ggggttgctt gtgtacttgt caatgtaata
    42841 cctaagctta tcacctgcgg cctgctgcaa gtcgtctccc atgtatttga tactgaaaag
    42901 aaaaagacct aagccctgta ctgcccccca aaaaatgaaa cgcaatgtct tgccaattta
    42961 ccgacacaat attgtcctca ctcgcttatt tattctcttc tattttaatg tatttattca
    43021 gttatcacaa gggtttttta atccttttaa atagtgctca tttagaacct attttagagc
    43081 cctagtcctc ttttcatttt cctatattca gggtataata gtgctactca agcgacaatg
    43141 atttcaaagg agataccatg agaaaaccga caaaagagac ccactacctc atcattagct
    43201 tgcttactat tgccattgca ggaggggcct accttatttt tagtagcctc tctccaaagc
    43261 cagctaccat taccacccaa tctaagggct atgagctgtt aactaaggct caagcattag
    43321 tcaaggaggc cgaagacaac ccaactaaag aagctatcgc aaaggctcaa aaagcaatta
    43381 atcagctaaa aaagacccag tctaaggagg aattacaggc tcgactaaca gctatcagct
    43441 taaagcacaa tcaagaagac gttgctatca aggtcctaaa ggcagccgag gacaatccaa
    43501 gccctgaact taaggaggct gcacaaaaag ccattagtaa gctctctgat gaggctaaaa
    43561 aagctgcctt acaggctaga cttgacgcta ttggactttc aaagcctagc actgcacagc
    43621 ctgagactgc aacaccagca gcagaaaaaa atatagcacc agctcctgcg gctccacaaa
    43681 taaagcatac cacaccgtct tctgggggaa cgacgccagc accgaaccct aaacctagtc
    43741 ctaagccgaa tcctcagcct agtcctagtc cagctccaga gaacccagag ccaacgccta
    43801 gtcctaaccc tcagccaaat cctcaaccag aaaccaacac acctagccct cagccacctg
    43861 caacagagca aagtgaaaac actgctccag caggacaaaa ctaagaaagg gcagccagag
    43921 ctgctgtagc ttagttacac ttcttagtac aggcaataag ggcttagcta ctgaaataat
    43981 gctaaactta cgactaataa gctctctgat aaaaagaggc tttaggtgat taaaaacagc
    44041 tggttctaaa aggattccag ctgtttttgt gcttcttaat tgattttgag gtaggaagag
    44101 aagggaggct taatcaagtc gataagtaat cccatatcct ctcctaactc tctatcagct
    44161 tggctatgat tatagagcgg ctcaccctta cgcgctttgg tgattcgtca tggatattct
    44221 gactggcttg accatttgag ttttttcctc agtgtcactc cctaagactt ttaagggact
    44281 gacgaggtga ttagcatgca caacaaaaag cccttaaaca cacctttaag gaccttgtat
    44341 tcagcttaat gcctctatag tatcagggat atttgttaag gcagctctca gctaaagact
    44401 tgtgataaag acctatgcct atccgaccac tagctagagt caagctgtgc atagctcagc
    44461 ctctatgact aacagaaacc agaggcagcg ttagatcact ttgcttagct taaacctcat
    44521 agcccatgag aagcccttca gcttctgcat agaagctgca taggcctgag gctgggctgg
    44581 tttgaatctc tgcttctggg taaatcgctc taattttttc cgcaatttgc tcacagatct
    44641 tagggttttt ggcgtgggag ataaagactc ggcctccttt atagcctgcc ttttgaatct
    44701 cttctaaaac agctgacact gccttttttt gacctctggc cttttgaagc agctcaagcg
    44761 tgccttcctt acttgcctgt cctaccattc tgatgtttaa taagccaatc accttaccaa
    44821 tgagcttatt cagacggcca tttttaacca gattatcaac cttggccaac acaaaaacaa
    44881 gcctggtttt ttcctgataa gctgtaattt tctcaacaac ctcatcaaaa gaaagcccct
    44941 gattgatcaa ccgctctagc tctaacacaa tcaaatccat ctcaccacct gctgacaaag
    45001 agtcaatcac atggatattg gcattcggat tttcctcaag caagtcattt tgagccaatc
    45061 tagcactatt gtgactgcct gagagcgtac cggtaatggt aatggcaatg acgttatctg
    45121 ctcccctgta ggcttgtaaa aaagcatcag gacttgggca gcttgaggtt gctggcttag
    45181 aggactgata catagtctcc atcatttgat caatatctag accatcatca tctctaaaaa
    45241 tatctgaacc aatctgtagg gttagcggca cacgctcaaa gcgcaggtga ttggattggc
    45301 tttttagggc tctaatatcg cagcctgaat ccgatacaat tttccaggtc attcgttttc
    45361 ctcttttcct tcatagtctg ttttggttga caaagtaagc attttcccat aaaattatat
    45421 catcactagc tagacttttg ctagctaaac gacatcagat gtaacacttg aaaggtattt
    45481 gtaatggctg gtaaaccaat ttctaaacag tcccttcaaa atttagccca ctgcaatcag
    45541 gaatccagac ggttaacacg agaagctatt gaaattgctc tgcttagctt actagaaaag
    45601 aagcccttag gacacattac catttcagaa ttggtagcta gagctggggt ttcaagaaat
    45661 gctttttacc gcaattacag ctcaaaggag gatattcttg agtgtctgtt gacttctgtt
    45721 atcagacgta tctttcgtgg actgaaggcc tttgatctaa agacacaggc ctatcaggca
    45781 tggctttatc tgtttacaga ggccaaaaaa gaagcgacgc tacttagtat tatctttaac
    45841 catcacctgc agcagctctt gacgcagatg gttaccaagc gtttgagagc ctaccaaaag
    45901 tggcaggaaa aaaagctgtc tcactacgca ctgctctttt ggagcaacgc tattgtctca
    45961 gtcctttcca attggatttc tgatgatatg gttgttcctg ctgaggagat ggctgctatg
    46021 gggctgccct tattagccta gttgtctcta gatcacctat agctcctaga caacttccca
    46081 agaaaccaag cttgcagcat cagacaggac gcttggctgg cttgacttaa gcactggcac
    46141 tgcctaccaa gatatgtact agccctacta caggcaaggt gtgacttgtc gctcgctgtt
    46201 gtgcagaggc ttaaaggctc ttacatttag ctggacaata aaaaaagact gaagaggctg
    46261 gctggattag cctgctcttc aatccagaac ctcctttgtt ggaggttttt tcgtgtttta
    46321 tttttcagtc gatctcacac acctaggctt gtggtgttcc aagacagctc agctctagtc
    46381 aacacctcta aaactgagct tatcatctct agcttttgga ggccttttct gacgggctgg
    46441 tttgactgtg cttaagagcc ctttgtcaat gcaaattgat taatggcatg ggccacgcct
    46501 gcttgatcat tggagaggct taccttgtca gcgacctttt taattgcctc atcagcgttt
    46561 cccatagcga cacctaagcc agcataggct aacatttcaa gatcatttgc tgcatctcca
    46621 attgccatca cttggtctgg gcgcagcttc agatcagcgg ttaattcctt cagggcagag
    46681 gccttggtca cacactccgg cattacctct aggattgttt cttgactgcg aaccacacta
    46741 aagcttgcgc tgagtttttc tctaacaaga gcctcaaaag tatctagggc agccttttct
    46801 cccatgtaca tggcctgaaa tatgatttga ctgctgttgg ataactgaga taggttagta
    46861 gcctttacct ttgtaaaaac caaatcacca tcagcctgaa ccatatctgg aaccttgcta
    46921 tctatcacaa gataatcacg ctctccagtc agggtgaggt aaatatctga aaagggctga
    46981 gacagctgat aaaggtgctc aatagctgaa aaggtcaggc tttgataatg tagcagctcc
    47041 cagcttgggc tcctataggt gctacagcca ttgtttaaaa taaggtactc ctccttatca
    47101 ctcaagccta attgctcaaa atacggcctt gtcccagact gggggcggcc tgtgcagaga
    47161 acaactttta tcccctcttg tgcagctgct tggatagcct taatattctc ttttggaatg
    47221 tgctttttgc tatcaagcag agtaccgtct aaatcaattg ctataagctg aatcatcgtc
    47281 tcagtcctct ttccatttta tcttaggtag gtgccattgt cttttgttgc caatcatacg
    47341 catgactgtc aataaaacaa ccagcaagta gcattcaaca tttgaagtgg ccagcttaaa
    47401 ataaagcaca agtgctgcta taatagacca gccagcataa atctcacttc taagaacagt
    47461 tggcttacgg cctgccagga catctctgac cacacctccg cctgcccctg taagaaccgc
    47521 tgctacaata acagcgctta agggctgggc tagtcgaaca gcatgtagag ccccctgaac
    47581 actaaaggct gcaagtccga tagcatcagt cagcaccgct gctctcaccc agcccttagc
    47641 cacaagctta ggaaatagca tgatcagaat aatagctata aaagcgcagg caaattctgg
    47701 tctttgtccc cacaaggctt caataggcag cccgatcagg gtatttctaa tagccccacc
    47761 accaaaggct gtgacaaagc ctagaataaa aatccccaga acatcaaact cctcctccat
    47821 agcgacaata gcgccggaca aggcaaaggc tatcgttcca ataatgctta aaagctccca
    47881 catatcaatt gtcataactc acctaatgct tcctaatccc ctattagtct accatctttt
    47941 taatcaaaat ataagtcaaa ataagagcaa ggtcctcaaa aatcctactg atgacctgtt
    48001 tttgtttgca ccaaagattt agcccctata taggctaggc tcctagtagc aggagttagg
    48061 agcgatagct tgccaaattc acagccttgt tattttccat gagaaagggc tctgctgatg
    48121 tcttggtttg ataggtcttg tatttatggt agaggtattg gtagcaatcc tgtttttgat
    48181 caaagaggat ggcttggtag ggctcttgga aggacaattt ctcaacaaac agatacttgc
    48241 tcttatactc cactagcact cccacatgac caataaaaag gtaatcacca tctagctgat
    48301 cgtgaatcac aacagcaagc attttggctg ggccattaaa gctaacagct gagaaatgct
    48361 cttgcatatg cttggcatgc acctgaatat ccttggtggc ttccgttttc actcttgaaa
    48421 acagctgctt aaagcgctct gtctctgcct gtgtaaagag ctggcttgtg gtaatggcgt
    48481 cctcgtccat aaataaaagc gtatcatcac tgctggtagg cgcaatcgtc atgctatcct
    48541 ttagaagcat aaaggtgttg atccggcaat tagttccaat gaaattgcct tgcttttgcg
    48601 accacaactc atcgattgct accacatcat agtcaggctg cttctgatag gtaaaggccc
    48661 ctgtcaagcc tgttttgcca actaggctat tatattcttg tacaccagcc ataaaggcat
    48721 tgacattagc ttccttcagc tgatgtgata gggcagccct gacctcctgc tggctctttg
    48781 cactgttcat gttggatagg aaaagacgtc ccttcttagc ctgtggctct ttttgctcct
    48841 gcttgggctg atcagactgg tgagaagcct ggcaagcccc aagagttgcc gtagcaagga
    48901 ttagcaaaga catcattact tttttcatca taacctcctt tttaatgagt cattcaagct
    48961 ggtactctcc atcatcacca aatgagatta tcagcagctg gcagctaata cgaggttgct
    49021 acaacccact tgttatctct ttatgtcatg acctcatcgt taccagtata gcataaaaaa
    49081 gaaaagcacc agctcttgaa gccttgcagc ccttgtgccg gtgcttttcg ttaggagatt
    49141 acactgaaat agtttttgtg gtagctagct gctgatacca ataagcgctt tttttagggt
    49201 aacgcttttg ggtttcaaaa tcaacataga agaggccata acgcttatca tagccatttg
    49261 accaagaaaa gacgtccatc aaggaccaga taaaatagcc cttaacatta gccccagcac
    49321 cgatagcgtc tgcaatcaca gccaaatgct gcttgatgta atcaattcta gcgtcatcat
    49381 caatcctgcc atcaatacag gtatccttgt agccaaggtc attttcagtg atataaatct
    49441 ttttatagcc tggatagtct gccttgatcc gcatgatttg atcgtaaagc ccctgtggat
    49501 agatcatcca atcccagtct gtacgcggca catcaacatc aaacacgcgt tgaccaaccc
    49561 cctttatctg atatttggag ccgccttttt ctcccttgcc attatgaatg atttcggtct
    49621 caccatggct aataataagc cagacttctc atcacgtacc ttagtggctg gcaggccata
    49681 ttcagggtct agcaggatag aggaggcata gggggttagc tcctctgata ccagagcctt
    49741 tagggcttcg atttgccaag gagctggctc tgtgtcttgg tgggctgcca tcatgcgctt
    49801 taaagccccg cgttgatcaa aggccaaggc cgaaatgatt cccttacgac tgaccttttc
    49861 taaataagct tttttgtttc ttgttaatgt catcttatac ctcctctact tgaatacggt
    49921 caaatagctc atcaaaatgt gccatgttaa catgacctgt tcttgtttct tgcgcattta
    49981 acatgcctaa aacattggct tttttcagaa gcgtctcatc gtcatctcct tctgccaaag
    50041 cccaagcaat ccctgccaca gtagcgtcac cagatccaac aggattgact acctcaattt
    50101 taggaatggt aacacggtaa aacctgttat gatgtttggc aaaggcccct tgggcaccaa
    50161 gagaaacaat aatccattct atcccttcaa ataaaggttg actcaacaga gagattaaac
    50221 gttcctcatc taatgtgaca ggttggccta tcaaatcctc caattcttcc aaattgggtt
    50281 tgataacagt tggtttatct ttgccagcca gtaccgcttt taaaggagca ccagagcaat
    50341 ctaaaaccac tttgctgcca tagactctcg ccatagtaat caagtcttga taatagtgag
    50401 cggccagacc cttaggcaga ctgcctgaaa aggttaagac atcaaactgc ttagcaataa
    50461 tactcatgtg gttcaaaaag ccttcggcct cgtccatatc aatgtaggga ccagcttcca
    50521 gaatttccgt ctgcatgcct tcatgtaaaa cagcaataca atttctcgtt tcccctttga
    50581 ttttgaagaa ttggttagaa atgccctgtt cttgtaactg atgaatgaca aagtcaccca
    50641 gtttcccacc aataaatcct gttgccacaa ctgactgacc agcttctgct aacactctgg
    50701 tcacattcag ccccttacca ccggctgttt ttgtcgttct gtcaacacga ttaaccgtgt
    50761 ccaaagtcag acgatttaga ggataggaaa tatcaatgga tgggtttaag gttaccgtta
    50821 aaatcatcgc ttctccctaa tcgtggtagt caccgcgatc ccatttgtcc aaaaactctg
    50881 taaagaagtc aggatcttct tggttagcat tatgactttc caaatgggct atcttagcaa
    50941 ttaacttctt attctcttcg gtttccttat agtctgcctt tataaaggcc tcaataatat
    51001 cacacatcaa aagctcacct gtgattttac caccaaagcc aatcacattg gcattcaatt
    51061 cttctttggc ataaagcgct gttgtcatat ccctaacaag cgctgagcga atgccaggaa
    51121 ccttgttgac agcattagtg atcccaacac cagtgccaca gatacagaca ccaagatcag
    51181 ctaggccatt ggcgacagcc tcaccaaccc ttttcccaaa aatcgggtaa tgggtgcggg
    51241 tatggtcata ggtcccacag tcaatcactt catagccctt tgatttcaaa aaatctgaaa
    51301 cagccatttt ttcatcagtc acaatatgat cacagccaat agcaattttc atgatatcct
    51361 cccttcgtta agccatttta ttgagcatgt caacacgaat ttgatgacgg ccaccatcat
    51421 agtgaccagt cacaaaacct ttagcaatat tcttagccaa ttcttgaccc acaatttctg
    51481 ctcccatggt aatcatgcgg gcattgttat gaccgcgagt catgtaggca gagcgttcat
    51541 ctgacacttc cgcagcgacc atacctttga ttttggtagc gaccataaat ggccctgctc
    51601 cataagcatc aatcataatg cctagacttt cctcatcagc cttgagcgcc ctagcaactg
    51661 ctagagtatt gtcaacaaag tcatcagcaa tcgccgtcac atctgtcaca tcaaagcctt
    51721 cctgctgcaa aaagccttta atagcctctt ttagatcatt tccatgtgca tctgcaccta
    51781 agataatagt cataggatct ccttttattg tcattaccgt tcaaaattgt ttatttttgt
    51841 tttgtttttt attattttgt tgtttattga aaaaagagac tgtttatgct attatgagtt
    51901 aacaatacac cagagaaagt agcggcctat gcttaagcgt gaaagattgt taacaattat
    51961 ggaaaaggta aacgccaacg gctttatcac tgtcactgat attatggaaa gcctaagggt
    52021 ttcagatatg acagccaggc gaaatttaga tgagctagca agggctggaa aattagtacg
    52081 tattcgtggc ggtgcccaga gcatttctat gcctcaaaag ctggagcgtt caaacactga
    52141 aaagctaacc gtacaaattg aagctaaaaa agagattgcc agatacgcta gtcagctcat
    52201 taatgatggt gagaccattt ttataggccc tgggacaaca ctagaatgct tggctgaggc
    52261 tctaatcaac cgtcacatcc gtattattac caacagtctg cctgttttta cgattcttaa
    52321 taaaagtaaa actgttgatc tcattcttat cggtggtgag taccgagcca tcacaggagc
    52381 ctttgttggc agccttgcaa gccagaccat cttatccttg aagtttgcca aggccttcat
    52441 cagctgcaac ggtatttata aaaatgacat tgccacctac agtgaaaacg aaggggttat
    52501 tcagcgccta gcctgtgaca atgccatcga aaaatacctg ctcgctgaca accaaaagtt
    52561 taacgcctat gacttttaca gcttttatca ccttgacaat atcgacgcca ttatcactga
    52621 ctccaagatt agtgacagcg ttaaggagcg ttaccgccaa tttgccaagc tcttaatcgc
    52681 aaggccagct gacaatcagg tcagcagcta gacagcctgc ctctctatct gtttccaccc
    52741 tgagtccagc aggtaaacaa agctatcaaa cgaaatagca tcataaaagc gcatgaagcc
    52801 actaatattg caatggggct tcatgccttt tttaacctat cacacgttaa gcaaagcaaa
    52861 aagaggctag gacaaaaatc cttcctcttt taaaatcgtc aaactataga gttgattgga
    52921 gggctcttag ccctcatttt tcaagcgatg tggccttttt aatcagctgc tcgagggtgg
    52981 ataacctaat caacatcgcc aggtcatgac gattgaatgg ttattccact ctttttctac
    53041 gctgagggct gtgaaagggc tcatacgaca gcttagccgc tttctaacag ctatttacct
    53101 acctcacctc ttaacgagca gacagcctaa atggtatagt ccagctgatc aagactcttt
    53161 ttatggtcaa ggtcaatatc aagaaaggtc atctgcttga tattgataag gctggctaca
    53221 attgataccg gaaaagcaac caccgcttga ttgaagagac taatattact attgacaatg
    53281 cgttttgctg ctgccaaggc tgcattttcc ttagcaatct cattttgcag gctcaaaaac
    53341 tgctcagagg agcgcatttc cggataagcc tctcctacag caaaaacctc attcaaggcc
    53401 tgctcctgtg tcctcatcac atcatttgtt tcctccaagg aaagcccctg acgcagcttc
    53461 acgagttcag taaagacctt ttcctcatgc ttggcatagg acttagcgat ttttagcatt
    53521 tccgaaatgg tatcatatct cttctcaaga gcaatatcga catttcgttt agactcctct
    53581 ataacgattc gatacctttc taatttgttt ctcactccaa taagccatag tatagtcatg
    53641 caaagaataa gtgttaacat agatgacgtc actgacataa aaaagcctcc ttaaagctga
    53701 tgatttagtg tatccaacaa gcggtacatc ttaacaagct tgtcttgaat gttttcatat
    53761 tcgctactta acgatagctt ttcaatagcc cctctagagc taggggtttt caagagctgt
    53821 tgaccggaat agaaggacac aacaacagta tcaccattca tataaactgc tacaggcatc
    53881 tcctctctcc attcatcaag cactgccagc atataaggat ttaagagcat tctagcgctt
    53941 aattcatctg tgcagtacac attgtacgtt tcattaaagc gaatgtcctc catttccagc
    54001 tgcacctcac cctttagctt agccttgtag ccactatgga ccttttctct gcccaaaaag
    54061 cccttttgag tcggcacaat tctaatataa cccttgatag ctgtatgata tttagccagc
    54121 agcacctgtc cgttaaaatc agtgacccga tgccagttat catcctcatt ttcctcatgg
    54181 taggcataaa gattgcaaaa ttctgtctgc atgtcatctc caaaaataat atggcaatta
    54241 ctgtcatacc atctggagga cggtgttgca agctttagta aggagagctc aatccctgaa
    54301 tagtaatcta tcttgacatc tggcagggcc tcttgtaaaa caggcagcaa aaagtgatcc
    54361 acataggaga gctcatttgc tgttttgaat gttttcagcc gcggccaaac caagcccccc
    54421 acaaagataa tgagaaataa ggcaagagat cggtcaacca tgccatacaa gatgattgcg
    54481 cctatcacca ttgccagcca gcccagatta ttctttctag catttccact catctcgctt
    54541 ttaatttgct ccagcttttg gtgatgctca ggcgaagctt ctatagctct actcttctcc
    54601 aaaacaatag gatctgtcaa tcgcttagta ttttcgttca tctcacttac tccagatact
    54661 tctccatcag cagcgctcag ctgctcttga taacaccagt cactttatgc ttttgcttaa
    54721 cctataaatg acaattgcgt tacagctaat ttataatatt ataccatttt taaactattt
    54781 tttctattat tatatttaaa tgacgctcaa taataaccac ataatgttaa tatagacatc
    54841 attgtgctct tttttaccta atcatgttgt gagcaatacc cccgtttatc agcggaaacc
    54901 ataaaggcct ctatgagatc aagactatca gcgccagccc ttcttttgga gtcactattc
    54961 agcttgttct tcgcatgctg tctttgcctg accatgattc agctgctctt tttgattgct
    55021 tgttatgctc actttttccg tctcatgctg agcaagaaaa aacagcaaac ccttgcttgg
    55081 tttactgctc ttctgttgat gttagtcaaa aaataagccg ggagctaatg acaccctatt
    55141 aactcataaa gcctgttatc ctttctttgt catagaacaa ttcacttagt ctattctcaa
    55201 ccaaaatacg aagcctgctt aaaccgtctt ctcatattaa cagctaaaaa gtggtgtcaa
    55261 tatgaagaaa cctatgatcg gtaacaataa tagcaccttt aaatctctca gcgataatgt
    55321 aaggttatcc tatacctgtc atatttttcg gtgctatttg ccatatcagg ttgctatagc
    55381 acttggtggc ttctggtagc cttaaccaat aaatgatctg cttttttatt cctgctcttt
    55441 gttttgttta tgccttttgt cggcgcaggc ctttagcttt actatactga cggtaaggtc
    55501 ggtgagagcc tttaccattt tttatgcctt aatcgcaaag catttaacac cactgatatt
    55561 gagctaaggc tcatcgcaaa gccagccagc attgggctta atagagggcc gccaaagaca
    55621 tgaaggatac ccatagcaac ggggatcatt aggctattat agctaaacgc ccaaaataaa
    55681 ttttgcttaa ccactctgat ggtttgacga ctgagctcta ggcattccac cacatcacgc
    55741 actgctgagg tcatcaggat aacatctgcc gcctcaatcg caatatccgt acctgagcct
    55801 attgagattc caatatccgc tagggtcaag gccggtgcgt cgttgattcc atcaccaacc
    55861 atagcaacca gctgtccgct agccttcaaa tccgcgataa tctgggcctt ttgagcaggc
    55921 agcacctgac taaagacctg atcaattccc acctcattag caatcgcttg agctgtgagg
    55981 gcattatctc ctgttagcat aaccgtttga agacctaaat cctgcaaggc ccttatagct
    56041 gccttactgt cagcctttag cctatcagca atcagcaata aagcacatag ctgattatcc
    56101 ttggcataat acactacggt ttgccccttt aaggcagctt gctcggcata ggtctgagca
    56161 gcgcttatcg caatcccctg ctgtgacatc agctcactat tgccaacagc taagcgatgc
    56221 tggtcaatca caccagtgac acccaagccc acaagcgatt gaaaatcagt cacagccagc
    56281 aagtcatagc ccttttcctg tgctactcta acaagcgctt ctccaagagg gtgctgcgaa
    56341 tactgctcta aggaagccac ctcctgaagt ccctgcttct cactagcagc aagggggatg
    56401 atccgctgta gctgagcctg accctctgtc agcgttcctg ttttatcaaa aacaattgtc
    56461 cgcacctgat aagccttctc taaaatatct cctcccttaa aaaggatccc ctgctcagct
    56521 gcacgacctg agccaaccat aatcgcggtg ggagttgcta gacccagagc acagggacaa
    56581 gcaataatca aaacagctat agctattgtc agggcaaaat caaagctctc tctcataaca
    56641 aagagccaaa aaagaaagct cagcagggat aaacttaata cgatagggac aaagactcct
    56701 gataccctat cagcaagtgc agcaatcgga gccttggctt gctgtgcttg ctccaccagc
    56761 tcaataatct gtgaaagcaa ggtgtcattg ccaagcctag agggctttac ccttagcgct
    56821 ccttggccat tgattgtgcc agcaaacaca ctatcacctg tcaccttatc aactggtagg
    56881 ctttctcctg ttagcatgga ctcatcaacc gtagactgcc cctctactat cagcccatca
    56941 acagccaccc gttcacccgg ttgaataaag caaatatcct cattagtcac ctgctctaag
    57001 ggaataagct gaagtgctcc ctcacgaata accctgacat cagttaccct taaggacatt
    57061 agcttctgaa tagcctgcga ggcccgtccc ttggtacgcc cctccaaata gctgccaagg
    57121 gtaatcaagg tcagaataac cacaacagat tcaaaataaa gctggtgagc aaattgagca
    57181 gctccagcta caatcttaaa acagctatat gagctgtaaa taaaagcaaa gctagtggct
    57241 aaggtcacaa gcgaatccat attaggccgc ttctttatca atgccttaaa gccattttca
    57301 tagtactgcc gattcaagaa aagaacaggc agggtcagca aaagctgaac aagaccatag
    57361 cttatagcat gcgactgagg tgctagagcg accggcagca ccaatccaag cataggtccc
    57421 attgcaaggt atagcagcgg cagactaaag agagcagacc acagaaagcg ataccattca
    57481 ttgctagcct gctcctctag gcgctctagt tgccctctca tattggtctc atcaagcagc
    57541 tctgctctgt agcctgcctt tcttactgct tgaatgagct ctgctgagct gaggctgtca
    57601 gttgagtagc tcactgatag cttctcagtc gtcacatcaa cagctgcccc ctcaacacct
    57661 ggcagttgct taacagcctg ttcaatcgct agagcacagg aggtgcagtg cattccctct
    57721 aatagatagg tctctttaac aatcatatcc tctccttttt ctgacaatga cattgtcctg
    57781 gcacacaatc acaccttaca tgggatactg ctccgacttt tttagcctct aagagcaact
    57841 gaaaagcctg aatatcttcc agggtcattg gggtatcctt tagtaatgcc agcaacaagc
    57901 ggctatggtg gcgttgacac atgccatcaa gcctctctcg tagcatagca agctgtcgcc
    57961 tgtcctgatc aagcaaggac tggtaaatat aggaccgtcc ctgtctatca gcccttaggg
    58021 cttttttctt aaccaagcgt ccaatcaagg tcttaacggt agaatcagac caatggtgct
    58081 tttcatgaag aatagcaata atctcagagc tcttcatgct cccattagcc caaacaacac
    58141 gcataacctc ccattctgca tcagatatcg tatccatatt gctacctctc tttcatctac
    58201 ggttttatta agtatagctt atttgtttac gtttgtaaac aaataataac taaaaaaggt
    58261 ctctttatga gaaacagcgt caaaaaagga ctgacagcta aagtcagcag ctagctttta
    58321 atagtctgaa ctttccagtc ttatctgatt aactttatat tgacaaaatg agtccttgta
    58381 tattactata tgacagtaat actgtaatga ttaaggagaa aacattgacg tatcttaaaa
    58441 gacagctaat tctactagcc cttctactca cagctatagg tagccaaaca atcgttcagg
    58501 ccagcacgcg atcctggaaa agctggttta ttgagcaata tttttggctt aaacgagaca
    58561 aaagctatta tgccgagcag gatgagaata ccttctacaa ctacgtcaag tcagctggtg
    58621 aaaagagcaa tcaaggcttt aatctcactc aaaatgaggt caacggaaca ttaaagacag
    58681 agtatagaga caacatgcag gttcacagct ggaatgaaaa ctctactaat ccatcaaatc
    58741 aaaaggtcat tctctatctg catggtggct cctacctaaa caacccgacc tcataccata
    58801 ttgacatgct caaaaccttg tcaactagcc ttgatgctaa gattgtattg ccgatttacc
    58861 caaaggctcc gacctatacc tatgatgtcg ctatgccaag attagttagt ctttatcagg
    58921 atattctaaa aagcactaat aacaatgcta acaatatcac catcatggga gactcagccg
    58981 gaggcggtct ggcactaggt ttggcactag cattgaaaaa tgaagatatt aagcagccta
    59041 aggacattat cctgctctca ccttggcttg atgtcaccct atcaaatcca gagatcccaa
    59101 attacgaagc ctctgatcct atcttatcgg cttggggact gcgcatagta ggtgatatct
    59161 gggcacgacg cggggaaaat aacactaagc acccttatgt tagccctatc tatggagata
    59221 caagcaacct agcacctatc accatgtttg taggaactca tgaaatcttc tacccagaca
    59281 ttacaaaatt tgatggtatg ttaaaacaaa aaggacataa gcaccagcta tttgtcgggg
    59341 aaaagatgaa ccatgtttat cctatttacc cgattgaaga ggccaagaca gcacaatacc
    59401 aaatcattga taccataaaa aaagagtacg aaccccaaaa ataataatac aaaaatgcct
    59461 accagacttg agttttttgc caaagcctgg taggcatttt ctgatcacag catgactact
    59521 gtttcttttc tagctcacgg agcaattgat caattttatt accataggcg atagaattgt
    59581 ccttttcaaa aaccaaatcc ggaattttat acatggttaa ttgcttacca agctcacgct
    59641 taatggttcc tgttgctttt tttaagccta tttcagcctt ttgattgtct gaagctaggt
    59701 cactcataat ggtatagtaa accttagcaa ctgacaaatc gcccagcatt tgcacttctg
    59761 tgatcgtaac accctgcaca cgtggatcac gaaccttttt gtgtaaaatc tcgttgacct
    59821 cacgcttgat ttccatacca acacgatcaa tacgatgatt tgtcatggcc cttcctttct
    59881 attgtcaaat agtacaggct ctcagtagct caataacaag agaaaagctt gatgactttc
    59941 aagccttttt ctctattagg ctgatggcta tactattaat agtgactgtt caaatcaagt
    60001 ggtgacattg tctattgtct tgagacgagg ctatttaagc tactagccac cacgattatt
    60061 tacgggtaat ttcttccatg acgtaagcct caatggtatc atcgacctta atgtcattaa
    60121 agccttcaat catcaaacca ccctcttggg cattcccaat ctccttaaca tcgtccttat
    60181 aatgcttaag actggctagc ttaccatcaa agataaccac gctatcacga atgacacgta
    60241 cacttgaatc acgcgttacc ttaccattaa caaccataaa gcctccgatt gtcccaacct
    60301 tagagacctt aaaggtttca cgaataatag cctcaccaag cattttttct tgatactcag
    60361 ggtcaagctt acctttcatg gcttcctcaa cctcttcgat caccttataa ataatgctat
    60421 gcaagcgaat ctcaacatcg tctgtatcag cctgctgacg cgcctgtggt gttggacgca
    60481 cattgaagcc tatgataaca gcgtttgaag cctctgccaa ggtcacatct gactcattga
    60541 tcgcaccgac agcagagtga acaacattta ctcgaacgcc ctcaacatca attttaagga
    60601 gtgaggctgc caaagcttcc acagagccct gcacgtctgc cttgatgatc acgttaacgg
    60661 ttttgatttc ccctgccttg agggtatcaa ataggttatc aaggctgaca cgctgcgtgt
    60721 tttgacgttg cttgagaagg gcacgcttag cacgctcctc ccctgctgca cgcgctgctt
    60781 tttcatcagc atagaccgca aaatgatcac ccgccatagg ggtttcattg agaccagtaa
    60841 tagataccgg tgtggacggc tcagctgatt tcacacgacg accaaggtca tttgtcatgg
    60901 cacgcacacg accaaaggtg ttaccaacaa cgattgggtc ttgtacgtgt agggttcctt
    60961 gttggaccag aagtgtcgca accgcaccct tacctttgtc aagtctagcc tcaatgaccg
    61021 taccaatcgc acgaaccgta ggatcagcct ttagctcttc aacctcagct accaaaagca
    61081 ctgtttctag cagctcatca atgtttttgt taaatttggc agagatttca acaaactcac
    61141 actcaccacc ccaagcagtt gagatgatcc catgctcagc caattctgaa ataacacgct
    61201 caggattagc ccctggcttg tcaatcttgt tgatggcaac gataattgga acaccagccg
    61261 ccttagaatg gttaatagct tcaatggttt gtggcattac cccgtcatca gcagctacaa
    61321 tcaaaatggt aatatctgtc actgacgctc cacgtgcacg catgcttgtg aaggcagcat
    61381 gtcctggtgt atccaagaag gtaatcttct tgcctgcctc ctcaatctgg taagctccaa
    61441 tatgctgggt gatccctcct gcttctcctg ttgcaacacg agaatttcta agggtatcaa
    61501 gcagggtcgt cttaccatga tcgacgtgtc ccataatggt aacaaccggt gcacgctcaa
    61561 caatattctc aggattaagg tagctatcat cagtaaagaa gcgctcgata tcagcttcat
    61621 caacctccac cttggcctta gcttcaatgc cataatccac cattaagagc tcaatggtat
    61681 caccatctaa ggattggttt tgcgttgcca tcacacccat cataaataat ttcttgacaa
    61741 tctcagccgg ctcacgcttg atccgttttg caatttcagc aacggtcatt ccttctgaat
    61801 attcaaattc ttttggtaat tcatggaatt tacgctctgt tactggtttt ggagctgtgt
    61861 tgctattctt atgatgctta ccttttttgt ttttcttgtt gttattccag ttactattct
    61921 tttgatttct cacttggttt tgactattcc aactcttctt atttttcttt tgtccatctt
    61981 ctaggccatg atcccgatca tgccctttgt ctggacgatt ttgtttttta cgacgcttat
    62041 caaccggttt tgctaccgat gcagcagcca tactagcaac cgactcagta gccttagctg
    62101 aggcttcacg atgctttttg tcctctgtct gagccttgag ggcggctgcc ttagcctctt
    62161 gccttgcctg ttgctctaag cgtttagcct cctcttgctc acgaaagcgt gattcccttt
    62221 gtctggcata ctctgcgttt tgctcagcct ttaaggcagc agcacgcgcc ttaaaatcaa
    62281 tcttaggagc accggcttgg gtctgccctt gacgtcctgt atcctgttga cgactattag
    62341 cgttaaagga acggtttttg tcacgattac cagcttgtct atgcccatcg tttcggttat
    62401 ttccagatga tggcctgtta tcaaagcgtc tatctctttg ctgattttgt gacttgtggc
    62461 cagctcgctc cgtctgctga ccttgtgatc gtccaagttg acgatagtct gacttgcggt
    62521 cattagagcg attttgccca gcctgccgtc tcgctacctg ctccttggca cgtgcttcac
    62581 gctctgcctt gaaattgcgg ctctttggct taacagcaac cggctgtgat gcttcttgtg
    62641 tcgcagcagc tggcttttct gctgctttag aggctgctgg ctgtggtgta gtggccttag
    62701 ctgcttttgc tttttgttct gctacttgct tgtcttttgc tgaacctgct tgaacattct
    62761 tagtcacacc tgctgaaaag ctagaggcaa ttttgttagc atctgcttct tcgacgcttg
    62821 acgcatggct tttgacatct aatcctaagg atttagcacg ctcaacgact tctttactac
    62881 ttttgccaat ttccttggca atttcatgta atcttttctt tgacaatttg tgtcctccta
    62941 ttcgtctatt tcataagagt cctcattttc tttgaaaatc cagcgtctgc aatggcaacc
    63001 accttacgag gcttgccaag tgcagcactt aattccagtg cactaaacac tgtggagact
    63061 tctacattgt aataattact tttatctgtt acttttttag tgatatttgg gccagcatca
    63121 ttggctaaaa aaacaagatt gacttcctga tgtcgaatgg ctttaatgac caattcctca
    63181 cctgaaatca cttttttggc ccgctgagcc agtccgatca aatgagataa tctatttaaa
    63241 ctattcaagg cctagctctc ttcttttaac tttgtgatca acatgtgcaa tcacttcatc
    63301 gtaaaagctc tctggcacct ccattgagaa gctacgatta aacacctgtt ttttctttgc
    63361 cataagtgct tcttggttat ctagcttgat ataagcacca cgcccatttt gcttgccggt
    63421 tggatcaata aaaatctgcc cctccttatt tttgacaata cgaaggaggt cacgcttatc
    63481 aatgatctca ccagaaacaa gcgacttacg taaaggtatt ttttttactt taggcataaa
    63541 acacctcttt tcttacactt cctcgttggt taagagctcc tctgtagcta ctgcttcagt
    63601 cattgctgct tctttttctg cttcaaggcg ttcatattca ctggctgatt tgatgtcaat
    63661 gcgatagcct gtcaaatgag ctgccaaacg aacgttttga ccacgacgac caatagcaag
    63721 cgatagctta ttatcaggca ccaccacagt cgcacgctta agatcgtcat catcaaagag
    63781 aaccatatca acctcagcag gtgcaatggc attgtagata aattcagcag ggtcatctac
    63841 ccattggata acgtcaatat tttcttctac tgggatctca agtcctgtct tagcatcata
    63901 gcgctttgga tggaatttac tgataacctt tttgatgttg ctgccgccac gaccaacaat
    63961 cgttccaatc gcatcaacat tgggattgtg gctacgcaca gcaaccttag tacggtcacc
    64021 agcctcacga gaaacactca taatctcaac ggtcccatca aaaacctctg gaatttcctg
    64081 ttccataatg cgcttgatga actcagggtg actacgacta acaaagacgt taaccccctt
    64141 tggattgttt tccaccttgt agacatagac atcaatccga tcatgtgatt tgaaggtttc
    64201 tcctgggatt tgatcctgat gtgagagctg agcctctaag gaaccaaggt taacataaat
    64261 gaaacgttgg tcaaaacgct caaccgtacc cgtcatgatt tcaccttcat gctgcttgta
    64321 ctcattgaag gtgatttctc gcatctgacg acgcatcctt tccataatgg tttgctttgc
    64381 agattgagca gccacacgtc caaactcgct gactgattct tcaaaacgaa tcttatctcc
    64441 taactcatag gctgagctaa tggcaagggc atcgttcagg ctaatttcca gacggctatc
    64501 aaatacctct tcaacaacct cacgaaccgt aaaaacctga aaatctgctg ttttatcatt
    64561 aaattcaatg acgcaggatt ctgcttgacc ataacgacgt ttataagctg atttcagtga
    64621 ttcagtgact gcctcaatga tatctgcctt atcaatgtgt ttttcttctt ccaaaatacg
    64681 gaaggcttct agcatttctt tgctcataat gttgtctacc ttgctctcaa agcttggtaa
    64741 aaatcctttc ttatcttata aattaatcca tttagggctt agccaaccga ctaaagcaaa
    64801 tcgctcagca attgccttat aatttgacag ctaaacgagc cttagccact gcttggtaag
    64861 gaatctcaac tgttttgtga cgcgtcttat ctagataatc aatggttagg gtatcaccat
    64921 caaaagccac taaatctcct tgaaaaacct tcaccttatc aattgcccga tagaggctga
    64981 cattaatata tgagcctaca gcagccttca agctctcagc agtctttaat ggacgctcta
    65041 gcccaggact ggaaacctcc agcatatact gatctgggaa agggtctgga gaaatcgtat
    65101 ctaagagtgg actgattagc tctgtaagct cagcagtatc ctcaacggta atcccagaag
    65161 ccttatcaac taagatacta aggacataat cattgcccat tttgtcgtat tcgatgtcga
    65221 ccaattcata gggtgcttta attacaggtt ctacgatttg ggtaacaata tcaataatag
    65281 ctgtgtttgc gatgttaata acctccttta ctgatgactg ctatacctct atagccttgt
    65341 cctcttgata atcaacacaa aagtggcgag atatttctca ccacccttct gtattgcttt
    65401 aacctattat accacaatca aaatgaattg caagaaaatc cctactaaaa gtgtcaataa
    65461 gacctcaaaa atcctatttt ttaaaaggag aggagatctt taaccttgct tttttctctt
    65521 tccttatccc ctctaacctc tgtattcata tgataaaata aaatattaaa gggtaaaaaa
    65581 gacaactaaa atattatttg cggctgcttc atggtcttta ccaaaacgaa aaaacctccc
    65641 atcagaacag atctatgcat atgcgagaga ggccattggt aactcaataa catcattaat
    65701 aaagcttaaa ttagttcaat ttgtaatttt aataccacta tttatcggta atataagttt
    65761 atctgaggat attaaaaata ttaatgctat ttttaaagac agcattagtt aatgatataa
    65821 taaaagctgt aatctccctc attatatcat aaaaacgatt tcaaaaacag acttgtattt
    65881 caagtgacat ttgatatact tgaagatggg aatactgctt gagtggaggc attgtaggtc
    65941 tagttcaacg taaagcagca gctgaaatcg caaaactaat acttaaagtg gggatcaaga
    66001 atgtagcccc tgctgcagct gcagcatcat taatttggag ctttggaaga tgcatgtggt
    66061 tttaatgtca aaaagatata gtatttgtat aacatttctt gttattattt cgcgattcgt
    66121 ttggtttgcc cttacaggaa gaagtccttt ttatgacttt attgggacta tatttttagg
    66181 agtagtggtt ttactaatta gtcaaaaagt attgaaaaaa ttaaagtgat aaaattatta
    66241 acccgacaat agcgaagcag aatgtgatat tattgatatg ttccataaga tactttctaa
    66301 tgagattgtt agtgcttctc atgataagtc ttatgggact tttttgtact caaaaagccc
    66361 tatcatttcc atactggata aatccactac agaaatgata gagcctaaaa tatatgttca
    66421 ccaattggat aagttaaaag aaaaaaatga ccatcaggtc aaaagcattt ttcaaaatct
    66481 caaatttgac gggtgaaaaa caggcgaaga ctccgaaacc cttgatatac caataggata
    66541 aaaggagagg aggggattgc tggtagctat ctcaccgttt tcatcctttg tagaacactt
    66601 gaacgttggt gttttgaaaa tataaaaagg atagaaaaag atgaaaaaac aaaaataaac
    66661 gggtgattga cgggtaatgt tactccaatt ccatcagcac ttcttctact ttttcgtctg
    66721 tcacaacttc tccattcttt actttctcat gtggcaacac ataatcaaaa atctgtccgt
    66781 ttttgcgcac gatcgtgact gtgtcttcta cgatatatcc acggtcaata gcttgcttaa
    66841 attcgtcgta tgttagcata aagcacctcc tacttatcta ttcgtaaaaa agccaaatct
    66901 agtgagaaaa gatttggcat gtttattatt gatttgcaga gaatgtccct tggttgtagt
    66961 ctattgtata cccattagct acattatata caattacttt ttcgttaatc gtgttatctg
    67021 aagatagtac agacaccact accgctcttg gtaccaactc attgccttgg tatattggca
    67081 ttgcttcata gtaaaggtaa ccgtcacgat gggcttctag ccacttctga gatttaattt
    67141 ctgtatatct catccctcca ttgccagaac gacctccaac attttgtgtt cttgttcctg
    67201 taatagcatt tactctaagg gcatctccgc ctagactatc tgcaattaaa tgactcttat
    67261 tccaaaaata accttgataa gaatcatcac ctaacccctt tataacatag acttccccat
    67321 ttttatttcc taaccatcct gacaatgttt ctgctttact acgtttaaaa tcttttctta
    67381 tattgtaact acctaacaca ttattgaagg tcaaagttcc tctaactgtt aatgttctgc
    67441 caagactgtc aagaccacca tagactattt ggccttttgg tggaaataaa ttttctacta
    67501 ttccactttc tcctaatact ttataataat ttggggaagt ttctaatgtc cacgacaaag
    67561 cttcaggtag atatgtatct gaggagttat agctattagc aacattaact tctttagtat
    67621 cagctaaagt agcctgttga tatgataatg atataggaga tgatattaga agaattagaa
    67681 atatgctaga aataaattta cgtaatctta tgttgttcat tgttcgacct ctttttttta
    67741 tttttttatt ctcactaatt acattatatg tttacttgat tggttaatca aatctttttt
    67801 taacattttt gaaatttaac cgatcgtatt aatatgttta cattagtatt tctaagtaaa
    67861 cgttgttttc aaaattaaaa caagtttaac tataattagc atctaataaa aaaacagccc
    67921 ccgcaaaagc gagggcgttt gtcttatcta atttaattta ccccaaaggc tgatgcgatt
    67981 gccatcttta tctgtctgtc caatagctag gtagttacgc ttgcctgagt cgccaacata
    68041 gctaatccag tagtagccat tagcgtagcc ctcgctatca aaactgacag tatcatcttg
    68101 tttgtagcta cctactactt cactcgctag gcttggccaa cgtctgatat tgatttctgc
    68161 gacatctacg gtaaaagtac ctgtttttgg tgtctctacg atagtgtcag acgtttgcgg
    68221 tgctgtatct actgtctgct tagtgtgatc aaccggtaat ctaatccagc cgacaacacc
    68281 agtaaagtca cgagtattaa agcgagcggg accacctacc tgaagactat cccagttacc
    68341 gtcaatattt tgctcaacgg ttttaatagt atagccatca ctgtcctcaa taacagctcc
    68401 cgtgtgtccg tagggactac cagctacctc catgacaaat aagtcaccag ctctaggatt
    68461 gactccggga gcattatata tgatctctag cccttgcgca gatgcactat ttaacaggtc
    68521 aatcgcatta ccccataaat caatgccgaa ccagtttttg acgataaaac atggcaagtc
    68581 cgcacactgc gtcccaaaac agccatcttt atcaacaccc atgcctgaat tggctaggtc
    68641 gacacagtat tgtacaatct catttgcggt tgtcatcgtt acctccttat tagtttttaa
    68701 ggcttcttcg tcccacttct gcagatcgtt ctcctcgatg atctggataa gcagctccgc
    68761 atatccactt gcagtcgcat accctgcagc cttaat
//
LOCUS       DARYXZ010000002        61518 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYXZ010000002 DARYXZ010000000
VERSION     DARYXZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61518
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..485
                     /locus_tag="TV186_000060"
     CDS             <1..485
                     /locus_tag="TV186_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1531503.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
     gene            complement(588..1430)
                     /locus_tag="TV186_000061"
     CDS             complement(588..1430)
                     /locus_tag="TV186_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL1531504.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(1847..3727)
                     /locus_tag="TV186_000062"
     CDS             complement(1847..3727)
                     /locus_tag="TV186_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1531505.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAETKARTAEEEAKQATADKE
                     KAETEAKKAKEEAKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDLETQKEKL
                     EQEIKEATEAKNKAEQKLKDLQDSASQGSELSKQLLKEKEELTTKLQELQKQAEEKTT
                     EIEKLKQELEANKQNSGQLGQQEQKLQEQLNKVQKELKQKEMELKQAQEQLKQEQKPH
                     EGGGDSDASKARITELEKQVQTLTKEKADLSSTLESTKAQLSETQARLSEAQKQLTAA
                     QEKLTTLEAEKTALQHQVETISKQLSETRDLSEKEKAALQEQINKLKAEIEQKTKEIE
                     ALKQGMQSHQGQEKPKDPKTPETPKDPKTPEKNDQPQAPEKRSVPWTALTPAKPIDTT
                     KAPKSSAPSPQTGAATPKKQLPATGDTATPSFFTAAAMAVLASVGVLNLSPRRKKNQN
                     NR"
     gene            4132..4776
                     /locus_tag="TV186_000063"
     CDS             4132..4776
                     /locus_tag="TV186_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531506.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            4781..5530
                     /locus_tag="TV186_000064"
     CDS             4781..5530
                     /locus_tag="TV186_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1531507.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(5635..5784)
                     /gene="rpmG"
                     /locus_tag="TV186_000065"
     CDS             complement(5635..5784)
                     /gene="rpmG"
                     /locus_tag="TV186_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1531508.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(5800..5982)
                     /gene="rpmF"
                     /locus_tag="TV186_000066"
     CDS             complement(5800..5982)
                     /gene="rpmF"
                     /locus_tag="TV186_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL1531509.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            6252..7082
                     /locus_tag="TV186_000067"
     CDS             6252..7082
                     /locus_tag="TV186_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531510.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            7142..8422
                     /locus_tag="TV186_000068"
     CDS             7142..8422
                     /locus_tag="TV186_000068"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL1531511.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(8627..9919)
                     /locus_tag="TV186_000069"
     CDS             complement(8627..9919)
                     /locus_tag="TV186_000069"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1531512.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(9909..10625)
                     /locus_tag="TV186_000070"
     CDS             complement(9909..10625)
                     /locus_tag="TV186_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1531513.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            10879..11103
                     /locus_tag="TV186_000071"
     CDS             10879..11103
                     /locus_tag="TV186_000071"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531514.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            11114..12034
                     /locus_tag="TV186_000072"
     CDS             11114..12034
                     /locus_tag="TV186_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1531515.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            12021..12761
                     /locus_tag="TV186_000073"
     CDS             12021..12761
                     /locus_tag="TV186_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531516.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            12918..14666
                     /gene="aspS"
                     /locus_tag="TV186_000074"
     CDS             12918..14666
                     /gene="aspS"
                     /locus_tag="TV186_000074"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL1531517.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            14659..15606
                     /locus_tag="TV186_000075"
     CDS             14659..15606
                     /locus_tag="TV186_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1531518.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            15622..16503
                     /locus_tag="TV186_000076"
     CDS             15622..16503
                     /locus_tag="TV186_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1531519.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            16647..17561
                     /locus_tag="TV186_000077"
     CDS             16647..17561
                     /locus_tag="TV186_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1531520.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            17733..19127
                     /locus_tag="TV186_000078"
     CDS             17733..19127
                     /locus_tag="TV186_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1531521.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(19175..20866)
                     /locus_tag="TV186_000079"
     CDS             complement(19175..20866)
                     /locus_tag="TV186_000079"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL1531522.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            21143..21580
                     /gene="argR"
                     /locus_tag="TV186_000080"
     CDS             21143..21580
                     /gene="argR"
                     /locus_tag="TV186_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1531523.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            21582..21932
                     /locus_tag="TV186_000081"
     CDS             21582..21932
                     /locus_tag="TV186_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1531524.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            21919..24474
                     /gene="mutS"
                     /locus_tag="TV186_000082"
     CDS             21919..24474
                     /gene="mutS"
                     /locus_tag="TV186_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL1531525.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            24621..26603
                     /gene="mutL"
                     /locus_tag="TV186_000083"
     CDS             24621..26603
                     /gene="mutL"
                     /locus_tag="TV186_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL1531526.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            26614..27837
                     /locus_tag="TV186_000084"
     CDS             26614..27837
                     /locus_tag="TV186_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1531527.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            27839..28435
                     /gene="ruvA"
                     /locus_tag="TV186_000085"
     CDS             27839..28435
                     /gene="ruvA"
                     /locus_tag="TV186_000085"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL1531528.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            28445..28996
                     /locus_tag="TV186_000086"
     CDS             28445..28996
                     /locus_tag="TV186_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL1531529.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(29432..30277)
                     /locus_tag="TV186_000087"
     CDS             complement(29432..30277)
                     /locus_tag="TV186_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1531530.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            30574..31146
                     /locus_tag="TV186_000088"
     CDS             30574..31146
                     /locus_tag="TV186_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1531531.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            31140..31430
                     /locus_tag="TV186_000089"
     CDS             31140..31430
                     /locus_tag="TV186_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531532.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
     gene            32116..33387
                     /locus_tag="TV186_000090"
     CDS             32116..33387
                     /locus_tag="TV186_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL1531533.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            33481..34617
                     /gene="recA"
                     /locus_tag="TV186_000091"
     CDS             33481..34617
                     /gene="recA"
                     /locus_tag="TV186_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL1531534.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            34993..35391
                     /gene="spx"
                     /locus_tag="TV186_000092"
     CDS             34993..35391
                     /gene="spx"
                     /locus_tag="TV186_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL1531535.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            35504..35773
                     /locus_tag="TV186_000093"
     CDS             35504..35773
                     /locus_tag="TV186_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL1531536.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            35770..36189
                     /gene="ruvX"
                     /locus_tag="TV186_000094"
     CDS             35770..36189
                     /gene="ruvX"
                     /locus_tag="TV186_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL1531537.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            36199..36498
                     /locus_tag="TV186_000095"
     CDS             36199..36498
                     /locus_tag="TV186_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL1531538.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            37046..38605
                     /locus_tag="TV186_000096"
     CDS             37046..38605
                     /locus_tag="TV186_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL1531539.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            38702..40900
                     /gene="nrdD"
                     /locus_tag="TV186_000097"
     CDS             38702..40900
                     /gene="nrdD"
                     /locus_tag="TV186_000097"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL1531540.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            41006..41152
                     /locus_tag="TV186_000098"
     CDS             41006..41152
                     /locus_tag="TV186_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531541.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            41180..42115
                     /locus_tag="TV186_000099"
     CDS             41180..42115
                     /locus_tag="TV186_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1531542.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            42128..42622
                     /locus_tag="TV186_000100"
     CDS             42128..42622
                     /locus_tag="TV186_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1531543.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            42632..43246
                     /gene="nrdG"
                     /locus_tag="TV186_000101"
     CDS             42632..43246
                     /gene="nrdG"
                     /locus_tag="TV186_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL1531544.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(43704..44435)
                     /gene="yaaA"
                     /locus_tag="TV186_000102"
     CDS             complement(43704..44435)
                     /gene="yaaA"
                     /locus_tag="TV186_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL1531545.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            44871..45074
                     /locus_tag="TV186_000103"
     CDS             44871..45074
                     /locus_tag="TV186_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1531546.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            45076..45529
                     /locus_tag="TV186_000104"
                     /pseudo
     CDS             45076..45529
                     /locus_tag="TV186_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            45539..46213
                     /locus_tag="TV186_000105"
     CDS             45539..46213
                     /locus_tag="TV186_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1531547.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            46243..46680
                     /locus_tag="TV186_000106"
     CDS             46243..46680
                     /locus_tag="TV186_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531548.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(46903..47676)
                     /locus_tag="TV186_000107"
     CDS             complement(46903..47676)
                     /locus_tag="TV186_000107"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL1531549.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(47760..48827)
                     /gene="pepA"
                     /locus_tag="TV186_000108"
     CDS             complement(47760..48827)
                     /gene="pepA"
                     /locus_tag="TV186_000108"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL1531550.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPGHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            49172..49519
                     /locus_tag="TV186_000109"
     CDS             49172..49519
                     /locus_tag="TV186_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL1531551.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            49516..49833
                     /locus_tag="TV186_000110"
     CDS             49516..49833
                     /locus_tag="TV186_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL1531552.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            49848..50474
                     /locus_tag="TV186_000111"
     CDS             49848..50474
                     /locus_tag="TV186_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL1531553.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(50777..51490)
                     /locus_tag="TV186_000112"
     CDS             complement(50777..51490)
                     /locus_tag="TV186_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1531554.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            51602..51997
                     /locus_tag="TV186_000113"
     CDS             51602..51997
                     /locus_tag="TV186_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1531555.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            52444..53418
                     /locus_tag="TV186_000114"
     CDS             52444..53418
                     /locus_tag="TV186_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1531556.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            53436..54398
                     /locus_tag="TV186_000115"
     CDS             53436..54398
                     /locus_tag="TV186_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1531557.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            54513..55397
                     /locus_tag="TV186_000116"
     CDS             54513..55397
                     /locus_tag="TV186_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531558.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICATGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            55406..56209
                     /locus_tag="TV186_000117"
     CDS             55406..56209
                     /locus_tag="TV186_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1531559.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(56308..57312)
                     /locus_tag="TV186_000118"
     CDS             complement(56308..57312)
                     /locus_tag="TV186_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531560.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(57598..58239)
                     /locus_tag="TV186_000119"
                     /pseudo
     CDS             complement(57598..58239)
                     /locus_tag="TV186_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(58260..59237)
                     /gene="dusB"
                     /locus_tag="TV186_000120"
     CDS             complement(58260..59237)
                     /gene="dusB"
                     /locus_tag="TV186_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL1531561.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(59224..60096)
                     /gene="hslO"
                     /locus_tag="TV186_000121"
     CDS             complement(59224..60096)
                     /gene="hslO"
                     /locus_tag="TV186_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL1531562.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(60346..>61518)
                     /locus_tag="TV186_000122"
     CDS             complement(60346..>61518)
                     /locus_tag="TV186_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL1531563.1"
                     /translation="HNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNTE
                     LTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELVG
                     YISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLEL
                     ENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLSI
                     IYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTNK
                     SVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYILK
                     EKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT        17598 a        10909 c        13889 g        19122 t
ORIGIN      
        1 cattcaagcc aggggaggtt tcttttccta gtgggcgcgt ggaggagggt gagacttatc
       61 agcaggcggc tattcgtgag acggtagagg agctcaatat agagcctgag caggttcatg
      121 tttgggggga gattgactat ttagttcagc cgactcgtag cattcattgc tttgttgcgg
      181 aactggctat tgatgattgg agaaggctta gggtcaatga agaggttgat agcttgttta
      241 cggtgccttt ggaggagctc atggcgcaag ctcctgttgc ttatccttta caaatgcaat
      301 cgataatctc gtcagacttt ccgttggatc gtatccctaa tggagagcag tacaggttga
      361 ggtacatgca agatcaggta ttactctatg agcatttaga aaagcctatc tggggtataa
      421 ctgctcaatt gacgaaccgt tttatagaaa tcgtgacaga ggcaagacag catgatgaca
      481 tataaaaaaa cgaatgctag tcacagctgg tgataaggct gagagctagt cattcgtttt
      541 tttgatctta atgctgctgt tagaggtact tgctggtgta tcgagtgtta tttgtatttc
      601 tcctcaagct ggctcatcca tagaccaagc cagacaccaa ggccaaataa tagcagagcc
      661 attagccagg tgccaagacc tgcaccggcg taagagatag cttccttatt actgctattt
      721 ggaattaaaa taagcagggt gctggatagg acgataccga taataaagtg gtaaacgcgt
      781 gaatggtagt gcttgagagc aaaatccata atcttggaaa aagctagcat ggttaataag
      841 ccaccaatag caatgggtaa aaaggttcct accaaatcaa gtgatttaaa gccaatcagc
      901 atgggtgagt aaagtcctaa aattaataaa agattagacg ggctaagacc aggtaccaaa
      961 atacctaaag caatcaaggc accagctagg acaaaggcgg taaagcttgc aggtattgtc
     1021 ccaacgagat catttaagaa ataaagtccc agtcctgata ggacaaaggt taatactagc
     1081 cagagccaat caacttggtc acgctgagat gtttttgtcg aagtctttat caggctaggt
     1141 acggttccta tgatggcccc agcgaagccc cataagactg gtacctgata gtgcttgagc
     1201 agatagtcaa cagggtaaga aaagagggca atccctaaaa taccaccaac cccaacaggc
     1261 aggaaaaaga gaacattctc aacaaaatgc tcacgtatat gagctaaaaa ggcaatgata
     1321 cgctcataga tcccaaggat agcggctaat actcctccag atactcccgg taaaataaag
     1381 ccaagcgcaa taattattcc cttaatcact cgtgaaagaa ctgaaaccat acatgcctcc
     1441 taaaaatcgt acccctattg taccatattt ttaatagctg tatttacttt tcatatctgt
     1501 aagagctatc gtgactatag gaacaactcg cagttttgta tgatttatct ttgttgatcc
     1561 atttatatag agcatcgaag ctaccaaaag tgatgattag gcaccttctt gcgtaagcta
     1621 aagtgggtat gggagaaaag agtaggttta aaatggagga caaggtaggt ttgaccttgg
     1681 tgtgtttcac aatcacaaaa cgagtcaagc caataggcag gacagcctgt ttagcttgac
     1741 tcaaaggctt tggttaaagt actaatgtca gtgatttttg gttagacatt tgtttttgct
     1801 catgtcgggt ttgctgttat tcaatccaga tatgagagtc tctacattaa cggttgtttt
     1861 gattcttttt gcgtctaggt gagagattta ggacaccgac gctagccaat actgccatag
     1921 cagcagcggt aaagaagcta ggtgtcgctg tatcaccagt tgctggtaat tgttttttag
     1981 gtgttgctgc cccagtctgt gggcttggtg ctgagctctt aggagctttg gtagtgtcaa
     2041 ttggcttagc tggtgtaaga gcagtccaag ggacactacg tttttcaggc gcttgtggct
     2101 gatcgttttt ctcaggagtc tttggatcct ttggtgtttc cggagttttt ggatcctttg
     2161 gtttttcttg accttgatgt gattgcatgc cttgctttaa ggcttcaatt tccttggtct
     2221 tttgctcaat ctcagccttt agcttattga tttgctcttg gagtgctgct ttttcctttt
     2281 cgctaaggtc acgtgtttct gatagctgtt ttgaaatggt ctcaacttga tgttgaagcg
     2341 ctgttttctc ggcttcaagt gttgttaact tttcttgagc agcagtcaat tgtttttgag
     2401 cttctgatag tcttgcttga gtctctgaca attgagcttt tgttgactca agggttgatg
     2461 acagatctgc cttttccttg gttagtgttt gaacttgttt ttctagctca gtgattcttg
     2521 ctttggaagc gtcagaatct ccgccacctt cgtgaggttt ttgttcttgt ttcagctgtt
     2581 cttgagcttg ttttaactcc atttcctttt gtttcagctc tttttgaacc ttattcaatt
     2641 gctcttgaag cttttgttcc tgttgaccta gctgaccact gttttgttta ttagcttcaa
     2701 gctcttgttt tagcttttca atttcagttg ttttttcctc agcttgtttt tgaagctctt
     2761 gaagttttgt tgttaattct tctttttctt ttaacagctg tttagacaat tcactgcctt
     2821 gactagctga atcttgtagg tcttttaatt tttgctcggc tttgttttta gcttctgtag
     2881 cttctttaat ctcttgttca agtttttctt tttgagtttc taaatctttt ttagattttt
     2941 ctgccagatt agctctttgg ttagcctgtt gattagcttg ttctaattgt ttagcttttt
     3001 cttgttcttg atgagcagct tctttagcgg tcttagcttc ttctttcgct tttttagctt
     3061 cagtctctgc cttttcttta tcagccgtag cttgtttagc ttcttcttca gcggttctag
     3121 ccttagtttc cgcattcctt ttatcagcct ctgctttttc tttatcggtt ttagcttgtt
     3181 ggtaatcttc ctcaactttt cgagtttttt gtttttcagt gtctaataat ccctctagtt
     3241 tatgtaaatt ttcaattgtt actttgaaag cattcctagt tttttctaat tcactttctg
     3301 caatctgttt ctctatttta gctttagttt ctaatttttg agcttgctcc aaagctgaga
     3361 ctcttttttt tatttcatta acaactgcct ttctattatc atttttgttt ggattgttga
     3421 aatatgataa taatggtgtg attgggccat ttaatataaa actaaaactt tctggatcta
     3481 tatttacatc ggctgatata atagcaaata aagcaaacaa tgtattggga tcactaattt
     3541 gtcctaatac tgtttttaac ttaccactat ctgattgtaa aacttgctca atttttttta
     3601 cgtccgcact catatctcca tacacaactt tatttccaag tagtcctgtt cctatcaggc
     3661 ttcctgtgat gagagtagct gctagggctt gatgacacaa gcgtctgatg tttgattgtc
     3721 ttttcatgat ttagtcctca catatcgtcg aatgtttttt ctaaaattct tccaaaaaat
     3781 cttaacatga cgcttgcagg ctgtgaatac gttttgggca attcgcctcc gtagtttcgt
     3841 tttttttaat tcaatcatta aacgtctgat tttatcatga tataattgat cttgttcaag
     3901 gctgatcagg aaattcttga tgaagatgac agctttatat cggtgtttgg gaaaccataa
     3961 gattggcaag gctacgctgg gcttagctga cattgttgct tcaaaatgct ttcaggtgta
     4021 gaaatgttga caagtattct ttaaaaagat agactatagc tagtaggata gaggtatgca
     4081 caggtgacag atgtgatact tgtgtttttt gctatttttg gaggtttctg attgcctatt
     4141 gcagcttatc aatatgaaag tgttgttgag attattagtg aaatcaatcg attacactat
     4201 tcattttctt cgggtttagg agctcttcta tgctttaatt tgaaaaagag tgtcagttcg
     4261 gtagtcgtta acaatcgtat tgatagggag ttccaagagc tcatcgtttc ttataaagca
     4321 aggctaaata ggaatattag tcaagtctca agcatacgac atcagtttat aggcattaga
     4381 tggagaataa agcaagcaga atctattagt gagaagcttt tatactacat gagcgagaat
     4441 catgagtttg gaaggattcc cttaaataaa tgtttgaatg attttcttgg atttaggatc
     4501 ttggtcaata acttagaagt tgtttttgct gctttgcaaa atgataatcg agtgactaat
     4561 attgctaaat tgtatttaag aacagatggc gactataaag gtatccatct atattttaaa
     4621 aatggaaata atcggttttt tccatgggaa ttacagattt gggatccaga gcaatcacgc
     4681 ttaaatgagc tgtcacataa agagcataag caaaaacgac aatatatatc actaccccaa
     4741 cattattttg atgctaattt agaaaaggag gaataaccgc atgtatcagc attttatttt
     4801 agttgctagt tcatatgcaa gaggtgagag agttggcttt cacttagcga cagaaggtca
     4861 attggatcat gttgccattg aagaaaaaat gcagcggctg agtcatatca atagagatga
     4921 tgttggtgtg cattcttttg ttacagatag tgctgattgg caaagtgtca ttgagttaga
     4981 ttcctttttt gaggatatta tggtttgtca agacttcgat gaatttgaac aggttttaca
     5041 atccgactct aaaattagtg ctattgatgt tgctaaattt ttcttagcaa tgcgtccact
     5101 ctcacactta caattgcaaa agttagttta tcttgcttat aaaacatatc ttcttgccta
     5161 tggtgaatcc ttatttgatg aaaaaatagt tgcttttcaa tatggtcctg tagtagaaga
     5221 ggtgtatcac agctttaaaa aatatggttc tgaggtgata gatatcgatg atcatacaga
     5281 atatatttta aaagacatac atcttccgca agccttaggt agaatgctat tggtcgaaga
     5341 cgcaaagaag attgtgcctg tattattaga tgttgttaaa cagtatggag atttaacagg
     5401 aggagaattg gttaagctga cgcactctga aaagggacct tggcagacgg tttttcgtcc
     5461 acagttaaat tgtgagatca ctgatgaggt tattttagcc caaggcagat atgaaagatt
     5521 atcatcataa gtacctttgc ttattgtatt agctgagaat actcagttgt ctcatcaaaa
     5581 ccaaaacaaa aaagcctttg aaacgttgat ttcaagggct ttctgtatat cgtcttattt
     5641 tacctctgta aacacaacat gtttacgtag ttttggtgag tattttttca attgaaggcg
     5701 gtctggagtg ttacgtttgt tttttgaagt aaggtacaag cgttcaccag attctttgtg
     5761 ttcaagtgtg atatttacgc gcatggtatc tcccttctat tattcagctg cgttagcttt
     5821 agcgatttta tgtcctttgt agtatccctt aagtgagaca cgatgtgaac gtgagtaatc
     5881 tccagttgtt tcgtcaaatt ttactgatgg tgcagtcaat ttgtagtgtg tacgacgttt
     5941 gttcttttta gcttttgacg tgtgacgtgc aggaactgcc attttttcta tcctccgtta
     6001 aatgatcaag ggtctattaa aagattggtg acaaactggt gtgcatgatc ttatgctaac
     6061 ctatctgtct caaatctttg acccattgtt atctatttga tgttatggct ttcgccaact
     6121 ttagtatcat atcatatctt ctatgtaaag taaagttact tgacaaaaat tttattaaaa
     6181 agctctgcta ttctccaaaa atcctaaaaa atggtaaaat gagacaaagg tggttatttt
     6241 aggagattaa gatgtttgga aaattattaa gtctgttagg ctttgtcgtt gctttgactg
     6301 gttgtggtgt ttcacaggca gaaaaagaac gtgttgtaac agagtatagc cccattatta
     6361 ttaaaaaatt tcaaacctta ggataccaag ggaaaatcac tgtagacgac tatactaaga
     6421 tgattgagac aggtagtgag agactttatt ttacctacag cgaagaagta gacggtaagg
     6481 ttattagtct gaaggatagt atttcgattg ctacctataa atcacctgag gaagatttgg
     6541 ctgatgcaga agttgacatg ggaattaggg aagaagctat gtggcagcaa ccagctgtca
     6601 aagcgcaagc tgctcagatc aaacaactat ttagcgagtt ggagactgag gatttgaagc
     6661 ttatatccgt aacaggacaa agtgtccaga cgatttctga ttcagatgga gagctgatta
     6721 gggaagatgt tgtacgaggc aggaatgaat tatctcaaga tgcatctaat aatagagaag
     6781 ctgggctatc aataggtggc tattatcata ttgatgtttc aaagtatttg aaaaatcacg
     6841 tgttggaaat tcgtatagat tttgattggc gaatgtcaga agaggaacaa gacgatttgt
     6901 ctggccccag gttggatttt tctgatagaa taaaaagtct agactttacc tgcttgtggg
     6961 atggctacta taaagtgggg tttgacaggg tgagtagatc taatcgaagt ggagatattc
     7021 aagatatgat tgttttagat attcgaggcg gtaaattggt tcgtagcttt tctgtacttt
     7081 aacagattaa tgaagctatt ctatggtaaa atatataaat actagtaaaa gaggaaataa
     7141 aatgaagctt caaaaaccaa aaggaacaca ggacattttg cctgtggctg ctgctaagtg
     7201 gcaatatgtt gaaggtgttg cacgtgaaac ctttaagcaa taccattatg gtgaaatccg
     7261 aacacctatg tttgagcatt atgaggtcat tagccgatca gtaggtgata ccactgatat
     7321 tgtgaccaag gaaatgtatg acttctatga taagggcgac cgtcatatca cacttcgtcc
     7381 agaaggaaca gccccagttg ttcgttcgta tgtggaaaac aagctctttg cgccagaggt
     7441 tcaaaagcct gtcaagctgt attatattgg gtcaatgttt cgttatgagc gtccgcaggc
     7501 cggccgtttg cgtgaatttc accagattgg tgtagagtgc tttggctctg ccaatcctgc
     7561 cactgatgtt gagacgatcg ccatggctta tcacctcttt gaaaggcttg gtattaaaga
     7621 ggtgaccttg catttgaata gccttggaaa tgcagctagt cgcgcagcct atcgtcaggc
     7681 cttgattgat tacctatctc caatgcgtga gaccttgtcc aaggatagtc agcgccgttt
     7741 agatgaaaac cctctgcgcg tgcttgattc caaggaaaaa gaggataaga ttgcagtagc
     7801 aaatgcccca tctattcttg attatcttga cgaggagagt caggctcact ttgatgctgt
     7861 gcgcagcatg cttgaagtac ttgctattcc ttatgttatt gataccaata tggtgcgtgg
     7921 gcttgattat tacaaccaca cgatttttga attcattaca gaggtggatc agtctgagct
     7981 gacgatttgt gctggtggtc gctatgatgg tcttgtggag tattttggtg gaccagcaac
     8041 ccctggcttt ggttttggac ttggtttgga acgtcttttg cttatccttg ataagcaagg
     8101 cgttgaactg ccagtcgaag aaggcttgga cgtttacata gctgttttag gggcttacgc
     8161 caatgtggcg gcgctagcct tgacacaggc cattcgccgt caggggttca ccgtagaacg
     8221 cgattacctc ggacgtaaaa tcaaagcaca attcaagtca gctgatgctt tcaaggcaaa
     8281 ggtagtcatc accctaggtg aaagtgaaat caaaacaggt caagctgtcc ttaagcataa
     8341 tcaaactcgt caagagatga cagttagctt tgatcaaatc caaacaaatt ttgccagcat
     8401 ttttgcagaa tgtatccagt aaagcaaaaa aactgaaaaa agtggtatga gtcattaaga
     8461 tactaaaaaa tcacacaacg tcgttgcttt aatagcaatg atattgtgtg attttgtgat
     8521 gttataccta tactaaggac tatttttcct atttttagta gtcagtttga aagcactctt
     8581 gtttggaatg gcagcagcta tgcttatagc tggtgatggg ttaatgctat tgttgagaaa
     8641 ctaaaacaat gttagagaag ataatgctga ctttatagat gttattgtct atggtttgct
     8701 ggtatagtcc ataatactgt tgaacaattt tttgaacatt tttaattccc aatccgtctt
     8761 ttttccgttg acttctggag gcaagctctt ttggatcaaa aaagttttcg atatcaatgt
     8821 ggagttgatt tttaaagagt ctcaccttta attgtatttg tttttcagct ttattttgat
     8881 tgcgaatagt tgcggcaatg ctattatcaa gtagatttcc tataatgact gaaataactt
     8941 cagtctttag gcttatgttt gtagggataa ggcagtgaat atctaacaca atgccattct
     9001 ttttggctac gactgctttt tgattaagta aataatttaa aatagtatca ttggtaaaga
     9061 aagtatctgt cccatctagc aggttaaggt tatgattcag taattgttgg gctttagtgt
     9121 actgcttttg ctccagaagt cctaatagga caatgttttg attatgtaga tcatgcttaa
     9181 gagccctaat gcttaattga ttttccttta cattttctaa atgcttcagt tctgactgga
     9241 atcgtaccct atctaagtta atgtcttgca tttgtaaatg ctgatctgaa atgtaagtat
     9301 acagatacag cgaagtgatt gtgataatga taaatccaag tgttagcagt attgtaaaca
     9361 agtcaaataa aggttcttct tttaatcgaa ggagctgtag cagtagcaga gaaagactta
     9421 tcattggaat aatagatagc tttagtatcc agttggtttg tgtttgctca tcaagccaat
     9481 tgtctgtagt ctttaaaaag agctgcttta acacaaatat aatgataata ctggatatgg
     9541 taagcaggtt tataaataaa aatgtcccac tgatagaaga gatttgatat ttaagagata
     9601 ttaaaatgat ccctaagctt gcttctagca ggatacctat gctttgaagt gtaacagacc
     9661 aaaagataca ctgtttcatg gagtaacgat agctactaga tattatcagt gatgttacca
     9721 aagaacaagt cagggttatc agtgaggcat agcttcctga tacaaaaaaa tgagtgcagc
     9781 attctatgaa tactaaaaaa gagagataac ctatgttttt aaaggtagct agctgaccat
     9841 ttttctgacg aaaaaaataa ttaacaatca caatattaac aactgatgta taaagatgaa
     9901 aaatagcgtt aatagccatt tactctcctt agcttggaaa agatgttctc ctgaataccc
     9961 ttcttaaatt tccgactgat aggaatgata aaaaagcgcg tgttatcaat agctaatgtt
    10021 atgtcattgt tttcaaattt atagaagtaa ttgacgttaa acacataaga atgatgggtt
    10081 tggataaatt gttcaggaag ctcttttagt aatgctttgg ttgataaaaa ggtagagtag
    10141 gtcttgtcct tggtatgaat gagtactttt cgtccttcct tttcaaaata gataatatcg
    10201 tttaagctta agctatagta ggagtggcaa gatgaaaagg taaaaaattt tttgtcaagc
    10261 tctaaaaccc ttagagctct atttaggcac tcaaaaaaat agggttcatt taaaggctta
    10321 atcaggtaat caaaggtttg cacgtgaaaa atgttttcca tgtattcttt gtggcttgtt
    10381 aaaaagataa taatagcaga gagattatct ttcctaatat gctcggctaa tgctattcca
    10441 gacatgttat ccatttcaat gtcaagaaga aaaatatggt aatcattaga cagtgactgt
    10501 attaattgac aaggatcctc gtaaatgtct aactccactg gaactaattg attatattgg
    10561 tataatagat cttctacagc tgttgcaaaa gctttattgt catcacaaag agcaatttta
    10621 agcatggtac ccccataatc ctatagactg tggtatttag tataccaaaa atgacatgaa
    10681 aagcgctatt ttttacaaaa taataataat agactgaatg ttttgataaa atgaatctat
    10741 gaaatgaggg agcaataatg actgaagtaa cagtgcgtaa accgatggaa acaatggaag
    10801 tttcatgggt agtcatttaa atactctaaa gtgggctgtt tttatcagcc tactttaata
    10861 tttttaggag ggtaaaaaat gaattatagc agaccttgta ttaaagatat ttatccaatt
    10921 tataaactga gtgataccat gtttcgaata ggcgctcaaa ttaatattac gacggaattt
    10981 aacgattcaa attatgaaac aggtgcttca tttacacata agctttggcc acatttcaaa
    11041 gagtgtccgg cttgtggtca tggcaacagt aatgattggg aaatatttag tcattatggg
    11101 taggagttaa tcaatggaac aatatgaatt aatggtgagg tcactttcaa aaaggtatgc
    11161 cagagatggc tcttatgcca atagggattt acattgtgtc tttaaatcca gtgaaataac
    11221 agccttgata ggtcataatg gagctggtaa aacaactcta ctaaaccaga ttattggtaa
    11281 tataaaacct gatgtgggtg atatttcatt tctagactgt tcgtttgtca agtcccctaa
    11341 aattgctaga aaaaatacgt caatgatgcc tcagctacat gcccccttaa aaggaatcac
    11401 aattaaacag gctatttcat caattggaaa aatcagaggg ctgtccggaa aattattgga
    11461 gacagaggtt caggaattaa ttcaagaact cggtcttatt aagtggcaaa atactgtcgg
    11521 agagaaactc tctggtggac taaaaagatt gacgtcgttt gcaatggctg ttattgctgc
    11581 tccgaagatt gttttactag atgagccgac aaatgatgtt gatcctataa gacgtataaa
    11641 attatggtta tacttaaaaa agatggcggc aaagggacat atcgttattg ttgtcaccca
    11701 taatatttta gaggttgaaa aatatgcaga tgcttattat ttgcttgaaa agggggaagt
    11761 aaaaagttca ggagcggtaa aaaccctatc cagcaatcca aagagtagaa tatccatttt
    11821 atttagagat caaaaagcct tggaagaata cccatttgct tactcacttg gtggggatga
    11881 caatgaagct ataacaataa tggataataa ggaaatgaca gcattattga attggttagg
    11941 catacatttg tcatcagata ccattgttca atatagtatc acgacgttag ggttaaatga
    12001 ttattatgag gagctgtcag atgaagaaga ttagtgttac ttaccaattt ctaagcttgt
    12061 taaattggag ctttattcgc cataaatcgt tgatattatt gtgtagcgtt attcaatttt
    12121 ttatgacaat tgcactggtt tacggttatt cacttattat tgctgatgat actgtgcaaa
    12181 cagtctacta tcttgcttct ggctcagtaa cgattggtat gattaccatt ggctgtacgg
    12241 tatcagcaca atcaatcagt agtgataaaa gagatggcat tgtgagctat attcaaacgt
    12301 tacccgtcct aagaagtttg atcctgctat ctgatctatt gatttggaca ttaactgctt
    12361 tgattggtgt tggtgtgtca attgcggttg tttatttaaa atttcaaata ttgccccagc
    12421 tgtccttagc gacgtttctt attttgccat tagttttaat gacaatgatc agtatgggtt
    12481 ttgccattgc ttattggtca actccaagta cgatgatgct ggtaacccaa ttattgttga
    12541 tgattggctt attgttttca cctataatgt atcctgcaga acgtatacct gaggtgattt
    12601 taaggggata tcattttctg ccatttatac cagcaggaga cttgattcga gagacggttt
    12661 atttggggca ttccatttca gttgtcaagc ttgtggtgtt actgttatgg ctggttgcca
    12721 ctgccttact ttcagtcaat tggctaaaca ggcaaagcta aggtataggc tctgctattt
    12781 cttaaaaact ctactcaaat gggtggggtt tttaattgtt ttttgttata ataagtggta
    12841 atgatatttt taattagaga aaggaacaaa gacaggtagg gagtgttgac tctttatttg
    12901 ctcttggtat cttatttatg aagcgtagca tgtatgcagg acacgtccga aaggaacata
    12961 ttggaagaac gattgtttta aaaggttggg taagtcgccg tcgtgatttg ggcggcctta
    13021 ttttcattga tttgcgtgat cgtgaaggag tgatgcagct ggttattaat ccagaggacg
    13081 tttcaggtga tgtgatggcg actgctgagc gcttacgcag tgaatacgtg attgaggtgg
    13141 aaggaagtgt tgaggcgcgt cagcaggcta atgataagct agctacaggt gcagtggagc
    13201 taaaggtttc aggcttgacc attcttaata cagctaaaac gacaccgttt gaaatcaagg
    13261 acggtgttga ggttagtgac gatacgcgtt tacgctaccg ttatttagat cttcgtcgtc
    13321 cagaaatgct ggaaagcttt aagcttcgtg ccaagacgac gcatgttatc cgtaattact
    13381 tggataatct tggatttatt gatgttgaga caccgatgtt gacaaagtca acgccagagg
    13441 gagcgcgtga ttaccttgta ccaagccgta tcagccaggg acatttctat gctttaccgc
    13501 aaagcccaca aatcacaaag caattgttaa tgaatgcggg ctttgatcga tattaccaga
    13561 ttgttaagtg cttccgcgac gaagatttac gaggagatcg tcagcctgag tttacacagg
    13621 ttgacttgga aacgtcattt ttatctgagc aagaaatcca agatattgtt gagggtatga
    13681 ttgcaaaggt tatgaaggat acaaagggca tagaggttaa gctgccattt ccgcgcatgg
    13741 cttatgatga cgccatgaat cattatggct cagataagcc agatacacgc tttgatatgc
    13801 ttttacaaga cttgacagat cttgtcaagg agattgactt taaggtattt tctgaggcac
    13861 aggctgttaa ggcaattgtt gtcaaaggac atgcggatcg ctactcgcga aaggacattg
    13921 ataagctgac agaatttgct aagcaatttg gtgctaaggg tctggcatgg ctgaaggtgg
    13981 ttgatggtgc atttactgga ccaattgcta agttcttgac aggtgtgaaa agtaagttga
    14041 cagagtcttt acagcttgag cataatgatt tggtcttgtt tgttgcagac accttagagg
    14101 tagccaacaa taccctaggt gctcttcgta cacgtattgc aaaagagctt gacatgattg
    14161 acatgtctca gtttaatttc ctatgggtgg ttgactggcc catgtttgaa tggtctgaag
    14221 aagaggagcg ttacatgtct gctcatcacc catttacatt accaacagca gagtcagccc
    14281 atgagctaga gggtgattta gccaaggttc gcgctgttgc ttacgatatt gtcttaaatg
    14341 gctatgagct tggtggcgga agccttcgta tcaaccaaaa agacatgcaa gagcgtatgt
    14401 ttagagcact aggcttcaca gctgaggagg ccaatgagca atttggcttc ttactagagg
    14461 ctatggagta tggcttccca ccacatggtg gtcttgctat tggtcttgat cggcttgtca
    14521 tgctgcttgc tggcaaggac aacattcgag aggttattgc ctttcctaaa aacaataaag
    14581 catctgatcc aatgacacag gcgcctagtc tggtatctga aaagcaatta gaggagcttc
    14641 agcttcaaat agaacatcat gattaaaaaa acaacctata ggaaaagagt aaaatacctg
    14701 attaatagag gagccaaaaa aattggcttg cttcatgccg taaaaagcat ttccaaggag
    14761 aagtatacag agaaaatttc ggcctcttta ctctatggca tattgtctag tatagctgtt
    14821 aatttctttt tccaaccggg ccatgtctac tcaagtggtg caacaggact tgctcaggtt
    14881 atctctgcca tcagccacca tttatggggc tttgagattc ctgttgcttt agctttttac
    14941 gtgactaaca ttcctctttt agtcttagct tggtataaga ttggtcataa atttacgatt
    15001 tttaccttta ttaccgttag tatgagctct ttctttatcc aaatcatgcc tcaggtgacc
    15061 ttgacgactg acccactgat taatgctata tttggtggct tggttatggg tttggggatc
    15121 ggtacaggct tcaagtctcg catttctagt ggtggtacgg acattatcag tctgacactt
    15181 agaaagaaaa caggaaaaga tgtcggtaac ctttcattga tgatcaatgg tgtgattatg
    15241 gcttttgcag gactgttgtt tggctggcag tatgcgcttt attcgatggt gactattttc
    15301 gtttctagtc gagtgactga tgcgattttt accaagcaaa agaaaatgca ggcgaccatt
    15361 gtgaccagct gtcctgacaa ggtgatccac atgattcata aaaagctgca ccgaggggta
    15421 accagtatca atgatgctga aggcacctac aagcatgagc ataaggctgt tttaattacg
    15481 attctcacac gtgaggaata tagtgaattt aagtggctga tgcttaaaac agatccaaat
    15541 gcttttgttt ctgttgctga aaatgttaga atcattggtc gctttgtcga atcagatgaa
    15601 gactaagaaa taggtatcaa tatgccagct aataagagct taaagcttaa aaattgttgt
    15661 tttattattc ttggctcagc tatttatgcc tttgcctttg tctactttta catggcaaat
    15721 cgtattgctg ctaatgggct agcgggactg acgcaggttg ctaatgcctt gtttcagatc
    15781 aatccttcaa taacgggtta tctgattaat ttgcctctcg tcctgttggg tgcaaggctc
    15841 tttggcagac gggcaatggt gtatactgtg accggtattt tatcacttta ttggtttgtt
    15901 tggctgtttc aacagctccc cctttttatt gacttagatc atgacaattt agtagtgtcc
    15961 ttgctggcag gaattcttgg tggtttaggt ggcggcattg tttttagaaa tggtgggacg
    16021 attggtggct cagatattat tgctaagctg atagaggata ggtttggctt gcagctcaat
    16081 caagccttat tagggattga tatttttgtc attgtggttt ctttgaccta tatttcaata
    16141 ccgcagatga tgtatgcttt gattgctagc tttatgtata gtaggattgt tcatctggtg
    16201 caaaatggtg gctattctgc acgcggaacc tttattattt cagattattc tcagactatt
    16261 tcacaattca ttatggagga gctcggtaga ggagtcacct atttacatgg tgagggtgct
    16321 tactctggtc gtgagaaaca ggttatttat gtagctctag gtcgatcaga tgtacgagag
    16381 ctaaaggcct ttatagcaca ggttgatccc aatgcttttg tttctttctt tgatgttaac
    16441 gaagtcaata gtccagaatt tattgccaca aaaagtaaat accataaaac gaaaaaaaga
    16501 taaaggctgg aatatcacat tcatagcctt tgattatgct aatgaaagcg cttggctatt
    16561 aagcttattg tagtgtagct attaaatggc cgtccttgag ctttcatctg gtacctaaca
    16621 aatgtaatga atagtgagga aagtgaatga caaatcttga caaatggcat cgtgtaagag
    16681 agctattatt aattgcggtg ggtgttgcta tctatacctt tggttttgtt aatttcaaca
    16741 tggctaatga attggctgag ggtggcgtag ctggaattac cttgattttg catgctcatt
    16801 ttgggatcaa tccggcttat tcgtcacttt tatttaatct gcctttattt atgttagggg
    16861 ctaagatttt tggaaggcgc tccctagcct taacgattta tggaaccgtt cttatgtcag
    16921 tctttatctg gctgtggcaa aaggtgccta tggagcttgg tttagagaat gatatgatgc
    16981 ttgttgcggt tgttgcaggc ttgtttgcag gaattggtag tggccttgtt tttcgatatg
    17041 gagcgacaac tggtgggact gatattattg cccgcattgc agaggaaaag tttggtgcta
    17101 agctggggca aaccctgtta tttgtagatg ccttggtatt aacagcctct ctcacttatg
    17161 ttgatttgaa gcatatgctc tatacattag tggctagctt tgtctttagc cagatgatta
    17221 gtgttgttca aaatggtggc tataccattc gtggtatgat tattatcact aagcagtcgc
    17281 aagccgcggc gcaggcgatc ttgacagaaa tcaatcgagg agtgacttat ttaaagggac
    17341 aaggcgctta ttctggtcat gattataata ttatgtacgt gacgctcaat ccaacagagg
    17401 tgcgagaggt gaagcgtatt ttagcagagc tagatccaga cgcctttatc tctattattg
    17461 atgttgatga ggtaatcagc tcagacttca agattcgtcg caaaaatttt gacaaaccaa
    17521 ttgagaaggc tttacagaaa aaatccaaca tgttaaaata aagaaaataa gcagaaataa
    17581 gaggttgaga aaagccatga ttaacaatta actcattgtc aagcactaat ctatgattaa
    17641 cagcaaggga ttagtgtctg ctttgaggct tgggaatcag ggctttttgt gtgcactttt
    17701 tcaggccttt ctgatgatag aaaggaataa atatggaagc acttagtatt cagcattacg
    17761 ctttagatac agcagaaaaa aacttattga caatagattc tcttacattg aatcaaggtg
    17821 agagggtttt catcattggt gataatgggg ctggaaagac cagcttttta aagacaatta
    17881 tcggagaaag cactaactat agtggctttt tgcaggtgca tggagatatt gcttatgttc
    17941 cgcaaatcaa gtccactagc cctcagtcag gaggtgagag ggcgatgtct tacctaaaag
    18001 aggcttttca agcaaggcct tctctgttaa ttttagatga gccaagctct tatttagacc
    18061 atgctaatcg tgattggttg attaatcaat tgaaacgcta ccgaggaacc ttgctggtgg
    18121 ttagccatga tcggtatttg atcaatcaat tgagtcagaa aatatggttg cttgagcatc
    18181 aaacgatcaa gacttaccat ggcaattatg atgattatca gcgttctaga cagctagagg
    18241 aggataagca gctaagagct tttctggaat accaacgaaa gactaatcaa ctgaaaaaaa
    18301 gcctgaccag aaaaaaagtg caggccaaca aaatggctgt aaagaaaaag tcggtttctc
    18361 ggtcagattg gaaaaccaat tcctttgcgg gcagctatga ttcacaggcc aaggctatgg
    18421 caaaagcagc taaagctatg gaaaatcgac tcactcgaat gaaagaggtt aacagtccgc
    18481 gcaaaaaggc ttgggcaaaa ttaaaaaagg atccaaacga aggtgcacta ccaaatactc
    18541 ttttacacct acaagaaggt acccttacaa gggaccatca gttattgttt gactatcctg
    18601 gtattgtgat cagatcacat agcaggatag cgattatcgg gagaaacaag gctggtaaaa
    18661 gcagcttttt agatcagctg gcagcccagg ccttgtctgg attttatgcg caaaatctaa
    18721 ggataaccta ttttaaacag gaccaggctg acttggagcc ggatcagaca gcagtagagc
    18781 tcattagtcg gcagtccagc caagataggg tcaccatttt aaattatcta gctatgatgg
    18841 gcattgatta tgataaggcc aatcaaaagg tagctgtctt atctggtggg gaaagggttc
    18901 gtttggcgtt agtggctgcc ttgctgacag atcatcagct tttgatttta gatgagccga
    18961 caatttattt ggatcttgtc gctattgagg ctttggagtc ttgcttgatt gactatccag
    19021 ctgctctttt gttggtttct catgacctag catttgttaa caaggtagca acagaaattt
    19081 atgaggttaa ggatcatcat ttaacagcct atcattttga agactagcaa aaaagcctag
    19141 gctagcttat cctcgctagc ttaggcttat tagtctacat ttcatttggt gcctcaacac
    19201 ccaatagacg aagcgcttct ttgaggacga ttgcagttgc atagcaaagc gctaagcggt
    19261 tgtcacgttc tggatcgtct tcgaggatac gggtatgcgc ataatatttg ttaaagcttt
    19321 gtgccaagtg aatagcaaat tttgccatga ttgatggctc aaagttatca aaagcacgct
    19381 tgatgatacg tgggaagtcc tggataagct taatgatttc ccagctttca ggatcattaa
    19441 ggctatagct tgtatcggta gctggcgtaa agcttgcttt acgcaggata gattggatac
    19501 gtgcgtgtgc atattggacg taaggaccgg tttctccttc aaaggatacc attgcttcaa
    19561 gatcgaagtc atagccattc atacggtctg tttttaaatc atagaacttg atagctccca
    19621 caccaacagc atgagctact gcttccttgt tggcaagctt aggattttta gcttcgattt
    19681 ggtttgctgc tctgctgatg gcttctgcaa ccgttggctc aagcaaaatg acattaccct
    19741 tacgtgttga taattttgca ccgccctttg tcacaaggcc aaaagcaacg tgtgtcatgt
    19801 catctgacca atcgtagccc atttctttaa gaacagcctt taattgcttg aagtgtgcag
    19861 cttgctcgtt gccaaccacg taaactgatt ttgcaaaatc ataggtacgc ttgcggtaaa
    19921 gggcagcagc tagatcacga gtaatataaa gcgtagctcc atctgatttt ttaatgagag
    19981 ctgggtgctc aataccatat ttttcaaggt taaccacctt agctccctta gattcgacta
    20041 gtaggccttt gtcctcaaga agctcaagga cctcatccat tttatcattg tagaaggctt
    20101 caccattata gctatcaaag ctaactccta gctggtcata gagtcggtta aactcaatca
    20161 agctttcatc gcggaaccac tgccaaagct ctgtagcctc ttgatctctc tcctctagcc
    20221 tgcggaacca ttcacgtgcc tcctcatcaa gactaggatc agtttctgcc tctgcattga
    20281 ttctcacata gagctttaag agctcatcaa ttgggtgtgc ttgaacagcg gcctcatttc
    20341 cccacttctt atacgctaca atgagcatac cgaattgctt gccccagtca cctaggtgat
    20401 tgattttaac aggcttatag cccatttttg caaagatatg agcaagactg tccccgataa
    20461 ctgttgagcg caggtgaccg attgaaaatg gcttagcaat gttagggctg gacatatcaa
    20521 tagcaatatg acgtccttgt ccttcatcct gttgagcata gtcagctccg tcagcaatca
    20581 cctgtgtaag aacctgtgca gaaatgctag ccttatctaa aaagaaattg acataaggac
    20641 caacagcagc aaccttctca aattggctgg cgtcaatcct ttcagctaaa tcactagcaa
    20701 tagcttgtgg tgctttgcga agcgcctttg ctagactaaa ggctggaaag gctaagtctc
    20761 ccatgtcaga atttttgggt gtttcaagta agttaaaaat ggcagcctgc tctagttcag
    20821 gaacaatctt agcaatctca gctgcaatca gagttttagt gtccatattg cttctcctaa
    20881 aaatagtttg tcaccctatt ctaacacatt tcttggaaat aaacgaggtg tctattgaga
    20941 aattatacta gaaggcttgt aggtgttttg gggaacaaag ctaaagaatt agagcagcaa
    21001 agcttgccaa atctaagggt ctaatgatat gagcaagaaa taatgcttcc ttaaaataaa
    21061 gcaaattgac agagctgaga tgaaatacta ccattttttt gttataattt gagaggataa
    21121 ttatacattg gggagatata tcatgaataa aatagaacgg cagcagcaaa tcaagcaact
    21181 tattcaggct gagcacatcg gtacacagga ggagattaga cggcttcttc aaaaggatgg
    21241 tatcgtggtc actcaggcta ccctatcacg agatttaaga gaaatcggat tacttaaatt
    21301 aagagatgac agaggtaagc tatactatag tctttctgag cctgttgcca caccatttag
    21361 tccagatgtg cgcttttatg tcctaaaggt tgaccgggcg ggctttatgc tggttctcca
    21421 taccaatctg ggagaagcag acgtgttggc aaatcttatt gacaatgatg ccattgagga
    21481 cgttttgggc acgattgcgg gtgctgatac cttacttgtt atttgtcgtg atgaggagat
    21541 tgccaagcgc tttgaaaaag atttagctgc tggtctataa tatgccttac cgcgaatcct
    21601 tacatcagct gatagcagca ctggaaaagc actcaagcat tatagcttat aaggaggctc
    21661 agcagcactt gcttcaaagg actgattata atcaaaaggc ctatcagatg aagcgacatc
    21721 aacaggacac ctatcttttt cgtcaaatcg ctaaggataa agcagctgaa gaatcagctt
    21781 ttaaggctca gcaattacga gaagatttag atcatcaacc attgatagat gattatcgtg
    21841 acaaaatgca aaacgctagt gacttggttc ggtacattac agggactata gaagatgaat
    21901 taaataagga gttcaatgat ggcaaaggct aatgtttctc ccggaatgca gcagtatctg
    21961 gacatcaaaa aggattatcc agatgctttt ttgcttttta ggatgggaga tttttatgag
    22021 ttattttatg aagacgctgt taaggcagcg cagattttag aaatcggctt aaccagtcgt
    22081 aataaaaatg ctgacaaccc aattccaatg gcaggtgttc cctatcattc tgtccaacaa
    22141 tacatcgatg ttttaattga tttggggcat aaggttgcta ttgctgagca gatggaggat
    22201 cctaagcaag cggtcggtgt tgttaagcgt gaggtggttc aggtcattac cccagggaca
    22261 gctgtggact caagcagacc tgatagtccc aataattttt tggtggctgt tgattttgat
    22321 ggcaaggctt atggcctgtc ttatatggac gtctctacag gagaattttt tgctacagac
    22381 ctagcagatt ttgccagtgt caaaagtgag attcaaaacc tgaaggcaaa agaggttctt
    22441 ttaggctttg aattatctga agaagagcag gctattttag taaagcagct gaatcttttg
    22501 ctgtcctttg agatgacagc actagaggat tcgcctttga ttgatcatca gctaacagca
    22561 gtcgagctgt ctgcagcagg taagctgcta cactatgttc atcaaaccca gctgcgtgag
    22621 cttagccatc tacaggcctt ggtgcactat gatattaagg attatttgca gatgtcttat
    22681 gcaaccaaat caagccttga cctgcttgaa aatgctcgta ctggtaaaaa gcatgggagc
    22741 ctttattggt tgcttgatga aaccaaaaca gccatgggta tgcgtctatt aagggcttgg
    22801 attgataggc cacttgtgac tagtgaggcg atcctagaac gtcaggaaat tatccaggtg
    22861 tttcttaatg cttttatcga aaggacagat ctaagcgata gtttaaaggg tgtttacgac
    22921 attgagcgct tgtctagtcg tgtatctttt ggaaaagcaa accccaagga tctattacag
    22981 ctaggtcata ctttggccaa agttccttat atcaaggcta tcttagaggc ctttaacagt
    23041 ccttaccttg acaagcttgt caaccaaatt gacactttgc ctgagctaga gcacctgata
    23101 cggtcagcta tagatccaga tgctcctgct actatcaatg aaggcaatat tatcagaaca
    23161 ggctttgatg aacggctgga tcattaccga aaggtcatgc gagaaggcac cggctggatt
    23221 gctgatattg agacaaaaga aagacaggcc agtgggataa gcaatctcaa aatcgactat
    23281 aacaaaaaag atggctacta ttttcatgtg accaactcta atctaggtat ggttcctgac
    23341 cattttttta gaaaggcaac attgaaaaat tctgagcgct atgggacagc agagctagct
    23401 aagattgaag gacaaatgct tgaggctaga gaggagtcat ctagcctgga atatgatatt
    23461 ttcatgcgta ttcgtgctca agtggagacc tacatcgata ggctgcagca gctagcaaaa
    23521 gctctagcaa ctgttgatgt cctacaaagc ttagcagtgg tcgcagagaa gaatcactat
    23581 gttcgaccat tatttaatca agagagcaag attgcgattg acaatggtcg gcatgctgtt
    23641 gttgaaaagg ttctaggtgt tcaggagtat attccaaaca gcatttcctt tggtccacag
    23701 acaagcattc agctcattac aggaccaaac atgagtggga agtctacgta tatgagacag
    23761 cttgctttga cagtcattat ggctcagata ggctcatttg tagctgcaga atctgctagc
    23821 ctgcctttat ttgacgctat ttttactagg attggtgcag cagatgattt gatctcaggc
    23881 cagtctacat tcatggttga gatgatggag gctaatcatg ctatcaagcg agcaacccct
    23941 cattccctga ttttgtttga tgagttaggg cgtggtacag cgacctatga tggtatggca
    24001 ctagcccagt ctatcatcga atacattcat gatagagttg gtgcaaagac tatgtttgcg
    24061 acccattatc atgaattgac agagctgtca accaagttga caaagctggt taatgttcat
    24121 gttgcgacgt tagaaaaaga tggaaatgta accttcctgc ataagattgc cgaaggtcct
    24181 gctgataaat cctatgggat tcatgtggcg agaatagctg gattgccaga ggatttacta
    24241 gccagagctg atactgtgct aaccaagctg gaagctcaat cacaagcaag agagtccgtc
    24301 ttatcaacta cagaagtaag agagactcag cagctggcta atcagcagct atcacttttt
    24361 acagatgatg gctcctctag cgagattatt aaaaggcttg agagtgttga tgtgatgaat
    24421 ctaactccca ttcaggccat gaccgttctt tatgagctaa aaaagctact gtaaaagcta
    24481 gtatcagatg ttaaaggcac ttgtaggctc accaggccac aggtgctttt tggtttattg
    24541 accataagac ccttgctagc tctgatgctt ggctctttta gttttatgtt ataatagtcc
    24601 ataagaatgc gaggaaatat atgacaacaa ttatcgaatt acctgaggtt ctcgccaatc
    24661 aaattgcagc tggtgaagtc attgaaagac cagcaagtgt tgttaaagaa ttggttgaga
    24721 acgccataga tgcaaagagt agtcagatta ctgttgaaat agaagagtct ggcttgaaaa
    24781 tgattcaaat cactgacaat ggcgaaggga tgtctcacga ggacctgccc ctgagcctgc
    24841 gtcgtcatgc cacaagtaaa atcaaaagtc aaagtgattt gttcagaatc agaacacttg
    24901 gctttcgagg agaagctttg ccttcggttg cctctatcag taaactaacg atcaaaacag
    24961 caacagctga tgcagagcat gggtcaatat tagttgctag tggcggtaag attgagcagc
    25021 tggaagctgt ctcaacacct gttggtacaa aaatcaaggt agaaaaccta ttttacaata
    25081 caccagctag actgaaatac atgaagagct tacaagcgga gctggctcat gttgttgatg
    25141 tcgtcaatcg cttgagcctg gctcacccag agattgcttt tacattgatc agtgatggca
    25201 agcagctaac acaaacctct ggggctgggg atttacgtca agcgcttgct ggtatctatg
    25261 gcctgaatac tgctaaaaaa atgattgaca tttctagtgc tgatttagat tttgaagtgg
    25321 gaggctttgt gagtctgcca gagctgacaa gagctaatcg taattacatt actatcctga
    25381 tcaatggtcg ctatattaaa aatttcttgt taaatcgagc cattttagat ggttatggct
    25441 ctaagctgat ggtgggacgc tttcctatag ctgtcattga tattcaaatt gatccttatc
    25501 tggcagatgt taatgttcac ccaaccaagc aggaaattag aatttctaag gagcgtgaat
    25561 taatggctct gattagtaca gctatttcag agagcctacg agaacaagac ttgattcctg
    25621 atgccttgga aaatttagct aggtccagca cacgttcatt ttcaaagcct gagcagacca
    25681 gtttgccttt acagcctagt cagctttatt atgatccgca aaaaaatgat ttctttacca
    25741 aagaaacagt ggtttcagag gatagcccgc agggctttaa ccatgaaact ttggttgaca
    25801 gtggtgtcaa gcaggttgac aatttgcagc tggccaagac tgaatctgaa gcagctgctc
    25861 caagtgttaa atatgctagt cggccagatc ctatgctttc tgatggtgag cacccgggtc
    25921 ttgatgtcca caataagcaa aaattatctc agatgcttga tcgtttagaa aatgaagagc
    25981 agtcggtctt tccagagctt gattattttg gccaaatgca tgggacctac ctttttgccc
    26041 aaggcagaga tggcttgttt atcattgatc agcacgcagc tcaggagcgc gtcaagtatg
    26101 agtattatcg tgacaagatt ggtgaggttg acaatagcct acaacaattg ctggtgcctt
    26161 atctgtttga gttttccgga tcagatttta ttaatcttca ggaaaaaatg tcgcttttga
    26221 acgaggttgg tatttattta gagccttatg gcaatcatac ctttatcctt agggagcacc
    26281 ctatttggat gaaggaggca gagattgaat ctggtgttta tgaaatgtgt gacatgctgc
    26341 tgttgacaaa tgaagtatcc atcaaaactt atcgtgctga gctagcgatt atgatgagct
    26401 gtaaacgttc catcaaggca aaccatagct tagatgatta ttcagcaaga cagctgcttt
    26461 tacagcttgc tcaatgtaaa aacccctata actgcccaca tggtagacct gttttgatta
    26521 acttcagcaa ggcggacatg gaaaaaatgt tccgtcgtat ccaagaaaat cacaccagct
    26581 tgagagaatt gggcaaatac tagagaggat agcatgcgag aatttttcca gttacctaag
    26641 caaatacaaa ttcggcaatt tgtgcgcttt attaccatta cgcttggcag tagtatcttt
    26701 ccttttatgg cgatgtacta tacaagctac tttggcgcct tttggacagg catactaatg
    26761 atggtgacta gctttacagg ctttattggg accttatatg gaggtcattt gtcagatgct
    26821 attggtcgta agaaggtaat tatgcttggt tcagttgcga gcaccttagg ctggctgctg
    26881 accattttgg ccaatgttcc aaagacggtt cttccttggt tgacctttgt gggaattttg
    26941 ctggttgagc ttgcttccag cttttacgct cctgcctatg aggctatgct gattgattta
    27001 acagatgata gcaatcgtcg ctttgtttat accattaatt actggtttat taatatagcc
    27061 attatgcttg gtgcaggtat ttcaggactt ttttatgatc ggtatttctt agaactgttg
    27121 attgctttac tgattattaa tatcgtctgc tttggtattg cctatcgtta ttttggtgaa
    27181 acgaggcctg agcattaccg ctttgagcat ggtattggta ttctagcagg ttttgctaac
    27241 taccggcaag tctttaagga tcgcgctttt gtgttattta ctatagggac gattttattt
    27301 agcagtattt ggttgcagat ggacaattac gttccggttc accttaagct gtattttgaa
    27361 gagactgatg tgctcggtat tcatctgact agctcaaaaa tgctgtcact gatggtcttt
    27421 accaatacct tgctgattgt gctgttgatg acagttatta atcgcttgac agcaaggtgg
    27481 agattattac cacagctggt gatcggatcg gttatttttg cctttggtat gctgttgtca
    27541 tttacattta ctggcttttt tgctatttgg tgttcagttg tggtgtttac cattggtgaa
    27601 atgctaaatg tccctgccaa tcaagtgtta agagcagaaa tgatggatca gtctaaaatt
    27661 ggctcctaca caggctttgt ctcgatggcc cagcctttgg gagctattct agcaggtttg
    27721 ctggtttctc ttagtcattt tacaggacag gctggtgttc agctagcatt tgttttgatt
    27781 gcctgtgtgg ggctttatgt gattgtttta tctgcgaaaa tgaagaaaaa ggtgtagtat
    27841 gtacgattat attaaaggtc agctaacaaa aattactgca aagtatattg tggtagaagc
    27901 aaatggttta ggctatatga taactgttgc caatccttat agctttacag actgtgtcaa
    27961 ccagcaggta acgatctatc ttcatcaggt gatcagagaa gatgctcagc tgctgtttgg
    28021 ttttcacagt gaggaagaaa aggacgtttt tttgaagctg atttcggtat caggtatcgg
    28081 accgacgact gccctagcta ttgtagctgt agatgataat agaggactcg tcaatgccat
    28141 tgataatagt gatattacat atttgatgag gttccctaaa atcggaaaaa aaacagctca
    28201 gcaaatggtg cttgatttag caggtaagtt cgttgaagca cctaaggagg aaagcagcaa
    28261 gccccctaaa gccaagcaac aggggaatga acagcttgat gaggctgtcg aagccctatt
    28321 agcccttgga tataaggcga cagagctaaa gaaaattcga gccttctttg agggaacaag
    28381 tgagacagct gagcagtata tcaaatcagc tctgaaaatg ctaatgaaag gctaggagct
    28441 tcatatgaaa cgttgcgcat gggtaccaca agataataag ctttattgtg attaccatga
    28501 cttggagtgg ggaaggcctg tctatgatga tcgcgctctt tttgagctgc tttgtcttga
    28561 aagctatcag tcaggcttat cttggttaac tgttttgaaa aaacgtccag ccttcagaag
    28621 tgtttttcat cattatgata tctcagctgt ggcaagcttt agtgagcagg aaatggctgc
    28681 tgccctgcaa aatgcagcaa ttatccgaca caagccaaag ctaatagcca ctgtcaacaa
    28741 tgcagcggca gtccagcgca tccaacaaga gtatggtagc ttttccagct atctttggaa
    28801 ctttgtagga ggtcagccaa ttgacaggct tgtcaacgat gacaacccag cgcccgctca
    28861 aacagcccta tctctcaagc tatctaagga cttgaaaaaa cgtggcttta agtggctagg
    28921 accaacaact gtttattcct ttatgcaggc agcaggattg gtcaatgacc atgaagagaa
    28981 ctgtgagttt aggtagaatt aatcgcctct ttggagtgat gtttcatgag cctatcaaag
    29041 agagcttgat aaaaacagcc caatcttgat tgcttatagg atgatgtata agagctatgt
    29101 ttttgctccg tactttaagg atagatgatg aatcccctta tttaccctgt agcgaatgtt
    29161 gtaagcttct aatgggttta aggttttagc ctgttactgc tattgccagt aagctacagt
    29221 ttgatcaggt agttatattg gattgcctca acgattgtgt tgctgctggc tggtgcttct
    29281 ttctataact tattttggtg catgtgattg tggctctaaa agttataaca gagtatcggt
    29341 acgattggtg ttaccccttg gtttctattt ttttcttatc agccagtctg gcatttacag
    29401 cctataataa aagctaccgc ttaaaaattt cttagcggta gttttttagt tcatgttgca
    29461 aggtttctag aagttcagtt tcttctgtca actgtagtaa ttgtaagcct ttattaatta
    29521 ggtgatcatc attacgacaa ataccgagac gaacttggga aaaacctaag ctatcatagc
    29581 gtttaagctg tctagctaat ttgattgtta gtaaggtaat ttcttcgcac tcctttttga
    29641 ggttgtgata gaggtaaatg gttgaaagat tggttagtaa agcatattca gatgatttga
    29701 tattgcggta atctttatat tttgctaggc tatctaggat tttttgactg atgttttcaa
    29761 ttatttcgat aggaaagtga aaaagaatgg tatgtagtaa ttgtaaatct ttctcatacc
    29821 aagtatcttg ttttacgagg gaattccaga ttttataagc tagctcttgt aaatcttgat
    29881 tgtttttaac gccttttttc ctaagactta tcatgacttc gacactatct aaaatataag
    29941 aaatgggaat atcattttta tttttaaggt aattgaagca tttttgacgt aatttttcta
    30001 attcagtaat atttacagct gatacctgat tataaaattg gtttaaaatg tcctgccttg
    30061 tgctaggatg ataagtgttg cagacatatc taaactcttc cagtgtcata ttgagttggt
    30121 ttaataaaaa aatcattgta tcaaatttag gaatgacttg tccgctttca atacgagcta
    30181 gtgtagaacg agctaaaaag tctccacaga tcttttcttg tgttaatcct ttagattttc
    30241 gtatagcttg ataaatttta ccgtaatccc aacgcataaa acacctctaa aatgttacta
    30301 aatgctacaa aaaaataaaa tctacaatag tattttataa tagcatttag aaagagtaaa
    30361 ggaggaaaat ttatgaggag acatctaaag gttgtattat tacttgcagc actattggca
    30421 tttattgtaa atgagggtaa ttttccatgg tggccttggg gaccatagta cttaactgat
    30481 tactgttatg ttgttgccat tagactatct agattaatca aagagtaaaa tacaagtagc
    30541 ttagtgaaag acattttaag aggagaaaag catatgaaga aacgtttagc atttatatta
    30601 gttgcttttg gtattttggg atttagttta ggaaatgaag ttttagctgc agatactgca
    30661 cctgcaagtg caactatggc aacagatagt gatgtgagtt tttacaatgg agaactgttg
    30721 aaaaaatatt tggtccaaag tggtgataga ttgtattttg attatgacaa agctattcaa
    30781 gataaagttt ctgatggtgt aatagatatg ggattccttg ttgagacaat tagtgaggac
    30841 tattcacaac aaacgtttac ctctcgaaag tatttcaagg caggatggca gctttatggt
    30901 aattattgtg gacctggcca taacggaaat cattttactt tacctgttat tgatgtttta
    30961 gatcaaggct gtcaaaatca tgacagttgt tatcgatggg gagctgggat tggtgcaaat
    31021 tgtgaatgca atcgtcagtt agtaaattac attaaagtat atcgacggtg gatgccagct
    31081 catgccttgg gggttgctga tgctattaga gtatattttg aaacggtagg tgctattgga
    31141 tgttaacctt aaaaaatatt atcaatcgat actacatgta ttatgtattc cttattgttg
    31201 tgatctggat tgggatgttt tttgtacgat gggatactac tgtggctggt gtattactct
    31261 atccactgat tatgaagcag gtatttatcg tactaggagt agttgcgatg ataatggcca
    31321 ttatttctag aaaaattgtt cttggaattt ttggtttact atgctgtgct gctttttgga
    31381 ttaatctttt cttagctttc tatctattac ctggactttt gggaaattag cgattaaact
    31441 gtttttgatg ttttgaagat gagaaacaga ttgtttttct gtaaggcttc ctgttacttc
    31501 tcaaatgctt tggagtatct ctttatcatt tgttcactgt tgacaacgtt aaaaagatta
    31561 ttccaaacat gggaattgct gcttcagggt attccttgtt aatattggat tgattagttg
    31621 ttatttatgc aaaatcctta gagcattgct ttctcattct tggttcattt gaataaaatg
    31681 taactaaaaa aactttgtaa tcaattcaaa ttgtcacaag tataaaagta aaaaagcgac
    31741 tttgttagtg atctgatatt cggaagtcct atcattgctc gctttttgtt ttttgaggtt
    31801 gatttttatt ccgaaattgt tgtgaataag tgcaatttta agctaagaat tacctaaaat
    31861 cttttgaaga ttactgctta gcttctaata cctatttatc ggtgtgttga taattggaga
    31921 gatagcggga ttgtcatatg aaataaattt tagaaaattt aaacaagtta ttctgattat
    31981 tattatttca acataagtct ttatttgatt atcattgaaa accattaatt catctaaaat
    32041 tatttcaatg cttcatggat gattcttttt ttgttaaaat gagattgaat gtcgaataga
    32101 taagtaggtg ggaaaatgaa agctgaactc attgcggtgg gaaccgagat tctgactggt
    32161 cagattgtga ataccaatgc tcaattttta tcagaaaaaa tggcggagct tggtattgat
    32221 gtttattttc aaacagctgt aggagataat gaagagcgtt tgctttctgt tattgatatt
    32281 gctagccagc gaagtgattt agtgatttta tgtggtggtc ttggtccaac agatgatgat
    32341 ctaacgaagc agaccttagc taagtatctg ggaaaagctt tggtctttga tgagcaggca
    32401 ggtcaaaaat tagatgcttt ttttgcacat cgtaagcagg ctgctaggac accaaataac
    32461 caacgtcagg cgcagctgat tgaaggctct attgctttgc aaaatcaaac aggacttgca
    32521 gtaggtgggt taataactgt agatagggta acctatgttg tcttaccagg gcctccaagt
    32581 gagctaaagc ctatggtaaa aaatgagctg gtgccccttc tttcagctag tcatgccagt
    32641 ctatattcaa gagtgctgcg tttttttggc attggtgaaa gtcaactggt gactgctctg
    32701 gaggatttga ttaagcatca aacagatcct actattgctc cttatgcaaa gaccggcgag
    32761 gtaacactgc gactatccac aaaggctgac aaccaagcat tagctgatga aaggctgaat
    32821 cgactagagg cgcagctctt atccataaga actgtagata atcaaccctt acggcgtttg
    32881 ctttatggct atggggagga taattccttg gcgcgtgaga cctttgagct attgaagcga
    32941 agtggtaaga cgataacagc agctgaaagc ttaacagcag gactgtttca agctcagtta
    33001 actgattttg cgggagcttc acaggtgttt aacggtggct ttatcaccta cagcattgaa
    33061 gaaaaagcaa gaatgcttgg cattccattg ggtgagctac aaaggcatgg tgttgtgagc
    33121 tcttttacag ctgagcaaat ggctgcacag gcacgctgct tgaccaattc agatatcggt
    33181 attggtctaa caggtgttgc tggtccagag gcactcgagg gacagccagc aggaacagtt
    33241 ttcattggcc ttgccactaa gaataaggta gaatctctta aagttgttat aggaggccgt
    33301 agccgtttgg acgtgcggta tattgctgcc ctatatgctt ttaatatggt tcgtaaaact
    33361 ttattaaaat cagagaattt gctataatta ggatagtgta ttttaggaaa ttagtaacta
    33421 gacagatgtg aggttatgct gtttattgct tgctagtcag cctaaataga ggagaaaata
    33481 ttggcaaaaa aagttaaaaa aaatgaagaa atcaccaaaa aatttggtga tgaacgtcgt
    33541 aaagcacttg atgatgcgtt aaagaacatc gaaaaagatt ttggtaaggg tgcggttatg
    33601 cgccttggtg agcgtgcaga gcaaaaggtt caggtgatga gttcaggcag tcttgcttta
    33661 gacattgcgc ttggagcagg tggctatcct aaagggcgta ttattgaaat ctatggacca
    33721 gagtcttctg gtaaaacaac agttgccctg catgcagtag cgcaggctca aaaagaaggt
    33781 ggtattgcag ccttcattga tgcggagcat gccttggacc ctgcttatgc tgcggcgctg
    33841 ggtgttaata ttgatgagct gcttttgtca cagccggatt ctggtgagca aggacttgag
    33901 atagcaggta aactgattga ttctggtgct gttgatttgg ttgttgtcga ctctgttgca
    33961 gctctagtgc ctcgtgctga gattgatggt gatattggtg ataaccatgt tggcttgcag
    34021 gctcgtatga tgagtcaggc gatgcgtaag ctttcagcct caatcaataa aaccaagaca
    34081 attgcgatct ttattaacca gctgcgtgaa aaggtagggg ttatgtttgg taatccagag
    34141 acgacaccag gtggtcgtgc tttgaaattc tatgcctctg tccgtctgga tgttcgtgga
    34201 acaacacaaa taaaaggaac tggagatcaa aaagacagta gtattggtaa ggaaaccaag
    34261 attaaggttg ttaagaataa ggttgctccg ccatttaagg tggctgaggt tgaaatcatg
    34321 tatggagaag gcatctcacg tacaggtgag ctgattaaaa ttgcttcaga tttagacatt
    34381 attcaaaagg ctggtgcttg gttctcttat aacggtgaaa aaattggtca gggctctgaa
    34441 aatgccaaga gatatttggc tgatcaccca gagctgtttg atgagattga ccataaggtg
    34501 cgtgttaaat ttggcttgct tgaagatact gaggaaagtg cagctgcaga tacagttgca
    34561 gccaaagcag atgagttggt tttagagcta gacgatgcca ttgaaattga ggattagtgc
    34621 ttagtattag attttcagat aaaggtgcta aaaagggctt aacagcgatc gtcaagccct
    34681 ttttagcttg tgtttaatca agctctgtat tggtctgctc aggagctagg ctgtacgctt
    34741 ggataatttg ttagctgagt ttatgttttc tttagggatt aactgttaag ctataaaagc
    34801 cctagaaaaa agggacttcc tacagacaag atagtggcat agtaagcttg cttgcaacta
    34861 gctcaatata ggattttggc cttggttaaa gggatcataa aagaaaacta aaaaataggt
    34921 ccaaagaccg atattgatta gaaaaaaact atgctacaat agaggtatca cgagatagaa
    34981 agtgagaaca acatgataaa aatttacacg atttcaagtt gtacgagctg taaaaaggct
    35041 aaaacctggc tgaatgccca taagctccca tataaagaac agaatttagg aaaagaacct
    35101 ctttcaagag aagaaatttt agctatttta tcaaagactg aaaacggtgt ggagagtatt
    35161 gtctcttcta aaaatcgtta tgccaaagcc ttaaattgtg atattgacga gttaagcgta
    35221 aatgaggtta ttgatttgat tcaggataat ccccgtattt taaaaagtcc gattcttatc
    35281 gatgacaagc gtcttcaggt gggctacaag gaagacgata ttcgtgcctt tttacctcgt
    35341 tctattcgta atattgaaaa tgcagaggcg cgtttacgcg ctgccttata aaaagctctg
    35401 tcagagcttt ttttaatatc ctaacaaatc tgaattcttg tttattcaat aaaaataagc
    35461 tataatagag cgtagcactt aaagttagaa agaaggtgta agtatgggat ttacagatga
    35521 aacagtccgc tttaatttag acgatggtga taaaaagcag attagcgaaa cgctgacggc
    35581 agtttatcat tcactagatg aaaaaggcta caatccgatt aatcaaattg taggttatgt
    35641 actaagcggg gacccagctt atgttcctcg ttacaatgat gctcgcaacc aaattcgtaa
    35701 atatgagcgc gatgagatcg tagaagagct tgttcgctat tatttgcaag gaaatggaat
    35761 agatattaga tgagaataat gggacttgat gtcggttcta agaccgtcgg tgtggcaatt
    35821 agtgatccac ttggttttac tgcccaagga ctagagatta ttaggatcaa tgaagataaa
    35881 caggattttg gctttgatag attagctgag cttgttaagc aatatcaggt tgatcgattt
    35941 gtcattggct tgccaaagaa tatgaataac actagtggcc cacgtgttga agcaagtaag
    36001 gcttatggag ataagattga ggagctcttt cacattccgg tttcttatca agatgagcgc
    36061 ttgacaactg ttgaggcaga gcgtatgttg attgagcagg cagacatcag tcgtggtaaa
    36121 cgtaaaaaag taatcgataa gctggctgcg cagctgattt tacagaatta tttagattgt
    36181 aactattaag gagaacagat gacacataat catgatcacg aacacgaagt cattacactt
    36241 gtcgatgagc aaggaaatga agcattgttt gaaattttat taaccatcga tggacgtgaa
    36301 gaattcggta aaaactatgt tttactagtt cctgctggtt cgcaagagga tgaatcagga
    36361 gaggttgaga ttcaggccta ttcatttaca gaaaatgaag acggaacaga gggtgattta
    36421 cagccaattc cagaggattc agacgctgag tgggatatga ttgaggaagt ctttaatagc
    36481 ttcttagacg aagagtaaca acctgaggca ttagctttaa aataataaat agcctagaat
    36541 cttggtgcta gcagcatggg ttttaggcta tttttatggt ttatcagaca gtaggagtga
    36601 tagctatttc tatgacctct aaatagccta ctgttaagag tgtttttagg gtcttgtaga
    36661 tgttgcaata gcctgtaatt tcgttgaagt tacttgctgt tgtctttttt agtttaagcc
    36721 ttaacaaagc ttataggaaa tgactcaact tagcacagca taagccgctt attttgataa
    36781 gtaaagaaat agccaatagc tacttttagc ttaaagctga tcattaccag tacccttagc
    36841 ttttctgggt attatttcga ataatcttaa tgggggtgat tttatcaaaa gactcagtca
    36901 agaagaaaaa agctttctaa agcattatag gctaaagaca ctgcaccgct ttaaagagct
    36961 gctgacttat gccagcattt gtcataaatt gactaaataa tagattttgc tatacttgta
    37021 atatgacatg tcaaggagaa acacattgag tcaattacat caagaagtta tgctggaaaa
    37081 ggtcaattat ttggtgaaag accacccatc gtcacatacg actaagtatg acatgaaggt
    37141 ccctagttta tataaatttt atatcttttt ctttagcatc atagcgagct tgcttacggt
    37201 tgcggttcct ttttttgcag atactgcaaa tagcgttcag tcacaaaatt tatacatcgg
    37261 aatgatgttg actaaaggtc agattccata tagtgacttg tttacaacag gaggctttct
    37321 gttttttgtg ctcatagctt tgagctatca cttgggaaca acggtatggt tggtacttgt
    37381 tcaagcgctg tgcttttatt tgacaggtgt ttatttctat aaattaatcc attatgtgac
    37441 aggtattcag aaggtggctt taggttttac agctatctat tacctattgt ctattagtct
    37501 tggatttggt ggcttatatg cgatccagct tgccctgcct tttgtcttgg tatcgctttg
    37561 gtttttaacc aagtattttg ctggcttggt aaaggacgag gcctttattc tctttggctt
    37621 tgcagcggca atagccatgc taattgagcc taggacgctt cttttttggc tgcttgcctg
    37681 cattgcgatt attgcttata atgtgtctca aaagcatttc gctcgaggct tttatcagct
    37741 gttagcagct atttttggaa tgcttttggt gttttataca gcaggctatt ttatcctcaa
    37801 tttacagatt ttgagtcctt atttggagca ggcgcttgtt tatccgttta gttattttgt
    37861 gacaggtgat ttatcgctga ttctcggttt aacagtccaa ttaggacttg ttcttggctt
    37921 gggactgtta acggggctgc tgacgtttat gaagcagcct aagctagagt ctgatcttgc
    37981 tatgaaatgg ctactagtct ttgttgtgtt tagctatgct ggtattgcgg ctatatcgca
    38041 tgattttcat acttatcacc tactgccttt actgccttat gctttgatct tgctatcaag
    38101 ctctgttggc cgacaatatg aggcaggact taggatggtt agtcatcgtc gtcgtaaggg
    38161 gaaaaatggt gcgagacggg ttattgctat ttatctaaat aagcatttct acgtgccagc
    38221 aatcataatg ctaggagcgg tttttggcac agcttatcag tatgtgacca gctctgctat
    38281 taatcaagag cgttctcaga ttgctcacta tctaagacag aggctaacgg aggaccaacc
    38341 catctatgta tgggacgata cgtcaaaaat ttacctggaa acgcaggcca agtcagcttc
    38401 acagtttgcc tcaccctttg ttaatctgaa aaaagagagt catcaacaga tgttagagga
    38461 tgagctacta cagaataagg cagtctatat tgtggtcaac aagcaaaaag cattaccaaa
    38521 ggcagtcaag aaaatagtga cagctaatta taaaattgac agaaagattg atgttaaggg
    38581 ctttagccta tatcagaaaa aataaataaa atcaatatat tgtgttggta taaaaaaact
    38641 taacacaata tattgatttt tttgtgtggc gtgatataat agtcgagtaa ggagatagga
    38701 catgataaca ttagaaaaag acaaagttat tgttcagcca gctattaagg ttattaaaag
    38761 agatggacgc ttggttaatt ttgatgcaac aaagatctac agtgcgctgt taaaagcaag
    38821 catgaaggta acacgcatgt caccgctcgt tgaagcaaag ctagaagcta tttctgaacg
    38881 cgttattgca gaaattatcg agcgatttcc tacaaatatt aaaatttatg aaattcaaaa
    38941 tattgttgag catgagctat tagccgctaa tgaatatgct attgctaagg aatacatcaa
    39001 ttatagaacc cagcgtgact ttgcccgctc gcaggcgaca gatattaatt tttctattga
    39061 taagctcatt cacaaggatc agacagtagt caatgagaat gccaataagg atagtgatgt
    39121 tttcaatacc cagcgcgatt tgacagctgg gattgttggt aagtctatcg gtttgaagct
    39181 gctgccagcg catgttgcta atgcccacca aaaaggtgat attcactacc atgatttaga
    39241 ttatagtcct tatacgccaa tgacaaactg ttgtttgatt gattttaagg gaatgctggc
    39301 aaatggcttt aaaattggga acgctgaggt tgaaagtcct aagtctattc aaacagcaac
    39361 agctcaaatt tcacaaatca ttgctaatgt ggcctccagt cagtacggtg gctgtacagc
    39421 cgatcgtatt gatgagtttt tggcaccata tgctgagcta aatttcaaaa agcatatggc
    39481 tgacgctgaa aaatgggtta ttgaggagct gcgggaaagt tacgcctttg aaaaaacaaa
    39541 aaaagacatt tatgatgcca tgcagtctct agagtatgag atcaacacgt tatttacctc
    39601 aaacggtcag acccccttta cctcattggg atttggtcta gggacctctt ggtttgagcg
    39661 tgagattcaa aaggctattt taacgattag aattaatggc ttaggcagcg agcaccgtac
    39721 ggcaatcttc cctaagctca tctttacggt caagcgtggg ctcaatttag agccagactc
    39781 accaaactat gatattaaga ccttagcctt ggaatgtgcc acaaagcgca tgtatccaga
    39841 tatgttatct tatgataaga ttattgagct gacaggatcc tttaagtcac caatgggctg
    39901 tcgctctttc cttcaaggct ggaaggatga acaggggcaa gatgttacct cagggcgtat
    39961 gaaccttggg gttgtaacca tgaatttacc tcgtattgct atggaatcaa atggcgatat
    40021 ggataaattc tgggagctgt ttaacgaacg attacacatt tgtaaggacg ctcttgttta
    40081 tcgtgtagag cgcgttaagg aggcaacgcc agccaatgct cctattcttt accaatatgg
    40141 agcctttggc aagcggctag ctaagactgg caatgttgat gagctcttta acaatcgccg
    40201 cgcaactgta tcattgggtt acattggctt atatgaggta gcaaccgtat tttacggtgg
    40261 gcaatgggag cacaaccaag aggccaaaga ctttacaatc actattgtta aggaaatgaa
    40321 aaaggcttgc gagacttggt cagatgaata tggctatcat ttctctgttt actcaacacc
    40381 atcagaaagc ttgacagatc gtttttgccg cctagatact gacaaatttg gcgttgttgc
    40441 tgatattaca gataaagaat actatactaa ttcattccac tatgatgttc gtaaaaatcc
    40501 aacacctttt gagaagctag attttgaaaa ggcttatcca gcagccggtg cttcaggtgg
    40561 ctttatccat tactgtgagt accctgtttt gcagcaaaat cccaaggcct tggaagctgt
    40621 ttgggactat gcttatgatc gtgtgggcta cctaggcaca aatacgccaa ttgataagtg
    40681 ctatgaatgc cattttgagg gagatttcac cccaacagag cgaggcttta cttgtccaaa
    40741 ttgtggaaac aatgacccta agacagtaga tgtggttaaa agaacctgtg gttatttagg
    40801 aaaccctcag gctcgtccaa tggtcaatgg tcgtcataag gaaatctctg ctcgtgtcaa
    40861 gcacatgaac ggatcaacca tcaagtatcc ggggatataa gccttggaga ataatctcat
    40921 tacacctata tcattgtaaa ggattgcttc atgcaagcag tcctttagtt atcaagacag
    40981 gtctgtaaca aagaaaggga gaaacatggg aaaataccag ttagattata agggaatgca
    41041 gcaagtagag aggtttcatg agaaacattc tgttgcaaaa acagacaaaa agtctcgagt
    41101 acagcagctt agagcacaat ttttagaaaa agcaaagcaa tcaaagaaat aatggcacac
    41161 tcagtaaagg cggtgaagaa tgctagatat tggaattgtt gggttaggcg ctatttcaca
    41221 aaaggcctat ttaccctata tgcgtcaatt aagaggaatc aattggcatt tatctactag
    41281 aaatgcgtta gtccgccagg aggtgggtca gctttttggt tgcgcaaggc tttacagcac
    41341 tgtcaatgag ttacttgagg ctaagttaga tggtgtgttt atccatgcag ccactaaggc
    41401 tcatttagag ctggctagtt tgtttttaca aaaaggaatt ccagtttaca tggataagcc
    41461 tttgacggag gatttcttta gcacgcaggc tctttatcaa ttagcagata agcacaatac
    41521 ctttttgatg gcagacttta atagacgctt tgcacctggt gtcaagaagt tgtcaaccct
    41581 gtcaaccaaa cgtaaagttg ttgttgagaa aaatgatatt aatagaccag gtgacaaaca
    41641 gtttaagctt tttgacttct ttatacaccc tttagataca gctttatttt tagttgatag
    41701 gaggcttgtt gcaggctatt ttcattatca gctgactgat aatgatttgc taagtcaggt
    41761 tagtgtaacc ttaaggacag aacagactat tatttcagca gctatgaatc tacagtcagg
    41821 tagcaggcgt gaggtgatgg aggttcagac acctaaagag acctatcacc tagaaaatct
    41881 agagaccttg cgagcttatc gaggggttga tcaagagatc aagggattta gtgcttggga
    41941 tactacctta tctaaacgag gctttgaggc tattgtggat tcttttttac aggctgtcaa
    42001 ggatggtgtt aaccctgtca agccagagac aagtctgttg agtcactgga tttgtcacca
    42061 aatttgtcaa tctcatgaag ctgatggcat attagatgtt tctcttccct tataaaggag
    42121 tgataatatg aagctacgaa gacctaaaaa gcaagatgaa gcgtctgttt tagaaatgat
    42181 ggcagagttt gaagactatc agtctcctca tgatggtggt ttttggaacg ctgagcattt
    42241 tgattatgaa aaatggttgg aatctaatgc tctgatggag gctggcttag ctatccctga
    42301 gaattgggtg cctgccatac agctcgttgc ctttgctgat caacaggcta ttggatttgt
    42361 caatgtacgc ttgagattaa acgaacagct actggtaaaa ggtgggcata ttggttattc
    42421 tgttagacct agccagcgtg gaaagggcta tgcaaagctg atgctaaagg aagccttgca
    42481 gcttgctcgt caaaagggca ttcgtgaggt tttagtgact tgtcattgca gcaatagtgc
    42541 tagtcggtct gttattttag ctaatggtgg tcagctgaag gattgcaata agggtattga
    42601 acgctattgg ataaaagcat aagaggcaat aatgaaggaa aactgttgga attctcccaa
    42661 accaaaagaa tggacatcag aggcattaag ccaaggacgc gttattgatt ataaggcatt
    42721 taattttgta gatggggagg gagtgcgaaa ctcactttat gtttcaggct gcatgttcca
    42781 ttgtaagggc tgctataacg cagcaacctg gtcttttaag gcgggtattc cttatacgaa
    42841 agagcttgag gagcaaatta tgactgatct tgcaaagccc tatgttcaag gtttgacact
    42901 tttgggcggt gagccctttt tgaatacggg aatattgatt cctttgatta agcgtatcag
    42961 aaaagagctg ccagaaaagg atatttggtc ttggacaggc tatacctggg aggaaatgat
    43021 ggaagaaacc caggataagc tagagctgtt aagcatgatt gatattttag ttgatggccg
    43081 ctttgatatc accaaaaaga atctgatgct gcaatttcgt ggatccagta atcagcgtat
    43141 catcgatgtt aaaaagtcac tggctgctgg agaggtggtt atttgggata agctaaatga
    43201 tggtgatcag tcctttgagc aaatgagccg cgatgatttg atttagtaga gacttatcaa
    43261 catcactaga cttgaaagct aataatgaaa gcatgatttt aggctcctgt ggtcttgctt
    43321 aaccaatcta ataaggggtt ttccccacat tatcctcata cttatccaca ggttgtgaat
    43381 aacctgttgg tttgtggata aaaaagagaa ttaaggggtt ctttaattct ctaggcctga
    43441 aaaagggttc tttttgatgt tttttcttaa aagaaagaga ggcaagtgac ctctcttgaa
    43501 atagtatact taggctttaa gcctagcttt caatatctct gaatgtctga ttttcttagg
    43561 agtcaggcat tttttaatgg cgatgggaag tacggcttgt gggtcgcttt gtgtgctaag
    43621 aggctttctg agctgctata tgtcaatgat tggtgatgtg acagctgagg cttgttcaca
    43681 ttctgaaagc actgatgttt ttcctagctt tcttttttga tgtagtagta attagtttcg
    43741 gttgatagct cctcattata gcaaaagcca gcaaagctca gctgcttaag tgcttccttg
    43801 gtttggacat tgttttctag acaggctgtt agaaaggctc ctcgagcttt ttttgaaatg
    43861 gttgaatgcg tcttgagctg tcctgatctt tcctccataa atttgggact tatccacagt
    43921 ttttgatatt cctttgaaaa aacatctcta aactcgttgg ataacagaga aatgatttgc
    43981 ttgtgatctt tagcaaactg atcgtagata gggcgccaat aatgcttaag gctttgccca
    44041 ttgatggtta ctttagtgtg aaaatcatgc cggtgctctg cgattttctc atcagtaggg
    44101 ataatgccat aaaaagacga ggtaatgtag acctgctttg agaggtagtc ttgctggtct
    44161 ttagagagat tgtcgcgctt gagatgacgg tacatgagcc cattaaagag ctgataagca
    44221 ggataagcag aactctgccc ttgagctatg gcctttagtc tcttggcttc cttgcttgct
    44281 gcttctatac ggatgctgta ggcccttgct agctcctcta gggatagttc agccatagcc
    44341 tctaatatgg gcaggctttt ttggggaagc tgatgtggat agcaaggtgg aactggtttc
    44401 atttctttag ctgttggaat taaaaaagtt aacataagtt tattgtagta aaggcggcaa
    44461 ccttctgtca agagtgggat acatttggtg gttatgtcat atgaaactaa tttttatatt
    44521 ttttacattt tgattagttt ttaaaaatat agtgatttag tgttgcataa cctctctaag
    44581 tatgttaata tatacttaag tctgtttgat aaacagaagc tcaggtcaag tgagtgttcc
    44641 acttacaata acgcagttga tgatggggag actcagactc agagtcaagg aaaagaaata
    44701 tagtcttgta ggattaccta cagggctttt ttctattttg aattgagaga tcaatataag
    44761 gtgatgtgct gttttttatt accttaaaca tttggatatt ggctattgac aaaaagtgta
    44821 aaggaaacta tactatatgt gtaaagttaa cttgacatat tggaggaacc atggaaaatc
    44881 ggatacaaga actccgtaag tcacgaggga ttagtcaagc tgatttggca gatatgatgt
    44941 gtgtcactag gcaaaccatt atctccttag agaaaggacg ctataatgcg tcattagagc
    45001 tggcctataa attagcgaca tttttcaatc tgactataga agacgttttc ttgtttgaag
    45061 agaagggaga atgagatgat atttagtgat ttaagcgtcc tgctgactca aaaaagccag
    45121 ctagcctatg ccaaaaggct gaagtatatg ggctttttcg ctctctgttt aggcggtttg
    45181 tttttgttgc tggcctttga cgtgagactg acgagctttg ctcagggaat gctggtaggg
    45241 cttggtagtg gtagcttatt attaggtgtt cgtgcttttt cagattgcct ttaatcctca
    45301 aaggctgaga gcctcttata ttaaggctta tgatgagcgt catcaggtag ttatcaagct
    45361 agctgctgta tcaaccttaa tcttattagt ggtgttgatt attggctgtt tgtgcttgaa
    45421 tgttttttgg agtttggttt ttggctttag agtattttta gagatttgtc tgtatacgat
    45481 cttgcttggt tttttaggca tcaagctatt gttagagcat atgatttagg aggcttcaat
    45541 ggaaacaaaa cattcagcag taaaggtcat catcagtaaa ttaaaatggt ttggcttagc
    45601 tcttcttgtg tttatgcttg agcaggctcc aacatttttg ataacaaaag aacagccaat
    45661 gtggcagaca cttcttcttg tggtcatttt tcttttgatt agtggaggta cttattacct
    45721 agctgtgaag cttcacattg tgggagatca agctattcct aagaatgact atcgggcact
    45781 ttggattggt ttgggagtgg tagctgtctt tgttgtcaag atgattggtg gtattctgtt
    45841 gtttttggag catggtccgg gagccaatac ggtcaatcaa gctgccttag aacaggcagg
    45901 cttatctccg attcttatgg ttacgctagt tgctattgtg gcaccaattg tggaagaaat
    45961 tgcttttcga gggctgcttt atgggaagct ctttggtgca gagtcttatc tgggcttgat
    46021 ttttagcagt atcatgtttg gcttgattca tgtgccaaca gattttggca gttggtttat
    46081 ctatggcggt atggggctgg tgttaggctt tgttttccat aaaacaaaga aggtcgaata
    46141 cacgatattg attcattttt tgaataatgc actagctgtt cttatcatgc ttttgctgcc
    46201 ttatcttcag tagtactgct tgagtaatga agggggtaat gaatgaaaaa tgatcgttgg
    46261 attgacaaaa aatatcaacg ttgggagaaa gtgtataaga gacttggtca ttctttactg
    46321 acaatcggtg tgttggtagg gacttatggg atttttttga ttattcaagg gaatcatcaa
    46381 acgggctttc tcctttttat cctggggcct atactattga ttgcgtcatg tctttgctat
    46441 tatgtgttta cagagccaac gtctttacga gaatatctga ttaatagcta tgatgagcgt
    46501 aaccgagcta ttcgtcagaa agcacaggcc tactgctttt gtctatttgc ttttctcttt
    46561 ttgatgcttg cgatattctt tccaaatatg acgatcaagg agctttttgg gtataatctt
    46621 ccgttgattg ttttcaatct gtatgtcatg attagagcct gggttagtaa acacatgtag
    46681 gtcatgttaa cacaaaggag tctagagcaa gggctttgaa tgaaactatt tttctaaaaa
    46741 cgcaaaaaat cgcgtgcagt aacagattag gccatgttac tgcatgcgat tttgttgttt
    46801 caaacgtgag ctcagaatga catatccttt ttagaaagaa taggtattta gggctgtctt
    46861 gagctagtct taggtaatga gcttggagct cattggtgat ggttaggata ggtctttagc
    46921 ttttttgatc gttgtgtcaa tggcagagca gacagaatgt gtcaggcctg ttttttcaag
    46981 atccatcaag cctgcaatgg ttgtgccgcc gggactgcag atcttatcaa tcaaatcatg
    47041 gggactatct gtgctgacta gcaggttctt ggcgctagct aggacagttt gactaacgat
    47101 actaagggcc ttgtctttag gcagtccatt tttgactccg gcctttgcca tagcttcgat
    47161 gaaaaggtaa agataagcag gacttgaccc tgctagagca gtaaaggtat caaaatcctt
    47221 ttcagctatt tcaaaggttg ttccaaagct gttggttagc tctttagcag tagctaataa
    47281 atcagcagtt actaagtcat taccagtcaa agcagtggtg ctttggagaa tttgagcatt
    47341 catatttggc atgatacgta ggagtggcaa atgagagctt gttaattgag ctagtctgtc
    47401 taaggaaata ccagcagcca ttgacatgat aggctgtttg aactgtagag ggctaagaac
    47461 agtctcaaag agctgtggct tgatccctag aatgatgaag tcaacctgat cgatcagctc
    47521 ttggtgagat tgggcgtagc ttaggtgcaa ttggccagca atttctttag agcgagctaa
    47581 ggatgagcct gagatgatta gctcgtgtgg tgtgtgtgtt aggccttgaa tgatagcagt
    47641 tgccattttg ccaacaccga taaatccaat tttcataata atgttcctaa aaatgaataa
    47701 aggctcaata ggctagagtg ctcattgaac cttagattcg cattttagcc ttatccttcc
    47761 tagtatttct tgattaaatc aactgttgag cggtcaagct ttttgacaat ggcttgcaaa
    47821 aaggcctgtg cttctacgaa atcatctaag gcgtacaagc tctgatgtga gtgaatgtag
    47881 cgagcgcaga caccgattgt ggttgaaggg ataccgccat ttttaaggtg agcagcaccg
    47941 gcgtctgtac cgcctttacc acaataatat tggaaggcaa ccccagcctc ctcagcggtg
    48001 gttaatagga agtctcgcat gttcttaagc atgatgtgtc cgggatcgta aaagcgtaga
    48061 agggttccat caccaatatg gccaggattg ccataaatat caccagcagg tgagcaatca
    48121 acagcaaaga aaagctcagg atcaaatgta gtggctgaca catgggcacc acgaagcccg
    48181 acttcttctt ggacatttgc tccagcaata agggtgttgt gaagtgtctg gtcttttagg
    48241 gcttctagca gctcagtgac catgagaaca ccatagcggt tgtcccaggc ctttgagatg
    48301 atattctttt tattggcagt taaaatggtt tcagactgcg gtacaataat atctcctggt
    48361 gtgatgccaa agctttcggc ttcagttttg tctgtaaagc caccatcaaa aacaatatct
    48421 gaaaccgctg gcagactagc agcaccattt gccccgcgca gaaaatgggg aggaactgag
    48481 cctgaaataa caggaatggc ttggccagcg cgagtgtata aggtaaagcg ctgtgagcta
    48541 acaactagtg gattccagcc gccaatttca acaacccgca gtgttccatc agctttaatc
    48601 tcgctcacca taaagccaac ctcgtccatg tgagccgcaa caagaatgcg aggagcttga
    48661 tccgccttgc tttcttttat cccaaatatg ccgccaagtc catcaacctc cactcggtca
    48721 acaagcggcg tgatcttagc gcgtaagtaa tcccgaacag tgtgctcgta gccggcgatg
    48781 ccgtctaatt cagtaacttc tttaattttt gaaaataaat caatcatttg tatactccat
    48841 ttgtcatgta agattaaagg tatcacgtct gcctctattc tatcattttt tagtgaagaa
    48901 tgggaaacag cttgagcata ggaaaagagt ttgggagatt aggtgtgtct ttcttgcttg
    48961 ataagctgct tattatcagt ttgattcaga tgagataact gctggtattg atggaatgaa
    49021 acagctatgc acaacagcct tgacaaggat cgacaggcct gagctgtctt atgctatcaa
    49081 ttgcacttag gtagagcagt agcctgatat tgatgtgatt agttgctctt gtcaggtggt
    49141 ttattagtat ttcctaaagt gtcagctagt cttggctgag attgttagct tttgctctag
    49201 cctattattc cctttttgtg ataaaatgaa aggtatgaat ggaaaaaaga cacgtattgt
    49261 ttcaggatta attggactgg gtctgctagc cggcttggga ttgaggctta aggaagtcta
    49321 tcaagaaaga gagcgtcaga gagtattggt tgaattgcgc gcctttttct cagccttagg
    49381 agagattgag gtcttgtaca tcaactcctt tagctcaaag cgtgatgatg tcactggtgg
    49441 ccttgtcatg acagatggta agacctatac ttaccattac cacaaaggaa gtattgattt
    49501 taaagaggat ttgacatgat tattccaaca tctaaggaag aacttgctag gctaattgag
    49561 acagagccta ggctggtttt gttttttaca gcagattggt gtccggattg ccagtatatc
    49621 tatcctgtaa tgcctgagct agaggctgaa aacccggata tgacctttgt ccgccttgat
    49681 cgcgatgatt ttatcgattt agcgcaggat tggcaaattt ttggcattcc aagctttctt
    49741 gttatggaaa aggggcagga gaagggccgt ttggtcaata gattacgaaa aacaaaggct
    49801 gagattagtg actttctagc agcctatcac taagaggaga aaatgagatg atttttgcat
    49861 ataataaaga gcaggtcggt gatgttttga tggtgatact agaggataaa aaagacatca
    49921 agcgacaggt tgagcgtaag gggagagtag cgcgtgtttt tgcagaagag acagggcaaa
    49981 cccttgcttg gaatattttt gaggcgtcag ccttaatcgc tgttgaggga aatgggcagg
    50041 ttttcttgtc tgaggaggag ttagcgattt taaatgcgga gcttgctcaa gaagggttta
    50101 ctgaacgatt agaggctagc ccagcccctg tttttgttgt ggggcaaatc attgagatga
    50161 ttcctcaccc agatagtgat catttgaata tctgtcaggt acagattgct cctgataagg
    50221 ctgtgcaaat cgttgcagga gcacctaatg ctgctgttgg gttaaaaaca attgttgcct
    50281 tgccaggtgc tatgatgcca agtggcagcc ttatttttcc aggaaagctt cgtgggaagg
    50341 aaagctttgg tatgatgtgt tctccacgcg aattggcctt gccaaatgct ccacaaaagc
    50401 gtggtattat tgagcttggt gatgctgcag cggttggtga agcctttgat cctgctaagc
    50461 attggcagag ctagcaggac ttgatcagca ttaaaatggt gtttagtcct tcttttgctt
    50521 ggtgaaaagc ctttggacct tgagccatgc agtgcttttt gctggtctgt gactgtcttt
    50581 agcttcagga tcgaagcatt agagtagctg cttaacttat tgtcagcgct gttgattgca
    50641 gtagcgctat gcttgtgaca agtgaaggca aagcctatca atgcccttgg ctagggctaa
    50701 aaattgtctt tagagtcact tttgaggtga gtagctcgct aatttcggta ttgaacggtg
    50761 cttaggtacc gtttttttaa gctttgctga gtgtgacatg ctgaaaaaag gccatgtctt
    50821 tatatggctt ttggtcacag atggctaatt caatcgtccg caacacttcc agccaatcag
    50881 gcttagcttt aacctcattt ggttgaagtc cgtagcatgt ccgcagtcca cgatagcctt
    50941 ggagcttcaa atcggtcttt ctgagtaagt catcaatact gtaggtctga cctgctgcaa
    51001 aggataaact ttcaaaggct tgtccattta gcacattaag tgccttgtca tagtcgtgtt
    51061 caaaaataac agagtggaga acttttccga cttgattgtg cttgatgagt gatagctgcc
    51121 ctttaggctt caatagacgt tccatctgag ctaggtagat cgcatgctct tttggggcga
    51181 tatattctaa gacattgtgg catatgatca tatcaaaggc ttgatcaggc agtttttcta
    51241 gcgcttctaa tgaacctttt attttatgaa tgctttcttg cttttgggca aataataggt
    51301 caggatttgg ctcaattgca gttacttcat tctggacggc taatgcctct gctgtgatgc
    51361 aaaagcctgc tccgaaatct aaaatagtct tgcctgctat ggggcctaat tgggcaaaga
    51421 tcaaatcata catgagcttt ccccagggcc ttgtgagcat gtcttgatag gctttaagat
    51481 taatagtcat tatctagttt tcctttcttt agctgctgtg agctattggc aggatttcta
    51541 aacttcacag cttgtcctta ttttaccatg ttttacgaat aataagataa ggaggtatga
    51601 catgtacaat aaagtaatct tgataggccg tttagtggcc aagccagaat taaacaagac
    51661 attaacggat aagcaggtcg ttcgatttac cttagcagtt aatcgtcggt ttaagacgac
    51721 gactggtgag cgtgaggtgg attttatcaa tgctgttgct tggggaggtt tggctgaaac
    51781 cttggcttcc tatgctagca aggggagtct gctgtcactt gatggcgagc ttcgcacacg
    51841 aaaatatgac aaggcgggtc agactcattt tgtgacagag gttttgtgtc attcttttca
    51901 attgctggaa agtcgagcgc aacgagctat acgtgaaaac aacgctgcta atgatttgat
    51961 tgatttggct ttagaggagg aaaagcttcc cttttaaaga cagctgctag cttactgtcg
    52021 ctaagggagt cagacactag cattgtgtat gctagagatc tcaacataat ctaaaaaatg
    52081 gcaacgattc taaaaaaaat cttgacacgt cttagaaaaa ggtttacaat gtatgacaat
    52141 taaaatgaaa gaaaacagga ggtgctggta tggtagcagt tagcacagct cagacgatga
    52201 ctaagcgtta ttactttagc ttctttagat agtgtttgta gacatgagcg catggataca
    52261 aacacactga acgttatgtt tgtatctatg gggctaaggg ctatttgagt tgtttgtcca
    52321 catagatgat atctcttcta agtggacacc atacagcatg tattttgtta tctcatgata
    52381 cctgtatagg accatttaga ttatctagat ggtcttattt ttatgcaaga aagaggaaat
    52441 gacatgagat ttaaacagtt atccttaaca gcctttatag ggcttttggc aatgctgcta
    52501 acggcttgtc gacaagaaac caaccaaaca catcaagctg ctagagttgg gattattcaa
    52561 tatgctgagc actcagccct agatgctgcg cgtgagggtt ttattgaggc gcttgagcag
    52621 ggcggcttta gagaggggaa gaacctgacc attacaacca aaaatgcaca gggtgatcag
    52681 gctaacctgc aaacaatggt ggagcagctg gcgggtaaga acgatttgca gcttgcgatc
    52741 gcaacgccgg cagcgcaggc gcttttaaat atggactcag agacaccagc tgtatttaca
    52801 gcggtaacag atcctgtctc agcaggtctg gttgatacat tagctaagcc tggtgggaat
    52861 atgacaggct ctacagatgc gactgatgtt gagaatcaga ttgatttgtt gaccaaggcg
    52921 ctgcctcaag ctaggacagt tgggattttc tacaattcaa gcgaggtgaa ttcggagata
    52981 caggctaaga aggccaagag ggagcttgag aaaaaaggct taaaggtcct tatgaaaacc
    53041 gtaaccacta ctaatgatgt gcagcaggtt atgacaagct tggctagtca ggttgacgct
    53101 gtttacctgc caacagataa tacggttgcc tcaacagcta ctactattgg ggatatttta
    53161 aaggaggcca aaattccttc aatgggaagc gatgctgctt acctgagtgc tgttttgttc
    53221 acctcaggtg ttgattacca tgctattggc atgcaggctg gtcagcaggc ggtagatatt
    53281 ttaaagggta aaaaaccagc aagcattcag gttgctaagc ctcaaaaggc aagcattgct
    53341 gttaatgatg atatggcaag acttctgggc attgaccccg aggtgatcaa ggctcttgca
    53401 agtaacggag ccaactagcg ttttaggagg aaggtatgaa aaaaggaagc tatttaatac
    53461 tgttagtgct tgcaggcttc gttttggtgg cttgtcgttc gacagctagt cctcgtaagg
    53521 ttaaccaatc tcatgttaac atcggtattt tacaatacat ggaacatgat tcgctgacgg
    53581 cagctcgtcg aggctttgaa gcgcaattaa aggcagcggg ctatactaag ggagacaagc
    53641 tgagccttca ttatcaaaat gcacagggcg accaagctaa tttacagacg atttcagagc
    53701 agctagtgaa gcaaaatgat ttgatcttgg cgattgcgac accggcagcg caagccttag
    53761 cgaccgtctc atcagataga ccaattgttt ttacagcagt aacagatcct atctcagcag
    53821 gcttagtgga taggatcaaa aagcctggtg gcttgataac aggaacaagt gaccaggcgc
    53881 cgattgcaaa gcaaattgac ttgttagccc aagccttgcc agaggccaaa actattggca
    53941 ttttatacac agctagtgaa cgtaatgctg aggtgcaggt aaaggaagct gaaacgctac
    54001 tgaccaaggt tggttatagg gttattaaaa agggaattgc cacttcaaat gatgtgcaag
    54061 atactgctgc aagcttgatg agagcagtag acgcgctttt tgtaccgaca gataataccg
    54121 ttgcttcaac catgacaatg ctgggtgagc tgtcattggc taataaggtt ccaattattg
    54181 gtggctcaac ggatatggtt gatgcaggtg ggctcttgac ctatggtatc gactacgaga
    54241 gccttggtag acaggctgga gaaatggcca ttaagatttt aagaggacag gatccagcaa
    54301 gcctagcagt ggagtaccca aaaacagtca agctacatat caatcaagca atggcagaca
    54361 agctagcgat tgatacttcc acattatcag ttgactaaat tgctaggtta aaggctaaat
    54421 gactgatctc tagccagctg gctaaatgac aaagtcttaa ccagttagct tagcttacta
    54481 ttaacgattc atatgacaaa aaaggagaaa tcatgtcact cattttatcg agcttatcac
    54541 agggcttatt gtggtctatt atggcaattg gtgtttacct gacatttcgt attttagata
    54601 ttgccgattt aactgcagaa ggttcctatc cgcttggggc agctatttgt gcaacgggta
    54661 ttgtatcagg tgtttctccc ttgctggcta cgtttttagc ttttattgga ggcttgctgg
    54721 caggccttgt ctcaggatta gttcacacca aattaaaaat accagcctta ctaacaggaa
    54781 ttatcactct gacaggcttg tattctgtga atctaaaggt gctaggaaga gccaatgtgg
    54841 ctttattacg tcaaagaact ttagttaccc agctctatga tctaggcttt accaagcttg
    54901 cagcggtgct aattatgggc tttgtctttg tgaccattgt gattttttta ttagccctgc
    54961 tgatgaaaac tcagcttggc ctagctctgc gatcgaccgg agacaataat ccaatgagtg
    55021 aagccaatgg tatcaaaaca gatcagatga aaatcatggg gtatatgcta tctaacggtt
    55081 tgattgccct atgtggtgcc ttgctttgtc agaataatgg ctatgcagat ttaaatgctg
    55141 gtgttgggac aattgttatt gggctggctt cgattatcat tgctgaggtg atgattaggc
    55201 agctaagcat tggctggcgc ttagcttcca ttgttttagg ctctattgtt tatcgcttaa
    55261 ttattctagc tatcctagcc attcccggta tggatgcaga tttggttaag cttttttcag
    55321 ccatgctatt ggcagctgtt ctttttgtgc cagaattaca gcaaaggctt cgccttcgaa
    55381 aaacaagttt aggataggag aaatcatgtc agcaatatta tcaattaagg ctattcacaa
    55441 aacatttgaa gcaggtacga ttaacgaaaa tcatgtcttg agaggcttat ctttggacat
    55501 tgaggagggg gattttatct cggttatcgg tgggaatggc gctggaaaat ccacattaat
    55561 gaatactcta gcaggcactc tggcttttga tcagggcgat attcttttag agggaaaatc
    55621 aatcaagcat ttatcagccg ctaagcgtgc caaggacatc agtcgagtgt ttcaagaccc
    55681 taagatggga accgcttcac gcttgaccat tgaggaaaat atggctattg cttaccgccg
    55741 agggaaatca agggggctag gctggggcgt taaagaaaga gagcgccaga tctatcgtca
    55801 ggccttgcag gaattaggcc taaatctgga aaaccgtctt aaggccgaga cacagttttt
    55861 atcaggaggg caaagacaag ccttgaccct gttaatggct tccttagcaa agcctaaggt
    55921 cttgttgcta gatgagcata ccgcagctct tgatcctaag accagtacaa tggtaatggc
    55981 tttgacaaag cagcttgttg agacacatgg cttgacaacc ctgatgatta cccataattt
    56041 ggaaaatgct attgcttatg gtaatcgtct ggtcatgctc catcaaggta atattgtggt
    56101 ggatattaag agagaagaga aggccaagct gacggttgac cacttgatgg cactctttca
    56161 ccaaaatagt ggtcatacgc tccttgatga tgcacttgtt ttgggatagg ctaggtgagg
    56221 gttagctctg ttttcaaata gcagccataa tgaaaaggct taaagccaac gcttctagaa
    56281 acgctagctc aagccttgtt ataatactta ggagattttt ctaagagtga taaagccatg
    56341 atgacgtcta ttgtagtcaa aggatttgtt tcggatgcga taagcctcat tttccacaat
    56401 ttcaattgcc ttattcagct gctgaatggt aatcgcctca tcaatctcat gaaaagcagt
    56461 gctataataa tcctcactaa cacgttgatt gcggtcttta taggtatttt tatgctctgt
    56521 taaaatggcc ttagcctcag cacgttttgc aatggtatct ataatacctt gaccatatgc
    56581 tctagcctct tgaaggattg acagcatatt gtctagagaa tatgcgtttg ctaagcggct
    56641 gacaaagcta tcagcgacct caggacttaa attaatacca tctaagtgat aaatcatctc
    56701 tgggtgtagc tttaggtaat actgcaattc gcggaacaaa agcgctggaa ttttcgacga
    56761 atccctatat ggattgagct gaatctcctg actatgtagc ctattgataa aatcgtcctt
    56821 gaactgctta atagcatcgt agtctgattt ttctagctct gctttaatat tggctagaat
    56881 ctgggcgtct gaataacgac gatagcttga tagtgaagca gcaggcctac tagtattgga
    56941 atttcgagaa gcttctgctc ttctagtctc tttgcttggt gtttgctgct tatttgactg
    57001 agtctcctgc tcggttagtc gtagctcagg gtgtaaacga ctaatattgt taagaaattg
    57061 gttaacctca tattctgatg aaaactttag cctaggtctg gccttgacct tctcaatagc
    57121 cttgtcaata atccttttcc cgtacctttt gagattactg tcagactgga tcaaataaag
    57181 attaacatgt aagtgatctt gactatccgc cttagataag ctgttaccaa ggccaaggct
    57241 tcctaagagc gtagctagta acagcaggtg ttttactaga ctacgctgaa caatattgtg
    57301 acgactaagc ataagttatt ttcccattct attgtaatat accagaaaat gttatcaaaa
    57361 taaagataag atgtcaatgt cattaatggt ggttaatctt taattaatgg tcgttaatct
    57421 agtatatcag agagctagct taggctggca gtggtcattc tgtgcgtctt ggtacgaaat
    57481 gcccaagcag atgcagctca ctagaatgat caatagcctc aacacaaagc cccttacagc
    57541 ttgacacaag ctgtaagggg ctttgttgta ttaacagata actcaaatcc ttgcttttta
    57601 taataaatct aaggttttta gcttgtcatc aatcatgtgc agaacggttg ccaaatcctc
    57661 tgggttttgc acgaaatcaa gcttgtttcc atcaatcttc atcttaggtg aaacgtcata
    57721 ttgctcatac cagcttgggt attcaccatg tacctgatgg taataggctt ctaagtcagg
    57781 attgtcgtca acctgctcaa aacgtctgcc gcgcttttca atgcgctcta gcatcttctc
    57841 aaaggagaca tcaatataaa tcagcagatc aggccgtttt taaggcattc cttcaagctc
    57901 ctctagcata ttggctaaga gctcttggta aatttcaagc tctgtcttgg taacatttcc
    57961 atttttatag ttaagtgtca agaagagctc atcttcaaag attgagcggt caagaatatt
    58021 attgtctgcc tggtaggctt ctttaataga tttgaagcgc ttgttcaaaa agaaaatttg
    58081 tagtaaaaag gcatattttt tagggtcttg gtaatacaga tcaagaacag gattgttatc
    58141 aacagcctcg taaaatacct ctgttcctaa atgctcaccc agtgcagcag caagggaact
    58201 cttgcctgcg ccgattgttc cagctaatac aatcaacatg tttctccttc tatgtagtct
    58261 tagtgtattt gtgcaaaaat cgtttcaacc tcagctaagg ttttagcgcg tgaaacggca
    58321 ctgcgaattt tggcagcgcc tgctgtccct cgcaggtaat gaggggctaa cccacgaaat
    58381 tcacgaacag caatagcttc tcccttgagc ctgatgaggc gcttgagatg gtctttagca
    58441 atatctagct ttttagcaaa gggcagctct ggcaaaacct ctcctgtctc aaagaagtga
    58501 ttaatttggg tgaagagata agggttgttc atagctgcac ggccaatcat gaccgcatct
    58561 acaccaatct cctcaatcat gaacctagcg tcctgaacag ttctgacatc tccatttcca
    58621 ataaatggaa tcctggtaat agctcttgag acgcgtgcaa gggtttcatg gtcacaggtg
    58681 ccagtataca tctgctcacg agtacggcca tgcatggcaa gagctgacac accagcagct
    58741 tcagcagcca aggcattctc aacagctagt gagctgtctg cccagccggt acgcattttg
    58801 acagtcagtg gaatgtctaa aacagaggtt acctcctgaa tgatatggta aatcttatca
    58861 ggatcgcgaa gccacttggc acctgcttca tttttaacca ccttgttaac aggacagccc
    58921 atattgatgt caacaatgtc agccttggta tggctctgga taaaatcagc cgcacgcttt
    58981 agtccttcag cgtcaccgcc aaatagttgg attgacatgg ggtgctcatt gtcatcaata
    59041 tgaagcatat gcagggtttt ttcgttatta tagagaagtc ccttttcaga aatcatttcc
    59101 atgacaacaa ggcctgcacc aaattccttg gcaatcgtgc gaaaggccga attggtcaca
    59161 ccagccatag gtgcaagcac tgtacggtga gggatttcca catgaccaat cctaaagggt
    59221 gagttaagcc ttgtcattga tcagcacctc caaatcagtt tggtcaaatt ggtacttggt
    59281 gccacaaaat tggcaaacaa tttcagcccc cttatcctcg tttagcattg tcaacaggtc
    59341 agctttaggg aggctcatta gggctgacgc aaagcgctct cttgagcagt cacactgaaa
    59401 gctcagctgc tcttcagcta atcgcttgta aggctcttca ccataaatag ctgctaacag
    59461 agcgtctata tgattttccg acgctagaag ggttgaaatc gcaggcattt cctgaatgcg
    59521 cttctcatag tggctaatct cttcgacaga agctccaggc agcacctgca gcataaagcc
    59581 gccagcaacc ttgaccttgt cctcttgatc tagaagcaca ttaaggccga cagcagatgg
    59641 tgtctgctca gactctgtca agtagtaggc cagatcctca ccaatctcac cggtaatcaa
    59701 gggtgttgta gaggtgtagg gattgcctgt tccatagtcc gtaattgtca caaagtgtcc
    59761 ctgtcccata aaaggaccaa ccagtacttc tccagttgct gtttttttga tatcaacacc
    59821 gggattttga atatagccct tgacatgccc ttttgtgtca gcaacagaaa taatatgccc
    59881 aaaggaggaa tcgccaataa ccttgacagt aaccttacta tctccttttt ggttggcagc
    59941 tagaatctga ttggcaatca aggtacgacc aagtgcaacc gttgaagatg ataaggtatg
    60001 atgcctttcc tgagcatatc gaacagtttc ggtgcaatcc aaaacatagg ccctgaaggc
    60061 accggaggca gaaattgttt taattagttt atccataatt tctattatag cataatgaac
    60121 aaggcttgtg ctggttgctt tagaggaaag ctgcttgaaa atagagaaac actatttggt
    60181 taataatagc agctctataa agccacttaa aaacagagca gtgctaacaa atggtagtat
    60241 tcttgtcctt agcacgcagt aagctaatca cctaagtcag tacaatcaaa caagcatcaa
    60301 aaaacagctc cgataggttg attaaaggaa gaaatgataa aagagttatt tcgtaatgct
    60361 ttgctgataa tgagcaaggt aatcatgtgg tgtcgtatca gtgtactttt tgaaggtttt
    60421 caaaaaatgg gtggtatcgt agaaataaag gagcttagcc acttctccag ctggtactcc
    60481 tcttcgtaaa agtagcttgg cttcttgtac tttttccttc aaaatatagg tctgcaacga
    60541 aatagaagaa tacattttaa aaacagctcg taaatgtgac tctgagatat aaagatgctt
    60601 agcaatatct gataccttta attttgaata aaggtgctta tcgacgtaat ataaaatact
    60661 attataaatt tgctgcttat cagaaacact tttgttagtc aatgattctg agaggctaat
    60721 aatagcagct gctcttattt gaagcacctt aaggagatct gtagcttttt cagttaggtt
    60781 cataaaatgc ttaatgcgct cgtagttttt ggcaacatca gtattttcag taaagcttag
    60841 ttcaagcagc ttaataaaat aaataataga aagatttttt tcagctctta atgcgggaat
    60901 agaagaggag acgacatctg atgaagggat acaattgatt tcgtgcttta atagctctgt
    60961 attacccagc ttgactaaat caataatatg attcaaataa tttaagacag ctggcacatg
    61021 aaatgacggg gtattttcca attcgagatt agctataata tgaggatcct cccagattag
    61081 ctgggcttcc tccagtaaat cattaatgct ttgctggcag ctcatttcaa agttggtgtc
    61141 aaaaaaggca tcaacagcta tcaaaaggct tcgaatatga gaagcaggaa aatgaggaat
    61201 ggtagagata tagccaacta gctctttttt tgacttatca ggatagcgct tcaagaagct
    61261 atcggctaat tcctccttat agctatcctg aaagaaagag gtgtaaaaag gcccaatgaa
    61321 aataaacttg tcaccaatag gaaacattag agaggattcc tcaagcgttc cctcataaca
    61381 agtgagctca gtattactag gaatatctaa tgttttaatt aattcatagt aggggaatcg
    61441 acgctcctcg tcatcataag cctgaaggag ctcaagattt tgagaaagca ctaaaacagg
    61501 taattgtgat aggttatg
//
LOCUS       DARYXZ010000003        59764 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYXZ010000003 DARYXZ010000000
VERSION     DARYXZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59764
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            84..1283
                     /locus_tag="TV186_000123"
                     /pseudo
     CDS             84..1283
                     /locus_tag="TV186_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            1377..1532
                     /locus_tag="TV186_000124"
     CDS             1377..1532
                     /locus_tag="TV186_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1531564.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(1714..2179)
                     /gene="tnpA"
                     /locus_tag="TV186_000125"
                     /pseudo
     CDS             complement(1714..2179)
                     /gene="tnpA"
                     /locus_tag="TV186_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(2466..2939)
                     /gene="tnpA"
                     /locus_tag="TV186_000126"
     CDS             complement(2466..2939)
                     /gene="tnpA"
                     /locus_tag="TV186_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1531565.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            complement(3221..3586)
                     /gene="rplL"
                     /locus_tag="TV186_000127"
     CDS             complement(3221..3586)
                     /gene="rplL"
                     /locus_tag="TV186_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL1531566.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(3651..4151)
                     /locus_tag="TV186_000128"
     CDS             complement(3651..4151)
                     /locus_tag="TV186_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL1531567.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(4180..4315)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(4447..5088)
                     /locus_tag="TV186_000129"
     CDS             complement(4447..5088)
                     /locus_tag="TV186_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL1531568.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(5085..5852)
                     /locus_tag="TV186_000130"
     CDS             complement(5085..5852)
                     /locus_tag="TV186_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL1531569.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(5852..6604)
                     /locus_tag="TV186_000131"
     CDS             complement(5852..6604)
                     /locus_tag="TV186_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL1531570.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(6615..7745)
                     /locus_tag="TV186_000132"
     CDS             complement(6615..7745)
                     /locus_tag="TV186_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL1531571.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(7812..8498)
                     /locus_tag="TV186_000133"
     CDS             complement(7812..8498)
                     /locus_tag="TV186_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1531572.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(8532..9884)
                     /locus_tag="TV186_000134"
     CDS             complement(8532..9884)
                     /locus_tag="TV186_000134"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL1531573.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(9937..10893)
                     /locus_tag="TV186_000135"
     CDS             complement(9937..10893)
                     /locus_tag="TV186_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL1531574.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(10890..11741)
                     /locus_tag="TV186_000136"
     CDS             complement(10890..11741)
                     /locus_tag="TV186_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL1531575.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            11843..13186
                     /locus_tag="TV186_000137"
     CDS             11843..13186
                     /locus_tag="TV186_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL1531576.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            13186..13974
                     /locus_tag="TV186_000138"
     CDS             13186..13974
                     /locus_tag="TV186_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL1531577.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(14598..15587)
                     /locus_tag="TV186_000139"
     CDS             complement(14598..15587)
                     /locus_tag="TV186_000139"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL1531578.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(15829..17598)
                     /gene="lpdA"
                     /locus_tag="TV186_000140"
     CDS             complement(15829..17598)
                     /gene="lpdA"
                     /locus_tag="TV186_000140"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL1531579.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(17807..19216)
                     /locus_tag="TV186_000141"
     CDS             complement(17807..19216)
                     /locus_tag="TV186_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL1531580.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(19340..20338)
                     /locus_tag="TV186_000142"
     CDS             complement(19340..20338)
                     /locus_tag="TV186_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL1531581.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(20418..21386)
                     /locus_tag="TV186_000143"
     CDS             complement(20418..21386)
                     /locus_tag="TV186_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL1531582.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(21892..23802)
                     /locus_tag="TV186_000144"
     CDS             complement(21892..23802)
                     /locus_tag="TV186_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1531583.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(24212..24997)
                     /locus_tag="TV186_000145"
     CDS             complement(24212..24997)
                     /locus_tag="TV186_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL1531584.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(25103..26764)
                     /locus_tag="TV186_000146"
     CDS             complement(25103..26764)
                     /locus_tag="TV186_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1531585.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(26974..27732)
                     /locus_tag="TV186_000147"
     CDS             complement(26974..27732)
                     /locus_tag="TV186_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1531586.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(27729..28598)
                     /locus_tag="TV186_000148"
     CDS             complement(27729..28598)
                     /locus_tag="TV186_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531587.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(28612..29607)
                     /locus_tag="TV186_000149"
     CDS             complement(28612..29607)
                     /locus_tag="TV186_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1531588.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            29959..31629
                     /locus_tag="TV186_000150"
     CDS             29959..31629
                     /locus_tag="TV186_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL1531589.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(31718..32956)
                     /locus_tag="TV186_000151"
     CDS             complement(31718..32956)
                     /locus_tag="TV186_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL1531590.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(32946..34127)
                     /locus_tag="TV186_000152"
     CDS             complement(32946..34127)
                     /locus_tag="TV186_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1531591.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(34190..34666)
                     /locus_tag="TV186_000153"
     CDS             complement(34190..34666)
                     /locus_tag="TV186_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1531592.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(34844..35890)
                     /gene="rfbB"
                     /locus_tag="TV186_000154"
     CDS             complement(34844..35890)
                     /gene="rfbB"
                     /locus_tag="TV186_000154"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL1531593.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(36082..36678)
                     /locus_tag="TV186_000155"
     CDS             complement(36082..36678)
                     /locus_tag="TV186_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL1531594.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(36678..37547)
                     /gene="rfbA"
                     /locus_tag="TV186_000156"
     CDS             complement(36678..37547)
                     /gene="rfbA"
                     /locus_tag="TV186_000156"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL1531595.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(37604..38713)
                     /locus_tag="TV186_000157"
     CDS             complement(37604..38713)
                     /locus_tag="TV186_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL1531596.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(38768..39556)
                     /locus_tag="TV186_000158"
     CDS             complement(38768..39556)
                     /locus_tag="TV186_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL1531597.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(39546..40232)
                     /locus_tag="TV186_000159"
     CDS             complement(39546..40232)
                     /locus_tag="TV186_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL1531598.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(40306..40968)
                     /gene="nth"
                     /locus_tag="TV186_000160"
     CDS             complement(40306..40968)
                     /gene="nth"
                     /locus_tag="TV186_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL1531599.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(40968..41645)
                     /locus_tag="TV186_000161"
     CDS             complement(40968..41645)
                     /locus_tag="TV186_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL1531600.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(41712..42230)
                     /locus_tag="TV186_000162"
     CDS             complement(41712..42230)
                     /locus_tag="TV186_000162"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL1531601.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(42310..42678)
                     /locus_tag="TV186_000163"
     CDS             complement(42310..42678)
                     /locus_tag="TV186_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531602.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(42687..44897)
                     /gene="recJ"
                     /locus_tag="TV186_000164"
     CDS             complement(42687..44897)
                     /gene="recJ"
                     /locus_tag="TV186_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL1531603.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(44894..45658)
                     /locus_tag="TV186_000165"
     CDS             complement(44894..45658)
                     /locus_tag="TV186_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1531604.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(45658..46587)
                     /locus_tag="TV186_000166"
     CDS             complement(45658..46587)
                     /locus_tag="TV186_000166"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL1531605.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(46602..47240)
                     /locus_tag="TV186_000167"
     CDS             complement(46602..47240)
                     /locus_tag="TV186_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL1531606.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(47233..48471)
                     /gene="hflX"
                     /locus_tag="TV186_000168"
     CDS             complement(47233..48471)
                     /gene="hflX"
                     /locus_tag="TV186_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL1531607.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(48556..49446)
                     /gene="miaA"
                     /locus_tag="TV186_000169"
     CDS             complement(48556..49446)
                     /gene="miaA"
                     /locus_tag="TV186_000169"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL1531608.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            49579..49755
                     /locus_tag="TV186_000170"
     CDS             49579..49755
                     /locus_tag="TV186_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL1531609.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(49911..50548)
                     /locus_tag="TV186_000171"
                     /pseudo
     CDS             complement(49911..50548)
                     /locus_tag="TV186_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(50705..52969)
                     /gene="glgP"
                     /locus_tag="TV186_000172"
     CDS             complement(50705..52969)
                     /gene="glgP"
                     /locus_tag="TV186_000172"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL1531610.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMVGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(52995..54497)
                     /gene="malQ"
                     /locus_tag="TV186_000173"
     CDS             complement(52995..54497)
                     /gene="malQ"
                     /locus_tag="TV186_000173"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL1531611.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(54704..55726)
                     /locus_tag="TV186_000174"
     CDS             complement(54704..55726)
                     /locus_tag="TV186_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1531612.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            55973..57226
                     /locus_tag="TV186_000175"
     CDS             55973..57226
                     /locus_tag="TV186_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1531613.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            57526..58887
                     /locus_tag="TV186_000176"
     CDS             57526..58887
                     /locus_tag="TV186_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1531614.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            58887..59723
                     /locus_tag="TV186_000177"
     CDS             58887..59723
                     /locus_tag="TV186_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1531615.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        17474 a        14027 c        11157 g        17106 t
ORIGIN      
        1 cattaacatt attcgtcata tttttacttt cattttcttt tcttggtcaa aaagaagtaa
       61 cggtatcgtc acgaggtgaa attatgccta caaaagtcat tgcatcaata cagtcaacta
      121 gcaacaatgc tatcgttaaa aataatctta aagaaaacca actcgttaaa aaaggaaaac
      181 gtttaatcaa atataaagaa accattgaga gttctcaaaa gaattctcta gaatcacaat
      241 taaatacgtt gaataaacaa aaagttggtt tagagacatt gaaagaaagt ctcaaacaag
      301 gaacgaacct cttaccacaa aatgatgaat ttggtcttgc tgacaccttc aacaacttta
      361 taaatcagtc tcaagagatt aaacttggta tcgctaaaat aaatacagaa gtatccaatc
      421 aatccacact tgcaaataac acccttgctg caattgatac tcaaatcaat actataaacc
      481 agcagatttc agaatatgaa gatcttcgtc aagctatctc aaatcataac acaatcttac
      541 caactggtaa tcctcatcaa gatattctca ataattatct gtctcaatca caagaagaat
      601 aaacttccac gtctaaccag tttatctctc agattaacca gactatttca ggtttagaat
      661 catccctctc tgggcttagc attcaaagag caggtactgg tagtagtgca acatacgata
      721 acagttcaga aaccaaagtt gaagtcttga ggactcaatt tctacagaat gcttcacaac
      781 agctgtcaac catcgacagt caaatcactg aacttaaagc tcagctagaa caagcaagtg
      841 tatagttaga cactaatgtt gttttagcac cagaaaccag gattattcat ctaaataatg
      901 aatacgaggg gaaaagtctt atcccaaatg gtagtgatat tgccaaaatc tatcctaata
      961 ttactcaaac tagaaaagct ctgattacat actttgtaac ttctgattat gtttctctcc
     1021 ttaaaaaagg tcaaactgtt cgtctaaatc ttcaaaaagt gagaaaacag tccatcactg
     1081 ttaatggaaa aatttctact attgataaaa cagcaacaaa aacagaacaa ggtaatcttt
     1141 tcaagattac aactcttgcc aaactccctt ccaaggatag ctacttgata aaatatggtg
     1201 cacagggtcg tgttacaagt gttatcgcta aaaaatccta cttcgacttt tataagaata
     1261 aactgttgtc aaatcatgat taaaccattc cggacgtttc gatgaccatt taggatttag
     1321 agaaataata tattgatctt aaattataat attagaaaaa agaaggaggt ccacaaatgg
     1381 aaaaacaaaa ttcactcact caatttcaag aactaaattc atccgaactc aatcaaataa
     1441 caggtggaga ttggtggtca gagatattaa attttaatcg ctctcaaaaa tataaacata
     1501 cctccgtggg ttctaataat attattgtct aacatatact tagtattgta ataatagttt
     1561 ttttagtaga aatcataacc acccgtccaa caggtggttt gaatagggac tataaaccca
     1621 tataactagc cagcgcctaa agacgctggc tttcactttg ttcaaaccac attgctattg
     1681 actcgtcact tgcctctcaa agaagtattt gtatcactta cccttatctc taaagggatc
     1741 ctcatattct tttacactca gtttatctag tgctatgtca tgtttttctt gttcttgaat
     1801 atattttttt attgtagctt catttaatcc aaccgtacta atataatagc cttctgccca
     1861 aaagtgtcga ttaccaaatt tgtatttcag attggcgtgc ttgtcgaaca tcataagcgt
     1921 actcttacct tttaaatatc ctataaaact tgaaacactt attctgggtg gaatgcttac
     1981 taacacgtgt acgtgatctg gcatcagatg tccttctata tatttctaca cctttatagc
     2041 tacataatct ttgaaaaatt tctcccaaac tgcctcgata ttgattatag attacttttc
     2101 gtctatactt aggggtgaac acaatgtgat atttacaatg ctactttgtg tgcgataaac
     2161 tgtggggctt ttgtgccata tttttactcc tttcgcttta caattggctt gaacacctat
     2221 attgtagcgc gtttggagtt tttttgtagt ataacgttcg atgcgtaccc gcatagcggg
     2281 ggatttttgt ttcgcaccta cggagcgaaa cggactaaag tcactaagtc ataaccacgc
     2341 gtaaaaacgg gtggcttgta caccggctat aagccgtttc tctccagcga cgtctaaaga
     2401 cgttcgctga acttcgttca ggttagtgct atgattactt gactaatgcc cgtaaaaacg
     2461 ggcttttatc ttgttttaaa actgccatct gaaaatggat cttcatattc tttaacactc
     2521 aacttatcaa gtgcaatgtc atttttctcc tgctcgcgaa tatatttcgc taccgtcctt
     2581 ttgttcagtc caacggtact aacatagtag cctctagccc aaaactttcg atttccatac
     2641 ttatatttta aattagcgtg tttatcaaat atcatgagag cacttttact tttcaaatac
     2701 cccatgaaat cggaaatcga aagttttgga ggtagcaaga cgagcatatg aacatgatct
     2761 ggcatcatat gtccctcaat gatttccacg cccttgtatt gacataggtg acggaaaata
     2821 tcaattaagt cctgtctaat tttgtagtaa atggattttc tgcggtactt tggtgtgaaa
     2881 actatgtgat atttgcacat ccatttggta tgtgataaac tgtaactggt tttagccatc
     2941 tctttttcct ccttgatcta acctgaacaa ttagattata acaggaaaaa gaaatggaag
     3001 ctcaaagcct tgtcagccac cagcatagct ggtggttttc ttgtttttct ctacgagaaa
     3061 aactggctcg aagccataat aaaaataaaa accctgccaa aaaatctttg gtagggtttt
     3121 tagcaggaaa ccaaatcaat ttatcagttt ctctaaatcg ctctaagcaa tcattaaacc
     3181 ttgatttact aggcttccgc aatcaaattg cgatactcta ttatttaaga gtgatagttg
     3241 ctccagcttc ttcaagctta gctttgattt cttctgcttc tgctgctgca acaccttctt
     3301 tgatgttagc aggtgcgccg tcaacaagac ctttagcttc tttaagtcca agacctgtga
     3361 tttcacgaac tgccttgata acaccaactt ttttgtcacc agcagatgtc aactcaacgt
     3421 caaatgaatc cttagtagct tcttcagcac caccagcagc agctacagct acaggagcag
     3481 ctgcagtcac accgaattct tcttcgatag cttttacaag atcgttaagc tcaaggattg
     3541 aagcttcttt aatttcagca ataatgtttt caatgtttaa tgccattgtc atttcctcca
     3601 aatagttata ttaaataatg atttgtagct ctaggctacc tctaaaggcc ttacgcagcg
     3661 ccttctttgc tttctgcaac agccttgaca gcgtatgcaa cgttgcggac tggagcttga
     3721 agtacagaaa gaagcataga aagcattcct tcgcggtttg gcaatgctgc aagtgcttga
     3781 atttcctctt ttgaagaaac aacaccttcg atagcaccac ctttaatctc aagtgcttca
     3841 gcagttttag caaagtcgtt gatgacttta gctggtgcga taacatcttc atttgaaaat
     3901 gctactgcag atggtcctac gaatatatct tttagctcgt caagacctgc tttttcagct
     3961 gcacgagtca agattgagtt tttgataacc ttgaactcaa cgccactttc acgaagtgaa
     4021 cgacgaagaa cagtatcttg atcaactgta agaccacgtg aatctacaac aacgatactt
     4081 acagctgctt tcattttctc agcgataagc tcaacttgtt cagctttttt agcgataatt
     4141 gcttcactca ttagttttac ctccgttttt atttttgggc taggcacaaa aaaatcgcac
     4201 ctaaacctag acacgaaagt acaaatacgt tatcttcaat aatgacgttt tgtgcctcgg
     4261 caggaatatt atgagcacgc tcccctgctg tcttaggtca gttttattca aaaccatagt
     4321 tagtatagcc tttttaaatg actttgtcaa cctatttttt agaaaatctt aaataaaaaa
     4381 ggaaagctct tggctttccg ctaaatagat ctgattagtg gctcaaaagc gcctcctaac
     4441 ttaagcctaa tgataagcaa cttgtgacga ttgattgcta taacttagcc cgatcaagct
     4501 ccacagtatc atctcataaa taaagaagaa caaggcaaag caatgcccaa aaaaggcctc
     4561 tggcaaaatc caaatgacag gatctgtcag cggatcaaac aaccagcttg aatctcctac
     4621 aaagagaatt tgatgaaaaa gggtaaagaa ctgatcaaag ccaatcatta aagcaaagca
     4681 agcaatcaca attggcaata aggctgctgc tattagccct cttcgaagca gcataaccct
     4741 tccttttttg atgctctgat aaaaatagat aatggttggc aacataagca ggctaaagat
     4801 cagctgtgtt atatgaaaca gcattttcac atctgtaaaa tgctttagac cagctcttga
     4861 tgctgaaaag ctggctagct ttagctcacg aacaaaagga ttggttaagt aagtcagcaa
     4921 tatattatag ttgtggagaa tagacttttt gcacatcaaa actgcctgct ctagttgcaa
     4981 ataatcaacc tcaatcggat aaagcagcca agataaatag atagttatca aaactgccag
     5041 tgctagtagc caaagccaac tggcaatgaa cttgcctttt tcaatcataa tagctcccac
     5101 tcatctaagc tagccaagac atgatcaggc ttaattggaa ggcttggaac ctcttttgcc
     5161 tttgtaaagc cggttgttac tagaatagtt gccatatcat tttgaattcc tgccatgata
     5221 tctgtcaggt aattgtctcc aaccatagcc acctcagaac gtggtacctt taagatctct
     5281 agggctttat tcatgataat cgcatttggc tttcctataa atactggctt cactctagtt
     5341 gctgcctcaa ggagcgcatt taaagcgcca gcacctggca ttagcccacg ctctgttgga
     5401 atatttaagt caggattggt cccaataaac aaggctcctt tttgaatggc aagtgttgca
     5461 attgataaca tttcataggt aacctcagta tctaagccaa caacaacata ggctggattt
     5521 tctgtatcct cggtatagcc tgcctctgca atggcagact ttaagccagt ctcgccaatc
     5581 acataggctg ttttgcctcg attcatatca ttcatgtaat caacggttgc cattgtagcg
     5641 gtgtaaatgg tttcaagacc tgtatgaacg ttaaattgat tggctagcat ttcctgaacc
     5701 atttcaggtg ttcttgtggt gttgttggta actaagagat aagggatacc tttttcctgt
     5761 aaacgcttga taaagcgctc accagccggg atacgatttt tcccttgata gatggttcca
     5821 tctaaatcaa ttaaataagc tttatagggc actaatttgt ctcactttct ttagtcgtta
     5881 taggctgcca tttgataatg gcctgcgcat taagctggcc tgatgacctg atctcatggt
     5941 aggaggtcaa atgctctaga tgatagcctg aggttatttg agtgctgggc ctcacctctt
     6001 tgatataggt caaggtaagg tggcaaggtc tgtggtgtaa taaaaattca tatcccaaaa
     6061 cgtcatacat ccaatccaaa tacttactat tattggcatg accattcata tcaatgtcaa
     6121 aataacgaac ctgataagct tgaaccatag gatcctgaag ctcatctatt ttgataggac
     6181 gcttgatttt cttaacaaag tcagcctgat aaggcaccac caaatcatct ggtatcgcag
     6241 ctgccttacg tgtttgagga tttagcaggg caaaatgaga taaaatggtc atgatggcat
     6301 gacctgcctg atcataaatg tgaaattgcc ggtaacaaaa taatttattg taagaaatag
     6361 cttgcgtttc aatggttact gtttccccaa accttggcat acgatcaatc gttacatcat
     6421 aatccgtaac aacccaaatc aagccatatt gctgaagtaa cacctcattg cctcgtccaa
     6481 tttcagctga ttgtcttgct gataccatta agcaatgtgc taataaaagg ggcagcttga
     6541 catcagcctt aacatcacaa aaatcaaaag acagcttaag gctttcgcta taccttaatc
     6601 ccataacaca cctcctaatc taagatgaat ttttcagcga cagaatcacc taaaaagagg
     6661 ccttttttgg tcattctgat aaagtccttg tcctctacca aaagcccctg attctgaagc
     6721 tctctcacaa caggaccata gcgtgactca aatgataggc caaatttttc ttgaaaccga
     6781 ctgactgata ctcctgattt ttttcgcaga ccaagaaaaa gctcctcctc catcatctcc
     6841 tccttggtga gcacttcctc acttaaccta gcatttccat ctgctactgc ctttaggtaa
     6901 tgctgaatag gaacccggtt gcggtaacga atcccatcaa gatagccaga agcccctgcg
     6961 ccacagccaa aatactcatc attattccaa tacatcagat tgtgcctgct ttcaaagcca
     7021 ggcttagtaa aattagaaat ttcgtaatgc tcaaagccac tggcttccat ttcagaaata
     7081 atatactcaa acatctcagc ttccaaatcc tcagtgggca aatggagctt gccacgacgc
     7141 attttgttca taaaaacagt gtgatgctct aggataaggc tatacaggct aaggtgagga
     7201 atatctaaag caagtgcctt agccacattt tccttgacct gctgcatggt ctgtccaggc
     7261 aaagcataaa tgagatcgat agacatattt tgaaagcctg cctccttaag actagcaatg
     7321 gtcgtataaa tctgagcctc agtatgactg cgtccaatct gctttaattg cttgtcatta
     7381 aaagtttgaa cgcctaggga aatccgattg acagccgatt gccttaatac tgcaatctta
     7441 tcctcagtca aatcacctgg attggcctcg atggtaaatt cttcaagctg gtctagctgt
     7501 aggtgctgct gcaaatggct cagcaaataa tcaagctgat tggctgttat ggctgttggt
     7561 gttccaccgc caatataaag tgtcttcaag gagctgatct gataggattc aaattcctta
     7621 atcagtgcct ctaggtaggc atcgacaggc tgatttttga taaatacctt agaaaaatca
     7681 caatagtagc aaatttgtgt gcaaaaagga atatgcacat aggctgaggt tggttttttt
     7741 gacatggtaa tattatatca ttttagctca gaaattcatg ccaagtgatt agctttttga
     7801 catgtactaa cctaaggctg cttctttttc tccattctca caaaggaatg actactccca
     7861 ttagcatact gctcaaagct tgaggttggc tgatagccca ttttttggta gaggctttgt
     7921 gcgcctttat taaagctagc gacatttaaa acataggttt cttgcggata agtagtgcta
     7981 gcaaaggctt caatgctgcc caaaaaagaa acaccatctt cctgaccagt agtatcaggg
     8041 gccataccaa gaccaatctc aagctctgat tcctgttcaa aaaagctggc aaagccaaaa
     8101 agaacaccat tgcgaagcac ttgaaagtaa tgctctccac gcgccttggg tgacaatatt
     8161 gactgatagt cctcaggatc agcagtcatg ctatagcact cataagctgg gctatagatc
     8221 cagtcatgcg caatgatttc agcactatgc tgtgtcatcg gcatcaggta aaaagaagac
     8281 tcagacaata agcgatgaaa ggtcttgttg atatgcttta tgcgacgccg ctgcacatca
     8341 ggctgatctg tttgataaat gtaattagca tagccctcct gatattctgg aatcattgtc
     8401 aaatacagct tttgggtcaa ctcatcaagc tgactagcaa tcctatccac tctatgcttt
     8461 atcatattac ctccaattct aatgctgctt gatagcataa aaagtgccga agcaacgaca
     8521 ctttttctag attaatcaag gccaatttcc gcacgaacaa ccgctgcaat ggtatcaaca
     8581 taatagtcaa cttcttcatt gcttggtgcc tctgccatca cacgcaacaa tggctctgtg
     8641 ccgctaggcc ttaccaaaat gcgaccatta ccagccattt ctccttccat ctgagcaata
     8701 acctcagcaa tagcaggcac ttccatagca cgctccttca tgctgttgtc aacacgaata
     8761 ttaacaagct tttgtgggta aatagtgacc tcactggcca attcggagag agttttacct
     8821 gtctccttca tgattttggt gagctgaaca gctgtcagtt gaccatcacc agttgtattg
     8881 taatccatga taatgacatg ccctgattgc tcaccaccaa gattgtagcc gaactgacgc
     8941 atctcctcaa caacgtaacg atcaccaaca gctgttacct tcttatgaat gccacagcta
     9001 tctaatgcct tgtgaaaacc aaggttagac atcactgttg tcacaatcgt atttttagct
     9061 agcaagccct tctcagaaag atacttgcct atgataaaca tgatcttgtc gccatcaaca
     9121 atagcaccat tttcatcaac agcaattaaa cgatcactat cgccatcaaa agccaatcca
     9181 atatcagagg ctgtttctgt caccaagtcc tgaagctttt cagggtgtgt agagccgata
     9241 ccatcattaa tgtttaatcc atttggattc tcaccaataa ctgtaatgtc tgcatttaaa
     9301 tctaaaaaga cattacgagc tgaaacagaa gctgcaccgt tagcagtatc aagagctatc
     9361 tttaaaccgt ctaaatctgc tccagtagta accaagaatc tctcgtactt gcgcaagcct
     9421 tctggataat caaccaaggc tcctaagccc tccgcacttg gacgtggtag gaggtcctct
     9481 ttggcatcta agagcgcttc gatttctagc tcttgctcat cagccaattt aaagccatca
     9541 ctcccaaaaa acttaatgcc attgtcaaga gcaggattgt gactagctga aatcatgaca
     9601 ccagcactag ccttttctgt acggaccaaa taggacacac caggagttgc aagaacacca
     9661 agcttataga cctctatccc aacagaaagc aagccagcaa tcagggctgc ctctagcatt
     9721 tcaccagaga tacgggtgtc acgagcgaca aaaactctag gcctttcagt ctcatgctga
     9781 cttagcacat aaccaccgaa ccgaccaagc ttaaaagcaa gctctggggt caactctaca
     9841 ttagcctcgc ctcgaacacc atccgttcca aaatattttc ccataattta tatcagctaa
     9901 acgcttcctc cattccattt tcctagctat tatgctttat tttttaattg ttgtcaactg
     9961 aacggttact accgaaggct ctatagaaac ctgatttgaa accaagctga ccgttttgct
    10021 cgtgtttttg gtgacgtcag aaatattgac ctctgccacc acctcatcaa tagtttcaag
    10081 gacctcccga ctaccagaaa taacagcggt ctgcttggag agcttatact ggatatctga
    10141 cagactgtca tccattagtc caactgcctc gactcgaata ggaactgatt tggtgatttt
    10201 tttgacagaa actgacaaat tagccttggc tggatcgatc gcactagcta aaatggtacc
    10261 atcggcagct actgcctgca gggttactcg gctgctataa ttagcatcta gcacctgatc
    10321 atcaggtaat ttagcgacaa catgatctat caaggcaata gtagactcat cacttgtgac
    10381 ctcaaccttg tcaatacctg tttcaatttt gctaatctca tagcccttag ccagctgctt
    10441 actatcgacg ctgccacgca ccggaaaggt ctttgttttc ttatttccaa tcgttaccga
    10501 aatcttatca ggagaaacag ttgctgtcac accagtaggt agattgataa cctttagggt
    10561 caccgttgca gtacctggct tactctttgt tagatcagct acgatcttaa agcttctagt
    10621 gtcactgttt acctctgaat ccagctttat gcggttggta gaggtcagat aaacctctgc
    10681 accgtaagaa tagccgctga tgaagtactg atcactatca tacttgatat caataggaac
    10741 gtcctttaag ctatgggtgt aggtttcaat agggctataa atttgagaat tagaatgatt
    10801 atgactgcta gaagcagcgg tcaaaaaaag aataatcgca aaaaagattg acactaagcc
    10861 cagcccaaga cgactattta aaaacctctt catttagctt tgcctcctaa gattttttta
    10921 taccaaggta atgtcgcacc gggctcattc atcaaatgag tcttgagaac cgcctcaagc
    10981 tcttctgttg aaaggtcgtg taaaaattga cccttacgag cgatagagac agctcctgtc
    11041 tcctcagaaa caattatcgt tacagcatca gaattttctg aaagtccaat tgctgctctg
    11101 tgacgtgttc caaattcttt ggaaatcgac attgattcag acaaggggag ataagcacag
    11161 gctgcagcaa ttttattgtt agccacaatg accgcaccat catgcagcgg tgtgtttggg
    11221 ataaagatat tgatcaatag ctgactagaa atatcagcat ttaggggaat tcctgttgcg
    11281 atatattcct gcaaggtctg cgtttgctca atagcaatca gagcaccaat cttccgcggt
    11341 cccatataag caactgattt taagagcgca tcaaccagca tctcctcatc actcaagctt
    11401 tgcttttgca aaaatacctg tgttgatcgg ccaaattttt caagccccgc tcgaatttcc
    11461 ggagcaaaaa tcaccacacc tgcaatcact ccataggtga tgacctgatt catcagatag
    11521 gttatagtcg taaaccctat ccactcggca atcacacgaa tgatgataaa gaatataacc
    11581 ccttgtacca aggacatgat cttagttcct gccaaggatt taataaaacg gtaaatcaaa
    11641 taggctacta ttaaaatatc cagcaaatga accaccaaca tcaaggggtc atcaatcagg
    11701 cttagtaaaa attttgtgtc aatacttgat aaattactca tacaattctc atttctatgt
    11761 cagatagata cctctaacat tatatcacgt ttcaagatgt tttccctatc taaaatttaa
    11821 gaacttatgt taaaatatta acatgaaact aaagacacta ctcgctatag cagccggaag
    11881 gactgcgcag ctcattttaa ataaaatcgg aagaggctca acctaccccg gacgattggc
    11941 cttgatgtgg gataaggata ttttagacac acttgccaag gactatgaga ttgttgttgt
    12001 gacagggaca aatgggaaaa ccttaaccac agctctaact gttggtatcc taaaagaagc
    12061 ctttggtgag gttttgacta atccaagtgg cgccaacatg atgacaggga ttacctctgc
    12121 ctttttatct gctaaaagaa aaaaaacagg caagcctatt gccgtcttag agattgatga
    12181 ggcaagcctt gcaagggtaa caacatacat taagccaagt ctttttgttt acactaatat
    12241 ctttcgagac cagatggatc gctacggtga gatttacacc acctatcaga tgattgttga
    12301 tggtgctagt caagcgccga aggcaaccat tctagctaac ggtgatagcc ctatctttgc
    12361 ctcaaaggac ctggttaatc ctgttaaata ttatggcttt gacacaccta agcatgagcc
    12421 acgcctagct cactacaaca ctgaaggcat tttgtgccca aaatgtgaac agattctccg
    12481 ttatcgtctc aacacctatg ctaatctagg agactatacc tgcttaaatt gtgatttcca
    12541 aaggcctaag ttggattaca agctaacgca attaaccagc attacccatc atagctcagc
    12601 ctttgtgatt gacgatcaga cttatcgcat aaatgttgga ggactctata acatctataa
    12661 tgccctcgca gctgttgctg ttgctgagtt ttttggcatt tctgctgatc agattaaggc
    12721 tggcttcaat aaaagcaagg ctgtttttgg tcgtcaggaa accttctcca tcaacggtaa
    12781 agcctgtacg ctggttctca ttaaaaaccc tgtgggtgct agtcaggcac tagaaatgct
    12841 gcgcctagcc gattatccct ttagcctatc tgtgctttta aatgctgatt atgctgacgg
    12901 tattgacaca agctggattt gggatgctga ttttgaattg attaatcaaa tggacattac
    12961 tgagatcaac gccggtgggg ttcggcattc tgaaattgca agacgcttac gagtgacagg
    13021 ctttgatgag gctaaaatca catcattcga taagcttgaa ggtatcatgc aagccattga
    13081 aaaccaagag gctgagcatg cctatatcct agcgacctat actgctatgc tagcatttcg
    13141 tgagctgctt gccagccgcc acattgtcga aaaggagatg atctaatgac ctatacctcg
    13201 ctacaatctc cggaaaatcg cgattatcaa tacgaccttc atattgctca cctttatggt
    13261 aatttgatga atacctatgg cgataacggc aatgtcttga tgttgaagta tgtcgctgaa
    13321 aagctaggcg ctaaggttag agttgatatt gtatccattg gggatacctt tgaccaagat
    13381 gattatgaca ttgttttctt tggtggtggt caagattatg agcaagccat tgttgctaga
    13441 gatttgccat caaaaaaaga ggccttagca gcctatattc accaaaataa ggtactcctt
    13501 gccatttgtg gtggctttca gctgctggga cagtactata ttcaagccaa tggccttaaa
    13561 atcaatggca ttggggttat gggacattat accttaaacc aagataataa ccgctttatc
    13621 ggaggcatta aaattcacaa tgatgacttt gacgaaacct actatggctt tgaaaatcat
    13681 caaggacgga cctttttatc tgacgatgaa aagcctcttg gacgtgtcat ttatggaaat
    13741 ggtaataata aagaggacca aactgagggc gtccactata aaaacgttta cggcagctac
    13801 tttcatggac caatcctttc gcgtaatgtc agcctggcct atcgcctagt cacaactgct
    13861 ctcaaagaaa aatatggctc gactgtttcc ttagcggcct atgataagat cttacagcat
    13921 gagacctcag aggaatacgc tgatgttaaa agcaaggcta gctttgacag ttaagtcctt
    13981 ctcatagcct gattaaacca caacagacat gcaaaacagt tattcccgaa tgaaaatata
    14041 gatttaaata gacaccctca atgtttttcc tatcataaaa tccataaaag ataagacata
    14101 ttcttgcaat aactgaacat tgaaagacag aaagctttct gtccttacta aacatctttc
    14161 atgcgtctgt cgtgctgatc aagcgagata accccaaaaa agtgctagca cagtaacaaa
    14221 atggctatga ccatatgtct gtgcagctct actgtcactg catagacagg ctagagggga
    14281 cgccctactt ggttcagcga tctaggggta ggtctagctt gtttgtgctg agtctgtttc
    14341 ggtagcaaag attgaatcct gctataagat actctcaaaa agattaaccc aaaagccttg
    14401 caacacattt aacgttttta gggataagta ccgatatgca gacacatagc aggagatcta
    14461 tgtgtctggt accaaaggac acaaaaaact aaagtaacac actaaaagcc acatgatacc
    14521 catttgatag ggggcgtcat gtggcttttt tctatctcac tgttcattac aaaaagccaa
    14581 accagcttct ttttgcatta ggcaacaatg gcctttgcca cctcttctac tgtcatacgt
    14641 gagaaatatt gtgttgtatc aatggtttga agacgctcaa gcacatcagc atactcgtat
    14701 ttgcaaccaa tgagtaggct ttcaatatcc tgcacgtcct taataccaaa gaaatcaccg
    14761 tagatcttaa gattcttaat aacagaattt tcaacattag caaaggttga gattttaccg
    14821 gcagggtagc gaacattacg ttcaatcgtg tattcaggtg cctttccata ggtccaatcc
    14881 cagctcccaa attgctcctc agccgattgt tgaatcttag ccagctcgtc ctctgacaag
    14941 acgtattctg tcatgtctgg ataggtctcc ttcattttaa ccaaaatctt gtctgaaaat
    15001 gcttctacgc tgattttttc tggcagctca tttaaaatat tggtcacgcg ggctcgtaca
    15061 gatttgactc ctttggactc aatcttatcc ttactgacct tgagcgcatc accaagaaca
    15121 gtcatatcca catcaaacaa gagacagcca tgatgcatca tacgtccctt ataataggct
    15181 tgagcattgc cacagatttt cttgccatca atttcaatgt cattgcgacc tgtaaaatta
    15241 gccttaactc ctaaatcagc caaggtctca ataactggct gtgagaaggt tttaaaatca
    15301 aaggctcctt ctgttgtttt attggaaata atcgtgtagt taaggttatt gagatcatgg
    15361 taaactgcac caccgccaga caagcgacga accacatgaa taccatgctg ttcgatgtac
    15421 tccttgttga tttcctgaat ggtattttga tgcttaccaa taataatagc cggctcattg
    15481 atccagagga taaacaattc atcctcatca accaattctc taaaggcata agcctctaga
    15541 gcaatgttaa aggcagggtt gtggctctta ttaacaatgt atttcatttc tatctcctat
    15601 agcgataatc gttatcatat tctattcttt attctaatgg aaactcttac aaaagacaag
    15661 ctaaaagagg ctagcaaaag caagggaact agtaaatgct tcctcaatca agaaccatct
    15721 gcaagctagc agtaaagctt gatctaactt aaagagcctt ccttgtatca acgaaagagc
    15781 tgagaaatct ttttcccagc ccttttttat cgcagctata tagctagctt attttttacg
    15841 ttttggtggg ttatgaatgg cttcgccaag cacatctgca aaggcttcgt acatcacctc
    15901 tgagaaggtt gggtgtccat gaattgacaa tagcaattca tcaactgtta gctcagcctc
    15961 catgattgtg gctgcttcat tgatcatttc agcggctgct ggaccaatga tgtgaacacc
    16021 aagtatttca tggtatttag catctgcaat aacctttaca aagccatgag cctcgtttga
    16081 cgcaatagca cgaccatttc ctgtaaagct atttttacca ataagaacat cgccatattg
    16141 ctcacgagcc tgctcttcag ttaaaccaac catagcgacc tcagggtgag tatagaccgc
    16201 cgctggagtg tattttaggt tagccttacg tgttgtgctg ccatgcatgg cattctcagc
    16261 agccacctca cccatacggt aagcagcgtg ggcaagcatt ttagtgccgt taacatcacc
    16321 cggtgcataa atgcctggga ttgacgtttc ttggtagtca ttaaccttaa tgcggttacg
    16381 gtccatttca aggttgaggt tttcaagacc attcatctgt ggcacacgtc caatagatag
    16441 caaggccttt tcagcaacaa cctcttcgcc attattaagc ttcaaggtca actggttgtt
    16501 ggcttcaaca atctcagaga caccaactga ggtctttatt gtcatgcctt tcttagaaag
    16561 gattttttga agctccagtg aaacctcctt gtccatggca ggaataatgc ggtcagccat
    16621 ttcaataact gtaacctcta caccgtaaga ggcccaaaca agaccaagct caataccaac
    16681 aacaccaccg cccataacag caagtgattt cggcatttca cgcaaatcaa gaatatcatc
    16741 agatgtcaag acaagcttag aatcaatccc tggaatattg atgcgtgaga ccttagagcc
    16801 tgtcgcaaga ataatattgc gccctttaat ggtttgcaca ccaatggtaa ccgttttatc
    16861 aggatttacc tgaccaaggc cattaaagat ggttaccttg ttggctttaa gaagcccttg
    16921 aaccccacct gttagcgtct taacaaccgt atttttaaag tcaactgtct tatccatgtc
    16981 aatagtatag ttggttgaag caaggttaat cccgcgtcct gctgcaatct tgatgccatc
    17041 aaggatttca gcatttttga ggtaggtttt tgttgggata cagccaacgt ttaagcaggt
    17101 accgccaaat tcagattttt caacgatagc aatcttgccg cccagctgag caccacgaat
    17161 agcagcgtag taacccgcag gaccgccacc gacaacaatg atgtcatatt catcagcagc
    17221 aagctctgcc tttggtgctg atggcgctga tccttgatcc ggtgcctttg gcacctcaag
    17281 accagccgcc tgtaaatcct cggttgtacg cgcaacattg acatcagccg ctgctgggct
    17341 tgatacatcg atagcttcac ccgcagctcc aatgtagccg ataacttcgg ttacagggac
    17401 tgtctcacct gcctggcgaa tgatttttaa aagcacacct gagtcttctg cttctaattc
    17461 catattggtc ttgtctgaca tgatttccag aagaatgtca ccctcgctga cagtgtcacc
    17521 ctcctgcttt ttccactcga tgatctcgcc ttcttgcatg tcaacaccga gctttggcat
    17581 aataatttca acagccataa tgatattgta aggaacgttc aaatgcaatc agatgcctta
    17641 acaatcagca ctggctaaca taagcctgct aaaagccctg catttagctc atagctagtg
    17701 actacgagct cgttccagat cctttctata gttttaaaga attatctttt cgttactttg
    17761 tttctgaaat atgctctctt tgcatcgcag gccataaggc ctgtcatcag attagcagtt
    17821 caaatggatt ttccatcaat tttttgagat caaccatgaa tttagcacca ttcatgccgt
    17881 ccaccagacg gtggtcaatt gtcagacaca ttgccatgat tggacgtgca acaatctcac
    17941 catcgaccac tgttggggtt ggaatggttg ccccaatacc tagaatagct gaattaggct
    18001 gattgataat tggattgaag gttttggtgc caaacatacc cagatttgtg atggagaagg
    18061 ttgagcctga catttcggta gcctttagct tgcctccttg agcctttttg ataacgtcct
    18121 tagaagcaag gacaaactct gagagactca tcttatctgc accatgaaca actggcacaa
    18181 ctagcccatc atcaagtcct acagcaatac caaggttgac aaagcgatga agctcaatat
    18241 cattagcatc attaatcaat gacgcattca tgtattcgtg ctctggcttc atcaaggtct
    18301 taacaacggc taaaccaatc aagtcagtaa agctaacctt tagccctgtt ttagccatga
    18361 ttgggtcaat cagcttcttg cgcaaggcaa tcatttcggt catgtcaatg tcataattaa
    18421 gcgtaaaggt tggtgctgta aggtaggaat gtgtcatacc ctttgaaata gccttacgca
    18481 tagcagacat cttcttaatt tcaacaccct ctggaagctc cttagcaggc ttttcttcag
    18541 caatagatgc tttttccaca gcaggtgctg ctgcgccaag cacagccaaa atgtcctcct
    18601 tggtaatctt gccaccaata cctgttccga ccaccgctgc aaggtcaact cccttgtcgg
    18661 cagctatctt acgagcaagt ggcgttgcct taggctgagc tcctttgaag ccttcaacgt
    18721 cttctttgtg gatacggccc tttggtcctg ttcctggcac ttggttaagc tcaattccca
    18781 tttctgaagc tgctttacga gctgctggcg ttgcgcgtac cttttctccg aaggctggag
    18841 cattggcaac tgatgctacc tgaggcgctg ttgaggctgc ttctttcggt acagttgttg
    18901 tattagcttc tgctgatgtt ggtactggaa tttcagttgt tttctcactt gaagcagtac
    18961 tattatcaac agattcacct gcagcaccaa tatagccgat aacctcagtg acagggactg
    19021 tttcacctgc ctggcgagtg atttttagaa gcacacctga atcctctgct tcaagctcca
    19081 tatttgtctt gtctgacatg atttcaagaa gaatgtcacc ctcgctaaca gtgtcaccct
    19141 cctgcttttt ccactcgatg atctcgcctt cttgcatgtc aacaccgagc tttggcataa
    19201 taatttcgac agccatatat ttcctttcat ttaatcccgc agcccatgat cttaagacca
    19261 gatacagctg ctgaaaaaag ggatactgtt ttatcagcct gatgaagaaa gcctctaagc
    19321 taagacttcc tttgccatgc taatttccct tgttgaccat ttttacaata gcagccttga
    19381 ttttagcaac atctggtaag atagcttgct caagaacacg tgcataaggt actggtacgt
    19441 cctcactagc aagacgcaca attgggtgat caaggtaatc aaaggcttca ctttcagtga
    19501 ccattgctgc aatctcaccg ataaagccac cagtcttata ggcatcatta acaagcataa
    19561 gcttccctgt cttcttaaca gaattaataa ttaattcctt atctagtggg ataagggtac
    19621 gtggatcaac aacctccaca ttaataccat cagctgcaag ctcttcggct gcctgaagga
    19681 cacgctctag catacgccca taggaaacaa tggttacatc agtcccttca cgcttgatat
    19741 cccccttgcc aagtgggata taaaaatctg gatcctgatt gacctcttct tttttaccgt
    19801 acaaggcctt aggctccatg aaaataacaa tattgttatc acgaatagct gactttaaaa
    19861 gtccctttgc ttcgttagca gttccaggtg caaccacctt gatcccagga atatgcgtca
    19921 accaagcctc aagagattgc gaatgctgag ctgcagatcc aattcctgag ccagaagcaa
    19981 cacgaaaagt tgctggcgtg atcaagccac caccaaacat gtagttgttt tttgccccat
    20041 tattaacaat tgcatcaagt gcaatggtaa taaagtccat aaaagtaagg tcaacaatcg
    20101 gacgaagccc tgtaattgct gaaccaatcg ctgcacctgc aatagcagcc tctgaaatcg
    20161 gcgtatcctt gacacgtttg gcaccaaatt cctcaatcat gccaacagaa gtaccaaagt
    20221 ctcctccgta aacacctacg tcctcaccca taaggtaaat cgtgtcatct ttgcgcatct
    20281 cctctgtcat ggcaagattg atagcctcac gcaaagccat taattttgtt tctgtcatta
    20341 ttatctccta atgtttacaa aatagaattg tcaatgttac tgtgaataga tttttgctcg
    20401 atgtgctagc agatcagcta gtctacccaa acgtcctcaa aggctacaga aatgtctgga
    20461 tctggactat tttgtgcaaa ctcataagcg tcatcaattt cttgcttgac ctgtgcttga
    20521 agcgcatcta attcttcatc tgtagcaatg ccttcacctg ttaggtaagc gcgatactta
    20581 agcattgggt ccttttcctt ccactcatca acctcttctt tggtgcggta tttgccggca
    20641 tcagcagttg aatgaccaaa ccaacggtaa gactcaacct caacaacagc aggaccattg
    20701 ccaccgcgaa catgctcaac agccttactc atggtttcat aaactgccat cacatcgttg
    20761 ccgtcctcac aataaaagcc tggaatacca taagcctcag cacgcgtgta gaggtgaggt
    20821 gtatttgtgg cattgttaat gctcatggaa atcccatagc ggttgttaat gataaagaaa
    20881 atcacaggaa gcttccaagt tgctgccata ttgacagact catggaagga gccctcattt
    20941 gttgcgccat ctccagaaaa ggccacaacg atattgttgg tccccttgta ttgctgtgtc
    21001 aaggcagcac ctaccgcaag ggcatagcca cctccaacga taccatttgt tccatagttt
    21061 cctttttcaa aatcagccaa gtgcattgag ccgccgcgtc cctttgacac acctgttacc
    21121 ttaccggcta gctcagccat cattttattg aggtccatat ctttagcaat agattgccca
    21181 tgcccgcggt ggtttgaaaa aataatatca tcataggtca aatgtgccac agcgccaacg
    21241 tttgctgcct cctcaccaac tgagaagtgt gtcatgccct gcacaaatcc acgacggaca
    21301 agcttattaa tacgtgaatc aaattcacga atacgctcca ttttaaggaa catatctaaa
    21361 tgttgttctt tagaaactgt taccatttcg gcctccatat tatcatatta cttcctaatc
    21421 ataaaacttt tcttcacaat ttgcaaggat tttaatcgct ttctttgtga ctataaaagc
    21481 ttttttaaga cgttttagtt tgtggtttca caagctagat tgttatagca tctgttacat
    21541 ttatatataa cagattgaaa aatgagtcag tgtttattca gggaggtcaa gcacctattg
    21601 actttgatag tcagaaatat catcactctt taagaggaaa ataggctcta aatgacctgt
    21661 ttcttctagc acaatcatga tcacctacca aacgaacgct ttgcttgcct cgctccgata
    21721 gaggcgaaat gaactaaaaa tcgcataact aaaaatgcct gattttacct gaaaatcaga
    21781 catttaaaag ctttaagaca ttagactcag gctctaatta taatcctcta agaaaagcct
    21841 gctaccttgc actacccaag aatagcaagg caatttcatt atctcaccag gctactccag
    21901 ctgtcctgca atgtcctccc actccagcag caaggtctcc tgtttctgat taagctgatc
    21961 caactctttt tgccagtcta tcagttgagt cgtatcattt gatactagca tttgagcttc
    22021 tatagcctta gcctgtgctt ctagcccttc taaggtctgc tcaatctcct caaagcgcct
    22081 tgttaagcga cggtattcct tttggctggc cttttgaagc tgataatcag ttacagcagc
    22141 ttctgctaca tcagtctcta ctacgtgatc tgcagcagct agacgggcta attcctcccg
    22201 ctctgccttt ttttctacat aatagtcgta gtcccccaga tagagtgttg agcctgcttc
    22261 agttatttct aaaaccttag tggccactcg gttgataaaa tacctgtcat gactaacaaa
    22321 caacaaggtc ccatcaaagt caatcaaggc attttctaga acctctttgc tatcaatatc
    22381 caggtggttg gttggctcat ctagaatcag aaaattgtcc tttttcatag ataattttgt
    22441 taagagcagc cgagcctttt cgcccccaga tagcatggcc acagactttt tgacgtcctc
    22501 accagaaaag agaaaggcac ctaagcggct gcggatctca agctcagctg tcgttgggaa
    22561 atcacgccaa agctcctcca atacagaatt actaccagtc agatgagatt gcgtttggtc
    22621 ataatagcct gtttcaacat tagtcccata atggcatgtc cctttaatca aaggaatctc
    22681 tccaataatg gatttgagta gggttgactt gccaatacca tttggcccaa caatagcgat
    22741 tgcatctaac ctacggacat ctagatgaat tggctcagct aaaatatggt cattgtagcc
    22801 aatagcggcg tctgtcacct gcaaaacaac atttcctgag ggcttatcaa tctgaaaagt
    22861 catactagct gatttgcgag agctacttgg cttgtctaag cgttctagct tttctagctg
    22921 cttgcgtctt gcctgagcac gcttggtcgt tgacgctcga acaatgtttt tttggacaaa
    22981 atcctctagc ttagcaatct ctttttgctg cttgtcataa tgcttctctt ctgctgcaag
    23041 cttttcagcc tttaaatcaa taaagcgtga gtaattacca acatagcggt ctaagctatt
    23101 tttagtcaga tcaagtgtga tggttgcgac cttatccaag aaatagcggt catgactgac
    23161 aatgatcaag gctccctgat aatttaccag ataatgctcc agccaggcaa tggtttcaat
    23221 atctaaatgg ttggtcggct catcaagcac caatagctct ggcttttcta gtagcatttt
    23281 tgccagggcc aaacgggtat tttgcccacc agaaagctct gagattttca tttcccacat
    23341 gctttcgtca aacttaaagc catttaaaat agctcgaata tctgactcat aggtgaagcc
    23401 atttcgcaag cgaaagcttt ctgacagccg gtcatagtct gacatgagct ggtccagagc
    23461 ttgccctgat cgactggcca tatcagcctc catttgcctt agtcgctgct catcaaccct
    23521 caattcagca aataccttta gcatttcctg ataaatggtc ttgtcagact caaatcggct
    23581 attttgtgcc aaataagata gggttaagtc cctttttcga ctaacctcac cgctagttgg
    23641 ctcttcttct ccaactaaaa tcttaagaag ggttgatttg ccagcaccat ttggcccaac
    23701 caaggcaatg cgatcacgtt caccaacctg cagcgatagg ttttgaaaaa gcacctctcc
    23761 tgaaaaagag cgctcaatgt tatttccttg taatataatc atacccttat tgtagcaaaa
    23821 aaatgccctt ttggggggca cttttagtta tttttacagg taagataaga ctcatcaaca
    23881 agctaaagac ataagcctta ggctaacatc gcttatcacc cttagtggta tttatctgat
    23941 gagacaaact gctgcttgaa aaaccagtgg gttgacctgt tagcgtatcc aacaatcgca
    24001 ccacctgctc agttatgctt gaaatgctat tagccagtga ggaatcacta tggttcgaat
    24061 aataaatcaa accaaaaata agcaatacca atactattag ggtctgcaaa cagcctctga
    24121 caagctgcca gacaagcttc agcagaagct ttgggaggca taagaggata gtcagtagtt
    24181 ttttcatcgt aataagccta aattctttcg tttaggatag cctttcttcc ttgtggtaag
    24241 caatcggcag ccaatctaat agggcctcta gctgctgatt ccaataatac cattcgtgcc
    24301 tgccatgatc cttacgataa tcaatagtca agccaagcct tctcaactca gcaactgcct
    24361 tttcattggc ttcaaacaaa aagtcctcat agccacacca agcgtatagc tgggtttgac
    24421 catcactttc tgctgctata cttgtcaaat aatgcttttt gatatcagga gcattcaaat
    24481 ctccaaaaac accctgccaa taaggcagct cacctatacc ttgctgtaat agcatttccg
    24541 gcgaaaaatg caaggcccca gaaaaggaag cagcatagga aaagcgattg ctttttaagg
    24601 cccatttaaa ggcaccatag cctcccattg acagcccagc aacaaaggtt ttttcacgct
    24661 tagtggtcat attaggaaag aaagaagcta atagccgagg aagttcctct gcaatagctt
    24721 ggtaataatt cataccgtag gtggtatcgg tataccagcc taaatcagtc gatggcatca
    24781 ccacgattaa attggtatgg cgaagcagcc tttcaatatt agtccgcttt tgccaggaat
    24841 tttcatttcc tcccatacca tgtaacagat aaagaactgg aatatcttgg tagccttgct
    24901 cttctgggct aagctcagac tgatcagggt agatcacctt gacatgtctt tccatagcca
    24961 agatctctga atgatactca atgctaatgc ttgccatcag ctcacctcct ttttaatatc
    25021 accaaagcat aaggaaagcc cactcttaag acctaaaagc cagatcctat ttgaccagct
    25081 tttaggcagg gctgtatctg tattaacgga cctccataac aaccggaaga atagctggcc
    25141 gacgcttggt ctgctcaaat aaaaaccttg agagctcctc tctaacagag cctttcaatt
    25201 cactccaatc aaaatgatcc ccttgcagat aattgccaac tgttgtgttg accaattcag
    25261 cactttctcg taaaatatct ctgctctttt tcacatagac aaatccgcga gtgttgacct
    25321 tagccttaga gataatacgt ttttcctttt tagatactgt gatcgcaaca ataaaaatac
    25381 cgtcctctga taagacctta cggtctctca aaacaatatt gccaacatca ccaatggcat
    25441 ttccatcaat catcacatca ctagcaggaa ccgcaccctc gtgtaagaag ccatcctcat
    25501 caagcaccat gatgtcacca cgcttcataa tatgaatatt ttcaggtagt ataccagcct
    25561 cctcagctaa atgagcatga gcagctagat cgcggtattc accttgaatc gggaacaggt
    25621 attttggttt gacgagatta atcatcagct gcaggtcacg cgcattggca tgtccagaaa
    25681 cacgtaaatg ctgcgtgatg agcttaacag agccacctgc tttatagata aggttttcaa
    25741 cacgagcaac cattgcttcc ttggcagcgc ttggcgttgt gacaatgtaa accagatctc
    25801 cgtccttgat ttgcacgtgg cgatgacgcc ctattgccat tttctgtagg ctattaatcg
    25861 gctcacccat acgtccagcc tccagaacaa tcaattcgtg atcctcaaac ttagacatat
    25921 cctttggctt gattaatagc ttttcatcag caatcactag ctttttaaga cgaagtgctg
    25981 ttctgacaat attttcagcg tcagtacctg tcagtaccac tcgcctgcta taggctgctg
    26041 cagaatcaaa gacctgctgg atacgaacaa gatttgaagc gacagctgca atgataatcc
    26101 gcccgtcggc atgagcaatc accttatcca tctcctcgcc aacctcagct tcgctggcag
    26161 tctgctcatt gcttgtggca ttggccgagt cagctaatag ggctaacacc ccttcttttc
    26221 caatgtctgc caagcgagct aggtctgtct gatagccctc acgcgaagcc tggtcaaact
    26281 tgaaatcacc tgtatagaca atattcccct tatcggttcc aataaccacg cctaaacttt
    26341 caggaataga atgtgttgtc ttaaagaagg aaaccaagcc atctttaaat tcaatttctg
    26401 tgtcactgtc gaccacatgg aaattcttaa atctcttggt gctattattg gccttgacaa
    26461 acaattttgc tagctcgatg gtcaattctg aaccaaatac tggcactgga acctccgcca
    26521 acaggtaagg caaagctccg atagcatcag catgcccatg acttaaaaag actccctgaa
    26581 ccttgtcctt gttttcaatt acataatcaa gacttggaat taccaaatct acacctagct
    26641 gttctgtttc agggtatttc aagccagcat ccaaaatgaa catggaatcg ttaatctcta
    26701 ctagatagaa gtttttcccg tactcacgta cgcctcctaa tgcaataatg tttatatcag
    26761 tcatgatact ccttttttta tattagttat tacaaacggt ccttactggg taagtcgaat
    26821 tactgtcttg cagctaagct gcactctttt acagtatatc atattttagg gcttattacc
    26881 tcaaattgcc ttgagacttt ctcaatcttt tcaatagatt atcaaaaaag ccaagggaag
    26941 gctttcattc caatggcttt tagagtattt attttagtca aaaagctggt aataatcagc
    27001 aatggtcatt tgagattttc tcttctgatc aaggtcttga atgattttac catttttcat
    27061 cacaatcagg cgattaccat agttaagagc gtcctccatg tgatgcgtta tcattaaggc
    27121 tgtcaagcga tccttagcta caaaatcatc agtcaaggcc attaaggctt ggctggtctt
    27181 agggtctagc gctgcagtat gctcatctaa tagtaaaagc tctggtcttt ttagggttgc
    27241 catgagtaag ctaagggcct gtctttgacc gcctgataag agaccagtcg gagtctccag
    27301 atgattttcc aagccatttc caactcgctt gaccaagtca gcaaagtctg ccatataatg
    27361 gctaatcctg cgtgatgaca agcctcgcct ttcccctctt tgccttgcaa tcaaaaggtt
    27421 ttcagctact gtcattcgag gtgctgttcc cattttagga tcctgaaaaa cacgtgatag
    27481 gtagctagct cttttttctg ctggcaggtg cgtcacatca tgccctaaaa gcttaatttg
    27541 acccttgctt aacaatagcg tcccagcaat cacattaaaa agggttgatt taccagcgcc
    27601 attcccacca agaatcgtta aaaaatcatg ctcataaatg gtcaaggaaa catcatctaa
    27661 aatagcctta gtctcatcaa agccattatt gacttcgaca gtagcgtgaa ttaattcaat
    27721 aatttttctc atcgtgataa gctagcctcc ttaataattg ctttttttag cacaggcacc
    27781 atcaggcaaa gtgctaatat aatggcacta aatagcttaa gataatttgt attaaagcca
    27841 agagcaataa ctactgagat taaaaattga tacaggatag aaccaaccac aatggctatc
    27901 aagcgctcaa gcagggttag gcctgtagaa tataaaacct caccaacaat aatactcgca
    27961 aggccaatta caatcacacc aatccccttt gaaacatcag catagccatc ttgctgacta
    28021 accaaggcac cagataaggc tatcaaggca ttagagatcg ctaagcccat aagctccata
    28081 cgatcagtat gaatcccaaa gctcttagcc atatcccgat tatctcctgt ggcaatataa
    28141 gcctgaccaa tattggtgta aagaaaatac attaacaaaa aaatcaccaa tgtagctaca
    28201 accaaaccag ctaccaacac attggtgtca gctgcaaagg gaaggtagtc ctgaatgcgc
    28261 ttgatatcat gcaagcccaa attggccctg cccataacca taagcataat ggaatggcag
    28321 gaggtcatga ctagtatgcc ggcaagaagt gttggtatct ttccttttgt gtataacagg
    28381 cctgtggcga agcctgccaa ggcacccgcc agcatagcag ccagagtagc caggatagga
    28441 tttaaaccga gattgagcag agttactgct acagcacctc ctaaaggaaa ggacccttct
    28501 gttgtcatat ctgggaaatt caatattcta aaggtcaggt aaatccccaa gccaagaatt
    28561 ccccataaca agccttgtga tacagatgaa ataatcatat gaactccttt tctattgctt
    28621 acctgtaagg tcagaacgct tcagcaggtc ttttgagatc ataagaccta aatcccttgc
    28681 tgcctttaga tttaaaaatg gcttaccgtc atcaactacc tcgacaggaa cctctgatac
    28741 ctcttttcca gccataagct gcagcacctg cctagctgtc tcaaccccta attggtattg
    28801 actttgtgaa atagaagcaa gactcccttg ctcaaccatt gtatcaacac ttgagtagac
    28861 cggaagctgt gctgcatttg aggcaacaat caccgctgaa aaagcactgg caatagtatt
    28921 atcctgtggg ataaaaacag catctacctt ctcagtcatc acagacatgg tcgtggtaac
    28981 ctcatttgtt gaggggacag cgtaagctag aacctccaag ccttgctttt ctgcaagagc
    29041 tgtaaagtcc ttgacctgtg atattgaatt gtcctcactg cttgcataaa ggacaccgac
    29101 ccttttgacc tgaggggtca tctccttgat cagatcaacc gtctgtcgaa caggaacctt
    29161 atttgataag ccagtaacat ttgcctcagg cctgtctaag tgcttgacta atttagcacc
    29221 aactggatca gaaatagctg acatcacaac cgggatagtc ttggttgctg ctgctaatcc
    29281 ttgagctgca ggcgttgcga tgccaacaac aatatcgttt gttttgacca gctgcttgct
    29341 catggtctga atcttacttt gatctccttc tgcattcata agggtaatgc tgaccttttg
    29401 ctctggctga tgatgcttct ttagctcgtc tttaatgccc tgtgcaatct ggtcaagcgc
    29461 ctcatgagta accagctgca atataccaac cttaaccaca cgcttgctgg ctaactgtgg
    29521 ctgttttttg ccctctttta gcactagcga agcagcaacc attaaaaaga gtgcaatgac
    29581 tgttacgata agacctttat gtttcatgtt ctacctctta atttccattc ttactccgtt
    29641 gctaacattt agagtactca caaaaagaaa aaacgcttag taatcagcta ctaggcgctt
    29701 tttttgaaat ccaatgtcag cgcatagata cctttttaga agtactctaa aagtcgtatc
    29761 tatgctaacc cataaacaca actttatcta tgccagcttt gccaatttat catatgctgt
    29821 gtttgcttca tcttggattt cctttcttgt ttttttacat tataacctaa aagctcaaaa
    29881 atacaagagc atttgaacat atttttccat tattttttgt ggtataatga aagaattaga
    29941 actcaggagg gagaaaccat gtcatttgac ggctttttct tacatcattt aactcaagag
    30001 ctcaaccata gtattgttaa tgggcgcatt caaaaagtca atcaaccctt tgataatgag
    30061 ttggttctga ctatccgtaa ccatcgccaa acttacaagc tcttgctctc agctcatccg
    30121 gtttttggac gcattcaact gacccaaaca gactttcaaa atcctcaatt tcccaatacc
    30181 tttaccatga tcatgcgcaa ataccttcaa ggagctatca ttgaaggctt tgagcagatt
    30241 gataatgacc gcatcatcga aatgaccgtc tctaacaaaa atgagattgg cgatgccata
    30301 aagacgacat tgatcatcga aattatgggc aagcacagca atattattct ggttgaccgt
    30361 catgaaaaca aaattatcga gtctatcaag cacgtcggct tttcccaaaa ttcctaccgg
    30421 actattttac caggatcagc ctatatcgag cctccgaaaa caactgctgt caatcctttt
    30481 acgatctcag atatcgcttt atttgaagtc ctgcaaacac aggagttatc tgctaaaaat
    30541 cttcaaaagc atttccaagg gcttggccga gataccgcac aagagctatc cagtctcctg
    30601 acaactgata agctaaaacg gtttagagac ttttttcaaa gacctagtca gccaagtcta
    30661 actcagacct cctttgctcc agttgccttc tcaaacacac tgaagacctt ccagaatcta
    30721 tctcagctgc tagattatta ttatcatgac aaggctgaga gagatcgtat caaccagcag
    30781 gccagtgacc tgatccaccg cgttcaaaac gaattggaaa aaaatcgcag caaactgatt
    30841 aagcaagagg ctgagctgct agccactgaa aatgcggagg actttcgcca aaagggtgag
    30901 ctcttaacaa cctatctgag cctggtgcca aatgaccagg attcagttga gcttgataac
    30961 tactataccg gccaaaaaat aaccattgca cttgataagg cgttgactcc caatcaaaat
    31021 gcccaacgct attttaaaaa atatcaaaaa ttaaaagaag ctgtcaagca cctctcaggt
    31081 ctcatcgctg acacgcaaca aaccatcgct tattttgaaa gcgttgatta caatctatct
    31141 caggcaacga ttgatgaaat tgaggacatt cgagaagagc ttattcaggc tggctttgtg
    31201 aaaagccgta agcataacaa gcaccacaaa cgtaaaaagc cagagcaata cctggcttca
    31261 gatggcaaaa caattattat ggtcggacgt aacaatctgc aaaatgagga attaaccttt
    31321 aaaatggcca aaaaaggcga gctctggttt catgctaagg atattcccgg cagccatgtg
    31381 atcattaagg acaatctaag cccaagcgac gaggtcaaaa ctgatgctgc tgaattggcg
    31441 gcctattatt ctaaagcaag actttccaat ctcgttcagg tggacatgat tgaagccaaa
    31501 aagctgcaca agccaagtgg tgcaaagcct ggctttgtca cctatacagg acaaaagaca
    31561 ctaagagtga cacctataga aagcaagatt caagccatga agtgctcccc ttcagcctct
    31621 tcctcatagg actacagcaa taaagataaa aaaagctaca gcctcacact tggagatagg
    31681 tccagtctta aagctgcggc ttttttatca ttacttgtta atcatctctc aaatcatcta
    31741 agaagccttg catatgaata tcatctggaa cctgctgcaa ataccttttt gcctgcttaa
    31801 ctgcttgatc agtatagccg aattccctta ataaataagc ataatcctgt aaaaagtcag
    31861 gattttcttt taggtctcct tcgatatctt tatagatagt gagggctttt tcttgctgct
    31921 ccagagcctg ataggccttg gcaagattcc atttagttag cacatgatca atctcctcat
    31981 gctcaagagc aatgacctcc tcaaaacgct ccatatccaa gtacaggcta gataagcgca
    32041 tgatgacctc ttcgtcatca acagctactt ccttggccct gagcaaatac cgctctgagc
    32101 cagctggatc atgcaattca aaggcaagct gtgaagcaag caacagcagc tgggggtcaa
    32161 aggcattttt acgcagaccc tgctgaacta ggcgtaaggc ctcttctgtc cgatgctcct
    32221 cacgcaagct catggcatag gggtactcgt agcctaaaaa gtctgcattc atcgtttcta
    32281 attgcttgaa atagagattg gccttttggt aagcagcctg atcatataaa atcgtcgcca
    32341 gctcaaacac tgtctcatcg tcatactcaa tggcaagagc cttttcaaga aactctacag
    32401 cagcttcaaa tttccctaaa taagcatagg cacgccctat gcgctggtag gttgagatac
    32461 ctgtcagctc aagaatgtga cgattatcaa gcctagcata ttgctcaata gcctcgctaa
    32521 agtgctccag agacatctcg atttcggcta agccaaagat cactatcggc tcctgactca
    32581 attcagctgc ttgaagtagc ttctcacgcg ccacatcagt tagcccctcc aaatcataaa
    32641 gatcagccat gacgagcaga gcagacaaat aatcagcact atcctctgga atcctatcaa
    32701 ggtacataaa ggcctcttca atgacattat cctcagctgc aatctgagca agattaatat
    32761 tgacctccgg ataagcctca cagacctgca aataaatcgt cttagcatgc agtaaaaaac
    32821 caatactctc taggtattct gccaaagcca acaaggtctc agcatcgtcc tcctgcaagg
    32881 ctctttgaaa atagctttct gcctgctcta aatcctgttg ctctagtgag gcaatcattt
    32941 tttcactatt taacatcttc agcgaccctc tcagcttctg taggctcttc ctcatacagg
    33001 cctgtaatat ccttgtacca atcaaatagc tccttcacaa caaccttaac agaagcataa
    33061 actggaatga caagaaagac accccagacc ccaaacattg accctgctgt caataataaa
    33121 aacataatgg taatcgggtg aatgctcagc ttatttccaa gcactagcgg cgcgacaaaa
    33181 cgtccttcaa tcgtttgttc aataacaaaa ataatcaaca ccttgatcag catcaagggt
    33241 ccttgcacca ttcccataat cactacagga atcatggcta aaaagctccc cagataagga
    33301 atcatattaa gaaagcctgc aataatacca aaggtaatag aatagttcaa accaacaagg
    33361 ctaaacatca ctgaaaacat gagaccaacc acaatcgcaa cggtcacctg tccctgcaca
    33421 tagccagata attgcttgtt gatttctcct aagacacgtg ccataggctg gcgcagctta
    33481 atcggaagca cattgaccaa accatttttc atatggccac tgtcacgcag aaaataaaag
    33541 agaataaaag gtgacatgat gattgcaaca gtaatacggg caatagctcc agcaaaattt
    33601 cctgcccaat caatagcatt tttagagaag ctttgcgcat aatctagagc cttttggctc
    33661 atactagtca gcatatcctg caggttggac ctgtagctaa ccagccattc gttttcaagt
    33721 agcttattag cctctagatt gaccttggca acatatttgg gaaggtcttc gacaaagctc
    33781 cttagctggt cttgaatcat agggataaag ccagaaatag cccagaaaaa taggagaatt
    33841 actaagccaa agacaataaa aatagaggct gtgcgatttg gacctagctt ctcaaccata
    33901 tcaactaatg gcttggtcaa ataatacagg atagttgaga taaccagcgg cagcatgata
    33961 atggccaaaa atgacaagat cggtgtaaag aggaaggata tttttgtaaa gacaaaaata
    34021 gtcagaaaaa ccagcagcgt gattaacaaa accatcaccg cctgattatt taaaaaccat
    34081 ttgtaaaata gactatcatg atgattaggc ttagaatgca atgacattaa tggtatcgtc
    34141 ctttcttaat tgtggcatca ttctgatgag agcttttagg ttagttgact taataaaagg
    34201 tgactgtttt ttccactagc ttgttgtggt catcatacct aaatttagca gaaaaaaacg
    34261 gccggtcttc cagtatccac ttgaaaatgt cgtaatctcc ctcccaggtt ggcttttcca
    34321 gcacctgatc atagggaacc cattctaggg tcccttctct ggactcctca tcagcaatta
    34381 agtcaccttc aaagtctgtc accttaaaca cgtaagtata ccaatcatgc cctggtgtaa
    34441 aatcaggaaa ggtaatcact cccttaaagt ccattgcttt taccagcagg tgagtttcct
    34501 ctaaaatttc acgtctggca cagtcatcag gagattcgcc tggctctaat ttgccaccaa
    34561 ctgaaatcca cttaccttgg tgaacatcat tttccttctt gttgcgatgc agcagcaata
    34621 aagcctcacc gttatcaata taacaaatcg ttgctaactt agtcattcat acccttcctt
    34681 tgtttagttg ttactattat accaatctct gagaaatatg ccatcatttt atcatttaag
    34741 cacatcaaac aagaaaacca caatcactac aactcttagc cctgtactag caaaaaagcc
    34801 ttgataaggc aacgtctgct gactcatcaa gacttatcac tatttaacga atcacttcct
    34861 gtgtcttagc gtaattggct tcaactgctt ctttttcgga acgccaccaa tcctgatgat
    34921 cagtatacca ttggatcgtt tgctcaagtc cttctgaaaa atcagtaaac tgtggctccc
    34981 agccaagctc ctgacgaagc tttgtcgaat caatagcata gcgtaaatcg tggcctgcac
    35041 gatccgttac atggtcataa gcgtccttag gctgccccat tttatccagg attaattcca
    35101 gcacttcctt attatttttt tcgccgtcag ctccaataag gtaggtctca ccaatacgtc
    35161 ccttggtcaa aatggcccaa acaccagttg agtggtcatt ggtgtgaatc cagtcacgaa
    35221 cattctttcc ttcaccatac aattttggct tgataccaga caagatatta gtgatctgac
    35281 gagggataaa tttctcgata tgctggtagg gaccataatt atttgaacag tttgaaatgg
    35341 ttgccttcac gccaaaggag cgaacccagg ccttaacaat caaatcagag gctgccttgg
    35401 ttgatgaata aggtgacgac ggattatagt tagtatcagc ggtgaatttt tcacctggcc
    35461 cctcaccatg acctggcaaa tcctcacgca gtggcagatc cccataaacc tcatcagtgg
    35521 acacatgatg gaagcgaata tcatatttac gagccgcctc taagagtgta taagtcccaa
    35581 cgaagttcgt gtaaataaat ggacttgggt cattgagtga attatcattg tggctttcag
    35641 cagcatagtg gacaatagca tctgccttag cggccagctt atctaccaat tcagcatcag
    35701 caatgtcacc aacaaccaac tccacgcgat cacccaaaat ctcctcaagg ttggcacgat
    35761 tgccagcgta ggtgagctta tccaaaacag ttacgtgaac ctctgggtga tggttgtaaa
    35821 cataatgtac gaagtttgaa ccgataaagc cagcgccacc ggtaacaata atgtttttat
    35881 attcagacat gttttttctt ttcctttgtt ttcagctatc agcactcaaa atgcagctta
    35941 atccgacagg caagctcagt taccagtgaa aacagcgact aagctgcctc acctcattgc
    36001 tcctaccatc cataaggtcc ttcctatcag aaggatacag agacactccc atcaaaagcc
    36061 atagcttatt tcaaatgcta attatgataa atcttcttgt ctcaaaggct taacggcctc
    36121 taggaaggga tggcttttat ctgcttctga aacctctgct tgttcaagac tttcccacgc
    36181 aatcccaagg cttgggtcag cataattaac aaaggcatat ttttgcttga gctcaagcgc
    36241 ccaataatca ttgaccagat aggtataagc caccttatca gtcagtactt gaaagccatt
    36301 agcaacacct cgagggacaa aaatcccctt tgaagcgtca atgactgttt gataggtatg
    36361 cccaaagcta tcaccctcac gaagatcaac ccaagctcca agaaccttac cctcatcagc
    36421 aacagagatg tacttgtccc aaggctctgc atgcaggcct cgaagcacat gcttgcgcga
    36481 aaatgaaata ttgttttgca gcttacctgc ggcaaaaaac tgctcaggaa agcctagagg
    36541 aatcattttt tccttttgaa aattttcctt aaaccagcca cgattgtccc ctcgaacagg
    36601 gatatcaaac tccaaaagtc caggaatggc ttcaatttcc cgacaggcta aggctttatc
    36661 aaaaaattgt tctgtcatca agcttctcca atcaaccgca gcaggtactg cccgtattcg
    36721 tttttcttaa gcgactgcgc tagctggtag acatcttctt tagtgatata acccatgcga
    36781 taggcaatct cctctaggtt ggccacctga gcgttttgca agcgttgaac tgtctcgatg
    36841 tattgggcag cctccagcag gctttcatga gtgccagtat ctagccaggc aaagccacgt
    36901 cccatcaact caaccgatag gtcgccacgc tctaaatagg ctttattaac atcagtaatc
    36961 tcaagctctc ctctggcact tggtttaatg cttttagcaa tctcgactac atcattgtcg
    37021 taaaaataaa ggcctgttac agcaaaatgt gacttaggaa ctgccggctt ttcttcgata
    37081 gaaatggcat tcatctcatc gtcaaactcc acaaccccaa aacgctccgg atccttgacc
    37141 tgataaccaa aaacagtggc tcctttttcc ttagctgctg ccttttggag cattttcgta
    37201 aggccgtttc catgatagat gttgtcacct aaaatcaagg caactcgatc atcaccaata
    37261 aactcctcac caatgataaa ggcctgtgct aagccgtcag gacttggttg ctccttgtag
    37321 gacaagctta tcccaaactc tgagccatcg cctaatagct cttcaaatct tggaagatct
    37381 tggggagttg aaataatcaa aatgtctcga atccctgcca gcatcagtgt tgataaggga
    37441 taataaatca ttggcttatc ataaattggc atcaattgct ttgaagctgc acgagtaaga
    37501 gggtacaagc gtgttcctga tcctcctgcc agaataatac ctttcatcgt agctctcctc
    37561 attttataat acgtcactat tttatcattt tttaaaaaca gtgtcacttt ttatcattaa
    37621 tccgacgaat ataatgatga atcgggtatt gactagtatc taagctagct ttttgcccca
    37681 aaagcagggc aatcagctgc tgagcaatca aaggacctag ggtcaagcca gatgagccta
    37741 gaccgcttgc ggcgtaaaca cctggtagct gaggtacctg cccaaaaaat ggagaaaaat
    37801 ctctggtata ggctcgaatg cctacgcggt aagaaacatc agaggcagaa ctcagcttag
    37861 ggtaataggt caaggcctcc tgctccaagg cctctaaaac agctacatca ggctcaaggt
    37921 catagccctt atcattttca tgactcgctc ctacagacaa cctatcatgc tcaaagggaa
    37981 taatatccag ctccccctct ggcatgacca ctgcgtagtt atctgtagtc acattcgcaa
    38041 tgtgataatc aatgagctgt cctttttgcg gtcgaatatc cacctgatag ccaagtggct
    38101 caagcaattc tggcagccaa gcaccagcgg ctagaatcag ccgatcaaag accataccat
    38161 caacgagata gccttgcttt tctatgctta tgccaacacg ctttttaacc acctgatagc
    38221 cactagcttc aagcaaacac tgacataggt ctgccccatc aacacgtgca gccccagaag
    38281 cccataccag ctgctcaaaa ccctgtaaat caggaaaatc aaccctaatg tccgaacgac
    38341 accttatcgc caaatctcca atcaaaggcg actcttgctt gcgtctaatg gccagctggt
    38401 agagctcctc tagcttgtcc tcattctttt ttaataaata aacaccagtc tgcttataaa
    38461 aatgtgtaga aagcccctct ttttgcagct ccttgattaa gtcctgataa caatctgctc
    38521 ctaaccgagc cagctggtac caagccttat tccttctttt tgaaaaccaa gggcagataa
    38581 tgccagcggc tgccttagtt gcttgaccat taccatcatc aaaaatagta acctgctgat
    38641 acccttgttt ttttaaataa taagcggcgc ttgaacctac aattccagct ccaatgattg
    38701 ctatcgttgt cattgccgtt tccattctat catactgctt accaagcata ggccatactc
    38761 agtcatgcta tagatgacta aagggatttg ttgacgcctt gctagccata atggttactt
    38821 gccagccttc ctcttttttc caagcctgca tcttggcaag tagtttatca ataaataagg
    38881 actcgatgtg atgccctgga tcaattgcca gcaggccttc tgtcagcatt tcctgtgctg
    38941 tgtgataata aatgtcacca gtaatataaa cttgagctcc cttagcaagc gctgcctgat
    39001 aaaatttatc accactgccc ccacaaatag ccactcgcga aatcaaaggg ttttgaccag
    39061 tatatcgaac cagccgaacc acatcaagcc caaaggcttc tttaactgta agtcctaact
    39121 cctccaagct ttgctctgct acatttccga cacgtccaat accataccca tcttgcgtct
    39181 caaccaatac ctctgtctgc tcaatgccca acagctcaca aaaccaatcg ttgagcccgt
    39241 cagagacaat atctatattg gtatgactga catagacaga aatatcgtgc ttcaccagct
    39301 caaggacaat atctcgctgt ggcgaggaga ccaagtcctt caagccctta aaaataggag
    39361 cgtgcttggt gataatcagg tctaccttgg ccgcaatagc ttcggcaacg gtattttctc
    39421 tcacatcaag ggtgatcatt acccttttga cctccttatc cagagagcca atttggaggc
    39481 cacacacatc tcctgacatg gatagctcaa gcggacaata gctttcatat ttttcgatga
    39541 ttgttctagc tttcatgact gatgacctcc tcaatcgctt ttattttttg agaaatgcta
    39601 gcgcgttcaa caggcttcgt tgctggcaca caagacaggg catagacaag cttatctcgc
    39661 tctttttgcc atttagccac aaagactgat gacctttcct gagacaagaa aggaccaaag
    39721 cgctgctcct gatctgttag actttgttga ccaggctctg caacaatgat ttcataatat
    39781 ttgccatttt ctgtcatgat ggtttcagca ctaatacaaa aagcattggc agatagccaa
    39841 gcacgcagct catcctctcg attattgggc tgtaaaatca agcgctcaat cccttgcagc
    39901 ttttccttac cagccgctaa aatgtcagct attaaacgcc ctcccatgcc acagatggtt
    39961 atgcagtcta cagcatctct cgcctcaaag gcagctaagc cattagccag acgcacctca
    40021 atatgctctg tcaaaccata ttgtgacaca ttttttaggg ctgatacaaa aggtcccttg
    40081 accacctcac ctgcaatcgc ctcttgaata tgctcggttt caaccaaaaa aataggaaga
    40141 taagcatgat cacttcccac gtctaaaagc ttagcaccat cagggacata ggatgccaca
    40201 tggcgtaagc gctttgataa atgactttcc attttcttaa tccttctaac aactaatcgt
    40261 atcactatta tagcaaaata cagaccaatt aaaaagaaag ccacatcaga ccttcttttt
    40321 accataggta gtcttgtaat agctgcaata gctctgtact gggcaggtat cacacttagg
    40381 atgcttagcc aagcagtgat agcgtccaaa aaagatcaaa cggtggtggg tgatgatcca
    40441 atccttctta ggaagcttgg ccatcaaatc agcttcaatt tcagtaacat cggcatctgg
    40501 ggcagaaatg ttcaagcgct tggcaatcct tgacacatgc gtgtcaactg cgattgcagg
    40561 gacaccataa atctctgcca agaccacatt agcagtctta cggcctactc ctggtaagga
    40621 ttcgagctcc ttatgggttt ttggtacctg accatcaaac tgtgtcagta gctgctgagc
    40681 tgtcttgatg atattttttg ccttattttt atacaagcca attgtcctta ggtgatcctc
    40741 aacatctgac acatttgcct gagccaaatc tgaaagctct gggtagcttt gccacagctt
    40801 aggggtaacc ttgttgactg ccttatcagt tgtctgcgct gataggataa ccgtaataag
    40861 aagctgaaag ggcttttctt ggtcccaatt cagctcgccc ttagcctctg gaaacatctc
    40921 accaatgatt gatagaacct tttttaatcg ttctcttcct atcctcatta gttactccaa
    40981 aggttcatcg ccgcaagaaa atcatctgaa accgtcactt cagacgccgt catatcctct
    41041 ctggcacgct ttttttcctc aagctgcctg aggcttgtaa ttccctcctt gcgccaattt
    41101 cttagaatag cctgaatata tttccaattg gtttttccat taaagacagc ctctctcagc
    41161 gcctcacgca ctaaatccag atctgtttgg tcatcatgaa tggttttttc caaatcctct
    41221 agctccatcg gactcaaaaa acgacccagc tcacgctcaa actcatcaac aagaagtttc
    41281 aattggttgg tgttttgctg ttcatgctca cccttttcat cacgcgccaa tagctggtct
    41341 aaagtgacta atacaggact agcatcaaaa atgatctcaa tctctccagc cagctctatg
    41401 gttttcatat ctaataaccc ctgactggtc aaggaagaaa tagccttatt cacctctgct
    41461 acagacttac ccaaggcatt agcaatctga ctaggtgcca attcgtcaag cctagtcgta
    41521 ttttggagat agaaaaactg ccaaaccaaa aaatcgtctg agctcttaaa aatatccttg
    41581 taatgaaaca gtaaggcagt tggaaggacc aaattgccag actgataatg ctctaaaaaa
    41641 ctcataattc ccctgccaaa cgtaatagcc caacctagct tttaatcagt actgccatta
    41701 gcaagcactg attaaccagg aaaatgcatc aataccttac aatcgtaatc accaatagcc
    41761 tgacgaccat tcaagccgtc cagctcaatg agaaaagcgc agccagcaac aatgccgccc
    41821 agcttttcaa ccagatcaat agtagccttt actgtaccac ctgttgctaa taagtcgtcc
    41881 acaataagga cacgttggcc cggcttaata gcatcagcat gcatggtcaa ggtgtctaga
    41941 ccatactcct tttcatagct agcagaaatc acctctcttg gcaatttacc cggcttacga
    42001 acaggagcaa agccaattcc tagctcaact gcgaccggac agccaataat aaagccacga
    42061 gcctccggtc caacaatcat gtcaatgtcc ttatcgcagg catattgcac aatctcacga
    42121 atagcatagc tgtaggcctt gccactagcc attagcggcg aaatatcacg aaaggtaatc
    42181 ccctcctttg ggtaattctc aattgaagca atatattgtg ttaaatccat cgtaaaatag
    42241 tctttctaat gtcttttaaa ttaaaatctt tcctattata gcatgaaagt ctaaaaaggt
    42301 aaatgattcc taatcatcca gatcaatccc tttttccttt aaattagtca ggcattcctg
    42361 taaataggcc tcttgatgct caggataaat cggtgaggtc agtgccacct cctctaagtc
    42421 ctcataggcg gcaaggcttt ttcctcggta atttttatcc tgccagctca catctggctg
    42481 gtagccccgc gcctgcattt cctgcataat caacaggtga tactggtaaa gcttataaag
    42541 agaatgggca aacacatagt caaccgtcgc atgtggtctc ccccagcctg ctcctcgcaa
    42601 ggccgcacat tcacgatgct gccccaacaa ttgctgcctt ggtaggcgtg tgattaaatc
    42661 ctgatgccaa agacgcataa gctctcctat ttctcttcac tagtcattaa atactgataa
    42721 atctcctgcg gactgcccaa ggccataagc tcttgaaact ttaccagctc ttttagctgt
    42781 tggtaaatga cactgtcagc gatgctacgt tttggggcat cagtctttac cctcatcagc
    42841 ccatcttcga ttactacaaa gcctaactcc tcaaaaattt gtatcatttt gaccaagagg
    42901 attttttcaa tcttgaggta atcacttagc aaggtcagct tatggcgaag atcaaattct
    42961 gggtattgat agatggtctt ataaagcttg gcaaattgct ctctactgcc atagcctgtt
    43021 aggtaataag ggcgcttaat atgattttta aagtaaatcg cttcaaattc ccgatgtcta
    43081 aaaaggcctt tcaaggcatc aatatcgtca ggaacctcat ctatgacaac aaccttggcc
    43141 tgctggtcct caacagctgt aggaatatgc tcaggtgccc tagcagtcct tgctcgaata
    43201 tcaaacagct gcaccccagt cactctagcg tcaaccagca ttaattgcag gctagtatga
    43261 cctcgccagt gattgatcgc aagactaacc gctaattcca agccctgtga ttgctggtac
    43321 tcctgtatca gatgtccctg accaaaggcc aagacatcag cctcaacggc tcctttgctg
    43381 accttgaact tcaagtgact ttgttgctga ccaatggtcc ttgcctgctt aatcgtaaaa
    43441 tcttttaagt aaaaaacagg ctttttatta tccatgccaa agggtgctag aagtagcagc
    43501 ttgttcagac tatctatact caatgcttct aaatccaatt caccattgat caatagagtg
    43561 tttttttcct gaccatcgtg tcccttggct gccacgtatt ggcaaagtag ctctgatagc
    43621 tcctctaggc gatcagatgg cagagtcatg cctgctgccc cctcatgacc accaaaggct
    43681 gtaaataagc tcctattgct attaagtgct tcaaagatat taatgctctc taagcttctg
    43741 gctgagccct tggctagccc ctcatcaatg gtcaaaacaa gaacagtctg cccaatctcc
    43801 tccatgatcc gaccagctac aatccctaag acccctgggt gccagccaga cttagctaaa
    43861 acctgcacag gcttgtctag atcaagcata gccattgctt gagcaaaaat ctcctgtacc
    43921 aagacctttc tttcctcatt tttactacta atcatcaagg caagctcatg aagctcttcg
    43981 tcatcaaagc ctgtcagtag atcaatagct ggatttggat cgtcaagacg ccctagagca
    44041 ttgagctgcg gagcaagctt aaagctaata acatcttcat caaaatgcgc taagtcaacc
    44101 tctgaaagct tcatcagctc ctgcaagcct agtctttctg tctcttttag aacagccagc
    44161 ccgtttttga caaggatacg gttttcacct cgtaggctga ccatatcagc aattgtccca
    44221 atagcaacca gatctaaaaa gtctactgga attgtctcta acagagctga agccaacttg
    44281 aaggcgacgc cacagccagc tagtttttga aagggataag cagcagctgg gtgctcaggg
    44341 tgaataatag caaaggcatc aggtagctct gctggcaggc tgtggtggtc tgttacaata
    44401 acatctaccc cctgtgcttg cgcaaaggca accgcttcat ggcctgaaac accattgtca
    44461 acggtaataa tcagcgaaac ctgctcttgc tcgatgaaat acttgtaaac actttgattg
    44521 ggaccatagc catctgtaaa gcgattaggc aaataaacaa gaggctctgc tcccatcatt
    44581 tccagcgttt ccttgacaat agacgccgct gtcatgccat ctgcatcata atctccgtag
    44641 accaaaatcc tctcaagccc ctcaatggcc tgacgaatgc gatgaacagc tttttccata
    44701 tcatttagca aataagggtc atggagctgt gataggtcag ctgtcaaaaa gctggtaagc
    44761 tcctcttcgg tatgaacacc tcggtcatag atgagctttg cagctgtctg actaagtccc
    44821 tttgcctgag ctagcttaaa gaagccagca tctggctcct tatcagctat ggtccactga
    44881 tatttggacg taatcattta taattaaata cctttcttgc aagataatca gatatagttg
    44941 gaaacaaggt ataacactta tgagcaaggg ctaggctaat aggcagatta atctctcgtt
    45001 tcttttttcc tattgcagca atgatttttt tcgccacagt atccgcctgc agcgtaaagc
    45061 ctgcaacact ggctaaatac tgcccgcttg ggtcagcctg ctcaaaaaag gaggttgcaa
    45121 tcgggcctgg attaacagtt gtcacataaa cctgcctttc tgccagctcc aagcgaaggg
    45181 cattagaaaa gccaatgact gcaaactttg tcgcagaata gatacttgac ttggcagaag
    45241 ctattaagcc tgccattgag acaatattca taatatgtcc agagccctgc tctgccattt
    45301 tgtggccaag caagcgtgca aaatgaatgc tggctaagct attcacacga aacatggcct
    45361 caatctcttc tgcagagaaa tcatcaaagg ccttaaaagc accaaagcct gcattgttaa
    45421 tcaaaacatc aatcctgcca tggcgctggt aaagctcatc aacaagagcc tcaatagcag
    45481 cagggtcttg aatagcaatc tcgtagcatt ccttattacc gcgagcctga tatagactgt
    45541 ctaacctgtc tttgctgcgc cctaacaaaa tcaggtaatc ttctcttgga agctgtctga
    45601 tgatagcctg tgcgagcccg ccagaagcac ctgttatcag aataattctc tgtgccatta
    45661 aatgatcact tcctctaaat cgcgaacaac cttcacattt tcaaaaatag ttgccgcatc
    45721 cttttccatt tgacgacagt cacgtcctaa aaagcgtgct gaaacatgat tcagtaaaag
    45781 acgcttagca cctgcatcac gcgcgatttg agcagcctgc atgtttgtcg aatgcccatg
    45841 attacgggcc attctttcat cacccttccc gtaggtggac tcatgcacca gcacatcagc
    45901 atcttttgcc aatctaacac tagcagatgt cttgcgtgta tcgccaataa tggtgatgat
    45961 ctttcctttt cgaggctctg aaataaagtc cttggcaaaa attttggtgc catcctctag
    46021 ctcaatatcc tgcccatttt taaccttgcc aaaaagtgga ccaaagggca ctcctactgc
    46081 tctaagagct tctgcatcaa gtgttccttc taaatccttt tgaaccacac gataccccat
    46141 acaaaagatg gtatgtgcca agcgctcagc ataaacaata aatttatctg tttctaaaat
    46201 cttgcccata gaggtgtcat caaactcatg ataatgaatc tgataaggca atttagagcc
    46261 tgatatcctg atgctgtttg ttacatagga ttttatccca acaggtccat aaatctcaag
    46321 gtccgtctgc tcctcactag cttgaaaagc ccgactagat aaaaagccag gcaagccaaa
    46381 aatatgatca ccatgcagat gcgtgataaa aatcttcttg atttttcgtg gcttgattgt
    46441 tgtttctaaa atttgccgct gggttccctc gccacaatca aacatccaca cctcattgat
    46501 ttcatctaat agctttagca ctaagcttga aacgttgcga tgcttggctg gctgcccagc
    46561 tccagtacct aaaaattgta attccataca gtctattctt tctaatgcac aaggtaaatc
    46621 atgaattctc tttgtgcaaa ctgataatat ttctttcctt tgaatgcttg gctaagagcc
    46681 aacaattcat cactattaaa gccctttagc agggtcattt cgtttgagaa acgatagatc
    46741 gtggttaaca aagcatgctc aggtgttatg tcctctggct ctccttgctc aaattggcag
    46801 ctcttcatct tgattctacc atcttccaca taaaccacgt attgtggaaa aatctgagcc
    46861 agctccagca gcagcgattc ctcaggctgc ccctgctctt tttcagcaaa aacaatcgcc
    46921 tcctgtgctt cattttcaaa gacaaagcca taggattgcc ccaacaaatt taagcggaca
    46981 aagggcttca cctcatcaaa tgacggctct gaggtaaaca gcttcaaggc ccttgatagc
    47041 tcaaaataat aatctgtcgc tgcttttggt gattgcttct gatacatttc tgcaaaataa
    47101 gcattaatca cacttggggg tggcgtgatg gtagctaatt tttgctggtc tgtcaagccc
    47161 tttaagcaat tttgcaaata aaccgtatct aaactcgtaa agcctccata agtctttgcc
    47221 aattgaatat aatcagtcat aaaattcttc taatctccat ttatttttgg gagcaatgta
    47281 gccagaaatc tcttcaatct ccttatcaaa gctataaggc tccaataacg ccaacctgtt
    47341 gaggtcatag catttgtagg cttgatcctg acagagcttg atcgaaaatg gctcaaacat
    47401 gtcccgaatc tgatcaataa gcaactgtct taagaggcta cgactgtttt tatcacgtgc
    47461 tgacagcctg acatttggaa aaacagttgc agtcaagcta gctgtcttat ccatcttgtt
    47521 ataaatagcc agccttggaa tatccagcat atctaaatct ttcaagatgt ctagaacaac
    47581 cctctcatgc tccaaatgat tagggtcact ggcatcaatc acatgcaaga gcaaatcaac
    47641 atgccgactt tcctctaatg tcgacttaaa agcagccacg agctccgttg gtaaatcttg
    47701 gataaagcct acagtatctg tcagagttgc ctgaaactga ttttgcagat aaatttgctt
    47761 ggtggtggca tcaagtgttg caaataattc atcagcctca tattgcttgt caccagtcaa
    47821 aatagtcata atagtagact tacctgcatt ggtatagccg atcaatccaa tattaaagac
    47881 atcagaggtc atgcggcgat cacgaatcgt ttgacggttt ttttcgacag cagctagctg
    47941 ccgctcaata tctgcaatct gatgacgaat ggagcgccgg ttcagctcca gctggctctc
    48001 acccggccca cgactcccaa tgcccccggc ctgacgacta agcataacac cctgtccgac
    48061 cagtcttggc agcatgtatt tgagctgcgc taaatgcacc tgcaatttcc cttcatggct
    48121 tctagcccgc atcgcaaaaa tatcaagaat cagctgcatg cgatcaatga ccttaatacc
    48181 taaggcgtcc tccaaattgg cattttgccg agccgttaaa cgattgttaa caatcactgt
    48241 atcaatctca ttggcagcaa ccatttcttt gatttcagcc agcttaccag agccaacaaa
    48301 ggtcttgcta tcatagcgct ccctcttttg cagatagcaa tcaacgacct ctgcacctgc
    48361 ggtcttggct agactagcca gctctgtcat tgatagctca gcatggtcag ctgcttgtag
    48421 gaccacgctt agtaaaataa ctctttcctg ccttgccttt gtctctatca tgaacgcgac
    48481 taatcctcca aattccgtag tgtttattat agcatagttt tagctatttt cagctagttt
    48541 gccatcgata gcttcctaag gctccttcaa aaagcgctcc accctatcat atattgcctg
    48601 cggataggac gactcgctaa tcgagtcaaa gcgcactgcc atacggttac gaaaccaagt
    48661 cagctgtcgt ttagcaaagc ggcgtgtttg ctgctttagt gtggctgttg cttcttctaa
    48721 actagcctga ccctgaaagt aagggaagag ctccttataa ccgatccctc gactagcctg
    48781 aacagctgga tactgctcaa aaagccacct tgcctcctcc aataggccag aagccatcat
    48841 cagatccacc cgcttattaa tccgctcata aataacctct cgctcatcag tcaagccaat
    48901 gatcaagggg ttataggggg cctcttgatt ttctaaatcc ctagcaaatt gatttagctc
    48961 aagtgagcga atggcacgcc tgcggttaac ctgatcaagg tgaatgccct tactagctaa
    49021 tagctgataa agctctgtat ctgtcagtgt ctctagctgc tgccgataag caagtagctc
    49081 cttttgatca agatctcctc ctagatgata gccctctaac aggctttgca aatacaggcc
    49141 ggtaccaccg acaataatcg gcagtttacc gcggctaaca atatcttcaa tagctcgctt
    49201 agcgtcctgc acaaaatcaa aggctgagta agactctgtc acctcacgaa tgtcaatcaa
    49261 atgatgaacc gcaagagcct gctccctggc actagcctta gctgtcccaa tatcaaggtg
    49321 acgataaacc tgctgactat ctccagatat aatttcacca ttaaaggcac cagccaaggc
    49381 aatccctaga gctgtcttgc caacagcagt cgggcctaca atcacaatta tcttttcttt
    49441 tgtcatttat tgtctttcta cttaaaaagc agctgaaaaa gtcttttact tgaattttct
    49501 aatctttttc gctaccatat attataacat aagattgaga gacagttatg gtcctcttaa
    49561 tagaaatgga gaatgattat ggctaaaaaa catggattcg caaagggtct tgctacaggt
    49621 gttcttgcta ctgctgctac cgttgcaggt gcagtatttg ctgttaaaaa gactattatt
    49681 gaccctgagg aagaaaaagc agcatttgta gaggaaaatc gtaaaaaagc agcacgtcgt
    49741 cgtgttgctc gctaatcact aatagatgaa agattcgaca ggctttatca atagcctgtc
    49801 gaatttttta tgctgtgaga ccaagctttt tgcttagaca cataaaagaa acagctcgtc
    49861 agcgccgcat actgcctact tcattgacca acaaacaggg caaactaagg ctaattttca
    49921 ctgatatgac atgtttcgac tataaagcgg ttttgtgatt gattgatcac aatatcaaat
    49981 tgctggtgat aagggtgcag ataacgagca tattgagcgc gcctattgac atgatgaact
    50041 ccggattgcg acctctaacg ctagtatctc taccaagccg cctttggagc tctgtgtcac
    50101 catctgtata aaagtaaagc gataagtcaa acaactctgg ctctaaaaag gttgtcgaca
    50161 tgccttcagc aataaggatg ggcacattcc ccttcaccaa aaaagaggga gaccaagggg
    50221 tatcaatact caaaaaatcc agtccttgct taaacatcat gatgtcacgc ctcagactgg
    50281 ccaattcgtg cctagcaggg tgacaggctg ttatactacc aagtacctcc tctccctgat
    50341 cagggtagct aatcaaaaca gcctgactaa aatcattagc gatgatatag gcatctgttt
    50401 ctaacaattg gctttgtcca tcaggcaaaa gctgctgtaa gcgcttagca aaggttgatt
    50461 taccagatgc accatgacca ctaattctaa taagcatttt ctcacgattg gctgctgcag
    50521 ttacaatagc ttgaagtagc ttctccatta tctctcctca tcaaataaca ttctaataat
    50581 aggacatcat tctacatcga aaaacaagcc ggtctcccga aacagcctga ctgacagtaa
    50641 aaaaagattg aagggcaatc caataaggaa agcttctcca atctgattaa tagtctataa
    50701 tggcttaata tgagtgccaa atgtcttggt tatattgttc aatcgtacgg tccgatgaaa
    50761 agaagccagc cttagcaata ttatgcacaa cctttgtcag ccataggtcc tgattgtcat
    50821 aatcagccag catttgttct ttgactgcaa tgtattcctc aaggtcaatc aaggtcataa
    50881 accagtcctt agagattaac tccttataga gacggtcaag acgttcctca ttaccaagct
    50941 ctaataattc tggactgata ataaagttaa ctgcttcctt gatagctggg tgggcatcat
    51001 aatagtcttt agacacataa ccacctgtgg cataaagatc aataatggta tctgaatcct
    51061 taccaaaggt gtagatatta tccataccag caagctcagc gatttccaca ttagccccgt
    51121 ccatagtacc aagcgtcaag gcaccattga gcatgaattt catattacca gtacctgaag
    51181 cttcctttga agctagagaa atttgctctg aaatatcagt tgcaggaatc aaatgctctg
    51241 ctactgtcac attgtaattt tcaacaaggt gaacattaag gtatggactt acctccggat
    51301 cgttattgat aagctctgac aagcaaagaa tcaaatgaat aatatcctgt gcaatgatat
    51361 aagccggtgc agccttacca ccaaagataa ctgttatttt acgcttcggc aggttgcctt
    51421 ttttgatctc taagtattta tgaatcacat aaagggcatt catctgctgg cgcttatatt
    51481 cgtggaagcg tttaatttgg gtatcaatga ttgaatgctc atcaagctca attcccttat
    51541 tatccttgag gtagcgcttt aaggctactt tattatggtg cttaatttca gccaatcttg
    51601 catgaacagc ttgatcctca gcaaaggcca ttaatttttc aagccttgtc gcatcagtca
    51661 agtaagcatc accgataagc tctttaatat agtccgccaa ctcttggttg gcgaattcta
    51721 gccaacgacg gaaggtaata ccattggttt tgttgttgaa tttttctgga tacagctcat
    51781 agaaggcctt caattcgcta tttttcagga tttcagtgtg aagggcagca acgccgttga
    51841 cacttgtggc aaaatgaata tccatatgtg ccatatgcac gcgacctgtt tcatcaatga
    51901 tttggacagc tggatctgat acccttgcac gaacaagagc atctaattgc tcgataatcg
    51961 ttaccagctg cggcacaacc tcattaagga agtcaagagg ccatttttcc aaggcttctg
    52021 caaggatcgt gtgattggtg taaccaacca tcttttgaac cactgaaaca gcctcatcaa
    52081 aatcaaagcc atgcttttgt gtcaatagac gaatcaattc tggaatgacc attgatggat
    52141 gggtatcatt gatctgcacg tatgcgtaat cagctaagtc atgcaggttt gagccacgct
    52201 caagcgcttc atcgatcaag agctgagcgg cattagatac catgaaatat tgctggtaaa
    52261 tgcgaaggag ctcaccattt ttatcagaat catcagggta aaggaacagg gtcaggtttt
    52321 tggcaatgtc agtcttatca aatgaaatgc catctttaat caagccataa tcaacccctt
    52381 caatatcaaa aaggttaaga tagttcttgg tgtcacgctt atagcccaaa acatcaatac
    52441 ggtctaagcg agatttcagg gtaaagtttt taaagggaac atcatatgaa atgtcagtcg
    52501 gtactagcca agagtcatcc tctatccaaa aattaggctc tgctgtttgt tcattgtgtc
    52561 taaagacctg cttgaacaag ccacaatgat aattcaagcc aaccccttca ccattaatgc
    52621 caaggcttga gatagaatca ataaagcaag aagccaaacg accaagacca ccattaccaa
    52681 gcgatggctc caattcaacg tcctctacct cagcaattga tttgcccgca gcagccagct
    52741 cctctttgat gtccttataa atacctagat taatgagatt attagaaagc aacttaccaa
    52801 tcaaaaattc tgctgagatg taataaacct tacgtttagc tgtgtttttt gcttttttgc
    52861 ttgcttcttc tttgagatag gaaagcaacg aaagatagat ttcctcgttg cttgcacttg
    52921 caagagattt tcctaatgtc atttcagtat aatctgtaaa gcgtttcatg atatcctctt
    52981 ttcaatatag tattctagtg atgattattg gctcgaccgt atagctcagt caaatggatt
    53041 aaataggcct tgtgctctgc tttaatatcg tcctcaagca tgcgccactg ccagttgcca
    53101 ccgacagtgt ttggcatatt catgcggcta tcagctgact tatccagcaa atcctgcata
    53161 cacaggatag cagtatcaca cacagtcgca aagattgttc ttagcatggc cttggtgatg
    53221 ctttcagcag ctgccttatg gatataatga ttaacaaact caacctgctc tgcgctcaag
    53281 tgctcatacc agccattcac cacctcattg tcatgcgtac cagtgtagac aatgcaattg
    53341 tgatcatagt tatgcggcaa atcaaagctt tgacttgtca catcaaacaa accaaactct
    53401 aaaatcttca tgcccggaaa gccagtagat gccagcagct gctcagcctt ttcatcaatg
    53461 tagccaaggt tttctgcgat aattggcagc tcacccaagg cctctcgaac agctttaaat
    53521 agagcaatac caggagctga ctcccaatga ccatttttag cagtcacatc accaccagga
    53581 atttcccaaa aatctgagaa gcccttgaaa tggtcaattc taagcttatc gtacagcttg
    53641 aagctctctt tgatccgatg gatccaccaa gcaaagcctg tttgctcatg gctctcccag
    53701 ttgtaaatag gattgcccca aagctgcccg tcctcactaa agccatcagc aggtacacct
    53761 gcaatgtaaa tcggcttttt atctgcatcc accttaaaga gctctggcat cgtccaaacc
    53821 tcaacgctat cagcagacac gtagattggc atatcaccaa tgatagtaat gccattttga
    53881 ttagcatagg tcttcagcgc tagccactgc tgataaaaga aatattggca gaccttatga
    53941 taggtgatgc ctttggccaa cagcttgcgg taatgaagca aggcagcctc ttcacgctta
    54001 acaattgctc tatcgtccca ttcctggagg gccttgtgat caaaatgctc tttaatagcc
    54061 ataaattcag caaaatcatt tagccagctc gcagttgctt caaattcggc gagctgtctt
    54121 aagccttcct cagttgagac aaaagcctga actgcttttt ctaataaagg gcgtctggct
    54181 tgaaagactt gagcgtaatc aacagactcc ggatttgagc caaaatcaac agcagcataa
    54241 tcagcttcct gcaaataacc gtcctttgcc agcaattcaa ggtcaataaa atgcgtattt
    54301 cctgcaatag ctgaaaaaga ttgataagga gaatctccaa agctagttgt tgttaagggc
    54361 aaaatctgcc aataggtctg cttggtttcc tttaaaaagt caacaaattc aaaggcctct
    54421 ttaccaaagc tcccaatacc gaagcgtccc ggaagcgagc tgatatgcat cagaatacca
    54481 cttgcacgtt tagtcattct ttttttctcc ttgtaaaatc ttaatgttga aattataacg
    54541 caaccgtttg cgcaagtcaa tatcttttca aaaaaaaaga gactttttcg gcatgctaga
    54601 gctgctcaag ccttgataat aatgagggaa gcagctagga caaaaacaaa aaaaggattg
    54661 gagagacagc ctaagcagct gctcttccat cctcatctca ctcctatttg gcattaatat
    54721 ccctgacact ctctcgcttt ttgaggctaa agggaaccaa aattttctga ctcagggttt
    54781 gttcattggc attgataatg tctaagagct gcctaaagga ggttcttccc aaattttcaa
    54841 cgttaatatc aaatgttgtt aagtaagggt gaatcaattt cgaatagcta gaattattaa
    54901 aggtaataat cgaaatatca tctggcacct taatgtcata aaaggacaag agctggacca
    54961 ttcgcaccga caaaacatca ccaatcacga ttaaggctgt ggccttaaag ctacgtatcg
    55021 tttcaataac cttttcgatg cttattggat cctttcgatc aaataacagc atcggtttgt
    55081 tttccaagga taatttcaag cagcccttga gatagccaat atagcgctca gaagctacct
    55141 ctgcctccat atcgtctgtg ataaacagga tctgtcggtg acccttttga tagagatgat
    55201 caactgcggt tttagccatt agctggttgt cattgtcaat ataggtgatt ttgttctcat
    55261 caccttctgg tgcgccaaca atgacaaaag gaatctggtt ggtcatcaaa tagcctctaa
    55321 caggatcttc ttgctcagaa tataatataa taaagccatc aacacgcttt tgcaggtgca
    55381 ttaacttaac ctggctcaat aaatcctcaa cagacatacc tgttgcaatg gaaacagtga
    55441 aatgatgttt cttagcttca ttggtaatgg tcgatagaat ttccataaaa aagggatcac
    55501 tcaaacgatc attagtgata atcggcggaa aaaccaggcc aatattatgt gtcaggccac
    55561 tagcaagcat ttgcgcagct acattcggaa catagccaag ctcgctcata gctcttctaa
    55621 ccttttcctt tgtcttttgg gagatagatc gattatcctt gaggacacga ctgacggtcg
    55681 aaggattaac acctgctttt aaggcaacgt cttttattgt aaccatataa acctcattta
    55741 atacctgata atgacgctat gtcaggcttt ttcacatgta ttttgctttt attatacaat
    55801 tatctcctaa aaaatcaact ctcgccctgc aagaaggcga cataaaaaac tgctgtcctc
    55861 atgatcgaaa aaatgttaaa aaaatcaact ttttttaaaa aaagactaga ctttttctgt
    55921 aaacggttgc ataatattaa gtgtaagaaa tatatcttag gaggaaatcg ctatgaaatc
    55981 atggcaaaaa gttatcgtca gtggggcaag cttgacactt gctagcgcct tattagtagg
    56041 gtgtgcatct ggttcaaagg acaaaacaga aactgcatca ggtactgatt caaaaacaat
    56101 taagctttgg gtaccaacag gagctaaaaa gtcatacaca gatgttgtcg ctaaatttga
    56161 aaaggactct ggctacaagg ttaaggtgat cgagtcagag gatccaaaag cacaagaaaa
    56221 aatcaaaaaa gatgcttcta ctgctgccga tgtcttttca cttcctcatg accagcttgg
    56281 tcagctcgta gaatctggca ttatccaaga agtcccagag gaatacacta aagagatcgc
    56341 tgatacagca actgatcaag ctatccttgg tgctcaatac aagggtaaaa cctatgcctt
    56401 cccatttggt attgagtcac aggttctctt ctacaacaaa actaagctag ctgctgatga
    56461 tgttgcttca tacgatacca tcacgtctaa ggctaccttc ggtggtacct tcaagcaggc
    56521 taatgcttat gctactggtc cattgttcat gtctgttggt aacacattat ttggtgaaag
    56581 cggtgaagac actaaaggaa ctaactgggg caatgaaaaa ggggttgctg ttcttaaatg
    56641 gatttcagac caagcctcaa acaaaggatt tgttaactta gatgccaaca acgtcatgtc
    56701 tcagtttgga gacggttcag ttgcttcatt tgaatcaggt ccttgggatt acgaggcagc
    56761 acaaaaggct atcggtaaag aaaaccttgg tgttgctgtt tatccaaagg taactatcgg
    56821 tggcgaaacc gttcaacaaa aggccttctt gggagtgaag ctctatgcgg ttaaccaagc
    56881 tcctgctaag ggagatacca agcgtatcgc agccagctac aagcttgctt catacctaac
    56941 aaatgctgaa agccaagaaa accaattcaa gacacgtaac atcgtaccag ctaacaagac
    57001 cgttcaagct tcagaggctg ttcaatcaaa cgagcttgca aaaacagtta tcacaatggg
    57061 atcttcttca gattatactg ttgttatgcc taagcttagt caaatgggta ccttctggac
    57121 tgaaagtgct gcaatcctta gcgatgcctt caatggtaaa atcaaagaag gtgactacct
    57181 tgctaagcta cagcagtttg acaaggacat tgcagcaaca aaataagcta tctcatttat
    57241 aatactatcc taaacaagta cagaggtggg ctattttaac gctatccttt ctactcatct
    57301 ctaaaggggt ggaactaagc atcattattt tttcagggct tagtccactc ctacttgttt
    57361 ttgatatgac gtaaagcttg gtgctactta aatttttaat cgcttaaaga tttaggtaac
    57421 acttagctat gtggtcgtta gcaccaaacg cttatgacca cagcatctga acaagagagt
    57481 caggtaatcc tactttcttg tatcctaaca taaaggagaa catatatgac tcaggcaggc
    57541 ttagcatctc aggttactgt aaaagaggct ttaacaaagg gaagcttcga tattaaacta
    57601 tccgctatca tcatgggctt tgccaatttt gctaataaac aattcgtcaa aggaacactc
    57661 tttttattga gtgaggtggt ctttttcatc gcctttgttt cacaaatcat tcctgctatt
    57721 ggcggcctca ttaccctagg aacacaaaca cagggcatga caaccaaaac tatcgacggt
    57781 atcagcattc aggttgctgt tgatggagac aattcgatgc taatgctgat ttttggctta
    57841 gcctctctga ttttttgttt gttatttgcc tatatttatt ggtgtaacct aaaaagcgcc
    57901 cgtcacctct acatgctaaa gcaagaaggg gcaaaaatcc caagctttaa ggaggatttt
    57961 gttagtctag caaatggtcg tttccatatg accttgatga caattccatt gattggtgtg
    58021 cttctgttta cggtacttcc tttgatctac atgatttgct tagcatttac taactttgat
    58081 cacaatcacc tcccgccaaa gtcacttttt gattgggttg gtctttccaa ttttggtaac
    58141 gtgttaagtg gtcgtatggc aggaaccttc tttcctgttt tctcatggac actgatttgg
    58201 gctgtctttg ccacagtgac taacttcttc tttggtatca ttttagcact cttgattaat
    58261 accaaaggct taaaattgaa aaaaatgtgg cggaccttct ttgtgattac catcgcagtt
    58321 cctcagttta tttcactgct gattatgcga aatctgctaa atgaccaagg tcccttaaat
    58381 gccctgctta gcaaattagg gttaatccac cattctctac cgtttttatc tgatccaatt
    58441 tgggctaaat tctctattat ttttgttaat atgtggatcg gtattccatt taccatgtta
    58501 atcgcaacag gtatcattat gaacctgcca agcgaacaaa ttgaggctgc agagattgat
    58561 ggggcaagta aattccaggt cttcaaatca atcaccttcc ctcaaatcct cattatcatg
    58621 acaccaaacc tgattcagca atttattgga aacatcaata acttcaatgt gatctatctc
    58681 ttaactggtg gtgggccaac caattcagcc tattaccaag ctggaaccac cgatctattg
    58741 gtgacttggc tctataaatt gactgttaca gcagcagatt ataatctagc ctctgttatt
    58801 ggtatcttaa tctttaccgt atcagcaatc tttagcttac tggcttacac aagaactgca
    58861 tcatacaagg aaggagcagc gaaataatga aaaacaaacg tcgatttcag cttggattag
    58921 tttacgccat tttaaccgtt ctctcaatca tttggctttt acctatcgct tgggttgttc
    58981 tgactagctt tcgtgctgaa ggcactgctt atgtcgatta ttttcttccc aagcacctca
    59041 cattagacca ttatattaag ctctttacaa atgaaacatt tccttttggg agatggtttg
    59101 tcaatacctt tgttgttgct atctttacct gtatcatctc aacctttatt acagtggcga
    59161 tggcttactc gcttagtcgg atcaaattca agtttcgcaa tcgtttctta aagcttgcac
    59221 tagtgctaaa catgtttcca ggctttatga gcatgattgc tatctactat atcctaaaag
    59281 cacttggcct tacgcaaagt cttaccgccc tagtccttgt ttattctgcc ggtgctgcac
    59341 ttggatttta cattgctaag ggcttctttg ataccattcc ttattcgctt gacgaatctg
    59401 ccatgattga tggggctact cgtatggata ttttctttaa gattacccta ccgctatcaa
    59461 agccaatcat tgtttacact gcactccttg cctttatggg accttgggtt gactttatct
    59521 ttgcccaagt gattttagga gatgcaacca gcagatatac ggtagctatc ggactctttt
    59581 caatgctgca gcctgacacc atcaatgact ggttcatggc ctttaccgct ggatctgtgt
    59641 taattgctat tccaatcaca ttgctcttta tgtttatgca aaaatactat gtagagggcg
    59701 ttacaggtgg ttctgtcaaa tagcagtaat gatcacgata acccttactc aaaaaatcct
    59761 tccc
//
LOCUS       DARYXZ010000004        55812 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYXZ010000004 DARYXZ010000000
VERSION     DARYXZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55812
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..376
                     /locus_tag="TV186_000178"
     CDS             <1..376
                     /locus_tag="TV186_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL1531616.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TV186_000179"
                     /pseudo
     CDS             692..933
                     /locus_tag="TV186_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TV186_000180"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TV186_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL1531617.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TV186_000181"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TV186_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL1531618.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TV186_000182"
     CDS             6494..6823
                     /locus_tag="TV186_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1531619.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TV186_000183"
     CDS             6827..7261
                     /locus_tag="TV186_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL1531620.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TV186_000184"
     CDS             7263..7547
                     /locus_tag="TV186_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1531621.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TV186_000185"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TV186_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TV186_000186"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TV186_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL1531622.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TV186_000187"
     CDS             10025..10675
                     /locus_tag="TV186_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL1531623.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TV186_000188"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TV186_000188"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1531624.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TV186_000189"
     CDS             12073..12813
                     /locus_tag="TV186_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1531625.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TV186_000190"
     CDS             12810..14528
                     /locus_tag="TV186_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1531626.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HPKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TV186_000191"
     CDS             14567..15655
                     /locus_tag="TV186_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL1531627.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TV186_000192"
     CDS             15670..16374
                     /locus_tag="TV186_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL1531628.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TV186_000193"
     CDS             16634..17122
                     /locus_tag="TV186_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL1531629.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TV186_000194"
     CDS             complement(17632..18105)
                     /locus_tag="TV186_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1531630.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TV186_000195"
     CDS             18246..18926
                     /locus_tag="TV186_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1531631.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
     gene            19195..20430
                     /gene="arcA"
                     /locus_tag="TV186_000196"
     CDS             19195..20430
                     /gene="arcA"
                     /locus_tag="TV186_000196"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL1531632.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            20440..20871
                     /locus_tag="TV186_000197"
     CDS             20440..20871
                     /locus_tag="TV186_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1531633.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            20886..21899
                     /gene="argF"
                     /locus_tag="TV186_000198"
     CDS             20886..21899
                     /gene="argF"
                     /locus_tag="TV186_000198"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL1531634.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            22061..23554
                     /locus_tag="TV186_000199"
     CDS             22061..23554
                     /locus_tag="TV186_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL1531635.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            23571..24902
                     /locus_tag="TV186_000200"
     CDS             23571..24902
                     /locus_tag="TV186_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL1531636.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            24920..25870
                     /gene="arcC"
                     /locus_tag="TV186_000201"
     CDS             24920..25870
                     /gene="arcC"
                     /locus_tag="TV186_000201"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL1531637.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            26090..27082
                     /locus_tag="TV186_000202"
     CDS             26090..27082
                     /locus_tag="TV186_000202"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEL1531638.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGVENPVSVHVLNIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGQRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVARYPDLTPKERENAITKEFDAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTSESENGYHGLNGDILVWNEQLGTAFELFSMGIRVDEEALKRQVDITGDQERLQF
                     DWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVRDTYDNIL"
     gene            27254..27793
                     /gene="rsmD"
                     /locus_tag="TV186_000203"
     CDS             27254..27793
                     /gene="rsmD"
                     /locus_tag="TV186_000203"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL1531639.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            27783..28283
                     /gene="coaD"
                     /locus_tag="TV186_000204"
     CDS             27783..28283
                     /gene="coaD"
                     /locus_tag="TV186_000204"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL1531640.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            28261..29298
                     /locus_tag="TV186_000205"
     CDS             28261..29298
                     /locus_tag="TV186_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL1531641.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            29860..30474
                     /locus_tag="TV186_000206"
     CDS             29860..30474
                     /locus_tag="TV186_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL1531642.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            30478..31560
                     /gene="rlmN"
                     /locus_tag="TV186_000207"
     CDS             30478..31560
                     /gene="rlmN"
                     /locus_tag="TV186_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL1531643.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            32842..33372
                     /locus_tag="TV186_000208"
     CDS             32842..33372
                     /locus_tag="TV186_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL1531644.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            33745..33978
                     /locus_tag="TV186_000209"
     CDS             33745..33978
                     /locus_tag="TV186_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL1531645.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            33953..34924
                     /locus_tag="TV186_000210"
     CDS             33953..34924
                     /locus_tag="TV186_000210"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL1531646.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            34934..35314
                     /locus_tag="TV186_000211"
     CDS             34934..35314
                     /locus_tag="TV186_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL1531647.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            35710..37551
                     /gene="typA"
                     /locus_tag="TV186_000212"
     CDS             35710..37551
                     /gene="typA"
                     /locus_tag="TV186_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL1531648.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            37633..37887
                     /locus_tag="TV186_000213"
     CDS             37633..37887
                     /locus_tag="TV186_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL1531649.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            38033..39394
                     /locus_tag="TV186_000214"
     CDS             38033..39394
                     /locus_tag="TV186_000214"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL1531650.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            39391..40473
                     /locus_tag="TV186_000215"
     CDS             39391..40473
                     /locus_tag="TV186_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL1531651.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            40474..41664
                     /locus_tag="TV186_000216"
     CDS             40474..41664
                     /locus_tag="TV186_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL1531652.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            41876..43240
                     /gene="ftsA"
                     /locus_tag="TV186_000217"
     CDS             41876..43240
                     /gene="ftsA"
                     /locus_tag="TV186_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL1531653.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            43264..44592
                     /gene="ftsZ"
                     /locus_tag="TV186_000218"
     CDS             43264..44592
                     /gene="ftsZ"
                     /locus_tag="TV186_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL1531654.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            44595..45266
                     /locus_tag="TV186_000219"
     CDS             44595..45266
                     /locus_tag="TV186_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL1531655.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            45279..45941
                     /locus_tag="TV186_000220"
     CDS             45279..45941
                     /locus_tag="TV186_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL1531656.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            45946..46203
                     /locus_tag="TV186_000221"
     CDS             45946..46203
                     /locus_tag="TV186_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL1531657.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            46200..46994
                     /locus_tag="TV186_000222"
     CDS             46200..46994
                     /locus_tag="TV186_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL1531658.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            47004..47759
                     /locus_tag="TV186_000223"
     CDS             47004..47759
                     /locus_tag="TV186_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL1531659.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            48030..50828
                     /locus_tag="TV186_000224"
     CDS             48030..50828
                     /locus_tag="TV186_000224"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL1531660.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(51306..51608)
                     /locus_tag="TV186_000225"
     CDS             complement(51306..51608)
                     /locus_tag="TV186_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL1531661.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(51670..52119)
                     /locus_tag="TV186_000226"
     CDS             complement(51670..52119)
                     /locus_tag="TV186_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1531662.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(52279..54531)
                     /locus_tag="TV186_000227"
     CDS             complement(52279..54531)
                     /locus_tag="TV186_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1531663.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            54813..55043
                     /locus_tag="TV186_000228"
     CDS             54813..55043
                     /locus_tag="TV186_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL1531664.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(55525..55626)
                     /locus_tag="TV186_000229"
                     /pseudo
     CDS             complement(55525..55626)
                     /locus_tag="TV186_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT        15886 a        10584 c        13197 g        16145 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctgagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat gcttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcacccta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gctaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaagttttt
    18961 tgactttttt caatttataa atataagatt tttcgttaaa atgtaaaaaa caaacaagaa
    19021 aacgtataca aaaacataaa cattcatttt caggcgaaaa agtgtaatcg tttacacaga
    19081 ttggctgtga gaaataccct atttttgaat gctgcttgga gtaaactagg ggtgtaagca
    19141 aaagctaaga gtcttagcag tgaattcaca aaacattaga aagaggtaat tcttatgact
    19201 gctcaaacac cgattcatgt ttactctgaa attggcaagc tgaaaaaggt tttgctccat
    19261 aggcctggca aggaaattga aaacctgatg ccagactact tggaacgtct attatttgac
    19321 gatattccat ttttggagga cgctcaaaaa gagcatgatg cttttgcaca agcattacga
    19381 gatgaaggcg tagaggtgct ataccttgaa acactagctg ctgaatcact tgtaacacca
    19441 gaaattcgtg aagccttcat tgatgaatac ctaagcgaag ctaatattcg tggaagggca
    19501 actaaaaaag ctattcgtga gctactgatg tctattgaag acaatcagga attgattgaa
    19561 aaaacaatgg caggtgtgca aaaatcagaa ttgcctgaga ttccagcagc agaaaaaggc
    19621 ttgactgact tggttgaatc aagctatcct tttgcgattg acccaatgcc aaacctttat
    19681 ttcacacgtg atccgtttgc aactattggt acaggtgttt cgcttaacca catgttctca
    19741 gaaacacgca atcgtgaaac aatctatggt aagtacattt tcacacatca cccaatctac
    19801 ggtggcggca aggtacctat ggtttatgac cgtaacgaaa ccactcgtat cgagggtgga
    19861 gatgagctgg ttctttcaaa agatgtgctt gcagtaggta tctcacagcg gacagacgca
    19921 gcatcaattg aaaagctctt ggttaacatc tttaaacaaa atcttggctt caagaaggtt
    19981 ttggcctttg aatttgctaa caatcgtaaa ttcatgcacc tagataccgt ctttacaatg
    20041 gtggattatg ataagttcac gattcaccca gaaatcgaag gagatcttcg cgtttactca
    20101 gtgacctatg aaaatgaaga gcttcgtatt gtagaagaaa ctggtgattt ggctgagctt
    20161 ttagctgcta atctgggagt tgagcgtgtt gagcttattc gctgtggtgg tgataacctt
    20221 gtggcagctg gtcgtgagca atggaacgac ggctcaaaca cgctaacaat cgcaccaggt
    20281 gtcgtggttg tttataaccg taacactatt acgaatgcca ttcttgaatc aaagggcttg
    20341 aagctcatta agattcatgg aagtgaattg gttcgcggtc gtggtggacc tcgttgcatg
    20401 tcaatgccgt ttgaacgtga agacatctag gagaggcaaa tgacaagggt tattgttgga
    20461 aatcagcctt ttcaacgggc agctagctta tatattcgct atcaggtttt tgtcttagaa
    20521 cggcagattg atcggcaaga tgaatttgat tgcttcgacg ataacgatcg cgtgtatgca
    20581 gtcttgtatg atggtgatca gcctgtatcc acagctcgct ttttacccac agctaaagat
    20641 caggctcgtc taacaagagt tgctacgctg cgtcagtatc gtggtagggg ctatggtgcg
    20701 caggtgatag aagcgcttga gcagtatgcc agagagcaag cttacgagcg attggttatt
    20761 catagcgaga ttagcgcaca gtcattttat gaaggtcttg gctatcaagc ctttggcgag
    20821 ccttatgatg aagacggtga gccttgtcaa tcagtagaaa aatatttata aaaaggagaa
    20881 tttaaatgac acaagtattt caaggacgta gcttcttagc agaaaaagac tttacacgtg
    20941 aggaatttga atacctcatt gattttgcag cacacttgaa agaccttaaa aagcgtggta
    21001 ttccacatca ctatttagaa ggtaaaaata ttgccctctt gtttgaaaaa acatcaacgc
    21061 gcacacgtgc tgcctttaca actgcggcga ttgatttagg agctcatcct gaataccttg
    21121 gcgctaacga tattcagctt ggtaaaaagg aatcaacaga ggacacagct aaggtattgg
    21181 gtcgtatgtt tgatgggatt gaattccgtg gctttagcca acgtatggtt gaagaattgg
    21241 cagaattctc aggtgttcca gtgtggaatg gcttgactga tgaatggcac ccaacccaaa
    21301 tgcttgcgga ctaccttact gtcaaggaaa actttggtaa gcttgaaggc ttgaccttgg
    21361 tttactgtgg tgatggacgc aacaacgttg ctaattcact gttagtagca ggtaccttac
    21421 taggtgtgaa tgttcatatc ttctcaccaa aagagctctt cccagcagaa gacatcgtga
    21481 agctggctga gggctatgct aaagcatcag gtgcgcatgt gttagttact gacaatgctg
    21541 atgaggctgt aaagggcgca gatgtgcttt acactgatgt gtgggtgtca atgggtgaag
    21601 aagacaagtt tgaagagcgt gtgaagctct tgaagccata tcaagtgaac atggagcttg
    21661 ttaaaaaagc cgccaacgac aaccttatct tcttacattg cttgccagcc ttccatgaca
    21721 caaatactgt ttacggaaaa gacgttgctg agaaatttgg tgtagaagaa atggaagtaa
    21781 cagatgaggt cttccgcagc aaatacgctc gtcactttga ccaagcagaa aaccgtatgc
    21841 acactattaa agcggttatg gccgcaactc ttggtaatct tttcattcca aaagtgtaag
    21901 ctgtgattgg taccttttaa tttattttag ctcatttcat taatttaaca tttaactact
    21961 aaaaaacgta ctttaactac atgacgagtc gttctggttc tcgtgtcctt gaccggaact
    22021 gggacggctt atttttatga aaaggtaaga ggtaatcact atgacagaag aaaaaaaacg
    22081 aggttttaaa attccttctt cttacactgt tttgtttatc atcattgcta ttatggcagt
    22141 attaacctgg tttattccag ctggtgctta tgagactgct aaggatggcg gtgtgatttc
    22201 agggacctac caaacggtta agtcaaaccc tcagggcttt tttgacattt taatggcacc
    22261 tgttcgaggc atgctaggtg tcaaagggac tgaaggggca attcaggttt ctttctttat
    22321 tttgatggtt ggtggctttt taagggttgt caacaagaca ggtgcgcttg atacagggat
    22381 tgcttctgtt gtgcgtaaaa ataagggtag agaaaagctg cttattgcga ttttgattcc
    22441 tttgtttgca cttggtggca caacctacgg aatgggagaa gaaacaatgg cgttttaccc
    22501 tcttcttatt ccggtaatga ttgcggttgg ctttgatagc attgttgcag tagctattat
    22561 cctgattggt tcacagattg gctgtttggc ctcaaccatc aatccctttg ctactggagt
    22621 ggcagcagat gcagccggtg ttagtatcgc agatggtatg atttggcgga ttatccaatg
    22681 ggttgtcctt gttggtatgt ctatctggtt tgtttacagt tacgctagca agattgaaaa
    22741 agacccaagc aagtccttgg ttgctgacaa agctgaagaa cataaggaat tcttccagct
    22801 gcaaaattcc ggtgaggatt tgactagtcg tcaacgaaag gttttagcca tttttacctt
    22861 gacatttgtc atcatgattc ttagcttgat tccttgggaa gattttgaca ttcaattatt
    22921 tacaaatatc aacacttggc taacaacaac acctgtttta ggtggtatta ttggtaaaac
    22981 aatgggagcc tttggtactt ggtatttccc agaaattacc atgctcttta tcatgatggg
    23041 tgttttagtg gctgttgttt atcgcatgag tgaagatgac ttcttctcag cctttctaag
    23101 tggtgcaggt gagttcctcg gtgttgcgat tatttgtgcg gtagcgcgtg gtatccaagt
    23161 gatcatgaat ggtggtatga ttacagcaac cattcttcat tggggtgaaa caggtcttgc
    23221 aggcttgtca tcacaggtct ttgttgtctt ggcctatatt ttctatttgc caatgtcctt
    23281 cttgattcca tcaacatcag gacttgccgg tgcaacaatg ggaatcatgg ctccgcttgg
    23341 acaattctca aatgttcctg ctcatttggt tatcacagcc ttccaatcag catcaggtat
    23401 cttaaacatg atttcaccaa cctctgctat tgttatggga gcgctcgcac ttggacgtat
    23461 tgatctaggt acttggtgga aatttatcgg caagtttatc gttatggtaa tgcttgttag
    23521 tgttttgttg ttagtagtag cgacattctt ttaagagata ggaggctcct atggaaacct
    23581 atatccaacc aagacaccaa gaggcttgtg tagccgcgat taaaaaaata gtatcttacc
    23641 cttctgtgct aaatgagggg gaaaatgaca caccctttgg ccaagccatt caagatgttc
    23701 ttgaagcaac cttagccctg tgccaagatc ttggttttaa tacctatatt gatcctaaag
    23761 gctattatgg ctatgctgaa ttgggcgatc aaacagaggt gcttgctatc ctttgtcact
    23821 tagatgtggt gcctgctggt gatttgaagc tgtggcataa agatcccttt acttgtattg
    23881 aaaaagatgg ctgcttgtat ggacgtggca ctcaagatga caaggggcca tcgatgatgg
    23941 cactctttgc cactaaagca cttatggacg ctggtgtggt ctttaacaaa cgcattcgct
    24001 ttatctttgg aacagacgaa gaaaccctct ggcgctgtat gaaccgttat aatgaagtag
    24061 aggaggaggc aacctttggt tttgccccag actcaagctt cccattgacc tatgctgaaa
    24121 aggggctttt acaagctaag ctagttggta agggatcgcc taaactcaat cttgaggtgg
    24181 gtcaggccta taatgtcgtt ccagctagag cctcttatca gggagacaag ttggaggcat
    24241 taaaggaaga gcttgacagg cttggctttg aatatgttgt caaagatgac gagctaaccg
    24301 tctatggact tgctcagcat gccaaggacg ctccagatgg gattaatgcc cttatcaggc
    24361 ttgcaaaggc tcttgtagtg cttgagccag agccagtcct tgactttctt gctcatgtgg
    24421 ttgatgaaga cggcagagca gtcaatattt ttggtccagt tcaggacgag ccatcaggag
    24481 ggcttagctt caacgtagct ggtcttacct taacaaaaga gatgacagag attcgtttgg
    24541 acattcggat tccggtctta gcagataaag ataccttagt agaccagtta agccaaaaag
    24601 cgcaggacta cggtctagct tacgaggaat ttgattattt ggcaccctta tatgtgccct
    24661 tggacagcga gctagtaact accctgttag aggtatatcg taaaaaaaca ggggaccaat
    24721 cgccagccca atcatcaggt ggagcaacct ttgctcgtac aatggctaat tgtgtggcct
    24781 ttggagcatt atttcctgat gctgttcaaa cagaacacca agaaaatgaa catatcgtct
    24841 tagcagatgc ctatcgtgca atggatattt acgcggaagc catctaccga ctaacacgat
    24901 aagatgagga gtatcatata tgacaaaaca aaaaattgtt gtcgcacttg gaggaaatgc
    24961 aatcctctca acagacgcgt cagctaaggc acaacaagag gccttggttt cgacatcaaa
    25021 atcactagtg aagttaatca aagaaggcca tgaggtgatt atcacgcatg gcaatggtcc
    25081 gcaggttggt aatctcttat tgcagcaggc agcagctgat tctgagaaaa atccagccat
    25141 gccattagat acctgcgttg ccatgacaga aggcagcatt ggcttttggt tagtcaacgc
    25201 cctagacaat gagctgcaag cccaaggcat cacaaaggaa gtggcagcag ttgtcaccca
    25261 ggtcattgtt gatgaaaatg accctgcctt taaaaatccg actaaaccaa ttggtccttt
    25321 cttaaccgaa gaagacgcta aaaagcaaat ggcagaatca ggtgctagct ttaaggagga
    25381 cgctggtcgt ggctggcgta aggtggtgcc atcaccaaag ccaattggta tcaaagaagc
    25441 taatgtgatt agaagcttag ttgattctgg tgttgtggtg gtcagtgctg gtggtggcgg
    25501 tgtgccagtt gttaaagacc ctgcaagtaa aacgcttacc ggtgtggaag ctgttattga
    25561 taaagacttt gctagccaaa ccctttcaga attggttgac gctgatctct ttattgtctt
    25621 gacaggtgtt gataatgtct atgttaactt taacaagcct gatcaaagaa aattggaaga
    25681 ggtaacggtt tctcaaatga aggaatacat cgctcaggac caatttgctc ccggaagcat
    25741 gctgcctaag gtggaggctg caattgcttt tgtggaaaac aaatcaaatg ccaaagctat
    25801 catcacatcg ttagaaaata ttgacaatgt tctctcagca aatgctggta cacaaattat
    25861 cgcaggctaa ttcagatgac tgcacaatga gcttaggctt ttgtgctttg ataggtttta
    25921 gctgataagc ttgaaaaatt gatttaaaag gttaaattag gttaatttag ccttttcttt
    25981 tacttttaat cggtgtataa taagcgtaat atttttttat ttttactcat gattagaatg
    26041 gtaaaaaata aaggtgactt agtcgcgaaa atgatttaaa ggaggagcta tgaaaaaaag
    26101 ctttattcat caacaagagg aaatttcctt tgttaaaaat acatttacgc agtatttgat
    26161 tgctaagctt gatgttgttg aggtgcaagg tcctatttta agtagggtcg gagacggcat
    26221 gcaggacaat ttatctgggg ttgaaaatcc ggtatctgtc catgtcttga acattcctaa
    26281 tgcaaccttt gaggtggtgc attcgctagc aaaatggaag cgtcatacct tagcacgttt
    26341 tggctttaat gaaggtgaag gtcttgtggt gaatatgaaa gcgctccgtc ctgatgaaga
    26401 ttcgctagac cagacgcatt cagtgtatgt ggaccagtgg gattgggaga aggttatccc
    26461 tgatggtcag cgcaatctag cttacctcaa agaaactgtc gaaacgattt acaaggttat
    26521 ccgcttgaca gagctagctg ttgaggcacg ctatgatatt gaagctgtct tgccaaagaa
    26581 aattaccttc attcacaccg aggagcttgt tgccagatac cctgatttga caccaaagga
    26641 gcgtgaaaat gctatcacaa aagaatttga tgcggtattt ttgattggta ttggcggtgt
    26701 attgccagat ggcaagccac atgacggtcg tgcgccagac tatgatgact ggaccagtga
    26761 gtcagaaaat ggctaccatg gcttaaatgg tgatattctc gtttggaatg agcagctagg
    26821 cacagccttt gagctattct caatgggaat tcgtgttgat gaagaggctc taaagcgtca
    26881 ggtggacatt actggagatc aggaacgcct acaatttgat tggcacaaat cgctgctaaa
    26941 tggtctgttc cccctaacca tcggtggagg aattggtcaa tcgcgtatgg ccatgttttt
    27001 gcttcgtaaa aagcacattg gagaggtcca aacatcggtg tggccacaag aggttcgcga
    27061 tacctacgac aatattttat agatgatacg gaggctaggt ttttacctat agcctctatt
    27121 tttgtcccta agtgatgctt cattagagct catttagtgc taagcaggct cgtcagttat
    27181 ataataggtc aaaaatttga aaaaatgaat catttttaag gcttgacact agatttttgt
    27241 tataatatca gttatgagaa ttgtatcagg tgaatttgga gggcgtcccc taaaaacgct
    27301 cgaaggcaag actactcgac ccacatcaga taaggtacgt ggcgcgattt ttaatatgat
    27361 tggtccttat tttaagggcg gacgtgtctt agacttgttt gctggatcag gtggcctatc
    27421 aatagaggct atttctaggg gcatgtcaga ggcagtgctg gttgagcgtg atcgtaaggc
    27481 gcaagccatt atccaagcca atattaagat gacaaaagct agccagcaat ttacgctatt
    27541 aaaaatgaac gctgagcgtg cacttgatca cttatccggt cagtttgatg tggtgttttt
    27601 ggacccacct tatgctaagg aaacgatagt agccaatata gaggccttgg tggagaaaaa
    27661 tcttttaagc gacgatgtga tgattgtttg tgagacggat cggtcggtag ctctgccaga
    27721 ggcaattgcc tggctaggga tctggaaaga aaaacaatat ggaattagca aggtaacagt
    27781 atatgtcagg taagattgga ctttatacag ggtcatttga cccagtgaca aatggacaca
    27841 tggatatgat taagcgtgct agccatttgt ttgagcatgt ttatgtcggg atttttaaca
    27901 atccaaataa gcagagcttt tttacttttg agctgcgagc tcaaatgcta agcgaagcgg
    27961 tttgtgcctt gccaaatgtg acagtggttt ctgccgagca tggtcttgca gttgacctgg
    28021 ctagggagct gtctgtgacc caccttatcc gagggcttcg caatacagct gattttgact
    28081 atgagatagg cttagagtat tttaatcata gactagcccc tgatattgag accatttacc
    28141 tgatggcgac tcatgacctg cagcccgtta gctccagtcg tatcagagag ttgattgcat
    28201 ttagagcgcc aattactggt ttggttccgc aggctgttat taatcaagtg gagaaaatga
    28261 atgaaaacaa taaaaaaaat taaatggtgg ctgattggct ttgttgcctt gctttttcta
    28321 ctgttgacac tgtttttccc cttgccttat tatattgaaa tgccaggtgg agcctatgat
    28381 attcgctcgg tattgactgt caatggcaaa gaggataagg aaaagggagc ttatcagttt
    28441 gttgtagtga gcctcagtcg ggccaccttg gctaaattgc tctatgcttg gctaacgcct
    28501 ttcactgaga ttagcaccat ggaagatact actggtggct atagcgatgc tgactacctg
    28561 cgaattaatc gcttttatat ggaaacctct caaaacagcg ctgtttatca ggcccttact
    28621 ctagcaggca aggaggtaag ctttgattat aagggtgttt atgtcttaga cgtcagcaag
    28681 gattctagct ttaaaggtgt gctgcaccta gcagatacag tgacaggtgt caatggtaaa
    28741 acatttacaa cgtctgccga tctgattgat tatgtttctc atttgacctt gggagatgag
    28801 gtgcaggtac aatttacaac cgctggtgag tcaaagactg aaaaaggaaa gattattaag
    28861 cttaaaaacg gtaaaaatgg gattggcatt accctgacag accacacaca ggtcatttct
    28921 ggtgatgagg tcgactttag cactggaggt gtgggtggac caagtgcagg cttgatgttt
    28981 actcttgata tttatgatca aatcaatcac gaagacttgc gcaagggacg tgtgattgct
    29041 ggtacaggaa ccattggcaa ggatggaaaa gttggagata ttggcggggc gggcctaaag
    29101 gtggctgccg ccgccgctgc tggtgctgat attttctttg ttccaaataa tcctgtgcat
    29161 aaggacgtca aaaaagcaaa tcctaaggct attagcaatt acgaggaggc taaaaaagca
    29221 gctaaacgac taaagacagc aatgaaaatt attcctgtga aaaccgttca agatgctata
    29281 agctacctta aaaaatagaa gcaatgcgaa gcaggctaat agggcatgct ctgtcttgct
    29341 tctagttggt ggaatttagc tagctcaaag gtcttgagac ctaagcataa ggtctagaca
    29401 gtattctaga gctagacctt atgcttgatc ctgaacaagg aagaccgcca aagaagaaca
    29461 aaatcctcag gccaaaagag cccgtaggga aatattgcca ttatctatca aggctttttg
    29521 aagaaaatca cttaaagaca gtagggcgtt aggctttact gtcttagttt ttcttgcctg
    29581 aagtcatggc tgctgatgat gttacatcaa ggcttactag ccagcagagc acaaggagca
    29641 gctttggctt aggtttattt tctctgctga ctagtaaaga aggttgctgt cagtctgctt
    29701 acaaaaacct aaaaatagtg tataataggt aggctatggg ctgtcaggag tcgctagcct
    29761 gcttacccag accagccctt tgagaagagc aagcatggct cttctcagaa taacccagga
    29821 ttaacagaca tcaaaattaa tgctaaggaa aggagctata tgaaaagaga tattttacca
    29881 gagatgtata attacaataa atttcccggt ccggaattta ttcattttga tcattatgtc
    29941 aaggctgaag gcattgagtt attgctgctg aaaaatgaaa aaaatgcttt taacacaacg
    30001 agctttggtc agcgcttcac agagatatta ttaaagtatg actatattgt tggagattgg
    30061 ggcaatgaac agctgcgtct caagggcttt tacaaggatc atcatgatgt caaaaaagct
    30121 agtcgtattt ctcgcctaga agactatatt aaagaatttt gtaactttgg ctgtgcctat
    30181 tttgttttgg aaaaccctaa tcccaaggac atgccaaaag aggaggaaag gccatcaagg
    30241 cgcaggaaat cgtctaaagc caatcgccgc agaaatcagc ctcagcatag tcagcaggca
    30301 cctgctaaag acaacttcaa aaagctaacc aaggataggt cagcggacaa gccaagcttt
    30361 accagcaaaa agcgcccagc tcctaataag accaagggaa accaaaggcg ctctcgtact
    30421 agtcaactga accataaaac ggatcacttt atcatcagaa agaaggacaa ttaatctatg
    30481 aaaccatcaa tctatggcct aacgcgcgac gagctaattg cttgggcgat tgacaatggt
    30541 caaaaggcat tcagagcgac acagatttgg gactggcttt acagaaaacg ggttcaatcc
    30601 tttgatgaaa tgactaacat ttctaaggaa tttgttgcca ttctaaagga cagcttttgt
    30661 attaatccct tgaagcagcg tgttgctcag gaatcagctg atggaacggt taagtatttg
    30721 tttgaattgc cagatggtat gctgattgaa acggttttga tgcgtcagca ctatgggcag
    30781 tcggtctgtg taactacgca ggttggctgt aatataggct gcaccttctg cgctagtggc
    30841 ttgattaaaa agcaacggga tttaaacagt ggtgaaatca ctgcacaaat tatgatggtg
    30901 caaaactatt ttgataagcg tgctcaagac gaacgtgtca gccatgttgt tgtgatgggg
    30961 attggagagc cctttgataa ttatcaaaat gtgatgacct ttcttcggac gatcaatgat
    31021 gatcatgggc ttgctattgg tgctcgtcac attactgttt caacctcagg cttggctcac
    31081 aagattcgtg aatttgccaa tgaaggagtc caagttaatc tggctgtgtc actgcatgca
    31141 cctaataatg agctgcgctc aagtatcatg aggatcaatc gttccttccc acttgataag
    31201 ctcttttcag caatcgaata ttacattgaa acaactaatc gtcgtgtgac ctttgagtat
    31261 atcatgctta ataaggttaa tgatggggta gagcaggcac aggaattggc agatttgacc
    31321 aaaaggattc gcaagctgtc ttatgttaac ctgattccct ataatcctgt ctcagagcat
    31381 gaccaataca gtagaagtcc taaggagcgt gtggcagcct tttatgacat tctaaagaaa
    31441 aatggagtga actgtgtcgt tcgtcaggag catggtacag atattgatgc tgcctgcggt
    31501 cagctgcgct ctaataccat gaaaaaggac cgacaaaaag cagcagctgc aaggacatga
    31561 tgacttggtc aaggttgctg atttgattga taggagatgg agataaaaat ctgacctcaa
    31621 ataaagcaaa caaataggtc tagttttctg agatcccgaa agcaggtctt gttcgttttt
    31681 taatgaatga gactaggtca taaagtacat gcgttaagaa tgtctaaagt gcagctcttt
    31741 ttgtcccagc ctccctcttt tatcttggta gcagttgtca agtaattgct aagcaacagt
    31801 gttttatctt tattggctgt aaaaaaagat atagtgcctt tattcacacc ttttctgaat
    31861 cacttgagcc ttgttctgac cgctcctttt ggtgcttctg atccatatag cctaagcttt
    31921 tcagagctat gaatcgaggc aaaataatag gtgttagccc tagctgcttg atgtagctag
    31981 ggcttttgtg acctagctgc cagtgagcct ttcaaatagc aatatggcta taaggcccag
    32041 tgtcagatag ggaataaaag ggattttctt agtttgtaga agtaggcagg ctagaattcc
    32101 gatcagactg gcaatttgga cgatccataa caaagagcta agcttgacca caagagcaag
    32161 attagctagg taaagaaaat ctccggcacc aatattgata ggaaaagcta cgcttagcag
    32221 tgcaagcaaa agcaatagca ctgttaacag gttaatgcta taaaatggca gcagaaacaa
    32281 aaagctcatc agccagatga gcaaaggata ctcttgactg tctaaatcaa aaaagcacag
    32341 tagcaaagag aagcatagga gataaagctg tgtccaggtc aagccgcaaa gggcagccag
    32401 tccgaaaatg aggctggtga ttatttctaa ataaggaagc ataacccagt gcttttgttc
    32461 atgcttagag ttgtaagtgg gctttgccat aggaaaaaag aggcttgaaa gatgaagttg
    32521 acctatatag agcttgaccc aagcctttgc ttgctgttca gaaaacaggt taagtattag
    32581 ccgaaagagg tttcccacaa gaaaaccaca atagcaataa aaaatagtgt tcatacttat
    32641 ttatccgaaa aacaatttaa attcttgcaa tattttaaaa aacggtgtac aatgaaacta
    32701 taaaacgaga atgattctaa ataagctgtt gatacttatc tgaattggct cgttatcgtc
    32761 gaatggagct gacaagagag tgacttttct tgctgcatac cattcatgcc cttttatatc
    32821 tatcagtaag gagagtttat tatgacaaac acactcgttg aaaacattta tgcatcagta
    32881 actcataata tttctaaaaa agaagcatca aaaaatgaaa aaaccaaggc tgttttaaat
    32941 caagcagtag cagatctatc tgtagcagct tcaattgttc atcaggttca ttggtacatg
    33001 cgtggtcctg gctttttata cctgcaccct aagatggatg agctattaga ccgcttgaac
    33061 gcgaacctag atgagatgag tgagcgcttg attactattg gtggggcacc ctactcaacc
    33121 ctagaggagt tttcacagca ttctaagcta gatgaaacaa agggaagcta tgataagtca
    33181 gtagctcagc atttagctcg tttggtagag gtttaccttt accttaccag tctttatcag
    33241 gttggtttag acattactga tgaagagggt gatgctgctt caaatgattt gttcacagca
    33301 gcaaaggctg acgctgaaaa gactatttgg atgctacagg cagagcgtgg tcaaggtcct
    33361 gctattttct aaagcgtcat acaactgata taacataaaa aaggcagagc gtggtatagc
    33421 cctgtctttt taacgccttt aaagtcagct attagtgcta gtgatgtcag gtctcacagc
    33481 ttttttatga tggatgacca acatttttag accttgtcac cacagcagag catgtggcat
    33541 ttagtccacc ttgggctcac gtcgatggtc ttacttatga tatatcaagg cttgtgacat
    33601 taccgttgcc ttttatcttc agtctgagct gctggttcct actgctgatg ctgcttgata
    33661 gtgttatagt gattttcaga aatatggaaa gcgattgcat aattgtcttg aaatctcatg
    33721 cgtaatttgc taaaatctag ttatatgaaa acattatacg atgtacagca gctgttaaaa
    33781 ggctttggta ttgttatcta catgggaaag cggctttatg atattgaaat gatgaaaata
    33841 gagctgcaaa ggctatatga tggtggcttg ttggataaac aggcttattt aactgctgag
    33901 ctgattttac gacgtgagca tcgattagag ctaaaaagag aagggcaaga aaatgagtca
    33961 aaaattgata gggattgatt tgggcggaac cacgattaaa tttggtattt taacctcaga
    34021 gggtgacgtt caggaaaaat gggcgattga gacaaatgtt ttagaggacg gtaaacatat
    34081 cgttccagat attgtcgcct cactcaagca tcgccttgac ctttatggac tgactaagga
    34141 cgattttatc ggtattggta tgggctcacc tggagctgtc aatcgcacag atcatactgt
    34201 tacaggggcc tttaacctca actggagagg cacccaagag gtgggatctg ttattgaaag
    34261 ggagctagga attccctttg ctattgataa tgacgcaaat gttgcggccc tcggcgagcg
    34321 ctgggtcggt gcaggtgaca ataatcctga tgtggtcttt atgaccttag gaacaggtgt
    34381 tggtggtggt atcatcgctg atgggaactt gattcatggt gtggctggag ctggtggtga
    34441 gattgggcac atgatagtag agccgcttaa gggctttgct tgcacctgtg gctcacaggg
    34501 ctgcctggag acagtggcct ctgctacagg tgttgttaag gttgctcgtc ttttagcaga
    34561 agcctacgaa ggagattcaa gcattaaggc agcgattgat aatggagagg ctgtctcaag
    34621 caaggacatt tttgttgcag cggaggctgg tgatgccttt gccaactctg ttgttgaaaa
    34681 ggtcagttat tatctaggac tggcagcggc taatatctca aatattttga accctgattc
    34741 ggtcgttatt ggcggtggtg tatctgctgc gggtgagttt ttacgttcac gtgttgaaaa
    34801 gtactttatg acctttacct ttccgcaggt tagacagtcc actaaaatca aaatagcaga
    34861 gcttggtaat gatgctggta ttattggtgc agctagcctt gcaagacaat ttatcacaga
    34921 ataggagtta atgatgtcac cacttacaat gattggctgg gtattgcttg cgggagtgat
    34981 tgcctattac ctttggaatt atgtttccta tagaagaatg gcaaagcagg ttgataatga
    35041 tacctttaag gagctgatgc gtcaggggca agtgattgac ctgcgcgatc cagcttcctt
    35101 tagggcaagg catatcctag gcgctagaaa ttttcctgcc cagcagttta ctacctctat
    35161 taaggctttg agaaaggaca agccaatctt gctttatgaa aatgtaagac ctcaatatcg
    35221 ggtcaaagca gtcaaaacat tacgtaaggc tggctatacg gacctttatg tcctaaaagc
    35281 gggactagat tattggaatg gtaaggttaa atagccttat agtccttttt gctgagctaa
    35341 cgtttgctgc tatgtgtcgg aacgttgcaa gcagcagctt atctaagctt gtcatgctag
    35401 tttcacagcc caaagtggct ggccgtataa acgcagctgc ttttagatgc cggtaggagc
    35461 ttttgtcagc ttctttaggg attgttttaa gtgatgtaga gaggccgttc tgagagaaag
    35521 ccttgtagtt agaaaaagag atgagaaagc taaggctctt gctgctgttg taagagttag
    35581 ctttcttttt cttttttgtg tggcgcattt aagggcttga aaacatttac aattccctca
    35641 gatcggtttt ttaaaaaaat ttgtgttata ctgttttagt taaaactatt tatgctacaa
    35701 gaggaaaaaa tgacaaaatt tagagaagat attcgtaacg ttgctattat tgcccacgtt
    35761 gaccatggga aaacaacgct cgttgatgaa ttactaaagc aatcccatac actagatgag
    35821 cgcaaagagc ttcaagaacg tgcgatggat tcaaatgacc ttgaaaaaga gcgtggtatt
    35881 accattcttg ctaaaaatac cgcagtagct tataacgatg ttcgtattaa tatcatggat
    35941 actcctgggc acgctgactt tggaggcgag gttgagcgta tcatgaaaat ggttgatggt
    36001 gttgtccttg ttgttgacgc ttacgaggga accatgcctc aaacacgctt tgtgctgaag
    36061 aaggccttag aacaaaattt aaccccaatc gttgtggtta ataagattga taagccatca
    36121 gctcgtccag ctgaggttgt tgatgaggtt cttgagcttt tcattgagct tggtgcagac
    36181 gatgatcagc tggagttccc tgttgtttac gcttcggcga tcaatggcac atcttcgttg
    36241 tcagatgatc ctgctgatca ggaaaaaaca atggctccga tttttgatac cattatcgat
    36301 catattccag cacctgttga taactcagct gagccccttc aattccaggt gtcacttctt
    36361 gattacaatg attttgtagg tcgtattggg atcggtcgtg tctttcgtgg gactgttaag
    36421 gttggagatc aggtgacgct ttcaaagctt gatggcacca ctaaaaattt ccgcgttact
    36481 aagctgtttg gcttcttcgg gcttgagcgc aaggagattc aagaggccaa ggctggtgac
    36541 ttgattgcag tttctggtat ggaggacatt ttcgttggtg agacgattac accaacggat
    36601 tgtgtggagg ctttgcctgt tcttcgcatt gatgagccga cacttcaaat gaccttcttg
    36661 gttaacaact ctccctttgc tggtcgtgaa ggcaaatggg taacctctcg taaggttgag
    36721 gagcgtttgc ttgtggagct tcaaacagat gtgtcccttc gtgttgagcc aacagaatca
    36781 ccagataaat ggattgtgtc aggtcgtggt gagctgcatc tatctatttt aattgagacc
    36841 atgcgtcgtg agggctatga gcttcaggta tcgcgtccag aggttatcat taaggaaatt
    36901 gatggtgtca agtgtgagcc ttttgaacgt gtacagattg acacaccaga ggaatatcaa
    36961 ggtgctatta tccaatcctt gtcagaacgt aagggggata tgcttgatat gcagatggtt
    37021 ggtaatggtc aaacgcgtct tatttttctc attcctgccc gcggcttgat tggttattcg
    37081 actgaatttt tatcaatgac acgtggctat ggtatcatga atcatacctt tgatcagtat
    37141 ctgccagtgg ttgctggtga gattggtgga cgccatcgtg gagcgctggt ttcgattgaa
    37201 aacggtaagg caacaaccta ctcaatcatg cgtattgaag agcgcggaac aatctttgtt
    37261 aacccaggaa ctgaggttta tgagggcatg attgttggtg aaaattctcg tgacaatgac
    37321 cttggggtta atatcacaac tgctaagcag atgaccaacg ttcgttcagc aacaaaggat
    37381 cagacagctg ttatcaaaac accacgtatt ctaacccttg aggaatctct tgaattcttg
    37441 aatgatgacg aatacatgga ggtaacgcca gaatcaatcc gcttgcgcaa gcaaattttg
    37501 aacaaagcag cgcgtgataa agctaataaa aagaaaaaat cagcagaata aaggctggtt
    37561 ggtctgagca tcacactccc ttgccgcttt aactagtaag ctaggttggc agaggattga
    37621 aaggagcttt ctgtgtttta tcttattatt gcagccttga ttacctctta ttacctgttt
    37681 atggcaccaa agagcgtccg taacacacta ggtatgattg gtttggttgg tttggttgcc
    37741 ctattgattg tgctagctgg cttaagtttt atcaaaatca tgcaaacgcc caaggaaatt
    37801 ttcgttggtc tagccatgat agtattgggc tactatgccc taagggacat tcaaaaaatc
    37861 cctaaaaaac caaagagtaa acattagcat caagcattga gtcaaatctt aatagggttt
    37921 gactttttct gtctttgtac tggccttatg cgctgctatc tgtaaaatct tgaaaaagca
    37981 gttaaataag ggtaaaatag tagtcaaata gacatagata gtgtggataa aaatgaagac
    38041 aataacggaa ttccaaaata aaaaggtatt gattcttggc ctggccaaat cgggcgaagc
    38101 agcagctagg cttttagccc ggttgggagc tattgtgaca gttaatgata gcaagccctt
    38161 tgaggaaaat cccgcagcac aggctcttct tgaggagggc ataagggtta tttgtggtag
    38221 ccaccccttg gagctgttag atgaagactt ttattgtatg gttaaaaacc cagggattcg
    38281 ctatgacaac ccgatggtgg tacgcgcctt agataaggct atttctattc taacagaggt
    38341 tgagctggct tatttggtat ctgaagcacc tatcattggt attacgggct caaatggtaa
    38401 aaccactaca accacaatga ttgctgatgt gctaaatgct gggaaccatt cagctctttt
    38461 ggctgggaat atcggctttc ctgcttcaga ggtggctcaa gctgctacag caaaggatat
    38521 actggtcatg gaattgtctt cctttcagct gctggggact gagcagtttc agccacatat
    38581 tgcagtcatt actaacctag tgcctactca tcttgattat catgggagtt ttgaggacta
    38641 tatagcggcc aagtggcgca ttcaacatcg aatgaccgat aaggattacc ttgtgttaaa
    38701 tgctgatcaa gagctggtaa aatcattggc tcaaaagact aaagcaagtc ctgtcttttt
    38761 ttctaccaaa gaaaaagttg atggtgctta tttggcagat gggtatcttt atttcaaaga
    38821 ggagaggctg atgtcagcag ctgagcttgg tgttcctgga aggcataaca ttgaaaatgc
    38881 tcttgccacc attgctgttg caaagctaag aggcatttct aatcaagtga tatcaaggac
    38941 tttgtctcac tttagggggg tgaagcaccg ccttcagtta gttggtacat tgaatcaagt
    39001 gaccttctac aatgacagca agtcaaccaa tatcttggct tgtcaaaaag ccttgtcggg
    39061 ctttgataat agcaaggtta tcctgattgc tggtggcttg gatcgtggca atgaatttga
    39121 tgagctggtg ccagacctcg ttggtcttaa aaagatgatt cttttagggg aatccgcaga
    39181 gcgtatgaag cgagctgcag acaaggcagg agtgtcctat cttgatgcca aagatgttgc
    39241 agctgccact aaaatagcct ttgagcaggc aaaggctggt gatattatct tgctgagccc
    39301 agccaatgct agctgggata tgtatccaag ctttgaaagc cgcggcgacg agtttttagc
    39361 agcctatgac gcgttaaaag gagaggctca atgaccaaga aaatcatttt taccggtggt
    39421 ggaacagctg gtcatgtcac tttaaacctt atcctcatac cgaagtttat caaagatggc
    39481 tgggaggttc actatattgg tgatgacaaa ggcattgagc atcaggagat caaaaagtca
    39541 ggtcttgatg tcacctttca tgctattgca actggaaaat taaggcgtta tttctcttgg
    39601 caaaacctgc ttgatatctt caaggtaggc tttggtgtca tgcaatcact ttttatcata
    39661 gctagactaa ggcctaaggc tctcttttca aagggaggct ttgtgtcggt tcctcctgtg
    39721 attgctgcaa ggcttttagg ggtgccggcc tttattcatg agtcggatct ttctatgggc
    39781 ttggctaata ggattgctta tcggtttgca acaacgatgt atacaacctt tgagcaagag
    39841 cagacactgg caaagctcaa gcatgttgga gcggttacca aggtgacagg tcctgggagt
    39901 cgatcggtga cttctaagca gcttgaagct gttttggagt attttgatcc taatttaaaa
    39961 acacttttgt ttattggagg ctccgcaggg gctagggtgt ttaaccgctt tatcactgac
    40021 catcctgagc taaaggaaga ctttaatatc atcaatatct ctggcgatcc tagcctaaat
    40081 gagcttagtt ggcatcttta ccgcgtggat tatgtgactg atctgtatca accgctcatg
    40141 gaaatggctg atctggtagt gactcgcgga ggctctaaca cactttttga attattagcg
    40201 atgagaaagc tccagcttat tatcccactt ggcaaagagg ccagtcgagg tgatcagctt
    40261 gagaatgctc attattttac aacaaggggc tatgctgagc aattattgga gcaggaattg
    40321 accctgcctc attttcaaga gaaagtgaga gaagtctttg ctaagcaatc ggactattta
    40381 tctgcaatga agagctctag cgagctccaa tcaccagaaa gcttttacca gcttttaagt
    40441 gccgacatta gctccgcgac aaaggaaaat taaatggcag ataagacaaa acattcagaa
    40501 gaaaaagccg ctttgaccga atggcaaaag cgtaatattg aatttctcaa caagaagcag
    40561 cagcaggctg agaaagacaa aaaactaaaa gaaaaattat taaatgagaa aatagcgcaa
    40621 gctcagggag aggcagcttc aaaggctgac caagaagata cagatgaagc tgaggagaaa
    40681 actgaggtaa gccaagcggg tactgatgag ggtgagccgc tgccagaagc atcagagcag
    40741 gaagtcccct ccccaaaaga caagccatta aaagtcccca aagaaaaaag tccaaagcag
    40801 caggcacttc aaaagggctg gcctgtattg ctggtgtcgt ttgtggtttt gtgcctgtcg
    40861 atttttatga tcacacccta tagtaaggtc aaggatttct ccgtcaaggg caataaaaaa
    40921 acaagcgttg aggacttagt tagagacagt gggatcaagt catctgatta ctggattact
    40981 ctattagcct ctccgggttc ttatgaaaat gcggttttaa aagccaatcc ctgggtgaaa
    41041 aaggtggctt tgcgttacgg ctttcccaat catttccgct ttgatgtgac agagtttgat
    41101 attattgcct acgctcaggt agctgaaggg tttcaactga tcctagaaaa tggcaagcga
    41161 gttgctgctg tcaagcaggc tgctttgcct aaatcctttt tgattttaaa tcttgagcat
    41221 gaaaaagaga ttcaagatgt cattaatcgc ttgaccaaaa tcccaagtga cctagtcaag
    41281 gctatcaaat cagtgtcatc ggccaattca cagacaacta aggatttgct gcttcttgaa
    41341 atgcacgatg gcaaccttat cagggtacct cggtcacagc ttgagctaaa gctgccttat
    41401 taccaaaaaa tcaagaagaa tcttgatact gctagcattg ttgatatgga ggttggtatc
    41461 tatacgacca ctgctgaaat tgaaaacatg cctgaggtgc cagcgtctgc tcaagcttct
    41521 caggcagata agcctgctga ggcttcacca gagcagggtg aagagcaggc cacacaggag
    41581 cagcctagcc ctgaaacacc tgctaatcct gaggccacaa atccctcagt cgcccagcct
    41641 actgagcagg caaatcaaca gtaatcgttt agggtaagag aagggggcaa aaaagcattt
    41701 aaggctctta aattaggccc ttgttgaacg gcaaaaaaac attaagttta tataacaaaa
    41761 aacgtaaaat ggtaacattt tacgtttttt tatgatataa tattccctga ataattctgc
    41821 tttttagcag tgtttttgaa tagtaaaagt ttggaaagta agtgaggtcg agtgaatggc
    41881 tagaaatggc ttttttactg gtttggacat tggaacaagc tcgataaagg ttttggtagc
    41941 agagtttatc tctggcgaga tgaatgttat tggtgtgagc aatgttccga gtactggcgt
    42001 aaaagatggc ataatcattg atatagaggc agcagccgct gctattaaaa ctgcagtaga
    42061 acaagctgaa gaaaaagcag gaatgacaat tgaaagggtc aatgttgggc tgccagcaaa
    42121 cctccttcaa attgagccga cacaaggcat gattcctgtt cctagcgaat caaaagaaat
    42181 caaagatgaa gacgttgata gcgttgttaa gtcagcacta actaagagca ttactccaga
    42241 gcgagaggtg atttccttag tccctgaaga gtttattgta gacggctttc agggcattcg
    42301 agatcctcgt ggcatgatgg ggatcaggct tgaaatgcgc ggtctgattt acactggacc
    42361 aagcacaatc ctgcataact taagaaagac agttgagcgt gctgggatta aggttgaaaa
    42421 catcatcatt tctcctttgg caatggctaa ggcggtgtta aatgaaggtg aacgtgaatt
    42481 tggtgctacg gtcattgaca tgggtggagg acaaaccacc gttgcctcaa tgcgagcaca
    42541 ggaattgcag tacaccaata tctatgcaga gggtggcgag tatatcacaa aggatatctc
    42601 taaggttctt aaaacgtcaa tgtcaattgc agaggccttg aagtacaatt ttgggcaggc
    42661 tgatatggca gaggcaagct tgactgacac tgttaaggtt gatgttgttg gcagtgatga
    42721 gccagttgag gtaacagagc gttacttatc agagattatc tcggctcgtg ttcgccatat
    42781 tctagatcgt gttaagcagg atttagaaag aggacgcctg cttgatttac ctggtggcat
    42841 tgtgctgata ggtggcggcg ccattatgcc gggcgtggtt gaggttgctc aagagatttt
    42901 tggaaccaat gttaagcttc atattccaaa tcaggttggt attcgtaacc caatgtttgc
    42961 caatgtcatt agcttggtcg agtacgttgg tatgatgtca gaggtggacg ttttagcgca
    43021 aaatgctgta tcaggcgagg aattgctaag acgtaagccg atcgacttta ctggccaaga
    43081 agcttacttg ccagactaca atgagactag gggatttgaa ccggctccta attatgagca
    43141 gcaagtgccc caagcagact acgagcctca agaacccgct gaaccaaagc aaaagatttc
    43201 agagcgtgtt cgtggcattt ttggaagtat gtttgattaa aagtaataaa gtgaggaaat
    43261 aaaatggcat tttcatttga tacggcatcc attcaaggtg caatcattaa ggtaatcggt
    43321 gttggtggag gtggcggaaa cgctattaac cgcatgattg atgagggggt tgcaggtgtt
    43381 gagtttatcg ctgcaaacac tgatattcag gcattaagct catcaaaagc agaaacagtt
    43441 gttcagcttg gtcctaaatt aactcgtggt cttggtgctg gaggtcagcc agaggttggt
    43501 cgtaaggcag cagaggaaag cgaagaggtt ctcacagaag ctttgactgg cgctgatatg
    43561 gtctttatca ctgctggtat gggtggaggc tctggaacag gagcagctcc agtgattgct
    43621 cgtatcgcta agagcctagg agccttgact gtggcagttg taacacgtcc atttggcttt
    43681 gaaggcaaca aacgcagtaa ttttgccatt gaggggattc aggagctaag agagcaggtt
    43741 gataccttat tgatcatctc aaataataac ctgcttgaaa ttgttgacaa aaagacacca
    43801 ttgcttgaag cgcttagcga agcagacaat gttttgcgtc agggtgtaca agggattact
    43861 gatctgatta caagccctgg cttgattaat cttgactttg ccgatgttaa gactgtgatg
    43921 gcaaataaag gcaatgcact tatggggatc ggtattggtt ctggtgagga acgtattgta
    43981 gaggcagctc gtaaggctat ctactcacca ttacttgaaa caacaattga cggtgctgaa
    44041 gatgttatcg ttaacgtgac aggtggactt gatatgaccc tcacagaggc tgaggaggca
    44101 tctgaaattg ttggtcaggc agcaggtcaa ggcgttaaca tctggctagg aacatcgatt
    44161 gatgactcta tgagagacga aattcgcgta acagttgttg caacaggtgt tcgtcaggat
    44221 aaggcggagc aagcctcagg atttcgtcag ccacgcacct acactcagtc taacgctcag
    44281 caggctgctg gagcacaata tgcttcagag caggtgagac agactgcgca gccaagcttt
    44341 gatcgtcgtt catcaagctt tgattttgat atgggtgaaa cacgtgagat gcctaagtct
    44401 cagcaagcta tgccagctca tggccacaat cataatcagg gctcagcttt tggaaattgg
    44461 gacttacgtc gagacaatat tgctcgtcca gcagaaggtg agcttgacaa tcaattgaac
    44521 atgtcaacct tctcatcaaa tgatgacatt gatgatgaat tagaaacacc accatttttc
    44581 aaaaatcgtt aatgatggat ttacaaaaaa ataaggatat tgtttttgaa aatattcgct
    44641 tagccactca ggcagccaac cggcctgaaa acagtgtgtc agttatcgct gtcacaaaat
    44701 atgtggacaa ggcagttgca ggtcagctga ttgatatggg gattgagcat atcgctgaga
    44761 accgtattga taagtttcta gataaatatg aagccttgaa agataggcaa gttacttggc
    44821 attttatcgg tactttacag cgtcgaaagg taaaggaagt gattaataag gttgattatt
    44881 ttcatgcctt agattcagta aaactggctt tagaaattga aaagagagct gaccaccctg
    44941 tgaagtgttt tctacaagtt aatatttctg aagaagaaag caagcatggt tttaagattg
    45001 ctgagcttga tgctgctatt gaggaaatca gcaagatgga aaagcttcat cttgtcggta
    45061 tcatgacaat ggcacctatt gatgccagtc agcaagagct tagaagcatt ttccaaaaag
    45121 caaatcaatt aagaaaaaac ttgcagtcaa aaaagagaaa gaatatgccg tttacagaat
    45181 tgagtatggg catgagtaac gattatccaa ttgctattca agaaggctca acctttgttc
    45241 gtattggaac atctttcttt cactaaatgg agaataagat ggcaattaaa gacgcattta
    45301 ataagatgat ttcttatttt gatactgatg gggtcagtga agtagaagag gagctatcct
    45361 ctaaaaagca agaagagcct gtgactaaat cacaacagac cagcagacct aatcagcagc
    45421 aacaagcagc tagagcgagt cagccccagc agcctaagca ggctagacct cagatgcaag
    45481 ctcagcaaag accacaatca caatcaagag ctgcctatgc tgagcgacca tatcaaggtc
    45541 aaagtcaagc acgtgtttct catgactaca atgacagaag ggcgacgtca gccccgtctg
    45601 cttctagtcg tcgtgagcaa tatcagcatg ctgctcatca agagcaaaca actattgcct
    45661 tgaagtatcc tcgtaagtat gaggacgccc aagaaattgt tgatcttttg attgttaatg
    45721 agtgtgtgct gatcgatttt caatacatgc tagatgctca ggcaaggcgt tgcctagatt
    45781 ttattgacgg tgctagtaag gtattgtatg gtactctgca aagggttggt tcttccatgt
    45841 atctgttgac cccatcaaat gtatctgtta atattgaaga gatgaatatc ccaaataatg
    45901 gccaagatat tggttttgat tttgatatga agagacgcta gtgtgatgat ttttatactg
    45961 ttgatacttc taaagctaat taaggtttat tcctatttgc tgctagtcta tgccttactg
    46021 tcttggtttc ctggagccta cgactcttgg cttggcaggc tggtcagcga tatagtagag
    46081 cctatcttaa aaccctttag atcattgaac ctacagtttg cgggcttgga ctttactatt
    46141 tacctagtga tgattggtct aaatgtttta agtgagatct tgataagagt gttgatctca
    46201 tgactgttca aacaatgctt tatcagcatt ttcagcctga tgaacaccca tttattgaaa
    46261 gaatgcttga cttgatcgct cgtgttgagg ctaattattt attagaggtt actgattttt
    46321 taaatccgcg agaggtcacg attttaaaag gcttagtcgc agcaaccaat ctgcagtgct
    46381 ttagctctac tgattattat cctagtgaat atggtcgtgt gattgttgct cctgactatt
    46441 attgtctaga taaggcagat tttgacttgg ctttgattga ggtgacctat aatgctaagt
    46501 ttaatcagct gacacatgca cagattttag gcaccttaat taatgaattg ggaatcaaaa
    46561 gagccttact tggcgatatt tttgttgaga taggtcatgc tcaggtcatg attaatcgac
    46621 agctgttaag ctattgttta ggaacgattg ctaaaatagc aaaagctagg gtcaagctca
    46681 aagaaattga tcttgatcag ctgttaaatc tgacagctaa tcagcaggtt ctgactgata
    46741 taatggtatc tagtctacgc gttgatcgct tgattgctac cgtattaaag caatctagaa
    46801 atcaggcgat aaggcttgtt gaagcaggca aggtcaaggt taactatcag cttgtcacta
    46861 aagcctctca gcctgtagct gttggtgatt taatcagcat tcgtggctac ggtaggttta
    46921 gcatactaac agacaatggc ttcacaaaaa atgggaaata taagctaaca cttagcaaaa
    46981 tgatgcgtaa ataaggagat ataatggcac ttacagcact agaaattaaa gataaaacgt
    47041 ttaagacaaa gtttcgtggc tacagtgaag aggaagtaaa tgaatttctt gagattgttg
    47101 tagacgatta tgaggctttg gttcgcaaaa atcgtgataa tgaagctaag ataagagagc
    47161 ttgaagaaaa gctgtcttac tttgatgaga tgaaggaatc attgagtcaa tctgttatcc
    47221 tagcccagga aacagctgaa aaagtgaaat cctcagcaaa tgctgaagca accaatttgg
    47281 tcagcaaggc aacctatgat gctcagcatt tacttgatga gtcaaaagca aaggctaacc
    47341 aactgttgcg cgacgcaaca gatgaagcaa agcgcgttgc tattgagaca gaggaattaa
    47401 agcgccagac acgcgttttc catcagcgct tggtttcagc tattgagtca cagctaagct
    47461 tatccaattc gcctgagtgg gacgaattgt tgcagccaac agctgtctac cttcaaaact
    47521 ctgatgcagc ctttaaagag gtggttaaaa ctgtccttaa tgaagatatt cctgaggctg
    47581 atgacagcaa ttcctttgat gcaacacgtc agtttacacc agaggagcta gaggagctgc
    47641 agcgtcgtgt tgaagaaagc aataaggagc tagaagccta tcaggtgcag cgagaagagc
    47701 aagctagcga gcctgaagtg aacctaagcg agacacagac ctttaaattg aatatttaat
    47761 cataagaaaa acaggattga atgcccaaaa tcacagcaag taggagatga tgagagtcct
    47821 atattccctg agcatgacaa ttatcatttt cttcaatcat cactgaatga cagtaagtga
    47881 cgagggaggc tcaccttacg agcaaagagg gaacagcaaa agggatttta ctgttctgaa
    47941 ttaaggtggt accacgagct ttcgtccttt ttgagacggg gctttttttg taattctgat
    48001 aagatattga ctaaaaggag tttgacaaga tgaaattaaa agaaacactt aacttaggca
    48061 aaacggcctt tccaatgcgt gccggtctac ccaacaagga gccacaatgg caaaaggctt
    48121 gggacgaggc tgagatttac aaaaaacgtc aagccttaaa tgaaggcaag cctgcctttc
    48181 acctgcacga tgggcctccc tatgcaaatg gtaatatcca tgtcggacat gcgctgaata
    48241 aaatttcaaa agacattatt gtacgtgcca aatctatgtc aggctatcaa gcgccttttg
    48301 ttccaggttg ggatactcat ggccttccta ttgagcaggt cttggctaag cagggggtta
    48361 agcgtaaaga gatggatctg gctgactatc ttgacatgtg tcgtcagtac gcgttaagtc
    48421 aggttgataa gcaaagagac gactttaagc gtctcggtgt atctgctgat tgggacaatc
    48481 cttatgttac cttagatcca agctttgaag ccgatcaaat tcgtgtcttt ggtgcgatgg
    48541 ctgataaggg ctacatttat cgtggggcaa agcctgtgta ttggtcatgg tcctctgaat
    48601 ctgctcttgc tgaggcagaa atcgaatacc atgatattga ttctacatcg ctttactatg
    48661 ctaatagggt taaagatggt aagggaatcc ttgatactga cacctatgtt gtggtttgga
    48721 cgaccacacc atttacggta acagcttctc gtggtctaac agttggacct gatatggatt
    48781 atgtggttgt tagacctgca ggttcagacc gtaactatgt ggtggcagaa ggactgctag
    48841 acagtctggc tgctaagttt gcttgggaat catttgagat tttggccaat cataagggct
    48901 ctgacttgga atacattgta accgagcacc cttgggacag tgaggttgat gagctagtca
    48961 ttcttggcga tcatgtgacg ctagattcag gtacaggtat cgttcataca gcacctggct
    49021 ttggtgaaga tgactacaac gttggtatga catatggact tgaggttgca gttacagttg
    49081 atgagcgtgg tttgatgatg gaaaatgcag gtcctgattt tcatggtcaa ttttatggca
    49141 aggtaactcc gattgttatt gaaaagcttg gagacctatt gcttgctcaa gaagtgatca
    49201 accactccta tccatttgat tggcgcacga aaaaaccaat tatttggcgg gctgttcctc
    49261 agtggtttgc ttctgtgtct gacttccgtc aagagattct agatgagatt gacaaaacaa
    49321 cattccaccc gacatgggga aagacacgac tctacaatat gattcgtgat cgtggcgatt
    49381 gggtgatctc tcgtcagcgt gcttggggtg ttccactgcc tattttctat gcagaggacg
    49441 gcacagccat tatgactaag gaggtaactg atcacgtcgc agatctgttc caagagcatg
    49501 ggtccattat ttggtggcaa aaagaggcta aggagctttt acctgaaggc ttcacacacc
    49561 caggctctcc aaatggggta tttaccaaag agacagatat catggacgtc tggtttgatt
    49621 cagggtcttc ttggaatggt gtgatgaatg ctcgtgatca tcttgcttat ccagctgacc
    49681 tctaccttga gggctccgat caatatcgtg gttggttcaa ctcatcactg attacctcag
    49741 ttgcggttaa tggtcatgca ccgtataagg ctatcctatc acagggcttt gtccttgatg
    49801 gtaagggtga aaaaatgtct aaatctaaag gaaatatcat ttcacctaat gatgttgcaa
    49861 agcaatatgg tgctgatatt ctccgtctct gggtagcttc tgttgataca gataatgatg
    49921 tgcgtgtgtc aatggatatc ctaggacagg tctctgaaac ctatcgtaaa atccgtaaca
    49981 cgcttcgctt cttgcttgct aatacatcag acttcaatcc acatacagat aaggtggctt
    50041 atgctgagct tgctgctgtt gataagtaca tgaccatcaa gtttaacaag ctagtaggag
    50101 ctatcaatac tgcctatgag cgttatgact tcatgacgat ttacaaggct gtggttaact
    50161 ttgtgacggt tgacttatct gctttctacc ttgattttgc caaagatgtg gtctacattg
    50221 aggctgctaa cagcctggca cgtcgtcgta tgcagactgt cttttatgat attttggtta
    50281 atatcactaa gctattgact ccgatccttc cacatacggc agaggaaatc tggtcatatt
    50341 tagagcatga gccagaagac tttgtacagc tatcagagct gccacaggct cagacttttg
    50401 ataatcaaga tactatccta gaggaatggg aagcctttat gacgcttcgg gcacaggcgc
    50461 aaaaggcttt ggaggaagca cgtcatgaca agattattgg taagtcctta gaagctcatc
    50521 tgacaattta tgcaagtcca gaggttaaga cactgttgac agctctagat agcgatattg
    50581 cactgctatt gattgtctct cagctaacca ttagtgagga gccagctcct gagaatgctg
    50641 tcagctttga tgatgttgcc tttacggtag ctcgtgcgca aggagaggtt tgtgagcgtt
    50701 cacgtcgtat cgatccaacg accagaatgc ggtcttataa tgcctttgtt tgtgaccaca
    50761 gtgcgaaaat tatcgaagaa aacttcccag aagcagtagc agaaggcttt gactcagctg
    50821 ctaattaagc aactaacagc tctgttcccg agttaaataa gcattggcgt gcttttgcca
    50881 atccagcagc aaggtgctag tcggtctggg cgtacctgcc ttactaggga ctctttgtgt
    50941 gggagctgat aagtgacctg ccttgagctt ggcaggtcta ggcttcttta taggttcacg
    51001 atttacgatt gactgggctt agagaagggc tagtcctgct aggcggcatt ggatatgaac
    51061 tgagtagtca tcatagctat aaaaaaacaa gcgcagactc acgtcagctt aatcgtgagc
    51121 ggcgcttgtt ttttcttggt tggggggtga aggcgaggag ctattaaagc taatattaag
    51181 cgatcaaaaa agcctagacc actagtcatg ttgtctaagc ttcagctgtt agagaggagc
    51241 tttctgagtg gaaggtagcc tatgctgata ggtgctgcct tagcctttta gcagtagtat
    51301 taaggctaga cagacgtctg gaaggaaatt tcaatcaaat tattggtgtg cagggttttt
    51361 gagtgacctg gaatcacaat agattggtca atcttacgct ttaagaaaaa ttcgcgaatc
    51421 acttcaagct cgtcctcttt gatggcacga tatttatttg aaatgagtag ctcataatgc
    51481 ttgggtgctt gcgtaaagat gacgtcagtg ttaccagctg agtaaacttc aacgaggtga
    51541 gcatctgtat tttgcagctg atttctgaca agctcggggt gactgctggt ggtattaata
    51601 agtctcataa atcttctcct gactattttt acttttatta tagcactatt tttaaattga
    51661 ttacggattt taatggtgct ttttctgcca ttcttcgacg ccccatctgt ggctatcacg
    51721 ctttaagact gttatggcgt ccgcaatagg aagaaaccaa gccagatggt taaagtcttc
    51781 caagggcttt gagatagctt ggaatgatgt cacctcgtac aggtaggcag gattatagta
    51841 gtaggtatcg cggtgacgag aatagaagta ttcgtctgct tgaccataat aataaccaat
    51901 atcagcagca aatcccagct cctcaactag ctcacgctcc agtgcctgta gctggctttc
    51961 accagcctct atttctcctc ctggcaaaaa ccaagcacca tttggagcct gcactaggat
    52021 aatctctgtt ttagccgagt taggaatcac tgcatagaca ccgtaacgtg cggtgtaatg
    52081 ctggtcatct atcttatcac caaatattgg aacggtcata tcgcttctcc tttgttttat
    52141 tatactaaat ttttggtcat tattctcata aaactgtaga tttatcaaaa atgtttcata
    52201 aaaaaatgct cgtcaaaaag agagaaaatg ctgtctgctt ttctctctgc ttttctctct
    52261 gctttttggt atgccctgtt agtccgcctg cttcgcctga gatttgacta caggcttgat
    52321 tataatgtgt ccattagagg tcaagacagc tcgcatgtct ttttctgctg ggtgctcaag
    52381 gtagaagtca gtaatggcgt cctcaatgta gtcctgaatg gtgcggcgca atggtcgtgc
    52441 tcccatctta ggatcatagc ctagctcaac gagcttttct ttgacctttt gggtgacatc
    52501 aaggcgaatg ttattgtgag caaggcggtg gttaacatca tcgagcatta aatgaacgat
    52561 atgtaaaaga ttgtccttgc ttagtggctg aaactcaata atgccatcaa agcgattcat
    52621 gaactcgggg ctaaagaaat gactgagctc tcctaaaaca gagtttgtcc gcccttctct
    52681 agcagcgcca aagcctactg aggcctctgt tttgccagtg ccagcatttg atgtcatgat
    52741 gataatagtg tccttaaagc taacggtacg tccttgtccg tcggttaatc gtccgtcatc
    52801 taggacctgt aaaaacatgt gcatgacatc agggtgagcc ttttcgatct catctaacaa
    52861 aatgagcgag taagggttgc ggcgcacctg ctctgttaac tgacctgcct cctcatagcc
    52921 gacgtagccg ggaggggcac cgacaagctt agccacagcg tgcttttcca tgtattcaga
    52981 catgtcaaag cgaatcatgt tatcagcaga gccaaaaagc tcaatggcta attgcttgga
    53041 aagctctgtt ttaccgacac cagttgggcc aacaaagagg aaggagccga taggacgatt
    53101 tggggctccc agtccaacac gattacgacg gatagctttt gcaattttat caacagcatc
    53161 gtcttgaccg ataacatgct ttttgagatc ggcggccaga ttgactagct gtgattgttc
    53221 cttttccttt aaatcaccaa ctggaatatt ggttttttgc tcaacgattg cttcgatggt
    53281 cttgtcagtg atgattggaa tatcctgctc atctagcttt tgagcctgca tttctttata
    53341 tttggcgatt tgatcgcgga aataggctgc tcgctcataa tcctcatcac gtgtggcttg
    53401 tgtcttgagg ttttcagcct caatcaaacg cttatcaatg tctttggggt caacaaagtt
    53461 aagggttagg ttcatctttg agccggcttc atctagcagg tcaatggcct tatcaggcaa
    53521 gaagcggtct tgaatatagc ggttggagag gttagcagct gcttcaatag ccgactggct
    53581 atatttgaca tggtgatagt cctcatattt gggttggatt ccttttagga tagtgattgt
    53641 ttcttcaacc gaaggctcgt ccaccttaac cggctgcatg cgtcgctcaa gggctgcgtc
    53701 cttttcgatg atgcgatatt cattgagagt ggtcgctccc actaattgaa gctcaccacg
    53761 agcaagtgct ggctttaaaa tatttcctgc gtccatgctg ccgtcaccaa ctgcaccagc
    53821 tcccacaatt tcatggattt catcaataaa tagaatcacg tcatggcgct tgcggatttc
    53881 ctccatgagc ttttgcatgc gctcttcaaa ttggccacga atacctgtcc cctgaacgag
    53941 gctaaccaca tcaaggcgaa tcacctgctt actctgtagc ttttgtggca catcgccatc
    54001 aacgattttt tgagcaaggc cttcaacgac agcagtctta ccaacacctg gttctccgat
    54061 taggacaggg ttatttttgg tacgacggtt gagaatctcg atcacgcgga taatctcatc
    54121 gtcacgtccg atgacaggat caatatcacc acgcttagcc atttcagtga tattaatgcc
    54181 gaattcctca agcaaacctt tgttagcctc ttgtgctggc tgtgtgtgat tgggacggta
    54241 gccattgtga cctccgccat tatggccgcc tgattgggta ggtggtgtat tgggcaattg
    54301 accgaaggct ctaaaattgt tcaggtcacc aaaaaagtca tcaaagaaag ggttttgaga
    54361 aggctgctgc gccttttggt tgccattata gcctcctaag ataggatttt tagggtctgt
    54421 tttcatgatt tggtagcaat tttgacagag gtcaatctgc ctttgctttc cgttaatgct
    54481 tgtataaaga tgaatggttg attcgtttaa attacagttt tgacaaagca tatcatacct
    54541 ccaaggggtt atctaaaaag tcaaggtcat ttagtcaaaa atggtcaaac tttatagtca
    54601 tattatagca ccttaggctt ggaaatcaag taaaaagctt cattattagc actttcaggt
    54661 atagagtgat aatctctata aatcttgctg ctcattggtt caaaaaagtc gtcaaagggg
    54721 ataaaataaa gagaaaatgg ctacttttct tgtttgtttt cgatgattta tgttaaaata
    54781 tatagggaca ataaacgaat aggagaaacg aaatggaatc acatttagtg agaatcatca
    54841 accgtctgga gctgatggta acagatggcg gtaatttaaa gagaaacttt gagcgagatg
    54901 gtgttgttgt tgcagaggtt gcatttgtca acgatcctga aaatggtcca gtctttattt
    54961 tacgtgatat tgaagcgcgt gagtcatatt catttgatag catcgatttg attgcgatgg
    55021 aaatttacga tttgttatat taagctattg atgatgacat gggcttgctg ggaggcaggt
    55081 cagacagagg acaagctggt gatttactgg tttgttttta ttatccctta aagcctcaag
    55141 acagctccag gaaaggcctt tctcctatgg tctttctagc cggtagggct tgatagtgat
    55201 taatagtgat ctgctctagc acggtcttga gcttttactg tcagaggctt gtgaccttag
    55261 ccactcgcag taaagggtac tggcccagta agcaaggtag gctaagtatc aatgtgaagt
    55321 tctaaccttg atcttagtga aatatttttg aggtgaatta agatgttaaa agtccttaga
    55381 atgctcattt ctaagggttt tgttgtgtct agctgttggt gtttgaaaga gcggtggtat
    55441 gataaagaga ggtcagaaaa gacctctctg atgtttgtga ttagctgtta gctattgcca
    55501 taggggaaag acacaatagc tagcttagct tttctttttc tttaggttta ggacgcctgc
    55561 gctagtgatg acgctaaggg ctgcaagggt gaagaatggg tgatttgtct cccctgtagc
    55621 tggtagcgtg ctcttttgag ctgctggtgc tgacttaggc gctggtgctt taggctgagc
    55681 tgatttttct ggagcctttg gtgcaggtgt cttttcaggt gcttttggag ctgatggttt
    55741 tgtatctttt ccttgatcac cctttggttt ttgctcgcct ttttcgccgc gttgtccttg
    55801 ctcgcctttt tc
//
LOCUS       DARYXZ010000005        53532 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYXZ010000005 DARYXZ010000000
VERSION     DARYXZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53532
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(4..780)
                     /locus_tag="TV186_000230"
     CDS             complement(4..780)
                     /locus_tag="TV186_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HEL1531665.1"
                     /translation="MNEIFNFKGQEVRAVTINGEPYFVGKDVASILGYSNSRKALLDH
                     VDEDDKTDGVTIRDSMGREQTPVVINESGLYSLILSSKLPQAKEFKRWVTSEVLPAVR
                     KHGMYAVGDLLDNPDMAIAAFQRLKEERQLRLQAQEEVAQKNQIISEMKPKATYYDLI
                     LQSDSLVAITVIAKDYGKSARWLNTLLHELKVQYRQGNTWLLYQQYADRGYTQSKTHT
                     IDAERSKMHTYWTQKGRLFIYDLLKNKKGILPKIEQEDVA"
     gene            complement(782..967)
                     /locus_tag="TV186_000231"
     CDS             complement(782..967)
                     /locus_tag="TV186_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1531666.1"
                     /translation="MICGKIKAIASEKNISIYRIERDLSLSNGSIGKWNKSIPSVTTL
                     KSVADYLRVPLEKLLED"
     gene            complement(969..1178)
                     /locus_tag="TV186_000232"
     CDS             complement(969..1178)
                     /locus_tag="TV186_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016356210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEL1531667.1"
                     /translation="MSKQQELWLDLVEQKMEEFGWKNVQLARAVGVKSPTITELLKYG
                     KGSDRLKNKVCDVLRIDESWTSLGE"
     gene            1465..1809
                     /locus_tag="TV186_000233"
     CDS             1465..1809
                     /locus_tag="TV186_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1531668.1"
                     /translation="MFLTFEKIKELAKKQGLSLNDLEEKLGVGKNSLYGLKRNQPSAE
                     RLQQIADYFHVSTDYLLGRTNNPNIADDKKETFSARGRAIARKYDSASPKKQKYYDRM
                     IAAMFEDDEEDD"
     gene            1810..2892
                     /locus_tag="TV186_000234"
     CDS             1810..2892
                     /locus_tag="TV186_000234"
                     /inference="COORDINATES: protein motif:HMM:NF017885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1531669.1"
                     /translation="MKIPSSPRYKFATHMALETFTYFNVLSFPIDVKALIKSEGIRLK
                     KYSTIAKRVGISLDEVCKEYQTDLAYIFRQSSGEYAIAYNDTKPEYVIRFSLAHELGH
                     YALMHLEDFDETILRYRGNGLVEKKYQVLEKEANCFARNLVSPAPVADVIPQEMYQLY
                     FGIGYGAEQTRINLLRSDKYYTKLLNSDIGKKHFSRLRRRISHTHKCLNCKACVVRKK
                     INFCPICQSDELKKLDLRELMDLERQGKIMKYSSIELGENKFPIRCPRCENEDINSSE
                     KFCPICCTYLKNICIGKGPFYEDADELYPSFPIDRENNGCGKELIGSARYCSDCGGIS
                     SYFNQGLLSFWVNEKEKYDILGEMPF"
     gene            2919..3407
                     /locus_tag="TV186_000235"
     CDS             2919..3407
                     /locus_tag="TV186_000235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531670.1"
                     /translation="MKRIIYLFMLLLSVTYLAACSNSSTKGGDFKTYIKNTDFKSIEH
                     DSINNLYIVSQDLNTIISDENAINSFNDSIYDVLQLGFKTDKDIIFRGWDGNLAGSLV
                     YFDKDTFNQKWGVSDSNKIYNKSSGWQTISKFNQYLDSKNSAKTPEIEERLFELAMYS
                     KK"
     gene            3527..4606
                     /locus_tag="TV186_000236"
     CDS             3527..4606
                     /locus_tag="TV186_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1531671.1"
                     /translation="MAFYRKLDSGWEYRITYRDSQGKKREKSKRGFKTKTLAKVAAQQ
                     AETDLNTLTADLLDITVLDYNKRWADIYKRPHITAKTWQTYTKNFKHIEHYFGTRKLK
                     SITHTFYQQVLNDFGEKVAQQTLDKFHYQIKGACKMAIRDGIIRDNFADEAIVRSQKP
                     AKEESEKFMEESEYLAFIKTAKEKIKYPSYLTTYIIAITGLRFAEAQGLTWKDIDFDN
                     GYVDVNKTFDYSISQNFRPTKNEQSIRKVPIDNNSVELLKYFKDNHYQDNKLSRICFG
                     ASNNATNKVIKRVTGRNLTNHSLRHTYASYLIAQGVDLISVSKLLGHENLNITLKVYA
                     HQIESLKEKNDHQVKNIFQNLKFDG"
     gene            complement(4653..4739)
                     /locus_tag="TV186_000237"
     tRNA            complement(4653..4739)
                     /locus_tag="TV186_000237"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4703..4705),aa:Ser,seq:gga)
     gene            complement(4799..5434)
                     /gene="trmB"
                     /locus_tag="TV186_000238"
     CDS             complement(4799..5434)
                     /gene="trmB"
                     /locus_tag="TV186_000238"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL1531672.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            complement(5434..6225)
                     /locus_tag="TV186_000239"
     CDS             complement(5434..6225)
                     /locus_tag="TV186_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL1531673.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(6288..7322)
                     /locus_tag="TV186_000240"
     CDS             complement(6288..7322)
                     /locus_tag="TV186_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531674.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(7326..8051)
                     /locus_tag="TV186_000241"
     CDS             complement(7326..8051)
                     /locus_tag="TV186_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1531675.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            8588..9031
                     /locus_tag="TV186_000242"
     CDS             8588..9031
                     /locus_tag="TV186_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531676.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            9484..9903
                     /locus_tag="TV186_000243"
     CDS             9484..9903
                     /locus_tag="TV186_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL1531677.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            9900..10196
                     /locus_tag="TV186_000244"
     CDS             9900..10196
                     /locus_tag="TV186_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL1531678.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(10366..11628)
                     /locus_tag="TV186_000245"
     CDS             complement(10366..11628)
                     /locus_tag="TV186_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1531679.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(11629..12156)
                     /locus_tag="TV186_000246"
     CDS             complement(11629..12156)
                     /locus_tag="TV186_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1531680.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(12149..12592)
                     /gene="tsaE"
                     /locus_tag="TV186_000247"
     CDS             complement(12149..12592)
                     /gene="tsaE"
                     /locus_tag="TV186_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL1531681.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            complement(12958..14418)
                     /locus_tag="TV186_000248"
     CDS             complement(12958..14418)
                     /locus_tag="TV186_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL1531682.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            14677..15488
                     /locus_tag="TV186_000249"
                     /pseudo
     CDS             14677..15488
                     /locus_tag="TV186_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            15840..16832
                     /gene="manX"
                     /locus_tag="TV186_000250"
     CDS             15840..16832
                     /gene="manX"
                     /locus_tag="TV186_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL1531683.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            17003..17812
                     /locus_tag="TV186_000251"
     CDS             17003..17812
                     /locus_tag="TV186_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL1531684.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            17828..18739
                     /locus_tag="TV186_000252"
     CDS             17828..18739
                     /locus_tag="TV186_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1531685.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            18873..19256
                     /locus_tag="TV186_000253"
     CDS             18873..19256
                     /locus_tag="TV186_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL1531686.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(19577..20629)
                     /locus_tag="TV186_000254"
     CDS             complement(19577..20629)
                     /locus_tag="TV186_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL1531687.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            21229..22506
                     /gene="serS"
                     /locus_tag="TV186_000255"
     CDS             21229..22506
                     /gene="serS"
                     /locus_tag="TV186_000255"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL1531688.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            complement(22738..23508)
                     /locus_tag="TV186_000256"
     CDS             complement(22738..23508)
                     /locus_tag="TV186_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL1531689.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(23505..24371)
                     /locus_tag="TV186_000257"
     CDS             complement(23505..24371)
                     /locus_tag="TV186_000257"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL1531690.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            complement(24380..25744)
                     /gene="accC"
                     /locus_tag="TV186_000258"
     CDS             complement(24380..25744)
                     /gene="accC"
                     /locus_tag="TV186_000258"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL1531691.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            complement(25778..26200)
                     /gene="fabZ"
                     /locus_tag="TV186_000259"
     CDS             complement(25778..26200)
                     /gene="fabZ"
                     /locus_tag="TV186_000259"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL1531692.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            complement(26197..26670)
                     /locus_tag="TV186_000260"
     CDS             complement(26197..26670)
                     /locus_tag="TV186_000260"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL1531693.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            complement(26672..27904)
                     /gene="fabF"
                     /locus_tag="TV186_000261"
     CDS             complement(26672..27904)
                     /gene="fabF"
                     /locus_tag="TV186_000261"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL1531694.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            complement(27920..28654)
                     /gene="fabG"
                     /locus_tag="TV186_000262"
     CDS             complement(27920..28654)
                     /gene="fabG"
                     /locus_tag="TV186_000262"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL1531695.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            complement(28671..29591)
                     /gene="fabD"
                     /locus_tag="TV186_000263"
     CDS             complement(28671..29591)
                     /gene="fabD"
                     /locus_tag="TV186_000263"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL1531696.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            complement(29604..30590)
                     /gene="fabK"
                     /locus_tag="TV186_000264"
     CDS             complement(29604..30590)
                     /gene="fabK"
                     /locus_tag="TV186_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL1531697.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            complement(30785..31009)
                     /locus_tag="TV186_000265"
     CDS             complement(30785..31009)
                     /locus_tag="TV186_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1531698.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            complement(31067..32041)
                     /locus_tag="TV186_000266"
     CDS             complement(31067..32041)
                     /locus_tag="TV186_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL1531699.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            complement(32041..32475)
                     /locus_tag="TV186_000267"
     CDS             complement(32041..32475)
                     /locus_tag="TV186_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1531700.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            complement(32555..33346)
                     /locus_tag="TV186_000268"
     CDS             complement(32555..33346)
                     /locus_tag="TV186_000268"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL1531701.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            complement(33666..34802)
                     /gene="dnaJ"
                     /locus_tag="TV186_000269"
     CDS             complement(33666..34802)
                     /gene="dnaJ"
                     /locus_tag="TV186_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL1531702.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            complement(34959..36788)
                     /gene="dnaK"
                     /locus_tag="TV186_000270"
     CDS             complement(34959..36788)
                     /gene="dnaK"
                     /locus_tag="TV186_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL1531703.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            complement(37193..37762)
                     /gene="grpE"
                     /locus_tag="TV186_000271"
     CDS             complement(37193..37762)
                     /gene="grpE"
                     /locus_tag="TV186_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL1531704.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(37807..38841)
                     /gene="hrcA"
                     /locus_tag="TV186_000272"
     CDS             complement(37807..38841)
                     /gene="hrcA"
                     /locus_tag="TV186_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL1531705.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            complement(39291..39863)
                     /locus_tag="TV186_000273"
     CDS             complement(39291..39863)
                     /locus_tag="TV186_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1531706.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            complement(39860..40603)
                     /locus_tag="TV186_000274"
     CDS             complement(39860..40603)
                     /locus_tag="TV186_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL1531707.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            complement(40593..41300)
                     /locus_tag="TV186_000275"
     CDS             complement(40593..41300)
                     /locus_tag="TV186_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1531708.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            complement(41375..42712)
                     /locus_tag="TV186_000276"
     CDS             complement(41375..42712)
                     /locus_tag="TV186_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL1531709.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            complement(42727..42993)
                     /locus_tag="TV186_000277"
     CDS             complement(42727..42993)
                     /locus_tag="TV186_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL1531710.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            complement(43257..44372)
                     /locus_tag="TV186_000278"
     CDS             complement(43257..44372)
                     /locus_tag="TV186_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL1531711.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            complement(44569..44808)
                     /locus_tag="TV186_000279"
     CDS             complement(44569..44808)
                     /locus_tag="TV186_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1531712.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            complement(44859..45803)
                     /locus_tag="TV186_000280"
     CDS             complement(44859..45803)
                     /locus_tag="TV186_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL1531713.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            complement(46032..47471)
                     /gene="gatB"
                     /locus_tag="TV186_000281"
     CDS             complement(46032..47471)
                     /gene="gatB"
                     /locus_tag="TV186_000281"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL1531714.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            complement(47471..48937)
                     /gene="gatA"
                     /locus_tag="TV186_000282"
     CDS             complement(47471..48937)
                     /gene="gatA"
                     /locus_tag="TV186_000282"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL1531715.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            complement(48937..49239)
                     /gene="gatC"
                     /locus_tag="TV186_000283"
     CDS             complement(48937..49239)
                     /gene="gatC"
                     /locus_tag="TV186_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL1531716.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            complement(49713..50270)
                     /locus_tag="TV186_000284"
     CDS             complement(49713..50270)
                     /locus_tag="TV186_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL1531717.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            complement(50887..51669)
                     /gene="codY"
                     /locus_tag="TV186_000285"
     CDS             complement(50887..51669)
                     /gene="codY"
                     /locus_tag="TV186_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL1531718.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            complement(51841..53055)
                     /locus_tag="TV186_000286"
     CDS             complement(51841..53055)
                     /locus_tag="TV186_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1531719.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            53342..>53532
                     /locus_tag="TV186_000287"
     CDS             53342..>53532
                     /locus_tag="TV186_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1531720.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQ"
BASE COUNT        15667 a        12575 c        10339 g        14951 t
ORIGIN      
        1 tttttaggca acatcttctt gctcaatttt aggcaggata ccctttttat ttttaagtaa
       61 atcatagata aacaaacgtc ctttttgggt ccaataggta tgcatcttac tccgttcagc
      121 gtctatagtg tgtgtcttgg actgcgtata gcctctgtct gcatattgtt ggtataaaag
      181 ccaagtattt ccttgcctgt attgcacctt taactcatgc aaaagagtgt tcaaccacct
      241 agcactcttt ccataatctt tagcgataac cgtaattgca acaagtgaat cgctttgcaa
      301 aatcaagtca taataagtag ctttgggttt catctcacta ataatttgat ttttctgtgc
      361 tacttcttcc tgagcttgta agcgtaactg ccgttcttct ttcaaacgct ggaaagctgc
      421 gatggccata tctgggttgt ctaataagtc accgaccgca tacatgccat gctttctgac
      481 agcaggtaga acttctgatg tcacccagcg cttaaactct ttagcttgcg gaagcttgct
      541 tgacaagata agcgagtaaa gaccagattc attgatgacc actggtgttt gttctctgcc
      601 catggagtca cgaatcgtta ccccatctgt tttgtcatct tcatcaacat gatccaacaa
      661 tgcttttctt gaatttgaat atccaagaat actagccaca tctttaccta caaaataagg
      721 ttcaccatta attgttactg ctcggacttc ttgtccttta aagttaaaaa tttcgttcat
      781 gttaatcctc caaaagtttt tcaagcggaa ctctaagata atccgcaact gatttaagcg
      841 ttgttactga tggaatactt ttattccact tacctattga tccattactt aaagatagat
      901 ctctttcaat acgataaatt gaaatgtttt tctctgaagc aatggctttg attttgccac
      961 aaatcatttt attcccccaa agatgtccag ctctcatcaa ttcgcagaac gtcacatacc
     1021 ttattcttta atcggtcact tcctttgccg tatttcaaca gttcggtgat tgttggggac
     1081 ttcaccccaa cagcgcgggc gagttgaaca tttttccagc caaactcttc cattttttgt
     1141 tcgactaaat ctagccaaag ttcttgctgt ttcgacatag ctttcctcct ttctcaaata
     1201 tttgctaaaa agttagctaa gttcttgact ttttttcgcg catgcgctaa aattaaccca
     1261 taagaaaaac acttgataaa acctagttat gtcaataatt ctgctcgcca aagctattat
     1321 tttttttact aggtaaatag cttgtgtttt gctaactcat taccttacaa aaactatttt
     1381 agcgtatacg caaaaataag tcaactattt tttgccaatt cactaaatat tttttgccaa
     1441 tctcttagaa aggttgataa aacaatgttt ttaacatttg aaaaaattaa agaactcgct
     1501 aaaaagcaag gactttcttt aaatgatcta gaagaaaagc tgggcgttgg caaaaactca
     1561 ctctatggtc tgaaaagaaa ccaaccgtcc gcggagcgtc tacaacaaat cgccgactac
     1621 ttccacgtct caacggatta ccttctaggc cgcacgaata atccgaacat agccgacgat
     1681 aaaaaagaaa cttttagtgc caggggtcga gctattgccc gaaaatacga tagcgcaagc
     1741 cctaaaaagc agaaatatta cgatagaatg attgctgcta tgtttgaaga cgatgaggag
     1801 gacgattaat tgaaaatccc ttcctcgcct agatataaat ttgcaaccca catggctcta
     1861 gagactttca catattttaa tgtgttaagt tttccaattg atgtcaaagc gttgataaaa
     1921 tcagaaggga ttagactaaa aaaatactcc accatagcca aaagagtagg gatctctctt
     1981 gacgaggttt gtaaagagta ccaaactgac ttagcttata tttttaggca aagttctgga
     2041 gaatacgcta ttgcatacaa cgacactaaa cctgagtatg taataagatt tagtctagct
     2101 cacgaattag gccactatgc attgatgcac ttagaagatt tcgatgagac aattctcaga
     2161 tacagaggaa acgggctagt cgagaaaaaa tatcaagtgc tagaaaaaga agctaactgt
     2221 tttgcaagaa atctagtttc tcctgcacct gtcgctgatg tcatacctca agaaatgtat
     2281 caattatact ttggaatagg ctatggggca gaacaaacta ggattaatct gctacgttct
     2341 gataaatact atacaaaatt attaaatagt gacattggca aaaaacactt ttctcgtctt
     2401 aggcgcagaa tttcgcatac acacaagtgc ctgaactgca aggcttgcgt tgttagaaaa
     2461 aagattaatt tctgcccaat ttgccaatct gacgaactga aaaaattaga ccttagagag
     2521 ttaatggatc tagaaaggca aggtaaaatt atgaaatatt catctataga actaggcgaa
     2581 aataaatttc ctataaggtg cccaagatgt gagaacgaag atattaactc tagcgaaaaa
     2641 ttctgcccga tctgttgtac atatctaaaa aatatctgca taggaaaagg accattttat
     2701 gaagatgcag atgagctcta tccatccttt cctattgata gagaaaataa cggatgtggt
     2761 aaggaactta tcggttcggc aagatactgc tcagattgtg gcgggataag ttcatatttt
     2821 aatcagggat tactaagctt ctgggtaaac gagaaagaaa agtatgacat tttaggtgaa
     2881 atgccttttt aaacaaaaaa agaatttagg agataaaaat gaaaaggata atctatctgt
     2941 ttatgttgtt actctcagta acttatctag cagcatgctc taacagttcc acaaaagggg
     3001 gagattttaa aacgtatata aaaaatactg atttcaaaag catagaacac gattcaatca
     3061 ataaccttta catcgtcagt caggatctca atactattat aagtgatgaa aatgctataa
     3121 acagtttcaa tgattcgata tacgacgtat tacagctagg gtttaaaaca gataaagaca
     3181 tcatttttag gggctgggat ggtaatcttg cgggttctct cgtctacttt gacaaggata
     3241 cttttaacca aaaatggggt gtatcagact ctaataagat ttacaataaa tctagcggat
     3301 ggcaaactat cagtaaattt aatcagtatt tagattcaaa aaacagtgcc aagactccag
     3361 aaatagaaga gagactcttt gagctggcta tgtacagcaa aaaataaaaa aagccccacg
     3421 ctcaaatttt tgtcgaggag agcgtaaggc caaaccgtat aagaaaaaaa gcattaaatg
     3481 gctcgttttc ttgtacccat tttaacagaa aaatgaggtg aaaacaatgg cattttatcg
     3541 aaaattagat tccgggtggg agtatcgcat cacctatcgt gacagtcaag gtaaaaaaag
     3601 agaaaaatca aaacgtggat ttaaaacaaa aacacttgca aaagttgccg cccagcaagc
     3661 agaaactgat ttaaacacgc tgacggcaga ccttttagat attactgttt tagactacaa
     3721 caagcgttgg gcagacatat ataaaagacc tcacattacc gcaaagacgt ggcagacata
     3781 tactaagaac tttaagcaca tcgaacatta tttcgggact cggaagctca agagtatcac
     3841 acacaccttt tatcagcaag tccttaatga ctttggcgaa aaagtagccc aacaaactct
     3901 ggataaattt cattatcaaa tcaagggtgc ttgtaaaatg gccattcgtg acggcattat
     3961 tagggataat tttgccgatg aagccatcgt taggtcgcaa aaacccgcca aagaagaatc
     4021 ggaaaaattt atggaggaat ctgaatacct tgcttttatc aagactgcta aggaaaaaat
     4081 caagtaccca tcatacctta cgacatatat catagctata acaggtttac gatttgcaga
     4141 agctcaaggg ttgacatgga aagatattga ttttgacaat ggctatgtcg atgttaataa
     4201 aacttttgat tactcgattt ctcaaaattt caggcctaca aaaaacgagc aatccatcag
     4261 gaaggtccct attgataaca atagtgtgga attattaaaa tattttaaag ataatcatta
     4321 tcaagataat aaactaagtc gtatctgttt cggagcgtca aacaatgcaa cgaacaaagt
     4381 tataaaaaga gtgaccggca gaaatctaac caatcactcg ctaagacata cttacgcttc
     4441 ttatttgata gcgcagggcg ttgatctaat atcagtatcc aagctgctgg gtcacgaaaa
     4501 cctcaacatc acactcaagg tttacgctca tcagatagaa agtttaaaag aaaaaaatga
     4561 ccatcaggtc aaaaacattt ttcaaaatct caaatttgac gggtgaaaaa cgggcgaaga
     4621 ccccgaaacc cttgatatac caagaggata aaaggagagg aggggattcg aacccccgag
     4681 ccccgttaag gactacacgc tttccaagcg tgcgcactcg gccactatgc gacctctcca
     4741 agtaaaaggc tgatcaactc aacctcagta gtgtatcata tttttgtcaa aatagctact
     4801 agaatgttgc ttctaggcgg taaataatct gtcccttttt agcaaatcta gcctcatact
     4861 cagtcatcac atttccttga taatcactag catgtaaatc cagccagacc tgcttgaggg
     4921 tcataccgta ctgtgaaaag ctcgctaggc tatactcaaa taagccacga ttatctgttt
     4981 taaaatgaat ttcaccattt tccggcaaaa tctgcttata agtgtctaaa aaggatttgt
     5041 aggttagtcg acgcttttca tgcctgcttt tgggccaagg atctgaaaaa ttcaaataca
     5101 tcatatcaac ctcaccggca tcgaaataat tggtcaggct tgacccatca acccgcaaga
     5161 gcctaacatt aggagcctga gaggctagga ccttatctaa agcatagctt agcactgata
     5221 gctgaatgtc aatgccaata tagttgatct ctgggttttt caacgccata cctgtgataa
     5281 aggctccctt gcctgagcca acctcaatat ggatcggatg atcattacca aagacctcac
     5341 accagcgccc cttagcagcc tccggctcta aaatgacata gtgaggattg ttttccaagt
     5401 gctcctgcgc accctttcgt tttctaactc gcattatttc tttctaaaca tttctctaaa
     5461 ttttctaaga gcgtaaatct cttgattgac atgctccata tctctcttat caaagcacct
     5521 taaaatctga gttagataag agaattgagc ataccaaata atcttttgca tgaccttatc
     5581 attattttta tagccataat aggatagcca gtctgcccat cgcgaccgag gaatatagtg
     5641 gcttagcaaa taagccacat catacattcg atctgttagg cgcacacaat cccagtccac
     5701 caaaaaaatc atgccactgg tggtaatcac ccagttgcta tgcttgatat caccatgtac
     5761 aatcgtggcc acctcagagc gaaattcagg taggctgcgc tttagctcct tgacgatagc
     5821 ctgtaaataa gaattctgtt gaatttgcaa aggtgcattt tgctcaaagt ctactaaaag
     5881 gtcataagga ttttcaattt tatagttgag ctgaagcaat tgattaacca actgcttgga
     5941 cttgtggagg cgcagcagaa tatggacgat ttgcttactg ttcatatcct ctctagtcag
     6001 agtacgacca ttgagccact cttgagcact catcatatcg ccattcccca tacgctttgc
     6061 ccaaagcaat tgtggggcaa tctgttcctt tgctaaggca ggtaggattg gtgttgtatt
     6121 aagcttgata aagacgcttt cgccatttgg ataggtccct ttgtaggctt tgccactttt
     6181 tccgcgcaag ggagtcaata caagatcctg ttcggttgtt gtcaccttat cccctccttt
     6241 tctatcttct gtaaccagtt atccctattt tacttgtttt aaaggactta gtcaatcatc
     6301 ttctttaact tgtacggtaa gtaaagaaga tttaataatc ccatcgccac aatcaacaca
     6361 agagcatttt gccaagaacg gcagagcaca agattgacga taagcatcaa accacttaat
     6421 tgcctcaaca aagaaagtag attcctttgc ttatgctgtg gtttagtcgg gtaaagccca
     6481 ctcatataat ggtaatcata atgatgataa agtgataata actgaaaaag acttagataa
     6541 tgaaagacca aggccaagcc tactgctaaa taagggttgg aaataaaggc aagtgacaag
     6601 caactaagca acaacagacg taaccataac cctagataat cagagctgcg taaaaatgct
     6661 cttaaatata ggtttgtcca aaccttttta ctatctgcct tgataagctt aagtatagga
     6721 ttcaagtaag gcctttcctt aaccttggtt gagattcctt taacatttgt aaacaaagca
     6781 taaaacttta aaatggcctg ctggcgatct gcctcaaaag caatcgcttt ttcccaatca
     6841 agccccttgg agctcaaaaa gcttgccacc ttacgcttta acagtaagcg cttagccagc
     6901 accaaaacac caagcaatag cacaaaggca agcaaggaaa caccaagcct ttgaaacaaa
     6961 ggaaataaag gtaacagcaa gaccgtttga aggctagacc aaagaataaa ggacaagcgc
     7021 tctgctgacc tgatatgggc aataacctct gcctccttgg tcagcaaaaa atgctgatca
     7081 gccttttcaa gataggtagc aactgacccc agattaagca aaaacaagac agcaatcaac
     7141 aaacctagct gaatcggtag aggattagca ggaaaatgct tgagtagttg actgtactga
     7201 aaaagaataa agcccaaaag aaacagcaag acaagaacaa aatgatcatt aaagacataa
     7261 ggcagatact tggtatgctt gtgctgaaac tcctgacgac gcttacgaaa taatgccttc
     7321 atagcttacc cctcttttgt cagcgctagg taaatgtcat taagactagc tgaagcatct
     7381 ccaaagactg cctgcaaatc cgccagagtc ccttgtgcac gcacctgtcc ctgatgcaat
     7441 atcacaaaac ggtcacacat tttttctgcc gaatccagca catgggtact cattagaatt
     7501 gacttgccct ttgccttttc aacctctaaa gccttaatca aatcagcaat tgctaagggg
     7561 tcaagcccca aaaagggctc atcaagaata aaaagactag ggtcaatgac aaaagcgcaa
     7621 ataatcataa ccttttgctt cattccctta gaaaaatgca ccggaaacca atccagctta
     7681 tccgtcaaac gaaacagctc taagaagggc tcagctcgct tatgtgccag ctccacatca
     7741 atatcatagg ccatagctac cgtattgata tgctctgcta aggtcagctc ctcatacagg
     7801 cttggtgttt ctgggataaa gccaattttc ttgcgataat cagcttcatg ctccgccaag
     7861 gttaagccat caatggaaat ccttccctta tatggcttta aaaacccaat aatttcatta
     7921 atcgttgttg acttaccagc accatttaga ccaataagcc ctactagctc tccatttccg
     7981 acagaaaagc taatatcctt caaaactgga atattaaggt agcctccagt gacattctca
     8041 atgtttaaca tatcatttct ttctaatatc taatctattg tagctttgca tactagcttc
     8101 cctagatgac aggttattag cctagacaga taggacttac taggcaatgc tttgtcatca
     8161 tcagcctatc cagcgctttg aagcactgat aagaccaatt agcttgaccc tacttaagaa
     8221 agctggggca gctaatacta agggtacact tatattagct attataacaa atttctgcac
     8281 agagcgttaa ctgttttgat caatgctccc atcagctaaa aacgctgagt gaatctgaag
     8341 tctattttaa gatcatcaag aaaaaggcct agctataaaa acagaggcta tattagcttg
     8401 atctatcagt cctaaccatc tatcacatca tattcgaatg acctggtgat cctaaatagc
     8461 agctcatcta aggcgtcatc taaaaaatca tgataatatt atcttattgt attgaatttt
     8521 taataatata atgttatcgt taacatgtaa ataagtgttg cgtctttaat gacaaaggag
     8581 gtatgttatg aatttgtcac gctttttaac atttggtttg gtatcacttt cagcactttc
     8641 aatttcaggc ctagtccaaa cagaggctaa ggctaacgaa tggcagacta tctttgaaaa
     8701 gccacaggag gtggttatca cagatggctg gcaaactatc tctgaaaagc ctcaggaagt
     8761 aagcacggct aacgaatggc aggtcagctc tgaagaagct caagagtctg ttcctgataa
     8821 attctcacaa aacgaagacc ctagcctatg ggctgttcct gataaattct cacaaaacga
     8881 ggaccctagc ctatgggccg ttcctgataa attctcacaa aacgaggacc ctagcctatg
     8941 ggccgttcct gataaattct cacaaaatga ggaccctagc ctatgggctg ttcctgataa
     9001 attctcgcaa aacgaggacc ctagcctgta gtaaagccat ccgcactcga ttgaagataa
     9061 ggcctatgtt gctgacgctt caatcttttt ttgttctaaa agctttctca gccttaactg
     9121 tcaagaagtt ccagcacctc atactctctg aaactcttgt ccttacaaat attgtgccat
     9181 gtcactaccg tacgatagtg cgcaaatgca cacctttgac ggacctagct tgcagcaagt
     9241 agcaggctta gttatgtgct taaccataat tgcttagtcc attatcatga ttcaaaaggc
     9301 tttgctagtc atgtggtcga taaccattag caccagctat aaacaattgc aatatagacc
     9361 agtacatgct aagataacta tagtatgaga tagctatggt cactgagcaa ctactgattt
     9421 cttattctaa aattattcaa ctactgattt gagccattgc tacgcagacg aaaggattat
     9481 cacatggaaa attgtatctt ttgcagcatt attagcggtg agattccctc ctccaaggtt
     9541 tatgaggatg agcaggtact cgcttttttg gatatttcgc aaacaacagc gggtcatacc
     9601 ctcttgattc ctaaaaagca tgtccgaaat atcctagcaa tggacgccga gacagctagc
     9661 cagacctttg aacgattacc taaaatcgct cgcgccattc aaaaagcaac aggtgctact
     9721 gcaatgaaca ttattaataa taatgaagag ctagctggtc agactgtttt tcacgcgcat
     9781 gtgcacctcg ttcctcgcta cagccaagaa gacgggatcg ctattcagta tacaacacat
     9841 gagcctgact tcccagccct agcagccttg gcacaacaaa ttagtcagga gattagccaa
     9901 tgactctaaa aacaatgacc acaattggtc tcacatccgt tttagcctac caagtgtatc
     9961 gtaaacgtca tcaaatcaaa gaaactctag tagccatgca aacctctaag aaggctatcc
    10021 aggccgatgt tgataggatt aaggcaaatc tcgccatcat tcaaaaggag gctcgaacgc
    10081 ttcaagcagc aggaacagaa ttagcctaca aatggcaggc ctttaaccaa gaagctcagg
    10141 cccatctgac tgaaatccaa caacgtatga gcaagtacca gcaggaaacc ccataagcct
    10201 aagcagacta ccaagcctca aggtgacaaa aaagggctct atcgtttctg tagtggacaa
    10261 gtccgctata gggattatgg gctctttttg tatgtacaaa aaagacgaag aaatcactca
    10321 caggatcaag ccttgatgag atttcttcgt ttttttggct gtaccctaag gcgctgctgg
    10381 cgtaccagtg gttgcaccac ttgattgctg ctctgctggt gagtctgctt gagggctagg
    10441 agtcacatta gctgctcctg actcttgtgt accagctgtt gtgtcctgat agctgctgct
    10501 agaggacgtc tctgaggaat aggttgagta ctgggtagat gagtctgtat aggccggtag
    10561 gctacctgaa ttgtaataat agctgctatc ctgagtagac tgagttttta acgagccata
    10621 aaggttttcg taaactgtgg cagtcgtttt tagctgacta agcttttcaa ggcctaattc
    10681 agcacgaatg cgattttgga tttctaaaag atgatctgag gtcacaattt gataggagcc
    10741 gccatctgac aaggtcgctc cctcaccctt tagctgatag gttttgatat ttttaagggc
    10801 gtctgtatag cctaaaagat taggaatggt tcgtgatgat atttcaatgt tggtttgcat
    10861 attaccacta acagctgaca agatctttcg gtaggagctg atactgttaa gggcaagaat
    10921 ctttttcagc accttttgaa taacctcgcg ctgacgcttc tgccgaccgt agtctccctc
    10981 tggatcatca tagcgcattc gagcatagac caaggcctgc tctccattta tcttgtgagt
    11041 tcctggtgca acggtagcct gatactcagg ctcattatct gcaatagaga taggaaagtc
    11101 aaattcattg gtaacagtaa tgccaccaac agcattaacc aaatcaatga gcccttgcat
    11161 gttaatctga acgtatttgt caatcgtgat attcagcaag tcctgaacgg tcatgatagc
    11221 catttgggca ccaccagctg cataagcagc attcagctta gcttctgctc cattcatctc
    11281 attatcattt ggacctgaca aagtgatgag aatgtctctt tctaagcttg tcatggttgt
    11341 ctttttggtc ttagggttaa tcgtaaccag aatcatagaa tcactatttc cttgccaggt
    11401 agaggttctg tgagacgatc ctgtgtcaac tcccatcaat agaattgaaa agggctctgt
    11461 ctgttgaatg gcatcacttt ttttggagga cgttgcaaaa tccttaaagg tctttgacaa
    11521 ttctccagtt gaaaaggtat aggcattggt taggtaaact cccatagccc ccaaggtcaa
    11581 cagcacaata gctgtcagca ttaaaaagat tttttttcca attttcatct attcacgttc
    11641 cagatattta cgcataaggt aaacatcctg atagtctcca tttcttgatt tgacgtcctt
    11701 tcttttgacg ccctctattt taaagccata tttctcataa atatgatagg cacaagtatt
    11761 tcgagcctga acctccagct ccaaagcaca aagctgcttt gtttctctgg cccaatcaag
    11821 ggtagtctcc atcaaaagct gtcctaggcc atgattgcgg tagggtttca agaccagcat
    11881 aaagcaatcg ccaacatagc tagtctcacg atatgctttg ccagctatat ttagcagacc
    11941 agctaatata tctcccacct ttagcaaaag gcaaatatct gtcaaagact cctgactagc
    12001 ctctagaaaa cactcaagca cctctacggt agcagctatg acgtcctcag tccctgtgat
    12061 aaaatctgtc tcatcagcag cttctttaat tagagtgatc aaagctgacg catctgaggc
    12121 cttggcctct tcgattgtca ccacctgctc agacatgctt aagctcctca agaagtgcct
    12181 ctgatcgatg accatgtgct agataatcaa cctgccggcc tgtttctgtt tttgttatta
    12241 aaatttcaag gtagtcatgc agggttccct tggctaaaag ctcgccccac tcaatcacag
    12301 taaccccacc accaaagata aaatcatcta aatcaataga gtccggatca tcaccaatcc
    12361 gataaacatc taaatgatac aagggtagtc ttccctcata ttctcgagcg atagtatagg
    12421 ttgggctttt aatcatctga tcaatcccca aacccttagc aacccccttg gtcagcgttg
    12481 ttttaccagc acctaagtca ccagtcaaga caagcacatc tcctgccttt agctgtctac
    12541 caatgccttg cccgtaagcg attaattcat tctcattttt gctataaaac ataaggctat
    12601 tataacagaa aaaaaacggt cttccaagcc taagccagcc tgtcagcaaa atattctagg
    12661 ctcgtcagtc ctcatataat gtcgtcaaag ctcaatcagc tttaacatct cataaatcaa
    12721 aagagccagc agcaaatcac atggacctaa catcatggca ttctgctgtg atagccaggg
    12781 ctgaatgctc tagaaatcaa cccgcagctc taaaacctta agacttagcc taaatatagg
    12841 actaggaaaa ggtggcaatg cctatgagct tagaaagtcc atagtcccag tccaaacggt
    12901 aatccctgtc tttattgtcc cagcaaaaaa gaggcaccta agtacctcat tagtcgttta
    12961 caataacgct aaaatgataa aattcaaaac aaataagaag gttgctcccc aaagaatcgg
    13021 gtgaatctcc ttggttttgc ccttcacaag cttcaccaag caatagaaaa taaaggagcc
    13081 agccacaccg tatgaaatag agtagcaaag tgccataaag aaagcagcaa agaaggacgg
    13141 tagggcaacg tcaaagtcgc tccaatcaac atcaaggaag gacgatacca tcataacccc
    13201 gacaatgatt aaggctggtg cagtcgcagc ggctggaaca attcccacga tcggcagcag
    13261 taaaacagat aagacaaagc agacagcagt tgatacagct gttagacctg tacgtcctcc
    13321 ctctgcaata ccagcagcag actcaacgta ggttgtggta tttgaggtgc caaataaagc
    13381 tccgattgaa gtaccaatag cgtcagcaaa gagcgcacgg tccatttttg agctaaagcc
    13441 agagctgttt tccaaagctc tctcatcctc ctcagagaaa atccctgttc gacgaccagt
    13501 cccaacaaaa gttccaatcg tatcaaaggt atcagataga ctaaaggcaa agatcgtcat
    13561 taaaacaagc ggcaagcgac ttgaatcact aaacagtgac gccatgccac caaaggcagc
    13621 caagaatgtt gtccctaatt cagcaaaggc tgagctgatg tgattgtctg caaaattaac
    13681 agcagaaaga tcaaccactc caataggaat accggctaaa gttgtaactg taataccaat
    13741 taggatggct ccacgaacgt tcttaagcac aagcactgct gttagcagca gaccaaaaac
    13801 tgctagcaaa acactcggat cggtgaaggt tgaaatagct ggaaccacac caccattagc
    13861 attaacagag aagacgccat tagcaaatgt ttcagcagtt gccttagctg gctcaacacc
    13921 atttacagta acaatctcag cagatgatag cgaaaaggtg atcaggttag catttttaaa
    13981 acctagataa gcaacaaaga ctccaatacc tccgccaata gcatgctgca ggcttactgg
    14041 aatagccttg ataatgctct tgcgaagctt tgtgacagtg ataaagatat taaacagacc
    14101 acaaagaaag acaatagcca aggcctcctg ccaagaaaat cctaagctaa aaacaacagt
    14161 gtaagtaaag aaagcattaa gtcccatacc aggagccaat gcgtaaggca cattagcaaa
    14221 caaacccatg atcaaggtag agatagcagc tgcgatgatg gtcgctaaaa acaccgcttg
    14281 cgacggcata cccgctgcac tcaaaatact tgggttaaca aataagatat atgacatcgc
    14341 aaaaaaagtc gtcacaccag ccatcagctc tgttgaaacc gtcgtgccat tttcttttaa
    14401 cttaaaaaac ttttccattt gaatggagtc tccttattga taggcaaaat caaaaaagcc
    14461 cttatctcat cagataagct ttttctctta aaaccaaatg attattatcg tttttacgaa
    14521 cgatatattc atcgtaacat tttatcgttc tattttcaat agcttttttc gtttatttgc
    14581 catgatcgtt caaaatttaa cagccttttt ttctattaac cgtccaagca gcaattttct
    14641 cttccactga tcctaaaatt tgttataatc tagtgtatga ctaaaaaact aattgctatt
    14701 gatttagacg ggactttatt gcatcacgac aataccatct ctacctatac tcaaaaaacc
    14761 attaaggccg tccaagctaa gggacatgag gtcatcatct cgacaggacg tccttatcgt
    14821 atggctattg actactacct tcagctagag ctaaagacac ctatgattag ctttaatggc
    14881 tctttgaccc acctacctga gcaaagatgg aaatacgagc ataatgtgac tcttgataag
    14941 gcataccttc tcaaactcct agcagtgcag gaggacttcc agatggactt tattgctagt
    15001 gagtaccgaa aagccttcta cattaccatg aataggcctg agagcattga ccccaacctt
    15061 tttggtttga ggccatcaca ccagatatgg ctttacagat cgacaaaatc acgcaggatc
    15121 caaatgctct tctcatgcaa acgcatcatg aggataagta tgccctagcc aaggccatgc
    15181 gcgccttctt caaggacgaa attgaggtgg actcttgggg tggtccctta aatatccttg
    15241 agatgtcccc caaaaacatt aataaggcct ataccttaaa atacctgctt agcatttaca
    15301 acaaggagcc taaggattta atcgcctttg gtgatgagca taacgacaca gaaatgctgg
    15361 cctttgccgg aaccggctat gccatgaaaa atgccagccc tgtgctgctg ccctttgccg
    15421 accagcagct agcttactct aacgaagagg acggggtcgc cagaaaacta gaagagcttt
    15481 tcttgtgaaa gcaaacgaaa ccattgtttt tcagaaaacg atggttttct taatgccgtt
    15541 tccgtcaatt gatgaaagaa tttctaatat tttcgttatt tttcagcata ttttcttttt
    15601 tatgcggcat aaaaatccct ttattatcaa tattctactt attcggcagc gcattatgaa
    15661 aattttttca tatttcgtaa gatttttccg aaagggcttg atttttaagt gaaaacgttt
    15721 taaaatagag acgttcttga atttcgttca agtgaaaaag aattgccaaa tgctatttgg
    15781 aaggagatta ttcttcttca tttcaacgaa aaatatttta ataaggagga agaacaagaa
    15841 tgggtatcgg tattattatt gccagccatg gtaaatttgc tgaaggtatt catcaatctg
    15901 gttctatgat ttttggtgaa caagagaaag ttcaagttgt gactttcatg ccaaatgaag
    15961 gaccagatga cttgtatgga cacttcaaca atgctatcgc acaatttgat gctgatgatg
    16021 aaatccttgt actagctgac ctttggagtg gttctccatt taatcaggct agtcgtgtgg
    16081 caggagaaaa tcctgatcgc aaaatggcta tcatcactgg tctaaatttg ccaatgctta
    16141 ttcaagccta tactgagcgt ttgatggacg ccaatgcagg tgttgaacaa gtagccgcaa
    16201 acatcattaa agaatctaag gacggtatta aagcccttcc tgaagagctc aatccagttg
    16261 aggaggcttc tacagctaat ggtggtggtc aagcgcttca aggagctatt cctaagggaa
    16321 ctgtcattgg agatggtaag ctaaaaatca accttgctcg tattgacact cgtcttcttc
    16381 atggtcaggt agcaactgca tggacaccag cttctaaggc tgatcgtatt attgtagcgt
    16441 cagattctgt ggctaaggac gagcttcgta agcaattgat caagcaggcg gctcctggtg
    16501 gggttaaggc taatgttgtt ccgatcaata aattgattga ggcttctaag gacccacgct
    16561 ttggcaacac tcacgctctt atcctgtttg aaactgttca ggacgccctt cgtgcgattg
    16621 aaggcggcgt tgagatcaaa gagctgaacg ttggatcaat agcgcattca acaggtaaaa
    16681 caatggttaa caacgtattg tctatggaca aggatgacgt tgctgccttt gaaaaattac
    16741 gtgatctagg tgtttcattt gacgttcgta aggtgccaaa tgattctaag aaaaacctat
    16801 ttgagcttat ccaaaaagca aatgtgcaat aagcaattta gaaataagag gtaggcttgt
    16861 ttaacgcaac aagctgtctg cctcatctac aatgctgcga tgatatgata agcctgatga
    16921 ttgcttctag acaaatcatc atcacttaat aacgctttat attgtccatt gacaattgac
    16981 tcatatacga aaggataaca aaatgtcaga tatttcatta atttctgcaa tcttggtcgt
    17041 tatcgttgcc ttctttgccg gtcttgaagg tatcttggac caatttcaaa tgcaccaacc
    17101 acttgttgcg tgtaccttaa tcggacttgt gactggtcac cttgaagcag gtgttatgct
    17161 tggtggtact cttcaaatgc ttgcacttgg ttgggcaaac attggtgctg ctgtagctcc
    17221 tgacgctgct cttgcatctg ttgcagcggc tattatcatg gttaagggtg gcgactttac
    17281 tcaaaaaggg attacctttg catactcaac agctattcct cttgcggttg caggtctttt
    17341 ccttactatg attgttcgta ccatttcaac tgtacttgtt cacgctgggg acaaggctgc
    17401 tttagagggt aacttctctg ctatcgagcg cttccacttt gctgcacttc ttcttcaagg
    17461 cttgcgtatt gctgtaccag ctgcacttct tgttgctgtg ccaactgagg ccgttcaaag
    17521 tgtcttgaag gctatgccag cttggttgaa tgaaggtatg caaatcggtg gtgctatggt
    17581 tgttgccgta ggttacgctc ttgttatcaa catgatggct acacgtgagg tatggccatt
    17641 cttcgcactt ggttttgccc ttgcagctgt gacccaatta acacttatcg ctatgggtgt
    17701 tatcggtgtg gctattgcct ttatctacct taacctttca aaacaaggtg gtaacggtgg
    17761 aggtcgagca ggctctgctg acccaatcgg cgatatccta gaagactact agaaaggggt
    17821 aagattaatg actgaacaaa ttaaattaac aaaagctgac cgtaaacgtg tttggtggcg
    17881 ttcacaattc cttcaagggt cttggaacta tgagcgtatg caaaacatgg gttgggctta
    17941 tgcacttatc ccagcactta aaaagcttta cacaactaaa gaagatcgtg ctgctgcact
    18001 tgagcgtcat atggaattct ttaacactca cccatatgtg gctgctccta tcatcggggt
    18061 aacgcttgcc cttgaagaag aacgtgccaa cggtactgct attgacaacg ctgctatcca
    18121 aggggttaag atcggtatga tgggacctct tgcaggtatc ggtgatcctg tcttctggtt
    18181 tacagtgcgt cctatccttg gtgctcttgg tgcttctctt gcacaaactg gtaaccttgt
    18241 cggtccactc cttttcttct ttggctggaa cattatccgt atggccttct tgtggtacac
    18301 tcaagaattt ggctacaagg ctggatctga aatcaccaaa gacatgtcag gtggtatcct
    18361 acaagacatc actaagggag cttctatcct tggtatgttt atccttgctg tccttgtaca
    18421 acgctgggta tctatcaact ttaccatcaa ccttccaggc aagcagcttt ctgaaggtgc
    18481 ctatgttgtc ttccctgagg gagccgttaa aggtgctgag ctaaaaagta ttcttggaca
    18541 agctatgggt ggcatgagcc ttgataaagt tcaatcacaa acccttcaag ggcaattaga
    18601 ctcattgatc ccaggacttg ctggattact acttaccttc ctttgcatgt ggttattgaa
    18661 gaaaaaagta tcaccaatcg caatcatcat tgccttgttt gcatttggta tcatcgcaca
    18721 ccttcttcac atcatgtaat aaaaattaag gaattggggg cttcccagtt ccttaatttt
    18781 tggctgtcta gagccttagc aaaggccagt attcagcctg ctacaagcta tatttttatg
    18841 ttataataga caaaaacact aaaggactta ttatggcaca atctttaaat caaagggtga
    18901 tccttcagac aacagccgtc tcctatcttg gaatcggagg aaaggttggg aaaatcttac
    18961 ttggagataa ggctttggaa ttttacaatg ataaaaacgt tgaggacttc attcaaattc
    19021 cctggacggc cattaaccaa atcggtgcca atgtttctgg caaaaaggtc agtcgtcact
    19081 ttgaaatctt taccgatcaa ggcaaatttc tctttgcttc aaaggattca ggaaaaatct
    19141 tgaaggttgc tagagaaaca attggcaatg acaaggtcat caagctacca accttggtcc
    19201 agaccataat agcaaagcta tttcatcatc aaaaaaagga taagaaatct cattgatggg
    19261 cctgccttaa ttcaatatta cggtcataga ccagcatgat aatactctta gacatagcac
    19321 catagcaata tgtctaagag tttttttcgt tgctaacaaa aaagcttgaa aaacaagctt
    19381 acagaatgta gacaaaccct atcagcgata gaaaaattga aaatttagaa attgactatc
    19441 atataatgaa aactctggaa aatgctgata ttacagtatt tttcagaatt cttttgtttt
    19501 tttgattaaa agaaaaagct tgaaaaacaa gcttaagtga atcctttcta caatctaaat
    19561 ctaaccttat tcctcatcaa tctgcaaagg ggattttctt gtccacccat ttcaacaaat
    19621 tttgaaagcc tagtttttta aaaagcatca gccttgcctg ttcaaccaga aaggacaaaa
    19681 aataaatcac aatgccgacg ccaaatatca gtagtgggta taaaaggata ggagcattga
    19741 caaagggctc tgcaaaatcg cgaataataa atttgaccag caaggggtgt aagtgcacca
    19801 gataaatacc tagagtcgtt ggagacacga tcacaataaa gcgtagcagc agtgtttctg
    19861 atgtcagctt cagcttagca aaaagaataa ataaggcaat agctcccaag gtcaggctag
    19921 gtgatacata ccagtaccaa atatttccca ccataaattt catgatatag gtaactacca
    19981 aagatcccat ataaaccgca ataagaagct tatgactaaa cctacttagc tctatcctcc
    20041 ttagataggc tccgataatg tagagaataa tcagccaagt catttcaaag cccttgctta
    20101 aggaaaattc atcgacctgc tggttcatca gagctgggat caacgaaaaa atagcaaaaa
    20161 ccagcagtac caatcggcct agctgcttat tggataaggt attgaggcca ccattgatca
    20221 taggcataaa aatcagtaac ccaaagtagg cggtgatata ccaataattg ccactcacta
    20281 tgggaaagag ggcctgacgc caattctcta agctaactgg aaagccaaat agagcaaaca
    20341 aaagggtcat cagaaagcta taaaagaaga cttgtaccca aatattaacg attttggaat
    20401 atttataggg cgacttaatg cccacatagc cactaatcaa cgcatagcaa ttgaccgccc
    20461 cataaacaag aacctgaatc atccaggtaa caataaaata agaatctgcc tcaccttcga
    20521 cagttgaccg caagccgccc tttcccaaaa catgtgtgat cacaatcata aacatggaaa
    20581 tgattcgcaa taaatctaaa ccgtaatggc ggttcttatc taatgtcatt acatttttac
    20641 gcataatatt agtttaccac aatttttaat atttaacgat ttgattttgt ctgacaacga
    20701 gattttttgt gcctctgacc taagctctac ttgtcatcag ccttttgtat tactgacgct
    20761 ccgtgacaga cacatgaaaa agttttagca agaaaagaaa gctttctgta tttcaaggat
    20821 atgtcttgtt ttttatagac tttactatag gaaaaacatt gaaagtgtct actctaattc
    20881 caaaataact agttcgcgcg tttgatgtag ctgacactca tttgggagtt tactttttct
    20941 ccttttttgt tataataggt ctagcggata agtagtctgg ctctgtcttt cagagagtct
    21001 gtggttgctg aaaacagata gaggagtcat acgaaattct accgtctacc aattaaatat
    21061 gaattaagtg cacagattgt gaagctggat ggaaccgcgc ttaggcgctc cagtgtattc
    21121 ataggctgtg cttttttatc tcgtcagaaa taaaaaagcg atcagctagc tttgctcatg
    21181 ctattttata actgactatc ttatcaccag ctcaaaggag atttatttat gctagatctt
    21241 aagcgtattc gtactgattt tgatactgtt gctgctaagc tcaaaacacg tggtgtgtca
    21301 gaagctatcc taacctctct aaaagcctta gatgaacagc ggcgcaccct gcttgttcaa
    21361 acagaagagc taaaagccca gcgtaatatc gcctctgctg ctatcgctca agccaaacgc
    21421 caaaaggaag acgccagcca acagattgct gacatgcagc agctagctgc taacatcaag
    21481 gcaattgatg ctaagctagc tgacattgac caagaaatta ccggtatcat cactgttttg
    21541 ccaaatactc cccatgattc agttcctatt ggagctgatg aagaggacaa tgtagagatt
    21601 catcgctggg gaaagccacg tcagtttgat tttgacatca aggcgcattg ggatcttgga
    21661 gaagccttag atatccttga ttgggagcgt ggcgcaaagg ttaccggtgc tcgcttctta
    21721 ttctataaaa atcttggtgc aaggctggag cgtgcccttt ataacttcat gcttgatgag
    21781 cacctaaaag agggctatca agaaatcatt cctccttata tggttaatca tgactctatg
    21841 tttggcactg gtcaatatcc aaaattcaag gaggatacct ttgagctaga tgggacaaac
    21901 tttgttctta tcccaactgc tgaagtccca ttaaccaatt actatcgtgg tgacatcata
    21961 gatggtaagg agctgccaat ctactttact gcaatgagcc catcatttcg ctctgaggct
    22021 ggctctgctg gccgcgacac tcgtggcttg attcgcttac accaattcca taaggtcgaa
    22081 atggttaagt ttgctaagcc cgaaacatct tatgaagagc tggaaaaaat gaccgccaat
    22141 gccgagcata ttctccaaaa gctaaagctc ccttatcgtg tcttggctct ttgtactggg
    22201 gatatgggct tttcggccgc taaaacctat gatttagagg tttggatccc tgctcaaaac
    22261 acctatcgcg aaatctcaag ctgctcaaat accgaagatt tccaagcacg ccgcgcacaa
    22321 attcgctacc gcgatgaggc agatggcaag gttaagctac tgcacaccct aaatggctct
    22381 gggcttgctg tcggacgtac cgtagctgct atcctagaaa attaccaaaa tgaggacggc
    22441 tcagtgacga ttccagaagt gcttcgtcct tatatgggtg gactagaggt gatcaagcca
    22501 cgttaaagcc aaagactggc cggataaggt gccaacaaga cgattaatgg gctctatcat
    22561 ttctgtagta gataaggaca cagtagaaat gatagggctt ttttctatgt acaaaaaagg
    22621 ctctttatca attgtagggg gacaaagagc cgattaatga gattgatcct aacaataaag
    22681 aagacctctg taactcctag ctaactgcta gccttacaga ggtctttttt gatgtcctta
    22741 atattttcta aagcgctggt agcgctgatc caataattcc tctaagggct tggcctgtag
    22801 ctgagtgatt tcgtcaatta agtgtgattt tatcatctca acaatctcac tcgaaaaata
    22861 accccgctcc ggaataatcc gatcaatgac gcccatttga tacagctcag ctgcggtaat
    22921 tttcatgagc tcagcagctt cagtagccct agagccatcc ttccagagaa tagaggcaaa
    22981 gccttctggg ctaagaacag cgtacatggt gttttccagc atccaaacct gatcagcaac
    23041 agctaaagct aaagcaccgc ctgagccgcc ttcgccaata ataatagcaa tgataggaac
    23101 cttgaggtca ctcatttcca tcaagtttct agcaatagct tcaccttgac cgcgctcctc
    23161 agcacctacg cccggataag ctcctgctgt attgataaag gtaatcactg gacgaccaaa
    23221 tttttcagcc tgcttcatta agcgtaaggc cttacgatag ccctcagggt gcggctgccc
    23281 aaaatttcta gccagattat cttgaagatt ttttcctttt tgaataccaa tcactgtgac
    23341 cggttgatca gccaaatagg caatcccacc aacaatagag ccatcatcag caaactgacg
    23401 atccccatgc aactccataa actcatcaaa aatcaggctg gcataatcta gagctgtcat
    23461 tcgaccctgg tcacgcgctt cctttaatat tcttgcgacg tctgtcatga tacacctcca
    23521 tgaaatgcca ccaaatgagc aatccgatca cgcaggtcag tccgcttcac aatagcgtca
    23581 acaaagccat gctcttttaa gaactctgcc ttttgaaaat catctggtaa attttctcta
    23641 actgtcgtct caatgacgcg tcgaccagca aaaccaacca aggactgggg ctctgcaata
    23701 atcatatcac cctccattgc aaagctcgct gtcacaccac ctgtggtcgg atcagttagg
    23761 atagtcaggt aaaaaagccc agcatttgaa tgtttcttta tagctgcaga aaccttagcc
    23821 atctgcatca gactcataat gccctcttgc atacgggctc caccagacgc tgtaaaaata
    23881 acaactggga gccgctcact aatagccagc tcaaataagc gagtgatttt ctcaccaaca
    23941 acggtcccca tgcttgccat gataaaatgc gaatccatga tggctagagc aagcctttgt
    24001 cccttgacca gagctgttcc agtcaggaca gcctcatgca agccagtagc ctgcctggcc
    24061 ttttgcagct tggcttggta gtctggaaat cttaatggat ccttggtttc aatatctgta
    24121 aacaattcct gaaaagagcc ttcatcaacg gttaaagtca agcgctcctg agcagaaatc
    24181 ctaaaattat aggagcaggt cggacaaatc tttgccggcc ccagatcctt ttgataaatc
    24241 atgtgcttac aggcaggaca cttggcaaat aattcgtctg gcacctctgg aacattacga
    24301 ctgacagagc ttttgagaga attattggga gtaatacgga tatatttgtc ttttttacta
    24361 aataaggcca tatctactcc taatctttat tgtagctggg taaaaaggtt tccatcaaaa
    24421 acgacgtatc gtaatcaccc gcaatcactt gcttgtctga aatcaagtcc atctgaaaat
    24481 caatattggt cataatacct tcaatctcta actcaaacag agccctttgc atcttcatca
    24541 aagcatcaaa tcggttatct ccatgaacga taatcttagc aatcatacta tcataataag
    24601 gcggtatcgt ataaccactg taaacagcag aatcaatcct aagcccaaca cctccgcttg
    24661 gtaggtaaag atctgtaatc ttaccagggc ttggtgcaaa attaaagctt ggattttctg
    24721 cgttaatacg acactcaata gcatggccag taatcacaat atcctcttga cgaactgata
    24781 aaggaagacc tgctgcgatc cgcaattgct ccttgacaat gtcaacgcct gtaacaaact
    24841 ctgttacggg gtgctctacc tgaacacgcg tattcatctc cataaagtaa aaatcaccgc
    24901 tggcttcatc taataagaac tcaattgtgc cagcattctc ataggacacc gccttggcag
    24961 cacgaacagc agcttcaccc atcctttgac gcagtgttgt gccaatcgca atcgaagggc
    25021 tttcctccag taccttttga ttgttacgct gtaaggagca atctctctct ccaaggtgta
    25081 tcacatgccc ctgtgaatca cctaaaattt gcacctcaat atgccttgcc ggataaataa
    25141 ccttctccaa atacatggca ccattaccaa aggctcctaa agcttcttga ctagcagcgt
    25201 taaaagcagc ctctaaatca gcctcggatt caacctttcg gattcccttg ccgccaccgc
    25261 ctgcagcagc ctttagcatt actggatagc caatctgcct tgcaatctca agagcctctt
    25321 gggcattgta aacctcgccg tctgagcctg gaataacagg aacacctgcc ttaatcatct
    25381 cagcgcgggc gttgattttg tcgcccattt tatccatgac agctcctgag gggccaataa
    25441 acttgatgtt catttcctcg cacatggtca caaattttga attttcactt aaaaaaccaa
    25501 accctgggtg gatagcctgc gcccctgtca ccacagctgc tgataagaca gaattcatat
    25561 tgagatagga ttcctttgat cttgacggtc caatacagat ggcttggtct gccaagatcg
    25621 tatgtaaagc ctctctatca gcctcagaat aaacagcaac tgtggaaatg cctaattctc
    25681 gtgctgcacg aataatccgc actgctattt caccacgatt ggcaattaag attttgttaa
    25741 acataggttc ttttttcctc cacagacgat tagtctttta ctgcccaaaa gcaaaggtca
    25801 aggtcccact agctgctaat ttgccatcaa cctctgcctt ggcctcaaca actgctattg
    25861 tcccacgacg cttaataaac ctagctgtca tgactagctg gtctcccgga accacctgct
    25921 ttttaaattt taccttgtcc ataccagcgt aaaaaacaag cttgccttta ttttcctctt
    25981 ttgatagctc caagacgcca gcagtttgtg ccaaggcctc catgatcaaa acacctggca
    26041 tgactggata ctgaggaaaa tgaccgttaa agaagggctc attgatagtg acatttttga
    26101 tggcaacaat ttcatcgtct gaagcctcta aaattctatc aacaagcagc attgggtagc
    26161 gatgtggcaa tgcctcttga atctgtttta tatccatcat ttaatgcgta ccaatccttg
    26221 tccaaactca accacgtcct cattggccac taaaatctct gtcacgatac cgtcgcaagg
    26281 agcaggaatc tcgttcatga ccttcatcgc ctcaacaatt aacaatgtct gtcccttttt
    26341 aacgctatca ccaacagtaa caaatggagg cttgtcagga ccggcagcaa gataggccac
    26401 accaacaaga ggactgtcaa ctacttctcc ttctggctct tgcagacctg aagaagcagg
    26461 gattgattcc tgtttagaga caatctcctg cgtcaggcta ataggggcta cctcctggtg
    26521 caaagtaaca ggctcaggag ctggagctgc catcggacgg tgctcatttt tactaaataa
    26581 cagctcccca tcacttgatt tgaatgaaaa ttcgcgtagg cttgacgcat caaactgtgc
    26641 catcaaatcc tttatctctt gaatattcat tttaatcctc ccaacgctta aaggctaata
    26701 cagcgttatg acctccaaag ccaaaggtat ttgacatggc ataacgaata tcggcttctt
    26761 ttccttggcc aaaaataaca tttgcttcaa tatcatctga cagctccttt gtcccagctg
    26821 tcattggaac ataattgtga cgtattgctt ctatggttgc aatagcttcc acagcaccag
    26881 ctgcccctag taggtggcct gtaaaggact tggttgatga gacaggaacc tctttaccaa
    26941 gcactgcaac aatagcctga ctttctcctt tttcattagc aggagttgag gtgccatgag
    27001 cattcacgta gtcaatagct gctgcatcaa taccggcctc ctgcaatgct agattaatgg
    27061 ccttacgagc accaagtcct tctgggtgtg gtgaggtcat gtggtaagcg tcacaggtat
    27121 tgccgtagcc aacaatctca gctaaaatag tcgcaccgcg cttttgagca tgctctaagc
    27181 tttccaaaac aagcatacct gatccttcac ccatgataaa accgtttcga tccttatcaa
    27241 atggaataga gctgcggctt gggtcctcag ttgttgacaa ggcagtcaag ctctggaagc
    27301 ccgcaatggc aaattttgta atggctgcct ctgatcctcc aaccatcatc acgtcttgaa
    27361 gaccaaactt aattgtacga aaggcatcgc caatagcatc gtttgaagag gcacaggctg
    27421 tattgattga cttacatacg ccttgggcat tcagcttcat ggcaacatta ccagccgcca
    27481 tatttggcaa ggcctttggt agagtcatcg gcttaacgcg ctttggtcct ttttcatgta
    27541 accgaatcac ctgctcttca atctcttgaa tgcctccaat accagacgct acaataacac
    27601 caaagcggtc agaatcaatc gcttcaatat ctaggccagc atgttcaatc gcctctgtcg
    27661 cagcatataa ggcatacaag gaatacatgt caaagcgatt tagatccttt ttgacaaaat
    27721 acttatcaaa tggaaaatcc tgaatctctg ctgcattctt aacagcgaag tcactcgtat
    27781 caaattttgt gataggctta ataccaatat gacctgcctt taagcttgac caaaactcct
    27841 ctggagtatg cccaattggg gaagtcacgc cataacctgt tacaactact ctgtttaatg
    27901 tcattttaat acctctattt tattgcattg tcatgccgcc gtcaatggca agcacctgac
    27961 cagtaatata atcctgacta gctaggaagc ttgctgcctg agcaacctct tgccccttgc
    28021 caatacgctt cattgggatt tgatttaaga tttgctcttg catcttttca gaaaggacac
    28081 ctgtcatatc agattcgatg aagcccggtg caatcgcatt tacccgaatg ccacgcgccg
    28141 caacctcacg agcaactgac ttggtaaagc caatcaagcc tgccttggac gctgcataat
    28201 ttgcttgacc gatatttcct gttaggccga caacactaga cacattgatg atagcaccct
    28261 gacgagcctt tgtcatcggc tttaagaccg attgtgtcat gttaaatgct cctgtcagat
    28321 tgattttgag aacacgctca aagtcctcct ctgacatctt aagcattaat ttatcattag
    28381 tgatgccagc attgttaatc aaaatgtcca cagagccaag ctgctcaata gcctcatcaa
    28441 ccattcgctt agcatcagcc ccctctgaaa catctcctga gatcggcaca accttcacac
    28501 cgtaatcctt aaaggtctcc accagctcat cagaaatcgc tgagcgacca ttgagaacga
    28561 tgttggcgcc tagtcctgca aattgatgag ccattgctag tccaatgcct cttgttgacc
    28621 ctgtgataaa aacgtttttt cctttaattt ccatagctta gcattccctc ctattttccc
    28681 aaatacaatt gtaggcttgg catatcttca acactgctgc atagcagctt tttgtcgatt
    28741 tttttaataa agcctgttaa aaccctgcca gggccaatct caacaaactg ggtgataccg
    28801 ttagccttca taacctcgat actatcataa aaacgaacag gctccatgac ctgacgcgcc
    28861 aataattctg caatccgatc cttttccatg accttagcct ctgtatttcc aaccagtggc
    28921 agatcaaagt cctgaaattg aatcttgctg agctcctctg ccaacctttg actagcaggc
    28981 gctaaaagtg ctgtatggaa aggtcctgag acattcagcg gaattaaacg cttcactccc
    29041 tttgctttta agatttcaag tgccgcattg acagcctcag ctgtcccacc aataacaatc
    29101 tgtcctggcg tattatagtt agcaggtgac acaacaccaa ccgaagaagc ctcttgacaa
    29161 gcctcctcaa taagcctagc ctctgtattc atcacagcta ccatcttacc agagccagca
    29221 ggcgctgcct cctccataaa gcgtcccctt tttgcaacta gctctagggc agtctcaaaa
    29281 ctcagaacac ctgccgcaac tagagcagaa tattctccaa gagaaagccc cgccaccata
    29341 tcaggatgaa ccccataaga ggttaagata cgataaatgg agactgaagc ggttaagatt
    29401 gctggctgcg tgtaggctgt ctggttcaac cgatcctggt cggtatcaat gagcttgcgt
    29461 aaatcatagc ctaaaagctg actagcctga tcaaaggtgt cacgagcaat ggcatattgg
    29521 tcatacaaat ctcttgtcat gcctagtgtc tgagcaccct gaccagcaaa taaaaaggct
    29581 gtttttgtca tacttctcct tatttatatc gtttcgtttt tgtcatcagc tgcaagagct
    29641 tgccagcgct tagcttcttg actaatcact gctgctgcac catagtagat atcctttagg
    29701 atggcttcac agctttcttc tgctctaatt aagcctgcaa tctgccctgc catgacagag
    29761 ccattgatca catcaccatc aatcacagcg ttgcgcagag ctcctgctcc catttcttcg
    29821 atgtcactag cagccttacg atctgctaaa aattcttttt cagccttagc ataagctgat
    29881 gttagcttat ttttgataga gcgtaccgga tgaccaacaa cttgagctga aatgacagta
    29941 tcaatgtcct tagccttcaa aattttatcc ttaaagcttt ggtgagcatt agattccttt
    30001 gccacaacaa atcgagttcc aacctgaaca gcctcagcac ccagcataaa ggctgctgct
    30061 gcacctcgac catctgcaat cccacctgct gcaataactg gaatagaaac agcatctacc
    30121 acctgcctaa ccaaggtcat cgttgtcaat ttaccgatat ggccaccagc ctccattcct
    30181 tcagcaataa cagcatcaac gcctaatttt tccatgcgct tagccagggc aacgctagga
    30241 acaactggaa tcacgataat acctgcctca tgaaggcgct ccatgtattt ccctggattt
    30301 ccagcgccag tggtcaccac cttgacacct tcttcgatca ccaaatcgac aatgtcatct
    30361 gcaaagggag atagcagcat gatattaacc ccaaagggct tatctgtgat cgctttgaca
    30421 cgatcaatat ttgccttgac cacctcttta ggagcgtttc ctccaccaat gatcccaaga
    30481 ccaccagcat tggagacagc acctgctaga tcaccatcag ccacccaggc catacctccc
    30541 tgaaaaatgg gataatcaat attaagtaat tctgtaatac gtgttttcat aataaccttc
    30601 tatgcaaaga aatcaggaga ataatttgat aatcaaacta tcataataag aagaaagagc
    30661 gagttagagc ctgaaagagg gtctaatctc accctgatgg ttcgattatt acatatcaat
    30721 tgaccaacta aagcagttca ttaatcagca ggctggttaa tcagtattct cgcttgtttg
    30781 agctttattt tgttttttct tcaacgtagg caacaaggtc accaactgtg tttaagcctt
    30841 cttctgtttc gatttgaatg tcaaaggcat cttcaatttc tgagatcact tggaaaacat
    30901 caagtgagtc agcatctaaa tcatcaaagg tagtttctaa ggttacttcc tctgcgtcct
    30961 tgccaagctc ctcaacgata atttcctgta ctttttcaaa tactgccatt ttatgtctcc
    31021 ttaatataaa tatttatttt ataaatgtgc taggcacatg atataactag attttaacaa
    31081 ttagactgcc ccatgtcaaa cctccaccga agcccgacag taaaatatgc tggctgccgt
    31141 ctaatttaag ctgtccattt tggactgatt cagatagcaa aatcggtata ctagctgcac
    31201 tggtattgcc atagtgcatc atattttcca gaaatttctc tcttggcata ccaattttct
    31261 tagccatctt atctaaaata cgccgattgg cctgatgtaa aagcagatag tctaactcct
    31321 ccttggccaa gcctgattgc tcaataattg ctgtaatgct ccttgaaaca tctctaatcg
    31381 caaagtcaaa gatagcacga ccatccatct gaagaaagga gttgacctcc tgtccttgag
    31441 aaaatggtga gcgcagactg ctctgacctg atgtcaggct ttgaccttgc gcaccatcag
    31501 tatgtaaggc ctcagctaga aaatgctgct gctcgctggc ctctaataaa accccaccag
    31561 caccatctcc aaataaaaca gctgtgcttc tatcctgcca atcaataatc ttagacaggg
    31621 tctctgctcc aataaccaag cctctttgat aagcccctga tgcaatcaac ttatccgcca
    31681 ttgctaaggc aaagacaaag ccactgcagg ccgctgtcat atcaaaagca aatgcattag
    31741 tagcaccgat agcagcctga acctttgctg ccgtcgatgg catgctagca tctgggctaa
    31801 tcgtagcaac gatgataaaa tcaagtgcag tcgcatcata tcctgaccct gctaacaatt
    31861 gctctgctac ccgaatggct aaatcactgg tcatctccac agtggaaatg tgacgcttct
    31921 caatcccagt ccgtgacgaa atccattcgt ggctggtgtc catgatttgc gacagatcgt
    31981 cattactaat aacctgctta ggcgtataat gagctacctg actaattttt gaaaagacca
    32041 ttaaaccaaa tcctccaaaa actgatgtaa gttccccaag ccacgtaaca gggcttgcat
    32101 ttcgtcctca ttcatatcag cgatcacatg accgaccata tttttatgga atcttgcatg
    32161 gagacgatcc agaagacgcc cctttttggt cagtgacagg taaacaaccc gtctatccac
    32221 gcttgatctt gttctttcaa tatagccctt tagctctagc ttgtttaagc tagtggtaac
    32281 cgttcctaag gtaaccatga gctctcttgc gatgtcactt ggcgttacct gctgatattt
    32341 tccaataatc tcaattgtgt gcatctcctt tagagaaaca tcattaaatt gacttgtttt
    32401 taagctcatt tcctcaataa ccaaaattct gttgaaaata tcaactaaat attgattaat
    32461 cttattatat tccaagtaaa cacctcccta gctgtaaaat actttgacta tcaaagtata
    32521 tcagacatca aagtattttg caagcacata agagctattt cccccgaaaa tttggccgcc
    32581 tcctatctcc ataagccctg acgccctctt taaagtcctc cttaaaggcc aattcctctt
    32641 gaatagcaag ctctttttgg gcataatcct cccaacctgc aaaaaagctt tgccatacca
    32701 aagatttcat gccggcgtag gaatttgaag agccacgcct caaacgcttt aacagctgac
    32761 tacaggtctt atcaagctta tctgactcag cagctcgata gacaaatccg tactcaagcc
    32821 ctttttctgc tgtgaccccc tcaccggtca tcaccagatg agtcgctcta tttagaccaa
    32881 cggcacgtgt taacaagaaa agaccaccag catctggcgc taagccgaca ttaacaaagg
    32941 cctgaataaa ttttgtctgg gtgctagcaa tacaaaaatc caccgctaag gcaatattaa
    33001 aggccgcacc agccaccgca ccatcagcac agaggataac cggctttggc aattgcttga
    33061 tagcaaagga aatatcctga accagctcag caatcctaac tagagactga acatcatctc
    33121 tttcaacagc attttgcatc tcaaccaagt caccaccgac tgaaaagacc ttgccctttg
    33181 ccttaatcac taaaaagcgc agagaggggt tatccttaac caacctaata gcctccagaa
    33241 tctcctgaca ggctggaatg ttaaagccat tagacacctc tggacgattt aaggttaaaa
    33301 tggccagatc ctcttcaagc tcaaaaatga tattttgaaa cgtcatatca ctcctctttt
    33361 ctgacagctt atttgattac caaataattt tatgaccaaa taatttgaca atcaaattaa
    33421 ttactagact atagtacact agaatcagtc gttatgcaag aaaaagattg taaaaaatac
    33481 attaaaattg actgcgcaat ttaaagcatg cagccctaaa accaagctca gacctagcct
    33541 ctatacctct aataaaagag cctaagacaa aagtgtccta gactctgaaa ctttggcatg
    33601 tgctatgctc aaccattcta tacaattgtg atcaatcgct catagagtgt gtaaacaaga
    33661 cccgcttaaa tatcctctag agcgtctttg accttgtcaa agaaaccttt tttctttgga
    33721 gcaatcggct tttcgccact agcctccgca aaagccttca aggcctcctt ttgagcctca
    33781 ttgagcttgg taggcgttac aatgtttaca gttacatgct ggtctccttg gcctccgcct
    33841 cgaagcttag gagccccctt gcccttcaag cgaaatacct taccagtttg tgttccagcg
    33901 ggaatagaca tggcaacatc accatggacc gttgggatat ctactgtatc tcccaaagca
    33961 gcctgaacaa atgaaatatt caagctgtag taaatagtag agccattgcg ctcaaactgt
    34021 ttacttggaa gcacgtttaa aataacgaac aaatcaccat aaggtccacc attaaagcct
    34081 gcttccccct gaccctgtag gcggatttgt tggccggttt caacacctgc tgggattttt
    34141 actgaaacct tatgaacctt cttttcatga ccagttccat gacaggtatg gcaaggctct
    34201 ttgatttctt gaccgctgcc atgacagaca tcacaggtca cctgacgacg catcatgcca
    34261 agtggggtct gcgtatcaac attgataacc cctgagccat gacatttacg gcaggttgta
    34321 ggacttgttc caggcttagc tcctgagcct gcacaggtgc tacaggttga ttcacgatga
    34381 tagctgacct ctttttcggt accaaaaaca gcttcctcaa aagaaaggtt taccctatat
    34441 tgaaggtcat cgccctgacg tggagcattg ggattacgca taccaccacc gccaaaaaag
    34501 cttgagaaaa tatcctcaaa gccgccaaag ccaccaccat cgaagccgcc aaaaccgcct
    34561 gcgccaccac caaagccacc gtttgctccg gctgccccgt attgatcata ggctgcacgc
    34621 ttttgtgaat cgcttagggt ttcataggct tcctgtacgt ccttatattt ttgctcagct
    34681 cccggctctt tattgatgtc tgggtggtat ttcttagaca tcttacggta agctcgttta
    34741 atatcatcgg ccgaagcgtc ctttgagacc ccaagacgat catagtattc cgtattattc
    34801 atttattctt tccttcattg acaaaaacag acggagcgag gcgccccgcc tatttgattt
    34861 ttatttattt agccttgcta tgctattttc tagcaattag gggaggggac tatcgcctca
    34921 gtttctagct ttactgagcg accttagctc ctcacagctt atttttcagt gaactcacca
    34981 tctacaacat catcgccact gtttgttgag cctgtatctg ctgcaccttc tgcaccagcc
    35041 tgggcttgtt gtgctgcggc tgcttgctcg tacattttaa cagcaagggc ttgtgctttt
    35101 tcattaagcg cttcaagctt agctttcata tcatcaaggt cgcctgactc ttgagccttc
    35161 ttaagctcat caagagctgt ttgagcagca tcacgctctg tgtcaaagcc tttgccttca
    35221 gtttctttaa tagtcttttc agttgcaaag atagcctggt caacttcatt tttaaggtca
    35281 acctcttcct tacgttttgc atcggcttca gcattggctt cagcgtcttt catcatgcgt
    35341 tcaatttctt cttcagaaag accatcgtta gatttgatga caatatgttg ttctttttga
    35401 gtacctaggt cttttgcctt aacagaaaca ataccgtttt tgtcgatgtc aaaggttact
    35461 tcgatttgtg ggataccacg aggggctgca ggaatgtctg tcaattggaa gcgtccaagt
    35521 gttttgttat ctgctgccat tgggcgttca ccctgaagca cgtggatatc aacagctggc
    35581 tggttgtctg ctgcagttga gaagacctgt gatttagagg ttggaattgt tgtgttgcgg
    35641 tcaataagct ttgtaaagac gccacccatt gtttcgatac caagtgacaa tggtgtcacg
    35701 tcaagaagaa caacgtcttt aacatcacca gtgatcacac caccttggat agcagcaccc
    35761 atcgctacaa cttcatcagg gttcactgat ttgtttggct ctttgccagt ttcagcctta
    35821 acagcttcaa ccacagctgg gatacgagtt gaaccaccaa caaggataac ctcatcgatt
    35881 tctgacaagc tcaagcctgc atcagacagc gcttggcgaa caggaacctt cgtacgctct
    35941 actaaatcac gagtcaggtc atcaaatttt gcacgagaca ggctcatctc taagtgaagc
    36001 ggaccagcag cgccagcagt gatgaatggc aatgaaattt gagtttgagt gacacctgaa
    36061 aggtcttttt tagctttttc agcagcgtcc ttcaagcgtt gaagagccat tttatcttgt
    36121 gataggtcaa taccgttttc tttcttgaat tctgctacta agaaatcaat gattttttgg
    36181 tcaaagtcgt caccaccgag cttgttgtca ccagcagttg caagcacatc aaagacacca
    36241 tcacccaatt caaggataga cacgtcaaag gtaccaccac caaggtcaaa gactaagatc
    36301 ttttcttctt tatctgtctt gtcaagaccg taagcaagag ctgctgcagt tggttcgttg
    36361 acgatacgtt ctacctcaag cccagcaatc ttacctgcgt ccttagtagc ttgacgttgt
    36421 gcatcgttga agtaggcagg aactgtgata acagcctttg ttaccttttc accaaggtag
    36481 tcctctgcat agcctttaag gtattgaaga atcattgctg agatttcttg tggtgtgtat
    36541 tctttaccat tagcagcaac cttttcagag gttcccatct ttgatttgat tgagataaca
    36601 gtgtcagggt ttgtcactgc ttgacgcttg gcagcgtcac cgacaatgat ttcaccgttt
    36661 ttaaatgaca ctactgaagg ggttgtgcgg ttgccttctg ggttggcaat gattttgctt
    36721 tctgttcctt caagaactgc tactgctgag tttgttgttc ctaagtcaat accgataatt
    36781 ttagacataa tattttttcc tcttttatat atttatgata ctcctcttat gtggcacgga
    36841 cgctagcagc ttcctatgga atctcatagc tgaaatttga gcctaaagtc tcaaattttc
    36901 cgagtcataa aacactagtg ttttatgact tttgccacgg cgaagagtat cggtaatgct
    36961 cacttcgttc gcttttgcta gcgcaaaaag cagcaatctt atttcttatt ttcatagttt
    37021 accgtcattt cggacatgat tcattttatt gattagctat catcacggga taattgcgac
    37081 gtgagatagc aaaatcgata ccattttgct atcgagctag taaggagtct aggcaagccg
    37141 ccacagcggt tgccgtctaa tgacgagcca tttcaatggc catcattagt gactagttgt
    37201 acacaaccac catcgctggt cttagtaagc gctcatgaag cttatagcct ttttggaaaa
    37261 cctgagcgat actatctgct gggtggtcat catctgctgg tagggtttgg actgccatgt
    37321 gcagattgtg gtcaaaggct tccacaggaa cctcttcaat accttcttct ttaagggctt
    37381 gaacaaggct ttcttgcacc atttctaggc cttttttgac atcatctgtc agaccctcaa
    37441 cagccaaagc acgctccaag ttatctaagc ttggaaggat ttttttagct aaatcctgtg
    37501 aacgatagcg ctgcaagctt tggcgttctt cattcgcacg acgctgaata ttttgcattt
    37561 ctgcgtgagc tctgaggtat ttattttcaa aatcttctgc tcgctggaga gccaactcta
    37621 gctcagatgg ttcctcggct gcttcatcag caataagctc agctgattga tcagcttctt
    37681 caactggctc tactgcttcc tcagcagcct catcaagaat gtcctcttga tccttgagct
    37741 cttcttttgg ttttttagac aaggtgtcta cccctttctt acattttctt aaatcatatt
    37801 aaggccttag tgaacctcat aatggttgct gtttaagtaa cggtaataat ctcttagctt
    37861 cacagccagt agctgaccaa tcacattaat caagctaaca ctacgacgat aatccatatc
    37921 aactggccca attaagctta agaggccaaa tcctctgtat ggaattaaaa acttgtaggt
    37981 cagcaaggtc acgtttgcta gggctggctc actgctgtca gcaacctgaa ccgttgccat
    38041 ctcttcctct gatagactct gtctgataga tagggctaag cgctgctcct catcaagaaa
    38101 ctgataggtc gcaagaccag catagtcaag ggcagcaacc ttgccagaga caaaaatcgt
    38161 ttctcgaaaa agcccgacaa agatataatc aaacaaatcc aaaacattgt ctgtcaccgt
    38221 aaaatacttc tgaacaatct gagggatttc ggttcgcagc ttgtaatgaa cagtcataac
    38281 atctttgcca agtaagcgat cagcaacaat gcccttaagc accagcaaat cacgattcat
    38341 aaaattctta ggaatggcaa actgtacggt caacggcttg gactcatcta agctcaaaac
    38401 tgccaaggca tcatgactag atagctgaac aatatcaaag cctgtcagcc tttgccttgc
    38461 aggctcaaca tctaaaatcg ccgccgtata gccggtcgta tccgatagca tctggctggc
    38521 tcttagcaaa acgtcctcca gcttaaaggc ctcaaaatca aaggccttga ccagctgata
    38581 aaggtcctgc tcatcaatgc tgccaagatt aagagaatgc tctacaaaat atttaaagcc
    38641 tgccgcactt ggcatgcgcc cacttgatgt gtgagccttc tccagcaatc ctagtttttc
    38701 aagctttgcc atgtcatttc taatagtggc actactagaa gcaataagtg actgcaaagc
    38761 cttagagcca actggttcat gggtctgtgt aaataaatct acaataagat tcaaaatatt
    38821 agattgtctc tctgtgatca caaaccaatc actccctttc tgttagcact ctatacatcg
    38881 gactgctaat ttataattct attatatcct tttaaactag catgtcaaga aaaaaactca
    38941 aaaaattagc actctttttt tagagtgcta atttttataa aacattgaca gtgttgcctt
    39001 tgacattatg cttgaaagaa gtaatagaga gccacttact acctctcaga ctggtattgg
    39061 cttctcccga ctcgctagct aaaaggagcg ctaagctgta agggggatta gcttaactgc
    39121 ctgaagcctt aaggcctaac aatcaagcct ttagtagagc aggataaatc aggctgcgtg
    39181 ctcacagctc ctactcttaa ggcttacacc ttcaagctga tagaaagttg caatacctac
    39241 taaagcaaat acctgagctt accggttgtt tcggtgtctt tttcatctcc tcaatcatca
    39301 tagcttgtca aacctcttgc ttcaatcagc tgcacaagcc tttgggcata gcccttatca
    39361 tcagaatagc gataggtctg cagactttta gcaggttttt tatacccttt ttcggttgct
    39421 aggctttggt aaagcttttt ctcctcgcct gtgccttgac taagccatga taagtaagct
    39481 ctgatagagt cctctctgtc ccgatagata gcataggctg tcttgtgctt tgaggctgct
    39541 tgcttcttga ggctaatgga agcctgccct ggagctggct gcagtgaaaa aaggttgtgg
    39601 tatttggccg ccaacagggt tctgccataa ttggtttcta aaataatctg accaatcaaa
    39661 atagaaggac gaatgccata gtttttggcc aatggcttga cctccttagc aaccaactgg
    39721 ataaattgcc tctctgtata gggaacagac atctcctgac tggccgatgt gcctttggca
    39781 ttgaacagca agggaccaat caaagccacc ataatgaaca ctaaaaacac tagaaaatag
    39841 gaaaatttaa gtcgttttct cattttttct ccttcaatcg tgttaggtat tcttctaggc
    39901 tgaggctatg agcggtaatg tatagggcag aggctttacc aacatagcga taatgccagt
    39961 cctcatactc aatccctgtg ctagtctgct tcccttttgg atagcgcaaa ataaaaccaa
    40021 attgtggagc tattttttga atctcctgtg ccaccttagg atcactagcg tttaagttat
    40081 ctactgtgct catatcaatg gctagaccag tctgatgttc actagtgcct gctggctggg
    40141 catatttccg aaccaaggct tcagctgcct cttgggtcag gctaggatca tttgccagct
    40201 cttgggcaat ataagactga taaagctctt cttgctggac aaccgaacga taaccagcaa
    40261 tcaagtgctc ctgaggttca atcgtctgcg ccgctgctag aaaatcagcc gtctcctgct
    40321 caatgcgctt atcaatagga atcccattaa tctcaaccaa ctcaggactc atttcctctt
    40381 gagggtgatc gcgattgaca aggaccagct gccagtccgt agttgatacc tttggcagat
    40441 cagtagtctt tttagcctgc ttagctgcct ttggggcagg tactgtttga ttagccttgg
    40501 ggcctacagc ctgtttttca ggcttgataa agaggtaaac ccctgataaa aacaacagga
    40561 cgaccaaggc ctgtaaaagg actcttatag tgttattctt catctcttat tgactcaatt
    40621 atctcacgac cacgatagcg gtagctcata tctccaatcg ttttgatggt aaactgccca
    40681 ttctcatatt ccacaacagt gacgcttcca ttgtcaatgt attgcttttc cctatctggg
    40741 tcaattagcc acataaaggt tccaatggtc atgccatgac taaccacgat agcattgcca
    40801 cctcctgcat tttcaacagc aagcgcgata gcctcaaagc cctcatagat acgcttgctc
    40861 aatacctccc agggctctgc ccagttagca gtatcaacct cgacaatact ctctgctaat
    40921 tctgaataag gcacatcacg cagattgtca cgattttcaa aggcctttgt tctaggtaaa
    40981 acacctaaaa acagctcgga atcataagcc ccatctagac taccaaagca ccactcacga
    41041 atccgcttat ctctagtgta gggtaaaaac tcattttcag actttcgtag aataatctcc
    41101 attgtctgca tggtacgacc tgaatcactc gaaaaagcag ccttgaatgg aataccagca
    41161 gccttcaaac caagtcccaa ttcacgaatc ccttcttctc ctgcctttgt caagggggta
    41221 tcactccaac cctgtgcacg accaatggtg ttgaacatcg tcttgccatg tctgacaatg
    41281 tataatcttg tttttgtcat aatgaacctc caaagtctct ctgctattat agcattaaaa
    41341 gaaaacactt gcaaaaccat gcaagtgcta gccgttaatt cttaaagcta tggataggag
    41401 ctggtatctg cccaccacga gcaataaagt cagccgatga atgcggatta acagccataa
    41461 ccggagctgt ccctaaaaga ccaccaaaag caatcatatc accctcctta ccctttggaa
    41521 taatacgaac agctgttgtc ttttgattaa tcaccccgat agctgcctca tcagcaatca
    41581 tggctgcaat ggtttcagac ggtgtctcct ctgggatcgc aatcatatcc aaaccaaccg
    41641 agcaaatggc agtcatggct tctagctttt caagattaag cgagcctccc tgcactgctg
    41701 caatcatgcc ctcgtcctct gatacaggga taaaggcacc tgacaaccca cccactcggt
    41761 tgcaagccat gacaccaccc tttttgactg cgtcattaag taaagctagg gcagctgtcg
    41821 tgccatgtgt gccaactatt tcaagtccca tctcctctaa gacacgtgcc acagagtcac
    41881 caactgctgg agtgggagct agcgacagat ccacaacacc aaagcccaca cctagccgct
    41941 cacttgccat ctgtcccact agctgaccga tacgcgtgat tttaaaggcc gtttttttga
    42001 cggtctcggc tagaacgtca aagctttcac cacgaacctt ttccaaggct cttttgacca
    42061 caccaggtcc tgaaacacca acgttaatca ccgtatccgc ctcaccgaca ccatgaaagg
    42121 ctcctgccat aaaaggattg tcctcaacag cattagcaaa gactactagc tttgctgccc
    42181 ctatctcaga ggctttggcg gtttccttga tgatacgccc catgtctgca actgctgtca
    42241 tattaatacc agaccttgtt gatccaacat tgaccgaagc gcagaccttc tgtgtttgag
    42301 ccaaagcctg aggaatagac tcaatcaaaa tcttatcacc cttttgatag cctttttgca
    42361 caagagctga aaagccaccg ataaagtcaa ctccgatatc acaggcagcc tgatccagag
    42421 cttttgcaag cgacaggtag tcttctgcgt ctgttgccgc cccaataagg gctatcggag
    42481 ttacagagac gcgcttatta acaatgggaa tacctagttc tgctgcaatg tcatcaccaa
    42541 ccgccacaag attagctgcc tttgtcgtaa tcttttggta aatcttagcg gcagctctat
    42601 caatatccga atcaatacaa tccagcaagg aaattcccat cgtaatggta cgaatatcaa
    42661 aatgctgctc ctcaatcatc tcaactgttt cacgaacctg tctaatatcc atagtcatca
    42721 agctccttat atgttatgca tagcatcaaa aatcgctgcg ctttgaatat taatcgtcac
    42781 ctgcaattgc tttccataag cctgaagcac ctcacgcaga tgagcaaaat cctgcttttc
    42841 actgcttgag acaatggcca tcatggtaaa ataatcatct aaaacggtct gtgaaatgtc
    42901 atcaatattt aaccctaatg cagcaatttg tcctgaaaca cctgcgacaa tcccttgatt
    42961 gtccttacca acaactgtaa tgatagcttt catggcacac ctcctcaata tgtgttatat
    43021 tttatcacaa acaaaaagag aaagctatca gagacaagag gtctggtagc cccttgcaaa
    43081 aatagaacaa tgggtaccag aaaaaagagt ttgttatcca attgataccg tttattaata
    43141 tttagacttt ataatataat agcagctaat aaaagataag acgtttgaag ctgccaaaaa
    43201 agctgggtct aaggaagccc agcttttttg taggttaatt aagggatagc agaagattag
    43261 tcgggattgt aagaatagcc gtatcctctc ttaccacctc tatcagctag accatctaaa
    43321 tagccatttc cataattatc attataccct tgactatagt cattatattc ctttggacta
    43381 gactcatcaa accgcttagg ataatctcct ttgtgctttt tgccaccata tccatcctca
    43441 tagccaactc ggtaaccatc acgacgacca tgattgtagg ggtgttcgtc tttaagtttt
    43501 ggtgattcat cattttctcc gcttaagcct ttaccgtcta aatcttcctt tggcttattc
    43561 tctccatcta atccttttaa aggattttta cgattatttc cttctaaatt cggagttgat
    43621 gggggaccgg cttcacctcg ttcaccttgc tctggttcct tctgattctc accattcaag
    43681 cctggaagcg aaggacggcc ttgattatta ccactcaacc ctgaaagtgg gggaccagcc
    43741 tcacctcgtt caccttgctc cggttccttc tgattttcac cattcaagcc tttttctggc
    43801 agcttgggac tattgccctg aggctttggt tgaggctgcg ggctagaatt atccttacct
    43861 agatctaagt gctgtggctt tccttgtggc tgatggtgat gacctgaacc agagctgtta
    43921 cctcctctca gccccagtgg ctgggaaggc ccttgattag gaatagcctg aggctctgag
    43981 gcctgtccac tactatttcc ttggctgttc acactgagag actgaggttg attcccatga
    44041 tgacctgagc tctttgctgt cggctgggac gggctagtag cctgatgctg atgattagta
    44101 ggctgatctg aaggcttagg ctgcaagtta tcctttttcg gtggccgact gaccattgaa
    44161 tctgatgagc tcttgtgcga cttatcgtca tctccaatcg agctgactgg ctgctccttt
    44221 ggcctcgctt gatgggatga gccaccaaga cttcctaata aacctccaaa gacaagtgca
    44281 gctcccagca gcaagctggt caccactgca ccggcaaata gccattgttt tttggacttc
    44341 catgtgcgaa aacgtccttc tgtttttctc atactttttt aactctctcc atattttttg
    44401 gtaaaaatac caagaaatag tatatatagt caagacttta tcatatttct tttaaatttt
    44461 tatcatctga tatattcgat tgtttttaca aatctgataa ccaaaaaatc ctcgtatcat
    44521 actgatacaa ggatttttat atatttgaac gtcacaagta ctcctggctt attgtttttt
    44581 gccaaagagc gctgaagcaa caattatcac aatagctgct cctagaattg aagggaaaac
    44641 agccatgcct gccagctgaa taccccagtc gccaaacagc ttttgaccaa ctgcagagcc
    44701 tatcaaacca gcagcagtca ttgtgaaaca gcccatcgaa tggctttttt ctgttatcct
    44761 acctgcaacc atgccgataa tagctccaac aattaatgac caaaccatcg caaatctcct
    44821 ttatgttttg tcttattata ccataccctt gccttatatc agtcagatga tggtggtcgc
    44881 ttgatattaa gagcaagctg cttttttctc ttagtaagca ataagtctct cagcgatatc
    44941 acaagcactg ctattaaaat caaggccatt cctaacagat caatagggtg aaaaatctct
    45001 ttcatcagga taatcgcaaa gcagacagag gcaaccggct caattgaagc cagcaaggta
    45061 gccttgatcg gtccaatgat tgaagccccc tttagaaaaa aggtgtaggc aaaaattgtc
    45121 ccaataccga taatgccaaa cagggcccgt agattcccat aagtcattgc caatgggtac
    45181 tgccatgctc ttgtcaggat cggaaaaatc actcctccca tcagcatggc aagaccaaca
    45241 atcagcaagc tcccccagtc ggcaatcagc ttagcaggct tgatgacaca gtaagcatag
    45301 gtcaccgctg caaaaagccc ccagaaaagt ccaataggat tgattgccag atgggaaaga
    45361 tcaccatgac aggccatgat aaccgttcct aggatcgcta ggcaaatagc acagctctct
    45421 cccacagccg gcaggcgtct tgatttgaac gataggtaga ccagcaccaa aatgggggaa
    45481 aggtattgca ggactgtggc tgtaccagca ttagagtaac gaatagcaag cagataggca
    45541 tattgattaa gtgtgagacc aaatagactg taaatcaaca gctctcttaa aagccttttg
    45601 tccttgagta agctgatgac agcctctctt tgccgcacat aagccatagc tgacagcaca
    45661 agccctgaaa taatgagcct tagtgaggtc aaggcattga tgccgacccc atgagcaatt
    45721 aaatattgcc ctgacacccc tgagagaccc caggcgattc cggctagtaa aatcatggta
    45781 ctgccttttc catttcttga catattatct tcctcttttt aatccatgcc atgataaggc
    45841 cactcataat accttgatag ctctagccta gacttcacca agcctgctta acagtcatta
    45901 acaacagacc gataagctac ctcttacagc ttcggatagc gaggtattat cacagaattg
    45961 tcctaaagag cctaccatca taaagagcct gaaaactctg tttcagactc aatgccagtc
    46021 ataacgactc cttaatccag caatttttgc aattcttggg ctaacaattg ctgagctatc
    46081 tgtgggttgg cttgcccctt tgtggccttc atcagaaaac cagtaaaggc cttgtcagca
    46141 ttgcgcttgc ctgatttgaa atctgccaca gcagcctcat tgtcagcaaa cacctgatga
    46201 atgattggaa tcaagacagc tgggtctgaa atttgaacca agccggcctt ttccacataa
    46261 gcacgcgctg agccgccatg ctttgccaaa tgaacaaaaa ccttcttggc gatttttgat
    46321 gaaatcgtgc catcagtgat gatcgcaatc atttccacga gattttctgg ggtcaaggca
    46381 atctgatcaa tcgtcttgcc ctcagcattt aagaattgag ccatctcacc ctgaagccaa
    46441 ttagacacct gcttaggatc accaccaagt gccacagcct gctcaaagaa atcagacaaa
    46501 gcctttgttg ctgtcagctg acctgcatca taggctgaca agccaagagc attaatgtag
    46561 ctagctcgcc tgtctgccgg aaatcttgga agctctgcac gcatatcctc aatccatgcg
    46621 tcatcaatct caaacaatgg caaatctggc tctgggaaat agcggtagtc tgctgctccc
    46681 tccttgacac gcatgagaat cgttccctta cttgcctcgt cataacgacg tgtctcctga
    46741 cgaataacac cgccagagcg taggattttg gcttgacgct ccacctcaaa ctcaagcccc
    46801 ttacgcacat tgctaaatga gttcaggttt ttcaattctg tttttgtacc aaaggcctct
    46861 tgtccgtatg gtcgcaagga gatattggcg tccacacgca tggacccctc ttccatcttg
    46921 acatcagaaa taccagtata ctgaatgatt tcctttaggg cagtcaggta agcataggcc
    46981 tcctctggag agcgcatgtc agcctctgag acgatctcaa tcaagggcac tccctgacga
    47041 ttgaggtcaa cataggaata accatctgta ccatgcgtat ttttgccggc atcctcttct
    47101 aggtgagcac gctcaatacg gattttcttg gttgagccgt cctcaagagt aatatcaatc
    47161 cagccattgt agccaatcgg ctcatcaaac tgtgaaatct gataggcctt gggattgtct
    47221 gggtagaaat aattcttacg gtcaaagtgc atgtgctgat gaatagacat gttaagagca
    47281 agtgctgctt tgattcccgc atcaatgact cccttgttca tcactggaag gacacctggg
    47341 aaagaccagt caatcacatt agtgctggca tttggatcct ctccaaaatg agctgatgaa
    47401 ggtgagaaaa tcttagaatt ggtattcaac tccacatgga cctcaagtcc aataatggtt
    47461 tcaaaattca ttacctgtca cctccaaaaa tcataggctg ctgcttgtgg tagtcagtag
    47521 tcgcttcaaa ggctaccgct acctgataga tgacctcttc gctatatttt ggaccgatca
    47581 attgaagccc aacaggcaag ccatctgcaa agcctgctgg aatagagatt gcaggcaagc
    47641 ccgctagatt caccggaatg gtcaaaagat cagccaaata catggcaaca ggatcatgat
    47701 tcaacgtatc aagctcaaag gctgctgttg gtgctgttgg tcctaaaatc aagtcataat
    47761 cagcaaaaac cttctcaaag tcttgaatga tcagcgtccg aacctgacct gcctttttga
    47821 aataagcatc gtaatagcct gatgataagc taaaggtacc aagcatgata cgacgcttaa
    47881 cctcatcacc aaagccctga ctacgcgtct tgacatagat gtcctcaagg ctcttggcat
    47941 cagcagcacg aaagccatag cgaataccat caaagcgctg taggtttgat gaggcctcag
    48001 atgaagcgat gatataatag acagccaccc catacttgct atgtggcaga ctgacctcct
    48061 caatgatagc tcctagcttc tcaaaatgct tagcagcagc caaaaccgtc tccttaatct
    48121 taggatcaat gccttcgcca aggtattcct taggtagtgc aatcttcatg cccttgatgt
    48181 cttgaccgat cttaattgtg tagtcagcga tctgtacagg tgctgaggtt gagtccttgc
    48241 ggtcactccc tgcaatgacc gatagcagct gggcattttc tcttaccgtt ggcgcaaaag
    48301 gccctatctg atctagcgag ctgccaaagg caatcaagcc atagcgagaa acagccccat
    48361 aggtcggctt aagcccaaca acaccattaa aggctgctgg ctgacgaata gagccgccag
    48421 tgtctgagcc aagagataag cgaacctgac ctgaagctac tgctgttgca gagccacctg
    48481 atgaaccacc aggaaccctg ctatgatccc aagcgttttt ggttttcttg aaataagacg
    48541 tttctgttga gccacccata gcaaactcgt ccatattggt cttaccaata acaatcatat
    48601 ccttgtcgta ggcattagct accgctgtcg catcaaaaat cggctcataa ttataaagca
    48661 tcttagaagc agcagttgtc agaatcccct tggttgagat attgtccttg acagctagtg
    48721 gtattcctga catcacattg tcaggatcaa tccccttagc atcaagtgca gcagcctgct
    48781 ttaaagcagc ctcgcaagca atggtaatga aagaacccac agcctcctca cgcgccttga
    48841 tatcctcaag ggttgccttt gttagctcaa ctgcagaaat gtcctttgca acaagaagct
    48901 catgtaattc ttctatagta tgatgattaa aagacattag gcatctcctc cgtcatcaag
    48961 aatagctggt accttgatga aatgattttc tttttcagga acattttgaa acaggagctt
    49021 gcgatccact ccagcctcag cgatatcagc tcgcatgata tttttcttgt ctgccattgt
    49081 ggtggtaatg gcaacacctg tcgtatccac ttcatttagc aattcaacca tgtcaacgat
    49141 ttttgataat gttgtcgcaa actcagttgt ttcactttct gaaaaggata gctttgatag
    49201 ggccgcaacg tggcgaacct cttcttcaga aattttcatg aattctccta tccaaggtaa
    49261 agcagaccat catcagccac aaggccttgc tgtttcaaac gcttgataat agcctgaata
    49321 acccaatttt acatagtctt aaccattata tcataattag ctttatttac catagcggac
    49381 tgctgggatt tcacgtcaaa tgcatgtggc aactgacgtt ttctgataac gtttttcata
    49441 agctcaacct gcttttttca agaacagcca ggctataact aaactgcatt tgagcaattg
    49501 atgaggttaa aagggcaatg tggctagagc atagctacct gcattttatt cacgtgtatg
    49561 cgtagctggg attagcgaaa aacttaataa caaaaagcct cctagccaag accaaaagat
    49621 ctcactaaga agcccttaag atcagcgctg agccaagcag cagctaatac tgccttactt
    49681 gattagccta tcccagctga tcgaacgatc gcctaagaaa gccgatcaag aagctttgct
    49741 cctaggacag tcctacagtg gttcagcgcc cactggtgat tttctgttga attgctcgcc
    49801 actgctgatg tgataatctc aagcttgtag cccaatttat aggcatcaat cgctgtatga
    49861 aggacacaaa tatccgtcag cacacctgtc aagaccagcg tcgtgacgcc acgctcacga
    49921 agacgaatat ccaaatcagt ccccgaaaag gcagaataat gccgcttatc cagccaaaag
    49981 acccgctgat cttgctggta tctggtatat acggtcatca aaggaccata caggtcccga
    50041 ccccttgtcc cgataatatt atgcggcgga aacaaggctg cctccggatg aaagctatct
    50101 ccctcctcgt gggcatcaat cgcaaaaaag atatagtagc cggcctcaaa ggcagcctca
    50161 acaacgctag ccatcgcctc tgaaatcacc tgagcaggtg ctcctgccgt caggctacca
    50221 tcatcagcta caaagtcatt cgtgtaatca atagaaatca aggccttcac agcttatccc
    50281 tccccaaaaa gcttatgctc tcttagctgc atgacagcaa gccataagaa ctaagcctgc
    50341 ttttaatatt cagtatgatt agacacttat agtttaccac taaacacgac agctgtcaag
    50401 acagcggatt gatttataca cgataaaggc gaaaaacagt tatttctgaa ctatagtata
    50461 gatttaagta gacactttca acgtttttct atatgaaaat aagatatatt cctgaaatag
    50521 ctgaacattg aaatacagaa agccttattt tcttgctaaa aatctttcat gcatctgtca
    50581 tgttcatctc atgctgaatc acagcgaaaa tacaaaaaat acccctcaaa agccagccaa
    50641 tgctagaacc tttgagggga cgctataata atgtgtgaag tcctccacag ctgctaagaa
    50701 actccgataa gccgtcataa agaccaagtc tagcccttac caagcagggc tctggctaat
    50761 gaatggctgc tctataagca gcaagacttt gatcatagct aacactttca ctacctgctc
    50821 tgactaatca cagctagcaa agctaaaggc aagccttggg cttagcagac gatcgcatct
    50881 gagctattaa aattccttta gcttgtcaaa gatgccttcg ttaatcacct tgagataagt
    50941 gcctttcatt cctagagagc gactctcaat gatacctgca ctctctagct ttctaagggc
    51001 attcacgatg acagatcgtg tgattccaat acgatctgca atcactgaag cggtcaggcg
    51061 tccttcattg ccatctagct cactaaggat agctgcaaca gccttcattt cagagtaaga
    51121 tagagtgttg attgccatat taacaactgt ctgcttacga atggtttctt ctaggttttc
    51181 tgtttgaaga tttaacagct gaataccgac cacagtgctt gagatttcaa ctaaaacaag
    51241 gtcatcatca ctgaattcat tgtcgttacg ccagatgatc aaggtaccta agcgcatgcc
    51301 gccaccatag ataggggcaa tcgtggttaa accatcagga tagatatcct ttgactcaat
    51361 aggaaaaatc gttagttcat tttccacaga aaggtttgct tcagtgtcat aaacacgact
    51421 agctgccttg acataagcat ctgggaactg tcttgtttca aaaaattcct cgacgcggtc
    51481 tgtgttggtc ttgtacttca tcgcatagcc aagtaagctg ccgccaccat tgatgataca
    51541 agcattacaa tcaataatat ctgctaagcg tgaagccata gtgttatagg ggagttctgt
    51601 ttccaagctg tctacagaac gttgcaaaat agaagtaatc ttacgggttt tttctaataa
    51661 atttggcatt ttttcttttc cttttaatta tttgcgttac aattatatca aaggacccta
    51721 gcttttgcaa ggaattatca gaaaattggc tattatacct acaattcgga tgaggccaga
    51781 gccttatttt gctgaaaaac aaaaaggatc tcgcgatcca atttttgtat gagaatcata
    51841 ttagcgcttg tattgcttga gaacatgcgt gatcttttct tgcacgtcag ctagctcttc
    51901 tactgttggc agatagacca cgcgaaaatg atcaggctcc ttccagttga agccacgccc
    51961 atgtaccagc atgacctttt cttgcttcaa aagctgtagg acaaattcct cgtcgtcatc
    52021 aatgcggtac atatttcgat caattttcgg aaacaaatag aggcctgcct taggctttac
    52081 agctgatagg cctggaatgg cattaatggc ctggtaaatg aagttacgtt gctcaaagat
    52141 gcgaccaccc ggaagcaaga gctcatcaac agactgacgt cctcctaagg aggtctgcac
    52201 cacctgctgc gctaagacat tggagcacaa gcgcatgttt gccagcatgt tcaagccttc
    52261 aatgtaacct ctgacatgtc ttttagggcc tgacaagacc atccagccca ctcgaaagcc
    52321 ggcaatacgg tgtgattttg acagcccatt cattgacacg caaaaaacat caggtgcaag
    52381 gctggcaatt gcgatatgct ccccaccgtc catgaccaaa cgatcataaa tctcatctgc
    52441 aaaaatgata agctgatgct ctctggcaat tgcaacaatc tcctctaaga cctctcgagg
    52501 gtagagagca cctgttgggt tattgggatt gataatgacg atagcttttg tgcgctcagt
    52561 gatcttggct tttatgtcag caatatcagg ataccattca gcctcttcat cacacaggta
    52621 atgcaccgca tgcccaccac ctaggctgac acaggctgtc caaaggggat agtcaggcat
    52681 tggcaccagc acctcatcac cattatcgag caaggcttga agagacatcg aaatcagctc
    52741 tgagacacca tttcccaaat aaatatcatc aatgtcaaca tcaggaaagc cctttagctg
    52801 acaatattgc atgatggcct tacgagctga aaaaatcccc ttgctatcag aatagccctc
    52861 gctggagcga gcattgagaa tcaaatcacg aataacctca tctggagcct caaagccaaa
    52921 ggctgctggg ttacctgtat ttaatcgaag gatcttttca ccattagcta tcatacgatt
    52981 agcctcgtcc aggactggac ctcgaatatc gtaggctacg tgttctaatt ttgatgattt
    53041 ttcaattatt ttcatagtct cattacctcg taacccatat tataaaccaa aacaattaaa
    53101 atagaaagca cttttctatg agcttaaaga atgccaaaag ctcaaccaaa gctctaagca
    53161 agctaagcag cagctattaa taaggctatc taagctagct tctagctcaa ggtatcctca
    53221 cctcagggaa tagctgggct atttggtgaa caatagctca gaaaatcatt aaaacgtttt
    53281 caatttctcc tcaaaaaagg tataatagct atagagataa agttcaaagg aggataaacc
    53341 gatgtcacaa acatatgaac gtatcatggt cgctattgat ggctctcatg gctccgaatt
    53401 agcctttcac aagggggtta atgtcgcttt gcgtaatggt gctgccttga ttttgaccca
    53461 tgttgttgat acacgtgcgc tgcaaagcgt tgcaaccttt gatagctaca tttatgacaa
    53521 gttggagcag ga
//
LOCUS       DARYXZ010000006        53416 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYXZ010000006 DARYXZ010000000
VERSION     DARYXZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53416
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            3..2189
                     /locus_tag="TV186_000288"
     CDS             3..2189
                     /locus_tag="TV186_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1531721.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
     gene            complement(2301..3020)
                     /locus_tag="TV186_000289"
     CDS             complement(2301..3020)
                     /locus_tag="TV186_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1531722.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
     gene            complement(3626..3985)
                     /gene="rplT"
                     /locus_tag="TV186_000290"
     CDS             complement(3626..3985)
                     /gene="rplT"
                     /locus_tag="TV186_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL1531723.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(4046..4243)
                     /gene="rpmI"
                     /locus_tag="TV186_000291"
     CDS             complement(4046..4243)
                     /gene="rpmI"
                     /locus_tag="TV186_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL1531724.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(4283..4813)
                     /gene="infC"
                     /locus_tag="TV186_000292"
     CDS             complement(4283..4813)
                     /gene="infC"
                     /locus_tag="TV186_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL1531725.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(4828..4950)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4974..5654)
                     /locus_tag="TV186_000293"
     CDS             complement(4974..5654)
                     /locus_tag="TV186_000293"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL1531726.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(5669..6166)
                     /locus_tag="TV186_000294"
     CDS             complement(5669..6166)
                     /locus_tag="TV186_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL1531727.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            6215..6412
                     /locus_tag="TV186_000295"
     CDS             6215..6412
                     /locus_tag="TV186_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL1531728.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(6399..6887)
                     /locus_tag="TV186_000296"
     CDS             complement(6399..6887)
                     /locus_tag="TV186_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL1531729.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(6932..8155)
                     /gene="pepT"
                     /locus_tag="TV186_000297"
     CDS             complement(6932..8155)
                     /gene="pepT"
                     /locus_tag="TV186_000297"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL1531730.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(8325..9344)
                     /gene="galE"
                     /locus_tag="TV186_000298"
     CDS             complement(8325..9344)
                     /gene="galE"
                     /locus_tag="TV186_000298"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1531731.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(9412..11781)
                     /locus_tag="TV186_000299"
     CDS             complement(9412..11781)
                     /locus_tag="TV186_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1531732.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(11861..13024)
                     /locus_tag="TV186_000300"
     CDS             complement(11861..13024)
                     /locus_tag="TV186_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1531733.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(13038..14522)
                     /locus_tag="TV186_000301"
     CDS             complement(13038..14522)
                     /locus_tag="TV186_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL1531734.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(14526..15767)
                     /locus_tag="TV186_000302"
     CDS             complement(14526..15767)
                     /locus_tag="TV186_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL1531735.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDKKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(15751..16107)
                     /locus_tag="TV186_000303"
     CDS             complement(15751..16107)
                     /locus_tag="TV186_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL1531736.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(16112..16801)
                     /locus_tag="TV186_000304"
     CDS             complement(16112..16801)
                     /locus_tag="TV186_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1531737.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(16831..18576)
                     /locus_tag="TV186_000305"
     CDS             complement(16831..18576)
                     /locus_tag="TV186_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL1531738.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(18573..19580)
                     /locus_tag="TV186_000306"
     CDS             complement(18573..19580)
                     /locus_tag="TV186_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1531739.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(19601..20809)
                     /locus_tag="TV186_000307"
     CDS             complement(19601..20809)
                     /locus_tag="TV186_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1531740.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(20809..21612)
                     /locus_tag="TV186_000308"
     CDS             complement(20809..21612)
                     /locus_tag="TV186_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531741.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(21612..22547)
                     /locus_tag="TV186_000309"
     CDS             complement(21612..22547)
                     /locus_tag="TV186_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1531742.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(22537..23691)
                     /locus_tag="TV186_000310"
     CDS             complement(22537..23691)
                     /locus_tag="TV186_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL1531743.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(23816..24664)
                     /gene="rfbD"
                     /locus_tag="TV186_000311"
     CDS             complement(23816..24664)
                     /gene="rfbD"
                     /locus_tag="TV186_000311"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL1531744.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(24806..25144)
                     /locus_tag="TV186_000312"
     CDS             complement(24806..25144)
                     /locus_tag="TV186_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL1531745.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(25442..26551)
                     /gene="rpoD"
                     /locus_tag="TV186_000313"
     CDS             complement(25442..26551)
                     /gene="rpoD"
                     /locus_tag="TV186_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL1531746.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(26560..28374)
                     /gene="dnaG"
                     /locus_tag="TV186_000314"
     CDS             complement(26560..28374)
                     /gene="dnaG"
                     /locus_tag="TV186_000314"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1531747.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            28621..28995
                     /gene="mscL"
                     /locus_tag="TV186_000315"
     CDS             28621..28995
                     /gene="mscL"
                     /locus_tag="TV186_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL1531748.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(29221..29397)
                     /locus_tag="TV186_000316"
     CDS             complement(29221..29397)
                     /locus_tag="TV186_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL1531749.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(29552..30364)
                     /locus_tag="TV186_000317"
     CDS             complement(29552..30364)
                     /locus_tag="TV186_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1531750.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(30432..31547)
                     /locus_tag="TV186_000318"
     CDS             complement(30432..31547)
                     /locus_tag="TV186_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL1531751.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(31817..35458)
                     /gene="addA"
                     /locus_tag="TV186_000319"
     CDS             complement(31817..35458)
                     /gene="addA"
                     /locus_tag="TV186_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL1531752.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(35448..38669)
                     /gene="rexB"
                     /locus_tag="TV186_000320"
     CDS             complement(35448..38669)
                     /gene="rexB"
                     /locus_tag="TV186_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL1531753.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(38878..40278)
                     /locus_tag="TV186_000321"
     CDS             complement(38878..40278)
                     /locus_tag="TV186_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1531754.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(40420..42561)
                     /locus_tag="TV186_000322"
     CDS             complement(40420..42561)
                     /locus_tag="TV186_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531755.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(42568..44001)
                     /locus_tag="TV186_000323"
     CDS             complement(42568..44001)
                     /locus_tag="TV186_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL1531756.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(44007..44684)
                     /locus_tag="TV186_000324"
     CDS             complement(44007..44684)
                     /locus_tag="TV186_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL1531757.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(44698..45393)
                     /locus_tag="TV186_000325"
     CDS             complement(44698..45393)
                     /locus_tag="TV186_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL1531758.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(45521..46156)
                     /locus_tag="TV186_000326"
     CDS             complement(45521..46156)
                     /locus_tag="TV186_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL1531759.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(46146..46685)
                     /locus_tag="TV186_000327"
     CDS             complement(46146..46685)
                     /locus_tag="TV186_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL1531760.1"
                     /translation="MVKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(46974..50690)
                     /locus_tag="TV186_000328"
     CDS             complement(46974..50690)
                     /locus_tag="TV186_000328"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL1531761.1"
                     /translation="MMKRLRENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            51170..51715
                     /locus_tag="TV186_000329"
                     /pseudo
     CDS             51170..51715
                     /locus_tag="TV186_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            51796..52251
                     /locus_tag="TV186_000330"
     CDS             51796..52251
                     /locus_tag="TV186_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531762.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            52251..52538
                     /locus_tag="TV186_000331"
     CDS             52251..52538
                     /locus_tag="TV186_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531763.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            52531..53079
                     /locus_tag="TV186_000332"
     CDS             52531..53079
                     /locus_tag="TV186_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL1531764.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(53258..>53416)
                     /locus_tag="TV186_000333"
     CDS             complement(53258..>53416)
                     /locus_tag="TV186_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1531765.1"
                     /translation="EAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAV
                     VSRKRKKH"
BASE COUNT        15860 a        12193 c        10106 g        15257 t
ORIGIN      
        1 ctgtgaagaa ttttaaaaca tttatcacaa gctttatcaa tacaagatta ggctttgtgc
       61 taacgcttct cttctgcttt tggataaaaa ccctatgggc ttaccatgct gacttttcac
      121 tagatttggg aaatgcctat caggtctttc taacaattat taacccaatc cctctagctt
      181 tgttactatt gggatttacc ctttatatca agaatactag ggccttttat atcagctctt
      241 ggatcgtcta tattatcctt aacctcttgt taatatcaaa ttctatttat taccgagagt
      301 tttcagattt cattacggtt agtgctatgc tagccagtag taaggtttct gctggtttag
      361 gagactctgc tttaaacctt ttgcgcattt gggatattgt ttacgtcctt gatttcatca
      421 ttctgattag tttatcagta actaagacca tcaaaaaaga cccgcgtcct tttaacaagc
      481 gggcttcctt tgctgttaca gcactgtctt gcttgctctt atctgttaat ctgtttcttg
      541 cagagattga ccgcccggag cttctgacta gaggattttc aaatacctat atcgttagag
      601 cgcttggatt gcctgctttt accatttaca gcggaaacca gacctatcaa gcacaaaaag
      661 agcgtaacgg agcaaccgct gaagaattag tcgatgttaa gcaatatgtc aagaaccact
      721 acgccgcacc tgatcctcaa tattttggaa tcggtaaggg aaaaaatgtc attgtgatcc
      781 acttggaaag cttccaacaa tttcttattg attacaagct caaggatgac gacaaggact
      841 atgaggtcac accttttatt aattccctct accactccaa tgccacacta gccttctcta
      901 actttttcca tcaggtcaag gctggaaaaa cgtctgatgc agagaccatg atggaaaatt
      961 cattatttgg cttaaacagt ggttctttta tggtaaatta tggcggcgaa aacacacaat
     1021 tcgccacacc atcaatccta gcacaaaatg gcggctatac tagtgccgtc tttcatggga
     1081 atgtaggaac cttctggaat cgcaataatg cttataagca atggggctat cattactttt
     1141 ttgattcaag ctatttttca aaacagactg ataaaaactc tttccagtat ggcctaaatg
     1201 acaaatacat gtttagagat tctatcaagt accttgaaca gcttcaacaa cccttctaca
     1261 ctaagtttat taccgtcagc aaccactacc cttacaccag ccttagaggc gaaagcagtg
     1321 aagagggctt tccactagcc aaaaccgatg atgaaaccat caatggttac tttgctacag
     1381 ctaactatct ggattcagcc ttgaaatcat tttttgatta tctcaaggcg acaggacttt
     1441 atgacaattc tatctttgtt ctatatggtg accactatgg tatttctaat tccagaaatg
     1501 tcagcttggc agaattacta ggtaaagacc ctgaaacttg gtccgaatat gacaatgcaa
     1561 tgctccagcg tgtaccatat atgatccata ttccaggcta taccaatggc gggatcaaag
     1621 aaacctttgg cggagaaatt gattccttac caaccttact gcatatcttg ggcattgata
     1681 ccagcaagat ggttcaacta ggacaggatc tcttgtcgcc acaaaatagt caaatggtag
     1741 cacaaagaac ctctggaact tatatcacgc cagactacac tagctatagc ggtcgccttt
     1801 acaacactca aacaggcttg gaaattacaa accctgatga gatgacaatg gctaaggtca
     1861 aagaaatacg agcagccgtt gctcagcagc tagcagctag tgacgctatc caaacaggag
     1921 acctactacg ctttgatacc gataatggtc tgaaacctgt tgacccaaca accttcattt
     1981 ataccaagca gctaaaacaa ctcaaagaga tatcagagaa attaggatca cattcaacca
     2041 gcatttatag taaaaatggc aacaaatcaa ctcaaaagct ctttaaagca ccttcttatc
     2101 tggagttaaa tcctaaagaa gccgaaaaac ctgaatctac ttcgtcttct gaccctaaag
     2161 aagaatccgt taaggaacaa agtcagtagt ggatgtctaa agcaagcctc actaggatcg
     2221 ctctcgtaga agactaaaag caagctaaaa gccttcattg agcgttacaa cttaatgagg
     2281 gctttttagt tctgacactt ttattgagga atggcctcaa agtattctgg atctggtgtc
     2341 ggttcaggtg ttggcacagg atctagctta ggctcaggct tcggttctgg tgttggcaca
     2401 ggatctggct taggttcggg tgtcggtgct gggctatttt cttgcgtcac aatataaccc
     2461 acataacagt aatcatcaac cttttcttct ggagtgtaag taaagcttac ccccttaacc
     2521 gtagtcttag tgacgatatc attgagatga cgtaccacat caactgcact aacagctgtt
     2581 gtcgcaccac cagctaccaa caaggcaatc aacacatagc taccgctttt cctatttttg
     2641 taaataagat agcctgaaac acttagtaag cctagcccta ctgccaaacc aaccagacca
     2701 tctgctgcac cacccgtttt aggcaagacc ttagcgttag ccttaggggt agacatcatt
     2761 ccttttggag atgctgtcac tccacagctt ttgtcgtaaa caagaacgta atgcaattta
     2821 tcttggatag gtacttcatt tggagtgcct ttttgaatgc ctgctttttg ttcatttgtc
     2881 agattagaat aggctgtata ggtcaaatct accgttaccg tatcagcatt agtgttggca
     2941 ttgacattag ctgctagcaa agatagacct aacatcgttg tagctcccat gtattgaaac
     3001 gctttagaaa aacgtggcat tataactatt ctccttaatg ttttgtagaa taaaaccaat
     3061 aactaaaaag gcatctccta tcatatcaat cttatgatta ttataggtaa atgtgatttt
     3121 tgtaagcact atctaaaaat ttcaaataca ctcatatcaa tagatattga ccaaatctca
     3181 gcagctttaa gcatatcata acaataaatc accttattga cacaaataga aaggacacat
     3241 ttatacttat cattttcatt ctattatatt aaaccatatc ttgtgttaaa atacaatgaa
     3301 attatgacat tatggctcct aaataagttg ttttgcattt tattattttg gtgatggatt
     3361 tgattaaaac tagaaatcat atatctcctt atatgatcat cacttgatgg actgctcaac
     3421 tgtctgatac aagattaagc cctttcttct tagttaacag ctaccaaaga aaggtaaatt
     3481 ggctccttta tactaaatta gagatagcta aaaacatctc aaatactctt gacaaaacgt
     3541 catgactgtc ttatctagct agattagcta acataaggca ttaaaaatag acttagaagg
     3601 tttctaagtc tacagtcgat ctctattatt tgccaagctt tgccttagca gcatcagcaa
     3661 gggctgtaaa agctgctgca tcattcaccg ctaaatcagc aagcatttta cggttaactt
     3721 cgatttcagc aagctttagg ccatgcatca attgtgaata tgacaagcca ttcatacgag
     3781 cagctgcatt gatacgtgtg atccatagct tacggaagtc acgttttttc tgacgacggt
     3841 cacgataagc atagtaataa gaattcatga cctgctcttt tgcagtacgg aacaagatat
     3901 gttttgctcc ataataacct ttagctaatt tcaaaatacg tttacgacgt ttgcgtgata
     3961 caacgccacc tttaacacgt gccattaata ttctccttca aataactctt ataattctag
     4021 taaatacctg ttacaaccct taatcttaaa ggccagtaac cattgcttta atacgcttga
     4081 aatctcctgc atgcaccata cctgctttac gaagatgacg gcgttgcttt ttagtctttc
     4141 catggaaacg gtgtgatgta aaggcacgga agcgtttcaa accgcctgaa cctgtacgtt
     4201 taaaacgttt agctgatgcg cggtgtgttt tttgttttgg cattttaata ttctcctctt
     4261 aacatatagt gtaatatgac aattacttct tgtctgaaat tggtgcaagc tgcataaaca
     4321 tttggcgacc atccattttt gctctttgct caataatagc aatatcttga gttgcctcag
     4381 caaaatcagc cagtacctta gcaccaatct ccttgtgagt aatcatacgt cctttaaaac
     4441 ggatagaaac cttaacctta tttccctttt caaggaactt acgaccatta cgaagctttg
     4501 tttcaaagtc acccttgtcg ataactgggc taagacgtac ttcctttaca gttacaacgc
     4561 tttgcttttt gcgttgctcc ttttgctttt tttgatactc aaatttgaac tttccatagt
     4621 ccataagctt ggcaacagga ggaacagctt gcggctggat taaaaccaaa tctacatttg
     4681 cagcatcagc taaagactga gcttcagata atggtttaat gcctaattgt tcaccttcaa
     4741 gaccaacgag acgaacttcg cgaacacgaa tctcatcatt aatgaataga tcttttttag
     4801 ctatgatctt cacctcttta tttttttaga gaaaaacgaa agcggactta atgaaccaag
     4861 cccgcacaca taatatcccg taggaatttg acatgtaggg ccagacaacc taggtcgcaa
     4921 ggcgagaagc tctcacttct gcttttctca ttattgacat tctaacaaat aaatcatgcc
     4981 atgtcaatta ttttttctgc tttttcctga ataaattgga caacagctga aatcgtgata
     5041 ccggtagtat caaagataat cgcgtcatct gccgccttta gcggcgaaac ttgacgatga
     5101 ctgtccttat aatcgcgtgc cgcaatctca gcctttaagg tgtcaaaatc agctgcaatc
     5161 cctttttcaa tattttcctg ataacgacgc tgcgctcttt cttcaacaga agcaatcaaa
     5221 aagatcttca actcggcatc aggcagcaca accgttccga tatcacgacc gtccatgata
     5281 atagcaccag tcctagcaat tcgtcgctgc tgattcacca gctcctctct aatctctggc
     5341 aaggcggaca cccaagaaac attattggtg acatcatttt gcctgatcgc cattgtcaca
     5401 tcttggtctc caagaaaaac cagttgtgag ccatcagctg cttttttaaa agaaattgga
     5461 cgctttgcca attcttgcag gattagattg acatcttctt tgtgataacc attttttaat
     5521 gcgatataag tcgctgagcg atacatggca ccagtatcta aataggtgta gccaagattt
     5581 ttggcaataa tcttggctac cgtacttttc ccacttgagg ctggtccatc aatcgcaatt
     5641 ctaattgctt tcatcttttc ctctttaatt atttgatatt gacctcgtca cctggattgg
     5701 cataccagta gccttgggtc atatgatctg ggtttagggc ctgtaattgc tcaacagaaa
     5761 ttccagcacg agctgcaata gatgttgctc cttctcctgc taatactgta attgtctttc
     5821 ctgctgcctc tgtagaaggt gctgtttcag tcttagaagg acttgttgtg tcactagctg
     5881 ctgagctatt agagctcgct tttggctttg tttttggttt tgagctgacc ttctttgttg
     5941 tctttttctg agttgatgcc ccgtaaaatc ctgttgtctc attttgcttg ttactaccgc
     6001 tgtttgacgt atagaagaaa ataaaaagta tggcaacaat aatgacaaag aaaacactta
     6061 acaaggcagt caaccaaggt gtgctaatga gtgctcctct tgattttctt gttcttgtcg
     6121 ccttattgtc atcaacaatt ttttcttccc atggttcttt agccatgatt cttccccctt
     6181 gttaatttaa caaaatcata ttagaataat acctatgaaa gtatctatcc ttccagaaaa
     6241 atgcattgcc tgtggtcttt gccagaccta ctctgctctt tttgactatc atgatgatgg
     6301 tatcgtcaaa ttggctcagt ctgatgagtc aagtcaactc atagatccta atgatcatga
     6361 tgccatctta gcagtaaaat cctgccctac taaagccctt accctcgagt aagaggcttt
     6421 ttttcgtatt ggtaggcttc aaaataatcc agtttaatga agttatctag taatataacc
     6481 tctcccttaa aataaggatt aatcgctaga tcatctaaaa aatatttttt aggccatttt
     6541 ctcatgtaaa aaaggtagct cttatcacca acaaatagac aaaccgttga tttagtaacc
     6601 tcaattttgg taattgaggc aatcatcagt ctgtgcggag caaatagctt taaagatacg
     6661 atcttcaaga caccattatt ctcaattaca aaataacgat gcaggccaag tcccactaat
     6721 atagcaaata aagcaaacaa gacaaaaaca cgactcggta tttctgttct ttcatacaat
     6781 aaggacaggc caataaaaat aggcgcaaca gcaattgacc aataaataat agaccaagac
     6841 agctctggct gccaatgata ccttacttta ccgaataatt taatcatgct tttccatcac
     6901 ctccaatccg ttctgagcat tttgggtgat gttaagcctt ttggacaatg ccaagaatca
     6961 catcaactgc cttttccatc gtttgcagac tcacaaattc aaacctgcca tgcatatttt
     7021 caccacctgc aaaaatattt ggcgttggaa tccccataaa ggaaatcttt gagccatcag
     7081 taccaccacg aatcggctcg ataactggct taatagctag gtcctccata acagccttag
     7141 ctagattcac aggtgtcatg tccttttcaa tcaccttttt catgttatag tactgatccg
     7201 tcactgttac aaatacacgc tctgctccaa gctgactatt catctcctca gctagctgtg
     7261 ttacaaaggc ctttctagct tcaaaggagc tatcctcaaa atcacgaata atataagagg
     7321 cctgtgcttc ttctacagta ccagacatgc tgtgtaggtg gtaaaagcct tgatagccgt
     7381 ccgttttttc aggacgatcg tcaactggta attgactatg gaaatccatt gctagctgca
     7441 gggcattaat catctgattt ttagctgtac cagggtgaac attgcgacct aacaccttga
     7501 gctctagggc tgctgcgcta aaggtttcat attgtagctc gccaagcgga cctccatcaa
     7561 tagtataggc aaagtcaaca tcaaaagcat taacatcaaa cttatctgca ccaacaccaa
     7621 tttcttcatc aggtccaaag gcaaccttaa tgtcgcaatg ctcaatctga gggttggcaa
     7681 caagaaactc aatagccgtc atgatttctg caattccaga tttatcgtca gctcctaaaa
     7741 gggttgtgcc atcagttgta atcagggtct gtcccaaata ttggttgaga tttggaaaat
     7801 cctctgggca taaagaatag cctgactgac caagcttaat ctccccaccc tggtagctct
     7861 caataatctg aggggctact ccttctgcat taaaatcagc agtatccata tgcgcaataa
     7921 aaccaatttt ccgagtcaat ttgctgctgt tagctggtaa gcttccaatg aggtagccat
     7981 tagctggatt gtaatgaatg tcctgtaggc caatagcttc catctctggc tttagcactg
     8041 ttagagcaaa gtcagcttga ctcttggtgc ttggagttgt agtgcttgct ggattgctcc
     8101 ttgtgttgat ttttacatag ttcagaaatc gttctaataa agtttcgtat gtcatagatc
     8161 acctcgataa gttttcgtta ctattatagc ataaaaggac ctaaaatact tgcctaagct
     8221 cagtttttta cagtgcttta tctgttctgt tacagttgcg ttctcataaa aagacagctg
     8281 ccaagaaagc tcttgacagc cttgattatt catcagccca tgccttaatc ctcataacca
     8341 tttgggtgct tgctttgcca tctccaagta tctgtacaca tcctttctaa gccgtactct
     8401 gcagtccagt taagctcttt tttagccttg ctagcatcag catagcaggc tgcgatgtct
     8461 ccttgacgcc ttggtaatat cttgtaagga atagacctgc caaccacctg agaaaaggct
     8521 tcgataatat ctagcacaga atagcctgta cctgttccta aattataaat agataggctt
     8581 ggctcttcag caaactttgc aagcgcagcg acgtgtcctt tagccagatc aacaacatgg
     8641 atataatctc taacgccagt gccgtccttg gtctcataat catcaccaaa aacgccaaca
     8701 caatccagct taccaacagc tacctgagaa acataaggta ataggttgtt aggtatgccc
     8761 ttaggatcct ctcctaaatc accagactca tgagctccga taggattaaa ataccttaac
     8821 aatacaatat gccactcatt atctgatgca tagaggtcct tgaaaatctc ctctagcatc
     8881 agctttgtcc taccgtaagg attggtcact gatagtggaa aggtttctaa aataggaacg
     8941 gtatgcggat ctccataaac cgttgctgag gagctaaaaa tgatcttttt acaattaaag
     9001 gctgtcatta cctttagtag ggtcaatgtg ccagagatat tattgtcgta gtaatcaagt
     9061 ggaatcctgc ttgactctcc aacagctttt agccctgcaa agtgaatgac actcacaata
     9121 ggatgcttac tgaaaatatc tgttagcagc tgttgatcgc gaatatctcc ctgataaaag
     9181 gtcacttctc ttccagctat cgaggcaaca gcagctaggc ttttaggatt tgaattgcac
     9241 aaattatcaa ccacaacaac gtcatagcca gcagctagca gttcaacaca ggtgtgtgac
     9301 ccgatatagc ctgcaccacc agtaactaaa atacttccta acattgatta tatacctgac
     9361 tttctaataa ttactaatat tataactgat tactcccaaa aagtatatct atcatttcat
     9421 tttaaagaaa tcaggatagg cattaatgta gcccttgcct tcaataagat catattctaa
     9481 cagctttaag tcagaggcca cctgcttttg agcagcagtt agctggctgt catcgctatt
     9541 tctggtatcc aagacatctg tcaaaagagc gtagtaagga gacaccttgg aatccgtatg
     9601 ctctagcaat aaagaggtaa aatcactgga attaacacga ggtctagcca atttgttggt
     9661 ctgatgattg ctccagatga aataatctgt taaatatttg acctcctcat cattcttaaa
     9721 gacctgatct ggataaaagc caggtaaatg atcaccataa aacacaactg taataggctt
     9781 gtcaaccttt tccagtgctg ataaaaaggc ctttgttgac ttgtcggtaa tgcttaataa
     9841 attcacataa ctttgcaggc tatccgtctc agactggtcc agtcctgcta ggctaacatc
     9901 aacatctctt agctctgtgt accaagggcc atgattttgc atggtaatca ctgaaaagaa
     9961 ttgacttctt ttggggttaa gctggtctaa aatattgtca taggttgact catcactata
    10021 gcttgagctc attcgtatca agtgctttgg cttgtcagct gaatcctctg tggcaatgaa
    10081 ggtatcaaat cccaatttgt tgtaaacgat ttttcgagag taattgttgg cgctcgcaag
    10141 gtgcaaaaca atcctatcct taggcgaaaa ggcattacta atggcaggcg aaaacttcaa
    10201 cttaggaaag acatcagaat acaaaatcga aactgttgga ttgaggttat attttggtag
    10261 gccaaatagg ctttgaaact ccatattagc tgtaccgccg ccatagccat cagaggtcat
    10321 taggccactc gttgtggttt ccatgatatg atggatctct gcaataggat ccttggccaa
    10381 ttgaacccca gaaatcctag ctgggtcagc aaagctctca ctcagtatat aaatcactgt
    10441 ttgatcagaa atacgctgat gcctttgctt attgatatca gcagctctag cttgatattt
    10501 ctgataaatc ttttgcatag cgctcttgct atagcctgaa ggctgattaa tggtgctggt
    10561 ggtaacctgc ttgaaccaaa caaagctcaa ggattgaaac cttgcattgg ttgtaagacc
    10621 ataccagtca atatcaaaga cattgtagac tgatgacaga actggaatac cttttttgat
    10681 ttcaccatct ttattttggc taaatacaaa aaggatagag gcaaatacca aaaggataga
    10741 gcctattgac atcagtctaa gataaagcgc tgataggatc ttttctctaa agtatctttt
    10801 atacaaaaca tagatcagca gacccgacaa gactagtatc aaaataatac taatgatttg
    10861 agtcagacta atgtaattca agaaaaactt aatctctttg atccatttca aatctgaaaa
    10921 caataaaggc tcacttcgct gcttgtattt ttcaatatta acaatactga ttaaagctcc
    10981 gatcaccgta ttgacaaata aagcaatgat atagttgtta atgagcaaaa acaccagcac
    11041 aaaaaagagg gtcaagacaa gcacctgaaa cagggttgca cctggaataa tcactgcccc
    11101 atgaaaatca ccatatgctg tgatcccagc ctgaataaag taattaaaga tgatccctaa
    11161 aaataagctg gtcactagag ctaatctaag accccatcgc ttgctcaaaa cctcgataaa
    11221 ggctgtgacg atgaggtaat aaaccacaaa cgtcagcata taagagcaaa agctatactt
    11281 aaagagattc aggctaacaa ggtttgactg actatctaaa ggccaataat cattttgctt
    11341 aatcacagtc ttaaataaag agctgttcag cgttaagact gaaaaagcct gactaagtaa
    11401 aatgacttgg attcctctgt ttgattggta gtccttctta aacaggtatt tttttaagag
    11461 aacccctaaa ataagcaggc tgactaaagc tgccagactg agtagcattt cctgaatcgt
    11521 acgattactg atggtaaacc tgctgttgtt tttattgatg gctaaggtga tatagctatt
    11581 agcaacagca tagtagctac tgacagctac agaaacaata agcagctttg aggaagcatg
    11641 cttgatcagc aaacatgcca ttccagctat taacactaag acaagccacg aaccataagc
    11701 tcccttattt aacgtgtttt tgcttaccgc aaaaatagat aaataaagag atgaaaggct
    11761 aaacaatatc atatcaagca tttctagatc aactaactgg cgagcttttg aaattatctt
    11821 cgttattata atggtcacac cctttcctaa ctgctaaaag ctagacatta ctctctgact
    11881 cagaagcgat tacctctgtt actaattgac gaacagtgac ctcccaggta aagcctgaaa
    11941 gcacctgctg atgaatggct tcttgcaggt cacaccgttt ttctttgtgc tcaatcaaat
    12001 gatccaactg ccttttaata tcagagactg tatcatcaat gatgattccc tgtgacgggc
    12061 tcgttatcac ttccttgaca ccacctctat ctgttgctaa tacagcacat ttcaacatac
    12121 ctgcctctaa tacagctgtc ggaagccctt cagcatagat ggacggatta acaaaaatat
    12181 cagattgaga cagcaaagac atggtctcag caaaattcag cttgcctgta aagatgatgg
    12241 actgatcctc tttatagcta tctcttagtg aagcaagcaa gggaccatct ccagcaacca
    12301 ccaagacagc cctgtcctta tatgtcagct gctcaaaagc ctccagcagc aaaagaatcc
    12361 ccttttcctt gatcactcga cctgcaaagg taataatgac cttatcctgc aaagctggta
    12421 aataagcctt tgacttaaag acctcataaa gatcagaatc aactgaattg tagatgacgc
    12481 ctttggcttt tattccaaag gtcttgagcc atgccatact gcgcttagac accgcataaa
    12541 agtcgggctg ataggctttg acaaaaaagg taattacatg ctcatagact ttagcaaaca
    12601 agtctagtag ctggtgacct ttaacatttt cgcccacctg aacatagcca ccaccatgct
    12661 cgatcacaat actagggatg gcttttcttt tggctagctt caagcccatg aggcttgtca
    12721 aataaaatcg tgtattgcag atcacaaagt caatacgttc ttccatcagc tccgccagca
    12781 tgctatgata cagatcattc ttatctaaaa tcggatagcg ctgcttaaat agctgctttg
    12841 aaggaaatcg gtaataagta atggcttgat ctctttcaat agggctcagc tggtggctgt
    12901 tgctggttac aatgatgata cggtagccta ggctcactaa ttgttgcgct attttttctg
    12961 tataccgctc tactcctcct agatgagggc ttgtaaagcc gctaaaaatg gctattgttt
    13021 tcaaagcttt tcccttctta tgtataatat tgcagcattg ttcgagtaat catacctagg
    13081 atcaatagca acgagccaat aagaacctgt ttattactta ataggccttg ggccttttca
    13141 aggtatttgt tattagaggc cagcaagacc aacactaaag ggatcacacc caaaaagtac
    13201 ctatcttgaa cccctagcac attaaggtct ccaactggcg taaaggtcaa ataaaggcta
    13261 aaggtaatac cgcctattat tcctaaagac atcaatccca taccaaagcg agataaggtc
    13321 ggcagctgaa gcttgttggc attagtgatg acaacagcaa aataataaac catactaatt
    13381 ggcatgagct ctaccatacc gtatgataaa gggccaaaca tgtaaatccc tgaaggatta
    13441 aggatatgag ccaacgtgtg tcttagcagc ataaagccat atactatagg gttccttaac
    13501 acagtcagta gctgctcttt agcattgacc ttctggagaa agtcagccat atccacctga
    13561 ggtgacttga tttgaccata tacctttaac caaaaaacag tcacaaccag caccgtcaga
    13621 attgacaaca gctttagcag aaacgtgcga gaggcttttg ctccaaattg acgtgaaggg
    13681 ataaaaagca gcaacaaaat caataaaata taaggcagct tagtaaaggt aatgattgag
    13741 cacagcaggg tataccaaaa gagcttggat aagggaatct tttcagttgt agccatctga
    13801 acaaataaag aaatcgtcag aataatcaat ccaatagaga cacaatcctg attataagaa
    13861 ccagcaagat agatattcat cggaaggaga cttcctacag caagcagctg cttgcctgct
    13921 gtcagcaatc gtaaggcaac aaaaaccaag atggcatagg caagaacatt acaaagccta
    13981 cctaaaaggt aagataagcc catggtcaag cctaagctcc ttccaataaa taagcctatt
    14041 acctgtggta tgtaggcaaa gttataatag ccatttgttg agcgaatttc cttaaatgaa
    14101 atagcctcat ctgtatggtc tctgctccac agctgaaagc gtaagggctt gccattgttg
    14161 tggtccataa gattaatgtc atcagtcacc agcagctttg agtcatcatt ggttaaatta
    14221 agatttccct cagataagta taaggctctt gcaaagtgaa ccctctcatc aggaatatca
    14281 ttgatcggtg agatgaaggc agagacagaa cccataacca caataataag cactgtcgca
    14341 tattccatat ttgaaggtaa aaagataatc aaaagcgcag caattgcaac taatattgct
    14401 aaaaatttaa tgggtaaatc cgttgattgc gtatataaaa gcagcaacac aagaaaggca
    14461 ccaagtaaaa caagcaaagc cttactcgcc ttttgcaatt tgtcaaataa ggtatctaac
    14521 atatcctatt tccttttttc cataatgtac aagccatatg acaatagcag ccaaatcatc
    14581 attgaaatta taaaaccata ggtaactcca atcaccccaa agcttctagc caaagaacca
    14641 gtgatggcta gtgaggagat aaaggataca acataaggta tcacaagcaa gtgctgcttt
    14701 ctgataatgg taatcaaatt atcaatataa gtggcaaagg tgctgataat ccctccaaaa
    14761 ataagaagca taaaatcaag ctggtaatgc cttaaatcaa taccataaac aagcgatagc
    14821 accggcagcc ccacaaaata gctagcaagc aagatagcta ggcttgctaa tagcagcact
    14881 agactgagac gacgctctaa ttgtgcaaag ctcttcttgt cctcttttga atggtaaatg
    14941 gccagctgag tgatcatagg ccttaaaaac aagaaaatca ggttaatcat aaaaataggc
    15001 ataaacaaaa tattaaattc tgtttgaaca ccggctggga tcagctgctt tgagtaaagc
    15061 tgctccaaaa caaacttggg ctggttgtag atataaatga gtaaaaaacc atttaaaaag
    15121 aggggaaagc tctccttcaa tagccctaag atgctttgag catcaatacg acgctcaagg
    15181 ctcgtaaagg aaactgaagg ggttatgtca aatagcacaa tacaagccac tgaaataaga
    15241 catatcacga tcaaagacag gactagctgc ttggtcagaa ccagacagag cgtaaagcca
    15301 agaatcacca gcatatttcg ataaaacaag gatttgccgg caatatctaa gcgctctctt
    15361 tgttgaaaca ttccttgaaa cacatcagaa atggcatctg tgcaacgata caagcaaatc
    15421 aaccaaatca ctagcccctt aaacccacta tagctcccca aataaatata gagcactgaa
    15481 atggctatca tcaagaaaca ggtgactagt cttgtataaa aatagtcttt gaagcggtac
    15541 ttgtgtaata tatccgttga ttggaaattt ctaatctgaa ataagccaat agtaatcagc
    15601 tgatttccaa tagcataggc aaagctaaag gtatctgaag ctgatttaga taagacccga
    15661 gacacaatca tcagtaaaat cactgatatt agtgctgtcg agctggttcc caacacattc
    15721 caaataaaaa tcgactgatc cgattgaatc ctactgctgg ttttcatctt cttcctgctt
    15781 ttccttctca ttaagggcta aatactgaat cattttttta agcttaatct ctgtccgaga
    15841 caatttttga gtgataaaaa attggttgat gatgagtaaa aaaatgattg atagaaaaac
    15901 aaaatttgcc ggcgattcaa agcctagcag ccttgaaaaa taaaccgcag catttggaaa
    15961 cagtgacagc aaaagcacta ttaaagagaa aaagagccaa aaaaagctat cttcaattaa
    16021 aattttggat ctgcgaatgc tatctagtat aaacatggct gtcaataatg caacaatgat
    16081 caaaatcagc tgtaacccaa taaacatcct cttacctctt tctaaagttt tgaattaaaa
    16141 taatcgaaat aaacatgtga accatgtatt taatagatct agaaagagtg aggtagcttt
    16201 gaccagccag cctatcattc atttgcacct gaacctcact caccctatag ccttgtcgaa
    16261 taagataaga gatcgtatca ggctctggag tatagttaat attagttgca aaaatcctga
    16321 tcagctcctg attaaacatt ctcataccag aggtcggatc ggtaatacgc tttcctgtgg
    16381 ttagcttgat aaaaaagcta ataaggctat tgcctatcat tctcaaggat ctattctttt
    16441 cagcactgac aaaccttgat ccaatgacac aatcagcacc agcattaatt gaatcgctca
    16501 aagcctcaat atactctggc aagtgttgac catctgcatc gaactggagt gctttagcat
    16561 atcccttttt aaaggcatat ttaaagcccg tctgaatagc accagataag ccaagatttt
    16621 ccggcaaatc aatgatattg taatggttat gatgacagat ctctgatgtc cgatccgaag
    16681 agccatcatt gataatcaca taatcatatt gaggaaaatg tcttttgata ttttccacta
    16741 ctttttcaat cgactcctct tcgttatatg ctggaatcat taccaataag tcttttttca
    16801 tatcgtcaaa tattctctct attcattcgt ctaaacgcgt ctttttagca atcgctttat
    16861 gatataacgg atagccttag ctggcccaat cacaatatat tttaaggctc cttttatacc
    16921 tcccatatag tcaaaatcga cataggtatg tggcacactg ccttcacgca ggtttaagag
    16981 cttattatca ataaatggtg tcaatagctt ttcatttctt gaaattctaa aatcatagtg
    17041 tctgtcccaa gcaatataaa ttaagagacg ttcaatggca tgcaggatcg aattttgaga
    17101 cagaggctct gctggaatat cagcctcact taggtctaag tcaaacaagg gctttaaggc
    17161 atcgtattta aaccaaacaa aggtgccata gctcatgaca aaggtatcca tcgtctgaaa
    17221 atcaatgcgt tttgtaagcc ccattgcctg ccaaagctga ttcatttcag gggcaataag
    17281 gtgctcattc caagcgtcaa caattttatt aaaacggaaa aaacttggaa tatctgctat
    17341 cacaataccg atagcatcag cagccagtgc tgttaggatt tgatccgccg gcttcaccat
    17401 catatcaatc aattcagtgc gccaggattg gcccgcccaa aaatctgctt cctttgattt
    17461 tttggtatga aaatgcccaa tataatcata ttgagacaat cgttccttta aggtcagcat
    17521 tggcaagaca tctcgaccga tatttcctgt caccaatatg tcagcacttg ccccgctttc
    17581 tcgtagaatt tctttaatct cagccttttt agccttgcta tcggtcgtta tgagcaagtc
    17641 ataatcaaaa tgaaaatgac taaatgcttc taaaaactct gacaataaat caacataaaa
    17701 aacatgaaga tgaacagcaa ttttcttgct ttgatcaatg cttatcggct gctctggcag
    17761 gtatttatgt gccagaagat acttagcatc tggtggatgg acctgcgaca tatgatccac
    17821 aatcaagctg gcagggtatg tcgttttttg gtcaataaaa tccaaaaggt aaggagcaat
    17881 gtgctggtta gcgtcaatag ccttaacctt gataaagggc acatggtgct ttaagatggc
    17941 tgtcggattg taataagaga aatccgcatg cagcatagag gacgagtcct ccttggtcgt
    18001 atcaaatacc gtcttgtatc gaaagccagc ctccacaaag acagtggtta ttctggtttc
    18061 ataattgtgg atcacatctt gaacgtctgt tagctcaacg atattttccc aaaactgcct
    18121 aaattcctta ctatgaacga gggatttttt gaagctgata aaatagctct gaatatgctc
    18181 tttaaaggcc ttggtcgctc gattgttggt catgccccag aaatcaactg cttcatctgc
    18241 ttcatatttg agataataag gcttcatatc ccaaagcgga ccaaagcagg tatcgttcat
    18301 aatcgtgatt gagtcaaagt caacaaggtg ctcacagcct aaggccttca taccatcatg
    18361 ccaagctgca aaatcatagc ctttattgtg tcgttgaata aactgatcca tcaaatgccg
    18421 ctgttcaagc tgctcaaggt cctcttgatg gatatcacta tttgaaataa agacaatctt
    18481 tgaaaacaag gctctcatct gttcgagctg gtaataaaca tgatcgctta ccttatgata
    18541 tttattgaaa tgcacataca ataatagacg cttcattttt tcctcctaaa aagctcaagc
    18601 agctttgata ggtacctcca acgacgtgag gtaaccacac aattgtattg atgggttagc
    18661 gcttcaacct cttgcctttg atgatcaagc tgctgctgta gctgatctat cttctctgcc
    18721 tgtagagcct cctgatctgc aagcgtctgt cgtaattgat gaatggtatg acttaattga
    18781 tgaatccgaa tttcattttt agcgtcctgc tttagtaatg cttttgcaat agcttccata
    18841 ttggctgtag ggtatttaga caaataggac agctgggtct ccaacaagcc ttgaatacgg
    18901 cccagcattt tttcctctgc tgccggcctt gaatctgaat tatccgtcat tcgataaaca
    18961 gtggtcgaat ccttcaaata ggctagagag gttgactgaa acagctctaa ttgtatgtca
    19021 aaagtgtcgt ctgacgtctc caaatcaatg cgttgattaa ctgccctcat cagatcagcc
    19081 tccaccagcc aggttgatga catggtcatt ccttttaaag caagcatttt ctcgtaggtg
    19141 tctgttaagg gagtaaagcc actttcaaag gcattgctct gaataagctt gccgtcagta
    19201 tctacaaaat caaagtcagt attagaccat tttgaatctg gtgagctatc cagcaaatca
    19261 acctgctttt gtagcttgag agtatcagtc caatagtcat caccatcaca tctggcaata
    19321 tactgtccct ttgcctccaa acaagccttg acccaggttc ttgcaatccc aagatttacc
    19381 tcattaacga tgagtcgtat acgatctgga aagctggctt gatagtccat gaggatctgt
    19441 ctggaatagt ctgttgaagc gtcgtcaatg acaataattt caacatcaaa gctggtctgt
    19501 tgggctaaaa agctgtctaa ggcctctgaa atccaaggcc ccttattata attggtgcaa
    19561 ataatagaaa cttttttcat aggatgcttt ctaatgacaa ttattgatta atgagccagc
    19621 taccatttct ttgatataag ccactggcag agtccaaagc agacaggtca tctggagcaa
    19681 tatcgtttcg ttgaagcacg actaatgggg aatgattagc tgttaaaaag agcagcattt
    19741 gcccgttttg atcgcgaaca gtcacctcaa gctttaattt gatatcattt aggtgtgaga
    19801 gctgacactg gtaggatatg ttcttatgac caggaccact tgtcggttga tcctgtgaat
    19861 tgtcattata tacccaaata ttgcggtcaa tatcagtcaa cgaaaaggca acataggtag
    19921 gctcgtcctt taagacatga taggaaatct caaaggaaat gggctcatct ggactaaggc
    19981 ttggcttaga ggtcaacctc acctctaact ggcttgccaa atcagacaca ggctcagcag
    20041 cagctccttg ctcagcattt ttcaattcag tattatcaac actgtattgg ttagcgacat
    20101 caaagggttc gccgtaagcc ttgacaaggc cattttcgat gaggactgcg cgattgcagt
    20161 attttttgac agcccccata tcatgggtca ctagtatagt agtcttgccg ctctccttgc
    20221 gctccatgaa gtagtcattg cattttcgtt gaaaggcctc atcaccaaca gctaacacct
    20281 catcaagaat cagcacatct ccctgtgcct tgatagcgac agaaaaagca agacgaacct
    20341 gcatgcctga ggaataattt tttaattttt gattcatgaa atcatgcagc tcagcaaagt
    20401 caacgatatc atcatacata tcatcaacct cttctgtggt aaagcccagc attgcgccat
    20461 tcatgtagac attttcacgc ccagtcaact caggattaaa gccaacacca agctcgatga
    20521 aggacaccat tttcccctca actgtgacct gtcctttttc tggaacataa atttgagaaa
    20581 taatttttaa taaggttgat tttccagagc catttcgtcc aacgatgcca aaaaaatccc
    20641 ccttatacac gtcaaagcta atatccctta gcacatgctg ctcggtatag cccttaatgc
    20701 ctttaaaacg gttaacaaga gcagtacgaa agctcttggt tgcctctgtt ggcagcttaa
    20761 aggacttact gacatgatca actgttactg caatttcttt attagccatt agataatctc
    20821 cgcaaacttc ttagcatttt tattaaacac tgctacccca agtgctaata ggacaaatgg
    20881 aatgaggtaa ggaatgatga tatagcacca atttgtcgac atttgccaaa tggtcacatt
    20941 agctctgtca atcagcagat accgcaaatc ttgaataatc tgtgctaaag gattaagcat
    21001 caaaatcttg gcagcaagag ggtgtcggtc aaacacaaag gtaatcgggt agatgatggg
    21061 agtcacatac atacctgcct gcaatagaac ctcccaaacc tgagccaaat cacgataata
    21121 aacaaagacg gtagaaagca tcaaggccac accaactgta agaacagcca gctcaacaaa
    21181 gagtggtaag gccagataag cgtgaggaga taaagtaact ccattgatag ctgcaaaaac
    21241 caaaaccact aataggttga ttgaaaagtt aatcaatgct cctaaaactg ctgaaaaaac
    21301 gatagtatgc tttgaaaaat tcaattttct aagcaggtct cctcgcgata caatagagac
    21361 cattcccata ctggttgctt ctgagaaaaa ggaccaaatc acattggcaa gtaaaagagc
    21421 aaccggaaaa tgaggaacgt caccaccagt tcgcaaaaac ctgataaaca ccaaatacat
    21481 gatggtaaac atcatcaaag gctttaagat agaccacaaa taaccaatag cactgccctg
    21541 ataccttagt ttaaagtctg ttttaacaag ctctttcaaa agaatacgat tctttttact
    21601 caataattcc attattcttt tctcctatag ccaaatttgg tcatgatcaa tgccataaaa
    21661 acaagggtat gaaaggcacg atttttccga aagccatacg ctttgaaatc agacagacgc
    21721 tgatagaaag gcctatccaa aagccctacg taagcctcaa tcaatcttct gtcagccgga
    21781 tttagctgca agtctagcaa ttgccttgct tgatgttgac tagaaacaat aagccaccaa
    21841 tacttctcta tgagcttatg gggcttacgc cactgcttca gtcgcttaga ccaggttctt
    21901 gcccctaaaa cattagcatc atgctgacga tagagctctg ttgccacatc tagatacaca
    21961 agctctccct gcgctgctgc aatcaaggct aaataccaat catgcatcac cacatgctca
    22021 cagctcaccc actgctctgc cagcgcgtga ttaatcatca tagtgccgcc tgtgactgtg
    22081 ttttcagtca actcctggac tagctgagta ttagcatgat gtgattgtgt ttggatcata
    22141 ctctcatgac gtacttctaa gtcttgattg accaccttta ggtctgtgta gactagtaag
    22201 ggctcgctta tcttgtgctt ttgcgcttct gccagagtaa gctctaattt attgtctaac
    22261 cacacatcgt cttggtcact gaaaaaataa atatctgcct tttcatatgt taaaagggtg
    22321 tgaaagcttc gaatcacacc gaggttttcc tgcacatcag cattaatcaa gcaaattctc
    22381 ggatcctttt tagcaaaagc ctgaatgatg gcaagcgttt tatcagtaga gccatcatct
    22441 ctgactaata aggtccaatc ctgcaccgtc tgcctttgaa tgctttgtat ttgctctgct
    22501 aaaaaccgcg ccccgttgta ggtagacatt aaaatattaa tcttcatcta aaaataaggc
    22561 ctcatactct cctacaattt tctcccaggt atattctttg gcaatgattt gcttagctct
    22621 ttctcccaaa tcagcaaacg attccttttg atcaaccctg ttaatcagtc cagtaaggct
    22681 gcccttttct tttgtccaat aaagggctgc tgttttagca actgattgat taaaggtcac
    22741 tcccaaaacc aaattaagct gggtatgggc tagggcctcc aaaagacctg gattggtacc
    22801 tccaacctca tgcccatgaa tataagcaaa agcatgctca cgaatataag ctaaaagctg
    22861 cttatcatac tgtgttccaa caaattttac acgcgcgtcc ttatcacagc cagttgcact
    22921 aaccagccgc tcaaaataag gatttttgtc atggttgcaa ataataacca aatcccgctg
    22981 agtagatgat gccataaact ctctaatggc tgtttcatag ttgttttcag gaacaaagcg
    23041 ccccaaaatc aaatagtatt ggttttctgt tatctcaaat gtttgaaagt aagttctgac
    23101 tttttcatct gatgtagaca aacaagaccg ccctatttct gtcccatagg caataaaagt
    23161 cgtttttgcc caaggataag actttttgat gtaggcttca atgccaatat tatctgagat
    23221 gaccaaatca gcatgctttg tcatttgctt ttcggcgtat ttcaggtatt gctgaacagg
    23281 cttagaccat tttgaacgct tccattccag cccatcagga ttaatcaaca aacgcccacc
    23341 acgctggtga atctgctttg caaagggggc aataaagcct ccaatggtat tgcctagaac
    23401 ataaaaaata ggcttttgaa tatgatacct atcaatataa gctaaagcgt gactaatagc
    23461 catcatatca taagcaatca ctctagctgg accgagctta ggaggattga tataaaaaca
    23521 atctgctccc ttgtacacaa aatgctcctt gtgcttgcta tcgctcaagc aggcaatatg
    23581 ataggtaatg cttttgttgg tctgattagt gactaattct tcaacaaagg tctcaaaacc
    23641 accatacttt gctggtaaac cgcgacttcc gatgatgaaa acatcctgca tagcacactg
    23701 ccccattcta aaatataatt agtagtatta taccatataa acaggtctta tgcgacataa
    23761 aatccatgaa aagagagcca atctcctaga tcagctcttt agtgctatcg cttattcatt
    23821 gctgttgctt gtaaaaagcc tccagggctt cttgccaggt aggaatcaca aaaccagttg
    23881 ccttagcctt atcaagattc atggttgagt taaagggtct tttggcttta gcaggaaaag
    23941 ccgatgaatc cacaggcaca acctcgacag ctgtctcttt taagatttct ctagcaaaat
    24001 cataccaagt ggtgtcttct ttagcatcat ttgacaaatg ataatagcca taaggcttgc
    24061 gattgtctgc tagatgacac ataaactcag ccaaggtcct cgtccaggtt ggacgcccat
    24121 gctgatcatt gacgactgtc aagcgagagt gggtcttagc aaggttttgc atggtaaaca
    24181 caaaattctt gccataatga ccaaacaccc atgcggtacg aataatgtaa aattgcttgg
    24241 tatatcgctc aacagccagc tcacctaagc gcttagcacg accgtatgct gtttgaggat
    24301 caggagtatc tgtttctagc cattcctgac cagctggctt ttgaccatca aaaacgtaat
    24361 ccgttgaaat ataaaccaag gtcgccccgt agcgctcaca agccttggca atatgctcag
    24421 taccagctac attgatagct tcattcagtg cttttccttc ttcttcagca gcatcaactg
    24481 ctgtgtaggc tgcacagtga tacactaagc taggcttgac ctgagcaaaa acctcctcta
    24541 ctttagtcgc gttggtaata tccatttcag caacatcaac agcaacataa tcgacgcttc
    24601 gttcgtctaa aagataacga agctctgttc ctaattgacc attacttcct gtaattaaaa
    24661 tcatcttttc tcctttgtaa aggtcttatt tctttgagct aatcacgcag ctcactccca
    24721 tctaatccta agagaggctt ttttgatcag ctgaccctag caagaccttt gttgtggtat
    24781 cgtatcagcc ttgcttttta tctagctacc gaatacctag ggcaattctc gcatagcggc
    24841 tcatcttttc aacgctccaa acagggtacc agaccaactt tacctcaacc ttggtcacct
    24901 ctggaacatc tctcatcgca tcatgaatat gatcagtcaa caaatccgcc aaaggacagc
    24961 ccattgtggt caaggtcatg tcaatctcgg tatgaccatt gtcatcaaaa cgaatctcat
    25021 agaccaagcc tagattcaca atatcaatac ctagctccgg atcaataacc gttcccaaag
    25081 cttcaagaat ccgatccttg atagctgcaa cctgctcttc tgtgtatttt aatgtttcag
    25141 tcatagctat tcctttcact tttttcgaag acctgatatg atgccaagtc aaaaaccagc
    25201 ccaaagacca gcgcattcag catacctatg atgccctaag ctgactaaca ttgatagcct
    25261 ctttttagtc acccttacat taacactagt ctttagctac tggctagcaa aggtaatctc
    25321 ataaaccagt aactaggctt ggagtcgttg accataggcc actcaccgtc aaggagagat
    25381 aacgcatttc gggctcgtct cctattttta gctcgccgtt aaaaaggtcc accggacctt
    25441 tttaatcctc aatgaagtct ctgagctgct tgctgcggct tgggtggcgg agcttacgca
    25501 aagccttagc ctcaatttga cgaatccgtt cacgagtgac attgaagacc ttcccaacgt
    25561 cctctaatgt acgcattttc ccatcatcaa gcccaaagcg caggcgaaga acattttcct
    25621 cacgatctgt cagcgtatca agcacttcgt ctaattgctc acgaagaacc acacgagttg
    25681 tgtaatcaac aggattttca atcacttcat cttcaataaa atcacctaaa tgactgtcat
    25741 cctcttcacc gattggtgtt tcaagagaca ctggctcctg agcgattttc agaatttcac
    25801 gcaccttatc aggggtcatc tccatacgct ctgcgatctg ctctggagta ggatcctgcc
    25861 ccaattcttg aaggaggttg cgctgctcac gcactagttt attaatggtt tccaccatat
    25921 gcacaggaat ccgaatggta cgtgcctgat ctgcaatagc acgagtaatg gcctgacgaa
    25981 tccaccaggt cgcataggtc gaaaacttga agcccttaga ataatcaaac ttgtcaacag
    26041 ccttcattaa gcccatgtta ccttcttgaa tcaaatcaag aaattgcatg ccacgcccta
    26101 cataacgctt tgcaatcgac accaccaaac gcagattggc ctcagcaaga cgctgcttag
    26161 cctccatatc accagcggct actgcaaccg ctaaaacctt ttcctcatca cttgtcagca
    26221 gcggcaccac accgatctcc ttgagataca tgcgcacagg atcgttgacc ttggctgaat
    26281 tacttccgat aagctcctcg tctgtcagct cctctggctt aggctcttca acgacgtatt
    26341 tagatgaggg atttccttcc ttatctgtaa tggaaatgcc accatctgtc aaacgctcaa
    26401 gcaaatcatc aatttggtca gcatctaagg taaatggaat cacgagtttt tctgtgacct
    26461 catcatcagt agctgttcct tcctttttat gatgacgaat aaactccgca atttgaacgt
    26521 taaaggttgt aatttctttt tcttttgcca tattttcctc tattccattt ttcttttttc
    26581 agcaatgaaa cgctctaaag cctctagagc catctggtgg tcacccttac tgctagattc
    26641 cctaatctgc tttccttgcc tatgcagctc tctttgcttt agcaatgtca tttgccttga
    26701 taaaatatcc tcaatctcac cgctagctat ctcatcagga agattttcct ctaaaacccg
    26761 gtaataggct tggttaacct cttcagacag ttgcgatagg tcataggagg taatctgccc
    26821 tgtggccttt agctgctcat acagcgtctg aagggctggt gtatcaaaat aaaaatccgg
    26881 ccgatgacga aattcattga gcaaatagtc gtgatgaagc aggcgatgca ggaggtgact
    26941 ttctgtttta gccaaggctg tcatgctttt gttaatcggt aaggtcacca gagatgcctt
    27001 tggttgacta gcctgtcctt gttgtaagct ttgcctatct tgtagcctta aagcatttac
    27061 cgattgctcc acctgaaaat aatcaaaatc cggcagcaaa tcagccacct tattaatata
    27121 cgaattttgt gcggtgattg agggtgcttg agcaataatc tgtgatatat gctccacata
    27181 agcaatctgc gattgcaggt tatccatatt ttcaggcttc aggtgatcaa tcaaaaactc
    27241 aacactgcta atgcgcgagt gctggagcaa ttctgctaga gcctctggtg aatgctgctg
    27301 aacaaattca tcgggatcca ttctatttgg tattttcacg atctccactt gaaaatctgc
    27361 cagcagctca agagacttgg caatagcatt ttgcccggcg tcgtcaccat cataagtcaa
    27421 tacaaccttt tgtgtcagct gcttgaggtg cctaacatgc tctggcgtca aggctgtccc
    27481 catagaggca acagtattac catagcctgc ccggtaggct gcaataacgt ccataaagcc
    27541 ttccatcaaa aagacctcat gagtcttagc gattatcggc ttggccttat caaggtggta
    27601 aagctcatag gacttgttaa ataggaccgt agcccttgaa tttttatact tggcctgctg
    27661 cttttctata tcctctcttg cccagatacg tcctgaaaaa gcaatcatat tgcccttatc
    27721 atcacataag ggaaacatga ttcgatgacg aaaggcatca taaatagcat ttgattgttc
    27781 agaaacatga aacaagcctg aggctgttaa ttgcgcctca gtatactttt ttgacaaggc
    27841 ttgataaagg tagtccatct cgttaggcgc caagccaatc cgaaaatact ctattagctg
    27901 atcatcaagc cctctttgat aaagatactc cttggctctt tggccaatct ttgtcgtcat
    27961 caaaaccgca tggtaaaact tagcagcatc ttcatgaaga tcaattaaag cctgatgagg
    28021 gtgctgcttt tgactcaaac tagtctgact tggagcaaca gtaactgcca taccagcctt
    28081 atcagccaca atctgaacac tttctaaaaa aggaacctgc cgatattcct caataaactt
    28141 aaaaacatcc cccgacttac cgcagccaaa gcagtgaaag aactgtctat cttcgatgac
    28201 attaaaagag ggtgtttttt ctttatgaaa gggacacaat ccaaggtagt gccgaccagc
    28261 ccgcgataga tggacaactt ctccaataac atcaacaata ttgacattat gcttgatctg
    28321 agaaatcatc tctttgtcaa tagccaaacc gtcacctccc cacaaaaagc ccattgtaaa
    28381 tttacatttc attataccat tgaaaatgag ctttgtaaat tgtaaaagca caatccttca
    28441 tcatctaaag cccgctacat caagcaataa gctatgctaa agtattgacg tctcttatga
    28501 tcactagctt gactagcagt acagcattaa gtagctcatc agtccttgat aagctcttct
    28561 attagccttt ttgacctatt tgtgctatga taagattatc tgaaaaaagg ggagtcaatc
    28621 atgctcaaag aattaaaagc atttttattt agagggaata ttatcgacct agcagttgcg
    28681 gtgattgttg ggagcgcctt tagcgctatt gtcacatcat ttgtcaacga cattatcaca
    28741 ccgctgatcc taaacccagc cttgaaagct gcaaatgtgg aaaacattgc tcagctcgcc
    28801 tggaatggca tcaaatatgg cagctttctc agtgctatta tcaacttttt aattgttggt
    28861 accagccttt tctttgtggt taaggtcgct caaaaagcaa tgcctaaaaa gggagaggaa
    28921 gagcccgcta agcccaaaac accaactcag gaagaattat tacttgacat acgtgatttg
    28981 ttagccaaaa aataactcaa agctcttaca gcagctggac ctgtccggct gctttttgat
    29041 atacaagcac agagcactta gcgatcaaaa gataatagaa ccggctctat ttgctgtttt
    29101 agcatatcat tgctattttt atcagcagca agctaaggta aaaaaagaca aactagtatc
    29161 ctcatactgg tttgccttca aactaaggca gcctacaaag ggccgccttt tttatgatga
    29221 ttagaatttt ttacgtttgc gagctgcttc tgatttgcgt ttacgcttta cagaaggttt
    29281 ttcgtagaat tcacgcttgc gtgattcttg aagagtacca gctttagtaa cagaacgttt
    29341 gaaacgacga agagcatcat caagcgattc attcttacgt actactgttt ttgacatatg
    29401 tttcacctcc tcaagatatt gtaacatttt cacgttctag cttatcttac atgatttttc
    29461 ggaaaaagtc aatgatcttt tcttgatttt gaggtcattc ttaaaaaaat accttaaaat
    29521 ttgctgctgc attaggcatc acttggcaag gctattctac tgcatttcct gttaataatg
    29581 ctgcttcttg aataaaggcc ttgtatttgc catccttgtt taattgcttg atcaccttat
    29641 taatggtttg ccttaggtca tcactcccct ttggcatagc tacagcctta gcatctccat
    29701 cacttgcctg caatttaaat ggtgctaaag ccaggtcttt atgttgagct aaaaagcctg
    29761 cagctactgg tgcttccaaa tcaacagcct gcacctgccc agatttcaac tcattaatag
    29821 cctcacccat cacagttaga gaaacacagt tggctttatt aagctgctcc ttgactaggc
    29881 cctcctcgat gctgcctttt tgaacagcca cctttttgcc aactaagcta tccttattag
    29941 cataatgctt ggcatctgac gctttcacca aaatagcatt ttcagtttca tagtaagcct
    30001 cagaaaaatc atacactttg gcacgctctt tggtgtagga caaaccagaa atcgctatat
    30061 ccaccttacc agtttgcaga ctggataaga cattatcaaa attcatagca gagagttcaa
    30121 gcttaacccc tagttcatca gcaatggcct gtgccagctc aatgtctgct ccgacaatag
    30181 tatccttgcc gtcaaccaag gccttaaatt caaaaggagc atagtcaggg ctaacagcaa
    30241 ccaccagctt tcccttttcc tggatcctgt cttgaaggct cgtcttgtta gcttggccac
    30301 aagctgccaa agcaaaaaca gataccatag caagtgctcc aactaataat cgcttcatgt
    30361 tcatattata attattcctt ttcttgttga tgaatcttat tatattgcat tattattcaa
    30421 tggtcaagtt tttattgaat atttttcaag cactgcgata gtctgcttaa tcctgcctgt
    30481 agaacctgcg gctgacagca atagccgatt ctcacatgat ttgcttgatt aaagcgattt
    30541 cccggaacga ccaaggtacc gtaatcctcc agcagcctca aagcaaaggc ttccatgtcc
    30601 tcatctatat ctagcctaac aaaggccgtt gagacctcat tcggtctatg gtaggaggcc
    30661 ctggcttcac ctgttatcca gtcctctaag atagcaaggt tagtcctgat aatggcttga
    30721 ttgcgctgca atagcttgtc agcatgcttc aaggctagcg aagccaccat atcatcaaaa
    30781 acacctgcac agatcattgt gtaatctcga tataacctaa gctgatcaca gatggtctca
    30841 gaagcggcta cccagccaac tcgaatgccc ggaatcgaaa aggtttttga catgctatta
    30901 acagtaatcc ccttatcata caaatctgcc accgctaaaa gatgatcaga ggtaaaggaa
    30961 tgataaacct catcacttag caggtaaata tcatgctctc tagcaatatt gatgagctcc
    31021 tctaaataag gcttggtcat ataggcacct gttgggttgt tggcattgtt gatcatgatc
    31081 atttttgtgt tgggacgaat catggcacct agctcattaa ggtctggcag ccaagcctgc
    31141 tcctctctga tctgccaata atcaacctcc actccaagag aagctggaat atcatatagc
    31201 tgctgatagc taggatagtg agcaatcaca tgatcacctg cttcaagcag tgcataaata
    31261 accaaaaaat tggcacctgt tgccccattg gtttgcaaga tatttctagc tttctgctgc
    31321 tgataaagcc ctgccactgc ctgcttaaag tcaggagagc cttctatcca gccatagtct
    31381 aatggctttt gatgcagctg ctggtaaaag gcttgaggct gctcctgtgt taagtcaaag
    31441 agctcctcaa gcgttaatga agcaatagat gagccagcaa tatcgtatac agcacgtttt
    31501 tcatgctgat ttagccactc ttctacacca aataccggta gtttcataag atcaccttat
    31561 ttcttgcgta atatttatta caatatcgca taaaaataca attgtcaaat caaaaactat
    31621 cctttttttg ataagaatca tgtcctatct aacagttagt cctgattggt ctcgcatgaa
    31681 aggctactaa atagagcaaa aatcacataa aaagactccc aacccaccaa tcagcgggat
    31741 taggagcctg atagctcgta tcaattcatt gatttcagat cagagtgact atcatcactc
    31801 tactatgagc caatgactag gctaggcgga caacttctag ctgtgatcca cccattaata
    31861 ccaagtattt ttcgatcctt gcaatcccgt aggattggct cagagcctcg gcatataggt
    31921 ccatttgctg ctgatagcgc tgcttcagct cagctgactg ctgatagcga tctgtcttat
    31981 agtcaaaaag aacaatacga tcctcaaaaa gcaggtagcc atcaataata ccacgcacta
    32041 cgtactgctc ctgacttagg ctgtcttttt tcagcatcgc aaaaggagcc tcgcggtgta
    32101 ggcgctggtg atgctcttgc aggagctgcc ccaattcagt tgtcgcaaaa aaagaggtta
    32161 ccttttcaat gtcaagcctt gccttgacct ctgcgtcagc tgagacaagc tgtaaggtct
    32221 gttcaatatc accagcagta acctgatcag acattggaat acgctgcatg agctcatgca
    32281 ggcttgagcc gacctggcta ggctcaacag cctttttctt agaaaaatca ggaagctcaa
    32341 aggtcttggg cctatgataa ggctgatcta tgatatcaac accatcagta tccattagag
    32401 gctcataaag ggttttaagc tgactggggg ttctcaccgt cggcagctca atggccgcct
    32461 gatagcttgc attgagctct gacaccttat ccagcatgtc taaggcacgc gcaatgtcct
    32521 ctgtttgacg gttatccttg agatcatctg cttgcagcag ccctgagggc cttagctgac
    32581 caacagcttc tggtgttaag tcactgtcat caacaaatcg cacatcaata aacaagtcct
    32641 ccttgctaaa tgttgctgct atcgctagta gccagtcttg aaagctcagc aatctttctc
    32701 gactagctaa ggctaagcgt ccttcggagc tattgtcggc tgttttttcc tgtacctttt
    32761 ccttgctagc cttaccaatg aggtatacct ttttttctgc tcgcgtcatg gccacataca
    32821 agagacgcat ttgctctgat aaggtcgcca agcgtagctg ctgcttattg agctggtaag
    32881 gaagagtttc catcgtaacc ttgagcgacg ccaatttttc ttctcttaga agctccttta
    32941 cattggcgac atatttgata ccgattccct catctctatt tagaatgatt ggcgcctgta
    33001 ggtcagccat cgcaaagcgc ttgtcgcaat tcaaaatgaa cacgtaatga aattcaagtc
    33061 cctttgattt atgaattgtc atgaggttaa cagcatgctt aggcctttcg acctcaacat
    33121 ctgccaaatc attttgcgtc tccagcacct tatcaatcat gccaataaag cgtgagagtc
    33181 ccttgtagcc tgattgctca aattggtcag cccgtatagc aagggcgtaa aggtttgcct
    33241 gagcctgctc tgcctttggc tggcttgcta caaagtcaaa gtaaaagcga tcgttaaaaa
    33301 tcttccaaat cagctcataa agcgaatgaa gctttgcaaa ttgacgccag tctctcaagg
    33361 tcccatcaaa atcagccagc tttgtcatca gctcctgacc gatcagctct gggtgctcgc
    33421 cttgtcctct caagctattg ctaagcttgt catagaaggc ttgaggctgc ttttgtgagc
    33481 tgccttgcag tgagattctt gccagctgat cctcatcaaa ggaaaacatt ggcgagcgca
    33541 ttaaggccac tagggcataa tcattcaaag gattgttgat gcttcttagc gtatccagca
    33601 tgaccatcac ctcaactgat ttgaggtaat tttcttggcc accatcagca acgagaggaa
    33661 tgccatactg attaaagacc tgaaaaatag tgtcatttcg tgtgcgtgac gaaacaagca
    33721 gggtaatatc ttcaaaagca accttctcct cgttatagag cctgatgatt tccttagcca
    33781 ctaagatgac ctcacctgcg gagataccat cgttagctaa ggcttcctcg gtgccttctt
    33841 gaacttgatc ggtgtcatag agcagcaatt gggctcgatt gttaggatat ggctgtcttt
    33901 gtccctcact gcctgctacc agctggtgct tgtcatcata ggtaatctct cctaaagact
    33961 cgtccataag gcggctaaag acagcgttgg tgacatttag gacctctgac tgactgcgga
    34021 aattttcctt tagtaaaatc agcttgccat gctcgggatt gctttgataa tccttaaact
    34081 tttgattgaa gatttgagga tctgcttgcc taaagcgata gatggattgc ttgatatccc
    34141 caaccataaa acgattatgg ccattagaca gcagctctaa taggcgctcc tgcatgtgat
    34201 tgttatcttg gtattcatca accatgacct catgataatg accttggtaa gcttggcgaa
    34261 tatctggagc ctgttgtaaa atctcaatgg caaaatgagc tatatctgaa aattcaaagg
    34321 cattttcttg catttttgca gccaaataag cctctgaaaa gctgatcaca aaggcttgca
    34381 gcacctccaa aagtggtaag ctctcctgtt gataagcaag gatagtctcc aagtgcctaa
    34441 atcttaccag ctgctcctgt agcgatttga aaatagggta tttgtgaccg gctacagtta
    34501 tatcagctcc tgaaggaagt aaagctgtta gctcctgtgc tagctgacct agtcgcgctt
    34561 taccgtaaag gctgtcaaaa tgcaaagccc actcatataa gctgtcaatc attttgaggt
    34621 gcttagtgta tttggcagtt agcttgccag ccttggttgt ttgagcgtaa ccctccatgt
    34681 ctgtgaggtc tcgcagctga tcagcagtgt cctgcataca ggctaagaga gcatctacag
    34741 cttggtctgg aatatctgta aagctggtat aggtcttaga ccctcgtaaa aagacctctg
    34801 ccaaccaact gctaggattg gcagttgatt gactgaaggc ataaatgcta tcaacaatct
    34861 ctctaaaggc tgagctatcc ttacgacgtc cagaaaaatt ctgcaccagc tgtataaagg
    34921 ctttattgtc agtctgcgac atatagtctt caaaaacctg acgaaagacc tcgcgcttta
    34981 aaatgtcctg ctctgcctta tcctgtatga tacgaaaatg cggtgaaatc cctaaaacat
    35041 aaccatgctg gtgaaccaat ttctgagcaa aggcatccat cgtaccaata tcagcctgtg
    35101 ataaagcctg caattggtca ttaaggtagg ccttgagctg ataatcctga gtctctgcta
    35161 tagctgtgtg cagctttttt tcaattctct ctattagctc agtagctgct tttacggtaa
    35221 aggtcgaaat aaataagcaa tcaaccggaa tacctcttag aatcttatcc aaaatgcgct
    35281 caaccataac aaaggtctta cctgagccag cagatgctga tactaagata ttttgtccac
    35341 tgctataaat agcctcaatc tgctgcgctg tccgcttgtg cgtcttatct gataaggcct
    35401 cctcctgctg caaacgagca atagcctctg gcgttagaaa gccttcatca atcctcatgc
    35461 tttatctcct cattcattcg tgtcaagaaa gcctgtctcc tttcttttgt cggtaggacg
    35521 actaggcgtc tcgcgtaccc tagatctaaa tccgcctcaa agcgcgtgat ggccttgagc
    35581 tggtcaccct gaacagactt gccgtctgcg gtataagggt ttattaggaa atgccctgtt
    35641 ttaatctgct tcaccgcaga caaatatagc tgctcattat aagccagcag ggtttctagc
    35701 tcatcagtct cataaagtgt gttgttaagg tgatagctgc cattagccag atattccttg
    35761 gcttgggcta aaaaaatgcc cttataggtt aactccttgt aagccgcagc tactagctga
    35821 tcatcaagtg ccttaaagtc agacagactt agccttggct cttgcatgtg caggtacatg
    35881 gcgccaaaca ggccctgccc cttattcttt agggcagcaa gataggtcac aagctgagga
    35941 ctcaagccat tgtaaaaggc aacaatgtca aatacccttg cactggattt gtagtccaca
    36001 atgcccagcc taccatcagc tagctggtca atacggtcaa taacccctcg aataagcact
    36061 tgctgaccca gcgctagctc aaaggcctcc tcttgcttgg ttatctgcag gccttgatta
    36121 aggtctaaga cagaggctgt tgagtaagca atccccttta ggacctctaa gctatatcgc
    36181 ccttcagcat cagcctgata aacctgctga aaagcgcttt gctgattaac tgctgcaata
    36241 gctgcgccta gcttttggtc aaaggcagca ttagacctat ccttggttac caactcaaaa
    36301 atacggtgca ggtattgacc atgaatgcga gcatctgggt gaatagactc tggctcttgc
    36361 agccctagga catatttcaa gaaatacttg tattgattgt tataaaatac agtcaaggcc
    36421 gatgaagaca gattcaaggg ctgctgactt gaaaagcggg tctcaataac ctcaggtgct
    36481 actggcttag tagtcaaatg atgctcaaaa gctggaagac ttagctgctc atcggctagc
    36541 ctacgtttca aataacgaag ggcaaccgtc caaaagtttc tgtcctcact ggtcatgtca
    36601 tctgcaattc cctgccgatt aatagccacc aagcgagaca agagagcctt ataattgcca
    36661 atatctgccg ctgagtgtga caaacggttc tttccttttt caatgactgg aacaccaagg
    36721 gcaattagct ccttcaggta aggagagaca tcatctgagc tattcgttaa gcttgtaggc
    36781 aggcttaaca ccagctcctg cgtcgctgca ttaaacaggg aaagtgctgt ttggtgattt
    36841 ttcttgatat tttcaaagct cggcacatca aggcgctggt aagaggcagt ctgctcattg
    36901 atgcttgccc tttcctgatc agagatcagg ctggtgtttt ttgtctgctt aggaaaatgg
    36961 gagcgactca ggccaatcgc aaacacaaag ggcttggaat gcggctccac cagatcatag
    37021 gatttgatag acacaacatc taaggtcgca ggcactgtcc gataatgtgc tgtctgcatg
    37081 cccatcttga tcagagctag acagtctgca agggtcattt tttcctgacc aaacacctga
    37141 taaaaggtct ctaaaatgcc tgtgaaggct ttccaaacct cctcgtcctt ttccctatca
    37201 gtctcccttc tactgcctgc tagtgcctca aaattatcag ccagctgaat ggtcttaaaa
    37261 aaggtcatta gcttatcaag tagggaagcc cctagctgct tttgactctt aaagagctgc
    37321 tggagaggag tcaccacagc aagtcgcagc tgattcaaaa gaggcaaagg atactgacgt
    37381 gaggaattta gggtaaaggg tcttgaaaat ttggtgaagc cttgaatatc agcaaagacc
    37441 aagtattgct caagctgatc cagctctccc tcttgaaagc gcccaaagag tcctgatttt
    37501 agtaagttga caatatcctc acgtcgccaa ttgtatctgc ggcctctttc taaggattcg
    37561 acaaattgaa ccaaggggtg agcagacatc ggctcttgct tgccgatata ataagggatc
    37621 tcaaatttct caaaaatagg accaatttgc agctgataag acgccacatc acctaaaagg
    37681 acaagcatat ccttatagcg ataaccctga tagagcttct cacgaatagc ctttgcaaca
    37741 tgctcaagct cctctttttg attgagcgct tgccagatca caaccttgct cttgtccttg
    37801 gcactgagct gccaatcaag ctttgaatag tcatgattgg cttcaagaag ctgtgttagg
    37861 cgagaaaatg acacatcaaa gaccttttct gacgttgtgt agatcggctt ggtttgaaat
    37921 tgctgtgcca gctgttggat aaacgcaagg ctcgcctcgt agagatttcc cttggtaaag
    37981 gctagtcgat aagccttttg actgatatag gctccaataa cgatttcttc acaggcttcg
    38041 tttaagagcg ctagcagctg ctcctcctca gctgaaaagc gggtaaagcc atcaatcact
    38101 aatacggtct gccttagctc gtcatctagg ctcttgcttt tgatagcctc agcaagctga
    38161 gccagcctac ttgactggtc gtaatctcct tgtgcaatca gctgctcagc cttggtcata
    38221 atcgtgatca ggtcctcttg cttttctggt ctatcaagcg tcgttaagtc aaaggctgtc
    38281 agattagctg cttgcaattc cttatatagc tcaactaact gggcaataaa ggcctgatct
    38341 gtccgtagcc ggtgaaaaac ctttagctca tcttcttgca gctgcatgag cacacgataa
    38401 aaaatcatgg ctaagccatt atcatctaac gcttgtcgat tagctgcctt agctaaggta
    38461 aaataacgcg ccatctgctc aaagcgggtc accgtaatag caaaggaacc ctgctctggc
    38521 aataaggcta ggacagaacg ttccttttca aaggatagag agttaggagc aatataaaag
    38581 acacgatagc ccttatcagc ataagctctt gcctctttga ctaaaatctc tgtcatggaa
    38641 tagctaatct ctgtgtatag taatttcata aaactccttt tatttggacc tgatacaacg
    38701 tctatgcctc cattataaca aatcagcctt gcttttccca ttgttaatga tctttcaaac
    38761 gccacaagaa gcgctcacag catgaaaaaa gcctaccatt tcacatctgc tgctttgcgc
    38821 aagaaatgat aaggctttgt cttgtatagg ctcaaaaaac agactaagag ctcctagtta
    38881 agctgccctg tgcttgtctc ttgtgatctg tccccaggca ttctttttac gctgataacc
    38941 aataaagctg ctcaccttga taagggttaa taccgtatga agaacaaggc attggtagat
    39001 ggcagcatag attacccaag ccatatcaaa aagagtaatg ctactattgt tttgcaaata
    39061 aaccctattt aaaaacgatg tcaacgcaat aagcacacaa tagcaaatat agagcagcat
    39121 cagtgacaca aaaaaggttg tgtttaattg atggcatagc aaagacagca caatgataat
    39181 aacaccaaat gcctcaataa aaggagataa aagctcaaac aaaagataca gcacatagga
    39241 aatgagtacc gtcgctttaa accgacagct tacaaaaaac tggagatact ttttcaagca
    39301 ttgatacagt cctaaaaacc aacgacgcct ttgccgacac aaatccttca agcgactggg
    39361 cgcttggctc cagcaaatag cgtctgtttc atagccaata cgataaggaa tcttgttgtt
    39421 atggcagaaa aaatgtaatt tcatcaccag ctccatatct tctcccagag tcccagtgtc
    39481 ataaccatca acagcaatcg caagctcttt tttaaacagt ccaaacgctc ctgatatgat
    39541 taaattccca gcagcctggt ctaataaaac acgagctcca aaaaaggcac aatcatactc
    39601 aattgcctgc gcacacgaaa taagctgacg cggcaaatgg tagtctacga tcctcccagc
    39661 tgccaatgct actccctgcg aaaccttgac catgccccca acagcaatga cagacggatc
    39721 ctttgcagca gtctttgcaa tacgcttaag cgaatcctcc tgtagcatcg aatcagcgtc
    39781 catgcacaat aaataatcgt attgagcagc gttaatccca agattgaggc tatctccttt
    39841 gccgccattt gccttttcaa gcagggtcag cttgatatgc ttgagctgct tttggcttac
    39901 agcctttaga gggcgtgttg ggatccgctg attaatcgaa caagtcaccg cttctaaatg
    39961 aaactgctcc ttcaagagct tggcggtatg atctgttgac ccatcatcaa tgacaataat
    40021 ctcatagcag tcataatcaa gcatcagcaa ggactccact gtttcgataa tggttagctc
    40081 ttcattatag gccggaacca aaatagacac tggcggtaaa gaaacatcac caccaacagg
    40141 cgcttgctgt cgcctttcat aaaggtgaat agtcccaaca attaaggata gcagtaaaaa
    40201 gctcgcatag gcaatcaaaa acgctaaaaa aagatattgg gagtatttca atactaaaaa
    40261 cagtagctgc actatcattc tcctttaaca tgcaatcact tgtgcttacc attcgcctta
    40321 caaaagcgtc tcaaggtctg cttcatcaaa tacccgatat taaaggcaag gatcgctaag
    40381 caaacgatta tataaaaaaa caacaggtaa taaatcatct tatcttctcc tcttttcctg
    40441 ccagacagcc tgcacctgct gataggaggt ctttaaaact tctcttaccc ttggacgctc
    40501 ccagctcaac agtggatact ctaccattgc aatgaccttt gattccttta gcggtgcaaa
    40561 accaatagct attgcttcaa tggctaattc ctcaacacca tagtgctcaa aataatcatc
    40621 gtgtattttg tttgaagctg gatcagaaaa attgagcagc tgccagggaa tcctaagctc
    40681 aatcagacgc tcgccaaaag aaatatcggt ctgcgaatca aaatgagccg agcctcgttt
    40741 gccattgccc tgttttaatt ggccggtagg gtagcgcttc agtcctcttt ttgcaatcgg
    40801 aacctgatca atggctgcaa aaataccatc atttctcacc accatatcaa ccatagtaaa
    40861 tcttggcgta tgcttgttag ggggaaagac ataaaagtcc tttccattaa tctgcctaag
    40921 gtaattggca tcagtagcat ggtagcgctc ctgcaccaag aggcgactgc ctttgtggtc
    40981 atcaacaaca agggcaaaat cagcaaagcg atcaaaccga gcgctaaagc cttcaataac
    41041 cctgctgcct gttttgggcg taatgtctaa gggaatgagc cactgtcttt gtaagggctg
    41101 cttttttgtc gattcaatag caatatagag gtatttttcg tcctgatcaa cgaggagctg
    41161 ctgcccattt ttcttgtagg ttagagctct agaccactca tctgctgcct tttgcccatc
    41221 aatagcatgc gtccttggag catgctcaaa ggttaagaga ccataacctt gagccttaga
    41281 ctgaacatca ccccaaagaa agctttgatg tttattggtt gcaaaggagg tattccagct
    41341 cctagcagtc caatcgtcct gccagctatg gatcgttgca ccacagcagc cagacgcaat
    41401 aaaggctgtg taatctgcca tcaagcgctc gccttgatcc ttttctgtca aagggctgga
    41461 agtcgatatc atttggtcca cacctctggc tgtcgaatag ccatagcccg tcacaaccac
    41521 tgggacacga tgatagctcg tcagtagctt gacgtatccc tgatataagg gcatgcgctt
    41581 aatatcccca acaagcctat cagtaagccc tagacggtca aatagcagat aatccctata
    41641 agccgagtga caatccaaga gcttatagga agcaaaaaga ccggccttaa ccttagcgct
    41701 gggcttaata ttttcaatcg tcagttgaac atattttgct gcctgagagg caaagggatc
    41761 ctgatagaca aagggatctg attgaggcgt atttgaaaag ctcaccaagt gctgccagcc
    41821 atatttgcgg ctctcgtatg acgtgatttc ctccatgatt tcagccagta tagcctcaaa
    41881 ccgattggcc tgaggtgtcg ttgcataata ccttccctta aagcctacag gcttggcgtg
    41941 attctgatga ttggtatagg ctatcgtccc actgtaccaa tcatcaccaa caatatagcc
    42001 gagtagccat ttactcatat cctgatcata atgctgaagc cctaaatccg aatgccagat
    42061 ccgttttctc ccatgaatca catcaacact agccctagct tcccttaaca gagtgcctaa
    42121 ataagcctta tctaaggcgc tgatagaaga attgtcatga taagcatcta ttctaaagcc
    42181 ctgtaatagg tacagaggat gacttgctct gtcattgtag cgtctcaaag catggtaaaa
    42241 agtgacgggc ataataaccc ttaccctgat cgtatttgca cccatagctg ctatttgctt
    42301 gaaccaccta tagtaggttt tctcatcaac gctaaggtct cgtcgacgat agcctgctat
    42361 ggaactctcc acatcaacac ccttgatgag ataaggagat cccttttgat catatatgcg
    42421 cttgtccttg gtgtaaaaga ctgtccgaat agctgactgg ttagagaccg gcaggtacaa
    42481 gcgaccatca atatcacaac aataatagct caagccaatc acagacaaga gcaaaccaac
    42541 aaagattaaa tatttcttca tcactaccta ctccaataat gtattggtat ttttagacgg
    42601 tgcactgtac tgatagagcg tctcaatatg cttatccagc catcgcccac gacgtctaat
    42661 aaagtccttt agttgcttaa cagaggcctc atagctactg tagttacgac tggctggcac
    42721 aaggtaatta gtggcatcgc ttcttgatgg cactgtaaac acatagcccc acttatgata
    42781 attgcgctga atagccggac ctaaaaaagc aaccgtagca tcaatatact tgatcaaata
    42841 atccgttgat aaaacattct gtcggagctg atgatacctt gtgaccacca gcttaacaaa
    42901 gctaggatcc tttagcagca tgcaaaacca aggagcatct gatagggtaa agtccgcctc
    42961 atcataagga gcctcaatct gattatcaaa ggcgttgtta aaatcccaga ccaccagctt
    43021 gagcttatcg cgcaaatcct tataaagata ggttgaaaac ttcccagcat caatatttct
    43081 aaagaattca ttgataataa aatagtctgc aaaggactct tggtccagat aatcagtgta
    43141 ttgctttaaa tcataagaat ataggagctt ttcgatatga ctgatatcct tttcaataaa
    43201 ctgcttttgc ttaggcgtca gacggtgcag gcttgggtat ttaatgtcta aagaggacag
    43261 acctgcttga ttcgtatagg atacgtaatg atcaagagcc tgcttagcct tgtgtcttct
    43321 atcccaaaca aggatataag gcgttttatc agattttcta tcactttttt cgatgtttac
    43381 cctatgccgc ccctgctcaa tactctccac agccaaatac agaccacaat actgatgatc
    43441 caccactaac tcgcaatacc tgacgttagg tgcataggtc atgatctcac cggcaatatt
    43501 gtagctaaga taatttcgga ctagggtccg atctaaaaaa ggaccatgca gcacccactc
    43561 agactccttg gacatgccag ccagcgagac tgcctttggc ttagctcttt tattgataaa
    43621 ccttagcttt aaggatttct tgtcaaaatg acgtgacgaa ttgcccctat aagcaatcaa
    43681 tgctgtcaag gacaagcgcg gagactcaga caggctgtgc tctctatcta gctgatcacg
    43741 aagcgagacc gtcgttttaa tggttttttg ccgctttgtc tctccctcgt attccctttg
    43801 ctctggaatc tgctgatgat gagtgtcaat gctaataatc ggcaaatgag agctaaactc
    43861 cccagtgctt ctggagctct ttttgaccgt ctgcaaatgg tgatgaatac gctttgcaga
    43921 ggtcttagga aaaccgatac cacaaatagc agctagcaag agacacacca gcacaatcac
    43981 ataaatcgtc ttttctttca tttacgtcaa ccagttatgt catcgctttg actaacaata
    44041 ttaaaataat caactcgccc cagctgataa acagcctcag ttaacggatt agcctgctga
    44101 taggtgctgt cataatcctt tcttgacagc tcaaagatca tctcaatatc atcagacgtg
    44161 gtgtttttca cgctctggat cgccttaccc gaaaagtagt taaacactaa ccgctccagc
    44221 tcaatttcca tttgcttatc acagcgaaca atcaacaaca gtctattgtc atttctgaca
    44281 gctcccataa gcaacaaaag cataaagatc acgctgctac cagttgcagc gacagtataa
    44341 tcaccaacac cacagcaaat cccaaccaca atcgtccaaa aaatatagac tgtatctcta
    44401 gagtctttga ttgctgtccg aaaacgcaca accgacagcg caccgaccat accaagagac
    44461 aaagcaacat tatttccgat aactgtcatg acggttgctg ttaagaccgt caaggtcatc
    44521 aacgaaacat taaacttctt gctataggca gtcccagtgt gggtataggc atatgacata
    44581 taaatcacaa tacttaacaa ggctgcagca acaatatgca gcaaaacatc ttgaaagctc
    44641 aaggtcccac gctgttcaaa gacatgtctt aataattgtt tcatcttaat atctctccta
    44701 aaaacgataa tgcttgctga tagctctccc catgcaatac ttgcttgcac ttagctcgct
    44761 accattaaca gactccaaaa gctttttgat ataagacaac aaaaagccat tatacttgac
    44821 ctccaagatg accaaatagg gatctagcag gtaattctga ggcagatgat ctgaaaaaat
    44881 atcagcattg gtctcagacc cgataatatg atgatcaaag gtaatgcgaa tattgttttc
    44941 ctttgccaca aatgccttgc gctggtattc gatcactgtt tttggctgat agagctgcat
    45001 tgacatgcga ctatagcatt cagcagcaaa gcgatcagga taagtcagca atatagactt
    45061 gtctccctta atcaacaatt gagcgtctgc tctggtcaac ctcagagatc gctttttttg
    45121 attgctccct tgcttttgct tcatctccaa cttagcaaat gagctctgac taccgtaatt
    45181 gcgcaggcga atttttcgcc taagctcaat accgtcctct ttttcctgcc agtcaacgtc
    45241 ctccaaagaa tcaaaataca aggatcgaat cacatatccc tcactagagc tatgagcatc
    45301 tagacgcaag agcttggaaa attcatgcga taagcgataa taatcctcaa tggtaatcaa
    45361 atactttttt tcttgacgca atacctcatt cacgccagtg tcctcctttt tcgtctgtaa
    45421 gcaatgcctt aacaccaagc tgcctgtaac agcagccaac aaacctgtct cataaataag
    45481 tcagggcaaa taaggtgatt gttggctcta caagagtcaa tcacctgcca aaatagtaaa
    45541 tcctgccatc tgttgaaata atataaacca gctgatcgtc ttgattgcaa gacaggcgct
    45601 tttgtgactg atctagctgt ctgctgctaa tatcagttgc attagcctcc ttgagcatgg
    45661 cctgcttgag ctgttgctgg atttttctgg cttgcagctc agaaatctca aagctgccat
    45721 taaccttttg agccttgtgc ttgtagacca gtgccacatg gtctttagct gttgtcctag
    45781 cagtcgacag gagcccttct ttgttgagct gagtatgctc tcctacatca atggcaacat
    45841 agtcataggg tgcccgtatc cggtgcgctg ttagtattga ggacaaaatc cctgtcacaa
    45901 ggcagatgct tatcgtagcc actatcatct gctgccgctg cttacgaatg aaccttgaaa
    45961 aagcacagac ctccgcctga tattcctgaa gctcttcttc aaccttactg taatcctgtc
    46021 taagatcagc caagtcagtc tgacagtcct tgcagcttgt cagatgagcc tcaacaaccg
    46081 ctctactata atcactcaac gtatcatcta catataatgg caacaaatcc tggatcaact
    46141 cacaatcata cttcatagcc atactcctct cgtaattgtc ttttaatatg ttttcttgcc
    46201 ctaaagacaa gaaccttggc agaggatact gtgatgccaa tatccttagc tattttttca
    46261 taggaatctc ccgaataaat cctcgccaga aagacagcct gcattttctc tggaagatta
    46321 aaaataatcg ttagtgtaat ctctaacagc tcccttcttg ctatcttatc aagtggttca
    46381 tcatgccctt tagcatcaac gatttctaag ctttccatcg acatattctc atattttttc
    46441 tttttaattt ctgtaaagaa ggtgttcttt gcaatggtaa ataaccatgt tttgattgaa
    46501 ctatccccac taaatttagc aatattacga taagccttta gaaaagtctc ttgagtaata
    46561 tcatctgata aactattttg ataacagcac agcttattta caaacctata aacatcatct
    46621 ttatattcta aatatatgtc ctcaaattcc aacagcttgt ctcctctcaa tacaccctta
    46681 accattagac cgtccaatct gccaaaagtt acagattaat ttaattttta gtataagctg
    46741 tcatcaagtc agataaatag taatgatcta tcatcttatt attgactcaa acgacaaatt
    46801 atattgcatt ttagtataag ctgtcatcaa gtcaggtaaa taacaaggac atatcatcta
    46861 acatttgatc cagacaaaaa agacctgatt ctgtaatata cagaaccaag tctttctcaa
    46921 tagacattga ctagatgatt gatttatagc gacatagcta gataggctat gacttaccgt
    46981 cttttggatt tggagacaag cccgccaaga cctgccaaga taccactgcc agcaagagcc
    47041 aataaagcat ctagctgact agtgcctgtt ttagggagag tcttagctga gaactgagaa
    47101 acctctccag cagtctgagc agcaactaat ttctcctgat gatgggctgc ttgatcagtc
    47161 attgcaccta aagtcccctt atcagactgg gacgccctaa gacggataat ggtagctgtt
    47221 aagcctgata gcttgacccc gtccttggtt agcacaaccc cctcaggact tgccagcgcc
    47281 tcggtgcctg cttgcttggc atcgacgata acctcaccag caagaagagc ctgaaactca
    47341 ccagttagcc taatggtacg gtcattgcta tcagcattga caaagacagc ataaacatca
    47401 ccattgcttg ctgttgtctg ataagcaatc accaaatcct gtgccttgat cccatgctca
    47461 tttggaacag tgatcagctt gaccttctgg tctatctcag ccttacttgc caagcgaaag
    47521 gcatctgtcg aacggcgcag cgcaatcaat cccttagtaa aggcctgact tgtcgtgctt
    47581 tcagggtagc gctctgtatc cgttgccttt gcccagtcaa aatgattaat ggcatctgtc
    47641 gaatcatagg aatcatgaat aaagtatggg tattcaaatg gtgttccgtc ctcattgacc
    47701 aagaggtgtg atttatttgg caccttgtca tcagcgacct tgcccttata ggcttcgtcc
    47761 ttaaattgct ttgtacgacc atattcctga ccagcatgta ggaaaggggt gccttgagag
    47821 gttagcacca agaggttccc taggcgcaag cgacgatgaa tctctgccgc atttgctgca
    47881 acagacggat cctttttaat agactgggcg ataatatcaa acaaggtcag gttatcatgt
    47941 gcagcgatat actgaatcac atcacccgga tcatcagcca aaaagttagt cggctgagcc
    48001 ttgatattat gaaaaatggt catgatatcc ctagcaccgc ccgtaataaa ggctggagag
    48061 ccttcatttg gaaagcctga tttgagctga ttgcgaaaat catctgagaa ggaggcaacg
    48121 gtatctgtct gtgacatcca gctttggtcc gcaggctgct caggcatgtg ctcatcaccc
    48181 tgataggtga cccagccctc accaagcatg atgatattcg gattaagtgc cttagctgct
    48241 aaaaaggctt tttcaatagc tgctgcatca tggtccccca tcatgtcaaa acgaaaacca
    48301 tcaaccttat actcatccac cagataagta atcgaatcca ccaaaacacg acgactcatg
    48361 taatgcgttg tcccaagtcg tccaccacca aatgaggtcc tagcagtgcc atcagcattc
    48421 ataaagtgat aataattcgg ctccaggtcc tcaaaaatat caacattagc tgtatgattg
    48481 tagaccacat caaggataac ccccatacca cgcttatgga tttcattaac aagctgctta
    48541 aattcctcaa tgcgcttagc tgggtcggtt ggatcagtcg aatacatacc agtcaaggca
    48601 aaatagcttt gtggatcata gccccagttg taattattat cacttgagct gtaggtcagc
    48661 atacgctcct tgttggccaa ttcgttgaca aaataatagc tcatcacagg cagcagttga
    48721 acatgcgtaa taccaagctc cttgagataa tccaactttt caacaaaggc agcaaaagtc
    48781 ccaaattgag cctttagatc attagcaatc gcctgatctg aggtaaaatc acgaacatgt
    48841 gcctcataga taatggcgtc ctcacgctta tgaaagccct taatatcagc aaaggccagc
    48901 tccttatccc caatagcagc aggatcaaca atggccgcct tagccacctt ataggacggg
    48961 tctgtcttag caagctcgct gttccatgcc gctaacgatt tggcataagg gtccagcaca
    49021 aggacagact tgccatttct agtaatctca taatgataga aatagcctct ataatctgaa
    49081 atcccaagtc cgctatctgc tgatagagtg attgaccact ctcccttatc accctttgct
    49141 agagcgagat taccaatcac cttggtctga tcagccttat catacaaaac aagtgacacc
    49201 ttatcagcac ttggtgacca aatcgtcaga tcaaccttag cacctgcttc tctcacacgc
    49261 gctcctagct caccgtcata agcatacagg ctatccttgt attgccaatt tggcctagcc
    49321 tggaagctct catgatgaaa ggtcaccgta taagtggcca ctgcttgact aaaatcacct
    49381 gtgatgacag ccttatgagt cttttcatct aaggtgatat cagtaatagc aactgcttcc
    49441 ttactgtcag tgctgatttt taattctttt aaaaggcttt ccttatccac atctgctaga
    49501 gtcgtaaagc tcgcctcaat actgcttggg ctgacctgct gagcaccgat taatctaact
    49561 gtattaacaa aataagggtt cgtataaatg gttggatcct cgtctttcaa gaaaatttgg
    49621 gtgtgattct ttaaatcttt aaaaatataa tcattgggct gaattttaac agcgtcacct
    49681 gtctgacgct catctagcaa gagaaagcct agctcattgg tatcagctag cttgacatct
    49741 atataagcac catatcgacc gacctgctta aaatcaatac catctggcca agcgccctgc
    49801 tgactagtca ttgacgcatc agcacttccc caaagccaga gcgatttgtt gtcataatgg
    49861 ccatcactgc gataataatt gatacggata tagccctgag ccagcggccg atagtaagac
    49921 agctcctggc catcaatcca gacctcattc atcttagggc tgagaaggtc tatggttcga
    49981 tcgcccgtca gattgtctcc cttagtgtta ttgatcaaaa agctaacctt attggcttga
    50041 ttggctgaaa gcttaacgtc catgtaatag ccatagtcat ctgtcttcgc tagactaaaa
    50101 ttggtagccc cagtcggcca gcctcccagc tgatcagatg gtgtctcaac atcgtcccac
    50161 acccaaagac caagcgagga taggtcttga gctggcaggg tcttgaaatg cagccgcaag
    50221 gtctgctccg ctatcggctc ctctgagctt gtagcttctg gtgtctctag agagctgtct
    50281 gtcgtaacag acactatcga tgatgaaggc tgagactggt ctgtagtttc ctcatgcgcc
    50341 tgatcctcta caagaggtac agctactggc tgaacttcct tgacagtatc agcattgaca
    50401 gcagctgaca ccttagtcac atcagaaata ccagcaatat cactaatgtc agtagcttct
    50461 ggtagctcat ttgagccttg gtcagcagcc tctgacttga ccatgaccgc accatcagca
    50521 ggctcaacac tcgtcagact ctcagctgct gctgtgatct gcccactagc tgtccccaaa
    50581 gaaaaagcgg ttgcaatagc taccgaagcc actccaagct taagcttacg aatgccaaat
    50641 aattgacgct cttcaaacag cgcttgattt tcccttaacc ttttcatcat tcctccgtcc
    50701 ttatcctgat agttattaac accttaagta tacaaaagaa atcacaatag tgcaatcgtt
    50761 ttctttattg aaaacaatga tatttatgaa caaattagac aagaatcaac gcaagcgatt
    50821 tccttactga taaatacctg ctcccctcac taagaccagc ccactgcaaa gcagaaaagt
    50881 agcctaaaga gccttagtaa cagataaatg agcttaatgt tgcttcatca actagctggc
    50941 tgcaaccgtt ttgctctgat gtggtaacgt cttgtcatca tgactaagct tgacaaaaaa
    51001 cgctgttagt tacataatca acggtgcttg gtagccttcc attactcctt tgattgttat
    51061 accctaatga tacacaaaac ctcagttttt atagtagaat attacacttt gttttgacaa
    51121 agatgtttaa tcttgctaaa ataaacttat caatgaggga gtaccaatga tgacattcga
    51181 attcacatcg ttattcgatt tacaaactgc ttttccaaca gagcaggctt gcataaatca
    51241 tttagaaaat atcacttggg gtgacgtggt gatcagccct tttgacgcta cctcaaaggt
    51301 ctataaatgc aagggaaata aataccgttg caagaataca gggaagtatt tcactgtcaa
    51361 aacaggtact ctttttgata atactaagat taagctacaa aaatggttta tggcaatctg
    51421 gcttgtgact tctcacaaga gaggaatctc ctcagtgcaa ttatcaaaag agattgcagt
    51481 gacacaaaaa acagcatggt tcatgttaca gcgtattcgt aaatgctttg gctctgaaaa
    51541 ctgagatcca cttggtgacg tcgttgaagt agataaaact gatattgatg gtaaaaataa
    51601 gaaccaccat gatcctaaga aggcaaaaac gttcaagaac catccttctc tgaaagataa
    51661 gtcggcagtt attggaatgg tgcaacaaaa aagtaaggcc aacgctcata caatactcgt
    51721 gattactctg atagtcggcg ttttatcttt tatcagctaa tgctgatatg cgaacaactt
    51781 ataaggagct gatcaatggt taaacatgca aaaactaacc tacactttga attagaaaga
    51841 tctatctctc gcaaagttga tagtaaattg atagcctatc aagtcagtct ttcagatggc
    51901 ttttatgaca aatacaccaa attatgggat aaaacctatt catttgattt tgtcatcaac
    51961 catcgtgcgt tttatgctca gttgaccaaa agatgtgttt acgatgtcct tttgcaaact
    52021 ttggaaaaaa tcagtagaaa agccattgca aagcaactag cagagcttga agccttggtt
    52081 gatgtttcgg aaagtaagga agactttcag atatttttcg agaaaaaata caaactatca
    52141 tttcctgatt tgaagaattg tgtttatcca aagaaaaagg aactttccga ttttgatcaa
    52201 aacctctgga tagctctaca ttataaccct agaaaggaga gggatacata atgacaacat
    52261 ggtatgatta catggtaaga gccagcgaac actctggaag tgatggagac ctctggtttc
    52321 gttaccttta caaggttatc aaagacaaag aaaccaaact aactactgat gatgtggagc
    52381 agttattaaa aaatccgaat ctaactcctt ttcagaaggt aactctgcaa gatgctttaa
    52441 cagaaggtac gcatacaaga gagcatgttt tacaggcaaa ccgtaaaagt cagccaaagg
    52501 atattttgaa actctttaga gagggaaact atggataaaa aaatcttatt caaagctctg
    52561 aatacagaac tagctaaaga aaatattagc cttgacatta tctgtgtcgg tggttttgtc
    52621 cttgaatatt acaatctgcg aggaacacaa gatatcgatg ccttttatca agaaggtgtt
    52681 aacatcaggc agatgatcaa aaaggtggga gatgagtttg gcgttaatga acctgatgag
    52741 ctttggctta ataattcagt tgccaatctt aatagaatac cacctaaaac gatttgtgag
    52801 acagtatttc actattctaa cctaattgtc cttgtcccac ccttgtctta tattcttgga
    52861 atgaagctag aaagcggacg agatagggat agacaagatg ccggagacat tattaagcta
    52921 gctaatatcc gttcccctaa aaaacttatc aatacacttg aagagtatga ttttcaacct
    52981 gatatttcaa tgattttaga agtctttgaa atagcttatg gcatggaatg gttagcaaac
    53041 tatatgaccg aacacccaga agaatttagg cattattaaa agacgatttc tgtttggaag
    53101 tcgccttttt tgatgttttt gaaaacacct tgagattagt ctaaactaat ctccataagc
    53161 aaaaaacagc ttagccccgt ctgggagtaa gctgtttttg ctgtaatgta tgagataatt
    53221 aggctaacat caatcattac ataaagggaa taaagggtta atgtttcttg cgtttgcgtg
    53281 atactacagc tacgcctaga cttgccaata cggcaagggc tgctgctgta aagaatggag
    53341 ctgttgcttc tcctgttgac ggaagcttgt gttccattgc tttaggtacc gctggtttat
    53401 ctcctttctg tgcttc
//
LOCUS       DARYXZ010000007        53245 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYXZ010000007 DARYXZ010000000
VERSION     DARYXZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53245
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..317
                     /locus_tag="TV186_000334"
     CDS             <1..317
                     /locus_tag="TV186_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HEL1531766.1"
                     /translation="RGDVLLRKFKAESNKINGQIKTIKNELKVVDDKKRSIKRRKDEL
                     KKFIEALFYCLEDYKSIEVDKELVDTLINRIEISKYKQVTIYFKFSFDKDIEKQLEVE
                     HE"
     gene            310..1830
                     /locus_tag="TV186_000335"
     CDS             310..1830
                     /locus_tag="TV186_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1531767.1"
                     /translation="MNRIAIYLRLSEEDYKKTDESVSIVNQRDYVRNYIENENSLKDC
                     EIEEYIDDGFSATNTNRPSFLRLIDNIKAGRINTIIVKDMSRFSRDYILLGDYLSNIL
                     PFLKIRFIAINDNYDSINEDGNGIDTDIQFKTLYYDLFSKELSEKVKSSFKQLKSQGK
                     NTNWAAPFGYIKDPKDKHHIILDEKTAFIVKEAFDLLLEGYSCNQVANIFNEKDYITC
                     SERKEELKISEYTRNLVTGSKINKRVWTSATISRITSNELYTGDYVYNKYKETKMGGR
                     KRILLPEEEWEIIHNTHEAIVSREVFDKVRIIKKKRIFGGYAKNREESVFSDKIFCKE
                     CGRHMGFRCDSRQKKNPNKVYKYRNYYCYFCKASRTPNNVKERDIIELIRPKLDEFKL
                     QNTEKDKKTMDYEKIKEEYLREISALNSNLQIIYENYKKNSISKEEYLRKKILVQDRK
                     KLLENKIKELENVEDDSKKELDINNLDEDNLLKIYVDNIIDKIIASRTGEIEIIEK"
     gene            1871..2485
                     /locus_tag="TV186_000336"
                     /pseudo
     CDS             1871..2485
                     /locus_tag="TV186_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            3015..3893
                     /gene="mvk"
                     /locus_tag="TV186_000337"
     CDS             3015..3893
                     /gene="mvk"
                     /locus_tag="TV186_000337"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1531768.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            3875..4819
                     /gene="mvaD"
                     /locus_tag="TV186_000338"
     CDS             3875..4819
                     /gene="mvaD"
                     /locus_tag="TV186_000338"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1531769.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            4812..5810
                     /locus_tag="TV186_000339"
     CDS             4812..5810
                     /locus_tag="TV186_000339"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1531770.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            5813..6805
                     /locus_tag="TV186_000340"
     CDS             5813..6805
                     /locus_tag="TV186_000340"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1531771.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(7090..8373)
                     /locus_tag="TV186_000341"
     CDS             complement(7090..8373)
                     /locus_tag="TV186_000341"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1531772.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(8360..9535)
                     /locus_tag="TV186_000342"
     CDS             complement(8360..9535)
                     /locus_tag="TV186_000342"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1531773.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            9720..10559
                     /locus_tag="TV186_000343"
     CDS             9720..10559
                     /locus_tag="TV186_000343"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1531774.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            10640..11137
                     /locus_tag="TV186_000344"
     CDS             10640..11137
                     /locus_tag="TV186_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1531775.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            11157..11327
                     /locus_tag="TV186_000345"
     CDS             11157..11327
                     /locus_tag="TV186_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531776.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            11363..12592
                     /gene="clpX"
                     /locus_tag="TV186_000346"
     CDS             11363..12592
                     /gene="clpX"
                     /locus_tag="TV186_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1531777.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            12602..13201
                     /locus_tag="TV186_000347"
     CDS             12602..13201
                     /locus_tag="TV186_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1531778.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            13565..16567
                     /locus_tag="TV186_000348"
     CDS             13565..16567
                     /locus_tag="TV186_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1531779.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(16757..18850)
                     /locus_tag="TV186_000349"
     CDS             complement(16757..18850)
                     /locus_tag="TV186_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1531780.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            19221..19640
                     /gene="ndk"
                     /locus_tag="TV186_000350"
     CDS             19221..19640
                     /gene="ndk"
                     /locus_tag="TV186_000350"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1531781.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            20141..20947
                     /locus_tag="TV186_000351"
     CDS             20141..20947
                     /locus_tag="TV186_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1531782.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(21239..22204)
                     /locus_tag="TV186_000352"
     CDS             complement(21239..22204)
                     /locus_tag="TV186_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1531783.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            22376..23659
                     /locus_tag="TV186_000353"
     CDS             22376..23659
                     /locus_tag="TV186_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL1531784.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            23661..24521
                     /locus_tag="TV186_000354"
     CDS             23661..24521
                     /locus_tag="TV186_000354"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL1531785.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            24686..25945
                     /locus_tag="TV186_000355"
     CDS             24686..25945
                     /locus_tag="TV186_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL1531786.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            25945..26568
                     /gene="folE"
                     /locus_tag="TV186_000356"
     CDS             25945..26568
                     /gene="folE"
                     /locus_tag="TV186_000356"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL1531787.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            26576..27376
                     /gene="folP"
                     /locus_tag="TV186_000357"
     CDS             26576..27376
                     /gene="folP"
                     /locus_tag="TV186_000357"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL1531788.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            27383..27742
                     /gene="folB"
                     /locus_tag="TV186_000358"
     CDS             27383..27742
                     /gene="folB"
                     /locus_tag="TV186_000358"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL1531789.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            27739..28245
                     /gene="folK"
                     /locus_tag="TV186_000359"
     CDS             27739..28245
                     /gene="folK"
                     /locus_tag="TV186_000359"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL1531790.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            28341..29228
                     /gene="murB"
                     /locus_tag="TV186_000360"
     CDS             28341..29228
                     /gene="murB"
                     /locus_tag="TV186_000360"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL1531791.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            29274..30428
                     /locus_tag="TV186_000361"
     CDS             29274..30428
                     /locus_tag="TV186_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1531792.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            30412..31206
                     /locus_tag="TV186_000362"
     CDS             30412..31206
                     /locus_tag="TV186_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531793.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            31203..31979
                     /locus_tag="TV186_000363"
     CDS             31203..31979
                     /locus_tag="TV186_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531794.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            31972..33045
                     /locus_tag="TV186_000364"
     CDS             31972..33045
                     /locus_tag="TV186_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1531795.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            33203..34735
                     /locus_tag="TV186_000365"
     CDS             33203..34735
                     /locus_tag="TV186_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL1531796.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            34941..35555
                     /locus_tag="TV186_000366"
     CDS             34941..35555
                     /locus_tag="TV186_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL1531797.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            35903..37030
                     /locus_tag="TV186_000367"
     CDS             35903..37030
                     /locus_tag="TV186_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1531798.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            37182..37859
                     /gene="radC"
                     /locus_tag="TV186_000368"
     CDS             37182..37859
                     /gene="radC"
                     /locus_tag="TV186_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL1531799.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(37861..38556)
                     /locus_tag="TV186_000369"
     CDS             complement(37861..38556)
                     /locus_tag="TV186_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL1531800.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(38568..39212)
                     /locus_tag="TV186_000370"
     CDS             complement(38568..39212)
                     /locus_tag="TV186_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL1531801.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(39498..39845)
                     /locus_tag="TV186_000371"
     CDS             complement(39498..39845)
                     /locus_tag="TV186_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL1531802.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(39835..40962)
                     /locus_tag="TV186_000372"
     CDS             complement(39835..40962)
                     /locus_tag="TV186_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1531803.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(40965..41939)
                     /locus_tag="TV186_000373"
     CDS             complement(40965..41939)
                     /locus_tag="TV186_000373"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1531804.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(42074..42646)
                     /locus_tag="TV186_000374"
     CDS             complement(42074..42646)
                     /locus_tag="TV186_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL1531805.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            42741..43412
                     /locus_tag="TV186_000375"
     CDS             42741..43412
                     /locus_tag="TV186_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL1531806.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            43387..44223
                     /locus_tag="TV186_000376"
     CDS             43387..44223
                     /locus_tag="TV186_000376"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL1531807.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            44220..45122
                     /locus_tag="TV186_000377"
     CDS             44220..45122
                     /locus_tag="TV186_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1531808.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            45126..46127
                     /gene="pta"
                     /locus_tag="TV186_000378"
     CDS             45126..46127
                     /gene="pta"
                     /locus_tag="TV186_000378"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL1531809.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            46227..46985
                     /locus_tag="TV186_000379"
     CDS             46227..46985
                     /locus_tag="TV186_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1531810.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(47090..47776)
                     /locus_tag="TV186_000380"
     CDS             complement(47090..47776)
                     /locus_tag="TV186_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL1531811.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSDLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            48031..48759
                     /locus_tag="TV186_000381"
                     /pseudo
     CDS             48031..48759
                     /locus_tag="TV186_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            48752..50284
                     /locus_tag="TV186_000382"
                     /pseudo
     CDS             48752..50284
                     /locus_tag="TV186_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            50642..51625
                     /gene="guaC"
                     /locus_tag="TV186_000383"
     CDS             50642..51625
                     /gene="guaC"
                     /locus_tag="TV186_000383"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL1531812.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            51811..52392
                     /locus_tag="TV186_000384"
     CDS             51811..52392
                     /locus_tag="TV186_000384"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL1531813.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(52680..>53245)
                     /locus_tag="TV186_000385"
     CDS             complement(52680..>53245)
                     /locus_tag="TV186_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1531814.1"
                     /translation="DQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAALI
                     NLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQIK
                     DKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPEV
                     EGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        15314 a         9923 c        12137 g        15871 t
ORIGIN      
        1 ttagaggaga tgttctttta aggaaattta aagcagaaag taataaaata aatggacaga
       61 taaaaacgat aaaaaatgaa ttaaaggtag tagacgataa aaagaggagc ataaagagaa
      121 gaaaagatga actcaaaaaa ttcatagaag ccctatttta ctgcttagag gattacaaga
      181 gtatagaggt ggataaagaa ctggttgata ccttaattaa ccgtatagaa atctcaaaat
      241 acaagcaagt aactatatac tttaaattta gttttgataa agatatagaa aagcagttgg
      301 aggtagagca tgaatagaat agccatttat ttaagacttt cagaagaaga ttataaaaaa
      361 acggatgaaa gtgtaagtat agtaaatcag agagactatg taagaaatta cattgaaaat
      421 gagaactctc tgaaggattg tgagatagaa gaatatatag atgatggttt ttctgctaca
      481 aatacaaaca gaccttcgtt tttaagactt attgataata taaaagctgg gagaataaat
      541 acgataattg taaaggatat gtcgagattt tcaagagatt atatattgct tggagactat
      601 ctgagtaata tattgccctt tttgaaaata cggtttattg ctatcaatga taactatgat
      661 tcgataaacg aagatggaaa cgggatagat acagatatac agtttaagac cttgtattat
      721 gatttattca gtaaggaatt atcggaaaaa gtaaaaagtt cttttaaaca actcaaatca
      781 cagggcaaga atacaaattg ggcagcacct tttggatata taaaagatcc aaaagataaa
      841 catcatatta tacttgatga aaagacagct tttatagtga aagaagcttt tgacttgctg
      901 ttagagggat attcttgcaa tcaggtagca aatatattca atgaaaaaga ttatataacc
      961 tgttctgaaa gaaaagaaga actaaaaatt tcagagtata caagaaatct tgttactggt
     1021 agtaaaataa ataaaagagt ttggacaagt gcgactatat ccagaataac gagtaatgaa
     1081 ttatatacag gagattatgt atataataaa tacaaagaaa ccaaaatggg aggaagaaaa
     1141 agaatcttgc ttcctgaaga agaatgggaa ataattcata atactcatga agcgattgtt
     1201 tctagagaag tttttgataa ggtaaggata ataaagaaaa aaagaatttt cgggggatac
     1261 gcaaaaaaca gagaagaatc tgttttttct gacaagattt tttgtaaaga atgcggtaga
     1321 catatgggat ttagatgtga tagtaggcaa aagaaaaatc caaataaagt gtataaatat
     1381 agaaattact attgttattt ctgtaaagct agtagaactc ccaacaatgt caaagaaaga
     1441 gacattatag agttgataag accaaaatta gatgaattta agttacaaaa tacagaaaaa
     1501 gataaaaaaa cgatggatta tgaaaagata aaggaagagt atttaagaga aatatctgca
     1561 ttaaatagta acttgcaaat aatctatgag aattacaaga aaaatagtat ttcaaaagaa
     1621 gaatatttac gaaaaaaaat tcttgttcaa gacagaaaga agttactgga aaacaagata
     1681 aaagaattag aaaatgtaga agatgattcc aagaaagaac tggatattaa taacttagat
     1741 gaagataatt tgttgaaaat atatgtagat aatataattg ataaaataat tgcatcaaga
     1801 actggagaaa tagagattat agagaaatag ataattcagg aaattctata tcaattgctt
     1861 gacattgtag ggaaagtcct ctatcatgaa tttgctgtat cgcttttatg atgtacaatc
     1921 aggcctcatt acagttgatg ggcaaaatat tcaggagtat tctagagaaa gcctgcgttc
     1981 acagatgggt attgtcttgc aggatcctta tttgtttaca ggaacgattg cttctaatat
     2041 cacgatggga aatccagctt attcggatca ggatatttta gatgctttgg aaaaggtcgg
     2101 agcctcttcg atgattgctc gtctggaaaa gggcattcat gagcctgtct atgaaaaagg
     2161 ctcctcttat tcaagtggcg agcggcagct aattgctttt gctaggacat tgattgccga
     2221 ccctaaaatt ttgatcttag atgaagcgac ctcgcacatt gatactgaga cagaggacat
     2281 cattcaacag gctatggagg tcttaaagaa aggccgaaca acctttatca ttgcccatcg
     2341 cttgtctacc attcaatctg ctaatcaaat tttagtattg gataagggga ggatcgtcga
     2401 aagaggaaca catcaggaat tgctagatca gcaaggcatt tatgctgaaa tgtccaagct
     2461 acaagaaaag gtggctgtac agtaatgctt tttagtgata gctatcaaaa aattcctttt
     2521 ctaggccgtg ttaagcagca gtagtctgtg aagtaggagc tatatttagg ttttgtgcct
     2581 aagcctttaa ggtttttaag aggctggatt agggcttaac atcaataaaa tcatatgtca
     2641 ctttatcaca gcatgttgtg gtgaagtgtt ttttgtgtcg tcctgctaaa gggaagatcc
     2701 tcacagtcag ggcttggctg gctcctttat cagagtcaga tcattcatac gtacttcctg
     2761 tcaggcttgg ctaagttgaa ttgtatgttg agatcagcat gtcagcaatt tatgctttgt
     2821 gtctgacttt tagcagcttg tacatgaaat aggactaaag gacacttgaa ttgatgaaga
     2881 atcagcttaa aaaccatttg tcctagatag gataagaact gtctaaaagg gggatagatc
     2941 atcgcaattt ttaacaattt agtgtaaaat agtaaggtga atgttttgat gaaataaacg
     3001 aaaagattta ggatatgaat aagacaattg gatatggcaa ggcacacagc aaaatcattt
     3061 taatgggtga gcattctgtg gtctatggct accctgcgtt ggccttgccc ttaaaagata
     3121 ttgaagtgac ctgccggatt ttccctgctg caaagccctt agcctttgat ttttatgatc
     3181 ccttatcaac ggcagtttat gcagccttgg agcatttggg gtgcttggca gagcccattc
     3241 attatgatat tatgtctcag gtaccacaaa agcggggcat gggctcctca gcagctgttt
     3301 cgattgcagc tgttcgagct gttttttctt attttgggca gcccttgtca gatgagctgt
     3361 tggaaatctt ggtgaataag gcagaaatca ttgctcacac caatcccagt ggcctagatg
     3421 ctaagacctg cctcagtgat aaggccatca aatttattag aaatgttggt tttgatacca
     3481 ttgatattca gttaaatgct tatttggtca ttgctgatac agggattcag gggcatacgc
     3541 gtgaggctgt caataaggtg gctcaatttg aggaggaaaa tcttcctcat ttagccaagc
     3601 ttggctgttt cacagaggct gttgagcaag caattaagac aaacgattgc ctagctattg
     3661 gacgattcat gacgcaggca catgaatcac taaaggctat tggtgtcagt gtggcaaagg
     3721 ctgatcagct ggttgcagca gctcttgagg ctggcgcttt aggagctaaa atgactggtg
     3781 gtggcttagg aggatgtatg attgcattag ctgaaaggat aacagacgct cagcaaatca
     3841 gtaagaaact aaaagaagag ggagctgtaa atacgtggat tcaaatactg taacggtaac
     3901 ttcctacgct aatattgcta ttgtcaaata ctgggggaaa aaagatgagg ctaagatgat
     3961 cccatcaacc tctagtattt ctttgacctt ggaaggcatg tacacgacaa caagtctttc
     4021 ttttttgcct gcctcagcaa agggagatca gttttatatc aatggtgttc tgcaggacgc
     4081 caaggagcat gctaagatta ctgcgatttt ggatcagttc cgtcagaagg accagacttt
     4141 tgtcaaggtt gaagccagca acagcatgcc aactgcggca ggcttatcct caagctctag
     4201 tggcttatct gctctggtaa aggcctgcaa tcagcttttt caagctaagc taagtcaaga
     4261 agagcttgcc caaaaggcta agtttgcctc tggctctgct tcgcgttctt tttttggccc
     4321 tgttgctgcc tgggataagg atacaggctc tatttataag gtcaaaacag atttaaagct
     4381 ggccatgatt atgctggtct tgaacgatgc tagaaagccc atttcgagtc gagaggggat
     4441 gaagcgctgc agcacaacct caacaagctt tgaccagtgg ctggcccagt cagaaagtga
     4501 ttatcaggcc atgttgcgtg cccttagtga caatgatttt gaaacggttg gttggctgac
     4561 agaagcaaat gctctagcca tgcacgcaac gaccaaaaca gccagtcctt ccttctctta
     4621 cctaacagag gcctcctatc aggccatgct aagggtcaaa gagcttcgtc aagagggcta
     4681 ttcttgctat tttacgatgg acgctggtcc aaatgtcaag gtgctttgtt tagaagagga
     4741 cttagagcgg ctgtcgcacc tttttgaaag ggagtatcgt atcatcgcct caaaaacaaa
     4801 ggaattacca gatgtctaaa tatcatgttc aagcaggagg aaagctgtat ctgacaggcg
     4861 aatatgcgat tctaaggccg gggcaaacgg cgttgatttg ctatattccc ataatgctga
     4921 cagctgtcat tgaagcagca gaggctgtta gtatcagctc agatatgttt gaccatgctg
     4981 ctgatttgtc accggataag gattataggc tgattcaagc ctctattgaa gcctttagtt
     5041 tatatataga taaggatatt aaggagctgc cagccttttc tttgtctatt actggtaagc
     5101 ttgagcgtga cggtaaaaag tttgggattg gctctagcgg tagtgttgtt gtactaacgc
     5161 taagagcttt ggcagccttt tatcaggttc agctgctacc agagcagctc tttaagctgg
     5221 ctgcttatac cctgcttaaa tcaggagata atggctccat gggggacatt gcctgcattg
     5281 cctatgagag cttggttgct tatacatcct ttgataggcg taaggttggt caatggttga
     5341 tcgagatgac cctaaaagag ctaatggcag cacattgggg gtatacgatt gagactattg
     5401 agcctgctct gccctgttgg tttcttgttg gctggaccca agtcccttct atctcaagag
     5461 agatgattca gctggttaac aagagcatta gctgtcagtt tttagagcaa agccagctgg
     5521 tcacacagga agtgatgact gccctgcagc ttggtcaaag aaaaaggctc aaagctagca
     5581 ttgaaaaagc gggtcagttg ctgcaagggt tggcttcagt tatttatcac cctaagctta
     5641 cgcagcttgt ccaggcttgt caagggcttg atgctgctgc caaatcatca ggctcaggag
     5701 gtggggattg tggtattgca ctcgtttttg aggctaagga cattgagcct atccttgcca
     5761 gatggcagca agcagggatt gtattactat atcaggagga atggggataa acatgactaa
     5821 tcgtaaggat gaccatatca cacatgcttt gagctatcat tctccttaca atgcatttga
     5881 cgacatggag ctcattcact gttccttgcc gagctatgat ttagctgata ttgatctctc
     5941 aacccatttt gctggctgtg attttgagtt tcctttttat atcaatgcga tgacaggtgg
     6001 tagcaagaaa ggccaagcag tcaatgaaaa gctggccaaa gtggctgcgg ctacaggtat
     6061 tttaatggtg acaggctctt acagtgcagc cttgaaaaat cctgaggaca cttcctttca
     6121 attgcgaggt gtagcaccag atttacagtt ggccaccaac attggtcttg ataaggctgt
     6181 tgacctaggg attagagctg tcgaggaaat gaagcccttg tttttacagg tacatgtgaa
     6241 tgccatgcag gagctgttaa tgccagaggg agagcgcagc tttaagcatt ggaaggatca
     6301 tttagcggcc tatgccaagc agcttccagt ccctttgatt ttaaaagagg ttggctttgg
     6361 tatggatatt aagaccatca ctatagcacg tgatatggga gtaaaaacct ttgatatttc
     6421 aggaagagga ggaacctcct ttgcctacat cgaaaatcaa agaggaagta atcgctctta
     6481 cctagacgat tggggacaga caacagtgca atgtctatta aacgccaaag gtctggttga
     6541 tgaagtggag atcttagcct caggtggtgt cagacacccc ttagatatgg ttaaatgctt
     6601 ggtgctgggg gcacgtgctg tgggcctatc gcgagtggta ttggagttag ttgagaccta
     6661 tccagttgag cagatcatcg ctacgatcaa tagctggaag aaggagctta agctcatcat
     6721 gtgtgcttta gattgtcgaa ccttgagcga tttgcgtcag gtggattatt tattatatgg
     6781 taggctttat caggcaaacc gctaaagact ttttagccct gagctaactt tccttagaaa
     6841 atcatcacag gagttaagaa gctgcctgct tggtgctgca agctaattca gctgattatg
     6901 gctcgtaaga tttttagatg tctgaatgaa atgataggac agatgacata gtatagcgct
     6961 aatttctagt gaaaatcagt ccttggtcag gttactgaga ctgaggttaa gtttatgttt
     7021 acactaacac ttaaaggata tgaaaacact tggtagctgc cactgaagct gttaccaagt
     7081 gtttttagtc tatgattggc ttaatcgtat ggctgttaag agctgtcctg ccttttctag
     7141 gttcattggc ttatccttta gtagagcctt aactagttga ggcacctcct gctcactagc
     7201 acctgctaat agagctagag acttggcctg cagcttcatg tgaccagcct ggataccagt
     7261 tgaggtcaaa gcctttagag ccgcaaaatt ttgcgccagc ccaactgcag tggtgatttg
     7321 ggcgagaacc ttagcatttg gttgctctaa aaggctatga gcaacactga cggttgggtt
     7381 gagaccgatc gaccctcctt tactagcaat gggcattggc agtgttagct ctccgcataa
     7441 gctattttta gataaatcaa cgtgccagct acttagccct ctataagagc cagtccttgc
     7501 ggcataggca tgtgctccag cctcaatagc tctccagtca tttccggtag ctatagctac
     7561 cgcatcgatt ccattaaaga ttcccttatt atgcgttgct gctcggtaag ggtcaatctg
     7621 ggctaatttg cttgccagct ctattttttt ggccaattgc tgagcttctt ccttatgtcg
     7681 acttaggtat ctgaggtcaa cctgacattt agcactaact aaagcttttg ttgcatagtt
     7741 tgagaggata gccattaagc attgaccacc gcttagggcc tccaaatcag gtactaaagc
     7801 ctccatcatc gtgttaacga tgttggctcc catagcctct tgggtatcaa cgctcagata
     7861 gacaatgaaa aaatcctcct tacgctcaac ggtaaggctc tttgcgccac caccacgctt
     7921 aacaatagaa gggtaggcat tgtttgcaac gtcaatcaat gtatctgcgt tagctagaat
     7981 agccagccta gcctgctcgt catctttaac atcataaaga gctacctgcc caagcatttg
     8041 acgactgagt acctcagtct gaaagccacc tgatcgcttg atgattttgg cagcaaagga
     8101 agcagcagca acaacagaag gctcttcagt cacaaagggg acctgatagg tatgcccatt
     8161 gatcagaaaa tcaggggcta gactaaaagg cagagccagt cgaccgatga cattttcggt
     8221 catttgattg gcaatagcaa tgggtaagag ctggtctgtc tctaacagct tttgctgctg
     8281 cgggccaagc agctggtcat ctgcgagctg ttgaatgcgt tctgcaaggc tttttttata
     8341 aaagccggcc caatttggtt tagtttttgt catcatcttg ataaattcgt tggtgttcct
     8401 taatttcttt gagggcaaac ctgccagtta gatatggtga aaagctggca ttgccatctt
     8461 ggtctagtct aggctcttca taaaaaagtg cttcataatc agccactgaa atcacctgac
     8521 gttggtctaa tagggcttgt cgattagtca gtagcatgtc cttgtaaccg tcaacaagct
     8581 gccctgaaaa cagctcacta acagctcctg agccatagct aaacaatcca atcctatcac
     8641 cagcccttag cacctgacta ttctctaaaa gtgataataa gccgaggtag agtgagcctg
     8701 tgtaaatgtt gccgatttgc ttgctgtagg caatagaagc ttgaaagttt tcataaagcc
     8761 tttctttgtg atcatctgct agtgattttg tcatgatctt atgaagtccc tttagagcaa
     8821 gctttggaaa ggggatatga aaacaaacag cagcaaggtc tgatagctca ataccttctt
     8881 tttcttggta tttgtcccag gttgttttta gggaatcaag gtattgcttg gtcgaataaa
     8941 taccattgac aaatggtgtt gagctgtaat ttggacgcca aaaatccatc acatcacgtg
     9001 tctgtgcgac attgtcatga tttaactgga gaatacgagg attagtagta actagcatag
     9061 caatacttcc agcaccttgt gttggctctc cggcggatcc aatgccgtat ttggcgatgt
     9121 cactggcaat gaccaagacc ttggaggctg ggtgtgcagc aacatgtaat ttggcataat
     9181 ctaaagcagc agtagcgctg tagcaggctt cctttatctc aaaggagcgt gcaaagggct
     9241 gaatatcaag cagctgatga acgtaaatac tggctgcctt tgattgatca atgcttgatt
     9301 cggttgctaa aatgaccatg tcaatgcttg ctttatcgtc tttggtaagg atttggtcag
     9361 cagctgatgc agcaagcgtt acaatatcct ctgtaacagg tgcaatgctt agagcgtcaa
     9421 gcattagccc ctgatgaaat tttgctggat cagtgctgcg agcaagtgcc aggtcttcca
     9481 tttttaagac gtattgactg gtcgcaaagc caatcttatc aattccgatg ttcataaata
     9541 tccttctttt atccatttta tagtcctatc cattttatca tattttctta gaaaattagc
     9601 tgatttaata cgatagtttt acctttcaaa ccaaaaacag cagcatatag ctttcttctg
     9661 gtatttttga aggaaattag ataaaataat atggactgtg cttacagaaa ggggtttcca
     9721 tgacaaaagc agatcatatt tttaaagcta atatcaaaaa aattatggag gagggagtct
     9781 ttagcgagca ggctcgccca aggtacaaaa atggtcaaac agccaattcc aaatacatta
     9841 caggtgcttt tgcagagtat gatttgtcta agggagagtt tcctattaca actctaagat
     9901 caatccctat caagtcagct attaaagagt tattttggat ttatcaggac caatcaaaca
     9961 gccttgatgt tttagaaaac aaatacaacg ttcactattg gaatgagtgg gaggtcggtc
    10021 agacaagaac catcggtcag cgctacggtg caatcgttaa aaagcatgat atcatctcaa
    10081 aaatcctcaa gcagctagag gacaaccctt ggaatcgccg aaatgtgatt tctctgtggg
    10141 attacgaagc ctttgaagaa tcagaaggac tgctaccatg tgcctttcag gtgatgtttg
    10201 atgttaggcg agtagatggt gagctgtatt tagatgccac gctgacccag cgctcaaatg
    10261 atatgctagt ggctcatcat atcaatgcca tgcaatatgt tgccctgcag ctaatgattg
    10321 ccaagcattt tggctggaag gctggtaagt tcttttattt tgtcaataat ttgcacatct
    10381 atgacaacca atttgcgcaa gccaaggagc tattggagcg tcagccagca gcctgtcagc
    10441 ccaagctttt gctgcatgtt cctgatggga cagacttttt tgatataaga ccagaggatt
    10501 ttgagctaca ggattattac ccagtgaagc ctcagctcac ctttgacttg gcgatttaag
    10561 cgaaaaagac gattttttct gagcattttg ccaagaaatt tgatagaata aaagaagttc
    10621 atattgagga aagctagtga tgacaaagaa gattattgct atttgggcag aggatgaagc
    10681 aggacttatc ggagcgtgtg gcaggcttcc ttggtaccta ccaaaagagt tgcagcattt
    10741 caaggaaaca acattgaatc aagctatcct gatgggacga gtaacctttg agggcatgaa
    10801 gggtcgtttg ctgccaaatc gccaaacgct tgttatgacc agagacagtt attatcatgt
    10861 ggagggcgct ttaaccataa ccagtgtgca ggaggctttg gattggtatc atgcgcagga
    10921 taagacctta tatgtgattg gtggcagcaa ggttttagag gcctttgatg gttattttga
    10981 tgtcatcatc aaaacagtgg tacatcacca gtttgagggt gatacctacc gacctaggtt
    11041 agagctgagt gattttgtag aggagacctc tgtattgtac ccaagggacg ataacaatcc
    11101 ttacgatttc actgttacag tattgagaca tcgctaatat agggagatga tagtctatgc
    11161 agcgtagtat ttttggggta tttacggcct ttttgtgtgc gatttgtgtt ttatgtgcca
    11221 taccggcctt tagaaaaaat cgctatggct taggattact ttttttatta aatgccttta
    11281 ctaacctagt gaataccata catgcctttt atggaacact gttttaagcc taagagaatg
    11341 aaaagagaaa gatagaggaa tcatggcagg aaatcgtagt aacgatatta aggttcattg
    11401 ctcgttttgc ggcaagagcc aagacgaagt gaaaaaaatt attgcaggta ataacgtctt
    11461 tatttgtaac gaatgtgttg ccttatcaca agaaatcatc aaggaagaat tggcagaaga
    11521 ggttctcgct gatctgactg aggtaccaaa gccaaaagag ctgcttgaga ttttaaatca
    11581 atacgtcatt gggcaggagc gtgctaagag agccttatca gttgcagttt acaaccacta
    11641 caagaggatt tcatttactg agagtcgtga tgatgatgat gtggatttgc agaagtccaa
    11701 tattctgatg attggaccaa caggctcagg aaagaccttt ttggcacaga ccctggctaa
    11761 gagtctgaat gttccgtttg ctattgctga tgcaacctct ttgactgagg caggctatgt
    11821 cggagaagat gtggaaaata tcctcctgaa attaattcaa gccgctgatt acaatgttga
    11881 gcgtgcagag cgcggcatta tttatgttga cgaaattgat aaaatcgcta aaaaaggtga
    11941 gaatgtctct atcactcgtg acgtatcagg agaaggtgtc caacaagcct tgctaaaaat
    12001 cattgaagga acggttgcta gtgttccacc gcaaggtggt cgtaagcacc caaaccaaga
    12061 gatggtacag attgatacca aaaatatctt gtttatcgtc ggaggcgcct ttgatggtat
    12121 cgaagaaatt gtcaagcagc gcttgggaga aaagatcatt ggctttgggc aaaatagtcg
    12181 aaagattgat gacaatgctt cctatatgca ggagatcatt gctgaggata ttcaaaaatt
    12241 tggtctgatt cccgaattta ttggacgctt gcctgttgtg gcagcgcttg agcagcttaa
    12301 tactgaggat ttgattcgta ttttaacaga gcctagaaat gcccttgtga agcaatatca
    12361 agccttattg tcatatgatg gcgtagagct tgagtttgaa aagggggctc tggaggctat
    12421 tgcaggtagg gctattgagc gcaagactgg tgcgcgtggt ctgaggtcta ttattgaaga
    12481 aaccatgctg gatatcatgt ttgaggtgcc aagccaagag gaagtaatca aggtacgcat
    12541 tactaaggaa gctgtcgaag gtcaatcaaa gcctatttta gagatagcct aaggaggtat
    12601 gatgtctgaa gagcaaatcc ttaacacgca taatgcttcg atattgctta gtgcggcaaa
    12661 taagtctcat tacccacaag acgaccttcc tgagattgct ttggcaggtc ggtcaaatgt
    12721 tggaaaatca agctttatca atactatact aggacgtaaa agccttgcta gaacctcaag
    12781 caaacctggt aaaactcagc ttcttaattt ttttaacgtt gatgataagc taaggcttgt
    12841 tgacgttcct ggctatggtt atgctaaggt atctaaggca gagcgggcta gatggggaaa
    12901 gatgatcgaa gagtacctga ccacacgaca aaatctcaga gcagttgtta gtctggttga
    12961 ttttcgccat gagtcatcac aggacgacat tcagatgtat gagtttttga agtattatga
    13021 gattccggtg attattgtgg ctacaaaggc agacaaggtt cctcgtggtc gctggaataa
    13081 gcatgagtct atggttaaaa agtccttaaa ctttgatcaa acagatgcgt ttattatttt
    13141 ttcatctgtt gagcgtatcg gtattgatga gtcttgggat accattttag agtatttata
    13201 agcatatggt aaaaaattta agtatctttt agacaggcac ttgtgtctgg tctgagaggt
    13261 gcttttttat tgacaaaaaa acaatttgtt gatgacgagc ttgtgttcaa aaatgtcagt
    13321 ttgctaaaaa atgatgataa caaacaagac ttttatgata taatgcttag caggataata
    13381 tggagacatg agaaaaaggt cagagacagc taatttgcta tccctgatta taactatgat
    13441 gaccagcatt attataatac tcatggtgct agctattagt agcagcacct aacctatagt
    13501 gttgcttttt aggttacaag cactggcgct aggagtatta taatatattt agaaaggttt
    13561 ttttatgaca ataaaaaaat gccctcaaat acttgcctta ttccttgctt ttgcagcgct
    13621 agctagtcag gggcaaaccg tccatgctct ggagcggcag gagacatctg tcaagcaagc
    13681 tcatgaatca gatgattggt ttgatgagga cgaaggagtt agcgatatca agtctaatac
    13741 ccctacagag atagactcaa cagtaacaga gttatttggt gatgctgagc ctaagactaa
    13801 ggctgaaaaa gaagagtcaa aagctccaag ccctaagcaa gaagcactgc cagcagagtc
    13861 tcaaaaagaa aaagagacat ctgctaaatc gactgaccat gcgacagtac aagcagaaga
    13921 ggcacagcct gagcaaggct cagatagtcc ttggctagca gatgactttg ttactaaggg
    13981 agataccttg gttgggctat ctaaggcagg tcttgctaag ttatcaaaga cacctgtctt
    14041 ggtactacca aggataggga ttgacaagac agtgttgaca aggattgcta gctttgcctt
    14101 tactccaaat aaatcagtcg ctattgctga ttatacaggt agagcaggtg aacatggcga
    14161 gatcaatcat ctggacgtcg aaggcagaga tatccttact gagggagagg attttggtgc
    14221 ctatgcgatt aaaaagcttg tgattcctga aggctatctt tttatcggtc aagatgcctt
    14281 taatgacaat aaacagctag aagaaatcag tctacctgat agcttactca gtatttcaga
    14341 ctatgccttt gctcacatga gtttatctaa gcttaagctg ccaaaaagcc tacagtccat
    14401 tggagatcaa gccttttttg ataatcggat tgcaggcact ttggtattgc caaaagctct
    14461 aaagcagctg ggagaacgcg tctttaagtc caatcgcctc actggacttg tctttgaggg
    14521 agaaggcttg tctgtcctaa aagaagcagc ctttcaagac aatgctttca ttagtcttgt
    14581 tatcccagat agcattcaag ccttagaaga ggacgtcttt acaggaaacc ttggcgatga
    14641 agaatacggt aatcatgccg ttttacgaac caaaaatggt cagaatcctt acagacttca
    14701 cagtgccaat gttcttgtca atccaagtga tcaggctaga acaccacagc caccaattga
    14761 ttacaacagg tggcttgcag aagattttac ctatactgga cagacgataa ccggtttttc
    14821 agctagtgga ctgcgcaagg tcaaacgcaa taagcatttg gttctgccta agaattatca
    14881 gggtcagccc ttgacagcca ttgcagataa tgcctttaga aatgtcaatt ttcatgataa
    14941 aaccttgcgt aaatacgacc tagaaagcgt gacgttacca tctaccattc aaaagattgg
    15001 tgcctttgcc tttcagtcaa ataatctaga aagctttgag gccagcgagg acttggttga
    15061 gattggtcaa ggagccttta tgaataatcg cattgagatt ctggccttga atgataagct
    15121 gaaggtcatt ggagatgcgg cctttcatat caatcggatt tatgctattg ttatccctga
    15181 gtcggtcgaa gtaattggca tttctgcctt taggcaaaat ggtgctaaac atgtgatgtt
    15241 tatgggagat aagctaataa gtattggaga aatggctttt ttgagcaata ctctggagga
    15301 agtggatttg agcagcttag cagggcttaa gaccatcgct gttcaagcct ttgcagacaa
    15361 tcacttgaga gagcttaagc tgccagatag tttgatgcgt attgaagcag aagcttttaa
    15421 aattaataga cttcaaagag tgaccgttcc agacactgtc attagcatta gctttaatgc
    15481 ctttgatcat aatagtgatg acaaggttgt cctaaggacc accaatcaca ataaaaacct
    15541 gctagctgat ggaaatggct ttattgtgga tccagaccta ttaagtgcgg atcaatcgac
    15601 tgttcaagca gttttagagg acctgcggcg cttagatcta gctagtctac gtgctgatac
    15661 agcagctcat tttatgacac tcatcacaag aggtaagcag ctactaaaag aatccgctgt
    15721 acggttaggt tatcagctta ggttccttgc agagtcacga tttttcttag ggcgcgtgag
    15781 actggatcag ctgattaaaa ctgctgacat aaccctatct agccatcaag acacacctaa
    15841 tgctaagctg ttgatggcta agctagacaa ggccaagctg cattacaata atagcgcaat
    15901 gactgctcca aaagtaagtc gcttggaaaa agagctcagc ctgttaattg atcttgtcca
    15961 aggggtaggc gctatctcta aagcaacaat gactcaaggt gtctataagc ttcagacaac
    16021 cctacctatt ccagagtatt atattggggt taatctttat actgatgatc aggggaatat
    16081 tttatttgtg cttgacatga gtgatacgat tgggcaggga caacttgatg actatggcaa
    16141 tcctatttta aatgttgatg aggataatga aggctaccat gctttggcca ttgagtcctt
    16201 agcagattac gaaggcctta cgattaagga tatattgacc aaggagctaa atcaattgcc
    16261 tattcgcgat gtcaagcaag caagagagca tcgtgttggt ctttttatgg caatcagaga
    16321 tgctgcaagg gaagctcagc ttctactaga aaagcagagc aaagccttat cagaatcagc
    16381 cggcaaatct aatggctcaa aagtagctga ctcaggactt gagccttctg tgacactatc
    16441 aaccaataag actaagctgc taccaaaaac aggagccttc aaagaagctt gggtgacaat
    16501 gatcggaatg cttgttcttt tggcggctac cctacttaaa ggcgatagtc gctacaaaaa
    16561 gaagtaaata ggcttgctta gcaagcacac tctagcacca gtaaggcttg aggggcttac
    16621 aaagcctatc taatctagca atagtatatt gccagtgtga gctggtgctt gagcttcaaa
    16681 aaaacaaaag agcctgaaat gacttttact agcatttcag gctcttttta gcttgtgatt
    16741 cttttttgtg tgaagcttac ttctcactta tcgtaatagt atcttgatca aggcttgcta
    16801 ataggtgttt agcagtcggg tgatccaggt agtaatccgt aatgcggtca cgaatttctt
    16861 gttcgatgac acgtctaagt ggacgaactc ccatcgcatg atcatagccc agatcaatca
    16921 aacgctcttt aacatcgtca gtcacctcaa ggctaatgcc ttttttagca agggtttggt
    16981 tcacttctgt tagcattaaa gcaacaattt cttgtaaatc ctttttcgct aaatggttga
    17041 attcgatgac accgttgaag cgattcaaga attctggtct aaagtaaggt gcaatacgct
    17101 ccatgatagc aggctcttga tcagcacgat ctcctgcttg atggccaaaa ccagcattag
    17161 aggttgcgat gataaccgta tttttgaaat tgatcgtgtt gccttgtcca tctgtcaatc
    17221 gcccatcatc aagcacttga agaagcagtg taatgacctg tgggtctgct ttttcgattt
    17281 catcaagcaa gatgatagag taaggactgc gacggacacg ttctgtaagg gtattttgat
    17341 tatcatcata gccaacatag ccagctgttg ttccgattaa tttggaaaca gctgtgcggt
    17401 cactatattc agacatatct aagcgaatga tagcgtcctt tgagccgaac atatcaaggg
    17461 ctaactgctt agccagctcg gtcttaccaa caccagttgg accaacaaag aggaaggagc
    17521 caattgggcg attaccgtca tcaaagcctg cgcggttgcg tcgaatcgca cgagcaacag
    17581 cctcaactgc accatcttgt ccgataacat ggcctttaag acggttactg atttccttga
    17641 gcctttctaa atcactagcc cccatatttg atactggaac accagttaga cgttcaacag
    17701 attctgcaat atcattaaca gtggcagtga ccttttgccc ttcactgtga tgattgattt
    17761 gcttttggag ctcctcaatg cgggtcttag cagttaaggc cttttcaaag tcttcttctg
    17821 caacagcctt ttcctgtagc tccttttgct tagtgatttc tgcttcaagt gattttagat
    17881 cagtgacagg gtgctgagct gctagatgag cagcagtcat atcaacaagg tcaatggctt
    17941 tatctggtag gcttcgttgt ggaatatatt ggatagcata atcaatagct gccttcaaga
    18001 cagagtctgg taggatcaca ttgtggtgct gctcgtagag gttgcgaatg cccattaaaa
    18061 tgtggaaggt atcctctgct gaaggagcat taaccttaac ctcgttgaaa cgacgagcaa
    18121 gagcagcatt ttttagaatg gtgttgcgat actcatcttg agttgtggca ccaatcaggg
    18181 tcaactcacc gcgtgagagg gctggtttta gaatatcagc taagccctta gagcctgagt
    18241 ctgaaccagc tgaccctgca ccaaggattt gatggatttc gtcaaagaag agaatgatat
    18301 tgccagcctc cttaacctct ttaaccatgt tttgaatgtt ttcttcaaag gagccacgat
    18361 actgtgtgcc agcctcaagg ccagaaatat caattgagat aatctcttta tttttgatgg
    18421 cagctggcac atcaccgttg acaatagcct gggctaggcc ttcgacaaca gcagttttac
    18481 caacaccagc gtcaccgaca agaacagggt tattcttggt tcgtcttgct agaatttctg
    18541 cggtcgcttg aatctcatcg tttcgtccga tcacaggatc taacctgcct tgccgagctt
    18601 cttcggtcag gtttgttccg agcttggtta gaatgccgtc ttttttaagg ctgctagcct
    18661 gtttttcttg tccctcagct gcagctagct taccggtttt ccggtattct tgaaattcct
    18721 ctggtgtcat ctcacgtcca ttgacaagat agcgacgatt ttcgctgcgg tagccgccga
    18781 tgtttcccat taactgattg aaaatatcgt ccatattttc aaaggggtct tttccataat
    18841 aggttgccat atacacttac ctcacttgta ttatatttac cagtcattat gagctactgg
    18901 tataggtaga aggtgatcgg tgttggctca tacagagatc atagagaggt cttatgagag
    18961 tctattgctc aggcttatta ctcaccttct aataatatta tatccaaaag gtcagtaaag
    19021 gtcaaacaaa aagtatgaat aattaacctt tataatcagg tgcttatagc ccttgaaaca
    19081 tcagatgact atgccataag ctgctggtgc ttttttgcta gcaaggctat ctgtaaagaa
    19141 gagacttttg tcaaaaatgg ttttactttt tgttctaaag gctttcatga tataataaaa
    19201 gaaaagcaca gaggtcaatt atggaacaaa cattttttat ggtgaagcct gatggtgtga
    19261 aacgtggctt ggttggagag attctacgcc ggattgagcg tcgtggcttt acctttgata
    19321 ggcttgaatt gcgacaagca accccagaat tgctagctaa gcattatgac accttaatca
    19381 ataagccctt ttatccagag ctagaggcct atatgacaag cggacctgtt ttaatcggca
    19441 ttatctccgg taatcgtgtg gtctcttcct ggcgaaccat gatgggggta accaatccta
    19501 aagacgcttt accggggact attcgtggtg attttgctca agcccctggt gatgatggcg
    19561 gcattttcaa cgtggtgcat ggttcggatt cgagagattc agccaagcga gaaattgcga
    19621 tctggtttgg acatagctga cattgggctt gggcctattc ttttaagaac tgataaagca
    19681 attgcataag gggttgataa gcccatcatc aatagtagct cagcattaga agggtaacag
    19741 ccttgatgtt gggctatttt tttgcttgcc tagggtctgt atgcttgtcc tgatgagcag
    19801 gtagacaaag cagcataagt ttaacaatcc tttgcggcag tgatcaattg tagctctaac
    19861 catagcatca gctatttgaa agccttgaaa aagaaagcta aggctaacaa gctagtctag
    19921 gtcatttact acaagcgact tttttcaatt agctgctcaa ggcaagtatt gaaaaaagtc
    19981 catttttcat gtcatttgta ataatatggt atatttttaa cgaaaagtcg ttttagttga
    20041 gaaaatatac aaaaaaggct atgatatagt taataaagtt gttatacccc ctgtgtcttg
    20101 tacactatga cttgtagaga gtttatcaaa ggaggataag atgaacaaac aaagcatgac
    20161 ccatttttct aagaagctga tgaagttagc ccttttaggt ttggcattgc cattaagctt
    20221 ggtgtcggtg gtagatactc cggttcttaa ccaatccgaa aaagctgttt atgccaatga
    20281 ttttggatct ggaaatcgag ccagtgatta tgtaccggcg gctaacgctt ggagctttga
    20341 ggcttatcca gattactaca gtattttagg agctagtcat cttaatcctg ctgtctttcc
    20401 agagcctagt aagatgtcat acagtccttt agacgagttg ggccgcacac aggtcgcaag
    20461 aggaacaata acctatcaca atatcgtgat gaattacaat gttcggcaac gctttgctaa
    20521 aaatcagaac ccttcaggct ggattggtaa ccctagaaat gttcgctaca ctattgagtg
    20581 gctagatgga ctatcctatc agggagattt ttggaatcgg agtcatttga ttgcagatag
    20641 ccttggtgga gcagccttac gtgtcaatgc tattactggt acaagaacac aaaatgttgg
    20701 cggcagaaat caaagaggcg gtatgcgcta tattgagcaa aaggtgcagc agtggattga
    20761 gcagcataca agcgcagttg tttattacga agcggtgcca atttaccagg caaatgagct
    20821 agttccaaga gctgttgttg tttcagcatt gtcatcagac ggaggtcttg acgaaaaggt
    20881 catggtctat aataccgcca acggctatac cattgattat gccactggcg cattccgcag
    20941 taactaggct tttgtactaa gctgtagctg atcaaggtct gactaagaca agctcatcag
    21001 caattggtat ataaaaagac gtggcaacaa catgttttaa atgagttgtc atgtcttttt
    21061 agtgtcgtca gcttttcaca ttgtcttaga atgatcacac ctagctagcc gctaaaagca
    21121 ttggtccaaa gaaatgttaa gaatagatag aatgcctttt aatcagtggt atgggactgc
    21181 tagctaatat aatgcctgca gttgagccaa tttctcatct aggctaataa ctaacaagct
    21241 attgacttat cgtgttcatt agaatgtcag ctgttgtagt tggtagtatt cgaatacgat
    21301 taagcgatag caggccatta gcagcacttg ctagtccttc atttgttgtg acccctaatt
    21361 tgtaatgcag atcctcagca atctttaatg tggtatcagt ataacgacct gctggatagg
    21421 caattgcaat ggtatcttgg tgtagctctc tatctaggta ttctttagaa tctttcattt
    21481 cagcggtttg actagcagcg cttgcctgag atagatcagg gtggttaacc gtatgatctt
    21541 ggaaagacat gcctgcctgc ttcatttcct tcatctgatc caatgtaaga ttggccgcat
    21601 tacctgcctc tgtaaagcca gtgataacgt tattggtggc cttgatgtca tactttttca
    21661 ggattggaaa agcaacgttg taaaaatcaa ccatgctatc atcaaaggtt agccagacaa
    21721 ccttttcagc aggaagctcg ttagctgata agactcggta ggcttcttcg ggagataaaa
    21781 agtagtagcc ggcctccttc attgccttta gctggctttc aaaaagatct ggagcaacga
    21841 tgagattggc acttgctgcc tcttctggtg ccataacgtg aatagcatga tacattaaga
    21901 taggaagctt aacagggttt tgctgcttgg tccagctgac agctcctttt tgctgctgac
    21961 tatttgtatg gctagcttcc ttattagttg cttttttgct aggcttggga gctggttttt
    22021 tatcagtttt tgaaaatagg cttattttgg ggattgcctg cgataattga gagatgctta
    22081 tctttgaatg gctcttgtaa aggtagacaa tagctgataa gcctatgata caggcaagta
    22141 gtagcatgag attaatcatt ttgaagattt ttcttttctt acgccgtttg tttctgttgt
    22201 tcatcacttg ctccttgttt attgattagt ctattgtaac atttttttaa gtaagctgtc
    22261 tttcgttaac ttaatttttt gctaacattc tattagtgtt atgctttgta aaacaagacc
    22321 tagatttgct ataataagac agagtattta agacagtcaa aaaaaggagg ataggatgtc
    22381 agttaaggtt gcattattag gctttgggac tgttgctagt ggcattccct tgctattaga
    22441 aaacaatagt agcaagattc gtgcagtggt aggtgatgat ttggtgattg caaaggttct
    22501 ggttagagat gagaccacta agaagcgttt gttggatcaa ggctattcct accaatttgt
    22561 gacctccatt gatgatattg ttgatgatga gagcattgat atggtggtcg aattaatggg
    22621 tcgtatcgag cctgcaaaga cctttatctc gcgtgctcta tcagccggaa agcctgttgt
    22681 gactgctaat aaggatttga tagccttgta cggaggagag ctctcgactt tggcagctaa
    22741 gcatcaggta gctttgtact acgaggctgc tgttgctggt ggtattccaa tactaagagc
    22801 tttggctgat tcctttgcct cagataagct gacgcgtctg ctcggtgtgc tcaatggaac
    22861 aactaatttc atgttaacca agatgattga tgagggctgg acctatgaaa gggccctgca
    22921 aaaagcgcag gagctgggct atgctgaaag tgatccgact aatgatgtga aagggatcga
    22981 tgcagcttac aaggttgcta ttcttagtca gtttgctttt ggaatgacca ttgactttga
    23041 ggctattagc tattcaggga ttgataaggt tcgagtagaa gatgtgacag tagcgcagaa
    23101 gctgggctat gtgatcaaat tagttggtct acttgaagag acggcttctg ggcttaacgc
    23161 agaggtatcc ccagtctttt taccaaagac acacccgttg gctgctgtag acggtgtgat
    23221 gaatgctgtt tatatcgagt caattggggt tgggcaggct atgttttatg gtccaggtgc
    23281 cggtcaaatg ccaacagcta cagctgttgt ggcagatatg attcagactg cctgcacctt
    23341 acgtgaccat acagtctcag tctttaatcg ttttgctaca aaaactagac tagctaagtc
    23401 tgaggatatt atgagtccct attactttgc tattcaagca actaataagt ttggtcagct
    23461 actagagcta acaaggctat gtgatgtttg tggcattaga gttgagcagc tgttatcaga
    23521 tgagatagat agtgacaggt tagactttgt gatgattact catgagatga gcaaaaagga
    23581 gcttgcttgc tttacagcgc tactacagga tcatcaggat ttccgtatgt taagtacatt
    23641 taagatttta ggagattgac atgaagatac gcgtacctgc aacctcggct aatttgggac
    23701 ctggatttga ctcaatgggg attgctgttt caaaatacct agaagttgac attttagaag
    23761 aacgtgacca atggtttatt gagcatgatt tgggtgatat tccaaatgat gatagcaact
    23821 tacttatcca aacagccctt aggctagcac caaatattcc agcacatcgt ctaaagatga
    23881 cgtctgatat tccattggca cgtggcttgg gatcgtcctc ctcggtgatt gtcgctggta
    23941 ttgaattagc taatcagcta gggcatttaa acctaacaga cgaccgtaaa ttggccatag
    24001 caactcgtat tgaggggcac cctgataatg tagctccagc gatttttggt caattggtaa
    24061 ttgcttcaca gattggtaag gacgtggatt acatcattgc gccttttcct gacctttctt
    24121 tggtttgttt tattcctgat tatgagctga aaacctctga ttccagagat gtattgccca
    24181 agcagctatc gtataagcag gcagtggctg cttcctcagt tgctaatctt gctatagctg
    24241 cgctattgac cggtaatttg aaaaaggccg gtcgggcgat tgaaaatgac caattccacg
    24301 aaatctaccg gcaaagatta gtcagagagt tccagccgat taagcgagct gcagcagcta
    24361 atggtgctta tgcaacctac ttatccggtg cagggcctgc tattatggtt atgtgtccca
    24421 ataagaaaaa aatggcgatt tatgaggcca tcgagcagct aggtctaatt ggtcagttgg
    24481 tgtctctaga gctggatcgt caggggctgt gtcttgtcta gactggcaag gtactggtat
    24541 gcttgcctag taggcttatt gttgatatca gatggactta aagcttagtc attcaaatac
    24601 atcaaaaaag tgaggcttga tcgttttatc ggctttcact tttttcttga tatgttatac
    24661 tagagtagac tttgtgaggt gtgtgatgaa ttatcaagaa acattagact ggattcatgg
    24721 tcaggaaaga tttgggatca agccaggtgt aaaacgcatg cgttgggtgc ttgagcagct
    24781 aggtaatcct caagatagga ttagaggaat ccatgtggtc ggcacaaatg gtaagggatc
    24841 gacggtcaat gacctacagc atatttttac tagagcaggc tatgaggttg gaacctttac
    24901 ctcgccttat atcatggatt ttaaggaacg tatctgtctc aatggtgaga tgatctcaga
    24961 gactgacctt gttaaggctg ctaattgtat tcgtccacta acggatcgcc ttatcagtga
    25021 gacaagtttg ggtcctgcaa cagtctttga gctgatcact ctgatcatgt ttctttattt
    25081 tggtgagagt cacccggttg atattgctat tatcgaggca ggattagggg ggctttatga
    25141 ctccactaat gtgtttcagg cgatggctgt ggtttgcccg tctattggtc ttgatcatca
    25201 agctatttta ggtgatacct atgctgacat tgcctatcaa aaagccggtg tgctaaaggg
    25261 tggtgaagac cttatttttg ccattgataa caaagaggcc agacaggttt ttctaaaaaa
    25321 agcagagcag cttggcgtgc ctatttggga atggcgtcga cagttcaaca tgctacaggg
    25381 tgaaggtggt tatcaattta acagtcagct tggtcagctg tctcatctag tgcttgcaat
    25441 gcctggtcag catcaggtag ccaatgcagg cctagccact atgacaagct tgatattaca
    25501 ggatcggtac ccaaaggtaa ctgagtctgt tattagagag gctctggcaa gcagcttttg
    25561 gttgggacga acagaattgt tggcacccaa cctgatgatt gatggtgctc ataataatga
    25621 aagcattgcc gccctgattg atgtgatatc atcagactat caggataagc agattcatat
    25681 tctatttggt gccattgata ccaagcctgt ctcagatatg ctgcagagtc tggagcgtct
    25741 tggagatgtg caagtaacaa gctttcacta tcccaatgcc tatcctttgg aggcttatcc
    25801 agataggcta acaaaagtag cagattttag agcattttta gaccggcttg agcaagcagc
    25861 tgctgatgat tttttcctga ttacaggctc tctttacttc atctcagagg tcaggcagta
    25921 ttggaaaaag gtattaagca agtaatgctt tctcacatca actcatcaaa caagattaat
    25981 caactaaaaa ggggaaaacc attgccaatc aatcaaaaaa aagcagaagc cgctatctat
    26041 caattattag aagctatcgg tgaggatcca aaccgagaag ggctacgaga taccccaaag
    26101 cgtgttgcca agatgtatct agaaatgctc tcagggctgg aacaggacgc taaggatgaa
    26161 tttacagctg tttttacaga gcatcacgac gatttggtga ttgttaagga tattagcttt
    26221 tattccatgt gtgagcacca tctggtgcca ttttatggta aggcgcatat tgcttatttg
    26281 cctagtgatg ggcgtgtgac aggcttgagt aagctggcaa gggcagttga ggtgacgagc
    26341 aaaagacctc agctgcagga gcgtttgaca gctcagattg ctaatgctct tgttgatgcc
    26401 ttgcagccca aaggggtttt tgttatggta gaagcagagc atatgtgcat gaccatgcga
    26461 ggtgtcaaaa agccaggcag taagaccatt acgacaactg ctagagggat ttacaaggat
    26521 agtagagacg acaggcgtga ggttatgcaa ttaatcatgg agggctaggg tatttatgac
    26581 tattggacat tattcagccg ctggtgaggc agctattatg gggattttaa atgtgactcc
    26641 ggattcgttt tcagatggtg gctcctatac tagtgttaat caggccttgg cacaggccga
    26701 aaaaatgctg tcagaaggag cgactgtcat tgatattgga ggcgagtcaa cacgaccggg
    26761 ctgccaattt gtgccggcag aagaagagat tgcacgcgtt gttccaatca taaaggccat
    26821 taaaaaacgg tatgatgtcc ttattagcat tgatacctac aagacagaaa ctgctagagc
    26881 ggcccttgaa gcaggagcag atatgctcaa tgatgtctgg gcaggactat atgacggtca
    26941 aatgctaagt ctagccgccg aatacgacgt tcccattata ttaatgcata atcaaaccaa
    27001 agaggcttat gctgatgtta caaaagaggt ttgcagcttt ttacaggcta gagcagctgc
    27061 agccctcaaa gcaggtgtca aaaaagaaca tatctggctt gatccaggat ttggctttgc
    27121 taaaaatgtt gagcaaaata tagccttatt aaaagggcta aatgaggttt gccagttggg
    27181 ctatcctgtt ctttttggga tttccagaaa gcgtgttgta gacgccctac ttggtggcgg
    27241 cactaaagcc aaggatcgtg acggggctac tgccgcccta tcagcctacg ctattaataa
    27301 ggggtgtcaa atggtgcgcg tgcataatgt cggtgctaac agggatattg tctctgtatt
    27361 gagtcaatta aggtgagaaa tgatggataa aatcagatta gaggcttgtc gcttttatgg
    27421 ttatcatggt gcctttaagg aggagcaggt cttaggtcaa atttttgtag tggatttaga
    27481 attatcagtt gacttgatgg ctgcctctct ttcagactgc ctagaggata ctgttcatta
    27541 tggtttagtt tttgaaacag tccgtcaaat tgttgaggaa aagaccttta cgcttatcga
    27601 acgtttggct ggtgccattt gtcaagagct atttgcccag tttttgccta ttaaagcgat
    27661 taaaatcgct attaaaaaag aaaatccacc gattgcaggc cattatcaag ctgtcggtat
    27721 tgaattggag agaaagagat gacacttgtt tatttaggct tgggaactaa tatgggagat
    27781 agggcaggct acctacaggc agcagttaat gccctatcta agctgccaga gactgagtta
    27841 ctgagacaat cctctatcta tcaaacagca gcctggggaa aaacagatca aaatgccttt
    27901 ttgaatatgg cttgccagct agatactagg ctgacatcag aagctctttt ggcagctacg
    27961 caggctatcg agcaggctct gggacgagtt cgtcatgaaa aatggggccc aaggacaatt
    28021 gatattgacc tcttgctgtt tggtgatgag ccgtatcaat cagagacctt ggttattcct
    28081 cacccttaca tgacacaaag agcctttgtt ttgattcctt tattagagat tgcacccgat
    28141 gtgaccttac ctggtagcca gaaaagcctg aggtcttacc ttgatgcttt agagcaatca
    28201 gatgtagcct tgtggtcaca tgagtattca aataagtttt cttaaactgt cgttattttt
    28261 actaaaattt gatataatag tgctactctt tgctgatttt ttgtcttata ttaagaaatg
    28321 attgaagaaa gaagaagatt atgatagctg aacttgaagg cattgatatt cgagagaatg
    28381 aagccttaaa acattacacc tatacccaag taggcggtcc agcagatttc ttggcttttc
    28441 ctagaaatca ttacgaacta tcccgtattg ttgattatgc caatcataat catattcctt
    28501 ggatggtcct tggaaatgcc agtaatctca ttgttcgaga cggtggtatt cgtggctttg
    28561 ttatcatgtt tgataagctc aacgccgtcc gccttaatgg ttataccttg gaggcagagg
    28621 caggcgctaa cctcattgaa acaacaaaag ttgccaaatt tcatagctta acaggctttg
    28681 aatttgcttg tggcattcct ggaagcatag ggggtgctgt ttttatgaat gcaggtgctt
    28741 atggtggaga gattgctcat atttttttgt cggccaaggt cttgacacca gaagggaaaa
    28801 taaaaaagat ctcagccaga gagatggcct ttggctatcg tcactctgtc attcaagaaa
    28861 ctggtgatat tgtgatttca gccaagtttg ctttaaaacc gggtaatcat gacagtattt
    28921 gtcaggagat gaatcgcctc aaccaccttc gaaagctcaa gcagccctta gaatttccct
    28981 cttgtgggtc cgtttttaag cgtcctcctg ggcattttgc agggcaattg attatggacg
    29041 ctaacctaaa agggcatcgt gttggcggtg ttgaggtctc taaaaagcat gcaggcttta
    29101 tgattaatgt tgctgatggc tctgccaagg attatgagga cttaattgct catgtcatta
    29161 ggacagttga gcaggcatct ggcgttaggc ttgagccgga ggttcgtatt attggtgaaa
    29221 gcctttaatg attgtgttat caaaaaagaa aaattgtgga ggatttatga caattgacta
    29281 agccaattat cacatttgac aatgtctcaa agacatttga ggacagcggg acacaggtcc
    29341 taaagaacat taattttgag cttgaggagg gaaaatttta caccctgctt ggtgcctcag
    29401 gatctgggaa atcaaccatt ttaaatatta tggctgggct gcttgatgcg accagtggtg
    29461 atatttattt agatggtgag cgtatcaatg atttgccgac caataagcgt gatattcaca
    29521 ctgtttttca gaattatgct ttgtttcctc atatgacggt ttttgagaac gttgcctttg
    29581 ctttaaagct gaaaaaggtt gacaaacagg agatagcaag acgtgtcaag gaaaccttaa
    29641 aaatggttca gctggagggc tacgaaaagc gatccattca aaagctttcc ggtggtcagc
    29701 gtcagcgtgt agcgattgct cgtgcgatta tcaatcagcc tcgtcttgtc ctattagatg
    29761 agccactttc tgcccttgat ttgaaattga gaacagaaat gcagtatgag ctgcgtgagc
    29821 tgcagcagcg actgggcatt acctttgttt ttgttaccca tgatcaggaa gaagcactag
    29881 cgatgagtga ttggattttt gtcatgaatg atggtgaaat tgtgcaatca ggcacacctg
    29941 tagatattta cgatgagccg attaatcatt ttgtagctag ctttattggt gaatcaaaca
    30001 tcatcaatgg tacgatgatt aaagactatc tggtttcctt taacgggaaa gaatttgagt
    30061 cagttgatgg tggtatgcga cccaatgagc cagttgaggt ggttattcga ccggaggatt
    30121 tacaaatcac cctgccagag gaaggaaagc ttcaggtaaa ggtagataca cagctctttc
    30181 gtggtgttca ctatgaaatc attgcctatg atgatttagg caacgaatgg atgattcact
    30241 caacccgcaa ggccattgaa ggagaagtga ttggtttaga tttcacacca gaggatattc
    30301 atattatgcg cctcaatgaa acagaagaag aatttgatgc tcgtatcgaa gaatacgttg
    30361 aaatcgatga gcatgcggat ggcttaatca atgctattga ggaggagcgc aatgaagaaa
    30421 acctctagcc tctttgcagt tccctatttt ttatggattg tcctctttgt tatggcaccg
    30481 gttgcccttt tgctttatca atcctttttt gacatcgaag gacgattgac actagccaat
    30541 tacgagactt tttttagctc atggacttac ctgagaatgg gcttaaactc tatcttatat
    30601 gctggtatcg ttaccttggt gacctttttg atttcatatc ccacagcttt attgttaacg
    30661 cgtttaaagc acaagcagct gtggttaatg cttattattt taccaacctg ggtcaatctg
    30721 ctcctcaagg cttatgcttt tatggggatt tttgggcagc agggtggtat caatagcttt
    30781 ttaaccttta tgggcttagg accacagcaa attctgttta ctgatttttc gtttattttt
    30841 gtggcctctt atattgagct gccctttatg attttgccta tttttaatgc tttagatgat
    30901 attgatgata atattatcaa tgccagtaag gacctgggtg ccaatgacta ccagaccttt
    30961 tcaagggtta tctttccttt gtcgctaaac ggtgttagag caggggttca gtctgttttt
    31021 attcccagct tgagtctctt tatgcttacg cgtctcatcg gtggaaatcg tgtgattacg
    31081 ctggggacag ctattgaaca gcatttccta acaacagaaa actggggcat gggctcaacc
    31141 ataggtgttg tcctaattat cgcgatgatt gtgattatgt ggctaacaaa ggagaaaagt
    31201 aaatgaaaaa atttgccaat ctttacttag cgtgtgtttt tattttgctc tatattccaa
    31261 tcttttactt gattgtttat tcttttaaca agggtggaga catgaatggc ttttctggct
    31321 tgacgctaga gcattataag accatgtttg atgatagtcg cttgatggcg attttattgc
    31381 agacctttgt gttagccttt acaagtgcct tgcttgcaac cattatcggg acctttgggg
    31441 cgatttttat tcatcagagt aaaaagaagt accaaaatgc gatactgtct gcaaataatg
    31501 tgttgatggt ttcccctgat gtgatgatag gtgcctcttt cttgattctc tttacgtcct
    31561 tgaaatttca attaggaatc ctctcggttt tgatgagtca tattgctttt tccattccga
    31621 ttgtggtctt aatggtgctt cctcggttga aggaaatgaa tcaagatatg attaatgcag
    31681 cttatgatct aggagcaaat cactttcaaa tgctaaagga ggttatgctt ccttatctga
    31741 caccgggcat tatcgcaggc tactttatgg cctttactta ttccttagat gattttgcgg
    31801 tgaccttttt tctaacagga aatggcttta caaccctgtc tgttgagatc tattcgcgtg
    31861 ctcgaagggg tatttcatta gatatcaatg ccttatcaac gattgtcttt ttgttctcaa
    31921 ttctattagt cattggctat tattacattt cacaggacaa ggaggaaaag catgcgtaag
    31981 ctatactctt ttttagcggg aattatcggg gttatcttgc tgcttgcgac cctgtccttt
    32041 attttgcaga aaaaaacgag ctctgctagt caatctgata agctggtgat ttataactgg
    32101 ggtgattaca ttgatcccgc tttgctgaaa aaattcacta aggaaaccgg tatcgaggtt
    32161 cagtatgaga cctttgattc caatgaagcc atgtacacca agatcaaaca gggtggaacg
    32221 acctatgaca ttgctgttcc gagtgattac acgattgaca agatgattaa ggaaaagctt
    32281 cttgttaagc tagataagtc caagcttgtt ggtctagata acattggtca ggagttttta
    32341 ggaaaaagct ttgatccgca caatgattat tccattcctt atttttgggg aacggtaggc
    32401 attgtctata atgaccagct ggtggataag gctcctatgc attgggagga tttatggcgg
    32461 ccagaatacc aaaatagtat catgctagtt gatggtgctc gtgagatttt aggtgttgga
    32521 ttgaccacat ttggctatag cgttaactca aagcacctaa agcagcttga agcagctgaa
    32581 aaaaaactac aggccttaac ccctaatgta aaagcaatcg tcgctgacga gatgaagggg
    32641 tatatgattc agggtgacgc tgctattggt gttaccttct caggagaggc tagcgaaatg
    32701 ctggacaata acgaccatct acactatgtt gtaccatcag agggctcaaa cctttggttt
    32761 gataatctgg tgcttcccaa aacaatgaag catgaaaatg aagcctatgc ctttatcaac
    32821 tttatcatga agccggaaaa tgcagcacaa aatgctgaat atatcggcta tgccactccc
    32881 aatacaaaag cgaaggcttt attgccagat gatattaaaa atgacccagc cttttaccca
    32941 actgacgaga ccgtaaagaa attagaggtt tatgataatt taggctctaa atggcttggt
    33001 atttacaacg acctttacct acaatttaag atgtatcgaa aataggtcat gcaagattga
    33061 aggagctatt cattggaaag cttcttcagt cttttttagc ttggtctggt ctcaataatc
    33121 tcatgagatt aaaaagaact agaatcttgc tttcgtcttt gatacaatag tagtggttta
    33181 ttaaaatgaa agagatgaca aaatggaaaa tcataaaaac gagtttacct tttccaaaca
    33241 ttcaatcata gcctacgttt ggcgtggcat tttagtcggg ataattgctg gagctattgt
    33301 cagtttgttt cgcttattga ttgagatggt tagtgaggct gttgttggct attatcacca
    33361 agctcacagc aatcgcatgc tccttgttcc gatagcaggc tttagcttat tagctgtttt
    33421 tttagttggt cttttggtca agtctgacgc caacattaaa ggctctggta ttccacacgt
    33481 cgaaggggag ctaaagggct tgatgtcacc caattggtgg agtgtgcttt ggaaaaaata
    33541 ccttggtgga acaattgcca tttctatggg cttaatgctt ggaagagaag gcccttctat
    33601 acaattaggg gctatgtcag ctaaaggctt agctaagtac ctgaaatcta gtcgtctaga
    33661 aaaacgtgtc ttgatcgcta gtggagcagc tgctggctta tcagctgctt ttaatgcgcc
    33721 tattgcagga ctgctttttg ttgttgagga gatttaccac catttttcaa gattagtgtg
    33781 gatcactgcc ttggttgcaa gccttgttgc gaactttatt tcgttgaata tttttggcct
    33841 tagacctgtt ttggccatgc ctaaggccat gccctttctt gccttacatc aatattggct
    33901 gctcttaatc ttaggccttg tgcttggctg tctgggcttt ctttatgaag aggtcatttt
    33961 acattttcat agggtttatg attttcttgg aaagagcttg cgcctagcgc cgcattttca
    34021 tgggctgatt gttgttgcta ttatcctgct gattggctat tatttgccac agctattggg
    34081 cggaggtcat ggtttgatta tgtccttgtc agagcaaaag ctaccactgt tgactgttct
    34141 tgcttacttc tttattcgat ttttagggag tatgtttagc tatggcagtg gcctgcctgg
    34201 aggaattttt ttgcctattc taaccttagg tgccttgtcc ggaactattt ttggattgat
    34261 tcttcagcaa ataggactgt tagatcgcca gatgattcct ctctttttag tattgggaat
    34321 ggcaggctac tttgctgctg tatcaaaggc acccttgaca ggaatgatct tagtgactga
    34381 aatggtaggg gatctgaagc ccttaatggc cattgctgtt gtgaccttcg tggcctactt
    34441 ggtgatggat ttgttaaatg gtcagcctat ctatgaagca atgctagaga aaatggctat
    34501 caaacaccca acagatctag tggagccgac cctgatcgaa ttacctgtaa gtgagaaaat
    34561 tgcaggcaga tatgtccgag acctgaagct acctaaaaac gttttaatta caacgcagct
    34621 ccaccataag aaatcacagg tcgtctcagg tgatacgcta ttgatttcag gtgctacgat
    34681 ctttttggtg gtcaatgaag ctgatacagg ctttgttcga gaggtcttga tgtagagcaa
    34741 ggtcggttaa gcagtcagca gtagctgtgc taccgatcaa agaagcagat cagtgctttt
    34801 tctcatctga tgaaaggtat tgatttgctt tttttgtgtt attaaacctt tgttagcaag
    34861 agccatagcc ttagcagtcg tatctgatga atacctgctg tctttttgtt atacttaagt
    34921 atcaatcaaa ggagctttat atgctagaag ttatttcaaa agagctgcgc cattaccaaa
    34981 agaataagct tgccgcctat caaaaaaaga accaaggcat agaagctggt ggaattgttt
    35041 ttgctggcga ttcgttaatc gaatttttcc cgttgaaaaa atatttcaaa caggtctcaa
    35101 ccatttataa tcgcggaatt gcagggatag acagtcagtg gttgctagag catattgaca
    35161 gtcatgtgaa tgatctggag cccagtcatg tgtttatcct gattggctgt aatgatattg
    35221 ggcttggctt tgatcaatcg catatcgtat cgaccattgt tgatcttatt agtcgtattc
    35281 gcagtcagtc tatttatact aggattagcc ttctgtcctt attgccggtt tctgaaaatc
    35341 ccgcctatca ggcgactgtc aagctaagga caaatagggc tattgatgag attaatcaag
    35401 cattagcaat gataccagcg attgaattta ttgatcttaa cgcctgctta aaggacgaga
    35461 ctggtggctt agcagctgct tatacggtag atggcattca tcttaatgcc cttggctatg
    35521 aacacttagc tcaagctatt agtccctatc tatgaaaggt aaaggctgga gctgctaatt
    35581 tgtaagggat ctttaaaaaa caagcactga tgaatcatca ttgaaaccct tcagagtgcc
    35641 gataggctgc acaatcaaag aagcattagg tttgtctatg acgcccttgt gttaagctgg
    35701 cttttaggtt tatactgcga gaaaatcagt cattgggctg ggagtctcaa agcttagctg
    35761 tggtaattaa atgcgagctc ctgctagctt gtgctgatca agcagtatag caaggaggga
    35821 ctgaactttt agtctcagat aatattagac tttttatcct atattaaacg atttagtgta
    35881 taataaacag gaaggagtta aaatgaaatt tgaaaaaaaa caagtctttt atgttgtgct
    35941 tgcctttgtg ctttgttatg ctattcaagc taattgggat aatggggcta atattgtcac
    36001 aaccgtttat aagacaagcc tgccctttct ttatggagca gcagtcgcct atattgttaa
    36061 tattgtcatg agtgcctatg aaagagctta tacttatacc ctaaaaccct ttccttttgc
    36121 catgaaggct agaagagggc tctgtatgct tttggcatat tttaccttta tcagcttgat
    36181 cgtatggatt atttctattg taatccctga tttgattgca agcattagct cgttaacgca
    36241 atttgataca agagctatca aggaggtcat cagtgattta ggtcacaata agctgattgc
    36301 acgtgccatt aattacattg gtggagatgc taagctgaca gaaacaatta ccaattatag
    36361 ccagcagctg ctcaagcaat ttataggtgt tctaaccggt attttgacat cggttacagc
    36421 agttgcctca gccattatca atgtggttat cagctttgtc ttttccctgt atgtgcttgc
    36481 tagcaaggaa gagctttgtc agcaggcaac taccttaatt gacacctata ctggtaaata
    36541 cgcaaaggcc attcattatt tagtgggttt gctgcatagt cgttttcgtg gcttctttgt
    36601 gagtcagacg cttgaagcaa tgattttagg ctccttgact gccattggca tgtttatcct
    36661 gcaattaccc tttgcaggaa ctattggagt cttggttgct tttactgcct tgatccctgt
    36721 tgttggtgct tcaatcggtg ctgcgatagg ctttgttttg attatgactc agtcaatgtc
    36781 gcaggcagtc gtctttattg tctttcttgt tatactacag caaatcgagg ggaattttat
    36841 ttatcccaga gtggttggtg ggtctatcgg gttaccagct atgtgggtct taatggcaat
    36901 caccattggt gctgctctca aaggcattgt tggtatgatc gttgcagtgc cattagcggc
    36961 aacgctttat caagtggtaa aggatcacat tcataaaaag caggccttac aaaatcgtca
    37021 gtccagctaa ttaacagcat cagatcaagg aaaacgtcta ttacaagacc gatttcttgg
    37081 tcttttatgc tgtctgattg actgcgtatg gccttatttt tatgctgtgg taatgaaaaa
    37141 agccgtctta tttatcgaat atcattagtg gaggtaataa gatgtattcc atcaaaactg
    37201 atcataaatt aatgcctaga gagcgtttga ttcgactggg tccagaaaag ctaagcaatc
    37261 aagagcaact agcgatccta cttaggacag gtaacaagga aaagcatgtc ttagagttgt
    37321 ctgcttattt attgtcaagc ttagatagtc tagctgactt gaagaaattt tctttacaag
    37381 aactacagcg cttatccggg ataggaaagg tcaaggctat tgagattaag gccatgctgg
    37441 agctggcaga ccgtattcag atagcgggac aagcagtagc agatcctgtc ttatctagtg
    37501 ctcaggtggc tgaaaagatg atgattgaat taggagacaa gcagcaggag catttagtcg
    37561 ctatttatct cgatagtcaa aataaaatca ttgaagaaaa gacgatattt ataggaaccg
    37621 tcagaaaatc aattgcagag cctagagaaa ttctttatta tgcgtgtaaa aatatggcga
    37681 ctagccttat tgttgttcac aatcatccct caggcctgac caagccaagc gcaaatgact
    37741 atcacttcac agaaaaaata aaacgatcat gtgattattt aggacttatc tgcctagatc
    37801 acattatcgt tagtaagtat gactactata gctttcggga aaaatcagat ttattttgag
    37861 ttagaaacta tggataaacc aatcaaagag ccttaggtct tcttctctaa tagcctgaag
    37921 cagctctggg tgccactgga caccgagaaa gggaatatca ggattgcagg agataacagc
    37981 ctcgatggtg ccatcgttag gatcccttgc aatcactctt aagtcctctg cgacctgctt
    38041 taggctctgg tggtgaaatg aattaatcag cgctcttgga ccatagatag ggtacaaagg
    38101 tgaagtcttt tcgatcacta tctcctgtga taaacagtca gaggcagtct tttgccaatg
    38161 gccctcaatg tgctggttta gactgccacc tagagcaaca tttattaact gcataccgcg
    38221 acaaatccct aaaattggtt ttttctgcgc tagggcttct ttaatgatgg ctagctcaaa
    38281 gatgtcacgc tggggtgaaa aatcaccatc aagtgcagct cttttttcat gataatattt
    38341 aggatcaaca tgctgaccac caataagaat gattttatca accattgcga cataggattt
    38401 ggcagccgcc tcatccccaa tcggaagaag taagggtagg ccaccagatc ttgtcacagc
    38461 ctcgatgaag cttgttggag cataggagca aggcaggtta tctagagcct tggtccccct
    38521 ttggttagca gttatcccaa taattgtttt agacacgacc ttctccatta atcaagatga
    38581 ttttggttca taaagtatag caaggtttgc aactcgctgg tcaaatcaac agattggacg
    38641 atcacacctt ttggaacctg taagtgaagt ggagcaaagc ttaaaatacc gcgaatgcca
    38701 gcttcaatca gttgatctgc aacctcttga gcatagatgc ttgggactgt tagaatagcc
    38761 gtttcaatgc ctgaattatc caggtgctcc ttaatggtag aaatgccata aataggaata
    38821 tcatcaggcg ttttggtgcc gaccatagga ttatcatcag tgtcaaatcc cataacaatc
    38881 tgcattttgt ttcgatcgtg gaagcggtag tgaagaagtg cacgaccaat attgccgcag
    38941 ccaactaaaa tcacatgcgt tgttgagtga tcatttagca aatctgcaaa aaaattcatt
    39001 aattttgtga catcatagcc aaatccacgt cggcctaatt caccaaagta agaaaaatca
    39061 cgtcgaacag ttgcagaatc aattcccata gcatcagcaa tctgttttga gcttgccttt
    39121 tcaacctgat cagcataaaa gcgtttaaaa atacgataat agagtgataa gcgttttgca
    39181 gtcgcttttg gaatagattt atcaataacc acttttgtag ctccttctat tgttatttta
    39241 atgttatcta tcaccattgt agcagataga ttgtgaaata tgcaactatt tgaccattct
    39301 ttttgtgttt ttcgttataa aatgacttga cagcacaagc attggtattt ttcaaaccca
    39361 gtcacctcga gtataaaaaa gcagacaatg aagcacttgc cctttaggtc agctgcgatg
    39421 gctgggcttg tcttgttaaa ggcaaatgta ctgtcattgt ctgatatttc tctgagatta
    39481 gaagagctct tgtgtgctta gcattctttt ttaatgaaaa tatcacgctc aacaaggcta
    39541 tccattaaaa agtaaaactt gtcctgtagt atgctatgct cttcagattt aaaaatgttc
    39601 accagtctta gaccggattg gtctgttata gctagcttaa agccatctaa atctttatta
    39661 atcgtaattt ttaaagggaa gccctcaccc gaattaggga ctttttccag tagtcgtgtt
    39721 aactgatagt gaccaatctt ggtctgacta aaggttgtgt ctcttagggt gtatttttta
    39781 atctttgggc taatcctgta gctgtatttg cagtctttaa gggcaatttc tttttcaaat
    39841 gccatatgat cctcctaaaa tatttttgag ctgggttgct agtgcgataa cgtctttttg
    39901 agtattttgc tctgaaaagc taactcgaat agcttctgtg agacgatggg actgcttgcc
    39961 gaaataagct gccaaaacgt gacttggctc aacagcacca gctgtacaag cagagcctga
    40021 cgacacagca aagcctgcta aatcaagctg agtcagtaat acatgatttt ggtaaccagg
    40081 aaagccgata ttaatgatat agggaagatg acactcatta tgattgagct gataagaaat
    40141 accttctaat tcactaagca agagctgtga tagctcttta gcatgctggt aatgctgtgg
    40201 cagccttgag acagcctcat ctaatgcttg ggtcatgccg acgatattaa tcaggctttc
    40261 agtgccggct ctttgtttgt tttcttgatt gccgccatgt aagagggggg ccaactttaa
    40321 gcctttattg tataaaaaac cagtcccctt tggtccatga aacttatggg cagaggcaga
    40381 gagcaaatca atccccaaat ctgccggctg tattgggacc ttgccaatag cttggacagc
    40441 atcaacatga aagacagcct gatgctgctt tagcatgcta ccaacagcct gaataggcag
    40501 caaatctccc gtttcgttgt tagcaaacat catgctgact aagattgtat cctctcttaa
    40561 ggcagcttgg agctgattta gatcaatgat tccattttta gcctcaaggt aggtcacctc
    40621 aaagccaaat cgttcttcca gataggccat tgtgcttaac acggaatgat gctcaatagc
    40681 agttgtaatc aagtgtttgc ctttttcctg atgagctaag gcatagccct tgatagcagt
    40741 attgttactt tcagtacctc ctgaggtaaa gataatgtgg ttttctgcag ctcctaggca
    40801 gttggcaata gcttttcggc actctcttaa ttgtttgttt gcctgccgcc cataagcatg
    40861 aatactagat gggttaccaa aatcatcagc catagcttca gtcatcgcct tgatagcagc
    40921 ctgactaagc gatgttgtag cagcattatc aaaataaatc atgattagtt agtgctttca
    40981 ggtttgtaag aaaacagtgg acttagtggt tttctttcgt gaatgcgaat gatagcctct
    41041 gcaattaaat cactggcact aagataggtt actgttttag ggatacgatt tttagtcttg
    41101 acagagtccg tgacaatgat ctctttgatt ggagcagtct ctaaaatatc agctgcacct
    41161 cctgcaaaaa tcccatgact agccactgca taaatgtcag ttgcgcctgc acattctagg
    41221 atcttagctg cctctgcaaa ggtttttcct gtgttgagaa tgtcatcaat caagatagcc
    41281 ttcttgccag caacatcacc aatcacatag ccttcttcgc gctcagcatc gtcttgtgca
    41341 taatcgataa tggcaattgg agagttaaga tactctgcta agcttctagc acgcttgata
    41401 ccagaatttt tagggctgac aataaccgta tcaggtcctg agaggcccag tggataatag
    41461 tgctttgcaa aaagaggcac tgtaaataaa ttatcaactg gaatgtcaaa aaagccttgg
    41521 acctgaaccg catgcaaatc aagggttaca acgcgatcaa tccctgcttt ggtcagcatg
    41581 tttgcgacca gctttgctgt aataggctcg cgagactttg caacacgatc ctgacgcgaa
    41641 taaccaaaat atggcaaaac aatattgact gtattagcac ttgcacgctt acaagcatca
    41701 atcatgatga gcagctccca taggttatcg ttgacaggaa agcttgttga ttgaatgata
    41761 taaatatcat caccacgaac tgtttcttca atgttaatca tgatctcacc atcagaaaat
    41821 tgacgagatg agacctttcc aagcggaata ccagcagcct tagaaatttt ttcagcgatt
    41881 gcgagatttg aagtgagtga gaacagcttg atttgcttgt cagcatatcg ttcagtcatg
    41941 ataaaattag ctccttacat tacattaacg atagaataac aggttaacag ttattcaaga
    42001 ttacaaatag acagtactat tttaacaaaa aaacagaaaa atttcagtct ttctgttgat
    42061 tttctgtcct ctcctaggat tttttaaggg tcttgctaaa gcgagcgacc ttgcttttgg
    42121 aatatttaaa ggtgatctga tgctgggcta aaaagtggtc aaaatcaacc tttcctctta
    42181 caggatcagt cacctctagc tcaagctcat agtctttgat accagcatat tgattataat
    42241 ccagcgctag cttgccaata ggagtatctg cctctcgacg aatggtagtc aggtttccga
    42301 aggtttttat agcagatagg tcaacgtcaa gagtgctgat aatatcaagg atagctgatt
    42361 ttggtagctg tcctgtctga atgatagctt ttgcttgggt gtcatcaagc tctaaattgt
    42421 actcgcgatt accaaccttt tcagggactt ttaaggttaa ttcagcagga gcagcaacaa
    42481 aggtgcgaat gcgaagtgac attttatgag ccttgagatc aaaatgatca gtatcaatgt
    42541 aataatttgt ctgggtaact ggtgggacat gagtcatttg agagaggagg cgattatatt
    42601 cgtcctttgt cagtaaggtc ttgtattcga tttctaggtt agtcatgcga acgttccttt
    42661 taactatatt ttatgctata ataaattgtt atcttaattt tatattaata tccgaggttt
    42721 gacaagaaag gagagaaagg atggctttag attgggaaga atttttggat ccttatatac
    42781 aaacggttgg cgaattgaaa attaagctgc gcggtatccg aaagcagttt cgcaagcaaa
    42841 accgttattc tcctattgag tttgtgactg gacgtgtcaa gtcggttgag agcatcaagg
    42901 aaaaaatggc cttgcgtggt gtcttggaag aaaatatcgc tcaagatatt caagacatcg
    42961 ctgggcttag gattatggtg cagtttgtgg acgatattga ggacgttttg tccttgctta
    43021 gacaaagaca ggacatgaca attgtttatg agcgagacta cattagaaac atgaaatcta
    43081 gtggttatcg ctcgtatcat gttgtcgttg agtatcctgt tgataccatt gagggtcaaa
    43141 aaaaagtatt agcagaaatt caaatccgta ctttagcaat gaatttttgg gcaaccattg
    43201 agcattcctt gaactacaag tacggtggtg attttccaga agaaataaaa aaacgattag
    43261 aggttacagc aaaaattgct ttggagcttg atgaagaaat gcgaaaaatt cgtgaagaca
    43321 ttcgtgaagc acaattgtta tttgatcctg taacacgtca tttgagtgat ggtgtaggaa
    43381 atagtgatga cacagatgaa ttatacagat aaagtaaagc gcgttgctat cattgcaaac
    43441 ggcaaatatc agagtaagcg ccttgcctca aagctttttg gcgtctttaa ggacgatccg
    43501 agtttttacc tatccaaaaa aaatccggat attgtgattt caattggcgg agatggcatg
    43561 cttctatcag cctttcatat gtacgaaaaa gaattagaca gggtgcgatt tgtaggcatt
    43621 cacactggac accttggttt ttacactgat tatcgtgatt ttgaggttga tcaattgata
    43681 gccaatctta gaagagacac cggtgagcaa atttcttacc ctattttaaa ggtagttatt
    43741 acgcttgatg acggtcgcct gtttaaggct agggctctca atgaagcaac tattaagcgt
    43801 atcgagaaaa cgatggttgc agatattatc attaacaatg tcaagtttga aagctttcgt
    43861 ggtgatggca tctctgtatc cacaccaact ggaagcacag cctataacaa atccttaggt
    43921 ggagctgtat tgcacccaac gattgaggcc cttcagctaa cagaaatctc gagcctgaac
    43981 aatcgtgtat ttagaacctt ggggtcctca gtgattattc ctaaaaaaga taaaattgag
    44041 cttgttccaa aaagactagg cgtttatact gtctctgttg acaataaaac ctaccactta
    44101 aaaaatgtgg ttaaggtgga atattttatc ggcaatgaaa agattcattt tgtgtcctca
    44161 cctagccaca ccagcttttg ggaaagggtt aaggacgctt ttattgggga tagtgaatca
    44221 tgaggtttga atttgttgca actaaaaaaa caaaggtaaa gaccctttta aaagagcacg
    44281 atgtgtcaaa gggattgctc gctaagatta aatacaaggg tggcaatata tgggtaaatg
    44341 gcgttgcgca aaatgccatt tatttattgg atattggtga tgtggtggct attgatattc
    44401 caaatgagga gtcctttgag caattgacag cgatttcgca tgaccttgat attgtgtatg
    44461 aggacgaaca ttttctcatt ctcaacaagc ctgctggcta cgctagcatt ccaagtgcta
    44521 tccattctaa tactatagct aattttatca aggcttatta tatcaagcag gactatccca
    44581 ataaacaggt tcatattgtg acgcgcttag atcgggatac cagtggctta atgctctttg
    44641 ccaagcatgg ctatgcccat gccagattag ataagcagct acagcaaaga gctatcaata
    44701 aacgctatta tgctcttgtt tgtggtcagg agaggcttcc agatcaaggt gagattatag
    44761 ctcctattgg ccgtacggac gacagcatta tcacaagaac tgtcacgcca aagggaaagt
    44821 atgctaagac aagctacaag gtcattgccc gctatcctga aaatgtctct ctagtggata
    44881 ttacgctgca cactggtcgg acccatcaaa ttagggtaca ttttgctcat cttggttttc
    44941 cacttttggg agatgatctg tatggtggtc gattggacct tggcatgact agacaggcgc
    45001 tgcattgtca ccatcttagc tttacgcacc catttacaga aagtagaagc gatcatacaa
    45061 tatgcttgac agatgacttt gagagcgtta tcatagattt acagaaaaaa gatagaggtt
    45121 agttaatgag tattcgtaat ttatttggtg gtttaaggga aaaaattgtc ggcaaaaaca
    45181 tgaagattgt tttccctgag ggaaatgatg agcgtgttgt acgtgcagca gcacgtctaa
    45241 agtttgaagg tcttgttgag ccaattattc ttggtcaggc agatgatatt cgcagcctgc
    45301 taacacagct aggctttgct gagcagcact atacaatcat taacccaaat gattatgctg
    45361 attttgagaa aatgaaagca gcctttgtag agcttcgtaa ggtcaaggca acgcttgaag
    45421 atgctgatag actgcttaga gatgtcaatt actttggtgt tatgctggtt aagctaggct
    45481 tagcagatgg catggtttca ggggctattc attcaacagc tgatacggtg cgtccggcgc
    45541 ttcagattat caagacaaag ccaggcattt ctagaacatc aggtgtcttt ttgatgaatc
    45601 gcgaaaatac agagcagcgt ttagtgtttg ctgattgtgc cattaatatt gacccaactg
    45661 ctcaggagct cgcagaaatt gcggtaaaca cagcagatac tgcgaaaatt tttgatattg
    45721 atcctaaggt tgccatgctt agcttttcaa caatgggctc tgctaaagcc ccacaggttg
    45781 aaaaggttca agaggccgtc cgtattgcta aggaattgag gccagagctt gctttagacg
    45841 gtgagcttca atttgacgca gcctttgtac caagtacagc agcgatcaaa gcccctgatt
    45901 catcagtggc aggccatgcg aatgtttttg tcttcccaga tttacagtct ggaaatattg
    45961 gctataagat tgctcagcgc ttaggcatgt ttgatgctat cggaccaatc ctgcaaggat
    46021 tgaacaagcc tgttaatgat ttatcacgtg gctctagtgc agaggatatt tacaagctag
    46081 ctattattac agcagcgcaa gcgcttgaaa atgagtctat caattaactg ctaatagcca
    46141 ttaagttcac aaggcttagc tatagtagat gttgcttaaa acgagttgga taagccagct
    46201 cgttttttca gaaagtgagg aaggaaatga caaagattgc attagtaaca ggcgcctctg
    46261 ctggctttgg taaagccatt gcagagcagt taatagccca aaacatcaag gtgatcggag
    46321 cagcccgccg catagaaaag ctaagagagc tagaaggtat ttttggttct gagaggtttt
    46381 atccgcttca aatggacgtt tcagaaccaa ctgccattga taaagcactt gcagaattac
    46441 ctaaagaatg gcaggccatt gatattttag ttaataatgc aggactagcc ttaggacttg
    46501 ataaggccta tgaggctgat gtcgccaact ggctaaccat gattaatact aatattattg
    46561 ggcttatcta tttaacacgt caggtattac cgcaaatggt aagcagcaac aatggcatga
    46621 tcatcaatat cggctcaact gctggcacta ttccctatcc gggagctaat gtttatgggg
    46681 cttcaaaagc ctttgttaag cagttttcgc ttaatttaag ggcagattta gcaggaacaa
    46741 atatcagggt gaccaatatt gagcctggcc tttgtgaggg aacagagttt tctcatgttc
    46801 gctttaaggg tgaccatgag cgtgttaaag cactttatgc aggtgcacat gctattcagc
    46861 caagggatat cgcaaatact gtctcatgga ttattgatca gccagagcat gttaacatta
    46921 accgcgtgga aatgatgcct gtctcacaaa gctatggttc tcagcctgtt agccgtcatg
    46981 actaagaatt acaagagcag atgtaaaagg attgtcgaag tgcaacccaa aaagacttaa
    47041 agcctagctg ttttatagcc tggctttaag tctttttctc taatttttct tagaaatgat
    47101 ccgaaagaga aggtccagat gtgacatctg accacccaac aatggcctgc cctgtttctt
    47161 ccaaatagtg ctgcagcata ggcttgaagt ccaaaatcat gtcatagacc ccaacaaatt
    47221 gcttggtatc atcgtacaag gcttgatatt gctgcatata aatatgatcc tgtgaagcag
    47281 tcggaataag atacagctta ctgccagttg ccgccttgtg caaatcagtc aagatccaat
    47341 cctcaatgac atcatgctta tcagaagcaa aaaaattgcc attaaagcga tgattatcaa
    47401 agatgatctg cccctgatga tcagcaattc tagcctgaag gggaagatag gttaaaaaat
    47461 gtggggctaa ggcttggtaa aattgcatga ggtatttagc aagtcttaaa gtttgctgac
    47521 tatcagtaaa ggtatgatca ctaacggtaa atccttgctc tttgtctgcc tgattaaaat
    47581 aaagtacagg tagtgaggct tcaaggttct gaaaggtaaa aatggcctga gcctttttga
    47641 gctgctcagt agtcagctga cggacaatag tgatatgaaa cagatcgcta aactcttgtg
    47701 ataaggtggt aaaaaaagtc ttttgcagat tattcttatc atcaaccagt gctaaggtat
    47761 aaatcgtttt agtcataagg ctatcatagc tttattttgt ttaaatagca atgaaacagc
    47821 cttttagtct acagacttag ttgatagctt aataaaagaa agcaatatga aaaaatgatt
    47881 aaagcaaact agttgacttg ttagtttaaa ctttttataa taaatcaaat gagaagataa
    47941 tatgaggctt agcctaagct gctgagctta tctgataatc attcttctta gcactgagat
    48001 aacccccttt atcgattaat tggagaatct atgatacgtt ttaataatgt ttccaaaacc
    48061 tttggtcaca ccaaggtgct gcaggagcaa agttttcaaa tacagaatcg cgaatttttt
    48121 gtgctggtcg gtccaagcgg ctctggcaaa acaaagctct taaaaatgat caattgcctt
    48181 actgaaccaa gctctggcga aattctatta aacggaaggc cacaaaaaga gctagatttg
    48241 cgagatatgc gcttatctat tggctatgtt cttcagcaaa ttgccctgtt tccaaacctt
    48301 acagttgctg aaaatatcgc tattattcca gagatgaaga agtggtcaga caaagagatt
    48361 agaactaaga cagaggaatt gttagataag gttggattgc ctgcaaggga ttatctaaat
    48421 cgctatccca gtgatttatc cggtggagag cagcagagga ttggtattgt tcgtgccatc
    48481 atttctcacc ccaaggtgct gttaatggac gagccgtttt cagccttgga tcctatttca
    48541 cgcaagtaat tacaggactt gatgttaagt cttcacaagg agtttgatat gacaattgtc
    48601 tttgttactc atgatattga tgaggctatc aagcttggag atcgtgtggc tgttttaaat
    48661 gaagggcaaa ttgttcaact ggatcgacca gatgcgatca tagctgcgcc tgctaatgat
    48721 tttgtagcaa gtctatttgg aggtcgtgat tatgcctagt ttactgatga ccttttggga
    48781 tcgttttggt gattgggcaa gggcattagg agagcacttg cagatttctc ttctttcttt
    48841 gctggctgcc ttgctgatag gcattccgct tgcagctctg ttgagtaaaa gtaagcgctg
    48901 gtcaaatatc atcttgcagc tgacaggtgt ttttcaaacc attccttccc tagccttgtt
    48961 gggactattt atccctctaa tgggaatcgg aactgctcca gctgtaacag ctttggttat
    49021 ttatgccata tttcctattt tacaaaatac gattactggc ttaaatgcta ttgatccaag
    49081 tcttgtagag gccggaacag cctttggaat gaccaagtgg gagcgactga aaatatttga
    49141 aattcctatt gctatgccag ttattatgtc aggtgttcgg acctcagcag tgatgattat
    49201 tggaacagcc accctagctt ctttgatcgg agctggcggc ttagggacct ttatcctatt
    49261 aggaattgac cgtaataatg ctcagctgat tgtgattggt gctgtgtcgt cagccttgct
    49321 tgcgatagtg tttaacagtc ttttgtgata ccttgagaag gcctcactga ggcgtattgc
    49381 gataagcttt gctgcgacct tattactgct cttaatttcc tatactccaa tgtttgtcaa
    49441 gcggtttgtt aatcagtcaa atactctggt gattgctggc aagctaggag tagagccgga
    49501 tattttgatc aatatctata aagagctgat tgaagaccag tccaagctta aggttgaatt
    49561 gaaacctaat tttggcaaga caagcttttt atacgaggcg attaaatcag gagatattga
    49621 tatttatcca gaatttacag gaaccatcac ctctagccta ttaaagaaaa agcctaagct
    49681 ttctaatgac cctaatcagg tttacttagc tgctaaggag gggattgctg agcaggatca
    49741 gttgacgctt ttaaagccct ttgcctatca aaatacctat gcagtggcga tgcctgaaaa
    49801 aatagctgac gaatttaaca ttcaaagtat ttcagatgtg aagaaatatg aaaaacagct
    49861 aaaggctggt tttacactag aatttaagga tagagaggac ggctataagg gcatacagga
    49921 taagtatgat ctacatttat cagttgcaac gatggagcca gctcttaggt accaagccat
    49981 tcagtcagga aacattcagc tgacagacgc ttattcaact gatgctgaga tcgtgaaata
    50041 tcagcttcga gtcttaaagg acgataagca gctctttcca ccttatcaag gagcgccatt
    50101 gatgaaggct tccttactaa gaaagcaccc tcatctcaaa acgattctca atcagttatc
    50161 aggaaagatt actgaagagg agatgcaagc aatgaactat gaggtgtccg taaagggcag
    50221 agcagctagc cttgtggcac atgactacct tgtaaaggcc ggtcttattg caagaaccaa
    50281 ataagcaggc atgctagtct tattctggac tggcatgctt tatttatgtg atttttagtc
    50341 tgtctggctc tgcaaggtgt gtgccaaata accgctcgtt tgatgtgtgg ttattgattt
    50401 agtagctaag gattggaatc ttaaaataaa atccgaacgt ttgtctaaaa aaagctttaa
    50461 aaattgacaa aacataaacg aaaggataaa ataaattaag gaaaggtaac attttaccta
    50521 gcgatgcctc ggacaagctt gaggtcatag gaaggtcatt ttatatagaa gcttatgtca
    50581 gctgcagatc agggaagtcc ttgctggatt agtagctgaa tgttgaaaaa ggagagaaat
    50641 gatgtttaat gacatgcctg tatttgatta tgaggatatt caattaattc ctaacaaatg
    50701 tatcatcaat agtcgttcag aagcagatac gagtgtaaga cttggtaatt atacctttaa
    50761 gctacctgtt attcccgcca acatgcaaac cattattgac gaaacaattg cagagcagtt
    50821 ggcaagagat ggttatttct atattatgca ccgctttgat gaggaggggc gcaagccctt
    50881 tatccagcgt atgcatgagc aacagctcat cgcctctatt tcggttggtg taaaggatta
    50941 tgaatacgat ttcgtctctt ctttgaagga ggacgcacct gagtttatca cgattgatat
    51001 tgctcatggc catgctgata gtgtgatcaa aatgattaag catattaagg ctgagctgcc
    51061 tgagaccttt gttatagctg gaaatgtcgg aacaccagag gctgttcgag agctcgaaaa
    51121 tgctggtgct gacgcaacaa aggtcgggat tgggcctggt aaggtttgta tcacaaaggt
    51181 taagacaggc tttggaacag gggggtggca attagctgct gtacgttggt gtgctaaggc
    51241 tgctcgtaag ccgattattg ctgatggcgg tattcgtact catggtgata ttgccaagtc
    51301 gattcgattt ggggcaacaa tggtgatgat cggttcactc tttgcaggtc atattgaaag
    51361 cccaggcaag atggtagaaa tcgacggaca gtccttcaag gaatattatg gctctgcctc
    51421 tgaatatcaa aaaggggagc ataaaaatgt cgaaggcaag aagattttgc ttccaaccaa
    51481 gggtcatcta gctgatactt taaccgaaat gaagcaggat ttacagtcat caatctcata
    51541 tgctggaggc agagatttgg agagcctgcg tcgtgtgaat tatgttatcg tgaaaaattc
    51601 tatttggaat ggtgactcta tttaaagcct tggctaaaga cctagtctaa ataaggataa
    51661 gcaagctgat tgatgctgag aataagcaca gcgtgtctat aggacgcctg aatgtctagt
    51721 agccagtaaa gcttttaggc ttgctgattg gataggtcat tgtgcctatg tgcagcaggg
    51781 ctctagggac ttagataaaa aggagacatg atgaggttac tggaggagcg tatcctagct
    51841 gatggaactg ttttaggtga gacgattttg aaggtggatc aatttttaac acatcaggtt
    51901 gactatcgct tgatgaagga aatcggtaga gtatttgctg atcaatatgc tgatttgggc
    51961 attaccaagg tggtcaccat tgaagcctct ggtatcgcac cagcagttta taccgcagaa
    52021 gctcttgagg ttccgatgat ttttgccaaa aagcacaaaa atatcacgat gacagaggga
    52081 attttaacag cagaggttta ttcctttacc aaacaagtga caagtactgt ttctattgca
    52141 ggaggactgc tatcaaaaga agatagggtt ttgattattg atgacttttt ggctaatggt
    52201 caagcggcaa aaggcttgat tgatatcatt catcaagcag gggccaaagc tgttggcata
    52261 ggcattgtca ttgaaaaatc ttttcaggct ggacggcaat tgcttgagga tttgggagta
    52321 gaggtcactt cattggctcg tattaagcat tttgacaatg gaatagtaag ctttttggag
    52381 gctgatgcct gatgactgct tcttatctct cagcattaag ctttttactt gtatagctat
    52441 accagcttta tttcagtagc tattggctgg tgataaggga tattggtatg gcggtgcatt
    52501 acggcgagcc gtgggcagtt gcccttgcgg ctttacgatt tagtatagac tatcaagaat
    52561 tgactgcttc ctttttatcg agatgaatca ttagacagac aatcatgatt tggcgtgaag
    52621 gctgctttca gtaaacatta catcatcaaa aatcagctag gtattcactt agctgatttt
    52681 tagtgcttat aatgtagccg aaaggctccc tttaacccgt ctgagatagt aacctgacca
    52741 tctttggtaa tgataatgcc ttccacctca ggcagcttat ttagctgact taggacaaag
    52801 gaatgctcta agccaaaaag acgactactc catagctcac catcaagtga gaattggctg
    52861 acaatggtta ggctagccat attggtcttg ataggatagc cgttgtgagg atcaagaagg
    52921 tgatgataag ttttgtcttt gatttgtaat tgtctctcgc cgattcctga ggttactaca
    52981 gatttattgt taaccttaat cacgccgaca tgctgtcctc ttttttgatt ggtctgctgg
    53041 atcccaacgt aaaacaagcc attatgtcgt tgcttgttgg tgccatgcac aaggacattt
    53101 ccacctagat tgataagagc agcagtgata ccgtctttaa taagaaatgc catgagctta
    53161 tcagcaatat agccctttgc tagggcacct aagtcgatag acatgccctt ttctttcaaa
    53221 aaaatacttc caaggctttg atcta
//
LOCUS       DARYXZ010000008        50812 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYXZ010000008 DARYXZ010000000
VERSION     DARYXZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50812
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            110..637
                     /locus_tag="TV186_000386"
     CDS             110..637
                     /locus_tag="TV186_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL1531815.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TV186_000387"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TV186_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL1531816.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TV186_000388"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TV186_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL1531817.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TV186_000389"
     CDS             2207..2839
                     /locus_tag="TV186_000389"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL1531818.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TV186_000390"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TV186_000390"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL1531819.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TV186_000391"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TV186_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL1531820.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TV186_000392"
     CDS             3914..4657
                     /locus_tag="TV186_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1531821.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TV186_000393"
     CDS             4767..5867
                     /locus_tag="TV186_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL1531822.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TV186_000394"
     CDS             6223..6930
                     /locus_tag="TV186_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1531823.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TV186_000395"
     CDS             7071..7787
                     /locus_tag="TV186_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1531824.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TV186_000396"
     CDS             8009..8854
                     /locus_tag="TV186_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1531825.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TV186_000397"
     CDS             9226..10071
                     /locus_tag="TV186_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1531826.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TV186_000398"
     CDS             10149..11519
                     /locus_tag="TV186_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL1531827.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TV186_000399"
     CDS             11512..12576
                     /locus_tag="TV186_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL1531828.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TV186_000400"
     CDS             12577..13269
                     /locus_tag="TV186_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531829.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TV186_000401"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TV186_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1531830.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TV186_000402"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TV186_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL1531831.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TV186_000403"
     CDS             complement(16695..17369)
                     /locus_tag="TV186_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL1531832.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TV186_000404"
     CDS             complement(17379..18755)
                     /locus_tag="TV186_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL1531833.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TV186_000405"
     CDS             complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TV186_000405"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL1531834.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKNHCKRL"
     gene            20126..20683
                     /locus_tag="TV186_000406"
     CDS             20126..20683
                     /locus_tag="TV186_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1531835.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20720..21613
                     /gene="htpX"
                     /locus_tag="TV186_000407"
     CDS             20720..21613
                     /gene="htpX"
                     /locus_tag="TV186_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL1531836.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21901..22434
                     /locus_tag="TV186_000408"
     CDS             21901..22434
                     /locus_tag="TV186_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL1531837.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22619..23305
                     /gene="covR"
                     /locus_tag="TV186_000409"
                     /gene_synonym="csrR"
     CDS             22619..23305
                     /gene="covR"
                     /locus_tag="TV186_000409"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL1531838.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23309..24799
                     /locus_tag="TV186_000410"
     CDS             23309..24799
                     /locus_tag="TV186_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL1531839.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24990..25484
                     /gene="nrdR"
                     /locus_tag="TV186_000411"
     CDS             24990..25484
                     /gene="nrdR"
                     /locus_tag="TV186_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL1531840.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25468..26631
                     /locus_tag="TV186_000412"
     CDS             25468..26631
                     /locus_tag="TV186_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL1531841.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26632..27540
                     /gene="dnaI"
                     /locus_tag="TV186_000413"
     CDS             26632..27540
                     /gene="dnaI"
                     /locus_tag="TV186_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL1531842.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27590..28900
                     /gene="der"
                     /locus_tag="TV186_000414"
     CDS             27590..28900
                     /gene="der"
                     /locus_tag="TV186_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL1531843.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29241..32333
                     /locus_tag="TV186_000415"
     CDS             29241..32333
                     /locus_tag="TV186_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1531844.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32537..33130
                     /locus_tag="TV186_000416"
     CDS             32537..33130
                     /locus_tag="TV186_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531845.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33174..34505
                     /locus_tag="TV186_000417"
     CDS             33174..34505
                     /locus_tag="TV186_000417"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL1531846.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34553..35035
                     /locus_tag="TV186_000418"
     CDS             34553..35035
                     /locus_tag="TV186_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1531847.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35144..36718
                     /gene="mltG"
                     /locus_tag="TV186_000419"
     CDS             35144..36718
                     /gene="mltG"
                     /locus_tag="TV186_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL1531848.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36791..37273
                     /gene="greA"
                     /locus_tag="TV186_000420"
     CDS             36791..37273
                     /gene="greA"
                     /locus_tag="TV186_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL1531849.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TV186_000421"
     CDS             complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TV186_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1531850.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38517..38795)
                     /locus_tag="TV186_000422"
     CDS             complement(38517..38795)
                     /locus_tag="TV186_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL1531851.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
     gene            39088..39825
                     /locus_tag="TV186_000423"
     CDS             39088..39825
                     /locus_tag="TV186_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL1531852.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            39864..40364
                     /locus_tag="TV186_000424"
     CDS             39864..40364
                     /locus_tag="TV186_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1531853.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            40383..41072
                     /locus_tag="TV186_000425"
     CDS             40383..41072
                     /locus_tag="TV186_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL1531854.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            41466..41708
                     /locus_tag="TV186_000426"
     CDS             41466..41708
                     /locus_tag="TV186_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL1531855.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            41888..42682
                     /gene="racE"
                     /locus_tag="TV186_000427"
     CDS             41888..42682
                     /gene="racE"
                     /locus_tag="TV186_000427"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL1531856.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            42679..43668
                     /locus_tag="TV186_000428"
     CDS             42679..43668
                     /locus_tag="TV186_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL1531857.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            43644..44165
                     /locus_tag="TV186_000429"
     CDS             43644..44165
                     /locus_tag="TV186_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL1531858.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            44162..44623
                     /locus_tag="TV186_000430"
     CDS             44162..44623
                     /locus_tag="TV186_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1531859.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            44620..45366
                     /gene="xerD"
                     /locus_tag="TV186_000431"
     CDS             44620..45366
                     /gene="xerD"
                     /locus_tag="TV186_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL1531860.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            45366..46073
                     /locus_tag="TV186_000432"
     CDS             45366..46073
                     /locus_tag="TV186_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL1531861.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            46070..46609
                     /locus_tag="TV186_000433"
     CDS             46070..46609
                     /locus_tag="TV186_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL1531862.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            46846..47568
                     /locus_tag="TV186_000434"
     CDS             46846..47568
                     /locus_tag="TV186_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1531863.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            47565..47843
                     /gene="yidD"
                     /locus_tag="TV186_000435"
     CDS             47565..47843
                     /gene="yidD"
                     /locus_tag="TV186_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL1531864.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            48002..48550
                     /locus_tag="TV186_000436"
     CDS             48002..48550
                     /locus_tag="TV186_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL1531865.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
     gene            48929..49360
                     /locus_tag="TV186_000437"
     CDS             48929..49360
                     /locus_tag="TV186_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531866.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            49575..49988
                     /locus_tag="TV186_000438"
     CDS             49575..49988
                     /locus_tag="TV186_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531867.1"
                     /translation="MTVKKKVIILLGMVAILVMGGIFMFSYNQNQAKMLERQFNHEQK
                     RIVLYLLNHYSGINEIEFNDIENNSTTGSKNVLLTINNKIKMEVTFFNLNDDTDNYVI
                     SWNGKLSLIDKNPITHLSSIDKIKVKYWSNNDSNR"
     gene            49972..50226
                     /locus_tag="TV186_000439"
     CDS             49972..50226
                     /locus_tag="TV186_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531868.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            50242..50643
                     /locus_tag="TV186_000440"
     CDS             50242..50643
                     /locus_tag="TV186_000440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531869.1"
                     /translation="MMKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQE
                     RAAIYFSNTYENIHKIKIIGIDKNLKTGSMNKATIVNSKYYISVTFMGGEIYTGVEQA
                     SKDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            50646..>50812
                     /locus_tag="TV186_000441"
     CDS             50646..>50812
                     /locus_tag="TV186_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531870.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVV"
BASE COUNT        14825 a         9313 c        11914 g        14760 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt tattaggaat accggctttt cgagggtact
    19321 tgtttggcgt ttcctttttc ttttcgacaa gagtgatata gcggccatct ccattaggaa
    19381 gttggtaggg ctggtgatca agcaccttag caaaaagtag ctgaagtgcc tttttagctt
    19441 cttctaattc ttggtccgct gcttgtgcct ttaaagcaat cagttttccc ttgattttta
    19501 aaaaaggaat ggtcaactca gacagaatct gcatgcgggc aacagctcta gcagttacca
    19561 aatcaaattg gccacgaaat tgcttgtctt gtccaaaatc ctctgcccta ccatgataga
    19621 aatgtactcc ctctaatcct agctctttag caaggagctg aagaaaatgt atgcgcttat
    19681 tgagagaatc aataatggta acatcaagct ttggaaacat aattttcata ggaatgcttg
    19741 ggaagcctgc tccagcccca atatctaaca gcctgagagg ctcatttgga atatatccct
    19801 gtaaaagcgg agcaacagag tcataaaagt gcttgagata gacttcattt tcttcagtga
    19861 tggctgttaa gttgatctta cggttccaat caaccaaaag cttaaaataa gtgtcgaatt
    19921 gttctttttg atgatttgtc agagcaaatc ctgcttgctc caggacaagg taaaaggctt
    19981 ggggtgtcat atatatcctc tgtttttaat taattgctac tattttagca taaaatagca
    20041 gaaaactgct gaaaagtccc ttcaatactt gctattaaac tgaaaattgc tataattgag
    20101 acacaaagat taaaggagaa ttacaatgcc aatgttttta gtaatagtag cccttatcgg
    20161 tgtgctggtt gtttggctga tggttagcta taatggcctg gttaaagctc gtatgcatac
    20221 aaaagaagct tggagtcaga ttgacgtgca gctaaagcgt cgcaatgact tgattccaaa
    20281 ccttgttgag acggtcaaag gctatgctaa tcatgaagag aaaaccttag aaaagattac
    20341 tagtcttaga tcacgtgtgg ctgatgctac tacaccgcag gccacaatgg cagcctccaa
    20401 tgaattgagc aagcaggtca ctagcctctt tgcagttgca gagagctatc cagacttaaa
    20461 ggccaatagt aatttcctaa aattgcaaga ggaattaacc aatacagaaa ataaaatttc
    20521 ttattcgcgt caattattta atacaacaac atcgcattat aaccttaagc tagaaagctt
    20581 tccgagcaat cttgtggcta aattgtttgg cttcaagcca agtgagtttt tacaggttcc
    20641 tgaagctgaa aaagaggttc caaaggtaga ctttaccgtc tagtctaatg cggctaatca
    20701 aggtcagaag aggacatcaa tgctttatca acaaatttca caaaataaac gacgaactgt
    20761 tatcctgctt tttgcctttt ttgtcttact ggtagtgatt ggcgctgctg ctgggtattt
    20821 actggctgac agctaccagc tgggggctgc ttttgctctg attattggtg ctatttatgc
    20881 ctttagcatg atttttcagt caaccagcct cgttatggga atgaataagg ctaaggaaat
    20941 cacagtaaac gatgctcctg atttctttca tattgttgag gatatggctc tggttgctca
    21001 gattccaatg ccaagagtat ttatcattga tgatccctca ctaaacgcct ttgccacagg
    21061 ctccagccct caaaatgcag ctgttgcggc aaccactggt ctactaaagg tgatgaatcg
    21121 tgaggagtta gaagcagtga ttgggcatga agtcagccat attcgtaatt atgatattcg
    21181 gatatccact attgcagttg ctttagctag tgctgtcaca ctgatttcca gcattggggg
    21241 gcgtatgatg tggtatagcg gtggcaggag acgtgataac gatcgcaacg ataatggctt
    21301 tggcgctatt atgctgattt tctcaatctt gtcactgatc ttggctcctc ttgcggcctc
    21361 tctggttcaa ttagccattt ctcgtcaaag agagtatctg gcagatgcca gctctgtcgc
    21421 gttaaccaga aatccagagg gcatgattag ggctctacaa aagctaagca attcacagcc
    21481 tatgactcat ccagtagatg atgctagcgc agccttatac atcaatgagc ctagaaaaaa
    21541 agaaaagctt agcgctttat ttagtaccca tccgccgatt gaagatagaa ttgaacgctt
    21601 gaagcatatg tgagagcttg agactagctc agctctcatt tttactagcc ataatgttca
    21661 gaaaacatca ttaattaatt gttttgaccc ggacattttt taagactttt atggaaattt
    21721 gggctatttt cataggggtt ttatggttaa acatttgatt gttggcttgt caatacttat
    21781 ttgtatccag acttaatgtt aaaaaaagtt atgaatttgt cataaagcta ttgacaaatt
    21841 cttgatatca tagtaaaaat agattagagt tttattagga agtgttttat aggagaaagc
    21901 atgttatctg tttcagatat tagaaagcga ccggaaggca ttcgctttga gagagagtac
    21961 gatgttaagg aagcgctgct tatacgtgat ccgcaggtta tagatattaa taacgtcaga
    22021 gcttcgggga gagctcagtt tgatgacggc ttgtatctat tagagtatca gctgggctat
    22081 cagattaccc tgccctcgag ccgttccatg gcgcctgttg tcttagatga gatgcagacg
    22141 gttcaggagc tgtttatcga ggaagcagat gtggcaagta agcaggaaat ggttgatgaa
    22201 aaccttgtct tagtcttatc agaggatcag cttgaccttg aagagagtat tattgacaat
    22261 attttgttgg cgattccctt gcaggtattg acagaggctg aaaaggagtc acaaatcttg
    22321 ccgacagggg aggattgggc agtcttaact gaggagcaat accaggccca gcagaaggaa
    22381 aaagcaaaag acaacagtcc ttttgcgggc ttacagggtc tttttgatga gtaaaaataa
    22441 aaattaaaga tgtctgtatt ttttatttga aaaaagaaca gttgtctggt atactttata
    22501 aatatacggc atattagtca ttttgatgac taaatagcaa tacttgatta atacaaaatg
    22561 gatgaatctt gtacatagct gataaggggc tgtgatacag gaagtaagga ttggtgtaat
    22621 gacaaagaaa attttaatta tcgaagatga aaagaatctt gcaagatttg tttcgcttga
    22681 gctacagcat gagggttacg aggtaaccgt cgaggttaat ggtcgtgagg gcttggagac
    22741 agccctagag aaggactttg acttaatcct tcttgatttg atgcttcctg agatggacgg
    22801 atttgaagtg acacgtcgat tgcaaacaga aaaaacgact tacatcatga tgatgactgc
    22861 gcgtgactct attatggacg ttgtagctgg cttggatcgt ggtgctgacg attacatcgt
    22921 gaagccattt gccattgagg aattgctggc gcgtattcgt gctatcttcc gtcgtcagga
    22981 cattgagtca gagaaaaaga ctcctagtca aggcgtttac cgcgacttag tcttaaaccc
    23041 tcaaaaccgc tctgtcaatc gcggtgatga cgagatttca ctgactaagc gtgaatatga
    23101 cctgcttaat attttgatga caaacatgaa tcgtgtcatg actcgtgagg agctcttgtc
    23161 taacgtttgg aaatatgacg aggctgttga aactaacgtt gttgatgttt atattcgtta
    23221 ccttcgtggg aagatcgata tccctgggaa agagtcttac attcaaactg ttcgtggaat
    23281 gggttatgtg attcgcgaga aataattgat ggcaaagcag aaaaaatata agaaaacgtt
    23341 accaaaacgt ttatcgaatc ttttgttcgt tctcttcttt tgcattttct ctgcctttac
    23401 cctactcgct tatatttcaa caaactactt tttgttgaaa cgagaaaagc aaactatttt
    23461 tcaggctgtt aacattgtta gagttcgtct ctctgaggtg gactctaatt ttacgttaga
    23521 gaatttagca gaggttctct ataaaaatga cagaacgcat ttaaagattg atgacgcaaa
    23581 tggtagtcgt attatcagaa gtgaacgaaa tatcaccaac acgctcaatg ccaatgagga
    23641 tatctatgtc tacaatgttg ataagcaaat gatcttcaca acagatgacg aagaggcctc
    23701 gccaggctta aatggaacta ttggtaaggt aaccaaggac cacattgagg agcaatacaa
    23761 gggcttttca atgactcaga aggtctactc taataagaca gggaagtttg taggctatgt
    23821 tcaggttttc catgacttgg aaaactacta catgatcaga gcacgcctct tcttttggct
    23881 tttggtggtt gagctctttg gggttggtct ggcgtatttc attatcttaa ttgtcacacg
    23941 caacttcttg aagcctctga acaatcttca tgatgtgatg cggacaattt ccaaaaatcc
    24001 agataatctg atgctgcgct cgggtatttc ctcgggtgat gaaattgagg aattgtccgt
    24061 tatttttgat aaaatgcttg ataagattga gacgcataca cgattgcaat caagatttat
    24121 tagtgacgtc agtcatgagc tgcgcacgcc agttgccatt atcaaggggc atattggatt
    24181 attgcagcgc tggggcaagg acgatagtgc tattttagat gaaagcctca ctgcagctgc
    24241 gcaagaggtt gaccgaatgg ctattatgat caatgacatg cttgatatga tccgagtaca
    24301 ggggtccttt gaagggcatc aaaatgatac aactgtttta gagagctcta ttgagaccgt
    24361 tgttggtaat tttagggtcc tgcgtgagga ttttgatttt acctggtact ctgaaaatca
    24421 aagaacccta gccaagattt ataaaaatca ttttgagcag gctctgatga ttttgataga
    24481 taatgcggtc aagtattcta ggaaggaaaa gaaaatcgtc atagaattag cggttaatgc
    24541 tagcaatgaa gctgtggtta aggtcaaaga cagaggtgag gggatctcag aagaggatat
    24601 taagcatatt tttgagcgct tctaccgcac cgataggtcc agaaatcgaa ccagcaccca
    24661 agcaggtctt gggattggct tatccatttt aaagcaaatt gttgatggct atcatttaca
    24721 tatggaggtt gagagtgagc taaataaagg gtcggtcttt attttgcgga ttcccttagc
    24781 tgatcatcaa ggctcatagc tgtatacctg cctgagtatc tagtagatgc tcaggctttt
    24841 gactgttcta atgtgtggtg tgatgatgag gtgtttatca gggaaggagg gctcttggag
    24901 gtaaacctga gtgcttgtct attcttttgt tatccctaaa attatggtaa aatagggtat
    24961 tagattaacg atagaattgg ggtgtttgcg tgcgttgtcc gaaatgtaac tataataagt
    25021 caagtgttgt tgatagtaga caggcagaag atggcaatac gattcgtcgc cgcagagaat
    25081 gcgaaagctg tcacacgcgc tttacaacct ttgagcgctt agaagagctt ccattactag
    25141 tgatcaaaaa ggacgggact agggagcagt tttcaagaga taaaatctta aatggtgttg
    25201 ttcaaagtgc ccaaaagcgt ccggtgtcaa gtactgacat tgaaaatctc atttctcgca
    25261 ttgagcagaa ggttcgtaca gcctatgaaa atgaggtgtc aagtactgtt attggcaatc
    25321 tggtgatgga ggaattagca gagcttgatg agattaccta tgttcgtttt gctagtgtct
    25381 ataaaagctt taaggattta gacgaaatcg aagagctctt acagcagatt actaatcgcg
    25441 ttagaggaaa aaagaagagc agtgtagatg atgaagccta ttgatacctt ttcttatatt
    25501 aagcataatc aggttcaata cgattcaagc agcctgattc agttgtattt tcctattatt
    25561 ggaaatgacg cagtggcagt ttatcagtat ttggttcact tttttgatga tggctcagga
    25621 gcccacaaat ttagtgatat tttaaaccat ctgcagtttg gaatgaagcg cctagaggaa
    25681 gccttggtga tgctgacagc tattgatttg ctggtcttat atcagctgcc agatgcttat
    25741 ttgataaaac tacatcagcc cttgggcagg gaagcctttt taaataaccc aatttatcgt
    25801 aggcttttag agcaaaagat tggagatgta gcggttttgg agttgcaaat ggtgattccg
    25861 aaccaggcta gaaacatctc aaagaccttt tcagatgttt ttggaataga ctctcaggag
    25921 cttaagcagc ctcagccatc aaagataaat tttgatttag atagctttca gcagctaatg
    25981 cggcgtgacg gtcttaggtt tgaggatcat caaaaggacg ttatcagtct ttacagtatt
    26041 tctgagcaat accacctaac ctggtttgac acctatcagc tggctaaggc aacagcagtc
    26101 ggcggcagca ttcgcccaga gcgcatgcta gtcaagaagc agcaagaggg cgctcaaaaa
    26161 acaagtgaat cgttctcacc agctgagcag gttgttctta gagagtctaa gcaggacacg
    26221 cctcttgtct ttttagagaa gatcaaaaaa gctaggcgag ctagagtcac aaaggacgaa
    26281 aaggaattgt tgctgactct agcccgcatg aatttcttgg acgaggtcat caatattatg
    26341 gtattatata ccttcaataa gaccaagtca gctaatcttc acaagactta tctgatgaaa
    26401 atggcaaatg attttgctta ccagcgggtt ttaacagcgg aaactgctat tatcaagaca
    26461 cgcgcctttg gtgagcgtaa gcagcaggca aagtcacagc agtccaatgt gcctaagtgg
    26521 agcaatccgg attatcaaga aaaaacaagt caggaagaac aggcaaagct agagcagttt
    26581 aagcaggctg ccttaaaaag gctggagaac ctaggaaaga gtggtgacta gatggaaaag
    26641 atcgggaaaa tggtagagca tttgggacag gctagtcgtg tagctagtgc tgagctgatt
    26701 gaggctatac ttgctgatca ggaggtggct gagtttatca aggctcacca gctatctcag
    26761 gcagaaataa agctgagttt atcaaagttc aaccagtttt tagttgagcg ccggaaatac
    26821 cagacaggtg atgagaccta tattgctaag ggctatcagc ccattttggt catgaacgag
    26881 ggctatgcag atgtgtctta cctagagaca agagagcttg ttgaagccca aaggcaggca
    26941 gctattgcag atcggattca tttggttagt ctgccaagat cttatcgtag ggtttctttg
    27001 tcagctgttg atgttaacaa tgccagtcgt atgcaggtgt tttcagagct tttggatttt
    27061 gttgagcagt atccagcggc agagcaaaag ggtctctacc tttatggcga tatgggggtc
    27121 gggaaatcct atctgatggc tgctatggca catgaattgt ctgaaaaaaa gggtgtatca
    27181 acaactcttc ttcattttcc tagctttacg attgatgtta aaaatgccat ttcaaatggc
    27241 tctgtcaaag aagagattga tgccatcaag catgtccctg ttttaatttt agatgatatt
    27301 ggtgcagagc aggcgacctc atgggtgcgt gatgaggtgc tacaggttat tttgcagcat
    27361 cgtatgctag aggatttgcc aacctttttc acctctaatt acagctttgc agatttggag
    27421 agaaaatggg caaagatcaa aggaaatgat gagacctggc aggccaagcg tgttatggag
    27481 cgtgtgcgtt atttagcacg tgaatgccat ttagaagggg ttaatcgccg ccagggctag
    27541 ctaaacgcta gctcaagcga tggataatga gataaagaaa aggagaatca tggttttacc
    27601 tacagttgcc attgttggac gtcctaatgt tggaaagtcc acgttattta accgaattgc
    27661 aggagagcgt atttctatag ttgaagacgt cgaaggggtt actcgcgacc gcatttacac
    27721 gactggtgag tggcttaacc gccaattttc attgattgac acaggtggta ttgatgacgt
    27781 tgatgctccc tttatggagc aaatcaagca tcaggctcat attgcgatgg acgaggcaga
    27841 tgttattgtc tttgtggttt ctggtaaaga gggcgttact gatgcagacg aatatgtctc
    27901 taagctcttg tatcgtacca acaagccagt gattttggtt gtcaacaagg tggacaatcc
    27961 agagatgcga aacgatattt atgattttta ttctcttggc ttaggagatt ccttcccggt
    28021 atcatcagtt catggtattg gtacgggtga tgttttagat gctatcattg ataacctgcc
    28081 gatagaagag ccagtagaaa acgacgatgt gattcgcttt agcctaattg gacgtccaaa
    28141 tgttggaaaa tcaagcctca ttaatgcgat cctaggagaa gagcgtgtca ttgccagtcc
    28201 tgttgctggt acgactcgtg atgcgattga tacaagcttt accgatgaat ccggtcaagc
    28261 ctataccatg attgataccg caggaatgcg taagtccggc aaggtctatg aaaatactga
    28321 aaaatactca gtgatgcgtg ccatgcgtgc cattgaccga tcagatattg tgttaatggt
    28381 tattaatgcc gaggagggca ttcgtgacta tgataagcgg attgcaggct ttgcgcatga
    28441 ggcaggtaag ggcatgatta tcgttgttaa taagtgggac accatcgaaa aggataatca
    28501 tacagtagct aggtgggagg ctgatattcg tgatcaattt caatttttga cctacgcccc
    28561 tattatcttt gtttctgccg ttacaaagca gcgcttaaac aggcttcctg agttgattaa
    28621 gcgtatcagt gatagtcaaa gccagcggat ctcgtcagct attttaaacg atgtgattat
    28681 ggatgctatt gcgatcaacc caaccccaac ggataaggga cggcgtctaa agattttcta
    28741 tgctacacag gtttctgtga agccgccaac ctttgttgtt tttgtgaatg aagaagagct
    28801 gatgcacttc tcttatctgc gctttctaga aaaccagatt cgtgctgctt tcacctttga
    28861 agggacacca atcaagctga ttgcgcgcaa tcgcaaataa gcccttttat tactcttgtt
    28921 agtattggaa gcagcgagtg ctgttgatgt gcggtgtcta gaccttgtgt gtcaggactt
    28981 ttgaccgacc aataagcctt accagaaatg agaggctgct atccaaatag agcttaccag
    29041 caagcaaggc gtgccaagca ttgatgtcac atgataatca ttagccctag gctagtgatt
    29101 ttttagtgct ttaaagccta tcagaacagc tatatacagc tactcaaata tgttttaata
    29161 gcctttaaga gagatttttg caggaaatct aagctgaagt ttgttataat caaaggataa
    29221 gcaaaaaggt gggagcagat atggctagat taattccggg gcggattcgc aatcaaggca
    29281 tcgagcttta tgagcaaggc ttggtgaaaa tcatagatga caggactgac cttcttcgag
    29341 cagaggtgga tacttatcag gttcaatatg gtatcaatga tgaggatatt aggtgtcagt
    29401 gtgattattt tgagcgaaag cagtattgcc agcacattgc ggctctagaa tattttctga
    29461 aaaataatca gaagggcaag tcgctctcag agcagcttaa caaccagctg gaaagtaagg
    29521 aggaaactaa aaagctgacc tcctttggta gtcttttttt ggacagtttg cacatgaacg
    29581 aggacgacac gaccaaatat aggcttttag cttctggtgc taaaagtcct ttctcatctg
    29641 attactggtg gagccttaag ataaatcgct tgcccggaga gaaggcttat gttatccgcg
    29701 atatcaaggc ctttattcat ttggtcaaag ttgagggctt ttaccagatt ggaaagaatt
    29761 actttgagtc tctttccata ttgcagtttg atcaggctag tcaggagctg attcgttttc
    29821 tttggcgttt atcaacgcat tcagataagt tagattacga atggctattt cctaaccacg
    29881 ctcgtcatct tcggttaccg gcaggctttt ttgaggaggg cattgacctg ctgacggggc
    29941 tttacgagtt ttcatttgag acctcctctc aaacctattc tcatctttat gttcgacctc
    30001 tggaggcaga ggctggtctc tttcagttta cagttgatgt tcatcgcagc tctattgagc
    30061 tttacattaa ggaaaaaaat atagagtatt ttttcaataa tgaatacctg ctatacatga
    30121 acacctttta ccacctgagc ctgaagcagc aaaaaatggt tcaagctatt cgcagcctgc
    30181 ctattgaggc cgatttggcc aagcacattc attttgatct tgatgatcag gctaagctgg
    30241 cagctagctt gctggaattt cgagagcttg gtcaggtgaa ggctcctaaa agctttgata
    30301 ttagagattt ccaagtgact tttgtctttg atattactga aaaaggtgag ttgacctctc
    30361 agctgatttt tgactatggg agcattcaga tcagtgataa ggcaagctta gaccagctcc
    30421 cctttgctag ccattataaa aaagaaagca gtatttatcg tgccttgaag cgctttgggc
    30481 tttctccgca gttttttgct aagaaagcct tgactgaccc caaggactgg tatcgctttt
    30541 ttacagaagc tgttccttat tttgaaagtc taggtagggt tcagctttcc tctaagctcc
    30601 aagatcagcg cttaatggaa agccctcagc ttacagtcaa acgtgaggga ggtcttttag
    30661 atatttcctt tgatttttca acggtttgtc agactgatat tgaaaaggct ttggccactt
    30721 tgtttagtga tcgctcttat tttgtcaatc agtcaggcaa gctggtcgtt tttgatgaag
    30781 agacacaaaa aatcagccgt agcttacagg aactaagagc taagcagctg gcaaatggtc
    30841 acctccagct agaaggaata gctgccaccc agctgtctca tctattttcg gatctgtctt
    30901 ctgttcattt ttctgaggag ctagagaccc taatcaagga cctgcagcac ccggatcgct
    30961 ttgagctggg agagctggcc gttaaggcca aggtgagaga ttatcagctg cagggcatca
    31021 aatggctctc tgtgcttgat aagtatggct ttggtggtat cttggcagat gatatgggct
    31081 tgggcaagac actgcaaatc attgcctttt tatcaagcag gctaaccgag acctccaagg
    31141 tgcttatctt ggcaccctct agcttgattt acaattggtt agatgagttt agtaaatttg
    31201 cccctcagat agatgctgct gtatcctacg ggctaaagcc ggcacgagat gctcttattc
    31261 aagaaggaca tcaggtgacg attaccagct attcttcctt taggcaagat ttagaaacct
    31321 atcaggcaaa tgattatgat tatttaatct tagatgaggc gcagatgatt aaaaatgccc
    31381 agaccaagat tgctcagagc ctgcgtgcct ttgacgtgaa gaattgcttt gctttatctg
    31441 gtacgccgat tgaaaataag ctgcttgaaa tctggtccat ttttcaaatt gttctgccag
    31501 gcctgctgcc atctaaaaaa gcctttttga aaatggaggc cagagacgtt tctcgctata
    31561 ttaagccctt tgtcatgcga cgcaaaaaag aggaggtctt gccagagcta ccagaattaa
    31621 tcgagatgaa ttattacaat gagatgtccg atggtcaaaa agcgatttat ctggcacagc
    31681 taaggcagat gcaggagcgg ctgtctgctg caactgatga tgatattaat cgcagtaagc
    31741 tggaaatcct gtctggtatc acacgtctaa ggcaaatctg tgatactcct agcctgttta
    31801 tggattatca aggaggaagc ggtaagctag acaatctaag aaccttgctg ctgcaaatta
    31861 aagaaaacgg tcatagggct ttgctgtttt cacaatttaa gggcatgctg gctcttgtca
    31921 agcaggaaat ggatcagctt ggcttatcat cttataccat aacaggctca acaccggcca
    31981 atgaccgtca agaaatgaca cgtgccttca ataatggctc aaaggacgcc tttttgattt
    32041 ccttaaaggc cggtggtgtt ggactcaatt taacaggtgc tgatactgtt attttgattg
    32101 atctatggtg gaacccagct gtagaaatgc aggccattag tcgtgctcat cgtattggtc
    32161 aggaggacaa tgtagaggtt taccggttga ttacccgcgg aacaattgag gaaaaaatac
    32221 tggagcttca ggaaaataag cgtcatctga ttaccactgt tttagatggc aaacaaggcc
    32281 tagcaagcat gtctgtcgag gagatcaaag aaatccttgg tcttcagccc tagcatgtat
    32341 ggcttttagc acacgctctt aagcctatca gctaaaggct agtgtctgtt ctctataaca
    32401 aataaggcaa gagaatagag gtgatgagct agtcacatca tttttgcttt gctgcctttc
    32461 tttttaggaa ttactttgaa aaataggatt atttagttta taatagggaa tgctatagga
    32521 aggagagtga gatagaatga caaagcatgc gtttcctctg gttgcagatg gtgagcctat
    32581 tattgagtca gctaggcaga tggctttata tgaaaacgaa gatttgatca caaatattgc
    32641 tggcagctat caagataaac attacgacga catcataaga gaccatcaat ttgctgagaa
    32701 gactcctgtc gtctctaaag gatcccttca tcattctcca gttgtcgatg aagatcatag
    32761 ctacgctcaa aaggccagaa ggcaagcaaa gcaggatgtc aaagaaaaaa gacaggctta
    32821 tattgctaaa aatatggctt atagcccaaa gcaggcaagc aagaaaggtc aaagtggggc
    32881 cttctcttct aaaaaaccag cgacagaatt gagccgtttt acagagaaat taaaccaaga
    32941 gtcttatatt ttagctgagc ttcctcgtca atataaggag ccgcaaaata ccagccaagc
    33001 agctgtcaaa aaaaataatt atgacttttt gaagcgcagc caaatctaca atcatcaaga
    33061 agacagagat catcgtgaaa agaccattgc tcaagagcta aacctgagtc gctttgaaga
    33121 tattaagtaa gctttataca gccttatgtc tgtcaacatt aaaaggagtt aacatgtcaa
    33181 aaacctatca ttttatcgga attaaaggat ctggaatgag tgccttagcc ctgctgctcc
    33241 atcaaatggg gcataaggtt caaggcagtg atgtggagaa gtattatttc acacaaagag
    33301 gcctagagca agcaggcatt accattttgc cctttagcga agataatatt tctccggata
    33361 tggagctgat agcaggtaat gcttttcgtg aggacaacaa tagcgaggtt gcttatgcga
    33421 tgcgtcatca gctgcccttt aaacgctacc atgagttttt aggtgagttt atgaagcagt
    33481 ttactagtct tggtgtagcc ggtgctcatg ggaaaacctc taccacaggc ttgttgtcac
    33541 atgtgctcaa gcacatgacg gctacttctt atttgattgg tgatggtact gggcatgggg
    33601 ctgccgatgc tcgttatttt gtgtttgaat cagatgagta cgagcgtcac tttatgcctt
    33661 atcacccgga atattctatt atcactaata ttgattttga tcaccctgat tattttacag
    33721 gccttgatga tgtgttcaat gcctttaatg actatgctaa gcaggtgaaa aaggctcttt
    33781 ttgtttacgg tgaagatgag gaattaagaa agattagctc tcctgcaccg atttactatt
    33841 atggctttga ggacactgat gatttcgtag cctttgatat cacacgcacg acaaatggct
    33901 cagactttaa ggtaaagcac aagggtcatg ctattggtca gtttcatgtt ccagcctatg
    33961 ggcgtcacaa tattttaaat gctactgcgg tgattgctaa tttatttatt gcaggctttg
    34021 atatgaagct tgttgcagag catctgaaga gcttttcagg ggtgaagcgt cgttttactg
    34081 aaaaggtgat caatgacact attattattg atgactttgc tcatcaccca acagaaatca
    34141 ttgcaacgct tgatgctgct aggcaaaaat accctaataa ggaaatcatc gctatttttc
    34201 agccacacac ctttacaagg accattgctt tgctagatga ctttgcccat gccctaaatg
    34261 aggctgacag tgtttatcta gcgcctatct acggctcagc gcgtgaggtt gataagggtg
    34321 atgtcaaggt ggaggatcta gcggctaggg ttgagcgccc agccaaggtc atctcagttg
    34381 acaatgtatc gccgctgctg gatcatgata atgcagtcta tgtttttatg ggagcaggtg
    34441 atattcagtt gtatgaacgc tcgtttgaag agctgctggc taacttaact aaaaataatc
    34501 aatgattaag cgacctgcct taggcaggtt ttctcgtcgt aaaggaggac ctatgctaat
    34561 tagacatgtg aatcagactg actgggagat tattgctgat atcgaacagg ccaatttttc
    34621 tccccaagag gctgtagcag ccaatgtgat aaaagagcgt gcagagctta tttcggatac
    34681 ctttcttgtg gctgttatcg ccaatcagtt tgtcggctat atcgaaggac ctgtcattgc
    34741 tgagccaagg cttgaggatc acctatttca tggtgtgacc aagaatccag caagaggtgg
    34801 ctatatagcc attaccagtc tttctgttgc tcctggatac caaaagcagg ggattggcac
    34861 agctctctta gctgcaatga aggatttagc agttgcacag gatcggctgg gtatcatact
    34921 tacctgtcat gactatttga ttccttacta tgagatgaat ggttttcaag atcaaggcct
    34981 gtcagcttca aagcatggtg gctctgtttg gtatcaaatg ctatggcagc cataggaagg
    35041 ctattaaagc ttagcatgta ttaagaatta gtaacaaaag ggggatttta ttgcatttat
    35101 agtgcaatta ggatataatg gcggttgatt aagtttagga ggaatggctt tgactgattt
    35161 taaagatgat gagcaaagac gtcagcagca aaaaagcttc aaagaaaaga ttctagccga
    35221 attagaaaaa gcaaatcaga ttagaaaaga aaaagaagaa gagcttttta aaaaggatct
    35281 agaggttcaa gaggctgcta gaagaacagc tcagctttat gcagaatata aaagacaaga
    35341 agcactaagc aataacccca aacaagcgtc tgatatagca gctgcgtcgc aagagacgac
    35401 ctcaacggct tcaacagccc acacctctgc gattaagcta gaagagacag cagtagctac
    35461 tggggatcaa gcattgtcgc caccagagga gcctgcattg agtgaaagcc tgcttaagga
    35521 agaggcaagt gtcgaaggtc agactaagaa gggtggtcca gtgagaagaa aaacaagtaa
    35581 gcgccagcag acagatcgaa tggccaaaaa aatttcgaca gtactgatat cgtcgattgt
    35641 cgctattatt gtggtgattg gcctcgcagg gacagcctat gtgtatagtg cccttaaccc
    35701 tgttgacaaa aatagcgatg actttgttca ggttgaaatc ccagccggct caggcaataa
    35761 gcttattggg cagatccttg aaaaagaggg gctgatcaaa aatagtaccg tctttagctt
    35821 ttacactaag tttaaaaatt tcactaattt tcaaagtggc tactacaacc tacaaaagag
    35881 catgagccta gaagacattg cccaggcctt acaagagggt ggcacagcag agcctacaaa
    35941 gccagtacta ggaaaaattt taattccaga gggctatacc attaagcaaa ttgctaaggc
    36001 catagaaact aatagtaggg caaagaatcg tagcaaggct aaaacaccat ttcactcaaa
    36061 ggatttcttg aatttggtga caagtgatgc ctttattcaa gagatggcta aaaaatatcc
    36121 gaaattgcta ggagatcttc caagcaagga agtagctact tatcagctag aaggctacct
    36181 tttccctgcg acctataatt attataagga aacaacacta aaagaccttg cagaggaaat
    36241 gattgcagcg gcaaatgcaa acctagcgcc ttattatgag gcgattgcag ctagtggcaa
    36301 gacagttaat gaggtgctga ctttggcctc cttagttgaa aaggaaggct ctactgatga
    36361 cgatcggcgt caaattgcca gcgtatttta caatcgctta aataatggca tggccttaca
    36421 gtctaacatt gctatattgt atgcaatggg taaattggga gaaaagacaa ccttagcaga
    36481 ggacgctgct attgacacaa ccattaattc tccttataat gtttatatca atactggctt
    36541 aatgcctggt ccagttgata gtccagggct tgcagctatt gaggcgacta tcaatccagc
    36601 ggcaacagat tacgtttatt ttgtagccga tgtgcgtact ggtgaggttt attatgcaaa
    36661 aacatttgaa gagcactctg caaatgttga aaaatatgtt aacagtcaaa ttcagtaagg
    36721 acaaacatgg tgctttagca tcatgtttgt gtttctgatt cgtcaaaaga aaaaggaaaa
    36781 gagaaagata atggcagaaa agacttatcc aatgacagca gcagaaaaag aacagcttga
    36841 aaaggaatta gaagagctaa aattagttcg tcgtccagag gttgttgagc gcataaaaat
    36901 cgctcgttcg tatggagacc tttctgaaaa ctctgaatac gatgctgcta aagatgagca
    36961 ggcttttgtt gagggacaaa tctcaacctt ggagacaaag attcgctatg ctgagattat
    37021 tgatagcgat gctgttgcca aggacgaggt ggcgattggt aagacagttg ttgtccagga
    37081 ggttggcaca caaacaacag acacttatca tattgtcggt gcggcaggag cagatatttt
    37141 ttctggaaag atttcaaacg agagtccaat tgcacaggcc ttgattggta agaaaacagg
    37201 agataaggtt aagattgagt ctccagcagc tacctatgag gttactatca tcagcgttga
    37261 caaaacacaa taagacttat ctgactatca gtgcagtgtc ctgatagtct ttttagtggc
    37321 ttgcttttta atatcagttg ttgtggtcta ttaaaaagag ctgcacttta gaaagtttta
    37381 actaagatac tttatgacct agtctcatac attaaaaaag cgaacaggtc taattttcgg
    37441 aatccctgaa aattagacct gttcgtttgt tttatcttga gtcagacttt tgtcacagac
    37501 tcttttagct atcttagcga cgcttttttt gtttaccggc gtttcggttt aacttagtcc
    37561 tcttgcttgt gctaagggct tgcttttcag ctgtaacgtc cttgcgtggc tggtgagatt
    37621 tataggcctt aggagggttc tttgcgaact cctctgcaat ttgcttgcgg agccttggtt
    37681 ttaaaaggta ggttgtgatc aattgctgaa tgatactaaa gaaaccacca actagccaat
    37741 acaagcctaa tccggcaggc aggtaaaacg acatgacaat catcataatt ggcatggtgt
    37801 acagcatggc tttcatttgt tcacgttgct cctcagggac tgccatcatt gacagccagg
    37861 attgaacgaa gtataaagcc gcaattacag ctgtaagcaa gacgctgcga tgccccaggt
    37921 caatgcccat aaaggtactt gttgagactc ccttggtaaa ttggaccgca acatacatgg
    37981 cagaaaagaa aggcatttga atcagcagtg gcaaacagcc tataccgcct agcgggttga
    38041 ctccattttc acgctgggcc gccattaatt ctgtttgggc tgccattttt tcttcagtgc
    38101 ttgtagcgtt tttgatgcgt tgattaattg gctcaaaaaa aggctttagg taggccattt
    38161 tttctgattg gtagcttgcc ttccatgatt ggtagagccc aagtggtagg ataatcgttc
    38221 taacaataat agttacaaca atgatggcaa gaccatagcc tagggcggtg ctgttagcaa
    38281 agtaatcaat gagaaaggaa acgggctttc caaggtaatc ccaaatgatg ccctccgggt
    38341 gccccttggc gtctctgccg acacaccctg tcaatgtcag taggaccgat aaggcaagtc
    38401 ctgagaaaag tatgcgattc gttttgagtt tcaatgtgtt tgtcctttaa tttttaatat
    38461 acctaaccat tttactgttt ttttgagaaa ttaacaatag ttctacagta ggatttttaa
    38521 ttgctgatcc taaaatcatg gaaatcctca aagtgagatg gattaacatc aacataggtc
    38581 acctttgccc atttagaagg tccttttctg atttcctgga taaagcgcgt catctttgca
    38641 gggtcactag cctgtgctaa aatctcaaca gtcccatcac tattgttcca cacgcggccg
    38701 taaatatcac caatttccaa agctagtgcg taggttgaat agcgaaagcc aacaccctgc
    38761 accctgcctg aaacgattag tctgaccttt ttcataagtc acctcttttc tttttattat
    38821 agcatagata gcttataaat actaaaagtt gtcatggagc aggcagccaa aggataggca
    38881 aagactgcaa gtgggctatc tgctgaggta aacaataggt cttagtgcag caaggctatg
    38941 tttatggtta gctctccttc ttgtcttcta aaaaggaaag ctaatgggct tacgacacct
    39001 gataagggga gaaagctcct tttaggctga tagccttctg atggttttta tgcaaaagag
    39061 tgaacaattt tgtgatataa taagaccatg attatcacat caaaagcaaa ccatttgatt
    39121 aagcaggcta agaaattact gcaaaaaaag catcgcaagc actcttactt gattgagggc
    39181 tggcacctat ttgaggaggc tcagagatct gggcaggaat tgatacatat ttttgttctg
    39241 gaggaaatgg cagagcgctt atcaggcttt gatcaggttg tcatcgtcag tccagagatt
    39301 ctaaaggagc tgacgagctc tcccaatcca cagggcatta ttgctgaggt taagctttgt
    39361 caacaggcct taccgactag ctatgctgga aaatatttga ttttagagga cattcaggat
    39421 ccaggcaatc tagggacaat cattagaaca gcggacgcag caaagtttga tggggtgttt
    39481 ttgtctgaga agtctgcgga tgtctacaat caaaaaactc tacgctccat gcagggcagt
    39541 cattttcacc tgccgatttg gcgaacggat atttatcagg tcagtcaggt gatgcagcag
    39601 caaaaaatac cagtgctagc aacgaccttg tctcaggatt cgattgatta caaggacctc
    39661 tcagctagga gcagccttgc ccttgtttta ggaaatgaag gtcagggcat tagtcctgag
    39721 atggcagctt tggctgatca gctgattcat attagcatgc ctggacaagc tgaaagctta
    39781 aatgttgcag ttgcagcagg aatcctcatt ttcagcctaa tttaagctag tatggtataa
    39841 taatgatgtg aggtgattag tgtatgcatt atacagaaga tacagaatac atggagcatg
    39901 ttggtcattt gattgctcac cctcgctttc aaaggcttgg agatattgtt cagcatcacc
    39961 attctactcg cttagagcac tctgtcaatg tttcttattc tagctatagg ctggcaaaga
    40021 ggcttggctt agacgccaag agtaccgcac gaggtggctt gctacacgat ttcttttatt
    40081 atgattggcg agtaaccaag tttaacaagg gacacgcttg ggtgcaccct agaattgctg
    40141 ttcgaaatgc taaaaaatta acagcactca acaaaaaaga agaggatatt atcctaaagc
    40201 atatgtgggg agctactatt gcttttcctc gctataagga aagctatatt gttacctttg
    40261 ttgataaata ttgggcggtc aaggaggcca tgacgccgct gcgtcaaaaa tggacgaacc
    40321 gtcgcttcct gcgtcgaaag acgcttcaaa gtcacaatca ttaagtaaaa aaaggagtta
    40381 tgatgaacga taatgttatt tacacacagt ctgacgcagg cttgagccat ttttttgcca
    40441 aggtctatag cctggttggt atgggagttg ggctttctgc ctttgtttct tatttgatgc
    40501 tgtttccatt taggcaaaat ttagtctcga ttgttcttga tcatcctatg gtctattatg
    40561 gggcggctat tgttgagctt gtactggttt ttgttgctag tggtgctgca cgtcgcaata
    40621 caccagcagc tttaccctta tttcttgtct attcagcctt aaatggcttt accttgagct
    40681 tcattattgc agcttatgcg caaacaacgg tgctacaggc ctttatctca tcggcagctg
    40741 ttttctttgc tatgtcactg cttggtgtta aggttaagcg tgatctgtca ggtattcgaa
    40801 aggccatgtt tgcagccttg attgggatta tcgtggctag tctggtaaat ctctttatcg
    40861 gtagtgacct gatgagctat gtgatcagcc ttatttcagt gttgatcttt tctggcttga
    40921 ttgcttcaga caatcagatg atcaagcagg tctaccaagc ctctaacggt caggttggtg
    40981 acggctgggc tgtcgctatg gctcttagct tatacctaga ctttatcaac ctctttatca
    41041 gtctacttcg tctcttggga agaaatgact aatagctatt ttaagcgcag ctgctgattg
    41101 tcacttaatc gctattacga gaaatcagcg aagctgcagg tgttaccttt tgttagaaaa
    41161 gagtggctgc tgctagtaag aaagtagctg ctaggagagc ctgatgagcg tgactgtcaa
    41221 ggaaggccag ttactattgc taccatctag ggaaggtacc aaaaaaagtc aagaagcggg
    41281 cccaagggct cgtttttgtt tgcttgattt gtggtaaagt gcttcaaacc aagcctatat
    41341 ctagtctgat agctcttatc agctgacaac atcatattta caatgcctgt tggtgtagat
    41401 ttgtaaagca tgctcttttt tggtataatg agaggaacaa aaaatcgagg agaatatcta
    41461 tcaatatgtc tacagctatc tggatattat taatcattgt tgctcttaca gccggtcttt
    41521 ttggtgggat ttttattgcc cgcaagcaaa ttgaaaagga aattggagag cacccacgat
    41581 taacgcctga ggccattcgt gaaatgatga gtcaaatggg tcaaaaacca agtgaagcga
    41641 aaattcaaca aacttaccgc aacattgtca agcaatcaaa agccgcaatg actaagggta
    41701 aaaaataggt tacggattag aaatcgtggt ttctaagcaa tagctaagag tgaacagtct
    41761 ttgatgttaa aagcttgttt agagcttgca ttgtcagtta gaggtgtcaa ctgttcaggg
    41821 gttaacaata gactcagttg gctcttacca gctgagtttt ttatgcttca atgaggaaat
    41881 aatcgttatg gacaatagac caattggttt tttagattct ggtgtaggag gcttaactgt
    41941 tgttagtgag ctgatgcgtc agcttcccca tgaaaaaatc atttatattg gtgattcagc
    42001 aagagctcct tatggtccta gacctgctga acaaatcaga gaatatacct gggagttggt
    42061 tcgtttttta ttaacgaaac atgtcaagat gattgtcttt gcttgtaaca ctgcaacagc
    42121 tgttgcttgg gaggaggtca aggaggcttt ggatattcct gttttgggcg ttatcctgcc
    42181 gggcgctagc gcagctatca aggctactag tggaggaaag gttggtgtta ttggcacatc
    42241 aatgactatt tcttcaggca tttaccagga aaagatccag ttgctggctc ccactgttca
    42301 ggtaactagc ctagcctgtc ctagatttgt tcctattgtg gagtccaatg agataagctc
    42361 aagtgtggcc aagaaaattg tctatgaaac cttggctccc ttagttggaa agatagatac
    42421 ccttgttttg ggctgcaccc attatcctct tcttaggacg attatccaaa atgtgctggg
    42481 accacaggtt aaattgattg atagtggggc agagtgtgtg cgtgatattt ctgttctttt
    42541 aaattatttt gagattaatg gcagtcgaga tgatgaacat aggcgtcatc atttttacac
    42601 tacagccggc tcagacagct ttcaagcaat tgcctcagcc tggctaaatc aaacgataga
    42661 tgtggagcat gtgaccttat gagtgataac atttatgaat acaaggataa agacaattgg
    42721 tttattggca agatgacagg ccataattta atggctggct ggggggttaa ccatgagctt
    42781 attgccaaaa tagacgatat gttaggtgcg attgctggtg atgtggattg ggaaagtccg
    42841 gtcggttatg atgtgactgt tattcgttac gcctcccctt ttgccttgat tagctttgtt
    42901 gttggcatga tcaatcagaa agccaatcga gcccttaagg ttgttcggca ctcaggtgcg
    42961 attttagtga ccgaaaacga gcgattgctt gctgtgcata tgccagatga tggcgtccct
    43021 gtggctgact tctttggtca acaggcagat ggctttgggg atacgatttt gattgcgact
    43081 cgaaatgaag gcaagaccaa ggaatttcgc cggctttttg gtgatatggg atatcgcgtt
    43141 gaaaatctca atgattaccc agagcttcca gatgtggcag aaaccggggt cacctttgag
    43201 gaaaatgccc gcctaaaagc agaaaccatt tcaaggctta ctggaaagat ggttctggca
    43261 gatgattcag ggctcaaggt ggatatttta ggtggcttac ctggggtctg gtcagctcgt
    43321 ttttcgggcc ctgatgctac tgatgagact aataatgcta agctattgca tgagctggca
    43381 atggtatttg atcaaaagga tcgctctgct caatttcata cgaccttggt ggttgctgca
    43441 cctggtaaag acagcttggt tgtcgaggct gattggcatg gctatattgc aaccaagcca
    43501 aaaggcgagc atggctttgg ctatgatccc ttgtttatcg ttggggagac tggacgtcat
    43561 gcagcagagc tagctgctga tgaaaaaaac aagctgtctc ataggggaca ggcggtcaag
    43621 aggttaatgg aggtatttcc agcatggcaa gcaaaacaat cattgtgatg agcgattcgc
    43681 atggcgatcg tgaggttgtg gcagctatta aaggccgtta ccttggaaag gttgatgcca
    43741 ttttccataa tggcgattct gagctagaaa gctcagatcc tatttgggag gggattcatg
    43801 ttgtggcagg caactgtgac catgatagcg gctataagga tagcctagtc acctcctttg
    43861 atggcttgac tattgctcaa acacatgggc atttgtatca tattaacttt acttgggata
    43921 ggctagatta ttttgctcag gagactggag cggatatttg tttgtatggg cacttgcaca
    43981 gacctgctgc ttggcaattg ggcaagactg tctttatcaa tcctggctcg gtcgctcagc
    44041 cgcgtggtga ggtgaatgaa aagctgtacg cgcgtgttga atggacagca gcttgcatta
    44101 gggtggatta ctttacctgt cagcataagt cttacccatc actttctaag gaatttaaac
    44161 gatgatagca aaagaatttg aagccttttt aatcagtcat ttggatagct acctgattcc
    44221 agcagaggag ctagccattt ttatcaacac gcataatgct gatcatgtca tgctcttatt
    44281 ggttagcaat ggtttttcac gagttcctgt cattaccaag gaaaagcaat atgtcggaac
    44341 gatcagcatt tctgatataa tgacctatca agccaaaagg cagctaacag actgggagat
    44401 gacgcaaact aatattggcg acatggtcaa tacaaagatt gagaccatca atattacctc
    44461 tagcttgact gaaatcatgc ataaattggt tgattttccc tttttaccag ttgttaatga
    44521 tgacaatcga tttatcggta ttattacgcg taagtccatt ttgaaggcgg ttaatagcct
    44581 tttgcatgac ttcactgatg aatacacaat cacaaaaaaa tgatagcatt tattgaaccc
    44641 tttctagcaa gcaaatctct tgctaataac agccagcaat cctatcgcta tgatttaagg
    44701 cagttttgcc agcaggtcgg acagcgtatt aatcctgaaa ccctagccct ctatcagcaa
    44761 agcttgtctg gccttacggt agcagctaaa aagcgcaagc tttcaacggt caatcagttt
    44821 ttgtactatt tgtaccagca gaaggctttg acagactatt ttaaaatgga cgataggata
    44881 gaagcctctt tttctttgaa gccccagctg acaaggcttg acaccagcgc tttttatgct
    44941 gaaacagcct tcctaaaagg gcagctcatt gcgctgctga ttctggagct gggcttgacg
    45001 ccaagtgaga tagcagggct tcgtcttgct gattttgacc tgggtcttca ggtgctaagg
    45061 ttgcaatctc acagaggcat tcgtgtgatg accttatcaa aggccttgct gccatttttg
    45121 gaaaaggcaa cagaagctca gcagctctac ctctttgatc atgacgccaa gcccttttca
    45181 aggcaatggt tttttaacca gctcagagat tttttagaga gcattggctg tgcggagctt
    45241 tcagcccaga gtctgagaga gcaattcatt ttaaatgaaa aagcagccgg taaatccatc
    45301 attgaggtgg ctcagctgct ggggctaaaa agcccgatca ccttagaaaa atattataag
    45361 atgtaatgga tataaaagta aaagattttg aaggtcctct tgatttactc ttgcacctag
    45421 tgtcaaagta tgaggttgat gtttaccagg tgcctattgt ggaggtcatt gaacaatact
    45481 tggcctatat tgagaccctg caggcgatgc gcttggagct tgctggagag tacatgctga
    45541 tggctagtca gctgatgctc atcaaaagca gacgactgct gccaaagctg gtagacaagg
    45601 agcctgatga ggaggatctt gagcaagagc ttttgggtaa gattgaagaa tatagtcgtt
    45661 tcaaggctct gagtcaggag ttggccagcc agcatgacaa gagggctctg cttttttcca
    45721 agccaaagca ggagcttatc tttgagcagg ccgtcctaca aaaggataaa acagtcatgg
    45781 atttgttttt agctttttca cagttaatgg ctgcaaagca agaggccttt aaatataacc
    45841 atacggttat tgagcgagat gattatcgta ttgaggatat gatggagctt attgaagcta
    45901 ggcttgagct agagcaggag cttactttga cggatttatt gaagcattgt gatcatctca
    45961 atgaggccat taccttgttt ttagcaagcc tagaattaat caaacggcag cttgttggta
    46021 ttgagcagac atcacatttt ggccagattg ttttgcgaaa ggagatccaa tgacctattt
    46081 atctcagctg gaggccttgc tgtttgtcgc aggagaagaa ggactaagcc tacgtcagtt
    46141 ggccagccta ttagagttaa caccgacagc cttacagcag cagctcgaca agctttctca
    46201 gaaatacaaa gaggataagg aatctggcct gtgcttgatt gagtcctcta ggacctataa
    46261 gttagtcacc aaagagtgtc tggctccctt gcttaaagac tatgctaagg ctccaatcaa
    46321 ccaaaccttg tcacgagcaa gcctggaggt tttgtcaatt gttgcctata agcagccgat
    46381 tactcggatt gaaattgacg agattcgtgg tgtcaattca agtggtgccc ttagtaaatt
    46441 agtggccttt ggtttggttc aagaggctgg caaaaaggaa gtgattggtc gaccaaatct
    46501 ttatgcaaca acagattact ttcttgatta tatgggtatc aatcatttag aagagctggt
    46561 tgatatttct tctattgctg ttgaagagca agagacaacc ctgttttaaa ggcaaagagg
    46621 agcttgtctc atttgcagat aggccttatg ccctctacta gaagagataa cagtcctaac
    46681 aaggtatagt gcctgaaaat cctattgtcg ttatggacag cggtcttttt aggcatgcta
    46741 ttaataagag tagacctgtt taagctagtg agcttttacc cataggagag tgactggtct
    46801 gttggagcta tcatcagatt tcctaataag aaagagagaa ggataatgag aattaacaaa
    46861 tacatcgccc atgcaggcct tgctagccgt cgtaaggctg aagagctgat caagcgaggg
    46921 ctggtgaccc taaatggtca ggtgataaca gatttagcaa ctactgttaa atcaggcgac
    46981 cttgttgagg tagaggggat tcctatttac aatgaagaga aggtttatta tctcctcaac
    47041 aagcctcgtg gtgtcatctc aagcgtttca gatgataagg ggcgtcagac agtgattgat
    47101 ttgctgccgc aggttaagga gcgcatttac cctgttggtc gcttggactg ggatacctct
    47161 ggcttattaa ttttgaccaa tgatggtgat tttacagata aaatgattca cccccgtaat
    47221 gaaatcgaca aggtttatct ggctcgtgtc aagggagtgg taactaaaga aagcctgcgt
    47281 cccttaacac gtggtgtcgt tattgatggt aaaaaaacaa agccggctcg ttaccgcatt
    47341 attcgtgttg agcctgataa aaatcgctct attgttgaac taaccattca tgagggccgt
    47401 catcatcagg tcaagaaaat gtttgaagtg gttggacact tggttgataa gctatcaagg
    47461 acacagtttg gcagccttga tgtcagaggc ctaaagcccg gagaagccag aaggctgagc
    47521 aaaaaagaag tcagccagct acatcattta gcgagcacac gaaaatgatc aaagccctac
    47581 tcattgctcc tgtcagagcc tatcagaaat atatttctcc cttatttcct ccttcctgtc
    47641 gttatcagcc gacctgctcg gcctatatga ttacagctat tgaaaagcat ggtgctaagg
    47701 gtgttttgat gggacttacc agactattaa ggtgccaccc ttttgccgct ggcggagaag
    47761 acccggttcc agataccttt tccttaaaaa gacatttcat aacgcatgaa aaaatacagg
    47821 attttgacca aaaaactgat tgacaatagc agttaaagtg ctataatagc agttaagtat
    47881 tcgttggttt aaatcaaacc tgttatgatt taagttagcg agtcaccgtc aaccacattg
    47941 tttgctgagc atgactccgg gcagtgtggt ttttttgatg aaaagagtaa gcgggacaag
    48001 catgaaacaa gaaatcatta atagacaata tagggaaaaa gatagtcaaa accatgtggt
    48061 gctctttcag ccacaaattc cacaaaacac aggaaatatt gctaggacct gtgctgccac
    48121 caacacgcct ttacatatca tcaggcctat gggctttccg attgatgacc gtaagatgaa
    48181 aagagcgggg ctagattatt gggataagct agacattaga ttttatgatc atctagatga
    48241 atttttagca caatgtgatg ggagcttgca tgtgattagc aaatttgctg atagggtata
    48301 ctcagatgaa gcctacaatg atcgtcagtc tcattatttt ttgtttgggc gtgaggatac
    48361 tggtctgcct gagcccttta tgcgtcaata tgctgatagg gcactcagga ttcctatgaa
    48421 tgatgagcat gtcagaagtc tcaatgtctc taatgctgtt tgcatgatcg tctatgaggc
    48481 acttagacag caagccttta agggcttaga gcttagccat acctatgagc atgacaaact
    48541 aaaatcataa taagcatatc gcaaaacatc agttagattg aagaagtatc cgtaggggag
    48601 cttcttcagt ctttttttat tgtattcttt gcttattaac caagcagttg acacgaaaat
    48661 tccaatagat cgtttaaagc caataaaacc attattaggc ttgcattaca ggcaggtatc
    48721 aaagaaagat atagaaaaat ataccagaaa aaaatctcat aaaagtgtca aaatagtaaa
    48781 aaatcgccaa aaatatgtca atattatacc attattatag tataatattt ataatcatat
    48841 tataatatta aaatatctgg tgtctagctg tttttgtaaa agcaaaaaac ctgcaccacc
    48901 ttatgataaa gcataaagga atataagcat gatagtctac ctaaagcaac acaaaaatta
    48961 ctggaaatta gtcagcatag cagctttaat cattatttta ggaggaatac taacaatgaa
    49021 ttggcttaat ggggataggg acaataaagg cgagaataac tactatcaag tagagaagga
    49081 tttagcaatg gaaattgtta gtgagtttga aggagtaaaa gagattagct ttcttagtcc
    49141 agtacaatcc aaagaaacag ggtattgggg aacaacagct actataaata aaactaatga
    49201 gatatcttat tctttttcga tgactttttc aggaaagctt gatgattatt cttactatta
    49261 cgataaatgt tttaaattag tgaagcgtca caaaaaattg acattaagtc aagtggatct
    49321 aacagatatt gatattaaat attctaaggg agggaaataa atgataactg acaaaaacta
    49381 taactggcta gctggaaaag tatatgatgt tgatgctaat aaagtaacta ttcctgttag
    49441 aaaaaatacg gatattctta atcgttatgt caaagtcctt gaagccgaag acaatcctga
    49501 caacggtatg cagtttacgg tgtcaaagag taataggaat gttctagctt taaattataa
    49561 actaaggagc ttctatgaca gtaaaaaaga aagtcatcat tttattagga atggtagcaa
    49621 ttttagtaat gggaggtata tttatgttta gctataatca gaatcaagcg aaaatgttag
    49681 aacgacaatt taaccatgaa caaaaacgaa ttgtcttgta tttgttaaat cattatagcg
    49741 gaattaatga gatagaattt aatgatattg aaaacaacag tacaacaggt tctaagaatg
    49801 tattgctgac aataaataat aaaattaaaa tggaagttac attttttaat ttaaatgatg
    49861 atacagataa ctatgttatt agttggaatg ggaaattaag tttgatagac aaaaatccta
    49921 taactcattt aagttcaata gataaaataa aagtaaaata ttggagtaac aatgatagta
    49981 acagataaaa attataatga tatagccgat ggggtttata aggttgatgc tggcaaagtt
    50041 attagacctt ggcgaaacgg taagactttt aaaactaacg ggaaagatta ccgcgtcctc
    50101 aaaacagaag acaaccccga caatggtatg caggctattg ctgtagctcc gattaagggt
    50161 agtgaggtgg gtaagagtca tatcatgatt gtttatgtaa aaagcagcta ttggctagcg
    50221 tcctagcaat aaaaggagtt gatgatgaaa aagcaacaaa gcaaacgacg gaaactaatt
    50281 ggcatagtgg ctttaataac aattttagga ggaatactaa caatgaattg gtttaatgac
    50341 gaaaaactaa atagagagcg tagagaacaa gagagggcag ctatttattt tagtaataca
    50401 tatgaaaata tacataaaat aaagatcatc ggtatagata aaaatttaaa aacaggttct
    50461 atgaataaag ctacaattgt taatagtaag tactatatat ccgtaacgtt tatgggaggt
    50521 gagatttata caggtgtaga gcaagcttca aaagacaatg aggaattttt aaatcgtcga
    50581 aaaaaagcag agaataagac aaccttgagt aaggacattg aagttattta taaggagaaa
    50641 tagtagtggt tagtgataaa gattataata aactctctga aaaagtatat gatgttgatg
    50701 ctaataaagt aactatttct gttagaaaaa atacggatat tcttaatcgt tatgtcaaaa
    50761 tcctcaaagc cgaagatacc cccgacaatg gtatgcaagc tatggctgtt gt
//
LOCUS       DARYXZ010000009        50719 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYXZ010000009 DARYXZ010000000
VERSION     DARYXZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50719
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            175..963
                     /locus_tag="TV186_000442"
     CDS             175..963
                     /locus_tag="TV186_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1531871.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
     gene            972..2141
                     /locus_tag="TV186_000443"
     CDS             972..2141
                     /locus_tag="TV186_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL1531872.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            2144..2347
                     /locus_tag="TV186_000444"
     CDS             2144..2347
                     /locus_tag="TV186_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531873.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2479..3912
                     /locus_tag="TV186_000445"
     CDS             2479..3912
                     /locus_tag="TV186_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1531874.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3942..5110)
                     /locus_tag="TV186_000446"
                     /pseudo
     CDS             complement(3942..5110)
                     /locus_tag="TV186_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            5166..5807
                     /locus_tag="TV186_000447"
     CDS             5166..5807
                     /locus_tag="TV186_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL1531875.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            5928..6854
                     /gene="cysK"
                     /locus_tag="TV186_000448"
     CDS             5928..6854
                     /gene="cysK"
                     /locus_tag="TV186_000448"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL1531876.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(7241..7603)
                     /locus_tag="TV186_000449"
     CDS             complement(7241..7603)
                     /locus_tag="TV186_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1531877.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(7603..9003)
                     /locus_tag="TV186_000450"
     CDS             complement(7603..9003)
                     /locus_tag="TV186_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1531878.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(9036..9677)
                     /locus_tag="TV186_000451"
     CDS             complement(9036..9677)
                     /locus_tag="TV186_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1531879.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(9670..10674)
                     /locus_tag="TV186_000452"
     CDS             complement(9670..10674)
                     /locus_tag="TV186_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1531880.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(10671..11363)
                     /locus_tag="TV186_000453"
     CDS             complement(10671..11363)
                     /locus_tag="TV186_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1531881.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYIIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(11496..13391)
                     /gene="pknB"
                     /locus_tag="TV186_000454"
     CDS             complement(11496..13391)
                     /gene="pknB"
                     /locus_tag="TV186_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL1531882.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(13388..14128)
                     /locus_tag="TV186_000455"
     CDS             complement(13388..14128)
                     /locus_tag="TV186_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL1531883.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(14166..15488)
                     /gene="rsmB"
                     /locus_tag="TV186_000456"
     CDS             complement(14166..15488)
                     /gene="rsmB"
                     /locus_tag="TV186_000456"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL1531884.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(15478..16413)
                     /locus_tag="TV186_000457"
     CDS             complement(15478..16413)
                     /locus_tag="TV186_000457"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL1531885.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(16480..18864)
                     /locus_tag="TV186_000458"
     CDS             complement(16480..18864)
                     /locus_tag="TV186_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL1531886.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(18928..19245)
                     /locus_tag="TV186_000459"
     CDS             complement(18928..19245)
                     /locus_tag="TV186_000459"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL1531887.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARIEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(19270..19896)
                     /gene="gmk"
                     /locus_tag="TV186_000460"
     CDS             complement(19270..19896)
                     /gene="gmk"
                     /locus_tag="TV186_000460"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL1531888.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(20058..21668)
                     /locus_tag="TV186_000461"
     CDS             complement(20058..21668)
                     /locus_tag="TV186_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL1531889.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            21825..22310
                     /locus_tag="TV186_000462"
     CDS             21825..22310
                     /locus_tag="TV186_000462"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL1531890.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(22455..23906)
                     /locus_tag="TV186_000463"
     CDS             complement(22455..23906)
                     /locus_tag="TV186_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531891.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPEVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(23920..25074)
                     /locus_tag="TV186_000464"
     CDS             complement(23920..25074)
                     /locus_tag="TV186_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL1531892.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(25138..25506)
                     /gene="rnpB"
                     /locus_tag="TV186_000465"
     ncRNA           complement(25138..25506)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TV186_000465"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(25519..25842)
                     /gene="gpsB"
                     /locus_tag="TV186_000466"
     CDS             complement(25519..25842)
                     /gene="gpsB"
                     /locus_tag="TV186_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL1531893.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(25964..26479)
                     /locus_tag="TV186_000467"
     CDS             complement(25964..26479)
                     /locus_tag="TV186_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL1531894.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            26555..27163
                     /gene="recU"
                     /locus_tag="TV186_000468"
     CDS             26555..27163
                     /gene="recU"
                     /locus_tag="TV186_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL1531895.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            27150..29315
                     /locus_tag="TV186_000469"
     CDS             27150..29315
                     /locus_tag="TV186_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1531896.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(29358..30692)
                     /gene="pepC"
                     /locus_tag="TV186_000470"
     CDS             complement(29358..30692)
                     /gene="pepC"
                     /locus_tag="TV186_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL1531897.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(31381..32205)
                     /gene="nadE"
                     /locus_tag="TV186_000471"
     CDS             complement(31381..32205)
                     /gene="nadE"
                     /locus_tag="TV186_000471"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL1531898.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(32202..33662)
                     /locus_tag="TV186_000472"
     CDS             complement(32202..33662)
                     /locus_tag="TV186_000472"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL1531899.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(33938..35332)
                     /locus_tag="TV186_000473"
     CDS             complement(33938..35332)
                     /locus_tag="TV186_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1531900.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(35452..36369)
                     /gene="trxB"
                     /locus_tag="TV186_000474"
     CDS             complement(35452..36369)
                     /gene="trxB"
                     /locus_tag="TV186_000474"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL1531901.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(36429..36656)
                     /locus_tag="TV186_000475"
     CDS             complement(36429..36656)
                     /locus_tag="TV186_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL1531902.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(36766..37509)
                     /locus_tag="TV186_000476"
     CDS             complement(36766..37509)
                     /locus_tag="TV186_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1531903.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(37509..38312)
                     /locus_tag="TV186_000477"
     CDS             complement(37509..38312)
                     /locus_tag="TV186_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1531904.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(38689..39516)
                     /locus_tag="TV186_000478"
     CDS             complement(38689..39516)
                     /locus_tag="TV186_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1531905.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            40024..40479
                     /locus_tag="TV186_000479"
     CDS             40024..40479
                     /locus_tag="TV186_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531906.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            complement(41120..42463)
                     /locus_tag="TV186_000480"
     CDS             complement(41120..42463)
                     /locus_tag="TV186_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1531907.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(42546..43553)
                     /locus_tag="TV186_000481"
     CDS             complement(42546..43553)
                     /locus_tag="TV186_000481"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL1531908.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            complement(43555..45810)
                     /locus_tag="TV186_000482"
     CDS             complement(43555..45810)
                     /locus_tag="TV186_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1531909.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            complement(45814..46137)
                     /gene="ftsL"
                     /locus_tag="TV186_000483"
     CDS             complement(45814..46137)
                     /gene="ftsL"
                     /locus_tag="TV186_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL1531910.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            complement(46141..47091)
                     /gene="rsmH"
                     /locus_tag="TV186_000484"
     CDS             complement(46141..47091)
                     /gene="rsmH"
                     /locus_tag="TV186_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL1531911.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            complement(47194..47610)
                     /locus_tag="TV186_000485"
     CDS             complement(47194..47610)
                     /locus_tag="TV186_000485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531912.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            complement(47630..48877)
                     /locus_tag="TV186_000486"
     CDS             complement(47630..48877)
                     /locus_tag="TV186_000486"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL1531913.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            complement(48877..49695)
                     /gene="proB"
                     /locus_tag="TV186_000487"
     CDS             complement(48877..49695)
                     /gene="proB"
                     /locus_tag="TV186_000487"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL1531914.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            50296..>50719
                     /locus_tag="TV186_000488"
     CDS             50296..>50719
                     /locus_tag="TV186_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531915.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
BASE COUNT        14988 a        11590 c         9689 g        14452 t
ORIGIN      
        1 ctcctttggg agtctttatt ttgcttaatt ctttaagctt gattatatta taattcgaat
       61 taaaacgtat gtcaatagca tttacgaaaa aaatcgtatt tattttaaaa atactattta
      121 caaatacgat ttaaagcgat atcatatgag tataaaaatc gaaaggaaaa taatatggca
      181 agaggaagag gtagattaac acctcaagaa atagaggcgt taggattctt ttcgagcaaa
      241 ttcaatgatc tgctcaacga aacaaataca aagcaagttg aactctcaaa ggctacagga
      301 ataccaccaa gtacgctcac aggttacgta aaagggacat ctttacctat tcccggtaat
      361 gtccaaaaaa tagccgatta ttttgggtta atgaaatcag atatagatcc aagatttgca
      421 cctcgtaaga aaaatcacga acttaagatt cctacttctc cacttgtcaa aaaaataacc
      481 acaactgtcg tggaattaaa tgttcctcgt aagcaaaaag ttttagactt tgcaacagat
      541 caattaaaag aacaaaaaaa taaaatgact tctatggaga aaaaactcta tgagtataaa
      601 gtttacgaga agctttcagc tgggacaggt tatggatatt ttggtgacgg gaactatgat
      661 actgtctttt acgaagaaga attagactac gatttcgctt cttgggtttt cggcgattct
      721 atggagccca cttatttaaa tggtgaagtt gtgcttataa agcaaactgg ctttgattac
      781 gaaggcggtg tctatgctgt tgaatgggac ggacaaacct atattaagaa agtttatagg
      841 gaaaaagatg gattaagatt agtttcttta aataaaaaat acaaggataa gtttgctcct
      901 tttagcgaag atccgcgtat aatcggcaaa atcgtcggca actttatgcc caaagaatat
      961 tgaggtgtgt tatgggattg tttaatttcg gaaaaataaa agatgtggct ctagaaaaga
     1021 aattacaaaa gttacaacaa aaaattgaaa atgaaaaaga aaaattgagg gaaattaaag
     1081 aagaaattgc attagccaat gatacattag accttcaaga atatggtttt tttgaacgcc
     1141 agtataaatt ttcccatagt actaaatata aagatgcttt agatacgtta cgaatgaaac
     1201 aaaaaacact cataaaaaat ggtgaagcta caagcataat ttcccccatg actctagatg
     1261 gtagtgcagc aaaaggtaaa gcaatgcaga accaacttag gaaagctgca atccgcggct
     1321 ttaatggtga agccgatgcc ttactagtta aagtgtctgt cgtaaatgta gataaaaaag
     1381 tgcaaactct tcagaaggct ttcgaacaat taaataaaat gtatgaaagg aacttgatcc
     1441 aacttacctt taaatattta gatttaaaag cacaagaatt gagattagct gctgaatacg
     1501 aattgcaaaa acaagaagaa aaagaaattc taagagaaca gcgtgcaaga gaaagagaag
     1561 ataaaaaact tcaagctgag attactgcta aaagaaaaca acttgaaaaa gacaggaagc
     1621 actttttaca aatggtcaag aacgtcgaag tgatgcttgc taacgcttct ccgaaagaac
     1681 aagagaaatt acaattgcaa ttaattgaat accaaaacaa gctctcagaa cttgataaga
     1741 ttgaagaaga cattgattat agagaaggac atgcaacagc tggatatgtc tatgttattt
     1801 ctaatatagg tgcttttgga gaagatgttt ataaaattgg agtaacaaga cgtttagacc
     1861 caatggatcg tattcgcgaa ttggggagtg catcggtgcc ttttactttt gatgttcatg
     1921 cgcttatctt tagtgaggaa gcttttgctt tagagtctga gttacataat aaatttgaag
     1981 cgtataaagt aaataaaata aacagtcgaa aagagtactt tagagttccg tttgctaaaa
     2041 tcaaagaagt tctagaaaat cataaagaat tagctattga gattaccgaa gaagctgaag
     2101 cgtttgaata ccgtcaaagt atcttgaaaa atgggggtta aatatgaaat ggttattcct
     2161 aattttattt ataggctgcg gtgctaatgc tgtaaacctt tctaaaaaag ttaattccga
     2221 tgatgaagtt gacgaaaaca acagtcacct tatatcacat tcaaatgaag agattccttg
     2281 gaataaaaaa gaacagcttt attggggcac tgcttccatt gtatttttag tgctttttat
     2341 aatctaaaca caataataaa aagcctcacg ctcaactttg gtcgatgcga gcgtgaggcg
     2401 aacgtgtata gtaaaaacct gctttgcagt aggtctcttt actataccca ttttaacata
     2461 aaaatgaggt gaaaaacaat gattacaaca agaaaagtcg ctatttatgt tagagtcagt
     2521 acaacaaatc aggcagagga gggctattca atacaaggtc agatagacag tttgatcaaa
     2581 tactgcgaag ctatgggttg gattatatat gaggagtaca ctgatgctgg cttttcagga
     2641 ggtaagatag accgtcccgc catgtctaaa ctaattacag acgcaaagca taaacgattt
     2701 gatacaatct tagtttataa gctagacaga ctctcccgaa gtgtcagaga tactctttac
     2761 ttagttaaag atgtttttaa ccaaaacaat atccattttg tcagtctgca agaaaatatt
     2821 gacacttctt cggctatggg taatctattc ctcacattgc tatctgcaat tgccgaattc
     2881 gaacgagaac agataacaga gagaatgaca atgggaaaaa tcggaagagc aaaatccgga
     2941 aaaactatgg cctggactta tacccctttt ggctatgatt acaacaaaga aaaaggcgaa
     3001 ttgattttag atcctgcaaa agcgcctata gttaaaatga tatatacaga ttatctcaaa
     3061 ggtatgtcta ttcaaaaaat agtggataaa cttaataaga tggactacaa cggtaaggat
     3121 tgcacttggt ttccacatgg tgttaagcat ctattagata atcctgtcta ttatggtatg
     3181 acaaggtata ataataaatt attccccgga aatcatcaac caattattac aaaagagcta
     3241 tttgataaaa cccaaagaga aaggcaacgc agaagattag gaatcgaaga aaaccactac
     3301 acaatacctt ttcaggcgaa gtatatgcta agtaaatttt taagatgtcg tcaatgtggc
     3361 tcaagaatgg ggcttgagct tggcagacca agaaaaaaag aaggcaaaag atccaaaaaa
     3421 tactattgcc taaatagtag gccaaaacga acagctagtt gcgacacacc actttacgat
     3481 gcagaaacct tggaggatta tgtgttacac gagatagcca aaatacaaaa agatccgtca
     3541 atagcgagca gacaaaaaca tattgaggat cacgaattaa aatacaagcg tgaaagaatt
     3601 gaagctaata tcaataaaac agtgaatcaa ctctctaagc taaacaatct ttatcttaac
     3661 gatctgataa ctcttgaaga cctcaaaact cagacaaaca ctcttatagc taaaaaaaga
     3721 ttgctagaga acgaactaga taaaacttgt gataacgatg atgaacttga cagacaagaa
     3781 accattgctg actttctcgc cttgcctgat gtatggacca tggactatga gggtcaaaaa
     3841 tatgctgttg agctgcttgt tcaacgtgtt aaagttgata gagataatat agacattcat
     3901 tggacttttt aatgccaaaa attacaaagt tttcaaccct tgatttgaat aagactgctg
     3961 cttgtgtaaa ggcgatgatt ggctaataag acaaagacat ctacggttgg aaaggtcaca
     4021 cctctttcca aaatggttgt tgatataagt atagtgattt gtccttgtct gaattgctca
     4081 atgatagcca ttcgatttga tgactgactg gaagcatgag caatagtttc cttaggaaaa
     4141 tacttgtgga gcagctgaca gcattgctca gccagctcaa taatcggaaa aaagattaaa
     4201 agaggatagc cggttgccct ttgttttttg actagggtga tgaaccttct aggcaatttc
     4261 ccacgattga tagcctctaa aagggagaat aatctttgat actttggaac aactaagggc
     4321 ttgccatgga atcttcttgc caacgtcaat ttgacaagct ctttttgctg accttgcgct
     4381 ctaaatctct tgtagaggtt gctgttaggt atactgtcac tgcatctgct tttgcagcct
     4441 gatgagcagc atggtttaat tgacgattat tgacaaaggg gaaggcatct acttcgtcaa
     4501 taatgagcag atcaaaagca tggtaaaagg tcatcaattg atgtgttgtg gcaacgataa
     4561 tggggcttct atgataaacc tctgactcag catgcataag gcagacttga caggaaaagt
     4621 cccgcgatag tcgtttttca agctctatgc aaacatcaac tcgtggacta gcaatgcaga
     4681 cccagccacc cttattaaca actgctgcaa tagcttcata catcatctct gttttgccag
     4741 caccagtaac cgcatgaact aaggtgtctt gcttgagctt aacatggtta gtaagctgat
     4801 gagagatagc tgcctgatat gtcgtgagct gtccttgcca cctcagataa tgtccctttg
     4861 gaaaagaagc cggtggaaaa tagagcaagg ggcgatcaga ttggtttcga ccaaaaacaa
     4921 gacaggctct acagtagtaa gcaccgctag gcagctgatg agccttctca attaaactgc
     4981 tacagcgttg gcagtataac gttccctttt tagtgatcat gctttgtaag ctgcaagccc
     5041 aggcagaaac agcctttggg cattgccttt cgggtaaaag acgtccatag taattttcga
     5101 tattctccat accttattat ccgaattatt ttgctaaata tcagcatttt ttgtaaaatt
     5161 ttcttatgga agattataaa actattatga ctgatgggct ttttgaggaa agcatcaaaa
     5221 aatctcgctt tatttgccaa atcaaacgcg tctacacaga agaggaggcc agagccttta
     5281 ttgctgacat caaaaaaaag cactataagg ccaatcattc ctgctctgct atgattatcg
     5341 gagacaaagg acaaaccaag cggtcaagcg atgatggtga gccatctggt actgctggta
     5401 ttcccatgct atctgtctta gaaaggcagg aattaaccaa tcttgtagct gttgtgacac
     5461 gctattttgg aggtgttaaa ttaggagctg gagggctcat tcgcgcttac tccggcgtaa
     5521 ctgcggcagc tattcaggcc ttaaaggtcg ttgaggtaaa aaaacaaact ggactagcaa
     5581 tcagcctcac ctaccctcaa taccaaatct atcctaattt tctggagcaa gaagcattga
     5641 ttgaaatgaa taccgaattt tctgatgtcg tcagaacagc tatttacttt gatcctgagc
     5701 gcttggagag tatttctaag gcattgattg agcattatca tggcaaggtt tcctttgaag
     5761 agatcgaatc gcaaaggatt gaggtccctg ttttgcctgc caattagcat gaacagtgat
     5821 agcgtctctt tatcactacg atagtaaatg gctattttac tttgtcgatt attagctata
     5881 tacttttata taagcatgta ttgatacaag gataaaaagg aggacctatg tcaaagctat
     5941 atcacaacat tacagagttg gttgggaaaa cccctattat taaattgaga aacaccagtc
     6001 cagaggaggc tgccgatatt tatgtcaagc tagaagcttt taatccaggc tcttcagtta
     6061 aggatcgcat agcacttgca atgattgaag ctgctgagaa agcaggcatg atcaagccag
     6121 gtgatacaat cgttgagcca accagtggca atacagggat tggcttatcc tgggttgggg
     6181 ctgcaaaagg ctaccgagtg ctcattgtaa tgcctgagac aatgagtatt gaaagacgtc
     6241 aaatcattca agcttacgga gcagagctcg ttttaacccc aggtagtgat gggatgaaag
     6301 gtgcgattgc taaagcagaa gagattgcca gagagaccgg tgcttggatg ccctcgcaat
     6361 ttgacaatcc tgcaaatccc aaggttcatg aagagacaac agggcaagaa attatcgcgg
     6421 tttttggaga aaaaggactt gatgcctttg tttctggtgt gggaactggt ggcactattt
     6481 ctggcgttgc gcatgcctta aaggctgtta atcctgatat ttctatctat gctgtggaag
     6541 cagatgaatc tgccgtctta tctggtgaag agtcttctcc gcacaagatt caagggattt
     6601 cagctggctt tatcccaaat accttagata caaaggccta tgaccacatc attcgagtag
     6661 cgtcagaggc tgcccttgcc actgctcggt caatcggggc taaggagggc tttcttgtag
     6721 gcatttcttc tggagccgct gtttatgctg ctatccaagc tgctaaggag cttggaaaag
     6781 gtaaaaaggt cttagctata ttaccagata atggtgagcg gtacctgtct actgcccttt
     6841 atcagtttga ttagaataat catataagca ccagccctag cagctagaat aagctttcaa
     6901 gcataaatca tcgctcttac ttagtcacca ttaaaggcca gtcagctagc atatggaaaa
     6961 atgcttactt tgattccttt ttaacaataa acatagcata ccacgcctaa gcgccccaga
     7021 gcttctagct tcttggaaat aggctttcct agccgctttc accacagtaa aaaagactca
     7081 agctagtagg ctaagatgtt caaagaggac tagcaatcac aattggcttt ttttgaagat
     7141 agctttgaga taagtaaggt gactggtcca gagctgatag caaaaaaccg aggaacagtt
     7201 catatagctg tttctcggtt ttttatgttt ccaagtctgt ttacgatttt tcctgcttaa
     7261 agtggtctaa gccttcctca atccaattgg gtaagctggc ttcaagaggc ttaaagccaa
     7321 tcttataacg gctgtttgaa aagcgatgat gacttgacac atgatgcttt tcctcctcca
     7381 aagttctcaa ggacaggctg accttatgac tgtattcgtc atagtcaatg acctgaacta
     7441 aaaccgcctc accaagtctt aggatctgat gaatattatc aataaatccc gtcttaattt
     7501 ctgaaatatg aatgagacct gttgtcccat tttcaagggc aacaaaggct ccatagggtt
     7561 tgattcctgt aatggtccca tgcagcttat cgccaatttt catcaatcaa atacctcgat
     7621 ggcctcaatg acaacgtcct cttttggctt gtcttgtgcc cctgtttcga cagcagcaat
     7681 gttatccaag acctgataag aggcttcatc agccaactga ccaaatactg tatggcgacg
     7741 atccaggtaa ggagtccccc catgttcagc gtaggctgct gcaatgtcct ttggccagcc
     7801 accacgctct aattcctttt gagaataagg aaggcttgta ttttggacga taaagaattg
     7861 gctgccgttt gtatttggtc ctgcattagc catcgaaagg gctccgcgaa ggttgtacaa
     7921 ttcctctgaa aactcatcct caaagctttg accatagatg gattgcccac ccattccagt
     7981 gccagtcgga tctccacctt gaatcataaa atctgcaata atacgatgga aaataacacc
     8041 attatagtag ccttccttag ctagacctaa gaagttagca actgtttttg gagcatgctc
     8101 tggaaataaa gccaatgtca gctcaccatg atttgttttc atcaccactc ttggtccttc
     8161 atggccagcc aaatctagct gcggaaaatg taattctttg tcaatcaaac ctaattcctc
     8221 caaggcatat aaaatgccgt tttcttcaac tgttttagta ataaaatctg ctttttcttg
     8281 taattgtggg tgagaaaccc ccatagcaat gctgatgcca gcataatcaa atagctctaa
     8341 atcattgagc tcatcaccaa agaccaggat attttcaggc cttaagccca aatgctcaac
     8401 aacctttgat acacctagag ccttagaggt gccctttagg accacatcag aggagtgatc
     8461 atgccacctt actaggcgaa gctgctcagc caattcaaca ggtaattgca ggtcatctcc
     8521 cttgtcctca aaggtccaca tttggtagac atcatggtgc tcattgtaat ccgggcatac
     8581 ctctagtgtg gagtaaacct tatcaatagc atcactaatc atctcgttac gagctgataa
     8641 gacagcctcg tgacgtcctg ccatgccata atcaatgccg actgcattgg cccatttttt
     8701 ataggctaca acagtgtctg ctgggatagg tgcctgaaag ataatgtttt tttgattgtc
     8761 cttcacataa gcaccattta gcttaacaca ataatctgcc tgtaaatcct gaacctcctt
     8821 gggcacacca tatctggcgc gacccgaagc aattcctgtt aggatccctt ttttcttgag
     8881 ctctttgaaa accctctgga tagactctgg catatagcct gtgttcttta cgcgcagggt
     8941 atcatctatg tcaaagaaaa ccatcttgat tttcttggcc ttatacttta gttttgcgtc
     9001 catactttcc tccatgcaat agtactatta tagcattaat gatcatcttg aggcactaaa
     9061 tgatgtcgga aagcgtatac aacagcctga gtacgatcat caacctgcaa tttggctaaa
     9121 atatttgaca cgtgagtctt aactgtcttc aaggaaataa aaagctcatc agcaatggtc
     9181 tggttatcat agcccttggc caataaatgc aaaatatcgt attcacgcgc tgtaagctct
     9241 tcatgtaaat taggctgctg atcatgtgcc ttaatcttct tgtcaacctc cgtttcaatg
     9301 gcaagctcgc ccttagcaac ctttctaatg gcatttaaga tttcagctgc acttgatgtt
     9361 tttaacatat agcccttagc tcctgcatca atgacagggt aaattttttc attatcaaga
     9421 taggaggtta acaccaacac ccttgcttcc ttccatttgg agagtatttc tagggtcgcc
     9481 tctacacctc ctaattcagg cattaccaaa tccataacca cgacatctgg tctcaattca
     9541 agggcaagct caactccctc acgaccatta gaagcctcac ctatgacatc aacatcttgc
     9601 tgcaaattta agaagctttt taagcccatt cggaccattt catggtcatc aactaatatt
     9661 acggttatat tactcatctt catctcccat cacaagtggc agtctaatgt ccatcgaaac
     9721 gccctttcct ttttgactaa tcaaacgaag cgttccagcc aggtcattca cacgatcttc
     9781 aatattttta aggccatagc ttaattccct aacctgaccc atgtcaaaac caaccccatt
     9841 atcaaccatt tttagctgta gttctgttgg tgtttggttc aagtacacct caaggcggct
     9901 cgccttagca tgcttgaggg tattgctgat aaattcctga gcgatcctaa agagattatc
     9961 ctctatggcc tttggcagag tgccaatatt ttctttatag acaacctcaa tgccgctttt
    10021 atcagttagt tccttgagaa tcatcgtaaa gccctctgac aggctacgat ttgccaattc
    10081 tgtcgggcgc aggtgcaata ataaaatgcg taaatcattt tgagcatttt gcagcatggc
    10141 ttcaacagta actaattgtt gctgtagctg ctccttatcc atctgatcta ggctcataga
    10201 aacccctgac aaaatcatcg acgaagcaaa caattcttga ctaacagtgt cgtgcaggtc
    10261 tctagcgatt cgtttacgct cctgttgaac aattttttga ctatctaaaa tataagcatt
    10321 ctcttttttc tggatattgg ttgttatatg agacattttc gcagaaagtc tggtcaaatt
    10381 cgtgttgatt tcagaggtct cctccaaatg aattctttga ttgttgagaa tcctgcgtaa
    10441 atttttattg atgctccgct tgctattatc atctaaaata atccacaaca aaagcaacag
    10501 caaggttaca gagatgataa gcagcacaac tgaaaacacc aagcgctcta gctgccataa
    10561 atggctccgc aagtagtcaa aggtgatccc cagattatcc atcacaacaa aaacaattga
    10621 taaaatggtt atagtcgaat aaagccagac caaagcataa tacctttttt tcatcgtcta
    10681 gccacctcga catttcctgc tatagtggat acgataatct taaccttctt taaactgctg
    10741 tcctcggcct ctcctagggt gatggattca tttcgtaaat cgtactcttg aagctcaaaa
    10801 aaatcaacac tagcatagat agagctgacc tctaaggtaa cagccacatc aataggcact
    10861 aggatctttg tgttgccaaa gatctttctg ataatgatga cattgtccat tccagtcaca
    10921 atcacatttg tcagatcaat cgtatcattg ccagaggcac gaataatatt gatatcctca
    10981 aaggaataat aatcactttc atagttagct gcgccaagcc attgattttt gacctgtcgc
    11041 acagtcattt tttcttctgc aaaccgaatg agggcaaatc gattcttctt ttttacctgt
    11101 gaaaaatgat tgataatcac atacacaatc cccaacagaa ccgccataat aatataaggg
    11161 ttcagcataa aaattaagaa taaaagcaat aagctaactg ttagcaaaaa gctattgcgg
    11221 gtatcttgat tataaaaacg cagagccaat aaaatcaaga ccaaaattaa aataaagctt
    11281 gataagtcgt tggccaaaat ggtcataatc cccatagcca gcagcatgca ttcaacaagc
    11341 agaaagaatt gaaatttttt cattagactc cttccattac cctgacattt tatcaaaaat
    11401 taagcaaaaa ttcacccttg agtggcattc tagtaaaaaa gaatacctag cttagcaact
    11461 atgggcaagc cagatattct atatcctatt tacgtttacg gtgttgtaac agcgtcattt
    11521 tgacctaatt cggtatgact gcttgagtct gttgtatctc cagctgatgg attaggagcc
    11581 gaggtatcag agctcgatga gctgcttgat gcacgtgtct cctcagggta gaggtagagg
    11641 ctaatatcac ccttttcaga aaggctaatc tgggtaccat aatacggtgt ttgcccactg
    11701 acaaccgcct ttgagcttgg ggagctcacc tgcacaaagc ctgtcggaga gctggagctt
    11761 ggtacatagg ccttgattct tgcggcatca attcctaaag ctgttagtgt attgactgca
    11821 tctgcatagc tgtactcagt taccattggc atgatgactg tatcacccac tgctacactg
    11881 agggtaatct tggatttacc agctgggtta aatttttctc ctgcgcttgg agactggcta
    11941 ataacggtgt tttcagggta ttcatttgtc acgatacgct caatcttgat ttttgacttt
    12001 ggtacgccat aggtctcagt cagactggtc atcacatctt gataatcctg tcccttataa
    12061 ttttccatct caaagccttt atttccgatc gaaaggtaaa ggtcaacgct ggagcctttt
    12121 cgcttagctg agccagcttg aggatttgtc ttaaccacct gatcctcact aactgtgtca
    12181 ctttcaatct gatggacctt accgaccttt agtcccgcct cctccaagac ctgcttggca
    12241 gcattgagac tagagcctgt cacatcagga accttaaccg tagttggctt ggtcaagacc
    12301 aaataagcaa aaagagccac accaacaaca aaaaaggaaa acaagatttt taagagtgtt
    12361 cctagaaaac gcccattttt tttctttttt tgaggctttt gcagagtatc catctggcta
    12421 gtctgctcaa gtctagcatc aactgccgca gatgcctgac tagcatttga taccttaggt
    12481 gctgttacag gagtcggtgt tacctttggc aagggctttg tgctttcgac atcatcaaag
    12541 acaaccttac gctcacgact gcggttatag ctaagggctg tcatcaaatc cctgctcatc
    12601 tcaaaggtcg agcgataacg gtcacttagc tttttggcag tagcccgaat aacgacgttt
    12661 tccaaggctt gaggcacatt aggattttca tcaatgatag agggcagcgg cttttgaaaa
    12721 tgctgcaaag caatcgtcac agcgctatcg ccatcataag gaatatgccc tgttagcatt
    12781 tcaaagagca taattcccat cgcgtaaata tcactttgaa tcgtcgcttt agaaccacgc
    12841 gcttgctcag gtgagaggta atgcacactt cctagcatag aatttgtctg ggttagactg
    12901 gtctctgcaa aggcaacggc aatcccaaaa tctgtaacct taacaacact tgatttggtc
    12961 aaaagaatgt tttgaggctt taaatccctg tgaacaattc ctttttggtg ggccagagtc
    13021 atggcagaaa gaacctcttc catgattctc accacctcat tgttagataa tggcgcatga
    13081 tcctgaatgt attttttcaa gtcagagcca tcaacatatt ccattactaa aaattgctgt
    13141 ccgtcttcct cgcctatatc ccgaatggca acaatattgg ggtgatttaa ttcagccatg
    13201 gctcgcgctt ctctttgaaa acgcgcaaca gcaacctgat ctgtttgata attggtccgc
    13261 aagaccttaa tggcaacgtc ctcattatcc agaatcaaat cgtttgctaa ataaacatcc
    13321 gccataccac cgcggcctat agattttaga atgcgataac gaccagcaaa tagcttgcca
    13381 atctgaatca ttctgcttcc ccgctttcct tatgcaccaa agcaacggtg atgttgtcta
    13441 ggcctcctct ttggtttgcc aggtcaatca aggcttgatt tttctcatca aggctgatgt
    13501 cttgacataa tatgtcaaca atctcctcat tagcaatcat attggttaag ccatcactat
    13561 taatcactag gtaatcgccc ttttctaaaa ccttgacacc taagtctggc tctaccggtg
    13621 aagcttgacc tatagattgt gtgatgatat ttttttgtgg gtggctagca gcctcctctt
    13681 cggtaatctg accagccttc actagggcat taaccaagga atgatcactg gttaaaagac
    13741 tataatttcc ctcatgaacc aagccgatac gagaatcgcc aatatgggca taaatcgcat
    13801 tagaatctac tagagcaact gcctcaacgg ttgttcccat tcccttatag tcttcagatt
    13861 gtcccaagtc gtagatacgt tggttctctg cttcgatggt tgttaacaac caatccttga
    13921 tctgactaag ctcagtaaaa tctgtcttaa cccactctct acctaggtct gtaacggtca
    13981 tctcactggc aatatttcct gccctatgac ctcccatacc atctgctagg ataacaaggg
    14041 taatgccttt tttattatca aatttgttga taaaatcttg attgtttgag cgcttttgcc
    14101 caatatcggt ttttaatgaa atcttcatat aatcttttct gactaggtca gtctcctcct
    14161 aaatactaca agactcgtct gacttgccca ataaagaagc catcagtctg gtattgctct
    14221 ggtgtaatca taagacaacc gtccttgaca atatctgctt gtgcatgctt gagtgttact
    14281 tgttcaaaat taggatgacg ttgtaaaaat ttgtcaataa cttggaaatt ctcttcatca
    14341 aaaatcgtac aagtgctata ggttattata ccaccttttc gcagcgtttg acaaacgcta
    14401 gacaatatct ccagctgaat ttcctgcaat tgctggaagt cctgcccttc cttgttgtat
    14461 ttaatatctg gcttacgcct gatgaggcct ataccagagc agggagcatc aactaaaatc
    14521 ttatcaaagc tgttcttcgc aaaatgctta tgaacctctc tagcatcaag caccttagtt
    14581 tcaatccgat ctgctacccc tagacgctta gcattttcat tcactaaggc cagcttgtgc
    14641 tcatacaaat caagggccac tactttgccg ctcgtcaaat aagaggcaat gtgagctgtt
    14701 ttccctccgg gtgcactaca agcatctaaa atcatttcct gcccttgaat atccagcgtc
    14761 ggggcaacta gctgactggt ctcatcttgg atcgtaatgt ccccattgat gaaataactg
    14821 ctggcagcaa aattgccagc tctcttggtc agaccagtcc tagcaagtaa tgattgctct
    14881 gatcctgttg cctgcttgat ctcatcaagc tttgtcagat ctgtgacacg tatgctggct
    14941 ctgcttctca caaaaagact ttccatgatt gctacagctc gctcctcgcc aaattggtcg
    15001 atcaattttt tgactagcca gaccggtact gagtaagcaa cagcatagta tttgtttttt
    15061 cgcttgatgc tcttgatatc tggtaagggc ttattggtca gctggcgcaa aacggcattg
    15121 accagcttat ctgctcctct gccatgagct ctcgccttgg caagattaac agcgtcatta
    15181 acaatagcat gagcaggcac cttgtctagg taagccagct ggtaaaggct aagcatcaag
    15241 agataataaa cccatttatc cagcctgtct cggtcctcaa tatagtgagc cagataccat
    15301 tctagggtta tcttcctaga gatagtcccg taaacaatct ctgtgactag agccttgtcc
    15361 ttatcactta aaaactgatt cgccagctgg tgcttcaagg caaggttaga ataggctcca
    15421 tgatcaaaaa tatcctcaac gataagcagc gcctgtcctc tagctgattt tttccaatca
    15481 ttcgccaagg acatcaccca cctctaggct tctgccaata ccatttaaaa agtcaacaat
    15541 aggcatcttt ggcttgcctg ctggttgaac gagcgtcaag gatagagccc cctcacctgc
    15601 tgctacgacc aatgcttttt tagttttagc gatgatttgc ccagcagatc cagagccttc
    15661 agccaattca gcctcataaa ttttgaagcg ctgcccatct aataaggtat gagccaccgg
    15721 ccaagggttc attcctctga tatgattaaa cacctctctt gctggctttg accagtccag
    15781 tctttcttct tctgctgaaa gattgggaga aaaggtggct tggctatggt cttgaggaac
    15841 tggctttagg tcaccagaca agtaatcagg caaggttttc aataataaat ctcgtcctag
    15901 aatggccagc ttatcaaaca tggtaccaac attatcagta tctaaaattg gaaggcttgc
    15961 gcttgatatc atatccccag cgtccatctc cttaaccatc tccataatgg taactccagc
    16021 ttccttgtca ccattgataa tagcataatg gatcggagcg ccaccacgat atttaggaag
    16081 taaggacgcg tgcacattaa cagcaaatgt caccgaatcc aataagactg ttggtaaaaa
    16141 ttgcccaaag gctgccgtta caatcccgtc tgctcctaat gccatgatat ctgctagctc
    16201 ctgtgaacca gatagcttct caggctgaaa aacaggcagc tgatgtgcaa gcgccagctt
    16261 tttaacaggc gtcattgtga tgtctttttt gcgaccaacc gcacgatcag gctgggtcac
    16321 gaccgctaaa atgtcatagg ctggtttttc tagtaagccc tgcaaaacag ttgctgaaaa
    16381 ttggggagtg cccataaaaa ttaatcttgt catctatgtc ctctattttc tttctttttc
    16441 attatagcat agcttggcgc aaagtccggt aaagaacact tacataaagc tctgtggctc
    16501 ctgatcaatg ataaccttta gctcgcgatt atcctgctct tggctccaat caagaatttg
    16561 attcagggta gcttcaagct gatcctcaaa gcgatacttc aaaataatct gataatggta
    16621 aagattgtgc gttcttgcaa ttggctttgg cgttggccct aatattctga tctgatcaga
    16681 caagccctgc ttcaatatgg tcagcagttg ataggccttt ttgaccacct cttgctcact
    16741 cttatgcgat agggtcagac ctactgtgaa ataataggga ggatagccta gctttcgtcg
    16801 aatccccatt tcataagcgt aaaaggcttc aaaatcctgc tttttggcca gttgaatcgc
    16861 gtaatgctca ggattgtagg tctgaatcag gacttcacct ggcttgtctg cacgtcctgc
    16921 acgtcctgca acctgagtca gcaattgaaa ggttcgctcc gatgccctaa aatcaggtaa
    16981 atgcaaggaa gtatctgcat ttaaaacacc tactagggtg acgttgggaa aatccaaccc
    17041 ctttgcaatc atttgtgtcc caagcagcac atcagcatca ccatttccaa actggcttaa
    17101 aatagcctca tggcttcctt ttttacgtgt cgtgtctacg tccattcgta atattctagc
    17161 ttccggcaac acttgcttga gctcatcata ggctttttgc gtccctgttc cataatagcg
    17221 tatgcttttg ccttgacagc tagggcatag cttcggaata gccctttgaa agccgcaata
    17281 gtgacaattc atggttttcg tatccatgtg gagggttaag gaaatatcac aatttggaca
    17341 ttgatcaaca tagccacaat ctcgacacat gataaagcta gagtagccac gcctgttgag
    17401 catcaaaaca gcctgctctt ttctagcaag acgctctttg agtttatcaa tcaaataagg
    17461 ggtgaagctg ctaacctcct gctgaccaat ataatctcga aaatcaacaa tctcaacctg
    17521 aggcatactg gcaagaggat tggctctctc agtcagctgg ataaactgat acagtccctt
    17581 gctggctcta gcgcgactat caatactagg ggtcgctgag cccatcacta aggcagcctt
    17641 atggtgcctt gcacgaatga gagctacatc tctggcatgg tatctgggat tagattcctg
    17701 cttgtaggtg gcctcatgct cctcatcaat aataatggct ccaatatttt ctaaaggtga
    17761 aaaaatagca gagcgagcac cgaccaccac tctagcctgc cctgtcttaa ttttctgcca
    17821 ttcgtcaaat ttttctccat ctgacaaacc tgaatgcata atagcgacct gtcttccaaa
    17881 gcgggaaata aatcgagagg tcatttgagg cgtgagggag atttctggca ctaagacaat
    17941 agctgtcttt ccttgctcaa gcacatgcgc aatcacatga agatagacct ctgtcttgcc
    18001 agagcctgta ataccttcca gtaaaaaggg cttagcctct ctgccaacag ccttcgtaat
    18061 ctggtcaaca gcttgctgct gctgctgatt aagctttaag agtggggctg ccttgatgtg
    18121 attgaaataa tcctcactgc gattgacacg tcgctcctca agctcgatca gctggttggt
    18181 cacaaaatag ctaacaacct ctctagaata atcctgataa agcttggcta gcttatcttt
    18241 ttgtggattg gctaacaaat aagcctttaa ggcttggcgc tttttagccc gatttgaaat
    18301 cttatgctcc tgtaaggcta atctattgac ctgatagtaa gtctcggttt tgattgtctt
    18361 tttgtccttg gctagataag ttgccctaat cttaccagac tgtatcagcc taaggacacg
    18421 tccctcctgc tctggactta gcttagaata aagcaaggaa tccccattag agaaaacatc
    18481 agcaaggtca gccgcagcta agtcagctgt cggggtgagc agccgatcgt aatgagaatt
    18541 aagtaggcta ggaagcattg cctttaagag ggtgattttg taggaaaaga ctgtttgtcg
    18601 taattgctct gctaatgcca cctgctcctg atttaaaaca ggctcagcat ctaaaactga
    18661 ccaaatagcc ttcaattgct gcgttgattg actagaaaag ccaataacaa agccctgtag
    18721 caacctattg ccattaccaa aaggcacatg aacgcgagaa ccaatcttaa ccagagataa
    18781 tagctcatct ggaataagat aagaaaaggg cttatcggtt tgcatcaagg gaatatcaac
    18841 aatgacctgt gctatgtgtt gcattttgac ttcctttcta tcaagaaatg gacctgcaat
    18901 atgaaaaaaa ctaagattga ctcaacctta gattttttct ccctcttctt ctttttcttt
    18961 tgcaatctgc tcttttattt tacgctcttc ttcttctctt gctaaacgct ctgcctcaat
    19021 ccttgcacga acagccgcac gcttagcagc aggatccggg tgaatcacaa cattgcctga
    19081 ctcaatctcc tctagtgcct gaagtgttga tttgacagac ttaaaggact gtgtcggtgc
    19141 agcacctgct tctaattcat gagcacgctt ggcctgtaaa ataacaagtg aatattttga
    19201 tgggacttta tctaataaag tatcaattga aggttttaac atcatgggct ttactctttt
    19261 ctatttctat catctgagag attttgttgt tttaatcatt tgatcatagc gaccaatcac
    19321 acgctcaacg cgaaaatgct cggtctcaat aatacgcttg acacgctctg cagctaaagg
    19381 aacctcgtcg ttgaccacag cataatcata ctctcgcatg agcgcaatct cttccttagc
    19441 tctttcgata cgcttggcaa tcacctcttg gctgtctgtt ccacgaccaa ccaaacggtc
    19501 ctgcaattca tctaagtctg gcggcgttag aaaaatgaag acaccatcag gcaccttagc
    19561 cttgacctgc aaagcaccct gtacctcaat ttccaaaaag acatcaatgc ccttatcaag
    19621 ggtttcgtta acataggtta agggagtgcc atagtaattg ccgacatact ctgcatattc
    19681 tagcatttga ccatttttta ttagctcttc aaattcttct cgtgtgcgga agaaataatc
    19741 aaccccatca acttcacctg gtctctgtgg acgtgtcgtc atcgaaacag aatattcaaa
    19801 tttatgatct ggcgttgaaa aaatctcttg tctcaccgtt ccctttccga cacctgaggg
    19861 gccagagaaa acgattaaca aaccgcgttc agacattgtg ttctccttat tgattgcttt
    19921 ctaatagttt atcaaaaagg ctatcgtttt tcaagacaat tatcagccca atcctaagaa
    19981 agaaaaggaa gagatagacg ccttctcaaa gctagaggct aaactctggc ttttgaaaag
    20041 catacactct ttccttttta tttcgcataa tctattgctc gcaactcacg aataacagtt
    20101 accttgatat ttcctgggta atccaagtta ttttcaatct tttctcttac cttgtgtgag
    20161 agaaccacaa tctcgtcatc agaaatcttt tctggctgaa ccatgatgcg aatctcacga
    20221 ccggcttgga gggcaaagct actttgaaca ccatcaaagc ttgttgcgat ttcttcaagg
    20281 tcacgaagac gcttgatata gttttccaca gattcattgc gggcacctgg acgagcagag
    20341 ctaagggcat cagcagcagc taccagaact gcaataaccg aatccggctc gacatcgcca
    20401 tgatggctgg ctatggtgtt cacaacaaca gggtgctcct tgtacttgcg agcaaactcc
    20461 ataccaatct caacgtggct tccttcaacc tcacgatcaa tagccttgcc catatcatgc
    20521 aagaaacctg cgcgacgtgc aagtgccaca ttttcaccaa gctcgccagc taaaatacca
    20581 gctagcttac caacctcgac tgagtggcgt aaaacatttt gaccaaatga ggtacgaaac
    20641 tgtaagcgcc ccatgatctt aatcaaatcc gggtggaggt taggtgcacc gatctcatag
    20701 gcagcagcct caccatactc acgaatccta ttgtccatct caagacgatt tttctcaacc
    20761 aattcctcga tacgcgccgg gtgaatacga ccatcagcaa tcaaggactc tagggtcata
    20821 cgagcaatct ctcgacgaat agggtcaaag cctgataaaa caaccacttc cggggtatcg
    20881 tcaatgatca catcaatccc tgtcagactc tctagagtac ggatattgcg accctctcga
    20941 ccgataatac gccctttcat gttatcatca ggcaagtgca cacttgtaat cgtctgctca
    21001 gtcacatact caccagccat acgttgcatg gcctgtgcta acaggtcctt agcagtcttg
    21061 tctgtcctgt ccttgatgtc acgctctgca tcacgaatgc gtgttgcgat ctcatgcgtc
    21121 agcttgtttt cagtttccat caggataacc tcacgcgctt ctgcaatggt catagcagca
    21181 actcgttgga gctctgctct tttgtcttcc tcaagttttt caacctgtgc ctgtcgctca
    21241 tcaatgtgct tagatttatc ggtcagactt tgctctttgc tatctagtac tttttcttta
    21301 cttgatagat tttcatcctt acgatcaaga gttagagcac gctctgccaa gcgcgtctcc
    21361 agctgtttaa gctcttgtct ttcagattta aattcctgtt caatttcttc acgatacttt
    21421 cttgcctctt cctttgcttc taaaagtaat tctttacgac ttgctttact ttcacgttgt
    21481 gctgtctttt tgatatgagc ggcatcggcc tttgccttgc cacgaatatc aacagcatcc
    21541 tgttcagcgt ttaaaagagt caactctgca gcttccttcg cagacttgag tctaatcgaa
    21601 ataagtgcat aacctaatat tacaccaatg aggccacaga caagtaacgt tatgatatta
    21661 attaacatgt ctttacctca ataatagttt agttttcatt aacagaaagc catctcttag
    21721 tctatcataa aatgaagatt tagacaattt aaaatccacc tacatttttc taaaatctag
    21781 tgattttatg ttatgatatt gataaaaata aaaaggagtt tcttatgcca aaagaagtta
    21841 ttgttgaaag ctttgagctt gatcatacta ttgttaaggc accctatgta cggctaatct
    21901 ccgaggaatt tgggccccag ggagatgtga ttacaaattt tgatgttcga cttgttcagc
    21961 ctaatcaggc tgccattgag actgccggtt tacataccat tgagcattta ttagccaagc
    22021 tcattcgtca acgcattgat ggaatgattg attgctcccc ctttggctgc cgcacaggct
    22081 ttcacctcat catgtggggc aagcatagct caacagatat tgctaagatc atcacgtcca
    22141 gcctagagga aattgctaca agcatcactt gggaggacgt tcctggcaca accattgaat
    22201 cctgcggcaa ttataaggat cacagccttt ttgctgctaa ggaatgggca cagcttattc
    22261 tcaagcaagg gatctctgat gatccattta accgccatgt cacctcataa aacgaaagcc
    22321 tctcttttct gctaatgtga aggaggcttt taatgtattc aaaaaggtgc caaaggcaag
    22381 gctcaatgcc cttaccttta gcacctgtga taactagagt atccagttca ggatcacacc
    22441 ttgtcttcta agcattaata gtctaagtcc tctgcatgcc ccttgccatt tccgacaaaa
    22501 tagcctgttt tgcaattcaa tgaaaagagg taggtgccat caggcttaaa catgttgtaa
    22561 tagccattcc cattgataat attgaccggc tctaggatat aatcattgcc tgaaatatag
    22621 ccccttgctt gtgaggtagc cacaatacgc tcaagcacac ctggattaaa ggcccaagca
    22681 gggtttcctg tatcagcaat catagcctga ttgtagggca cacgagacag gtcacgctgc
    22741 aatattgaag ggtcatagcc tgtaatgcca tacattggag ccactggagc tggtacagca
    22801 ggaacctccg gagctgcagg gcttgctggt aaggcagaag cagctggagt gctagctgct
    22861 tgggtagcag acctgcttgc tagctgctca cgacctgcct tgatgcttga ttgtagcaat
    22921 gaatcaagtt ttgcattacc agtggttagc gtatcactag ctaggtcatc aaaattagca
    22981 tcagctttga cctcagctgc aatcttttca ccattgacaa ttgcagctgt tgtaaatttc
    23041 ccattaaccg cctgaatagc tgttacttgc tttttcagcc cagtaacctt ttccttagcc
    23101 ttgtcataat aggctgtccc ttcaagcctt tttaaagcag tctccaaatt cggtaactga
    23161 tcaaaggcgc tattttttag ggttgtttta tcattatctg tgaaaaatgt cttgtaaaga
    23221 tcttcaaaag ccttagcatt agcctttgtt ttgttggtct gattagctgt tgatgctttg
    23281 ctccttgctt ttttagaaac agtagccttt gactgaggct tatgcttaga cagctgatag
    23341 atatggttga gggcaaaggc tgaggctaca agggttagcg tggctaacaa aatagcaaac
    23401 agaggctttt tctttttaga cctacgacta gcatagctat ctgataaaat actctctact
    23461 tctgcaggtc gctcgctaac tgcgtcatca gctagctgcc cagtaaaatc actagcagaa
    23521 tcagtagctg ccgctgaagt gtcagctcta gctgctagag gctcaatgaa tgaggtctca
    23581 ccggctggct tctcctctgt tgaagcctcg tccactggct caacatcaac taagccggct
    23641 ttgctgagct cctctctttg ttttttgata aagttatcca gacttgctgt atctaactcc
    23701 atatactttg catcaaactt ttgtgatgac acttcgttac gatgccgctt aatatatttg
    23761 tctaaaacac tatcatcctc ggtaatccct gcttttagct ctgagtcctt gcgtactgcc
    23821 tcaccgattg tcattttttt ggcttcatga agctccaaat tttggctttc tgcctctgat
    23881 tcaaatgctt tgcttttttc tgacacgttt tttacctctc tatatcagat tgcgctttac
    23941 cctctctcca taaaattgat acaaatcaac ccttagagta ccattataaa gcttacgttt
    24001 tttatcagct ttttgaccat atttttgttc aaaatgatca tcactcgtca aaataaactt
    24061 gctccaggta actaatggag caaagacctg taccatctca ttatacaaga tgtctactgc
    24121 tttgtcatca agcaaacgct ctccataagg aggatttgaa atgatgacac cgtttatctt
    24181 gtctgtacgg aaatcctgca agcgcatttg cttaaaggta atgatatcag ccaagccagc
    24241 ctcctcagca tttctcttgg caagctcaac catacgaccg tcaatatcaa agcctgaaat
    24301 atccagctca atatcataat tagcctcttt ttcagcagcg tcacgaacct tttgaacacg
    24361 atctttgtcc acccagctcc attcctcaaa ggcaaaggag cgattaaagc caggagcgat
    24421 attcattccg atgagagccg cctcgataca aaaggtcccc gatccacagg tgggatcaac
    24481 caagggctta tccggaaacc aattagacag cttgaggata gctgctgcca tgttttcctt
    24541 aataggagct cccccttttt ccacccggta gccacgctta aataggcttg agccactagt
    24601 atcaatcatc agggtagcct gatcctttaa gattgagacc tcaattttga actcagcccc
    24661 cacctcttga aggggaatat gctccggtct atgaaaatgc tgctgcaatt ttctgacaat
    24721 ggcttttttg gtaatggctt gaacacttgg ctcgttgtgc agggttgacc tgacacactt
    24781 agcctttgca ataggaaacc tagcacctaa gggcaaataa tgctcccaat ccaaggcaaa
    24841 tacgccctga aacagctcct caaagcttcg tgctgggaac tgacctacaa taatcttaat
    24901 acggtcagcc gctcgcagcc aaagatttgc tttagcaata gcttcaatat cgccttcaaa
    24961 gaagaccttg ccattatcta ctcggcagtc aaatcccaag gcccttaatt ccttacccac
    25021 aacagcctct aggccagctg ctgcagttgc tactaatgta aattgttctt tcatatgact
    25081 ctttctatcc taaccaaata aaagctagca tatgctagct taacctatta tgcaattttc
    25141 tataagccat gttttgttcc agaaataact aggtattatc tccttcgata atcatctgtc
    25201 tactgtttgt caacagtcag gatagcttgt tcgtttccaa ctatcccatg cccctaccaa
    25261 agtttgggtt gctagcttga ggggtttacc gcgttccact ttttacgttt ccataaaaac
    25321 ttcgtcactg tggcactttc agagctactc tggcatatca aggacttagc cttttcactc
    25381 gccgtaatgt gtcaaacaca tccctaggct tatttgttcg cctagcacaa acactaccag
    25441 catcacagcc ggtgctagca tggactttcc tcatagtatt gcaatactac gcgattatcc
    25501 aaaaattgca catctacatt actcaataat ttgctttcca aaaacctctt tttccagctt
    25561 gctaatgcgc tttagcatgt caaaattggt ggctgactgt gctactctgg ttggctgtga
    25621 taccgcctga gagctgcctg ctaaaggatc acgcacctga gccttagcct tttttaaggc
    25681 ttcattttca gcctttaggg cctcgatctg agcattgaaa tactcataat ccttgatgac
    25741 gttatcaagg aattcgtcga cctccttctt atcaaagcca cgcatactgg tcttaaattc
    25801 ttgctcaaaa atgtcctttg gactataaat tatacctgtc attctatact ctccaaacgg
    25861 tcaatctttt tcaaatatca aactttgata tcactactta tggtacagaa aaataaatta
    25921 aaaagcaagt atttaaatac cagtgatttt taaatatcac tagctactca tctgcaatgt
    25981 catttaaacg ctcaaagttt aggaaagaaa gggggtaaca gggctgctcc ttcatagctg
    26041 ctaccaaata gcttaggcgc gtttcgtgct cactatcata aaaaagatag gctccgtctg
    26101 tattgtgaat caaaaagtga tggtagctct ttagctgttt agggctttca tagctgggat
    26161 agctatattt gacaaaatca gtctcccgaa attgctgcag ctgctgctga ttgcgatcat
    26221 tccaagtgct gccatgcgtt tcaaaggcaa aaatagtcgc tgtctttaag gggtaggtct
    26281 ttttgaggtc attagctacc tctaaagccc actgctcaaa ccctaaattc ccagtaaaaa
    26341 taaaccagtc taccccctcc tcaagataag caatcagatc tctttctatc gcttttttga
    26401 taatggcaac tcttttatcc ttttcactaa agatgcccag ctcaaaactt cgatagcctg
    26461 ttacgagaat tgcagtcatt agatgttatc ctttcaaaaa tatgttataa tgtgaatgct
    26521 taaattatta ttaagtcatg atgttaggag aacaatggtt aactaccctc ataatcctat
    26581 tcgccaaaag gtgacccctc ttcaaaagca gcaaaagcac aagcaagtag actttgctaa
    26641 tcgtggtatg tcctttgaag catccattaa tgcaaccaac gcttattact tggccaaggg
    26701 cattgctgtc attcataaaa agccaactcc gatacagatt gtcaaggtag actatccaag
    26761 acgtagtcga gccaagattg ttgaggctta ttttaagcag gcttcaacga ccgactattc
    26821 tggtatctac aaagggcatt atattgattt tgaagctaag gaaacaagac aaaaaacagc
    26881 tatgccaatg aaaaactttc acgcgcatca gattgagcac atggctgctg ttttaaagca
    26941 aaaaggcatt tgctttgtcc tccttcactt tgcgacacta aaggaaacct attatctacc
    27001 tgccaaagca ctcattgatt tttatcagat tgataggggc aacaaatcaa tgccacttga
    27061 ttatatcaga aaaaacggct ttgaggtcaa gctgggagca tttccacagg ttccttattt
    27121 agatattata gaacaaaaat ttttaggcgg tgattacaat taacaatcca aaaatcctta
    27181 aattcctgaa gtatacatta ggtgctatcc ttagccttat cattgtgaca attaccttag
    27241 gtggcctttt gtttgcttac tatatcagca gtgcccctaa gctttctgag gcccagctca
    27301 aatcgaccaa ttccagtctt gtttatgacg gtaataatca tttgattgct gacttgggct
    27361 ctgaaaagcg tgaaaatgtt acagctgaca gcattcctat taatctggtc aatgctatta
    27421 tttctataga agacaaacgc ttttttaatc atcggggggt tgatctctat cgtatcttag
    27481 gtgcagcctt tcacaattta acaagcaaaa caacccaagg ggggtctaca cttgatcagc
    27541 agctgattaa gctagcctac ttctcgacaa acgagtctga ccagaccttg aagcgaaaag
    27601 ctcaggaggt ttggctggcc cttcaaatgg agcgaaaata taccaagcaa gaaatcctga
    27661 ccttctacat caacaaggtt tatatgggaa atggtaatta tggtatgctg acagcagcca
    27721 aggcttatta tggcaaggat ttgaaagatt tgtcctatgc tcagctagcc ttgctggcag
    27781 ggattccaca ggccccaagc cagtatgacc cctacacaca gcctgagaca gctcaaagcc
    27841 gccgaaatat tgtccttcag caaatgtatg ctgaaaagaa cattaccaag gctgagtacg
    27901 aagcagctat cgccacacct atatcagaag gcctacagcc tctccagcaa cgcgccagct
    27961 atccaaaata tatggataat tacttaaaac aggtgatcga gcaggtaaag gctgagacca
    28021 acaaggatat ctttacctct ggtctaaagg tttacacaaa catcattcca gaggctcaaa
    28081 aaaaacttta tgacatttac aattctgagg actatgtgta ttaccctgat gctgactttc
    28141 aggttgcctc aaccgttatt gatgtcacaa atggacacgt tatcgcccaa ttaggaggac
    28201 gcaatcagga taccaacgtt tcctttggaa ccaatcaggc tgtcttaacc gatcgtgact
    28261 ggggatccac catgaagccg atcacagact atggacctgc cattgagtcc ggtgcttaca
    28321 attctacagc tcaaacaact aacgactctg tctactattg gccggggaca cacactcagc
    28381 tctataactg ggaccggaga tactatggtt ggatgaccat tcaagctgct ctcatgcaat
    28441 cacgaaacgt ccctgcagtt agggctctag aggcggcagg tcttagctat gcacagtcct
    28501 tcctcagtga tctaggcatt aattatccag agatgcatta ttcaaacgcc atctcaagta
    28561 acaatagcag ttctgattca aaatacggtg caagcagtga aaaaatggct gctgcctatg
    28621 cagcttttgc caacggtgga ctctattaca agccacaata cgtcaataaa attgaattca
    28681 gcgatgggac cagcaaggtc atcgaaaata agggcaagcg tgccatgaaa gaaacaacag
    28741 cctatatgat gactgatatg ctaaaaacgg tactaaccta cggtacaggt actgctgctg
    28801 ctatcccagg agttgcacag gctggtaaaa ctggtacctc aaactatacc gatgaggagc
    28861 tggcacaaat tgttgagaca catggactat ctcctgatta cgtgggaaca atggcgccag
    28921 atgaaaactt tgtcggctac accaaccgat acgctatggc ggtttggact ggttataaaa
    28981 accgtatgac gccaatttat ggctacagcc tagaaattgc ttctcatgtt tatcgcaaca
    29041 tgatcagcta tctcaccggc ggctacagcg acgattggac catgccaagt gggctctatc
    29101 gtagcggcgg cttcctctac ctaagtggta cctatacaaa cagtagcgat tatacaagct
    29161 ctgtctacaa caacctctat ggtaataaca gctcagcttc aagccaatcc tcagatgagg
    29221 atacaactga agacagccac tcagaagcaa acgacagcac aacgtcatca tcagagcagc
    29281 aatcaagctc caccgatgat aagaaaacca actgataaca aaaaactggt tcaaatgttc
    29341 tgaaccagtt ttttcaatta tttggctaag gcacccatcg gatcccaagg ggcaagtacc
    29401 tgtggttctg cctcataggc tgctaattca tcagctgtta gtaggtcctt gcgaacaaca
    29461 atctggtaag tatactcgtc catccaagca tcagaagcaa caaagtatcc tttgtcacca
    29521 accttgtctc cccaagaatt ttcaaccttc catttgatag gcttaccagt atcatctaaa
    29581 tcaacacctg tcaaaaccat agcatgtgtc attaagcttt cgctgtaatc aaggcgacca
    29641 gccttgtctt ggctcaactg aatatccata cctgcctgaa aatcataggt attaagggct
    29701 agaatcccct tttgacgatc tgatacctga ccaacgtctg aaccaaacca aacggactct
    29761 ccagcctgca tttgcttaat agcaagctcc ttgaagcgct ccatatcaag attaaggtag
    29821 cgcacctcag gactgccaac aacattacca agcatatcaa ccgtataaga tttgccataa
    29881 ggcttatcag ctgttggggc gttgataaca gacacataat cagacagctt tagaccaaca
    29941 tatttttcat aaaatgcctg tggtgtgatg cccttatcag catgatagtg attatcctta
    30001 tcacgataag caaaatcaaa ttgacgaggt ggcaaaccaa gattcatggc taagaaatta
    30061 aagatttcct gaagtagctc ttctttttta gcctgtactg cctgatgatc agcaccagca
    30121 ctgatcacat ctcgaagaat ctgagcgtcc tgacgcaaga gcttattgag gtattgattt
    30181 agctcacgac tattgcttga tgacacagac tctgggtaga ctgattttgg cacaacaccg
    30241 tatttttcaa acagggctac aaccatgtcc cactgaccac cgtcttgctg cggaacgtcc
    30301 aaaagaaact taaccctacg gctagtcaag gcttgatcag cagttgcaat cacctgttcc
    30361 ataaaccagt ttgatttttc gtatttgtcc cagaaaaagg tgtgtgcttg tgacaactca
    30421 aaatcttcta atttaaattc tgaaataagc ttatggcgaa aggtgtttaa ggctgcaaac
    30481 atccagcaac gacctgaagc cttttgatta gagaccttat cctttgtcaa gtcaatggaa
    30541 aagacaaaat cattgtcgat ctcactttgt cttgtctcca aggatttaag caagccattg
    30601 tgagtgatgg cattttcaag agctaaatat ttagcattag cttcataatt agcatatagc
    30661 tgttctgtaa atgtctctgt taatactgac atcattttcc tccaaagata ataaataaca
    30721 acacctaaaa ataaagttga cagaaaaatc cataaatact gtcaatttca ttttcaagga
    30781 ttacttctat tatagacctt atttgatatt cttcaagtaa aaaaattagg ctaacttaat
    30841 tttttaaagc taagcagcag ctttccaata accagacaaa aagccatctc aaaagacgac
    30901 aaaacctgct ggactttgag cacctaaaca tgtcatatgt ccacctcagc atgaactcaa
    30961 agaagctagc tgtgtctggc tatgacttca gtttaatcat tagcttgcct tagccacaaa
    31021 aagaatcgtc tccactgtag caaaagtgct tgatataaca ccatcggcta agtcaagggg
    31081 cccctgatag ttaactgaaa catatggcaa agctaaaacc aaagacttct tctccttaaa
    31141 gcctctggtt tttagttagc tgagcattct cctttatctt ggctgcttta agatagggac
    31201 aaatcaacaa ctaccccaat cccatttaca aaaaagccct aagtcagagc cttcataggg
    31261 ctaagggtga gggaagctct taggcaacag ctactggatt tatgcctaat agaagctcct
    31321 gtccctcctc acctatttaa aatagcattg gtttatctat agcctgtgta ggtttgagga
    31381 tcacttccaa aagtcatcaa aaatagtaat tggcagatgg cgcttgtgct gccctttatg
    31441 ccaccagtct tcaatccttg cctgagcttc agcggaaatc gtatgcccct ctaagtaatc
    31501 gtctatctct tgataagtaa cacctaatgc tacctcatct gcaagtcctg gcttcttatc
    31561 ctctagatct gctgttggca ccttctcata gaggctgggg tcagccttta gcacctttaa
    31621 caaggcctta ccctgccgct tagtcaagcg aaaaaggggt agaatatccg ctccgccatc
    31681 accaaactta gtgaaaaagc ccgtaacatt ttcggcggca tgatctgtcc caatgacagc
    31741 accagctgtt tgaccagcga tagcatactg actaatcata cgctgacgtg ccttaatgtt
    31801 tcccttatta aagtcagaaa tctcaagccc tgccgcctct aaggctctta gctgaccatc
    31861 aacagcctct ttaatattaa ccgtcaaggc ttgatcaggt tgaataaatg ctaaggcttt
    31921 ttgtgcatct gcctcatctg cctgaacacc atagggcaag cggacagcga taaattggta
    31981 ctgctcatca cctgtttcag cgcgcagctc ttcaatcgcc atctgagcta gctttccggc
    32041 taagctggaa tcctgaccac cagaaatccc taagacataa gtctttaaaa aagggtgctt
    32101 taacaaataa gcctttaaaa aatcaaccga ctggcgaatc tcctgcttag gatcaattac
    32161 tgctttgacc tcaagctgac gaatgatatc ctcttgtaat gtcatatcaa atcactcctt
    32221 ttacaggctt ccttgcggat tttgtcaata agatgcatct tattttgcca aacatcaagc
    32281 gcaagatcca cagggtaatg ctgcggattc aagacacgct tatattcgtc ccaaagctta
    32341 tcaaattcct ttctagcata agccttgatg tcttttaagc ttggcagctg ataaacgagc
    32401 tttcctttat caaaaatatc tactagcaaa ggaacagcat caaaatctct gacggtttta
    32461 ttaatgtagg tataagtcgg gtggaacatg tgaatttcct ctaggtcatt gacattaaca
    32521 cctgtaaagg tgatgtaatc gccttctgac ttgccctttt cgcggctggt aattcgccaa
    32581 acctgctttt tacctggtgt tgataccttt tctgcattat ttgatagctt gatagtatcg
    32641 cgcatggtac catctgcctg ctctatcgaa acaatcttat aaaccgctcc cagagctggt
    32701 tgatcatagg ctgtaatcaa ttttgttcca acaccccaaa cgtcaatttt agctttttgc
    32761 attttcaggt tgagaattgt attttcatct aaatcattgg aagcgtaaat cttagcctct
    32821 gtgaagccgg cagcatccag ctgctggcgt acccttttag ataggtaagc aaggtcacca
    32881 gaatccagac gaacacccaa gaaattaatc ttatcaccta attccttggc cacacgaata
    32941 gctgttggga cacctaccct caaggtatca taggtatcaa ccaagaaaat acaatccttg
    33001 tgcacactgg cataggcctt gaaagcatca taatcattac cataggcctg taccagagca
    33061 tgtgcatgcg tgccagacac aggaatgtca aaacgctttc cggcacgaac gttactagtt
    33121 gcgtctgctc cgccaataat ggcagcacgt gtcccccaaa cagcagcgtc catctcctga
    33181 gcgcggcgtg tcccaaactc taaaagtggc tcatcttcaa taacagagcg aatacgagct
    33241 gcctttgtag caatcaaggt ttggaaattc acgatattca aaagagctgt ttctactagc
    33301 tgacattgac ctaaaggtcc ctcaacctga acaataggct cattggcaaa gaccaagtct
    33361 ccctcttgtg ctgagcgaat cgttagctct aaacgaagct ctctgagata ggtcaaaaaa
    33421 gcagggctgt agcctagctc cttcaaataa gccaaatcgg tctcagaaaa ggtcaattgc
    33481 tcaaggtatt ctacgattcg ttgtagacca gcaaaaactg catagccatt gttaaaaggc
    33541 tctctacgaa aataaacctc aaagacagca ttacgattat gaatgccctg ctcaaaataa
    33601 acctgcatca tatttaattg atataaatca gtatgaaggg ttaagctatc atctctgtac
    33661 atataagtaa ctccttaaca taattgttat tattatacca tatttttggc atagacctgt
    33721 aagattcaac taaaatcctc tgctcaagct ttctaaaaaa gaagccttga gctgctatta
    33781 agcctgacat attttttgcc agtaccttcc taaaaagtct atagcacaag ggcttatggc
    33841 tttttaacaa aagcagtttc agttgatagc attcataaaa aaagattgaa gaaattgacc
    33901 aaaatagccc ctttcttcaa tctatttaac tcacacctta gccttttaac gcttttttac
    33961 acttgagctg actgtagcag ccaaagacta gaatccaaat gctagcacca attgccccga
    34021 tataggtgga cttctgtaaa aacagtgaaa taaaaacaaa ggcaaaaaag gctagggtca
    34081 atggtgttgt tagctgataa cttggcatca aataaccatc tggcataaag tcactggact
    34141 gacgatattt ccaatgcgca agcatggtca aagcataaat cgcaatataa acaccagatg
    34201 atgaggccgt aatcagcgaa aaggcatctg caacaccggg caggatatta atcaaggccg
    34261 acaccccaac agcaacagca gaagcaataa tagccctact tggtacccct tgacgagata
    34321 gggtgttaat cctcaaggct ttagtaagag catttggggt ctcattagcg atttgataca
    34381 aatgccgacc tgtcgaatac agggtcgaat ttagggctga tgctgctgat gttaagacca
    34441 caaaattaat taaagcagca gcccatttaa tcccaatcag cttaaagacc atcacaaagg
    34501 gagactcgtc cgtaggcaac tgataccaag gcacaatcgc cataatagac accaaagcac
    34561 caacgtaaaa aatgacaatc cgcatcggaa tctcttggat ggccttgggc aagacctttc
    34621 taggatttgc ggtctctgag gttgtaatac caacaaattc gatggcctga taggcaaaga
    34681 aaaccatctg aaaggccatg aaaaatttca acttcccatt cggaaatagt gaaaaatgat
    34741 ccacaatatt ggcaaggctg gcatgaccga catgcgtttc aaagcccgtt agaaccataa
    34801 aaacggctgt tgcaatcaag gctaaaatcg caacaatctt aatcatggca aaccaaaatt
    34861 cagtctctcc aaagacccgc acagcaatta aattgatgga gctaagcaac accaaaaaaa
    34921 cgagctgaat cagccaagat ggccaagcag gaaaccaaaa ctgaacatag gaggcgacag
    34981 ctgtaatctc tgccatgcca ataaagatca gggaaatcca gtaagaaagc ccagaaaaat
    35041 agccccagcc tggcccaata tattttgtaa tgaaattgat aaaggtatgc tgatccggat
    35101 catagtatag catctcacca atagcccgca tcatcaaaaa cataaagaca cctgtaatca
    35161 tgtaaacaaa gataatagac ggacccgtta aggcaataga acgaccagct cctagaaaga
    35221 gacctgttcc aatagtgcct gctatcgcaa tgagctgaac atgtcggttt tgcagccccc
    35281 ttaccatgcc attctcaagt tctttagtgc ttttagcttc ttttgtagac atttgactct
    35341 ccattcaatt aaaaaaacac cactattata tctgtttttc agaaaatgtt caactttctc
    35401 taaggcttgc aaactaaaaa ggccaaccaa gcctttttag cgttaacctt tttaagatga
    35461 taggctttca atgtaatggt agacgccttg accggcaatg gcaccatctc caactgctgt
    35521 tgtgatctga cgcagctgct tttgacgaac atcaccgaca gcaaaaatac caggaatact
    35581 tgtcttcatt tgatcgtctg tcacaatcca gccctcttga ttggtaatgc ctagctcaga
    35641 taccatttga gtaaccggaa tcaagccgac atagataaag acaccaccaa agtcatggct
    35701 agtcacttga cctgttttga cattttcaat cacaacatta gagaccttaa tatcgtttcc
    35761 ttgaatctcc ttgacaacag aatcccagat aaaatcaagc ttttcgttgg caaaagcacg
    35821 ctcctgcaag atcttttggg cacgcagctg atcacgacga tgcacaatcg ttactttctt
    35881 agcgaactgg gtcaggtaga tggcttcctc aactgctgaa tctcctcctc ctacaactaa
    35941 taactcctga ttgcgaaaga aagcaccatc acagaccgca caataagaaa cacctcgact
    36001 ggtgtactcc tcttctccag caacacctaa aagacgatgc tttgctcctg tcgcgacaat
    36061 cactgtttta gtatcgtagt gcgtatcttc tgtgtacaca cgcttataat caccacaatc
    36121 ctcaaccctt tgaacaatgc cataaatgtt ttcaacctta aatttttcaa gcggctcata
    36181 catctttaac gatagctctg gtcctgaaat gtgatcatag ccaggataat tttcaatatc
    36241 tgatgtgtta ttcatttgac cgccaggtgc cccctgctca ataatgccaa ctcgtaggtt
    36301 actacgtgct gcatataaag cagctgtcat accagcaggt cctgatccaa taatgagtgt
    36361 atcgtacatg ggttaactcc tcttaatagt cttgtcatca ttttaacaat agctacatcg
    36421 tattgcaatt atttcgcctt caataccacc agaatgctca taaaggcaaa ggacaaaatc
    36481 ggaatcgtca aaatagcaac cataatcatc tcatataaaa atgcctgtct ctggagaatg
    36541 gttttatcct ttttggtcac agcacgccat aaaatccaca aaagacaaag catgaccatc
    36601 gtaatagctg ctaacaacag accttccaaa taaaagcgaa aaatttctac taacatcttt
    36661 atctacctga ttaccataac cttttttcat ggcagcttag cttttaagca catacaagaa
    36721 aagcctagcc tacctagacc tttttattat atcaaaagcc ggcttttaaa tatacgtttt
    36781 tgcatagttt gcaaaaaatt cctttgttct tgcttcctta gggtgtctaa agatctgctc
    36841 aggagctccc tcttcaagaa ttttcccctt gtctaaaaaa agcaccctat ctgcaacctg
    36901 ataaacaaaa gccatatcat gactcactaa aatcatcgtt tgacctgcct tggcagcatc
    36961 aataatagac cgttcaacct ctccaaccag ctcaggatcc aaggctgagg taggctcatc
    37021 taataatagc acatctggct tcatggctaa agcacgcgca atagcaaccc tttgcttttg
    37081 accgccagat aaatgacgag ggtaatggtt ttcacgatca gacaagccaa ccttagctaa
    37141 ttctgctcta gctatgtctg ttgcttcttg gtcagacagt tttttaacta tttttaatcc
    37201 ttccttgaca ttgtcaagcg ctgtgcggcg ttcaaagagg ttaaattgct gaaagaccat
    37261 cgctaatttt cgtctaagcg ttagaatgtc ttcttttgtg atgtgttcaa agtcaactgc
    37321 aaagtcatca atcgtaatac ttcctgtatc tggctgttca agataattca tgcttctaag
    37381 gaaggttgat tttcctgcac ctgatgcacc aaccagagct ataacctgcc ctttttcaat
    37441 cgtcaccgtt aaatcgtcta agatcttttg tccagagaag gacttggtta aatgagttac
    37501 cttaatcatt agcgcaattc tcctatcttg ctattatttg ttgggattgg tgctttgata
    37561 gccatgttat attcaattag gcgaccagcc tgttctatca aaatactaat gccccaataa
    37621 actaaggcaa ctgagatgta acgttcaaaa taacgataat ctgctccccc tagaatctgt
    37681 gcctgtgcaa acatttcaac gatacctgca ttgaaggcca gagaggttcc ctttgtcagg
    37741 cctatcaacc cattaatcaa ggtcggtgtt gccacaacag cggcatttgg aatgataact
    37801 cggcgataaa cctgagcaga ggtcattcct aggctcttag cagcctcaat ttcgcctgtg
    37861 tgaacagatt gaatcgcagc tctaatggtt tcactcgtat aagcagcttc attgaaggca
    37921 aaggcggtaa tcgcaaagat agaagccgga atagcgttga tattccaatc aaagccatag
    37981 cgttgattta agaatttcag aaaaagagga ataccatagt agctcagcat tagctgaacc
    38041 aatatggggg ttccacgcaa aaagctaaca aaaaccgctt gaatcggata aagaatgcga
    38101 accctgttga ttttgacaat ggcaaaaacc aaggccaaaa aaagacccaa ggcagcacca
    38161 gctatcgtca aaccaagtgt gattggcaga cgcctgataa tatctggaat ggcatcaaaa
    38221 acagcatgcc agctaaacag cttcccttct gggatcaacg agatgagctt gtcataccaa
    38281 gcccacccac ttgttaaaaa cgtagatgtc atgtatcgcc cctttatact ggtttgtctc
    38341 aatattttca ttttaacatt cttgagatgt catgtaaaat agtaaatccg catgataatg
    38401 ataagaaaag cctatcgcag aggataggac tcaaacaaag gaaaaaaact ctttgaaata
    38461 ccgttaacag tagcctcttg gagctaccaa gcttgaactt gagccgaact ctcaaagcct
    38521 ccaagtggct aattctcaaa gaatatagcc actggtacaa gactaacaat cagctactag
    38581 gccaaaaagg tcaaaagctt ggctagctgg cacagctaac tgcctcaaag gctaggtcaa
    38641 cgaaagattg aagcctgccc agggcttgag ggcttttagc cctgtcaatt aattgacctt
    38701 ggagataaag tctcctccca aaaatgcttg gctgagcttt ctgagctgac ctgatttttt
    38761 aagcttagcc agccttttgt tgacaaagct ctgtagagcc ttaccctttt gatcattggc
    38821 aaacacataa tattccaagc catccttagc agtatcagcc tgctccttga gctttgtcac
    38881 atgcacatca aagccttgct cctcagctac ggttgttaga gaaatagcgt catagaaaag
    38941 aaagtccagt tgaccattct ccagcagctg cagcctttga gtaaatgggg ttgactcaga
    39001 agcataggta aggtgaatag gcttttggtc aggatgggat tggttccatt tttcaaggat
    39061 aagcatgtaa ttggagccag ctattccttg ggttttcttt ccagaaagat cagctaagct
    39121 tttatactgc tgcttaccct ttgttgccag agcataatgc gaggccgaaa tagggcttga
    39181 aaacaaatac ttttcagctc tttccttact atagccaaaa ttattggccc caatctgata
    39241 acgacctgca tcaataccag ccaggatcga tggaaaagga accacctcta tgcttaaccg
    39301 atactttttg gagcctttaa aaaccctttt tagaacctca atatcatagc ctgtaacgct
    39361 atgcttcttc ctataggtaa agggcttagt ggcagcatct gttgctactc tgatcacctc
    39421 tttttgacga gctgtgacct catggctagt cacgactgcc aagagtccta gacttgctag
    39481 caaaaaaaag agtgctcgct gtaattgttt tgtcatacca tactcctatc tcttatacag
    39541 tagccatttt aacaaaaaat gataaatttg aataatatca tttctctatc aaggcaataa
    39601 gaaaatagta tcaaacaagc aattaaaaca gcacattctt catttacctg atcatggatt
    39661 aaccacaaca gacaagcttt agctattagc aggctgccta agccaaaatc aacacctcaa
    39721 gctttcaact gactgatgta aaagctagta gtcacctcta caagaagaaa aagaactgtt
    39781 tgtgtcattc aaccagtagc acccttctta actggtcatt cctatccagc tctactacta
    39841 ggctgtcagt taacgatcag aaaaaaagtt gacctatctg ccttatgaag cctagaaaac
    39901 tagctttcat tctgtttaac attagaaaac gagtaaatag tttaaaataa atttttatta
    39961 ttaaacttta actgttgcta tattaatctt tttacattat aattaagtat aaggaggttt
    40021 tctatgaaaa aggcaatagt atcggttact ttgttaacag tagctgtttt aagcttatca
    40081 acaagattta tctactccac tgattattct gatttaaatc ataaggagat ggcacgtctt
    40141 atccagtcaa gaaaacaacc agtaattaag tatcatgaca atgtaaccat taataaaatg
    40201 attacttacc tagctcaggc taaaagagaa ggcattctga cagagacctt cctcatgaat
    40261 tatattttcg ctggagaggg tgagtacctg actaaaaatt caaggattat tgccgatcct
    40321 gacggagggt attggagtat cctagaaggt tatgagggag atggcggtgt taagactggt
    40381 attgacggcg tctcagagct caatatcttt agtccagaat ctaccagcat cggagagctt
    40441 caagaagcgg tgctagcctg gtatgaggct aataagtaac cgcagcttag ttaaccgact
    40501 gcttcatata atagctaata ttagctaatc ataggcctta taggcattga aatggtcaga
    40561 cccatgctca atgcttataa ggttttttag tgcttaccat ctaaccaaaa ccatagcctt
    40621 cagagagaca ttgagctgaa caagcaaaaa agaggagcaa gctcctcctc aaacattaat
    40681 acaccttaat ctacactccc acagaggaag taatttaagg ctggtgtgtc aaagcgtatc
    40741 aacccgttaa tttcaatcac tattctgaca gccaaaggtg cggctttagt tgttaatagc
    40801 tggttttagt tgccacgctt caaagatagt tgctgtaaca attgaagtag gttcgacaat
    40861 ttcaaatgta acaatacttt tatcacacct tttgcgggag cgtagattga aatccttgca
    40921 cgcaacgaca ggaccatttg acatgggaca ctgaacagag ttgaagcctt taaaaacaat
    40981 ccctaaacag ctttgggacc taatcacagt tccttgactc agctctgtca aggattctgt
    41041 tcatatcagc ttagaatgat cgctaaaaac tttttgatct aatttttctt gaacggatga
    41101 tctttaccaa gcacctgtct taaaagcttt gctttctgga ctgacgctct gctcgtccct
    41161 tggcacgttt ttctgctcgt cgctgcttgc gccgcttttc atcaactgcc cattgaattt
    41221 tctttttata gcccggttta atttttttct tttttttctt aaccaggcca atcatttcag
    41281 tgtctaattt ctgataagct ttttcacgat tctggcgacg atcacgatcg taagtatcct
    41341 gaaactcacc attttttaaa acctttggta taaaggtaat gcctagcttt tccagctcct
    41401 tgatatcaga atcatcactt ggctgataaa aggtaatggc tgtccctggc aggccgtttc
    41461 tacctgtccg ccccacacga tgcacaaaaa aggataggtc ttgaggaatg gcgtcgttaa
    41521 tcacatgact aaccccctca atatcaatac cacgcgccgc caaatccgtt gccacaatgt
    41581 attcaaatgc caggtttttg acttgattca tgatacgctt gcgctctcta ggaggaatac
    41641 ctccatgaag cttggctgcc ttcataccat tagctgctaa aaaggcatgt aagtcatcag
    41701 ctctctcctt ggtattgaca aaaagcatgg ccagataagg ctggatagcc tttagagtcg
    41761 ccaaaatttg ctcattttta tcgcgtccct tggttgataa cagccagttg tcaatcgtat
    41821 ctgcaataac ggtttctgtc ttgatctgtt caatgacagg attggtcaaa tacttcctta
    41881 aaaagggctg tagcttttgt ggaatggttg ctgaaaatac aagtatttgg atagtctttg
    41941 gcagtgctga agcaatctta tccacagtgc ttaaaaagcc catatccatt gtcatatcag
    42001 cctcatcaac aacaaaggta gaggccttat gaatggctaa atctcctgac ttgactagat
    42061 catagatacg acctggcgtt ccaatgacaa gctggggctg actaagcttt aacttgtcaa
    42121 gctgacgctg cttgtctgtc cctccaacgt aattagcaat acgaatctcc tgcttagaat
    42181 gcttagcaat ttgcctgctg gcctcaaaaa tctgtgttgc tagttcccgg ctaggtgctg
    42241 taatcacagc ttgaacctct tctttttcct ccttgagctt ttcaaaaata ggcagcaaaa
    42301 aggtatgcgt ctttcctgag cctgtctttg actcacccac taagtctcgt cctgtactga
    42361 caatcgggat aagacgctgc tgaacctctg ttggctctac aaagccaagc tcatctaggg
    42421 cctcttgaat ataatgctta aagtgataat cgtgaaatga cattatttac ctcgttttct
    42481 ttctgataat actattagtg cttgagatga gcaaaaggcg gtgcctcaag cactgcccca
    42541 gccgcttaca aataaagaat cgctaaaaca atgagactgg ctacaagacc aagagcccat
    42601 aggaaggcat caaccttcca ttcagaccac ttggctgctt taccggacaa gccgcctaat
    42661 tccagatgat gatgaaaagg agtcatccta aaaatccgac ggccttcacc atattttttc
    42721 ttggtgtatt taaagtaagt aacctgaagc atgactgagc ttgtctcaag aacatagaca
    42781 atcccaataa ccagcaaggt ccattcctga cgaagcgcaa tagaaatcgc tgctagcatt
    42841 gctcctaagg ctaagcttcc aacatcaccc ataaaaattt tggccggctt atggttaaac
    42901 aagaaaaagg ccagcaaggc accaaccatg atacctatca agagcaaaac atcaaattgt
    42961 ccctgagcat aagcgataac accataggcc agcaggctaa tcacaacaga taccgaggcc
    43021 agaccatcaa taccgtctgt caggttgacc gcatttgaaa agccaaccac ccaaaaaaga
    43081 acaaagcata ggtataaaaa gcccaaatgc caatgataac caaagacatt aatcgcatca
    43141 ataccacttg gcatgacgtg tatcacataa aagaccaggc ctccaacaat ctgaaacgtg
    43201 aatttttgct tggcagtaag gccttcatta acctgcttga agatctttaa gaaatcatct
    43261 aaaaagccta tgatcccgta aatcaataca atcaacaaga tccccgaaat caagcctagg
    43321 ctttgtccat ctcgaaaata gactaaagca aacacaaagg ataagcttgt agcaacaaga
    43381 agaaaaactg ttcctcccat tgtaggtgtt ccagccttag ccaaatgctg cttaacgtcc
    43441 tcatgcatct gctgcccccc aatttttttc aactggtaaa gccttataaa gtgaggcatg
    43501 gcaagggcag tcacagcaaa ggctatcaga cctgctagaa tggttaaaaa catgttaatc
    43561 tcctaaagtt atggtaattt ttttgacttt tttgagcgct tttccgacat caacgctctg
    43621 tttaacgaca cgtcccgagc ttgatccctt gtacttgata tcaatgccag tccatttagc
    43681 aaaggtagcc acattagcct tagtccagcc gtacatatca ggcatctcat caaaatgatt
    43741 tgataaaatc agaagctgtt ggttagcagc tagattggtc cctgcctttt tagatacctt
    43801 tttaatcttg ctgccattgc caaggacaat agggtgaacc agatttctgc gtagctcatc
    43861 agctgatttt cctgtatctt ggccaacaat atcaggcaac tgataagtag cctcgtgact
    43921 ggtatctaca gcaaccggct tgtctaaagt atccttcatc aaataggctt cctctaaaac
    43981 agggttgata atatcctgcc aaaacaccat tgcccaatgc tctgggtgct tcagtgtgac
    44041 atacatcaga aaatcaggct catcagctgg caccatagca accaccgaat aaatatagtt
    44101 tgtcaagcca ccatctaaat aacctgtacc gtccttagtc gcaatctgcg cagtccctga
    44161 cttgacagca actggtaatt gaccaacctt aaccactgga cctgatgatt tcaaatgaag
    44221 ggttccaaat tgtgggtcag tcccaacgtt aatcatgtat tttcgtgttt cactggcagc
    44281 cttttgggac accggctttc cgacaatctc cttgtctgac acccggtaag tatctgtatt
    44341 tgggtcataa atgcgactaa caaattgagg ctctagcatc acaccgtcat tagagatggc
    44401 tgtaaaggct ctaagcattt gaatttgcgt caccgaaatc ccctgaccaa aagcgctcat
    44461 tgcttgggta acaatattat cagaagggaa aatacctggg tcttcatttt ccaagccaaa
    44521 gcgtgtccgg aatccaaaac ggaatttagt taggtagttc atccatttgt catttcccat
    44581 tttttgctct agcttggtca tgccaacgtt acttgaaaac gaaaagcctt gagcataggt
    44641 catgtactgc cctgtagaaa tcccttcgtt aatcgcccaa tcctgaatgg tagcatcagc
    44701 aatggttaag ccattcgcat tgctaaaggt ctcatcagga ttaaagacct tctcatcaat
    44761 agcagctgcc agagtcataa ccttcatggt tgagccgggc tcaaactgcc cctgatggag
    44821 aatattttgc cagctatagc ttttgctgtt tagcccctcc aaggtgtctg cattataggt
    44881 tggtctttga gtagtcgcta agatttcacc agtcttagca tttactagag tagcactagc
    44941 aagctctcct tgcgccttcg actgaaagac gtccatttgc gtttctagaa aggtttgaat
    45001 aggctctgac agggtggtat aaacgtcctt accatcaact ggctttttca ctgtctttcc
    45061 tgttccaagc agggtattac cgtttctatc cttttgataa gtgatgattc catcttcccc
    45121 agataagatg ctatcaaagg ccgcctccat gcccatcttt ccaactaggc tcttggtacc
    45181 gtcctccttg ttttcctcaa gtgaagcaag accaatcagc tctgaagcaa aggtcccatt
    45241 tggatacata cggctaggac ttgctgaaaa tgcgatcccc ttgattttag ctgcctccat
    45301 agccttttgg atcgttgtca tcgtgctata agaaatacct gagccagacg gaccaaagga
    45361 aacctgaaaa agaccttttt gcttaagctg cttaataacg tccttttcct ccatacccag
    45421 ctgctccttg aggatttgag caaccttgtc atactgagac ggttgaacaa aaagcttctc
    45481 gccagtcgct gacacaaagg acttatcaag aatggcataa atgctatagg tcgtcgagtc
    45541 cacagcgata gctgtgccat tgcgatcata aatcgtgcct cgcttggcct gaacagaaac
    45601 cgtctcttga taaacctttt tggctccatc tgatagctta acaccgaatt tctgatccgt
    45661 cccgataatg atcataaaat taatcataaa gatgaagaaa ataaagatgg ttaagagcat
    45721 catgttttgc cccaccctca agcggttctg aacaggtgtc tttcgatcac gaaccacata
    45781 atctaaaaaa tatctttgcc attttgtcat agcttactcg accttcttaa tgttatcatt
    45841 tcggttacta agccctgctt tgccagcaat atcaacaatg cggtcacgtc gcgacagctc
    45901 attaacctct tgcttggcat tgttaagctc tgtcctttta tctgagatct gcctattgag
    45961 ctgagtgata tgctgctgga gctgcaattt acggctttgc aggtaaataa tgcttacagc
    46021 catcgttact gctgtcagga taagcgtagc ataaaaagcc ttctcaaccc tcgagaaagt
    46081 tctaattctt ttttgcaagg cttttgaaac tgcctgagtt cttttttcat taaccataat
    46141 ctatttccga acttttcttg cgactcgtag cttggctgaa tgtgccctat tgttagccat
    46201 tagctccttt tgacttggta aaatcggctt acgcgaaacc aattcaagct taggcttgag
    46261 ctcatcaggt ataaagggaa gtccctttgg agcatcagct gtgcttgctt ctttaaacaa
    46321 gtgctttgtc agacgatcct ccaaagaatg aaaggtaatc actgagatac ggccatcaag
    46381 ggctagcagc tctatcgccc gctggataga cgcatcagca gcaccaagct catcattgac
    46441 ctcaatacga atagcctgaa agatttgctt ggctgggtgt ccttttttct tgagctcctt
    46501 ggctggctta gctgatttga tcaatgctgc cagctctgtg gtggtgctga ttggcttaat
    46561 ggctctcgcc tgctcaatct tacgagcaat ctgctttgag aacttatcct caccatattt
    46621 aaaaaagatc cgaactaagt cattgaaatc ataggtattg acaacctcat aggctgtcaa
    46681 agccgcctgg ctatccattc gcatgtccaa gggagcgtcc tgcttgtaag aaaagccacg
    46741 ctctctctca tctaactgcg gactagaaac ccctaaatca tacaaaatcc catcaatctc
    46801 tgtaacccca tgctccagca agcgtgcctt aaggtgtcta aaattgtcct taataaaggt
    46861 cacctgtccc ttgtcaatat agggcttgag ctgctcctgc gcgtgatcaa tagccttttg
    46921 gtcctgatca aagcaataca agtgcccctt atcaccaagc agagacagca aataagctga
    46981 gtgcccagag ccaccaaggg tcgcatctac ataaatacca tctggcttaa tatccagcat
    47041 atcaacagct tcatgaagaa gtacagttac atgatgaaat tcgtttgtca tagctctaat
    47101 tgtaccatac ttcaaagggt ttataaatca aaaagtaaga gaaaagggct ttcaaggcct
    47161 aagaaagtcc ctctttatct tacttttttt ggcttagcta tccttgacat caagatgact
    47221 aagagcttgc tgcacagcct catacagcag ctcagccgat tcgagcacct gcttggtctc
    47281 ctttaacacc cgaaaatctg tcaccgaatt atctagccaa atatcaaaga tcttatcctg
    47341 tcttgtatga gataagctag aaggcaagcg caactcacta accttcagct ccttttgata
    47401 cctacagacc agatttctca cgtcccctag gctctcatta atagcactga ttttttgcct
    47461 ttttacccag cttgttagta tcccattgtc gaacaaatca aaaaatcccc acctcttaag
    47521 ctctttcaat gcctcaatga cagactcaag cttaaaagct aatgtcttta ggtctcgtat
    47581 ggtttcttgc ttctttagat cccttgtcat aagcctacct ccttagcagc tagctccgaa
    47641 tctggccatt tccattgatc aggtatttac tgctggtcaa ggcctcaagt cccatcgggc
    47701 cacgagcatg cattttttgt gtggaaatgc caatttctgc tcctagacca aagacaaagc
    47761 catctgtaaa gcgtgtcgag gcattcacat aaacagctgc cgagtcaacc agatcctgaa
    47821 aacgctctgc agcattgata ttagctgtga tgatggcttc tgaatgatga ctggtatact
    47881 gattaatcca agaaatagct tcatcaagag aggaaaccag atgaacagac atgatataat
    47941 ccaaaaattc agccgcataa tcttcctctg tggctaatac agccttgcta aacaaggctt
    48001 ttgcctgctc atctgctcgc cattccacct gctgaacctt gctgatggct gcttcaagca
    48061 tgggaataaa ggtcgctcct accttctcat gaataatcag gctttctgca gcattgcaga
    48121 cgcttggtct ttgcgtctta gcattaatca caaccttaac agccatctct agatcggctg
    48181 cttcatcaac ataaatgtga acattgccaa cccccgtctc aatgactggc accttagcct
    48241 tttccttgac cgtttgaatt aatctggcac ccccacgagg aatcaagaca tcaatataat
    48301 ccgttgcctg catcaattcc tcagctacag catgagaggt atcctcaacc agcaaaacag
    48361 catctggcgt aatagctgat gcctctaagg catttctgat aagcctgacc aaggccatat
    48421 tagagtagag agcatctttg ccacctctaa gaataatggc attattggtc ttaaaggcca
    48481 agctaaaggc gtcaacagaa acattagggc ggctttcaaa aatcatcgca ataacaccta
    48541 aaggcacacg cttttgggtt attttcaggc cgtccagatt tgtatagccc ttaatcactt
    48601 cgccaatggg atcagccaag tctgccacct gtctgacgcc ctgagccatc gcatggatac
    48661 gatctgctgt caggcgtaag cgatcgcaca gaatctctga aatcccatgc tcagccgcct
    48721 tagccagatc cttggcattt tctgtcaaaa tcatatccgt ctgggccact aattcctcag
    48781 ccaaaaaggc aagaaattga tttttatcct tcgttgtcaa ggataccaag gccctactag
    48841 ctgccttagc cctttgtcct agctgttcta ttgtcatcac gcgtcacctc tttctatctg
    48901 tttaaaccaa gtgcctagct tttctccctc caagaccctt aaaatgtctc tagggttggc
    48961 accattcatc aaaatcattt gcccctgatg ctcaaacatc atctgggctg attggatctt
    49021 acttagcata ccaccagttc caaatctgct gcctgcaccg cctgctgagg ctataatatc
    49081 ctctgtaatc tctgtcacat gactcctcaa gcgcgcgtcc tcatagatgg ttggattctt
    49141 atcaaacaaa ccatcaatgt ctgatagcat aatcagcaaa tcagcccttg taatacgagc
    49201 tacgatagct gataagcggt cattgtctcc aaattttgtt gaatgatcca tctcatcaac
    49261 actaacagca tcattttcgt tgacaatggg gacaatccct aaactaatca ggctttcaaa
    49321 ggcattggtg acatttgcca gactttctgg aaaaacaacc acatcacgtg tcagcaaaat
    49381 ctgagacact gtcgtctgat agtgggcaaa aatttgcgaa taaaggctca tcatagcaac
    49441 ctgccccaca cttgaaacag cctgctgctt ggcaagctga cttggtcttt tggccatttt
    49501 caacaggtca agcccaaagc ccatggcgcc agaggaaacc aaaataacct cttttccctt
    49561 attcattaag cttgaaatca caaaggctaa atggtcgatc ttttctaagt taatcttccc
    49621 attagcaagc accagcgagc tggttccaat tttaattaca atacgcttta catcttcaaa
    49681 ttgtcgtttc atcatattag gattatagca taaaaaacag cccagaggac tgttagattg
    49741 aagccaaaat caatcagcct atcagcttga taaaaaaaag gatcactggc tacccattca
    49801 cctaagatat aaaaatccac ctgatagcca ctccaagcag gatttccttt gtgacaccac
    49861 ataccacgct acgctttatc ctattgtaag tttaagtctg atcctcctgc attgtcctgt
    49921 catttttaat gaccatatac caacactaaa gctattgaca aaaacgcaca atacgataaa
    49981 atgaaagcgc aaacagctat atttactacc taagggccag accttgctgt aaagcgcaat
    50041 acctgacaga aagaacacgt ttcagaagta gcaagaacaa gtcacaggca tactgtctgg
    50101 cacattggcg caaaggctac cagtgttcaa caagactgga acgcaaatca ataggctgga
    50161 aatcaagtag gaaaaccgta tcatttaaat ttttggaatc ccaagactca attgttctca
    50221 attagtttgg gggcttagga cgacagagcc tgtcagtcat ctaaagcaat taattagtta
    50281 taggaataaa tcactatggt taaactatca aaaagaagca agatagctat gtcattttta
    50341 attgtctttt gtggtatatt tttcgtcgct caaaaacgat tcggttcatc agaccaatca
    50401 tttaccgtaa ggccagacgc agatttctat atagtcggtt accacaatat tgaaggttat
    50461 caattgacaa atgagcagcc gcaaaaaatt tctgacgcta agctcgaagt ggtcaaaggt
    50521 cagatcaatc aagtggttaa acgagcagag ctttcaaatc gttatctggt cttttccgag
    50581 gaggggccac ctttgggggc aataggaaga cttatcgctc ttgattttca aaaaggcaac
    50641 gtgacgtatc acccaacagc tgattatgcc tttacttcct ccggagtatc accagattat
    50701 tatttcactt ctacagcaa
//
LOCUS       DARYXZ010000010        49080 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYXZ010000010 DARYXZ010000000
VERSION     DARYXZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49080
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(185..655)
                     /locus_tag="TV186_000489"
                     /pseudo
     CDS             complement(185..655)
                     /locus_tag="TV186_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            870..1091
                     /locus_tag="TV186_000490"
     CDS             870..1091
                     /locus_tag="TV186_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1531916.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1121..1414
                     /locus_tag="TV186_000491"
     CDS             1121..1414
                     /locus_tag="TV186_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1531917.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            2551..4383
                     /gene="lepA"
                     /locus_tag="TV186_000492"
     CDS             2551..4383
                     /gene="lepA"
                     /locus_tag="TV186_000492"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL1531918.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            4925..5362
                     /gene="msrB"
                     /locus_tag="TV186_000493"
     CDS             4925..5362
                     /gene="msrB"
                     /locus_tag="TV186_000493"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1531919.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            5650..6669
                     /locus_tag="TV186_000494"
     CDS             5650..6669
                     /locus_tag="TV186_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL1531920.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            7013..7438
                     /locus_tag="TV186_000495"
     CDS             7013..7438
                     /locus_tag="TV186_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL1531921.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            7453..7944
                     /locus_tag="TV186_000496"
     CDS             7453..7944
                     /locus_tag="TV186_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1531922.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            7962..8771
                     /locus_tag="TV186_000497"
     CDS             7962..8771
                     /locus_tag="TV186_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1531923.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            8768..9595
                     /locus_tag="TV186_000498"
     CDS             8768..9595
                     /locus_tag="TV186_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1531924.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGIVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            9785..11419
                     /locus_tag="TV186_000499"
     CDS             9785..11419
                     /locus_tag="TV186_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1531925.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            11423..12208
                     /locus_tag="TV186_000500"
     CDS             11423..12208
                     /locus_tag="TV186_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1531926.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            12232..13242
                     /locus_tag="TV186_000501"
     CDS             12232..13242
                     /locus_tag="TV186_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1531927.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            13495..15279
                     /gene="uvrC"
                     /locus_tag="TV186_000502"
     CDS             13495..15279
                     /gene="uvrC"
                     /locus_tag="TV186_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL1531928.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            15407..16009
                     /locus_tag="TV186_000503"
     CDS             15407..16009
                     /locus_tag="TV186_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL1531929.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            16090..17499
                     /gene="pepV"
                     /locus_tag="TV186_000504"
     CDS             16090..17499
                     /gene="pepV"
                     /locus_tag="TV186_000504"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL1531930.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(17766..19142)
                     /gene="mnmE"
                     /locus_tag="TV186_000505"
     CDS             complement(17766..19142)
                     /gene="mnmE"
                     /locus_tag="TV186_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL1531931.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            19414..19635
                     /locus_tag="TV186_000506"
                     /pseudo
     CDS             19414..19635
                     /locus_tag="TV186_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
     gene            19758..20072
                     /locus_tag="TV186_000507"
     CDS             19758..20072
                     /locus_tag="TV186_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1531932.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            20077..20409
                     /locus_tag="TV186_000508"
     CDS             20077..20409
                     /locus_tag="TV186_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL1531933.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            20411..22009
                     /locus_tag="TV186_000509"
     CDS             20411..22009
                     /locus_tag="TV186_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531934.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            22003..22689
                     /locus_tag="TV186_000510"
     CDS             22003..22689
                     /locus_tag="TV186_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531935.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            22711..23397
                     /locus_tag="TV186_000511"
     CDS             22711..23397
                     /locus_tag="TV186_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531936.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            23419..24096
                     /locus_tag="TV186_000512"
     CDS             23419..24096
                     /locus_tag="TV186_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531937.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            24103..24417
                     /locus_tag="TV186_000513"
     CDS             24103..24417
                     /locus_tag="TV186_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1531938.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            24865..25548
                     /gene="rpiA"
                     /locus_tag="TV186_000514"
     CDS             24865..25548
                     /gene="rpiA"
                     /locus_tag="TV186_000514"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL1531939.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            25626..26837
                     /locus_tag="TV186_000515"
     CDS             25626..26837
                     /locus_tag="TV186_000515"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL1531940.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKSLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            27050..27859
                     /locus_tag="TV186_000516"
     CDS             27050..27859
                     /locus_tag="TV186_000516"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL1531941.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            27950..28735
                     /locus_tag="TV186_000517"
     CDS             27950..28735
                     /locus_tag="TV186_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL1531942.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(28868..29776)
                     /locus_tag="TV186_000518"
     CDS             complement(28868..29776)
                     /locus_tag="TV186_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1531943.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            30116..30565
                     /locus_tag="TV186_000519"
     CDS             30116..30565
                     /locus_tag="TV186_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531944.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            31186..31878
                     /gene="pyrF"
                     /locus_tag="TV186_000520"
     CDS             31186..31878
                     /gene="pyrF"
                     /locus_tag="TV186_000520"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL1531945.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            31938..32573
                     /locus_tag="TV186_000521"
     CDS             31938..32573
                     /locus_tag="TV186_000521"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL1531946.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            32625..33368
                     /locus_tag="TV186_000522"
     CDS             32625..33368
                     /locus_tag="TV186_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1531947.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            33603..35057
                     /locus_tag="TV186_000523"
     CDS             33603..35057
                     /locus_tag="TV186_000523"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL1531948.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            35177..36043
                     /locus_tag="TV186_000524"
     CDS             35177..36043
                     /locus_tag="TV186_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1531949.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            36071..36724
                     /locus_tag="TV186_000525"
     CDS             36071..36724
                     /locus_tag="TV186_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1531950.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            36855..37262
                     /locus_tag="TV186_000526"
     CDS             36855..37262
                     /locus_tag="TV186_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1531951.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            37274..37927
                     /locus_tag="TV186_000527"
     CDS             37274..37927
                     /locus_tag="TV186_000527"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL1531952.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            38159..39433
                     /locus_tag="TV186_000528"
     CDS             38159..39433
                     /locus_tag="TV186_000528"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL1531953.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(39487..40134)
                     /gene="plsY"
                     /locus_tag="TV186_000529"
     CDS             complement(39487..40134)
                     /gene="plsY"
                     /locus_tag="TV186_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL1531954.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            40267..42216
                     /gene="parE"
                     /locus_tag="TV186_000530"
     CDS             40267..42216
                     /gene="parE"
                     /locus_tag="TV186_000530"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL1531955.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            42318..43133
                     /locus_tag="TV186_000531"
     CDS             42318..43133
                     /locus_tag="TV186_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL1531956.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            43608..46067
                     /gene="parC"
                     /locus_tag="TV186_000532"
     CDS             43608..46067
                     /gene="parC"
                     /locus_tag="TV186_000532"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL1531957.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            46165..47190
                     /locus_tag="TV186_000533"
     CDS             46165..47190
                     /locus_tag="TV186_000533"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL1531958.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            47258..47488
                     /locus_tag="TV186_000534"
     CDS             47258..47488
                     /locus_tag="TV186_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL1531959.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            47549..47629
                     /locus_tag="TV186_000535"
     tRNA            47549..47629
                     /locus_tag="TV186_000535"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47583..47585,aa:Tyr,seq:gta)
     gene            47668..47739
                     /locus_tag="TV186_000536"
     tRNA            47668..47739
                     /locus_tag="TV186_000536"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47700..47702,aa:Gln,seq:ttg)
     gene            47867..49069
                     /gene="rpsA"
                     /locus_tag="TV186_000537"
     CDS             47867..49069
                     /gene="rpsA"
                     /locus_tag="TV186_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL1531960.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT        14120 a         9099 c        11458 g        14403 t
ORIGIN      
        1 gacttttgta ggcataattt cacctcgtga cgataccgtt acttcttttt gaccaagaaa
       61 agaaaatgaa agtaaaaata tgacgaataa tgttaatggt ataataagaa ttatcgcaaa
      121 attatgatag cgtcgctgat aaaattcagc acttctaaac agatttggat tcatgaatat
      181 ctccttactt actaaataaa tgatgataga agccttgatg cgtcattaat tcgttatgcg
      241 aacctatctc gattattttt cctttatcaa gtacaacaat ttggctagta cgttcagcag
      301 tactaagacg atgggcaacg aaaataatcg ttttctcggt cattgacatt aggttatcaa
      361 tcactttttt ctccgttaag acatctagtc cgcttgtcgc ctcatcgaga attagaatag
      421 gagacttggt taataatgct ctagctaatg caattctctg tttttgtcca ccagaaaatc
      481 ctgccccatc agatagttct gtctgatagc ccataggcat ttgttcaata tcttctctaa
      541 tttctgccat atcacaggca ttgataatat cctcttgagt aatcgcttgg tttgcaccga
      601 gagtaagatt ttctaaaatt gatccactaa aaatataagc ttgttgaggc agatattggt
      661 tatcgaaacg tcctaaatgg taatctgaca aatctatcaa attatctcaa acggttgaat
      721 ttaagtctta agcggtaaat ttttcccatt taggacgttt cgatgactgt ttaggaaatg
      781 gagaacaaat tttaaccgaa agtgttatac taagtctgtc aagcttgcaa ccggacaaaa
      841 taaaaacaca tataaaggag gtattcgtca tggatacaaa atttacagcg ttgactgaag
      901 agcaattgaa atcagttgag ggtggaaaaa atggagttgt aaaattacct ggagggaccg
      961 gtgtatattg ttggaataca ggaaaaaata gtgcaaaatg tggtatggac tggagtgtgg
     1021 caggaccata tgttggtaag ataattgtca atggttgggt taaccatgga ccttgggcaa
     1081 gtcgtccata attttaattt atatagagag gtgtgaaatc atgaatgaaa gagatttagt
     1141 acagctgata gaacagactc taaaagatga agaggtgcaa aataatgtca cttataggaa
     1201 tcttttggaa gaaagtctcc agcaattatc actcaaaaag cctgtgtatt tagttagtac
     1261 caggttagca ggacatattt caacctatct aatgacaaat cattatgagg caccaaaagc
     1321 gattatagtt cttgctcaat ctatcgcatc aaccccagct aaacatagag gtttaatttc
     1381 tataccattc tggttaagta atatatttcg ttaaaaaata ttttcagatc aggatttaga
     1441 aggagttgta gattggcaat gcactcataa aataagacac attttttgga gttttttgct
     1501 tgaactccta acttttacat tagtctataa acagtcaaag gaagttcttt caatctctca
     1561 aattgcaaaa caattttggc tatattttaa aagtacaatt ttgattccaa ttttagttac
     1621 aatcattctt ataaaggaga ttttgtcaag tacattacaa ataatgattt atttttacct
     1681 taatgttgtt gtcatgtgct acgctattgg aatgatctta tcgttaggtt atgtgatttc
     1741 acccaagcac tctatattca ataaaattaa aaatataaaa ttaaataata gagtatccca
     1801 agagattgcc gaatcccaat ttaccagtct tttagagcga agagcgactt gaagaaactg
     1861 ataaatttat ttggttttct gctaaaaatc ctgccaaaaa atctttggca ggatttttat
     1921 tttactaaga gatatttagg agtggctttg tcatttaatg cagattatga tatagcagga
     1981 gacatattgt tgaagctgtc tatgtcactt ttggtggcag gtaggtctta ttggaattgg
     2041 tgacttatga catttatcgg tggctgtaag cgtttgactt tttcacgttt catagtggtc
     2101 cgctctggaa tgagtgggta ttttttcaga atatgatcaa agatagatga catgttttac
     2161 agcaggctat agctggtatg atttgtttaa aaaatcaagg ccaatgataa gtgctgggtg
     2221 acataagtct tatggcttta cttcttgtta gcttgtgtca gcaggtgctg agtcaatcgt
     2281 tgtaggaatt atcgtaaacc taacagtagc tgctgttcta tttgtttatt ttctggtttc
     2341 tattcaaatt tctaaaatgc tagggtaaca aatatgaaac aagcaagtgg cgtactgcga
     2401 acagcttgat aacttattgc ctgcttaaag agggtgctgt tatgcttggt tttattaggc
     2461 ttatggcatg ggattaaaag gttgctgtag cgccattgtc attattttgg tacaataata
     2521 ggtaaaagac taaatgtata ggaaaataga atgaacagtc aagaattaaa aaaacgtcag
     2581 gagaacattc gtaatttctc tattattgcc cacattgatc atggtaagtc gactcttgct
     2641 gaccggattt tggaaaagac agaaacggtt tcaagtcgtg aaatgcaggc acagctcctt
     2701 gattcaatgg acttggagcg ggagcgtggg attaccatca agctaaatgc gattgagctg
     2761 aattataagg ctaagaatgg tcaagattat atttttcact tgattgatac accagggcat
     2821 gtggacttta cctatgaggt gtcccggtca ctagctgcct gtgagggtgc tgttttagtg
     2881 gtggatgctg ctcaggggat tgaggcacag accctagcaa atgtctatct ggcgcttgat
     2941 aatgatttgg aaattcttcc agtgatcaac aagatcgatt tgccagcagc tgatcctgag
     3001 cgggttcgtc aggaaattga ggacgtgatt ggtctagatg cttcggaggc tgtacttgcc
     3061 tctgcaaagt ctgggattgg tattgaagat attttagagc aaattgttga aaaggttccc
     3121 gcaccgtctg gtgatgttga tcaaccgctg caggccttga tttttgattc ggtttatgat
     3181 gcttatcgtg gggttatcct gcaggtgcgt gttgtcaatg gtatggtcaa gccaggtgat
     3241 acgatccaaa tgatgtcaaa tggaaaaacc tttgatgtga ctgaggtggg gatttttacc
     3301 cctaaggcta ttggtaggga ttttcttgct actggtgatg ttggctatat tgcggcctca
     3361 atcaagacag ttgctgatac gcgtgtcggt gatacggtca ctctggctac aaatcctgca
     3421 gcagagccct tgcatggcta caagcagatg aatccaatgg tgtttgcagg gatttacccg
     3481 attgagtcta acaaatacaa tgatcttcgt gaggccttag aaaagcttca gcttaatgac
     3541 gctagcttac agtttgagcc tgaaacctcg caagcattgg gctttggttt tcgttgtggc
     3601 tttcttgggc tgttgcacat ggatgtcatt caagagcgtt tggagcgtga attcaacatt
     3661 gatttgatca tgacagctcc gtctgttgtc tatcatgtta atataactga tggtgacatg
     3721 cttgaggtct ctaacccgtc agaatttcct gatccaacta aggtagatag tattgaggag
     3781 ccttatgtca aagcccagat catggtgccg caggagtttg ttggtgctgt tatggagttg
     3841 gcccagcgta agcgtggaga ttttgtgacg atggattata ttgatgacaa tcgtgtcaat
     3901 gtgatttacc atattccctt agctgaaatt gtgtttgact tctttgataa gctgaaatca
     3961 tcaacgcgag gctatgctag ctttgactat gaaattgctg aataccgtcg ctcgcagctg
     4021 gtgaaaatgg atattttgtt gaatggtgat aaggttgacg ctcttagctt tattgttcat
     4081 agagcatttg cctatgagcg cggtaagctg attgttgaga aattaaagaa aattattcct
     4141 cgtcagcaat ttgaggtgcc gattcaagcg gctattggtc aaaagattgt ggctcgctct
     4201 gatatcaagg ccttacgcaa aaacgttctt gctaaatgct atggtggcga tgtttcccgt
     4261 aagcgtaagt tgcttgaaaa gcaaaaggct ggtaagaagc gtatgaaggc tattggctct
     4321 gttgaggtgc cgcaggaggc cttcttgagc gtcctatcaa tggacgatga gagtaagaaa
     4381 tagtgacatg ttaagtaagg agctggatca tgcgatctgg ctcttatgct tgatgtctcg
     4441 ataggctaga aaatagggct tgtgtcatga taggcttgta tgtttgagat ggtttggaac
     4501 ataatgactc tatcatatct gtagtggatt gacaaagagc cgtaaaccat tgatatttgg
     4561 atagttaatt tcgagttatt ctgtagtact ctcttaaggt ctttcatatg agcttttcta
     4621 atgttggttt ggttgctttt catgataagt catatgggat ttttttggta tactgaaaaa
     4681 agcctatagc ctctacagtg gcgtctccct ctacagagat gatagagcca gagtgattgt
     4741 tacgatctgg agatgtggcg ctaggcatta atgcaggagg acttaaccag attgctgtta
     4801 ggcttgaaat cttaagctat attgattgtc agcttgattt agagaagtct aagtttatgg
     4861 ctcacaaatg ctcggtcttt ttgttacaat agagttaatc agttattttt ataaggagac
     4921 agctatggaa tctaaggaag agcttcgcca gcgtattgga gatttggctt ttgaggtgac
     4981 tcagcatgca gcgaccgaaa gagcctttac aggtcagtat gatgattttt ttgagaaggg
     5041 gatttatgtt gatgtggtga gcggagaggt gctcttttcc tctttggata aattcaattc
     5101 tggctgcggc tggcctgcat tttctaagcc gattcagcat cgtatggtaa ccaatcacca
     5161 tgattcatca catggcatgc ggcgtgttga ggttaaaagc cgcgaggctg gctcccattt
     5221 ggggcatgtt tttaatgatg gccctaagga ggcaggaggc ttacgctatt gcattaactc
     5281 cgccgcgctg aaatttatcc cctatgatca aatggagcaa gagggctacg ccgaatggtt
     5341 agggattttt gataagagct aggaattgct agcggccaat gaaaaggtag agctcttagc
     5401 caatgctagt ggctaaatca aagaaataaa aaggtggcta aagtacatag aaaaaagagg
     5461 taagcagatt ggcaggtggt caatctgctt tttgtgagga gactttcagc ctgctttgcg
     5521 ctaaaaagta tgaaaccaat aaaccaccta ctatgcgggt gtgtgtcggt ggttagctta
     5581 agttttttca gttcggtttt acaagcttct ctaaaaggac tataatagct aatggaaaag
     5641 gagattcata tgctaacatc tttagaaaaa ttaccgggcg ttttactgtg cttgctgtta
     5701 gcactgcctg cctggtattt gggaagctta tttcctatta ttggagcgcc agtttttgct
     5761 attttattgg gaatgctatt ggcgcttgtc tatcagaagc gtgactacac taaatctgga
     5821 atcgcattga cgtccaaata tattttgcag ctggctgtgg ttttcttggg ctttggctta
     5881 aacgtgacac aggttttagt ggttggcttg caatccctgc cgattattgt agtaacgatt
     5941 gtgactgcct tgggcataag ctatttgttc aaaagatggt taaggctacc agccaagaca
     6001 gctatcttag ttggtgtggg ctcgtctatt tgtggtggct ctgctattgc agccacagct
     6061 cctgtcattg atgcgcagga cgatgacatt gccaaggcca tttcggttat ttttttgttt
     6121 aatatcttgg cggccttgct atttccagct ttgggtcaga tgcttggctt atcaaatcat
     6181 ggctttgcta tttttgctgg aacagcagtc aatgatacct catctgtaac agctacagcg
     6241 acagcctggg acgctattca ccagtctaat acgctagatg gggcaaccat tgtcaaatta
     6301 accagaacgc tggctattat tcccataaca cttggcttat ctatttacca aaccaagagc
     6361 aggcaggcac atacgacaga gggttccttt agcctcagaa aggcttttcc gacctttatt
     6421 gtctttttct tgctagcttc cttgataacc acctttgctg ctagcttagg tctgccaatg
     6481 gcaatctttc atcagcttaa gctactctca aaattcttta tcgttatggc catggcagcg
     6541 atcggactta ataccaatct agtgacctta gtcaaaactg gtggtaaggc cattttgctg
     6601 ggtgggattt gctggctagc gatcacatca gttagcttag caatgcaggc agctttgggg
     6661 agctggtaac tgatgagaat agctggtgat acgctgcttt ataggaaaag caaagccctt
     6721 gctgctccta aaaaagcttg ttagagcagc tcacttagct gttaagtgtg gcttggtggg
     6781 gtgtaagtag gctctatcag ttagaaaagc catcagaaca aacgctatca ttaagctgaa
     6841 gccggggaaa ctcggctttt acgttatgca gaattgtcta catattgaat aggattatcc
     6901 attttaaaaa cgttttcatt tgatagaata caattatagc ttggttatta gggtaaacga
     6961 gattgaactt cttatctggt ttagcttaag taaaaaagca gttggaggaa gcatgaaacg
     7021 taaattttta attggtagtc atgggagaat ggccagtgga ttgaaaagct ctattgacat
     7081 tttggctggt agaggtcagg aattacaagt cattgacgct tatattgatg atagtgatta
     7141 tactgagcag gtattgacct ttatcgaaga tgtagcagct gacgagcagg cactgatttt
     7201 tacagattta ttaggtggca gtgttaatca aaaaatagta actgccctaa tggacagtgg
     7261 caaggaaaat atctttttga tttcaaatag taatcttgca gccttgctat cgttgatgtt
     7321 tttaaagcca gaagaagagc tgacaaaaga cgagattgta gcaacgatta acgattctca
     7381 ggtgcagctg gtggatctag ctccagcgac agccgcagaa gatgactttt ttaattgagg
     7441 aggaaaaatg aaatgattac acaaattcgt gttgacgaca gattgattca tggacaggtt
     7501 gctgttgttt ggaccaagga gcttaatgcc cctttgcttg tggtggctaa cgatgaggct
     7561 gctaaaaatg agattacaca aatgactcta aaaatggcag ttcctaatgg catgaaatta
     7621 ttgattcgct ctgttgagga ctctatcaag gttttcaatg atccacgcgc agtggataag
     7681 cgtatttttg tcattgtcag ctcgattaag gatgcttgcc agattgcaaa gcaggtgaag
     7741 gacttagagg ctgttaacgt tgcaaatgta gggcgctttg acaagtcaga cccagcaact
     7801 aaggtcaaat tggcttcaag cctattgtta aatccggctg aattagaagc agcaaaagag
     7861 ctggttagcc tgcctaacct agatgttttc aatcaggtac tgccatctaa tagcaaggtt
     7921 agcctgagcc agctcatcaa ataaagaaag gtgtaatgac tatgttagta ccagcaacaa
     7981 tggcagcctt agctgtattg atttgtttcg ggggaaatta tttaactggc caaagcatga
     8041 tggaaagacc gcttgtggtt ggtttggtga caggattgct cttaggagat atgaaggtcg
     8101 gtatcttgat gggagcgtca ctagaggcac ttttcctagg aaatgttaac attggtggtg
     8161 tcattgcagc agagcctgta acagcaacag ctatggcaac gacctttacc atcatttcac
     8221 atattgatca aaaagcagct atgacgctag ctgttccgat tggcatgcta gcagcctttg
     8281 tggtcatgtt tttgaaaaat gtttttatga atatctttgc gccaatggtt gataaggcag
     8341 cagcggcaaa ccatcagggc aagcttgtca tgctgcacta tggcacatgg attgtctatt
     8401 atttgattat tgcctctatt tcctttatcg gtatcctagt tggaagcgga cctgttaacg
     8461 cctttgttga gcatattcca caaaatctga tgaatgggct aagtgcagct ggtggtcttc
     8521 ttccagcagt cggatttgcc atgctgatga agctcttatg gacaaataag ctagcagttt
     8581 tcttcctatt aggctttgtg ttgacagctt atttgaagct accagcagta gctgtggctg
     8641 cacttggtgc agttatctgt gtgatcagct cgcagcgtga tttagagtta gatgctatta
     8701 ctaagggagc tatcagtaac caaagcagct ttgactctaa agaatcagaa gaggaggact
     8761 tctttgcatg agatctcaag acaatttaac taaagaagaa agaaaaatgc tacgctctgt
     8821 tttctggcgt tcatggacca tgaatgctag tcgtacagga gctacgcaat accacgctgt
     8881 tggggttatc tataccttgt tgcctgttat caatctcttt tataagacag ataaggataa
     8941 ggcagacgct cttgttcgtc acaccacttg gtttaatgcg accatgcata ttaataactt
     9001 tatcatgggc ttggttgcct caatggaaaa gaaaaacagt gaggatccaa cctttgacgc
     9061 tagtgctatt acagcggtca aggcttcctt gatgggacct atttctggtg ttggagattc
     9121 ctttttctgg ggtattttga gggtcattgc agctggtatt gggatttcac ttgctagcac
     9181 aggctcagcg atgggagcag tagtcttttt acttctctat aatattcctg cttttatcat
     9241 tcattattat agcctttatg gtggctattc tgttggtgct ggctttatta aaaagcttta
     9301 tgagtctggt ggtattaaga ttgtgaccaa gacctcaagc atgcttgggt caatgatggt
     9361 tggctccatg acagcttcaa atgtgaagtt taagaccatt ttaacagttg ctgcaaaggg
     9421 agccaaggaa gcagcctcta tccaaaatta tttggatcag ctctttattg gaattgtccc
     9481 tcttttagta accatgaccg ccttttggct tttgcgtaag aaggtgaaca ttaactggat
     9541 tatgtttggc attatgctat tgggtattgt tcttggtctt ttaggtattt gctaataatc
     9601 tcctagcatc aaggataggt aaggcaggga cttcttgctt tgcttatcct tttttgtagt
     9661 gagggctgct gaaatagcca cctgcttgct taaatggctt atggatttgt tagatagatt
     9721 aagattttct tagctttgag aaatgatttg gtataataga aggaaataag ggaaaaggct
     9781 gcctatggaa gaaagattta aaaagcgatt gcaggatgat atttcacatc atttttcaca
     9841 ccaatcattg attttgtcca ttttactgat tggactcttt ctcatttttt cattggcacc
     9901 tcagcaaatt gggctgtatc aagatttgaa ggctgttgaa catagctatc accagctgat
     9961 tcggcaaaat aaggcgcttt taacggagct caatcagcat attctgacca aatttgtgaa
    10021 tcatcagctg agctcttctg accttagcaa acaatattat cacctaagaa accgctcaca
    10081 aagccaatca gagctgctgg tttttgatgc taacagtcac atgctgtttg ctagtaatca
    10141 gcatctggga aatttttttc gcaatgctgt ctatatgaca gaagtcttaa aaaaagcaag
    10201 gcaaaggagt agcttcttga ggatcagtat ggataatgag gaggggcatt atttactgct
    10261 gataaagcct attaagatag atcatcaggt taagggctat tcgcttcttg tgatgaatgg
    10321 taaggatttt cttcagctat cacatcagat tgcttcagat tttgtgattg cagatcagtt
    10381 tgacaatagc tttgccttta ccaatcggac ctttatgacc tcaagtctga ataagcttga
    10441 cagtcatttt cttaagggct attttatctt tcacgagcat cgtgccttta tcctaagaaa
    10501 ggtcgctctt agtccttcta tcactcttta cagctaccgc cctttgattc cagtttctat
    10561 tgcactcttg ttttcattga tgtcctctgt catgatttat gctattttgt attggaagtc
    10621 taaggctctg gcgacgcaga ttgcttctag caattcagca gcgatcaatc agatgattct
    10681 tgatatgcag gccatctcaa ggcaggaaaa aaatgccatt gacctgcaaa gtcaagatga
    10741 atttcaatac ctgtcggttc agatcaatca gatgattagc cgattgcagg cacttcatca
    10801 gaagacccta gccttagaaa agcaaaatgt gagttttgaa aaacgcatgc tggaagccca
    10861 atttaaccct cattttctct ataatacact tgaaacaatt ttgattacaa gtcattatga
    10921 cagtgacctc acagaaaaaa ttgtccttca gctaaccagg ctgcttcgct atagcttaga
    10981 cgaatcacag gaggctgtgt gtctgggaga ggatttggct gtcttagaat cctatctgtt
    11041 gattagccag attaggtttg aagagctgcg ctacacgata gctgttgaac cagccctaga
    11101 gaccctaagg gttcccaaat tatttttatt gccattgatt gaaaatgcga tcaaatatgg
    11161 tctgcgctat cgccatgacc ttgtgattga gatcagcgtg agacagcttg ctgatggaat
    11221 ttactttact gtagcagata acggtcctgg aattagtcaa aaaaggcagg ccgatattaa
    11281 agagctcttg cattcagagg attcacatca tggcttggtc aattcttatc gtcgactcaa
    11341 gcatcaattt ataaaagttg aattgatctt ttgtcaaaga gatgagcgct ttttactaac
    11401 ctatatggtt aaggagtaac agatgtataa gctactaatt gttgaagatg agcatattat
    11461 tcgcaaatgg cttcgttatg cgattgatta tcatgcgctc aatatccttg ttatcggaga
    11521 agctaaggac ggtcagcagg gggctaagct gattgcagag gctaagccag atattgtttt
    11581 gacagacatt aacatgccga ttatgactgc ctttgagatg tttgaggcca caaaagagca
    11641 gtcctatgct aaaatcattt tgtctggcta tgctgatttc gctaatgcaa agtctgctat
    11701 ccattatggt gtgcttgagt ttttgaccaa gcccttggaa aggcaggcct tacatgattg
    11761 cttgctaact attatccaaa agctgcaaca gcagtctcaa gagcaggagc taagccagca
    11821 gcaggattac ctcaaactgc cacagcctaa tgaccaattg cctgatgttg tccaagaaat
    11881 gctcagctgg atccatgagc attaccagga taaaatcatg attggtcagt tggctcacga
    11941 tctgggctat agcgaaagtc acctctatca tttagctaaa aaatacctga aaatgacttt
    12001 tagtgactat atcaaccaat accgcctgaa tcgagcaatt caattgctga ttgctgagcc
    12061 ggatgtgatg gtttatcagc ttgcagaggc tgttggcatt tatgactacc gctattttga
    12121 tcgtgtgttc aaaaaatatt taggacaaac ggtcaaggat ttcagagaaa cggtattaca
    12181 ccagagatca gataggagtt cattgtgaca agaaaaaagc tgctattagc aatggcaata
    12241 gtgatactag gtgtgattgg ctctggcttg tatgctatct ggaggcatca agcaggacca
    12301 gctcccagca aaccaagaga attggttgtt ttgacaccca acagtcaaaa tatcctaaca
    12361 ggtacgatcc cagcctttga agaaaaatac ggcattaaaa tccgtctgat tcaaggaggc
    12421 acaggccagc tcattgatcg cttgcaaaag gacaaggacc agctccatgc agacatcttt
    12481 tttgggggga attacacaca atttgagagt cataaggagc tatttgagcc ttacctttca
    12541 aagcatattg gctttgtatt gcctgattac ctgctgcaaa gcgaggtcgc aaccccctat
    12601 acgcttaatg gaagtgttct cattgtgaat aatgaattgg caaaggacat ggttattacc
    12661 agctatgagg atttgctaaa gccagagcta aagggaaaga ttgcttttgc agaccccaac
    12721 acctcctcta gtgccttttc tcagctgacc aatattctct tagccaaggg gggctacact
    12781 aaccccaagg cttggagcta tatcaagcag ttgattcata gcatgaattc aatcaaatct
    12841 gctagctcat cagatgttta tcagtcagta gcagaaggaa agatgaccgt cggtcttacc
    12901 tatgaggacc cctgtgttaa ccttttaaag agtggtgcca acgtttctat tgtgtatcca
    12961 aaggagggaa cggttttttt accctcagca gttgccattg ttaagcaatc taaggccaag
    13021 gctgatgcca aattgtttat taattatatg ttgtctttag atgtgcagcg ggcctttggt
    13081 caatcaacca gtaataggcc aattcgaaag gacgctaagg ccagtcaaga catgaagcct
    13141 ttagatgaca ttatcacgct aaaggaagac tatgattata tcacaagaca taaaaaggat
    13201 attttagaac gatacaatca attgagaaag accactgact aaatggcttt gttatatgaa
    13261 acagttcatg ctgtgctgca cctgaatcgt tagctgcttt gtctagcttt ttgaggtcaa
    13321 tctctgcttg ggctgttttt tatgttacca taacccactg catttgttta gaaagtcaag
    13381 cgagatctta atagccagtt ataataggtc tttgagaggg agtctgagct tgcttgaggt
    13441 ggcaagaaga tctgttttga cgtcaaatgg ctgaattttt ggtaaaatga tagcatgaat
    13501 gaactgataa aacacaagct agagcttttg ccagatagtc ctggctgtta tttgcataag
    13561 gataaggctg gcactattat ttatgttggc aaggccaaaa atctgagaaa tcgcgtacgc
    13621 tcttattttc gaggaagcca tgataccaag acagagctgt tagtttctga aatagctgat
    13681 tttgagttta ttgtcacagg atcaaataca gaagcactct tattggaaat caatttgatt
    13741 caagagaaca tgcccaagta caatatcaag ctaaaggacg acaagtctta tccctttatc
    13801 aagatcacta acgagccatt tccaagacta ttaatcacac gtcagattaa aaaaaatgac
    13861 ggcctgtatt ttggtcccta cccagatgct tacactgcca ctgaggttaa aaagctgcta
    13921 gaccgtattt ttccctttaa aaaatgcaaa aaccctgtta acaaggtctg cttttactat
    13981 catttagggc aatgtcaggc tcacacgatt tgccatacag acaaggctta ttgggacagc
    14041 ttggttgctg atgtcaagca gtttttaaac ggtaaggacg acaagatcat tgatgatttg
    14101 cgctccaaga tgcttgaagc ttcgcacaat caagaatttg aacgggcagc tgaatatcgt
    14161 gatttgattt caggtattgc caccatgcga accaagcaaa gggtgatgag taaggacttg
    14221 caggataggg atatttttgg ctattttgtt gataagggct ggatgtgtgt gcaggtcttt
    14281 tttgtccgtc agggtaagct cattcagcga gatgtgaata tgtttcctta ttacaacgaa
    14341 gctgaagagg attttttgac ctatgtcggg caattttata gcgaccaacg gcatttgatc
    14401 cctaaggagg tctttattcc agagacgatt gatgagacct tggttgcagc cattgttcca
    14461 gcaaggattg tcaagccgca gcgaggggaa aaaaagcagc tggtcgcctt agcaactaag
    14521 aatgctcggg ttagccttca gcaaaaattt gatttgctgg aaaaggattt aagaaaaaca
    14581 agtggtgcta ttgagcatct tggtcagctg ttaggcattg aaaagcctgt tcgtattgag
    14641 gcctttgaca attcaaacat tcagggcaca agtccggtag ctgcgatggt ggtttttgtc
    14701 gatgggaagc ccagcaagaa ggactatcgc aaatttaaaa tcaaaacagt gattggtcca
    14761 gatgattatg cgagcatgag agaggtgatt tatcgtcgtt atagccgcgt gaagcatgaa
    14821 gggctacagg cacctgattt gattattgtt gatggtgggc agggtcaggt caaggctgct
    14881 cgtgatgtga ttgagcacca gctaggcctt agcattccag tagctggtct gcaaaaaaat
    14941 gacaagcacc agacccatga attgcttttt ggtaacccct tggcagtggt tgagctgccg
    15001 agaaattcag aagagttttt tctgctgcat cgtatacaag atgaggttca tcgctttgcc
    15061 attacctttc acaggcaggt caggagtaaa aatgcctttt catcaaagct agatcacatt
    15121 gcaggcttag ggccaaaacg caaacagcta ctactcaagc gatttaaaag catgactgct
    15181 cttgaacagg ctagtcttga agaaattcag cagctaggga ttccaaaaac agtcgctgag
    15241 gcactgtttg atcaccttac ctcaaaaagt gaggtctgaa ttggccttgt caggagctca
    15301 agcagtctga attttcttga caaaagtgaa aaaatagctg aaaccagttt caaaaaatga
    15361 tagaatgata ctacaacata aaagaattag ataggaagca tttgcagtga aatttctcga
    15421 attaaacaaa aaacgccatg ctattaaacg gtttaacgat aagcccgttg attataatga
    15481 cttgcgaaca gctattgagg ttgccactct ggcaccaagt gctaacaata ttcagccttg
    15541 gaaatttgtc attgttgagg aaaaaaaggc agagctggca aaggatctgc cgttggctaa
    15601 taagactcag gtagagcagg ctcagtatgt tattgccctg ttttctgata ccgacctcat
    15661 tcagcgctct cgtaagattg cccgcattgg ggtcaagtcc ttgcctgata acttgattgg
    15721 ttattacatg gagaccctgc cgccacgttt tgctaccttt actgagaccc aaaaaggcga
    15781 atatctggcc attaatgctg gcttggtggc gatgaatttg gtccttgcct taacggatca
    15841 gaaaatggcc tcaaatatta ttttaggctt taataaaaag ctaactaatg agattttaga
    15901 tattgatcca cgctttcgtc ctgaattatt gataactgtg gggtatagcg atgacaagcc
    15961 agagcctagc tatcgcctac cagtagacga aatcattgaa agacgctaag atacacaact
    16021 actcgtccag ctagcctata agtttttgga tttaggagga tagcgaggca acacataaag
    16081 gagaaaaaga tgacaacaat tgattttaaa gcagaggttg ataagcgcaa ggaagctatg
    16141 ctagaggatc tatcaaacct attaagcatt aattccgagc gagacgatgc taaggcagat
    16201 gccaagcacc catttggtcc tggtccggtt aaggccttgg agttctttct tgccatggca
    16261 gagcgtgatg gttaccaaac gcgtaatatt gataactatg ctggtgattt tgaatttggt
    16321 cagggagatg aggttttagg gatttttgcc catttagacg tggtacctgc tggtagtggc
    16381 tgggagacag acccttataa gccggtgatt aaggataatc gtatctatgc gcgtggttca
    16441 tctgatgata aggggccaac catggcttgc tattatgccc tgaaaatcat caaggaatta
    16501 ggcttgccag tttctaaaag ggttcgcttc attgttggga ctgatgagga gtcaggctgg
    16561 ggtgatatgg actattattt tgctcacaat ggcttgaaga accctgattt tggtttttca
    16621 ccagatgctg aatttcccat tatcaatggt gagaaaggaa acattacaga ataccttcat
    16681 tttgttggtc aaaatgctgg agcttttgtc cttcatcgct tccaaggcgg tttacgtgaa
    16741 aatatggttc ctgaatcagc gacagctctg atcagctcac cgcatgagct taatgttatc
    16801 gaagcttctt tggagcaatt cttatctgag cacgcagtga caggatctgt caaagaggct
    16861 gatgggctat tggaagtgac cattattggg aaatctgctc atggctctac accagaggct
    16921 ggtgttaacg gtgcaaccct gctggctaaa ttcttaaatc aatttagctt tgatggcgca
    16981 gccaaggctt atttgcatat tgcaggtgag gtgcttcatg aggatttcac agcagaaaag
    17041 cttggcttgg cttatacaga tgacaaaatg ggtgccctta gcatgaatgc aggtgtcttt
    17101 agctttgcta aggattcaga tgacaatacc attgccttga atttccgtta tccaaaggga
    17161 accaatgcag cagtgctaaa ggcagggctt gagcaattac caggcttgac taaggttacc
    17221 ttatctgagc atgaacacac ccctcactat gtgccaatgg acgatgagct ggtctcaacc
    17281 ctcctatccg tctatgaaaa gcaaacagga ctcaagggct acgagcaggt tatcggtggt
    17341 ggcacctttg gacgcttgct tgagcgtggt gttgcctttg gtgcgatgtt cccaggtgat
    17401 gaaaacacaa tgcatcaggc caatgaatac atgccattag acaatattta ccgatcagct
    17461 gccatttacg ccgaagctat ttatgaattg atcaaataag agattgaaca agctctctgt
    17521 ctaagatgag ccttgctaat attaacgaat aaaagcctta tgaagttagt cgtttaatga
    17581 gacttcataa ggctttttgt ttggcgtcaa gccattattt acaaagagaa atgccacagt
    17641 ggatcatctt ttgaaaagtc cttgtaaaaa cagacgtaaa actagtttta gaggagacat
    17701 tgataggcag tcatgcttat caagagatct tgtctagcag ttatggcaaa aagatcagtg
    17761 aactattatt ttccaaggca gaactgactg aacaattgag taattaattc atcaggtgcg
    17821 gcatcgcctg tgatttctcc taggatttcc caagctctgg tcaaatcaat ctgtaagaga
    17881 tcaaccggca ttcctaaagc aagtccttca ttgacagcct ctaagctttg tactgcctgc
    17941 tcaatcaagg aaatatgacg agcattggat aggtaagtcg catcttgctc tattagccca
    18001 gtatgatcaa agaaaatctg attgatccgg tcttcgatca ggtcaatgtt ttggttttgc
    18061 aaaactgata ttgggatcgc ctcttctgga agctggtctt tttcaatgac ctgctccaga
    18121 tcggttttat tgaggagaat aatgcgattg ctatcctgac taagggctag cagagccttg
    18181 tcctgttcgg tcagcttttc cgaagcattg agaactaaaa ggaccagatc agcctcctgt
    18241 agggcttttt tagaccgctc aacaccaatt tgctctacta aatcatctgt ttctctaatt
    18301 ccagcagtat caactagctt tagaggaatt cccttgatat tgacatattc ttcaatgaca
    18361 tcacgagttg ttcctgcaat atcagtgaca atggccttat cctcacgtaa caaggtattg
    18421 agcagactag actttcctac attcggtcgg ccgataatag ctgttgacaa gccctcacgt
    18481 aggatcttcc cgcgcttggc agtacgtagg agctgctcta aaagtgtttg aaattctcgc
    18541 gttttgtcac gcaaaagagc agtggtcatt tcttcgacat catcatattc ggggtagtcg
    18601 atattaacct caacctgggc taaggtattt aggatttctt gacgtgtgtc gctgatgagc
    18661 tgtgataggg agccgtctag ctgcttgata gcaatagaca tggccttatc agtctttgca
    18721 cgaatcagat ccatgactgc ctcagcctgt gttaaatcaa tacggccatt taaaaaagca
    18781 cgctttgtaa attcgccggg ctctgccatt cgagctccct gtttaatgag gagctgtaaa
    18841 atgtcatttg tcaccgcaat accgccatgg gtattgattt caatcacgtc ctctctggta
    18901 aaggtttttg gcgccagcat gactgatacc atgacctcat caatcacttc acctgtgctt
    18961 ggcttgataa tatgaccata gttaagggta tgtgaggcga ctgttgttag atcttttcct
    19021 ttaaagatcg atttagcaat gtccagagcc ttggtaccag acaagcgaac aatgccaata
    19081 gctccttcac ctaacggagt tgaaatggct gcaattgtat caaattcttt agttatactc
    19141 atgccttcta ttgtagaaca agtcagcata gaaagcaagg tattgcatta gctgctcgtt
    19201 gtcgtcattc ttgtctagtg gcaaagcctc aaaagcagtt gtaaacagct aaagctatga
    19261 ttaaaaagcc ttgtatggta agtacaggat aaagccaaaa agctgatgag ttttagataa
    19321 acatacaggc tcgaaaagcc ctattaaacc gacagcaaca atcctcacac agtatagttg
    19381 acttaactac ctgatgtcat ttctggctgt ttttataatg acaatggcaa tatcggttat
    19441 tttgactatg ctgggtgctt gtatcctagt ggactgactg acaatcaggg cttctttttc
    19501 aaccacgaaa acattaaaaa agtctggttt ggaggctata ttgacgatag tgaaagagaa
    19561 gctcaagact tttttaaaaa agaggcaggc tatattaaat atcctaaact tagtatagat
    19621 aatagcacta gatagcatta atttaagtat ataacgttat gattatggtt ggattagttc
    19681 attatacact agcaataagg tagattattt tgttataata aaatatatac aattattaga
    19741 gagttagaaa gagttatatg gtagtattac aaaataatag tagcacagct agtgagcgag
    19801 cgacagcttt ggcaagagga gtccaggccc tctctagtgc tggtgcggtg agcaaagata
    19861 tgaagacgac cgttactgga aatcgtagtg atgccagctc tgccattgat ttatcgcaca
    19921 acgtttcagc gcaggtagtt gggatcatcg cttctatgtc gcaacacatt cagagtgtct
    19981 ctgcctcttt tcaagcgatg gatcttcagc ttggaaaaga gttagggcgt ttagaaaaca
    20041 ggcggaggtt tagtctcaat gacccaaaat gagctcatgt accagaagga gagattggat
    20101 aaacgcttgg aaaccatagc ccaagagctt aagcgtaatg aacagcgctt tgaagactat
    20161 gaggaactat ctaacctagc ggcacaactg ttaacagcag ctgcaaccac ctttcgttca
    20221 tcatcagata gtcatctctt tgaaggggct ttggcagaag aatgttattt gaaaaggaaa
    20281 acacaagcgt ccttggaaca aagtcatgag gagctcttag gagagcagcg tcgtttgtac
    20341 caagaagagg aagccctcac ccgacaatta aagctagtca aaggaaagga gagagctaat
    20401 gagcattgac atgtatctgg ggtcatcgga ccagcaagct agtagcgttg gtaaggtctt
    20461 gcagcagcgg ataacagctt ataagtcttt gcaaagagct ttggagcaat tggtgtcttc
    20521 tagtcctgac ttatcagggc atacctatgc ttctgctaaa aggtacagcg agcaggtatt
    20581 gatccctttg atgaggggct gtatcctgct agatgaagcc atcaaggaag cctgtgcagc
    20641 atttcctaat gactaccgtc gtcaggttga tagtgtggat ttgaaggaga gtgagctggt
    20701 ggatcagatc agccgctcag accgcatcat aggtcgttac gttgagttga ttgatctgga
    20761 gtatcggcag gagctgccga attactctta tattactaat ctcaagagcg gagcgagtaa
    20821 ccagcgtcaa gtcaagagaa aattagaaga gaagctcctt aagctgcgag agtttgatag
    20881 caattcccgt cacctctttt cgtctatcgc agccttagcc gaggcagtca atataggtat
    20941 cagacaaacc aagacctctt ggaatgggac aagtcagacg ttcactcttc ccagggctct
    21001 tgacttagag tggaccaagg tagtagaaaa gaggtggacg caaagggagg aaaaagcctc
    21061 gaagctgaag ctacagcagg cagcagaaaa actttcgaga gaaaccggga ttaagtacga
    21121 agatgcctat cgttttgtga tggacggtgt tctgtcagat gaaaataaga acaaaatcaa
    21181 gagtgtaaag aaactagtta agtatacaaa gggtgggctg tatatcgttt cctcaggaag
    21241 gtattattgg aaacattcag gtaaacatta ttggaaaaat acaccaaaca aaacatggaa
    21301 tatttggaaa gcatctaaaa acgatcccaa ttttgacaaa ggagggatca aaggtaaaca
    21361 tttttctaaa aaaggagccc gttacacaga cttacctggt atcaagcaat tgaagaagag
    21421 tgaaacagta caatccctca tttcaaaaat ttcaaaagat aatcaaggga agctcaccaa
    21481 agttggtaaa gggttaaaga aagttgataa agagctaagc aacatatcgt caaaactcaa
    21541 gtcatatgag catggacgcc taaatagaga cttgaaaatg atgaaggaga ataacctggg
    21601 taaaagtctc ggtaagtttg ggaaagttgg aaaagctgca agcaaggtgc tcaagtttgc
    21661 aggaaaaggt ctcaaagttg cgggttgggt aggtgctgct ataaatgtta aggactcggt
    21721 tgaaacttac aagaaaaaag gctatagcaa tgagcaaact gctgctttaa cagcccgtaa
    21781 ggtagctgtt gatactgcaa caactgttgt cggaagcaat attgggcgtg taacaggtgc
    21841 agttattggt caagcagtta tacctattcc aggtgtaggt gctgctatcg gttctgttgc
    21901 aggaagtatt ttaggagcta tggcaggtag ttggattggt agtacaatta atgacaattt
    21961 agataagaac gtaaaaccta aacaatcagg aaggagttta gcatggtaat gttaatgaga
    22021 acactgttat ttccagttga taacggactt gattcaggat tgactggtga tggttatgca
    22081 gctgagtatg atttgtggac tggaaaggtc acgtggcgac aacttggtga tggaaaaata
    22141 aaaaggcaac aaaaggtagc agctataatt aatctcattg cagctgcaat atctccactt
    22201 gtcatcatgt ctatcatttt tacggcaaaa agtctgaagc tttttgatgt agatactagt
    22261 acaacaattt atcgatatgc tcctctgatg gtaggcttgg tctttttctt ctcgtttgaa
    22321 ttattgatgc tggctattag acgtctgtat ccattagcca aagaggagcc aagtttaaag
    22381 cgtcaacatg ggtattttaa gaccatgtat gacaatacta tacgtgagaa tgatggtgtt
    22441 tttaataatt tatcagtacc ttttataggg ctttatgtag ctttcttgat tgccttttcg
    22501 gttattccaa ttttttactc tcaatatctg cagcaaaatt ctttttggtc ctatttagga
    22561 aatttagtag gaagtagcat tcttatttcc ttagtcccca attttttatg gaatgtctta
    22621 gtgaaacaat tgatttacat caagcttatt cgcaaaacga aagaaaaaat cttaaagaat
    22681 gaaacctaaa caatcaggaa ggagtttagc atggtaatgt taatgagaac cttgttattt
    22741 cccatagata atggtatgga taataactta attggagacg gcttatcagc tgagtatgac
    22801 ctatggactg gaaaagttac gtggcgtcag cccagtgatg ataagattag aacccaacaa
    22861 aaggtagcat ttgtacttaa tcttatagct ggtagtttat ctccattagc tatattttta
    22921 tttgttatta ttgttagacg cttaggcgtt tttagtggcg atactaattc aatgattttc
    22981 aagtgggcac cgctaatagt tggatttatc ctttttatat cgtttgaatt attgatgttg
    23041 gcgcttagaa gtagatatac gatattagag aaagagcccg atttagatcg tcaactatac
    23101 tattatcgta caatgtatga taatactata catgacaatt caggtgtttt taacaattta
    23161 tcagtacctt atgtaggtct atacattact ttatttctaa tttttttaat cattccactt
    23221 tgttatcatt tttacttgca cccatcttca tttggggatt atctcgctgc attatctgta
    23281 acaagtttgt tgatttcctt atttcccaat tttttatgga atggtgtctt gaagcacgtt
    23341 atatatgtca aacttattcg ccaaacaaaa gaaagaattt taaagaatga aacctaaaca
    23401 atcaggaagg agcttagcat ggtaatgtta atgagaacgc tgttattccc agttgataat
    23461 ggcatgggaa cgggcttgac cggtgatggt tatgcggctg agtatgatct atggactgga
    23521 aaggtcacgt ggcgacaagc caccaaacaa acaattgaaa agcaacaagc actaacgtct
    23581 aaccttttga ttattgcctc atgcttatca ccagttactg ttgcaggaat gatactgttg
    23641 agtagaagtt tccctatttt cgaggaagac ttatcagaga aaattgatac ttatgctcca
    23701 attattcttg gtgttgtgtt atttcttgct tttgagacgt taatgcttgc tatcagaggt
    23761 cgtgatccat tagcggagaa ggaaccagat ttaaagcggc agcatgacta ttttgaaaag
    23821 atgtttgatt ttgctattcg tagaaatttg tcgtcagata atctaaaaac tccttatata
    23881 gctacttatt ttgcttttgg tatttcttta ctctgtattc catttagcta ttatgtttat
    23941 ctgaatccgg agcaattccc taatttggat tatggtcatt tatcaatcct gcttgtaaca
    24001 agtattctta tttccctagt tcccaacttt ttatggaatg ttctattaaa gcacattatc
    24061 tatatcaagc ttattcgcaa aacgaaagga caataaaaca ttatgaacaa accagaacac
    24121 attttaccga ttggtactat agtgctgacg gagacaggag aaattccttt gatgattgtg
    24181 agtcgtgcct ctctttttga tgataatgga gaaatcggct attttgatta tgctgcagtt
    24241 ccttatccag aaggcatagg aaatgataat gagtaccttt tcttcaacca tgaggatatt
    24301 gctgatgtca tctattttgg gtatgtcaat tccaatgaac agctttttgc agaagcctac
    24361 gatgatttgg tgaaaacatc aggttatcgt aaattaagct tagatcacca tcaatagaaa
    24421 aaggacatga agattatcta gaaaaagaaa agaactaatg agcattgaca tgtatctggg
    24481 gtcatcgaac cagcaggcta atgatgtatg gccaatattt tgagaggatc ggcctgctcc
    24541 tcttttttgt atgttcaaag ctataaaaag cttacttttt gaggtataaa gcttcgacaa
    24601 tcaagagtat ttgctctggt ggctttaatg atcttgctta tagcttctgg tcagattgtt
    24661 ttagcctgct tgtgctgtct gatccagatt tgactgaggc tttgatgaca gtcgtgaagg
    24721 cgggtttaag aatggcatgt ctaatgtcaa tttacaatag agaaggaaaa ttgatcaaac
    24781 agtgtgagat attattaaca agtttgcgct ttcatggtat aataaagtgc taggaagcat
    24841 tttattataa gataaggggg aatcatggaa gcactgaaaa agattgccgg tgtgactgct
    24901 gcgcaatatg taacagatgg aatgaccatt ggattaggaa caggatcaac agcttattac
    24961 tttgttgaag aaattggtcg tcgcatcaag gaagagggac tacaggttgt tggtgtgaca
    25021 acctcaagtg taacaaccaa gcaagcagag ggcctaggta ttcccttaac atcaattgat
    25081 gatattgact gcattgacct gactgttgat ggtgctgatg aggtggataa ggcctttaac
    25141 ggtattaagg gtggtggagc agctctattg atggagaaaa ttgttgcaac accaaccaag
    25201 gaatacatct gggttgttga tgaatcaaag ctggtggatc atttaggtgc tttcaagctc
    25261 cctgttgagg tcgttcaata cggtgctgat aggctatttc gagtctttga aagggctggc
    25321 tataagccct cttttcgcat gaagggggat aagcgtctca taacggatat gcagaacttt
    25381 atcattgatc ttaaccttgg ctgtatcgaa aatccttgtg agtttgggcg tctgctggat
    25441 caaactgttg gtgttgtcga gcatggcctt ttcaatggta tggttgataa ggtcattgtt
    25501 gctggtcagg ctggtgtaac ggtccttgaa gctaatcagt caacctaatt cctagctcaa
    25561 tcatgtttta cattatttta taggttttgg ggagccaacc gtaacctccc ctagattgga
    25621 gacttatgtc aaaatttaat cgtattcact tagtcgttct agattctgtt ggtattggtg
    25681 cagcaccaga tgccgacaaa ttctttaatg ctggtgtagc tgatacagat tctgacaccc
    25741 tcggtcatat ttcagagaca gctggtctgg ctgttccaaa tatggcaaaa attggacttg
    25801 gtcatattcc tcgtcctgtc cccctaaaga cagttccagc tgaggctgat cctactggct
    25861 atgtcaccaa attagaagag gtatctcttg gtaaggatac catgacaggt cactgggaaa
    25921 ttatgggctt aaacattact gagccatttg ataccttctg ggatggcttt ccagaggaga
    25981 ttatccaaaa aatcgaagct ttttcaggcc gtaaggtcat tcgtgaagcc aataagcctt
    26041 actcagggac aaaggtgatt gatgattttg gtccccgtca aatggaaact ggtgagctga
    26101 ttgtttatac ctctgccgac cctgtattgc aaattgcagc acatgaggag gtgattcctg
    26161 ttgaggagct ttaccggatt tgtgagtatg cgcgttccat tacccttgag cgtcctgctc
    26221 ttttaggtcg tattattgcc cgtccgtata taggagagcc aggcagcttc actcgcacag
    26281 ctaatcgtcg tgattatgca gtctcaccgt tccaagacac tgtcttaaat aagctggctg
    26341 acgctgggat ttctacttat gctgttggga aaatcaatga catctttaat ggctcaggga
    26401 ttaccaacga tatggggcac aataagtcta acagtcatgg gattgatacc ctgatcaaaa
    26461 gcttgcagtt gccagcattt acaaaaggtc tttcttttac taacttggtt gattttgatg
    26521 ctagctttgg tcaccgtcgt gatccagagg gctatcgtga ctgtttgcat gaatttgatc
    26581 gtcgcctgcc agagatcatt gccaacatga aggacgatga tctgctcttg attacagctg
    26641 atcatggcaa tgacccaacc tatgctggaa ctgaccacac acgtgagtat attccattgc
    26701 ttgcttactc agcctcctgc actggagcag gtgtgattcc acagggacat tttgctgata
    26761 tttcagcgac tattgccgaa aacttcggtg tggacactgc tatgattgga acatcattct
    26821 tagctgactt ggtataggag taagcaaata tcatttgata ggccaaggag cttggcgtat
    26881 caaattgaaa accagcgctg tggttaggtc tattaatagg cttgtggcag gttgtctagt
    26941 tctgatgatc ggtgtgatat tagttgattt attggacttt gctacagcaa aaagctcaag
    27001 agaagtatgc tttatagtaa aaaataaata agataaaggg agaaataaga tgacattact
    27061 tgaaaaaatt cgtgaaacac aggctttcct agaaagcaag ggcattgata agcctgaatt
    27121 tggtctcatt ttaggctctg gtctaggtga gcttgccaat gaggttgagc aggcgattgt
    27181 gattgattat gctgatattc caaactgggg caaatcaaca gttgttggtc atgctggaaa
    27241 attagtttat ggtgagctgg ctggtcgtaa agtattggca cttcaagggc gctttcattt
    27301 ctatgaaggt aatccaatgg aggttgtgac cttcccggta cgtgtgatga aggctctggg
    27361 ctgccatagc ttgctggtga caaatgcagc aggcggtatc ggctatggtc ctgggacgct
    27421 tatgctaatc aatgaccata ttaatatgac aggaacaaac ccgctcattg gtgaaaacct
    27481 agatgaattt ggcccacgct tcccagatat gtctgatgcc tatacagcag cttatcgtga
    27541 gacagctcgc tcagtagcag aaaaactagg cttagacctg caagagggtg tttaccttgg
    27601 ctgttcagga ccaacctatg aaacaccagc tgagattcgt gcctttaagg ttatgggagc
    27661 agatgctgtt ggtatgtcaa ctgttccaga ggttattatc gctgcccact caggcttgaa
    27721 ggtgcttgga atttcagcga ttacaaactt tgcagcgggc ttccaatcag agcttaacca
    27781 tgaagaggtt gtagaggtaa ctgagcgtat caaggaaaac tttaaaggct tggttaaggc
    27841 tattttggca gagctttaag gcttgctctt agactagcag taaccatgag cgactgctag
    27901 tactttgatc gataagacga ggaaaaataa ggattgggac attagagtga tgactgatat
    27961 ggaacatacg ataagtattc ttttagaagt ttatgcttat agtcatgcct acaaaattgc
    28021 aagaactctg cctgattttt cccccaaggt actttatttg cttgagcttt taaaggaaag
    28081 aagagagctt aacgttgctt atgcctttca acatagggcg gaaaataggc ttattgagga
    28141 tagacatcag gttaagcttt tgttaaatga agctcaagag gaggagcaga ctgcaaatta
    28201 cctgcttgat ttggcagcta aggtcaaaaa cggtgagatt attgattttg taaggtcagt
    28261 atcgcctgtc ttgtatcgtc tctttttgcg gctgcttgag caggctgtcc cagatgttca
    28321 aagctatatt attgatacca agaatgatca atatgacact tggaatttta aggcgatgga
    28381 aaaagccgat aatgacctct ttaggagcta tctggcacaa agacagccac gtcatgtgac
    28441 gacacgcagc ttggctgatt tacttgtttt atcagagctt ccagctgata ttaaaagact
    28501 agtggtagtc ttaaggcagt ttgaaaaatc agtccgcaat cccctagcac atttgatcaa
    28561 accctttgat gaggaggagc tatatcggac aactcatttt tcctctcaag cctttctaga
    28621 tggtttgatt cgcttagcag ttttttctgg tgttaactat atcaaagagc ccttctattt
    28681 tgatgtcgtt aatgctgtca ttgaaaagga gctgttagac agcgccaagc cttagctatt
    28741 tgaaagatta gcaataataa aaaacctgaa cgatctgaac gaggcttctc taagctagct
    28801 atgactagtc agcttagagc cttagaacag gtctttcagg ttttttatgt ttagctagtg
    28861 tggttaatta atgattgaag ctaatttctt ctagcaggta gtcaataaat cgctctccca
    28921 tttttgagag gttagccttt tcgtgcttga taaagacaat ctcaatcaca tcagggacat
    28981 ctaagggaat agcgacaatc tggtctccat ttagatttgt gtttaaaata ccgctggcaa
    29041 cggtgtagcc atttaagcca atcatgagat taaatagggt agctcggtca ctcaccacaa
    29101 tagacttact gtgagggata tgtgccatca tctcctctga gaaataaaag gaattgtgaa
    29161 tcccctgatc atagcttaga taaggaaaat caaggagatc atcaatggtt aagctggttt
    29221 tatttgccag aggattggac ttgctgataa agatatgcgg tgtggtttta aatagggtgg
    29281 aaacggtcaa atgattttcc tcaaacagct tggtaaggac gtctcggttg tagtcattga
    29341 taaacaaaac gccgatttct gagcgaaaat ttttcacatc gtcaatgatt tcccaggttc
    29401 ttgtttctcg caagaaaagc tcgtactggg tcatatcagc ccgctttaat aaagagacaa
    29461 aagcattgac aacaaaggcg taatgctgag aggaaacact aaagagctca cgactagtat
    29521 tgtgattttt atagcgatcc tctagcagtg ctgtttgttc aataatttgt ctggcataag
    29581 atagaaactc aaccccgtcc ttggttaagg taatgccctt gggattacga atgaaaatag
    29641 taatgcccat ctcctgctct aattccttga cagcattaga cagactgggc tgcgtgataa
    29701 ataattgctt agcggcttcg ttcatggaac cgcattcaac aatctttata atgtattgta
    29761 gttgttggat tctcatactg acagtctatc ttaaatagta caaagaatca agtgccttta
    29821 ttagagctta agacaaggtt tcacaagcgg tagcctagct tgtgcggtga agctagcttg
    29881 atgctagtgt tgtacccagg taaaaaagag ctggcaaata ggcagtttta tcgcttttta
    29941 ccgcttattt ttggcatgcc tgtgttttga taaacggctg gtcttgatcg gtaaaaagta
    30001 atcgtgataa tgtcagataa tacctatttt tccattgctc ttttaatttt cttgtgttat
    30061 attaataata ttgatatatt taatgttttg agataaaggg tggtgatggt gtaatatgac
    30121 tggacaaagt agtcatcagg tattaattca aaagctgttg gtcagcactc actatttgac
    30181 attatttaga gatgagctga agctagttga gaggacacca tctattttgg gaagtgagtt
    30241 tcctgtctct cttgttcaaa cggaattagg tgatattatc accttggtgg ataccttaaa
    30301 taagcagcag cgcttgattg agtcgacctt ttggtatgag gagtcagcct ttaagctcat
    30361 gaacaaggcc ttagatattg ttgataattg gataaagggg atagatggct taattaagct
    30421 ctgccagtcc aaggaggtct ttcaggccat tgttggtgat aaaagaacac gtgtttttgg
    30481 tgttttgatt gatgtttttt cttccctaaa aattagcacc atgtcattga aggaatttgc
    30541 agctccggct gctctttgcc attagattaa gctgggctaa gcttggatag tggctggtta
    30601 agcctgcaag ttgcccctct catgacaagt ctaggcttta tttagggtga gcagtgtgcc
    30661 aagggtgtat taagtgctgg ttgctttgaa gcttcgcctt gctaggttag ctgtgagtga
    30721 tgtcacgata actgcgcgaa acagttattt ctgaattata atacaggtta aagtaggtac
    30781 ttttaatgtt tttcctattg taaaatctat acaaaatagg atatattttt gaaatagctg
    30841 aacattaacg tacagcaagc tttattttct tgctaaaaat cttttttata cctttgtcgt
    30901 gtgagtaatg tcaaaaccct ttgacaaggg ctgtcaaaaa agctataatg attgagataa
    30961 gttaccttta agtgagtcca gagaggcgag caaggtacac aggataagat gagagggttt
    31021 gctctcttga ttttcgtgta gcctcgcttc tttggaagtg aggcttttat ggtgtgactt
    31081 tcagttggtc tcgtggtaat gattcataag accaataaac cgctcgttag acgggtgggc
    31141 atgatttgtt tgggagtacc ccaagctgca tagaaaggat aggttatgcg agaagaacgc
    31201 cctattattg ccttagattt tccttccttt gaggaggtca agtcatttct gtcgctgttt
    31261 ccagctgatg agaggctata cgttaagatt ggtatggaac tgtattatgc tgaaggacca
    31321 gatattgtcc gttatgtcaa gtccttaggt cacagtgttt ttctggattt gaagctgcat
    31381 gatattccaa atacagtcaa atcaacgatg gcagtcctat caaggcttgg tatagacatg
    31441 acgactgtgc aggctgctgg aggtgtagag atgcttagag cagcgcgtga gggcttgggg
    31501 cagggtccga ttctcattgc ggtgacacag ctaacatcaa ctagcgaaga gcaaatgcgt
    31561 gaggatcaaa acattcaatc cacgctgtta gcatctgtgc ttcactatgc caagcgtacc
    31621 gctcaggcta agctagatgg cgtggtttgc tcagcccatg aggtcaaggc cattaagtca
    31681 gaagtaccag caggctttgt gtgtttgaca cctgggattc gcccgacagg tgctgacatc
    31741 ggagatcaaa agcgggtgat gacacctcat caagctagag ctatcggaag tgactatatt
    31801 gttcttggtc gtccgatcac tcaggctaca gaccctgtca aggcttatca ccagattaag
    31861 gcagagtgga accgttagca gcaggatcat catgacacat atagctggac tatgacacca
    31921 aggaaaagag gagaaaaatg acactagcag cacaaattgc aacagattta cttgagatta
    31981 aggccgttta cctaagacca aaggagccct ttacttgggc gtcaggcatt acatcaccga
    32041 tttatacgga caatcggatc accctttctt atccaaaaac cagaagcttg attgaaaatg
    32101 gctttgtgga gacgattaag gcagtatttc cagaggttga ggtgattgct ggcacagcaa
    32161 ctgctggtat tccacatggt gctatcgttg cagataagat ggacctgcct tttgcctata
    32221 tccgcagcaa gccaaaggat catggagcag gcaaccaaat agaagggcat gtgcgctgcg
    32281 ggcaaaaaat ggtgattatc gaggatttga tttcaacagg tggatcagtt ctggaggcgg
    32341 cagcggcagc tagtcgcgaa ggtgctgatg tactaggagt ggtggcaatt tttacctatg
    32401 aattgccagt agcaagcatc aattttgaaa aggcagggct ttccttggtg accttgtcta
    32461 attattcaga cctcattaag gtcgctaagg ccaagggcta tattgatgct gatggcttgg
    32521 ccctgttaaa aagatttaag gaggatcaaa agcattggca gcatgagagt taaacagtgc
    32581 tgaaaagctg ctgacatgct gactatgtct taaggagaga aaaaatgact tacaaagatt
    32641 tacttgagat aggtgagacc agttattatc agacggatcg cttgacttac tacaaaaatc
    32701 ctgtggtatc tgagcgctat tttgataatt accttagcta tcgtagcatg ccttctttgg
    32761 ctgatttgaa aaaggacttg gcctatgtgg caaaagagca gcaggattat cctagtcact
    32821 acgcctttct cttttttgct gaaaatgaag agctaagtac agacatgcga gcttatttga
    32881 cagatcatca ctttagcctt gaaaagcacc tgatctttac caatgagctg gcaaagcttc
    32941 acctaaagga gcgtgatata tcaccagtca ctattgaaca gctctcagaa acaagctttt
    33001 ctgcctatct ggcttacaaa tatcaggcta atttggctta tggtgaaacc tatgccaatc
    33061 aatgcaaggc tgataatgaa gccaatctat tgacaaacgg ctcaaccatt tatttagcca
    33121 tcaaggaagg gaagattatc ggagatatta cggcttggga atgtggcgac tatattgaaa
    33181 tggacgattt cagtgtagat gaggcctatc gtggtcgtgg tatcggtaca gccttacagc
    33241 gtaaggccag tcaaggctat aagaaggtca ttctcatctc agaagaagct aatcgcgcca
    33301 tgtatgagca ccaaggctat caggaggttg cttactactg gacagcgcta aaaacatcga
    33361 ctagataagt gataaagaaa cagattatag gattgaaggt gtaggctctt atgagtatga
    33421 ctcttcaatc ctttttttct gagcgcattt gctaatcata cctaatgaat aagtcgtagc
    33481 ctgtctagtg gctcatttta atggcgtctt gctctgtttt atgattaaat atagagaaaa
    33541 agctattgtt agggcatgct tgttggtcta gcaaggctga tggatgatag gatagggaat
    33601 tgatgatttt taaagatgca acagaaatgg cgcaggctgt tcgagaaggt agggtgagcc
    33661 cctcagcctt agtgagagac acaattaaaa aggctcaagc actcaatcct gagttgaatg
    33721 ctattacctc agagcgtttt tcagaagctc ttgctgaggc agcagcaagg gatttttctg
    33781 gaaagccatt tgctggtgtg cctatttttc taaaggattt agggcaggag caggagggcc
    33841 aattggccac tgcaggatca gtgttattta aggattatcg tgcctcaaaa acggattatg
    33901 ttgtgcagcg actagaggag ctgggcttta ttattttagg aagaagcaat acacctgaat
    33961 ttggctttaa aaatattagt gatagtcgct tacatggtcc ggtaaatctg ccacaggaca
    34021 agagccgtaa tgctggtggt tcatcaggtg gggcagcagc tcttgtgtcc tcaggaatca
    34081 ccttgctggc tcctgctagt gacggaggag gatccattcg gattcctgcc tcctttaatg
    34141 gcttgatcgg tttaaagcca agcagaggaa gagtgcctgt ggggccaggc tcttatcgtg
    34201 gctggcaggg ggcgtctgtt cattttgctc taacgaggtc tattcgagac acaagtcgtc
    34261 ttctttatca cttgcaggtt tatcaggtag aaagcccttt tccattagtg ccattaacca
    34321 aagaagagct ttttcaccct ttagacagac ccttaaggat tgctctttat gatcacatga
    34381 tagatggaac taccgcctct atagatgctc agacagcttt aaccgaggcc tgtcattttc
    34441 taaaagagat ggggcatgag gttgtgcgat tagataagct tcctctagat ataccaaagg
    34501 ttatgaggga ttactacctg atgactagtg ttgagacagc tgctatgttt gctgatagcc
    34561 aagaagccct tggtcgtcag gtgaccaaag cagatatgga ggtcatgacc tgggctatct
    34621 accaagcggg taaggatatt cttgcttcgg tctattctca ggcgctgcag cgctgggacc
    34681 attatagtgc tgaaatggca agctttcatg agcagtatga tcttttgctg acctttaccg
    34741 ccaatacgcc tgctccaaag catggacagt tccagccaag caaggagcta atagataagc
    34801 tggctaaggc ggaatgctac ccctccagtc agcgcctagc gctagtagaa gccatgtttg
    34861 agcagagctt gttcataacc ccttacacag ctttggcaaa tctgacaggc caaccagctc
    34921 ttagtttacc aacctatgaa acgtctgctg gattgccgat gggcattcaa ttgatagctg
    34981 ctaaagggcg agaagactta ttgctgggaa tagctagaca gtttgaacgg gctggattgt
    35041 taaagctacc tggttaaata ttataaaaca gagctaatct attataggtt agcttttttg
    35101 ttaaatcgag catatctagt ctcttataag attagtcaat gctatactgt cattaataat
    35161 gaaaaaggag ttcttgatga aaaaaggagt tgctttactt tctgttagct tggcgagctt
    35221 gctgttagcc gcctgtgggt cacagccatc agctcaaaaa acaagctggg aaaagattaa
    35281 agataaaggt gttttaaagg ttgctacgcc tgcgacctac cagccaacat cgtactataa
    35341 tgatgccaat gaattggtcg gctatgaggt tgacctgatg aaggaaattg ggaaacgcct
    35401 tgatcttaag gtgaagttca ttgaaacagg ctatgatcag gcttttactt cggttgatag
    35461 cggtcgtgtt gatgtttctc tcaataattt tgacattaca gccaagcggc aaaaaaaata
    35521 caacatctca acgccttata agtatggtgt tgggggaatg attgttcgtg ctgatggcag
    35581 ctcaggcata agcaaggctg acctaagcga ttggaaaggg aaaaaagcag ctggcgcctc
    35641 tggtacagaa tacatgaagg ttgccaagaa gcaaggtgct gaattagtca cttatgataa
    35701 tgtgacgggt gatgtttacc tgaacgatgt tgctaatggc agaacagact ttattcccaa
    35761 tgattatcct gcacaaaagc tttttgtgga ttacatgaag tctcaaaatc ctaacctcaa
    35821 tgtcaaaatg agtgatgtgc tgtataatcc gacagcacag ggcattatca tgagtaaaaa
    35881 agatgacacc cttaagaaaa agattgatgc ggtcatcaaa gacatgaaac aagatggcag
    35941 cttgaaaacc atttcaaaga catactatgc tggtcaggat ttgacagttc cttttggtaa
    36001 ggacaagaaa attccagtca ttgatgccag tgatgtggac tagtgcctta gacaaaggag
    36061 ctctaaagcg atgcttaatc ttagattgat actagagagc ttgggctttg ttttgtcagg
    36121 tttgccctat accttaggca tttctttttt aagctttcta acaggccttt tgctgggctt
    36181 gcttttagcc tttttaaggc gttctactag tcactttagt cattatctgg tcaggagcta
    36241 tgtgtccata atgcgtggcg ttcctatgat tgtggtgctc tttgtccttt attttgggct
    36301 tccctattat ggcttagaac tgtctgcctt gttatgtgcc tatttgggct tttcactggt
    36361 tagtgcagcc tatatctctg aggtctttcg tgcctcgatt gatgctattg atcagggaca
    36421 atgggaggca gcaagggctt tggggctgcc ttatgtcagc attgtcaagc atgtgattct
    36481 gcctcaggcc tttcgtattg ctattccgcc tttaggaaat gttgtgattg atatggtcaa
    36541 aagttcgtct ttggcagcta tgattaccgt tcctgatatt tttcaaaagg ctaaaattat
    36601 tggtggcagg gagtgggatt acatgtctat gtatatcttg gttgccttta tttattgggt
    36661 gattgccttt ttgctggagc gctgtcaggg ctttttagaa aagaggctgc gcttactctc
    36721 ttaaaaaccg aatatttacc ctagaaatat tgtatttcta gggtttttat gataaaaata
    36781 tgatagacta aagtagccta atcagttagt tagctttgtc aagaactgac tggctagagt
    36841 gttggaggta ggatatggca gactctattg tatttcggaa aaatcatatg atttcaactc
    36901 aggcctttgc tcgagtgctg gaagcctcag ggattaaaag accgactaag gacgaggcta
    36961 gattatcgca aatgctaaag cattccaatt atctatggac agcatgggaa ggtgacaagt
    37021 tagttggtgt tgctagagcc cttactgact atgcttatgt ctgctatatt tctgacctag
    37081 cagttgatca ggcatatcag ggtcaaggga taggcaagca attgctgtct tttatctcag
    37141 aggatcttgg agatgctgtt gctcttgtat tgctgtcagc accttcggcg atgtcctatt
    37201 accctaagct tggctttgaa caatcagaca aagccttcat tattccacga aaaccgtttt
    37261 agagaggtat ctaatgacac attcagcttg gcatgatgag attaagcaag tgttacctaa
    37321 ggattattat cggcgtatca atcgcttttt agatgaggtc tatgcgactg gagtggttta
    37381 cccgcccaga gacaatgtgt ttaaggcctt acaggtaacg ccattagaag agacaagagt
    37441 gcttatttta gggcaggacc cttatcatgg ccctcttcaa gctcagggac tttccttttc
    37501 agtgcctgac tccattcctg ctccgccatc tttgcaaaat attttggagg aattagcagc
    37561 agatattgga gtaaggaatc atcacgatct tagcagctgg gctgagcagg gagtgttgct
    37621 cttgaatgcc tgcttgaccg ttccagaagg acgcgccaat gggcatgcag gtctcatctg
    37681 ggagcccttt accgatgcgg ttataaaggt cttgaatgct aaggataggc ctgttgtgtt
    37741 tatcctctgg ggagcctatg cgagaagaaa gaaggccttg attactaatc cgattcacca
    37801 tgttatcgaa agccctcacc ctagccctct gtcagcctat cgtggctttt ttggcagcaa
    37861 gcccttttca agagctaacg ccattttaga aaaagaaggc ctaggacaga ttgactggct
    37921 gcgctaggca ttgaggcagg ctattatggc taagcaggac gatttaccaa taaagtatcc
    37981 ggctttggag acttgggtat acctagctaa atagagattg atgatatcag ggatcaagac
    38041 agttacgtcc gatatgtcaa gcaaaacaaa taatcactgc ctagataaat cagaaattgc
    38101 tagggttatg cttgattatc ctgataagca gataagtaga tttgacatag gaggggtcat
    38161 gttattaatt aaaaatgggc gtgtgatgga tccaaaatca cagctagatc aggtggcaga
    38221 tgtcttaatt gataatggaa ggattttacg gattgctcca gacattgagc atgatgaggt
    38281 agagcagatc gatgccagtg gacttgttgt tgctcctggt ttagtggata ttcatgttca
    38341 ttttagagag ccgggtcaaa cgcacaagga ggacattcat acaggtgctc tggcagcagc
    38401 tgctggtggg gtgacaacag tagtcatgat ggcaaacacc aatcctgtta tatcagatac
    38461 ggaaacctta caggctgttc tagcaagtgc tgctaaagaa aaaattaaca tttataccaa
    38521 tgctagtgtg accaagcggt tcaatggcca agagctaaca gactttaaag cgctcttagc
    38581 agctggtgcg gtcagttttt ctgatgatgg cattccttta gagagctcca aggtcttaaa
    38641 ggaagcattg gatttggcta aggccaacaa gaccttcatt gccctgcatg aggaggatcc
    38701 ccaattaaac ggtgtccttg gcttcaatga gcatatcgct aaggatcatt ttcatttttg
    38761 tggcgctact ggtgtggcag aatatagtat gattgccaga gatgtgatga ttgcctatga
    38821 tcgacaagct catgttcata ttcaacattt atctaaggct gagtctgtta aggtagttgc
    38881 ctttgctcag cagttaggtg ccaaggtcac agccgaggca acaccgcagc atttttctaa
    38941 aacagaagac cttttacggc ttgcaggggc aaatgccaag atgaatccgc ctctaagaac
    39001 agaacaagat agattagcag ttattgaggg gctcaaatca ggtgtcatag ctattattgc
    39061 aacggatcat gcaccacatc atcgtgatga aaaggccgtt gctgatctga ccaaggcacc
    39121 atctggaatg accggcttag aaacctcatt gtcattaggc ctgacaaatc ttgtggagcc
    39181 gagccatctt tcattgatgg cgttattaga gaaaatgacc attaatccag cctcactata
    39241 tagctttgat gctggttatt tggctgagtc tggccctgct gatcttgtta tttttgctga
    39301 caaggaggag cgtttggtaa cagaagcctt tgcttcaaag gctagtaatt caccttttat
    39361 tggcgaaacc ctaaagggag ttgtgaaata caccattgct aagggacaaa ttgtttatca
    39421 ggcagacaac taatcaacac ttaaaaagct gagcatctga tagtaactga tgctcagctt
    39481 tttgatttag tgatggcttg cgggctgctg cttgcttaag ttcaagcccc aaggaatgag
    39541 attttcagat tgctgcttga ttcgcttcat attatcctga tgccttagga taatgattgc
    39601 tgctagcaca acgatggtaa tggttaatag ccaatcgtag ctaggcaata aaaagtgggc
    39661 ggcaggaaaa gtcagaacgc taatcacagc tactacagac gctgttagac tagctagtga
    39721 aatcatgcta aataaataaa gcgttagcac aaacacagcc gctaaaaaaa ggagatagag
    39781 tggggcaaag cctagcaaga caccagcact ggttgcgact gcctttcctc ccttgaagcc
    39841 agcgaaaata ggaaaggtat gccctaggac agcaaaaaag ccaatagtaa ttggtgagat
    39901 attgctagcg ccaaccaaaa ccggaagaag cgtggcaagc gtgcccttaa aaatatcaat
    39961 caataaggtt gcagcaccag cttttagccc aagaatccga aacgtattgg tcgtaccggt
    40021 attacctgag ccatgctcac gcaggttgat gttatagaaa tactgtccaa tccataagcc
    40081 tgttggaatg gagccaagta aatatgctgt aagaattaat aggatcaatt tcataacata
    40141 cattatatca taatgattga tttaagcgga agcagttaca aagaattacg aaaaaatctt
    40201 aaattatttt gcaaaattct caaaaaacct gtaagataaa aaagatgaaa acgtctggag
    40261 gtcaacttgg ctaagaaaga aataagcata acaaattata atgatgatgc cattcaggtc
    40321 ctagagggct tagaggcagt tcgtaaaaga ccagggatgt atatcggatc aaccgatgca
    40381 accggacttc accatttgat ttgggagatt gtcgacaatg ctgttgacga ggccttatct
    40441 ggctttggaa atgagatcga tgtgacgcta aacaaggatg gttctgccac catttctgac
    40501 agcggacgag gcatgccgac cggacagcac gcccttggta taccaactgt tcaggtcatc
    40561 tttaccatct tgcatgcagg tggtaaattt ggtcaaggag gctataaaac ctcaggaggc
    40621 ctgcatggtg tgggctcttc agttgtaaat gccctatcgt catggctaga ggtggaaatc
    40681 acgagagacg gagcggttta caagcagcgc tttgaaaatg gcggtaggcc agtgacaggc
    40741 ttagaaaaaa tagctacagc tccaaaaagc aaatcaggga caagggttac tttcatgcct
    40801 gatgacaaga ttttttcgac aactgagttc aagtggaata ctatcgcaga gcgtctaaag
    40861 gaatctgctt ttctgctaaa gacggttaaa atgaccctga ctgatctacg aggtgacgat
    40921 ccggtcgttg aggaatttca ttatgaaaat ggtgttcagg attttgttgc ctatctcaat
    40981 gaggacaagg aaaccttgac tcctgtgatt tacatggaag ggcaggagca ggattttcag
    41041 gttgaggtcg ctttgcaata caatgatggg ttttcagata acattttgtc ctttgttaac
    41101 aatgttagga caaaggacgg tggcagccat gaaactggct taaaatcagc tattacaaag
    41161 gccatgaatg actatgcccg caaaaccagc ctactaaagg aaaaggataa aaacttggag
    41221 ggctcagatt atcgtgaggg cttgtctgca gtgttatcga tccttgtacc agagcagcat
    41281 ttgcaatttg aagggcaaac aaaggacaag ctaggaagcc cactggcaag gccgatcgtt
    41341 gagagcattg tatcagaaaa gctgaccttc tttttacttg aaaatggtga gctggcaggt
    41401 catttgattc gtaaggctat caaggcaaga gacgcgcgtg aggcagccag aagagcgcgt
    41461 gatgagtctc gaaatggtaa gaaaaacaaa aaggacaagg ggcttctttc tgggaaatta
    41521 actccagccc agtccaaaaa tcctaagaaa aacgagctgt acctagtcga gggggactca
    41581 gctggaggct cagctaagca gggcagggat cgtaaatttc aggcaattct ccccttacgt
    41641 ggtaaggttt tgaacacaga aaaggccaag atggctgata ttctcaaaaa tgaggaaatc
    41701 aatacaatgg tttataccat tggcgcaggt gttggtgctg atttcaatct tgatgatatt
    41761 aattacgaca agattattat catgaccgat gctgatacgg atggggctca tattcagacc
    41821 ctgctgctga cctttttcta ccgttatatg cggccgctgg ttgaagcagg acatgtctat
    41881 attgccttgc ctcctcttta taaaatgtca aagggtaaag gcaaatcgga gaaggtttcc
    41941 tatgcttgga cagatggtga gctggaggat cttcgcaagg aatttggtaa aggtgcaagt
    42001 ctccaacgct ataagggact tggggagatg aatgccgatc agctatggga aaccacgatg
    42061 gaccctgaca cacgaaccct tatccgagtg acgattgatg acctggctag ggcagagcga
    42121 cgcgtttcag tcctcatggg agacaaggct gccccacgcc gtcaatggat tgaggacaat
    42181 gtcaccttta ccttggagga aaatacggtt ttttaaggca tttttcctaa ggagggttct
    42241 aaaatatctc atatcaaatt gctattcatg tgctcagcat tcatttatca aggattgtaa
    42301 tcattgaggt aacagtgatg aagctagata tttgtcaaca aagctacagt cttcagtggg
    42361 gaggcaccta ttattttgca ttgacagatt atcccaatat caaggcttgg gaactggaaa
    42421 agctagcagc cttttgtgcc tacgaaaaat ggaatcatcg tcaaacagac attagctgtc
    42481 aggacagcaa gcttcttgaa gaggttcatc aatttcttga agcacatgct tgtgcctatc
    42541 tctttaggcc tagctgtaaa ttggtggctt caacatttaa catcaatgga gaggcagtct
    42601 gttgtcctta tttaagtcat acctgcactg tagcggctgc tctaagcatt tttaagacag
    42661 gaaggctatt gtctgctgta agagcttttg gggtaacggc acaggagttg gctaggagtg
    42721 atcgaaatgc tgctggtgat cctgctgatt attttcatta tgtgatgctt ggctggtcca
    42781 atacgacctc aggctatcgc ttggctatgg agagattgct taatcgtatg ccaaatgaaa
    42841 aggacttaag agagcatttt gtacccggag ttagctttca ctatagctat tctgatattt
    42901 gtcagatgaa aggctatgtt tttgatggct atcaccctgc caagatcaaa gacgagctta
    42961 gtttggagga attgcaggct tgcattattc ctaaaagctg gcagcagcgc tttgaagcaa
    43021 ttattccaaa ggccttacgc tcaagggttc attacctaga ctataaaggc gaaggcttgg
    43081 tcgagtggtc tgatagggtt tatcagctgt taagagtgat cagtgacagc tagctgtaaa
    43141 taggctagct ttatactatt ttttgaatat aatagacaat ctaacagaaa ggaaagctca
    43201 gtgagaggtc tcttgctggg tgtgggatgg atttcctaga aactgctaat cctagcgata
    43261 ggggagcgta gcgagcccat tctgaaagct cctgccgtag tgaaaagaag ataatcgctt
    43321 acgattatct tcgagggaaa tttcgagccg aagtctcgaa atttaggaat ggaaccgtag
    43381 gttcgcttct gtccccacta cctaaaggaa ctttcaaaaa aaactaatta aagaaagaga
    43441 tatctttctg aaagaaacaa agaaaggaat gttcagctag tttactaact gaacacggga
    43501 ctatttttcc tagaaaaatc ggtaacctcc tagtgtccaa ggacacgtcg tcagttccag
    43561 cattttttac ggaaaaattt cgcaagcgaa acgtcccttt gtatcttatg agtaatattc
    43621 aaaacatgtc ccttgaggac atcatgggag agcgttttgg acgctactcc aaatacatca
    43681 ttcaggagcg agcgcttcct gatattcgag atggtctaaa gcctgttcag cgccgcattc
    43741 tttattctat gaataaggac ggtaatacct ttgaaaaggg ctaccgcaag tcagccaagt
    43801 ctgttggtaa tatcatgggc aatttccacc cgcatggaga ttcttcgatc tatgacgcta
    43861 tggtacgcat gagtcaggat tggaagaatc gtgaaattct tgtggaaatg catggcaata
    43921 acggctcgat ggacggtgat ccaccggcag ctatgcggta cactgaggca agattatctg
    43981 aaattgctgg ttacctgcta caggacatcg ataaaaaaac agtgccattt gcttggaatt
    44041 ttgacgatac cgaaaaagag ccaacagtat tgccagctgc ctttccaaat ctattggtca
    44101 atggctcatc agggatctca gcaggctatg ctacagatat tccaccacat aatttgtcag
    44161 aggtgatcga tgctgttatt tatatgattg accacccaaa tgccaagctg gataagttaa
    44221 tggagctatt gccgggtcct gattttccaa caggtggtat tatccaagga gcagccgaaa
    44281 ttaaaaaagc ctacgaaaca ggtaagagcc gcgttgttgt tcgctccaga actgaaattg
    44341 aggatctaaa gggaggcaag cagcagatca ttgtgaccga acttccttat gaggtcaata
    44401 aagctgtcct agttaaaaaa attgatgatg ttcgggttaa taacaaggtt ccagacatag
    44461 cagaggtgcg tgatgagtca gaccgtacag ggctacgcat tgctattgag ctcaaaaaag
    44521 acgctgacag ccaaaccatc ttgaattatt tgttgaagta taccgagctt caagtcaatt
    44581 ataattttaa tatggttgcg attgatcatt ttacgcctcg tcaggttgga ttgcaaaaaa
    44641 tcttatcaag ctatatcgct caccgcaaaa gtattattat caagcgctct cagtttgaca
    44701 aggaaaaggc tgaaaagaga ttgcatattg ttgagggctt gatacgtgtc ttatctattt
    44761 tagatgagat tatcgcgctg atccgagctt ctgacaataa ggctgacgcc aaggaaaacc
    44821 taaaggtcag ctatgatttt tcagaggaac aagcagaggc tatcgtaacc ttacagcttt
    44881 atcgactgac caatacagat attgttaccc tccagcagga agaacatgac ctaagagagc
    44941 tcatcacaac tctctctgcc attattggtg atgaagcaac catgtataac gtgatgaagc
    45001 gtgagctaag agaggtcaag aaaaagtttg cagggccgcg tttatcagag ctgcaggctg
    45061 aaagccaagc gattgaaatt gattctgcta gtcttatttt ggaggaagaa acctttgtca
    45121 gtgtgactca gggaggctat atcaagcgaa caagccctag gtcatttcac gcctcaagcc
    45181 ttgaggaaat tggtaagcgt gatgatgatc atctgatctt tgttaagcag gctaagacaa
    45241 cagaccacct gttactcttt actaatttag gtaatgttat ttaccgtccg gtctatgagc
    45301 tgactgactt gcgctggaag gacatcgggg agcatttatc acaggctatt gctaattttg
    45361 ctgctgatga gctggtgata tatgctgagt tgatccagtc ctttgaagag ggactatata
    45421 tctcagtgac acagcatgga ctgattaaac ggtttgagcg caaggagctg acgccttggc
    45481 gaacctacaa atcaaaatca attaaatacg ccaagctaaa agacatagat gatcgcattg
    45541 tggcaatagc accaattatc atggaagatc ttcttttggt gacgcagcag ggctacgcct
    45601 tgcggttttc tagccaagaa ataccgattc agggcctaaa ggctgccgga gttaaaggaa
    45661 ttaacctaaa ggctcaggat tacttggttt ctgcctgccc agtcaatgct gattccttct
    45721 ttgtgctgac gcaaagagga gcactaaagc gagtggcgat tgctgatatt ccacagacca
    45781 gccgagctaa cagaggtctg ccggtgttac gagaattaaa gaccaagcca cacagagttt
    45841 tcttggcagg aatggtaaaa ggagatacta caacaggtac cattgactta tttacacatg
    45901 attcagagga cacagctagt gaccagcaat tagaggttat tagtaagact ggtcaacaat
    45961 accagcttgc tctcaatagc ctgtctctat cagataggac aagtaatggc tcctttattt
    46021 cagagagcat ttcagatcag gaggtcgctg ctgcaaggct catctagcca aagctttttc
    46081 gctgtaccag tgagggctct gagtctttca tcgaaaaaag atgcaaaaca atgaagaaaa
    46141 gaatacaaaa agaaaagagg taggataatg acaacagcta ttgattggga aaacttaggc
    46201 tttgaatacc gtaagctgcc atttcgctat gtatcatatt acaaggacgg caaatgggac
    46261 gcaggtcgct taacagaaga tgctaccctg cacatctcag aaagtgcacc agctctgcat
    46321 tatgggcaac aagcctttga aggcttaaag gcctatcgca ctaagaacgg ctctattcag
    46381 ctatttcgcc cagaccgcaa tgcagctcgc ttacaggcaa cagctgaccg tttgctgatg
    46441 ccacaggtat ctaccgagca attcattgac gccgttaagc aagtggtaaa ggcaaatgag
    46501 gattttgtac cgccatatgg aactggtgct accctttacc ttagaccctt gttaattggt
    46561 gttggcgata ttatcggtgt taagcctgct aacgaatata tatttatagt ttttgccatg
    46621 cctgttggca attactttaa aggcgggctt gcgccgacca actttatcgt ctctgaggat
    46681 tatgatagag cagctcctta tggcactgga gctgccaagg ttggtgggaa ctatgcaggt
    46741 agcttattgc caggaaaagc agctaagaca gcagggtatt cagatgtgat ttacctagat
    46801 ccagcaactc acactaagat tgaagaggtc ggagccgcta atttctttgg catcactgcc
    46861 aataatgaat ttattacgcc gcttagccca tcaatcttgc cttcaattac caaatactcc
    46921 ttactccaat tagccgaaga aaggcttggt atgaccgcta ttgagggtga tgtgccgatt
    46981 aatgatttgg accgatttgt tgaggcagga gcttgtggga cagctgctgt gatctcacca
    47041 attggaggca ttcagtatca ggataagcta catgtctttt acagcgagac tgaggttggt
    47101 ccagtgacac gtcgattata cgatgagctg gtcggtatcc aattcggtga tatcgaagca
    47161 ccagaaggct ggattgtagc tattgattaa aataagtgaa gcttgctatt gcaagctctt
    47221 ttgattttgt gtaaaataga caaggcgagg tgaagtgatg agtaaaaaag agaaaaaaat
    47281 tgaactgcaa ttatgcgatc aacaagtaac agtcaacaat accaagatag acggttatca
    47341 gttacaaatt ggcaagcgtg tcgttggcga gattgcagag cttgatggca agtttgctgt
    47401 cttaaaagac agcacagtag atgctttttt taaaacatta gagcaagcag ttgaaaatat
    47461 tattgaaaac tataatttga accactaaaa atgcttaaaa agacttgtca gcttacaaaa
    47521 actatggtag aatagttttt gttgttacgg aaagatagcg aagaggctaa acgcggcgga
    47581 ctgtaaatcc gctcctttgg gttcgggggt tcgaatccct ctctttccat gcctaagcta
    47641 ttaggttcat tgttttaatg atgatattgg ggtatagcca agcggtaagg caagggactt
    47701 tgactccctc atgcgttggt tcgaatccag ctaccccagt cagaggtatc agattagcgt
    47761 ctgagatcgt caaggataaa agttgttgtc attgcgggtt accttgagaa aatatattgt
    47821 tatcaaaagc tagcataagc tagcttttgt tggaggattt tttagaatga atgaatttga
    47881 agatttgcta aacagtgtta gcgaagtcaa tcctggtgat gttgtcactg cggaggtttt
    47941 gacagttgat aacggtcaag caaacgttgt tattgaaggc acaggtgttg aaggcgtttt
    48001 gacacttcgt gaattgacta acgatcgtga agctgatatt aatgactatg ttaaagctgg
    48061 cgacaccgtt gaagtgcttg ttcttcgtca agttgtaggt aaagatactg atacagttac
    48121 tttcctagta tctaaaaaac gtttggaagc tcgtaaggca tgggacaagc ttattggtcg
    48181 tgaaggtgaa gtcgttactg ttaaggggac tcgtgctgtt aaaggtggac tttcagttga
    48241 atttgaaggg cttcgcggat ttatccctgc ttcaatgatt gacactcgtt ttgttcgcaa
    48301 tacagaaaag tttgtcggtc aagaatttga cgctaaaatc aaagaagttg atgcagcaga
    48361 aaaccgcttt atcttatcac gtcgtgaggt tgttgaagaa gcagctaagc aagcacgtga
    48421 caaagtcttt tcaacacttt cagaaggttc agtggtaact ggtactgttg cgcgtttgac
    48481 aagctttggt gcttttattg atcttggtgg tgttgacggt cttgttcacg taactgagct
    48541 ctcacatgag cgtaatgtgt cgcctaaatc agttgtttct gttggtgaag aggttgaggt
    48601 gaaggtactt gctcttgatg aggaagcagg tcgcgtatca ctatcactta aagcaacaac
    48661 acctggacct tgggatggcg ttgagcaaaa gcttgcacaa ggtgatgtta tcgaaggtaa
    48721 ggttaagcgc ttgactgact ttggtgcttt tgttgaggta ttacctggaa ttgatggact
    48781 tgtacacatt tcacaaatct cacacaagcg tgttgaaaat ccaaaggacg tgcttactgt
    48841 aggtcaagag gtaactgtta aggttcttga cgttaacgct gctgatgagc gtgtatcatt
    48901 gtcaatcaag gcacttgaag agcgtccagc acaagcagag ggtgaaaagg aagaaaaacg
    48961 tcaatcacgt ccacgtcatc aaaaacgtga agctaagcgt gattatgagc ttccagaaac
    49021 acaaactgga ttttcaatgg ctgacctttt tggtgatatt gaattataat actataaaaa
//
LOCUS       DARYXZ010000011        48181 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYXZ010000011 DARYXZ010000000
VERSION     DARYXZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48181
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TV186_000538"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TV186_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL1531961.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TV186_000539"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TV186_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TV186_000540"
     CDS             1286..2599
                     /locus_tag="TV186_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1531962.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TV186_000541"
     CDS             2700..3587
                     /locus_tag="TV186_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1531963.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TV186_000542"
     CDS             3600..4430
                     /locus_tag="TV186_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1531964.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TV186_000543"
     CDS             4446..4901
                     /locus_tag="TV186_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL1531965.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TV186_000544"
     CDS             4926..5576
                     /locus_tag="TV186_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL1531966.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TV186_000545"
     CDS             5605..6525
                     /locus_tag="TV186_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL1531967.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TV186_000546"
     CDS             6540..7424
                     /locus_tag="TV186_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1531968.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            7424..7696
                     /locus_tag="TV186_000547"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TV186_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TV186_000548"
     CDS             complement(7738..8562)
                     /locus_tag="TV186_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL1531969.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TV186_000549"
     CDS             8791..9564
                     /locus_tag="TV186_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL1531970.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TV186_000550"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TV186_000550"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL1531971.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TV186_000551"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TV186_000551"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL1531972.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TV186_000552"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TV186_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL1531973.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TV186_000553"
     CDS             12390..13052
                     /locus_tag="TV186_000553"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL1531974.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TV186_000554"
     CDS             13045..13677
                     /locus_tag="TV186_000554"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL1531975.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TV186_000555"
     CDS             13679..14950
                     /locus_tag="TV186_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL1531976.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TV186_000556"
     CDS             14940..15878
                     /locus_tag="TV186_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL1531977.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TV186_000557"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TV186_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL1531978.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TV186_000558"
     CDS             16830..19334
                     /locus_tag="TV186_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL1531979.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TV186_000559"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TV186_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL1531980.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TV186_000560"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TV186_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL1531981.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TV186_000561"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TV186_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL1531982.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23059..23277
                     /locus_tag="TV186_000562"
     CDS             23059..23277
                     /locus_tag="TV186_000562"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1531983.1"
                     /translation="MDSIPAFLMCYNRWAVQQLIKAMTEKSSPIRHKRLGKGLKKALL
                     TTLSDTFGCPKKLFAVSILMEKQSFENG"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TV186_000563"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TV186_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL1531984.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAYL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TV186_000564"
     CDS             24977..25831
                     /locus_tag="TV186_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL1531985.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TV186_000565"
     CDS             26041..27237
                     /locus_tag="TV186_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL1531986.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYEAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TV186_000566"
     CDS             27660..28181
                     /locus_tag="TV186_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1531987.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TV186_000567"
     CDS             28257..28628
                     /locus_tag="TV186_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1531988.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TV186_000568"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TV186_000568"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL1531989.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            30244..31902
                     /locus_tag="TV186_000569"
     CDS             30244..31902
                     /locus_tag="TV186_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1531990.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            32071..32985
                     /locus_tag="TV186_000570"
     CDS             32071..32985
                     /locus_tag="TV186_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531991.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            32995..34026
                     /locus_tag="TV186_000571"
     CDS             32995..34026
                     /locus_tag="TV186_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1531992.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            34038..35084
                     /locus_tag="TV186_000572"
     CDS             34038..35084
                     /locus_tag="TV186_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1531993.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            35084..36019
                     /locus_tag="TV186_000573"
     CDS             35084..36019
                     /locus_tag="TV186_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1531994.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(36648..38330)
                     /locus_tag="TV186_000574"
     CDS             complement(36648..38330)
                     /locus_tag="TV186_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1531995.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(38332..38562)
                     /locus_tag="TV186_000575"
     CDS             complement(38332..38562)
                     /locus_tag="TV186_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL1531996.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            38848..39546
                     /gene="tsaB"
                     /locus_tag="TV186_000576"
     CDS             38848..39546
                     /gene="tsaB"
                     /locus_tag="TV186_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL1531997.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            39549..39974
                     /gene="rimI"
                     /locus_tag="TV186_000577"
     CDS             39549..39974
                     /gene="rimI"
                     /locus_tag="TV186_000577"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL1531998.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            39964..40980
                     /gene="tsaD"
                     /locus_tag="TV186_000578"
     CDS             39964..40980
                     /gene="tsaD"
                     /locus_tag="TV186_000578"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL1531999.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            41002..42030
                     /locus_tag="TV186_000579"
     CDS             41002..42030
                     /locus_tag="TV186_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL1532000.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TV186_000580"
     CDS             complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TV186_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL1532001.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(42888..44060)
                     /locus_tag="TV186_000581"
     CDS             complement(42888..44060)
                     /locus_tag="TV186_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1532002.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            44186..44716
                     /locus_tag="TV186_000582"
     CDS             44186..44716
                     /locus_tag="TV186_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL1532003.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            44761..45348
                     /locus_tag="TV186_000583"
     CDS             44761..45348
                     /locus_tag="TV186_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL1532004.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            45452..46174
                     /locus_tag="TV186_000584"
     CDS             45452..46174
                     /locus_tag="TV186_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1532005.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(46216..46515)
                     /locus_tag="TV186_000585"
     CDS             complement(46216..46515)
                     /locus_tag="TV186_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL1532006.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            46913..47500
                     /locus_tag="TV186_000586"
     CDS             46913..47500
                     /locus_tag="TV186_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532007.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            47639..>48181
                     /locus_tag="TV186_000587"
     CDS             47639..>48181
                     /locus_tag="TV186_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1532008.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT        13643 a         9419 c        11267 g        13852 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct acaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctc
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcata tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctacg aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gctatgagga cagaagtgtc
    30121 tggtttatct atttataaaa ataaaatcaa aaattttcag ataaatctat ttcctttttt
    30181 cagaattatg gtataatcta atttaattat tttaaataac tattttgtta ggaggaaggt
    30241 tatatgacag tactaggaac aaaagcatgt aagcgtctgg gcttagcggc agttacgcta
    30301 gcctctgttg ctgccttgat ggcttgtgga aataagcaat cagcgtcaac agacaaaaag
    30361 agtgagatta attggtatac gccaactgag atcatcacac ttgatatctc aaaaaataca
    30421 gatacctatt ctgctttggc tattggtaat tctggcagta accttttgcg tgctgatgct
    30481 aaggggaaat tacagcctga tttggctgaa aaggttgatg tgtcagagga cggcttgacc
    30541 tatacagcaa ccctgcgaga tggcttgaaa tggtctgatg gtagtgatct aacagcagag
    30601 gactttgtgt acagctggca gcgaatggtc gatcctaaga cagcctcaga gtacgcttac
    30661 ttggcaactg agtcacatct gaaaaacgca gaggacatta atagcgggaa aaatcctgat
    30721 ctagactctc taggggtaaa ggctgatggg aataaggtta tttttacctt aacggagcca
    30781 gcaccacaat ttaagagctt gctgtccttc tctaactttg ttcctcaaaa agaatccttt
    30841 gtcaaggacg ctggcaagga ctatgggaca acatcagaaa aacaaattta ttctggtcct
    30901 tatattgtca aggactggaa tggcactagc ggaaccttta agctagtaaa gaataaaaac
    30961 tattgggacg ccaaaaacgt caaaactgag acagttaatg ttcaaacggt taaaaagcca
    31021 gatacagctg ttcaaatgta caagcaaggt aagctagact ttgcaaatat ttctggtacc
    31081 tcagctattt acaatgctaa taaaaagcat aaggacgttg ttccggttct tgaggcaaca
    31141 acagcctata tcgtatataa ccagacagga gctattgaag gcttgaacag tcttaaaatt
    31201 cgtcaagcct tgaatttggc aacagaccgt aagggaattg tatctgcggc tgttgataca
    31261 ggctcaaagc cggctacagc gctggttcct acaggtcttg ctaaattatc tgacggaaca
    31321 gatctaacag agcatgtggc acctggctat aaatacgatg acaaggaagc tgcaaagctc
    31381 ttcaaggaag gcttggcaga gctgggcaag gatgccttga caatcaccat cacagctgat
    31441 gctgatgcgc cggctgccaa gtctgcagtg gattacatca aggaaacctg ggaaacagct
    31501 cttcctggct tgaccgttga agagaaattt gttcctttca agcaacgtct tgaggatact
    31561 aaaaaccaaa actttgaggt tgcagttgtt ctttggggtg gtgattatcc aaaagggtct
    31621 accttctatg gcttgtttaa atcagggtct gcttataact atggtaaatt tacgaatgca
    31681 gactatgatg cggcctacaa caaggctcta acaacagatg ccttgaatac agatgcggct
    31741 gctgatgatt ataaggcggc agaaaaagcc ctttatgaca atgcccttta caatcccctt
    31801 tacttccgta gcggtgaagg cctgcaaaat ccaagcatca aaggtcttat ccgtaattca
    31861 actggtctaa atgttgactt tacttacgct tataaggact agcaataata ttattgtaag
    31921 cctatactga cctagcaagg ccacagctcc ttgatgggaa gtgtttaaga gaagcttagg
    31981 gctagctagg agtgtctatc ctgtaggcct tggcaagcat attgcaagaa ttggtcttaa
    32041 ccagttcttg cttttggtta gaggaaaaat atgattaaat atcttttgaa gcgagtggct
    32101 attttagtag tgacactctg ggtggtgatt accctgtcct tctttttgat gcaggtgatg
    32161 cctggaacac cctataacag tcctaaatta actgatgaca tgattgctat gctgaatcag
    32221 cagtacggct tagataagcc tctttggcag caatatttga agtatttgtt tgatattctt
    32281 catggtgact ttggcaccag ctatcagtcg attaatcaat cagtgacaac cctgatctcg
    32341 cagcgtctgg gggtatctgt gcacttagga gtacaggcgc ttattgttgg tattagctct
    32401 ggcttagctg ttggtgctgt ctcagcgcgg aataaaaata atagcattga tgccatttta
    32461 agtgttatct caacgcttgg tatttccatg ccgtccttta tcattggctt gctgctgctg
    32521 gattatttgg gctttaaatg gaatttactt cccttgtctg gctggggaag ctttgggcaa
    32581 acgattttgc cgacgcttgc tttagctatt ccggtctttg ctcaggtgac ccgttttttc
    32641 cgcagcgaga tgatcgagac cttatcgaca gattatattc agctagctag ggcgaagggc
    32701 ttgactaagc gtcaggtgac tcgtcggcat gcttaccgca attcgatgat tcctgtgtta
    32761 accttggttg gtccgatggc tgctggtatt ttgacgggat cagccctgat tgagcagatt
    32821 ttttccattc cggggattgg gcagcagttt gtgacctcta ttcccaccaa ggattaccca
    32881 gtgattatgg gaacaacgat tgtctatgcg ctaatgctga tggttgctat tttggcaact
    32941 gatatgatca ttagtatcgc agatccacgt gttcgtttgg gataggagag tgctatgcta
    33001 gaagaaacaa aatcatttaa gcttgttgga gcaggtagct tagcgacaca agaaaaaatt
    33061 gaaaagccgg cgctttcctt tcttcaggac gcttggcgta ggctaaagca caataaacta
    33121 gctgttattg cgatggggtt tttagctgtg ctgcttttgt tttctattgg ttctttattt
    33181 gttgtatcta cagatgatgc caatagcttt aacagtaagg aggtaagcat ataccgtaac
    33241 ctgccgccaa agctaagcag cagcttgcca ttttggaatg ggaccattac ctacgctggt
    33301 aatacagagc ccaatgacgc ttatgcggat caaggggtcc cagaggacaa ggccttctta
    33361 ctcgggacgg ataatctggg gcgcagtatt ggaaaacgta ttacggtagg gattcgtatt
    33421 tctcttttga ttgctattgt cgcaaccctg atcgatctag tgattggggt aacctatggc
    33481 ttggtctcag gctttgttgg tggcaagact gacatggtga tgcagcggat cattgagatt
    33541 atctcctcta ttccaaacct tgttattgtg accatgcttg gtcttttgct tggcaatggt
    33601 gtgacttcaa ttattatttc aattgcgatt gtaggctgga cctcaatggc taggcaggtc
    33661 cgcaacctaa ccctgtctta tcgagagcgt gatttcgtcc ttgcttctcg tgccttggga
    33721 gaaagtaata tcaggattgc ctttaagcat gtattgccaa atatttcagg gattattatt
    33781 gttcaaatca tgatgactgt tccgagtgct atcatgtatg agtcagtttt atctgcgatt
    33841 aatttaggcg ttaagccacc gacagcttcg attggttcat tgattactga tgcacaagaa
    33901 agcctgcaat attatcctta tcaggtgctg ctgccggctt ttgccttggt gttaatttcg
    33961 ctagccttta ttttgttggg tgatggcttg cgtgacgctt ttgatccaaa atcaagtgat
    34021 gaataggggg aaataaaatg acgaatgaaa ccattttaag tgtcaaaaac ctccatgttg
    34081 attttaaaac ctacgctgga gatgttaagg cgattcgtga tatcagcttt gagctaaaaa
    34141 agggagagac tcttgcgatt gtgggagaat caggctcagg gaaatctgta accactcgca
    34201 cgctgatggg gttaaatgct aagaatgcaa gtatttcagg gaatatttgc tttaagggca
    34261 agcagctcaa tgagctgaag gaggaggaat gggtcaaggt gcgtggcaat gaaattgcaa
    34321 tgatcttcca ggatccgatg accagccttg atcctaccat gacaattggc atgcagattg
    34381 cagaggcaat aatgattcat caaagcattc ataagacaga agccttgaag cgtgctttag
    34441 acctgatgcg tcaggttggt atcccaaatg ctgaggagca ccttaaggat tacccacatc
    34501 agtggtctgg gggcatgcgg caacgggctg ttattgccat tgctctagct gccaatcctg
    34561 atattttgat tgcagatgag ccgacaacag ctcttgatgt taccattcag gcccagattt
    34621 tgaagctgat gaaggatatt cagtctcaga ccgcatcatc gattatcttt attacgcatg
    34681 accttggtgt tgttgctgga atggtagatc gcgttgctgt catgtatgct ggaaagattg
    34741 tcgaatatgg aacggttgac gaggtatttt atcatccgca gcacccttat acctggggct
    34801 tgctcaattc gatgccaaca acagctactg cagcaggtag cttgaggtct attcccggaa
    34861 cgccgccaga tttattaaac cctccaaagg gagatgcttt tgctgcccgt aatgagtttg
    34921 ccctagacat tgaccatatc aaagagcctc caatgttcaa ggtaagtgac agccactacg
    34981 cagcaacctg gttgctagat gagcgtgctc ctaaaataac ccctccattc ccaatccgca
    35041 agcgttgggc aaaatggcag gaaatggaag agaggaaggc ttaatgacag aagctcgtaa
    35101 aaaattaatc gaagtaaaga atgtttcctt aacctttaac aaggggaaga aaaacgaggt
    35161 taaggctatt gatcgcctta gctttgacat ttatgagggg gaagtatttg gccttgttgg
    35221 ggaatcaggc tcaggcaaga cgacagttgg tcgagctatt ttgaaactgt atgacattag
    35281 tgatggtgag attatcttta acggagaaaa tgtctcccaa ttaaaaggga aaaagctgca
    35341 tagctttcgt aagcatgcac aaatgatctt ccaagatcct caggctagtt tgaacggccg
    35401 tatgaaaatt agagacattg ttgcagaggg cttagacatt catggcttga cagcctcaaa
    35461 ggcagagcgt gaagcaagag tccaggagct gttaaagctt gttgggctca atcagaacca
    35521 tttgacgcgc tacccacatg aattttccgg tggtcaacgc cagcgaattg gcattgcgcg
    35581 tgccttggct gtgaagccga cctttattat cgcagatgag ccgatttcag cgcttgatgt
    35641 gtcgattcaa gcacaggtag tgagtctcat gcagcaattg caaaaaaagc gtggcttgac
    35701 ctatctcttt atcgctcacg atttgtctat ggtcaaatac atttcagacc gtattggtgt
    35761 gatgcattgg ggcaaaatgc ttgagattgg gacatctgat gaggtttaca atcacccgat
    35821 tcacccttat acgaaaagct tgatctcggc cattcctgag ccggatcctg aaaaggagcg
    35881 taagcgtatt gcagaggttt atgatcctag ccaggagcta gatggccaag agcgacaaat
    35941 gcatgaaatc actcctgggc attttgtctt agcgactcag gccgaagccg agcagtaccg
    36001 agcagagtgt ggcctttaag agactagcat aacagcaatt tcctaaaaag gctgatgtga
    36061 tagtttttta ggtatgacag accaaaagtc gtatgacctt tgccgatcaa aagcaggtgc
    36121 catgcgattt tggtggtatg gtggagcttt gtcagccaac ctagactgca caaaaagctc
    36181 cttatgatag aatttgtagc atgaggttgc gacacaagtc taccctaaaa taaaacaaaa
    36241 taaaacaacc gaacaggtct agctttctga gatttcaaaa gccagacctg ttcggttttt
    36301 aatgaatgag actaggtcat aaagtatctt agttaagatt gtctaaagtg cagctctttt
    36361 tgctgtgctt gctgctgttt ttataaaatg actcgtggga atcaatcagc ctgtagtcaa
    36421 atgttatcgc tctctttttg agatgtggct tgacaggttt gctaagctca gcaggctatt
    36481 tttagtagta tagctagaca aaggccctta agctagctca gcacgtcact ctgttaagct
    36541 tagctaacag cacgtgttgg gcaagtagta tgcctcatag ccttgtacgt cagtcattga
    36601 cgttgacgca acaaaaaaac acgagtctct aagctcgtgt caaagatcta ttggctatca
    36661 ggcgttagaa ccatcggaat gataataggc tcgcgctctg tcttttcgta aaggaaggga
    36721 cgaagcgcat taacgatagc accattgaca gactggatac tagcgtcctt atttttcaga
    36781 gcgatacgaa tcgcattgaa aagcacgcgc tgactctctc tgatgagctc gcctgactcg
    36841 cgcatgtaga taaagccgcg gctgagaata tctggtccgg ctaagatcat ctgtgtctca
    36901 aaatcaacag tcgccactgc aaggacaacc ccgtcctctg aaagatcacg acgatcgcga
    36961 aggactgctg tcccaatatc tccaatgcca ttgccatcta cataaatgtc ctgagcattg
    37021 aaatgaccgg ctatacgagc gctatcactg gtcaaggcca atacgtcacc attttccatg
    37081 ataaagatat tttcctctgg aatcccaata tcaacagcaa gcccagcatg aaccttctgc
    37141 atacggtatt caccatggac aggcataaag tattttggct taataaggct aagcattagc
    37201 ttttgctcct gctggccacc atgaccggag gtgtggatat tgttgacctt tccatgaata
    37261 acgtcaactc cagcctcctg aatcgtattg attagcttat tgacgctgac ggtattacca
    37321 ggaattggac ttgatgaaaa gatgacagtg tctccaggct gtaagctgac ctgtctgtgg
    37381 gtaccattgg caatcctagc aagggcggcc atagactccc cttgactgcc ggtacacatg
    37441 atcaaaatct cactagcgtg gtaatgttta atctcattag gctcaataaa ggttcccttt
    37501 gggaccttga tgtagccaag ctcaataccg ttaacaatag ccttttccat tgaacgacca
    37561 aatacagcaa tcttacgccc tgtcttaaca gcggcttctg cagcctgctg caagcggtag
    37621 atatttgaag caaaggaagc aaaaatgata cgtccatgaa tgccttcaat aatgttcatg
    37681 attgactggc caacgacctt ttcagaattc gtaaaggttg gtatctcggc atttgtcgaa
    37741 tcggacaata gacaaagaac cccgtcctta ccaagagcag ccatgcgatg tagatcagcc
    37801 ggatcaccaa caggtgtaaa gtcaaacttg aagtcgccag tacagatgac tttcccttgt
    37861 ggggtgtgga taacaatccc aagtggctct ggaatagagt gagttgtttt aaagaaggta
    37921 acgctcatat gcttaaaggt gagctcggta ttgtgattaa tctcatagag cacagcatcg
    37981 cgtaagagac cgtgctcctc cagctttcct cggataagag ctagagctaa ggggcctgca
    38041 tatataggca cattagcttg ctttagtaaa aaaggaatac cgccaatatg atcctcatga
    38101 ccatgagtaa tcacaagagc cttgacgcgc tccaaattgt caacaatata agagtaatcg
    38161 gggataacat agtcaatccc tagcagatcg tcctctggga atttgatacc ggcatcgaca
    38221 atgatgattt catcttgata ctcaataccg taggtgtttt tgccgatctc tcccagacca
    38281 ccaatcgcat aaaccccaac ctcattaggc cttaaactga tatttgtcat gttaaaactc
    38341 cgttaatgtg aaaacaccag tttctttttc gtagtctagg tgcttgtctg agagcagctc
    38401 gatgaattcg acattgtaat cggtgtgctc ttcaaccatc ttgcgggctt tgatacgccc
    38461 ctcaagctca cttgcagcgt ctatatctag gtatagggcc tgtgtgtttt cacgacgcgg
    38521 actgcgttcc tttgtttctt ggtagaaaac tttataaatc attgatgata tcttcctttc
    38581 atgatgaatc gattatccaa acaataacaa ataggtcaaa acgagaaggc ctctgttttg
    38641 acgattacct atcatgtgat tattgtgtaa tagatttaaa cctgattctg tgcaattact
    38701 aagattatac catactatcg gcttttagta aaaagtttcg ataaaattat tctcttgacc
    38761 ggtgatgagg ctgtggctgt ctccttttcc atgaccttta ttttatgtta taattgtgga
    38821 atagaaatga cttgagaagg gcttagtatg aagacacttg catttgacac atcaaataag
    38881 gcattatctg ttgctctatt agacgatggc acattattgg ctgatcttac gattaatgtt
    38941 aagaagaatc acagtattag tctgatgccg gctattgatt ttttaatgtc ctcagctgac
    39001 ctgaagccaa aggatcttga tcggatcgta gtagcagaag ggccgggctc ctatactggc
    39061 ttgcgtgttg ctactgctac agcaaaaatg cttgcttata gcctaagtat tgacctcgtt
    39121 ggcgtatcaa gcctatatgc cctagcggct tctacttgcc gagaaaaccc tgatagcttg
    39181 gttgtccctt tgattgatgc tagacgacgc catgtttatg tgggctatta tcaccatcaa
    39241 aaagctgtga aacaggataa gtacgcgtcc tttgatgctg ttttagcaga actggtctct
    39301 tgtgaccatg tgatttttgt tggagaagtg gagggctttg cagaggacat tcgatcagcc
    39361 ttgccagagg ccaagataaa gccaagtctg ccatcggctt ttgaggttgg tttgctaggc
    39421 agcagccttt cagctgacaa tgtagcagcc tttgtcccac aatatttgaa gcgggtcgag
    39481 gcagaggaaa actggctcaa aactcatgct gccggtgatg acagccagta tgtcaagcga
    39541 gtttagcgat gatgtctatc caagaaaaag cagcagctgt ctatcaggtg ctaaaagagg
    39601 tctatggtca atccccttgg accttaaagc agatagtgtc tgatatgcag caggagcatg
    39661 ttgattattt taccttttat catcaggaga ccctgctagg ttttttagcg attcaacagc
    39721 tgccaggaga aatggaaatc actaatctag ctgttttgcc aagctatcag gggcaaggga
    39781 ttgcctcttg gctcatggga cagctagatg gctttgaggg agtgatattt cttgaggtta
    39841 gagcgtcaaa ccatagggcg cagcagcttt accttaagca tggctttgag gtggtaggcc
    39901 agcgtagcaa ttattatcat gatccaatag aagcagcctt gatcatgagg cgggaaggaa
    39961 agaatgacag atagatatat tttagcagtg gagagctctt gtgatgagac aagtgttgct
    40021 atcttaaaaa acgacaacgt cttattgacc aatattattg ctagtcaggt tgaaagtcac
    40081 aagcgttttg gtggagtggt tcctgaagtg gctagtcgtc atcatgtgga ggtgattacg
    40141 acttgctttg atgacgcact caaggaggcc cagcttgagg cttctgactt gactgcggtt
    40201 gcggttacct atggaccagg tctggtgggg gccttgctag ttggcctagc agcagccaag
    40261 gcctttgctt gggctaatga tttgcccttg attccagtca atcatatggc agggcacctg
    40321 atggcggcac gcgagcaagg agagctggaa taccctctta tggctctctt ggtttctggt
    40381 gggcatacag agcttgtcta tgtgaccgag ccaggagaat atcatattgt tggagaaaca
    40441 cgtgatgacg cagttggtga ggcctatgat aaggtaggac gtgtgatggg cttgccctat
    40501 cctgctggtc gtgagattga tcagctagct caccaaggga cagataccta tcattttcct
    40561 cgtgccatga tgaaagagga tcatttagaa ttttcttttt caggcctaaa atcagccttt
    40621 atcaacctgc accataatgc gcagcaaaag ggtgaggagc ttgtgcttga ggatctctgt
    40681 gcttcctttc aggctgcggt gttagatata ttgttagcaa aaacgaagaa ggcactcaag
    40741 cagtatccat caaaaatgct agtcgttgca ggtggagtgg cagctaatca gggacttcgt
    40801 gagcgtttag ctgaggaaat aactgatata gctgttgtga taccacctct aagattgtgt
    40861 ggagataatg ctggtatgat tgcgttggcg gcggtggttg agtacgagaa agggcatgtg
    40921 gcaggcttgg atctaaatgc taagccgagt ctagcctttg atagctttca tcagcagtag
    40981 tattagtatg aggagattgt catgttttat ttattgcttc ccccattgat ttgcagtgtg
    41041 gtatttttgg ctgtctatat taaggagcca agaacgctgt ggctaggagc tagctttgtg
    41101 acgaccctag gtgttagtct cttgtgtgct atgatttaca ttttttcaat cgaagaaaag
    41161 cttcagggag ttggtatcct agtgctaggt gttattgggt ttcttgcgat tgtatggttg
    41221 atgtctagtc cctttatcct cttgctcttt ctaagcttta atggcattag gctcatcaaa
    41281 agagaggggc tttcctttcg gaatttattg ctgattggct cagcggtgct attgtttgta
    41341 catcctttta tcagcagact attgttagag agtatcggtg attcaaagct tttaaggatc
    41401 atgtatgaaa cgagtgacct cttaatcctt tacctcttgt taatcgtatc agtctacacc
    41461 atctcaagca tgctgaatac cttttacttc agaaaaacca aggaggatta tattattgtg
    41521 ctgggcagcg gcttaaatgg agaccaggtc acccccttgc tagctagccg cattaataag
    41581 ggcattcaga tttaccagaa aaatcctggc agcaagctga tcatgtctgg tggcaaaggg
    41641 gctgatgagc taatagctga gggtgaggcg atgtgtcgct atgcaatcca gcaaggaatc
    41701 aaaagtgaag atatattagt tgaaaaccaa tccagaaaca ccagagaaaa tattctgttg
    41761 tctaagcaat taataccatc tggagcttcc ttttgcttgg tgaccaatcg ttaccacctg
    41821 tttagagcct tattactggc taaggagcta gccttgcctt gcaggtgcta tggggcaaaa
    41881 acaaagctct actttagtat gaatgccttt atcagagaga ttgttggcta tctccaatta
    41941 aagaaaaagc agcacctgct ggcaatgctc atcttaacag taggctatat agccataaga
    42001 gtggtgatga tctatatgct gcacatttga tgtcattggc aaaaaagcta aggctagtca
    42061 cctcgtcttg ggctgaaaaa gtctctctta ggtccttttc tcagatgata tgagcaagca
    42121 gcctttttaa aaaggctaca tctaggattt tatggagcct tagagcttgt tgtgtggtga
    42181 tgttcaatgg aaccaatcac aattgttaca gcaaaaagca ggcctttagg aacgtttgct
    42241 ttgctggtaa gtccttttac ttgcagaggc tggctacacc agccaaaggc taaggcaagt
    42301 gatttagctt gtgatgatca aggagtttta agacgtaaaa aaatagctcg gtatcttggc
    42361 ataccgagct atcatgataa attggcttct atgattacta aatcttaaac aaggtgagtc
    42421 aagcttacca gctagcctta gtgattcctg gtagttggcc tttgtgagct agctcacgaa
    42481 aattgatacg gctgacacca aacttacgca tgtaagcatg gggacggcca tcaattctat
    42541 cacgattttt caagcgattt ggatttgaat cacgtggcaa tttgcgcagt gcttcataat
    42601 caccctttgc tttaagctcg cgacgaaggt cagcatactg ttcaatcagt tggagctgct
    42661 tatggtattt agcaattttt gacttctttg ccattgcttt ctccttctta atatttaata
    42721 atctcagagc gttatcagca ccctgaattt cctcaaccag tcattaatca gttaagaaaa
    42781 catagctcta ttatacacta atttcaatca aatgcaagaa aaatagataa ctgattaacc
    42841 agttgaggca aaaacagcct gccagtgagt ctactgacaa gcctagctta gctttgcgag
    42901 cttcctgcca cccagccaga gcagagggca gctgtaatgt taaagccacc tgtatgagca
    42961 ttaacatcta agacctcacc agcaaagtaa agtcccgcga cctttttgct ttctagggtc
    43021 ttagggttga tttcttttaa gtcaatgcca cccttggtta caaaggattt ggccagagat
    43081 atttttcctg tgattggaat cggtaattgc ttaatcctgt tgacgagctc ctgagtctgt
    43141 gtgggagtta actgctttcc tttttctgga tagccctttg ctaaaaaatc agcgactcgc
    43201 tcaggcatca aagtcttgag cgcattttta agggcctttt cccggtgctg cgctagatag
    43261 ctgagcagct cagctgcgga ggtttgtggc agcaggtcaa gctctgcgat gtcacctccc
    43321 ttaacaaagg aggaaagcct gagagcagcg gggcctgaca acccaaaatg ggtaaaaagc
    43381 aaatcgtgag tgatctgatg tttcccacag ctaagggtca catcagcaag tgaaatcccc
    43441 tgcagagcct tatgtggaaa gtctgttaat aaggggcttt ccgcagcctc tagctcggtg
    43501 acagctatgt taaagtggcg agcaatatca tagccaaagc ctgtcgatcc agtagatggg
    43561 taggacttgc ctcctgttgc cacgataagc ctctcgcagc tgaaggtttg atcaactgat
    43621 ttgaggtaaa aaaggttatt ccgctttttg accgagacaa tctcggtact gatcagcacc
    43681 tgagctccta gtgacttgat tttttgctcc agcgcattga taatcgtctt tgattgatcg
    43741 gtcgtaggaa acatgcgtcc atgatcctct tccttgaggg tcaccccatt ttccttgaaa
    43801 aaggcaatga tgtcatgatt atcaaattgg gaaaagacgc tatagagaaa gcgcccgtta
    43861 ccgggaatgc ccgcgattag ctcatcatgg cttccgctat tggtgacatt gcagcgtcct
    43921 cctccagtcc ctgctagctt tttgcctagg cgcttgtttt tgtcaagtag gagtgtcttg
    43981 tagccatagt agctactaga gatggctgcc atcataccag caggaccacc tccaataata
    44041 atcgtgtcgt atagtatcat gtgcttattt tagcataaca tcaagcgatt taacagtaat
    44101 gtaaactagg ctaaattgac agaattctgg tattgtgtta ctatttttaa taagaatatt
    44161 cagttacagt aataaagagg aaattatggc aatagaaaag acagttagtg aactagctga
    44221 cattttggga gtgagccgcc aggctgtcaa taatcgtgtc aagtccttac cagaggagga
    44281 ccttgataaa aatgataaag gggtcactgt cgttaagcgt agtggcttgg ttaagctgga
    44341 ggaaatctac aagaaaacca tttttgatga tgagccaatt agtgaagaga ccaagcagcg
    44401 tgagctctta gagattctgg ttgacgaaaa aaacactgaa atcactcgct tatatgagca
    44461 gctaaaggca aaggatagcc agctggctgc taaggacgag cagatgcgta ttaaggacgt
    44521 tcagattgcc gagaaggaca agcagctgga tcagcagcag cagctgacag ctaaggctat
    44581 ggcagacaaa gagaccttga agctggagct tgaggaagca aaggctgagg ctgatcaggt
    44641 acgactgcaa gcagaggaga tacagtctga aatgggacct aaaaaaggtt ttttaaatcg
    44701 tttatttggt aaataacagt ataccaagac cctctaaggg tcttttttga ggagagaaga
    44761 atgaaacaat tagaagcata tattgccttt gatatggaat ttaatactgt caatgaggtt
    44821 agtcatatca ttcagctttc agcggtcaaa tggcacaagc atcaggaggt tgacagcttt
    44881 gacagctatg tttacactgc tgttcccctg caaagcttta tcaatggcct gacaggcatt
    44941 acctcagata agatcgtatc agcacccaag gttgatgagg tgcttgatgc ctttaagcaa
    45001 tttgtcggtg acacgccttt gataggctat aatgcacaaa agtctgattt gcctatttta
    45061 gcagcaaatg gcttggatct gtcagcgcaa tatgcagtcg atgtctttga tgaagcctat
    45121 gagagacgaa gcagcgacct aaacgggatt gctaatcttc gcctgcaaac agttgctgat
    45181 tttttaggga taaaaggaag aggacataat agcttagagg acgctcgtat gacagcgcgt
    45241 gtctatgaag cgtttgtgga atttgacgac aataagtctt acctaaacaa acaaaaagaa
    45301 gcgattgcag ataacccctt tgcagctctg ggagggcttt ttgactagca gcgctagtca
    45361 tttctctgaa aaagaaaaat gacctaaggt cagggcttgc ttgtgacctt gggtcatatt
    45421 ctataatgag gacagaaagg aggtgaagga catgtctgat atttactcaa ctggtgagct
    45481 agcaaaagca gcaggtgtca ctgtcaggac agtgcaatat tacgataagc gtgggatttt
    45541 gttgccttcc cagcttactg aaggtggacg gcggatttac accgagtcag atttggagcg
    45601 attgaaaatc atttgcttct tacgggacct agatttttcc attgagcaga ttaagcgcgt
    45661 gctagcagaa gacaatgtta tggcggtgct tgacctcttg ctggtggatc atatccaaca
    45721 gctggaacaa gacttaagga caaaaaagca tcagcttgac acagctgtca agcttttgtc
    45781 aggtattcgc tgctcatcta gtcactctat caaaaaccta tcagacatgt cacttaccat
    45841 gaacaatcaa aaagcttggc gtcgtttgca gttgaaaatg tttagtaata ttgccctagc
    45901 aatattggtt catgtgatgt tagtgttact aactagctat tttcatctat cttggttggt
    45961 atggatagag gctccactat ggataatctt ttttacttta ttgatcgttt attttcgtaa
    46021 acaatttgag tacctatgtc caaattgtca tactattttt gaaccagact ttaaagagtt
    46081 tgccttggca ggtcacacac caaggacccg caggctgacc tgtcctcatt gccatcaaaa
    46141 atcttactgc cttgaattgg ccaaggaaaa ataatggaaa atctccgctg gatacccagt
    46201 ggagatttct tgctattaga atggtagctt gccagcaaag gctcctagag ttttcttagt
    46261 cgcctcatca atttgagcga gggctgcatt gatggcctga gcagtcatat cctgaagtgt
    46321 ctctatatcc tctgggtcaa cgactgcttc cttgaaatca atgctaacca attgcttatc
    46381 acctgtaaag gttgcagtga ccagctcctg agctgacttt cctgtaaatt gcatagctgc
    46441 taggtcagcc tgcttttgtt ccatttgctt ttgaagcttt tgcgcttgct tcatcatgtt
    46501 ttgcatgttc atcataagtt ccaattctcc taagttttga tacttaacta ttataacata
    46561 tcagacaaga cttcaaacat gtgatctttt aaagttaatg aaaaggccct gctagcctgc
    46621 aatgctttga tgtgctagcg actaacgaac aggtcgtttc ctttaaatag agttttcttg
    46681 ttgagcttta tagctggtgc ttgtttttgt gatgagcttg tgtgaggctg tcgttagtgt
    46741 tgttttaggt ggtttgacat caggagcgat taaaaaagtt atcagtttac atttttataa
    46801 taataactta agaattaatt taactttaga ttaatcttac tttatatttg attgctatac
    46861 ttagtccata acataaataa ccaaaaagaa agaggtaatc gttatgacaa caatgactac
    46921 aacaaaacaa tcaaagacaa ctctagcagc tcgttatttg aagcttggtc ttacttcagc
    46981 aatgtttgct ggaggagcct ttctagctct aggctcagca ccggctgtct ctgcttctac
    47041 ccatgctggt aatgatcagc cagcgactca acgcttaact gatcaggaga tctacgaacg
    47101 tgctcaaaag ctagacttgc cagactatgt gagaggctca atctacggta ttctcaacca
    47161 aaactcaagt gttacttatc caaaggatat agcaggtcta gagcagtcag aagctccaca
    47221 accccctgca gctccacagc tcactgacca agatgctcaa aagctggact tgccagacta
    47281 tgtgagaggc tcaatctacg gtattctcaa ccaaaattca agtgttactt atccaaagga
    47341 tatagccggt ttagagcagt cagaggctcc acaaccccct gcagctccac agctcactga
    47401 ccaagatgct caacagctag acttgccaga ctatgtgaga ggctcaatct acggtattct
    47461 caatcaaaac tcaagcatta cttatccgcg cgattattaa gcatctaaga tgattaaggt
    47521 gcacaatcga cgattaaaat gattgatgag ttaatgagat tagaattatt tggctaagtt
    47581 aagaattagt gttatacttg agagagtgta gcactaattt tttaatcaag gaggaagcat
    47641 gacctacaag atattattgg tggatgatga attggaaatt attgatatta acgaacgtta
    47701 tttgcaacag gcagggtatc gtgttaccac tgcaagcgat ggtagtcaag ccttggagct
    47761 ttttcataag gatcagtacg atttgattat cagtgatgtt atgatgccca atatggatgg
    47821 ctatgatttt attggggagg ttttactgga aaagccagat cagccctttc tctttatcac
    47881 tgcaaaaaca tctgagcctg acaagattta ttccttgagc ttgggagcag atgattttat
    47941 ttccaagccc tttagtccac gtgaattagt cttacgggtc aaaaatattt tgaatcggat
    48001 ttatggtaag gctaaccaag ctgactcctt agttattggg gatttggtca tggatcacag
    48061 cactcgaagg gttacagtgg caaatcaaga tctgaatctg accaacaagg cttttgattt
    48121 gttgtggatt ttggccaatc atttgaatca tgtcttttca aaaacagagc tttatgagcg
    48181 t
//
LOCUS       DARYXZ010000012        47121 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYXZ010000012 DARYXZ010000000
VERSION     DARYXZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47121
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            527..742
                     /locus_tag="TV186_000588"
     CDS             527..742
                     /locus_tag="TV186_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1532009.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            739..1515
                     /locus_tag="TV186_000589"
     CDS             739..1515
                     /locus_tag="TV186_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL1532010.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVMGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(1584..2840)
                     /locus_tag="TV186_000590"
     CDS             complement(1584..2840)
                     /locus_tag="TV186_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1532011.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(2926..3885)
                     /gene="nrdF"
                     /locus_tag="TV186_000591"
     CDS             complement(2926..3885)
                     /gene="nrdF"
                     /locus_tag="TV186_000591"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1532012.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(4030..6189)
                     /gene="nrdE"
                     /locus_tag="TV186_000592"
     CDS             complement(4030..6189)
                     /gene="nrdE"
                     /locus_tag="TV186_000592"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1532013.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(6210..6428)
                     /gene="nrdH"
                     /locus_tag="TV186_000593"
     CDS             complement(6210..6428)
                     /gene="nrdH"
                     /locus_tag="TV186_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL1532014.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            6850..7113
                     /locus_tag="TV186_000594"
     CDS             6850..7113
                     /locus_tag="TV186_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL1532015.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            7118..8851
                     /gene="ptsP"
                     /locus_tag="TV186_000595"
     CDS             7118..8851
                     /gene="ptsP"
                     /locus_tag="TV186_000595"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL1532016.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            9053..10480
                     /locus_tag="TV186_000596"
     CDS             9053..10480
                     /locus_tag="TV186_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1532017.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            11133..12347
                     /locus_tag="TV186_000597"
     CDS             11133..12347
                     /locus_tag="TV186_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1532018.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            12443..13012
                     /locus_tag="TV186_000598"
     CDS             12443..13012
                     /locus_tag="TV186_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1532019.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            13013..14965
                     /gene="gyrB"
                     /locus_tag="TV186_000599"
     CDS             13013..14965
                     /gene="gyrB"
                     /locus_tag="TV186_000599"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL1532020.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            15114..16838
                     /gene="ezrA"
                     /locus_tag="TV186_000600"
     CDS             15114..16838
                     /gene="ezrA"
                     /locus_tag="TV186_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL1532021.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            17210..17491
                     /locus_tag="TV186_000601"
     CDS             17210..17491
                     /locus_tag="TV186_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532022.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(17676..18131)
                     /locus_tag="TV186_000602"
     CDS             complement(17676..18131)
                     /locus_tag="TV186_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL1532023.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            18362..19669
                     /gene="eno"
                     /locus_tag="TV186_000603"
     CDS             18362..19669
                     /gene="eno"
                     /locus_tag="TV186_000603"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL1532024.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(19805..20041)
                     /locus_tag="TV186_000604"
                     /pseudo
     CDS             complement(19805..20041)
                     /locus_tag="TV186_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20250..20471
                     /locus_tag="TV186_000605"
     CDS             20250..20471
                     /locus_tag="TV186_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL1532025.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            20473..20733
                     /locus_tag="TV186_000606"
     CDS             20473..20733
                     /locus_tag="TV186_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1532026.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
     gene            21386..21991
                     /locus_tag="TV186_000607"
     CDS             21386..21991
                     /locus_tag="TV186_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1532027.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            22459..25239
                     /locus_tag="TV186_000608"
     CDS             22459..25239
                     /locus_tag="TV186_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1532028.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYLDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(25661..25798)
                     /locus_tag="TV186_000609"
     CDS             complement(25661..25798)
                     /locus_tag="TV186_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1532029.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      26042..26160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            26158..26664
                     /locus_tag="TV186_000610"
     CDS             26158..26664
                     /locus_tag="TV186_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL1532030.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            26761..28719
                     /gene="ligA"
                     /locus_tag="TV186_000611"
     CDS             26761..28719
                     /gene="ligA"
                     /locus_tag="TV186_000611"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL1532031.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            28732..29754
                     /locus_tag="TV186_000612"
     CDS             28732..29754
                     /locus_tag="TV186_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1532032.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            29763..32063
                     /gene="pulA"
                     /locus_tag="TV186_000613"
     CDS             29763..32063
                     /gene="pulA"
                     /locus_tag="TV186_000613"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL1532033.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            32210..34089
                     /gene="glgB"
                     /locus_tag="TV186_000614"
                     /pseudo
     CDS             32210..34089
                     /gene="glgB"
                     /locus_tag="TV186_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            34156..35295
                     /locus_tag="TV186_000615"
     CDS             34156..35295
                     /locus_tag="TV186_000615"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL1532034.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            35285..36418
                     /gene="glgD"
                     /locus_tag="TV186_000616"
     CDS             35285..36418
                     /gene="glgD"
                     /locus_tag="TV186_000616"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL1532035.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            36415..37845
                     /gene="glgA"
                     /locus_tag="TV186_000617"
     CDS             36415..37845
                     /gene="glgA"
                     /locus_tag="TV186_000617"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL1532036.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            37864..40260
                     /locus_tag="TV186_000618"
     CDS             37864..40260
                     /locus_tag="TV186_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL1532037.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            40602..40799
                     /locus_tag="TV186_000619"
     CDS             40602..40799
                     /locus_tag="TV186_000619"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL1532038.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            40833..41549
                     /gene="atpB"
                     /locus_tag="TV186_000620"
     CDS             40833..41549
                     /gene="atpB"
                     /locus_tag="TV186_000620"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL1532039.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            41567..42061
                     /gene="atpF"
                     /locus_tag="TV186_000621"
     CDS             41567..42061
                     /gene="atpF"
                     /locus_tag="TV186_000621"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL1532040.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            42061..42597
                     /locus_tag="TV186_000622"
     CDS             42061..42597
                     /locus_tag="TV186_000622"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL1532041.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            42613..44118
                     /locus_tag="TV186_000623"
     CDS             42613..44118
                     /locus_tag="TV186_000623"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL1532042.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            44136..45011
                     /locus_tag="TV186_000624"
     CDS             44136..45011
                     /locus_tag="TV186_000624"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL1532043.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            45179..46585
                     /gene="atpD"
                     /locus_tag="TV186_000625"
     CDS             45179..46585
                     /gene="atpD"
                     /locus_tag="TV186_000625"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL1532044.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            46598..47014
                     /locus_tag="TV186_000626"
     CDS             46598..47014
                     /locus_tag="TV186_000626"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL1532045.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT        13395 a         8970 c        11054 g        13702 t
ORIGIN      
        1 tatctttatt tttaattcaa aaatataagc aattgattca cataaacaaa ttgagacgaa
       61 cagtagattg tagctatatc acaggtgaga tagtaatgat cgtgcgaaac aataaactga
      121 tttttccatg cgggatattt gttatcagtg agttgaatgg aactagcagc tattgtttta
      181 ttgttagtca tctagtgttt ttaaggtgct tattttctgt tacaacagtg atgacaacag
      241 gttaagctaa gttcgatgga gcttggtttt ttattgttac aagaaagctc atagatggtg
      301 attgcattct tttatcatat gacaatgttt ctatttttga caaatattat tgtcaaaaag
      361 taaatgatct gttacactgg agttggactc atgaaagaaa aaagtaatca gtaggataac
      421 aataacaaag ctattttaag cttataccat tgtgtcaatg gattgttgcc ggaaatgact
      481 ggtgctttct gttcaatcag gagacagcat ttattaggag tgaagcatgg cttataggtt
      541 gagaaatcgg ctcaaggagc tacgagctag agatggcatt aatcagacgc agatggcagc
      601 attagcaggt gtttccaggc agaccattag cctcattgag cgaaatgaat acacaccatc
      661 tattattatt gcaatgaaaa ttgctaaagt atttaatgaa ccaattgaac aagtatttag
      721 cttagtggag ggcgagagat gaaagctttt atgacggaaa aggacagtac gttggtgaga
      781 atacttaagt cattactgct tggatcaggg attggcttag tgttaggtgg ccttgttggt
      841 tttggtttag ctaggtttaa catattagaa aatggctttc cgatatcaga agaagacacc
      901 ataactggaa taaagtgggg aatgagaccc cttgttatcg tgcttatgct gctgagcatt
      961 tatgatattt atcaagttgt caaagaatat gctagatatg tcaagctaag cgatgatgaa
     1021 acagaggagc tgtaccgtta cattaatctt aagcatgcct atgctttagg atttagcgct
     1081 atggctatgg tcttgaatat agtcgttttt tctttgggat atagggtgcc tattgctaat
     1141 aatgctagct atcttggttt gacttttcct atttacgagg ctctgatgct tgtggttatt
     1201 agtgttctcc atgcttatat tttgaaggtt tatactcgga ttcgcggggt caagatgacg
     1261 cttgctccta ccttaaagga attaaagcag aatatcttac aacaggacga ggcagaattg
     1321 caggctaatt atcaaatgtc ttttgaggtt gtcatgggcc ttagtggctt tatattacca
     1381 ggcatttacg taatattatt gcttttatct atgatttttc aaagggttga gctgaccgga
     1441 ctaatcatta ctgctagtat tcacctctat attctggtga aatcctttaa atcagcacat
     1501 gatttttata ggtaaggcgt aaggttttac ctactcaaga attgttatac agcaaaaaag
     1561 ctttgataag ccattactgg cgatcaaagc tttttgtgtt tgttgaaaaa gaggcttttt
     1621 tgaaagagct gttggctgag atagcttgtc aaacctacaa ttgcaagcgg cacaaggcta
     1681 atgagaggtt gtccggtaat ttcaatgaga aaaagaggag cagtaagagg tatctgatta
     1741 atgattccca aaaagagggt cgctccaatg acaatggcca agggaagtgg tacagagaga
     1801 taacctagct gattgctaag gcttgccagt agcaagccac tagctcctcc aagcatcata
     1861 gaaggagcaa ttttgcctcc tttagctcca gaggcaaata ctgcatagac agcagctgct
     1921 ttacttagta agagcgaggc ggtataagat aggctgacat catggtgtag cagcaggagg
     1981 agaccggcct tgccattgcc taaaatctct gggaaataaa ggcttaaaca agcactaaag
     2041 ccaaaagccc ctaagacacg agggataaac catcggctct taggctttgc ctttggtgcg
     2101 ttttggagca gctgctggta gcaaaaggcc agaaatgcta agatgggact ggcaatgata
     2161 gcccaaagga ctgttgtcag ttgccaggct tgtgggagaa tgagatactg tatgtcctga
     2221 tgtccgctta gaacaagcac actttgaaca gcagtaaagg cagttatagc tgccgcgtaa
     2281 atgtgtttaa ctgagcattt tttgacaata gcctccatga taaagacaat cgtagctaat
     2341 ggtgcctggt aaacagctcc aagggcagct cctgaagcac aggctaaaag caatccttgc
     2401 tctgctgctg atgcgtttat agctttattg caagcggcag tcagtgccac agcaacctca
     2461 cgtgaagcac cttcacgacc gacaggtgct cccatggaga cggttattaa ttgcagccag
     2521 ccatgacaaa attgtgtcca agggctgaaa tccttttgct gactgagtgt ttgttggata
     2581 ggctgaatag gcttggcttt tttagcaagt agctgccagc cgagaccagc aatagctcca
     2641 gccaacaata gagataaaaa acgcctttct ggagctaccg ttgcaatcat ggtgctaaaa
     2701 gacccagatt ggtatccaaa gctaatagcc tgtatgaaat gaatggcttg agtgagcacg
     2761 taagccacca caccagcaat cacaccagct accaccagtt ggcccgtcca tgttaagaaa
     2821 gtaatcaatc gagtaatcat atcttttatt atagcagata aaaagagcct gagactactc
     2881 aggctccaaa atatagataa atccaatctt catgagaagc tggacttata gcccataatt
     2941 gtaatcgtca tcagtcatag cttcaacagt accaagaagg tagccattac caacttgaga
     3001 gaagaaatcg tggtttgacg tgccggttga aataccattc ataacgattg ggttgacatc
     3061 attggcagtg tctggaaaaa gagggtcctg accaaggttc atcaaagcct tgttagcgtt
     3121 gtagcgtagg aaggtcatca cttcctcggt ccagccaacc tcatcataga gggtcttggt
     3181 gtattgctct tcattttcat atagctgata cagcaggtca tacatccagt cacgaaggct
     3241 ttcttgctca ctctctgata gctcattaaa gcccagctga aacttgtagc cgatataagt
     3301 gccatgaacg gactcatcac gaatgatgag cttaataatt tcagcgacat tagccagctt
     3361 attgttgccc agataataga gtggtgtaaa aaagccagaa taaaatagaa aggtttcgag
     3421 ataagtcgag gctacctttt tttgaagggc actgccattt tcataaatgt cgttgattat
     3481 cttagcctta ttttgaagaa atacgttgtt gttggtccac tcaaaaatgt cttcaatttc
     3541 ttttttggtg tttagggtcg aaaagattga tgagtaggat ttagcatgga cagactccat
     3601 aaattggata ttgttaagaa ctgcctcttc atgcggggtg cgcacgtcct tgcgaatggc
     3661 ttcgactcct gactcagact gcatcgtatc aagaagggtt agcccgccaa agaccttacc
     3721 tactaaatcc ttttcaacag cagataatct gcgccagtca tcaaggtcat ttgatagtgg
     3781 aatacgtgta tcaagccaga attgctccgt cagcttttcc caggttgact tgtcaatgac
     3841 atcttcgatt tcattccagt tgattgcttc atagtatgtg gtcatgagtt tctccggtag
     3901 attgtaatat agggttaggt atgctaggag gagagccttg agtgctggtc tatcattagg
     3961 acaggtgcac tgacacatca gctaggctct gacattaagg actggtccac ctcactgcca
     4021 ttcacttggt tagatgacac agctttcaca ctgattggct ccgacctcct cgccatcatc
     4081 ggtaaaggtg cggatataat agattgattt tatcccttta ttaaaggcgt aatgtctcaa
     4141 aatagatagg tcacgagtgg tttgcttgct ttctgttttc cattcgtaga gctcctttgg
     4201 caattcgctg cgcaaaaaga gtgttaacga cagtccctga tcaacatgct ttgtagcagc
     4261 tgcatagaca tcaatcacct ttctcatgtc catatcatag gcagatgtgt agtaaggaat
     4321 ggtgtctgta gataggccgt tggctgggta ataaatcttg ccgattttct tttcctgacg
     4381 ttcttcgatc cgctgagtaa tcgggtgaat agaagcagag cagtcgttga tataggaaat
     4441 tgatccatta ggagcaactg ccagacggtt ttggtgataa aggccatctg tcataatcgc
     4501 ttgacgcagc gccttccagt ctgctgcttg cggaataaag tgatccttga aaaggctttt
     4561 aaccagctct gattttggca cacattctcc tgtgatgtac tggtcaaaat aagcaccgct
     4621 agcatatgtt gatttttcaa agccaacaaa ggttgtctga cgctcgcgag cgatctgatt
     4681 ggattcgaca agcgtccagt aattcatcag cataaagtaa atatcagtaa attcgataga
     4741 ttctgggctg ccatattcga tatggtgctg agccaaatag gaatgaagcc ccatagcccc
     4801 aaggccaaag gtatgtgctt gactgttacc atttttaaca gttgggactg cttcgatatt
     4861 agaggagtca gtgacaaagg tcagggcacg tgtcatggct ctgatggaac gaccaaagtc
     4921 aggtgacgtc atcatgttta agatattagt tgatcccaga ttgcaggaaa tatcagttcc
     4981 cattttgaca aactcctgcg catcattaat gagactaggc gtttgaacct gtagaatttc
     5041 tgagcatagg ttgctcatga tgattttacc gtcaataggg tttgacctgt tggcagtgtc
     5101 gatgttgata acatagggat agccagattc ctgctggagc ttggaaatct ctgtctccaa
     5161 atcacgtgct ttgatttttg ttttggtgat attaggattg gcaaccaatt cgtcatacat
     5221 gctagtaata tcaatgtagt taaatggcag gccgtattct ctttcaacac tataagggct
     5281 aaagagatac atgtcagcat tgtgacgagc aagctcataa aacttatctg gtacagtaat
     5341 accaagtgac aatgtcttga cccgcacctt ttcatctgca ttttcttttt tggtagacaa
     5401 aaaagcgata atatcagggt gaaagacgct taaatacacc acaccagccc cttgacgctg
     5461 ccctagctgg ttggaataag aaaagctgtc ctcaaatagc ttcattacag gcacaacacc
     5521 agaagcagct ccggcatagc ccttgattgg agcgccagcc tcacgaaggt tggataggct
     5581 aatgccaaca ccacccccaa tacgggataa ttgcaaggca gaattaatag agcggccaat
     5641 ggcattcata tcatctgtca cctgaaggag aaagcaagaa accagctcac cacgacggct
     5701 ccgtccagca tttaaaaaag aaggagtagc aggttggtaa cgctgattaa tcatctcaat
     5761 ggctaagtcc ttagctaatg tttcatcacc atcagcaaaa taaagggcat tgaacatgac
     5821 ccgatcctct atgctctcta agtagaaatt gccatcattg gtttttaggg catactgctg
     5881 ataaaattta taggccgcca taaatgattt aaagcgaaag ccctctgctt gaatgctctt
     5941 ggctagatgg ctgataaatt caggagaata gttttggata aaggctgatt caatatagtc
     6001 attgtctaca agataggcaa tcttttcgtt gatagaagaa aatgacatgg tgttaggaat
     6061 aacattttcg gtaaaaaaag cctccaaagc ttccttgtct ttatgaagtg gaatgctgcc
     6121 atcaacagga cggttaattt cattgttgag gcgaaagtaa gaaatatcgc caagatcttt
     6181 gagactcata tcaattgttc cttgtctagt taaataatat cttttaattt tgctggctga
     6241 aaccctgaga atactatctg ctctgtctca ataacaggag cagcagtaaa gccaaggctc
     6301 ttaacatagt ccactttttc tggatgctca tcaatattaa tctcttggaa agcagctcca
     6361 tgctgttcta aaaatttctt agtcattttg cactgcatgc aattgtgctt tgagtatact
     6421 gtaatcattg ctcgtccttc caactattag tctttcactc aattttagga aaaatcaaat
     6481 gactctaata ggatataaaa aatgttccta aaaagcaaac gatttatttc agaatagcac
     6541 aagatattgt ggttgtgtgt gagaatattt ctaaatattg tgttatcctc tcttatcact
     6601 gataattgct acaagaggct tgtagttctt aaatgcatac taatcaggtt ggaaggctta
     6661 tttgacatta tgaaaatcat catgtaagaa atattgacaa caaatgaaaa tacaagaaaa
     6721 ctgtttcatg attttttctt gttagaacat ttaaccttga aaataaaaaa gcattgtgct
     6781 ataatcactt attgtaaggg ttatcatgtg atagctcgaa aatacacaat tcaaaaggag
     6841 aaccatatta tggcttcaaa agactttcac attgttgcag aaacaggtat tcatgcacgc
     6901 ccagctacct tacttattca aacagcaagc aaatttgctt cagatattac acttgactac
     6961 aaaggtaaag cagtaaatct taaatcaatc atgggtgtta tgagccttgg tgttggtcaa
     7021 ggtgctgacg taacaatcac agcagaaggc gctgatgcag atgacgctat tgcggcaatc
     7081 gaagaaacta tgactaaaga aggattggca taagactatg acagaaatgc ttaaaggaat
     7141 cgcagcctct gacggtgttg ctgttgccaa agcatatctg ctagttcagc cggatttgtc
     7201 atttgagact atcacagtcg aggatacaaa tgcagaagaa gctcgccttg atgttgcact
     7261 acaagcttca caagacgagc tttctgttat ccgagaaaaa gcagtagaaa gcctaggcga
     7321 agaagcggca gcagtttttg atgcccattt aatggttctt gctgatccag agatgatcag
     7381 ccaaattaaa gagactattc gtgcgaagca aacgaatgct gaaacaggtc taaaagaagt
     7441 gactgacatg ttcatcacaa tctttgaagg catggaagac aatccttata tgcaagagcg
     7501 tgcggctgat attcgagatg tcgctaagcg cgtcttggct catttattag gtgttaagct
     7561 tccaaatcca gctacaattg atgaagaagc aattgttatt gcacatgatt tgactccttc
     7621 agatactgca cagcttaaca aacaatttgt aaaagcattt gtaacgaaca ttggcggacg
     7681 tacgagtcat tcggctatca tggcccgtac acttgagatt gcggctgtgc ttggtacaaa
     7741 tgatattact aagcgtgtca aagatggtga ccttattgct gttaatggta tcactggtga
     7801 ggttattatt gacccaagtg aggagcagat tcttgctttc aaggaagctg gagaggctta
     7861 tgcgaagcaa aaggctgagt gggctctgct taaggacgca caaactgtca cagcagatgg
     7921 caagtacttt gaattagcag caaacatcgg tacacctaag gacgttgaag gtgtcaacga
     7981 taatggtgct gaggcggtag gtctttaccg tactgagttt ctttatatgg attctcagga
     8041 tttcccaacc gaagatgagc aatatgaagc ctacaaggct gttcttgaag gaatgaacgg
     8101 caagcctgtt gttgttcgta caatggatat cggtggggac aaggagcttc cttactttga
     8161 tttaccaaag gaaatgaacc cattccttgg ttttcgtgcc ttacgcattt caatctctga
     8221 aacaggtaat gctatgttcc gcacacaaat tcgtgctttg ctgcgtgctt ctgtgcatgg
     8281 tcaattgcgt atcatgttcc cgatggttgc ccttctaaag gaatttcgtg ctgctaaagt
     8341 cgtatttgaa gaagaaaagg ctagcttgct gtctgagggt gttgcggttg cagacgatat
     8401 tcaggttggt atcatgattg agatcccagc agcagcaatg cttgctgacc aatttgccaa
     8461 ggaggttgac ttcttctcaa ttggtacaaa tgaccttatc cagtacacaa tggcagcaga
     8521 ccgcatgaac gagcaagtgt cataccttta ccagccatat aacccatcaa tccttcgttt
     8581 gattaacaat gttatcaaag cagctcatgc tgaaggtaag tgggctggta tgtgtggtga
     8641 aatggcaggt gaccaacagg ctgtgccgct tcttgttggt atggggcttg atgaattttc
     8701 aatgtcagca acatctgtgc ttcgcacacg tagcctgatg aaaaagcttg attcagcgaa
     8761 aatggcagag tatgctcatc gtgcactcac agaatgctca actgctgaag aggttcttga
     8821 gcttgccaaa gagtatatta cagaagctta aatagaaata acgaggagct ggttttgtcc
     8881 ggctcttttt tactagaaaa atgactaatc agatccatat gaaagcttgc tttataaagt
     8941 agtttgatgt ttcaagtttt atcagaattt tcagactctt cctgtagcga attgttgaaa
     9001 tatgctaaaa aagtgataga ataatagtac cattataaaa ggagaaaaaa gtttggctaa
     9061 acaatataaa aatttagtga atggtgagtg gaagctctct gaaaatgaga tcaagatcta
     9121 tgcaccagca accggcgagg agttaggtag tgtaccagct atgtctcgtg aagaggttga
     9181 tcaggtttat gcgtcagctc gcgctgctct tgcagattgg agagcgcttt cttatgttga
     9241 gcgtactgct tatttgcaca aggctgctga tattttggtg cgtgatgctg agaagattgg
     9301 tgctgttctc tcaaaagagg ttgcaaaggg ttataaggct gctgttagtg aggttattcg
     9361 tacagcagaa attattaact atgcagcaga agaaggcctt cgtatggaag gcgaggtcct
     9421 tgagggtggc agctttgagg ctgctagtaa gaaaaagatt gcgatcgtac gtcgtgagcc
     9481 agtgggactt gtgcttgcga tttcaccctt caattatccg attaacctag caggctcaaa
     9541 gattgctcca gcccttattg caggaaatgt cgtggttctt aagccgccga cacaaggctc
     9601 tatttctggc ttgctcttag cagaggtatt tgcagaagca ggtcttcctg ctggagtctt
     9661 taataccatc actggacgcg gctcagttat tggtgattac atcgttgagc atgaggctgt
     9721 aaactttatc aactttactg gctcaacgcc aattggagag cgaattggta aattagccgg
     9781 catgcgtccg attatgcttg agcttggtgg taaggattca gcgattgtct tagaagatgc
     9841 tgatattgcc ttagctgcta aaaacattgt tgcaggtgcc tttggctact caggtcaacg
     9901 ctgtacagca gttaagcgtg tgcttgttat ggaaagcgtt gcagaccagc tggtagcaga
     9961 gattaagggc ttagttgaga aattacttat cggtatgcca gaggacaatg ctgacatcac
    10021 accattgatt gataccaaag cggcagattt tgttgaaggt ctggttaatg atgcagcaga
    10081 caagggagca caggcgctta ctgaaatcaa gcgtgacggt aatttaattt gtcctatctt
    10141 gtttgataga gtaacaactg atatgcgctt ggcttgggag gagccatttg gtccggtgct
    10201 gccagtgatt cgtgtaagct ctgtagaaga ggcaatcagc atttcaaatc aatctgaata
    10261 cggtttgcaa gcgtctatct ttacgactaa ttttccacag gcctttgcta ttgctgagaa
    10321 gcttgaggtt ggtacagtac acattaacaa caaaacccaa cgtggtacag ataatttccc
    10381 attcctaggg gctaagaaat caggagctgg tgttcaaggg gtcaaatatt caattgaggc
    10441 aatgacaagt ctcaaatcag tcgtatttga tattcaataa caaaaaagct agggtatctt
    10501 agtttgaaag cagttgcaca tttgtgcggc tgttttattt gtgtctctag ttttaacagc
    10561 tagctatgca agaaggtgag ttgtcccaac ctcaaagatg agatctaaat atttaatgat
    10621 tttggggtcg taaaaaagtt tagagtgttt tgatctcctt aagatgtgag tgtacaaagt
    10681 ctcgccaaca gccagcagga ctagccattg aggtcaagga agctgctaaa atagctgatg
    10741 gttcaaaagc ttggtgaaag gcttaatatc tatcattgct attttgaggg ctttccatta
    10801 taatatgaat actagagcta cttgtcggtc tgcctcttga gctgtgagat agctgttgga
    10861 tttagttgtc tccttgtcca caaaaggctt agaggcaaag gctgtggcta tgcttcttgc
    10921 ttcttttagt gaagtgtatg agatcttatg aaaactcata taggctttgg tatctttgca
    10981 agaggactaa tggcttgctt tacttgcctt gatagagggc tgggattgag gggtgatgac
    11041 ctgcggtggt catctctaga gctccttgct tcttttttta tgtagactaa tggtttagac
    11101 tgctagcttc cttgtttaga aagtaggaca tcatgttacc caagagaaaa ttaattgatc
    11161 aacgtcttga ttatgccatt atttttcctg ttttttgttt gctaatattt ggtctggtat
    11221 ctgtatatgt ggcagcaagt catgattttc cgcaaagcct cgccactgtt atgcttcaac
    11281 aggttctctg gatccttctt ggagctgtga ttgcctttac cctaatgttt tttagcacag
    11341 agattctgtg gaaattaaca cctgtctttt atcttttggg tgtgctatta atggttctgc
    11401 cactcatctt ttttagccct cggctggtag ctgctacagg ggcgaaaaat tggattacga
    11461 ttggctcaac gaccttgttt caaccatcag aatttatgaa aatatcctac attctggcaa
    11521 tgtcttggtt aacggtctgg tttaagagaa agcaggagag aagtcggttt ttagatgatt
    11581 ggaagctctt gggcttatac cttgtcttga cgttgccggt catggtcctg ctagcactgc
    11641 aaaaggactt aggaacagct atggtttttt tagccatctt agctgggatt atcttaattt
    11701 caggaatttc ttggtggctt attttaccag ctttggtact agtcttttta ctggtttcag
    11761 cttttttctt tgtttttttg ttgccagagg gaaaagaatt ccttttaaaa atgggaatgg
    11821 atacctacca attgaatcgt atttcagctt ggctgacacc gtttgatttc tcagatacca
    11881 ttgcctatca gcagacgcaa agtatgattt cgattgggag tggtggcttt tttggtaagg
    11941 gctttaatca gcttgagctg tcagtaccag tcagagaaag tgatatgatt tttacagtga
    12001 tcgctgaaaa ttttggcttt cttggtgcag ctagcttact gatcttgtat ttaatactga
    12061 tttaccgcat gcttagggtg acctttgcat cgaataacct tttttatacc tacatttcaa
    12121 ccggctttat catgatgata ctatttcata tttttgaaaa cattggcgca gcagttggtc
    12181 tgctaccttt gaccggtatt ccccttccct ttatttctca gggcggctct tccttgattt
    12241 caaatctgat tggggtcggc ctgatcctat caatgaacta tcagcacgtc cttgctcatg
    12301 aaaagcaaag cgagcatgag cttagcagaa gctcacgtta tgtttaagag gcatgtttgg
    12361 tccttgttcg gttagaatga gctgccaatc agcccttttt tatttgctta atcgctataa
    12421 aaataaagaa aaatatgtta taattaaggt tatgaattat catgattata tttgggattt
    12481 gggcggcact ctcttggata actatgaaat ttctacccag gcttttattg agacgctgca
    12541 tttttttaag ctgtctgcaa gccacgatgc cgtttatcaa aggcttaaga aatcaacagc
    12601 aaccgccatt caagtatttg ctcccaacga accgcaattt ttacaatatt acaaagcgaa
    12661 tgaggctaag aaattagcca atcctatttg gtgcctaggt gcaaaggaca ttctaaagag
    12721 gattgtggca tcaggctcgc gtaatttttt aatatcccat cgtgatcatc aggtcaatga
    12781 tttgctggag caggctgggc ttttgggcta ttttaccgag gttgttaccg cctcaaatgg
    12841 ctttgccaga aagcctaacc ctgagagctt actttatttg aaggaaaagt acctgatcag
    12901 caagggctta gtgattggtg atcgcagact tgatatagaa gcaggacaag cagcaggctt
    12961 tgacaccctg cttgttgatg gtagaaaaaa cctattggag atagtagatt agatggttga
    13021 agaaaataaa caattagaag acaaggctca agagtatgac gctagccaga ttcaggtctt
    13081 agaggggtta gaagccgttc gcatgcgtcc tggaatgtat attggctcaa ctgccaagga
    13141 aggcttacat cacctagttt gggagattgt tgataattct atcgatgaag ccttggcagg
    13201 ctttgccagt catattcagg tttttattga ggcagataat tcgattaccg ttattgatga
    13261 tggacgtggt atcccagttg atattcaagc taagacaggc cggcctgctg tagagacagt
    13321 ttttacagtt ttgcatgccg gtggaaaatt tggcggtggt ggctacaagg tttctggagg
    13381 acttcatggt gttggctcct cggttgttaa tgccttatcc acacagcttg atgttcgtgt
    13441 ctataaaaat gggcatatcc actatcagga gtttaggcgt ggtgctgtag ttgatgattt
    13501 ggctatcatt ggaacgactg atgttacggg aacaacagtg catttcacac ctgatccaga
    13561 gatctttaca gaaacaacag aatttgacta ccaggtcctg gcaaagcgta ttcaagagct
    13621 ggcctttctt aatcgtggct taaaaatctc aattacagat aaacgagctg gtcttgaaag
    13681 agaagagcat ttccattacg agggtggtat tggctcttat gttgcctttt taaatgacaa
    13741 aaaggacgtc atcttcgata ctccgattta ttctgatggt gagctggagg ggataacagt
    13801 tgaggtggcg atgcagtaca ctacaggtta ccatgagact gttatgagct ttgccaacaa
    13861 tattcacaca catgagggtg gtacccatga gcagggcttt agaacagctc tgacgcgcgt
    13921 gattaatgac tatgctaaga aggctaagat tctcaaggaa aacgaggata atctgacagg
    13981 tgaggacgtc cgcgagggct tgactgctgt tatttctgtc aagcacccaa atccacaatt
    14041 tgaagggcaa acaaagacaa agttaggaaa ttctgaggtt gttaagatta ccaatcgctt
    14101 gtttagcgaa gctcttcagc gctttctact agagaatccg caggttgccc gtaagattgt
    14161 tgaaaagggg attctagcct ctaaggctcg cattgctgcc aagagagcgc gtgaagtaac
    14221 ccgcaaaaaa tcaggcctag agatttccaa tttgccaggg aagctggctg actgctcctc
    14281 aaatgatgct agtcaaaatg agctttttat cgtggagggg gattcggctg gtggatcagc
    14341 gaagtcaggt cgcaatcgtg agtttcaggc tattctgcct attcgtggta aaattttaaa
    14401 cgttgaaaaa gcaacgatgg ataaaatcct tgctaacgaa gaaatcagaa gcctctttac
    14461 tgctatgggg acaggctttg gagcggagtt tgatgtttct agagctcgct atcaaaagct
    14521 ggtcatcatg actgatgcag atgtcgatgg agctcatatc agaacgcttt tgttaacgtt
    14581 gatttatcgc ttcatgcgac cagtattaga ggctggctat gtttacattg ctcagccacc
    14641 gatttatggt gttaaggttg gcagcgagat taaggaatac attcaaccgg gagtcaacca
    14701 agaagaggag ctaaaggctg ctcttgaaag acatagcaca ggacgctcaa ggccgactat
    14761 tcaacgctat aagggcctag gagagatgga cgatcaccag ctttgggaaa caacaatgga
    14821 ccctgataat cgtctaatgg cacgtgtgac cgtagatgat gcggcagagg ctgatcggat
    14881 ttttgacatg ctgatgggcg atcgtgttga gccaaggcgt gaatttattg aggaaaatgc
    14941 ggtctatagt acgcttgaca tttagtcaaa tatattttga aaagcaccta aaagtatgtt
    15001 ataatcgtaa cgttatagtg tatttttgat aatataataa aaggcgattc ttgctagttg
    15061 ttcctactga accggcagtt gatcaatcgc atctaaataa taaggagatt aagatgtcaa
    15121 gcggaattat cttgctgatt gtggccatag tcttactagt gattattgct tatttagtgg
    15181 gtgttattat acgcaagcgt aatgacacat taattaccag tctagaagaa cgaaaacaag
    15241 ctttatttgg ccttcctgtt aatgacgaaa tcgaggaagt caagtctctt cacttgattg
    15301 gtcaaagcca gacctcattt cgtgaatgga atcaaaagtg ggttgatttg accctaaata
    15361 cctttaccga tattgaaaag catatctttg aggctgagca cttaaatgac acctttaatt
    15421 tcattcgtgc caagcatgag attaatagcg ttgagagtca attgaatctc gttgaagagg
    15481 atattaccgc tattcgtgaa gcacttggca tattaaagga gcaggaagaa aaaaacagcg
    15541 cgcgtgttac tcatgcacta gatttgtacg aaaagttgca ggcttccgtt gctgaaaatg
    15601 aagataattt cggatcaaca atggccgaaa ttgaaaagca aatgaagaat attgaagcag
    15661 agttttcaca atttgttgcc cttaattcat caggtgaccc tgttgaagca gcggaggttt
    15721 tggataaggc tgaggagcat acgattgcct tggggcaaat tacagagcag atccctgcta
    15781 ttgtagcaaa gcttgaagat gattttccgg atcaattgga cgatctggag acaggctatc
    15841 gtcgtttgct ggaggaaaat tatcacttcc cagaaaaaaa tattgaagcc cgctttcaag
    15901 agattcgtga gtctattcgt gccaattcat cagagctggt tacccttgat ttggaccgag
    15961 ctagagatga aaatactcac attcaagagc gtatcgactc actgtatgag ctctttgagc
    16021 gtgagattgc agcctacaag gtggttgcta aaaatagcaa aatattacca agatacctgg
    16081 ctcacgccaa gcacaacaac gagcagttga agcatgagat tgctcgtcta tcacgtaagt
    16141 atatcttgag tgaaaatgaa ggcttaaata tcaaggcctt tgacaaagac ctcaaagata
    16201 tcgaagacaa tgtccttgag attgctgaag cctttgatca gcaggaaaag ccattttcag
    16261 agctacagct gattcttgat cgtagtatca agacgttggc ttctgtagag tctggtcaga
    16321 tggacgtctt tgctgctgtt aaagacattg aaaagattga gtcacaggct cgccagcact
    16381 tagaaatcta cgtcacacag cttcacatga ttaagcgtta tatggaaaag cgcaatttac
    16441 cgggaattcc acaggatttt ctgagtacct tctttaccac tagttcgcag ctagaagcat
    16501 tgatggacga actaagtaga ggacgtatca acattgaagc ggtgtcccgt ctgtctgagg
    16561 tggcaacagc tgctattgct aatctagaag agctaaccta ccaagtggtt cagcatgcta
    16621 ccttgacaga gcagctgctc cagtactcta accgttatcg ttcctttgaa gctggcgtgc
    16681 aaaatagctt tgagcatgcc ttgaaattgt tcgaggtgga caatgactat caggcatcat
    16741 ttgatgagat ttcctatgcc ttggagacag tcgagccagg agtgacagag cgttttgtca
    16801 attcctatga gaagacacgt gaacgtatcc gcttctaatg tgacaagggt tgatacttta
    16861 tattacgaaa aagcttgaaa aagcagtcca tgctgggcta tgctttttca agctttttga
    16921 atggtcaggc tatggcctcc ttgagctata cccaaaaagc tggttcaagc cagtcagtag
    16981 agatagacaa ggccttagtg ctattgggct gttgctacat gagatatttt gtaataaaat
    17041 cagacgatta tccatttaat taaaaaaaaa aaaaaaacga aactgcggag gaaacctgac
    17101 gagtaactat ttatggctat caatcagcat gttacactct ttttggaagg cctagcaatc
    17161 actgactgtg aggttaacca aagaaaataa gatgttaagg agaatatcaa tgaaaataac
    17221 taaagcattg tgtgtagcag gtgctgttgc agtcctagcc ttggcaccaa tcagctcaag
    17281 tcctgcacca acacagactg tatttgctgc tacacgtggt actgaagagt actgtcataa
    17341 tgggtggtgc agttttcttg atgaacatgg tgagtggaac acgaaacgtg agggcgaatc
    17401 taatagtccc ctacagcgag gttcatggtg ggattggatt tcttattggt ctggttatat
    17461 atggtattct gtatataact ggtttaggta acctctcaac gccactgcta ccatactgat
    17521 aaatccctta gactattcta agggattttt actgcaaaaa gcacataggg acaaggcaat
    17581 acaagctcca gcctgttctt agctccctat accggtaagg atcataacac tcagaactcc
    17641 ggcagatgat tgcaggagct attggagagt gaggactagt gaaagagcct ctgccagagg
    17701 gatttgccct tagtctttgt ttgttcagca ggcttattgt cagagggctt gtctagtata
    17761 gccttgagat tggtttcctc tttggtgatg gcatgatcac tatgaatgat cagagcaaaa
    17821 ggagagacag ctcctttctc atctacaata gtggcagata gagcgttttg ttgggccaat
    17881 ttcatatagt acatttgata agcagagccg aattcagagg ataatttgaa tgacaagggg
    17941 aaataagcct ctttgaggtg aggcagctgg gctgtgatgt agcctttagc cttttcatga
    18001 tcaacctctg tcaagggaag cgctaagaca atcctttcag cataggtccc taaataatag
    18061 cgttgttggt cggggtcaaa tcggttttct cctgaagctc cctttaagag tcttgtatct
    18121 aatgaatcca tacaatcctt tcaagcatgt gatactgtca ttatactatt aactgcgcca
    18181 aataccaatg ataaagcatt tactaggtat ttgatcggct tttggaagaa gatgaaatca
    18241 aagaaaaaca gcatgaaaac aactctctta tttcatgaaa ttagttttta agttgcttaa
    18301 gaccctagtt tgtggtatta ttaacatgta aaatattaaa actcataagg agagtattat
    18361 aatgtcaatt attactgatg tttacgctcg cgaagtcctt gactcacgcg gtaacccaac
    18421 acttgaagtg gaagtttata ctgaatcagg tgctttcgga cgtggtatgg ttccttcagg
    18481 agcttctact ggtgagcatg aagcagtaga acttcgtgat ggcgacaaat ctcgttacct
    18541 tggtcttggt actcaaaagg cagttgacaa cgttaacaac attatcgctg aagcgatcat
    18601 tggttatgat gttcgcgatc aacaagctat tgacagagcc atgatcgctc ttgacggtac
    18661 tccaaacaaa ggtaagcttg gtgctaatgc tattcttggt gtgtctatcg ctgtagcgcg
    18721 tgctgctgct gactaccttg aggtgccact ttacacttac cttggaggat tcaatactaa
    18781 ggttcttcca actcctatga tgaatattat caacggtggt tctcactcag acgctccaat
    18841 tgctttccaa gagttcatga ttatgccagt tggtgcacct accttcaaag aaggtcttcg
    18901 ttggggtgct gaggtattcc atgctcttaa gaaaatcctt aaagcgcgtg gacttgttac
    18961 tgctgttggt gacgaaggtg gatttgctcc taaatttgaa ggaactgaag atggtgtaga
    19021 aacaatcctt aaggctatcg aagctgctgg ctatgaagct ggtgaaaatg gtatcatgat
    19081 tggttttgac tgtgcgtcat cagaattcta cgataaagag cgcaaagtct acgactacac
    19141 taagtttgaa ggtgaaggcg ctgctgttcg tacatctgca gagcaaattg actaccttga
    19201 agaattggtt aacaaatacc caattatcac aatcgaagac ggtatggacg aaaatgactg
    19261 ggaaggctgg aaagcactta ctgagcgcct aggcaaacgt gttcaattgg ttggtgatga
    19321 cttcttcgtt acaaacactg aataccttgc tcgtggtatc aaagaaggtg cagctaactc
    19381 aatccttatc aaggttaacc aaatcggtac tttgactgaa acctttgaag ctatcgaaat
    19441 ggctaaggaa gctggctaca ctgctgttgt atcacaccgc tcaggtgaaa ctgaagattc
    19501 aacaatcgct gacatcgcag tggcaacaaa cgctggccaa atcaaaacag gttcattgtc
    19561 acgtactgac cgtatcgcta aatacaacca attgcttcgc atcgaagatc aacttggtga
    19621 agttgcacaa tacaaaggga tcaaatcatt ctacaacctt aaaaaataat ttgattttag
    19681 attaaaaggt tgacaagcct tgattttaaa gcattctagg actgtcctag agtgctttta
    19741 gttttagctt catgtcaact gtagtgggtg actgatagct aagcacgaga ggagacgaag
    19801 gtcgccttct ctttttcaat cggataaggc tagggaatcc ccaaatgtcg atgaagggaa
    19861 ttttagaagg tttctggaag tcgtatatga tttgtttccc tttgcagtgt ctacacctag
    19921 gagactgata gtccagtgta gcgctgactt cgatatgagt atcgtgctgg atagtcttat
    19981 tcaaggtgat attttgatct ttgattccga tgagtagtgt ggtatgatga atctgttcca
    20041 taagacactt tctaatgatg gtctggtcgc ttttcatgat aagccttatg gaactttttg
    20101 ggtactcaaa aagccctata atcttcataa tgaatttacc cattacagaa attatagagc
    20161 caatatttag aggattttag cctattggta gattgacagt ttcttaagat tgtgttacaa
    20221 tgtaacacaa agaaacgagg taaacgacta tgagtacagt tactatcaga ttaaatcaag
    20281 aagaagaaat atttttcaaa agttacgccc aactcacagg gcaaagttta tcaagtctat
    20341 ttaaaaaagc ccttgagcgg gatattgaag atgagtatga tttaaaaatc tatcatcaag
    20401 cctatgctga atataaagca gaccctgaga caattagcca tgctgatttt aagaaagagc
    20461 taggcttata acatgtaccg tatagagtat tctaaaaagg ctcaaaagca gattaagaaa
    20521 gtagataagc aaattcagag gttgctattt gcttggattg ataagtattt agagggaaca
    20581 gataacccac gcgcaaatgg caaaggtttg accggaaatc atgctaatga gtggcgttat
    20641 cgtattggtg attataggct tatttgtgat attcaagatg ataagatggt tgttttagcg
    20701 cttgagtttg ggcatcgtaa agatatttac taacgttgag gaagtaagat ggtcaaaaat
    20761 aatgcaattg gtagcaactg gaaagatgta agagctgagt tattcagcaa ggaagaattt
    20821 tagaaagtga tgctcgtatt gctattatgg acaagtatag ttaaaaagtg tgcgttttta
    20881 atctgtatga tgaagtaatt gataaagtaa caggtcaaaa ggctatcatt gtctgtattg
    20941 ctaataaatt ggtagatgat tgttatttaa tcgaaccgct aaaccattct tacttaccag
    21001 attggcgtga gataaatcag ttaattcgat ataaaaatta gcaccttatc gggtgctaat
    21061 tccttgcctg ctgaactcat aatttaatac cttttttact accccatatg tttcccctaa
    21121 ttatgtgtac ttgctagata taaggttaat tgggatagaa ttttgaataa agttgttgta
    21181 ttttgtaata gtgattgata ttgggataac cttaaaaaaa taatttgatt ttagattaaa
    21241 aggtttacaa gctttgattt taaagcattc taggactgtc ctagaatgct tttagttttg
    21301 ataagcacaa tccgctgttg actgtataaa ccgtatatga tacaaaataa gagcttgtag
    21361 cagtgaagcc actaactcta gtgctgtggg ctcaaccttg attgatgaat cccttgcttt
    21421 taatgcgttt atgaagcagt ggcgtatcag tctagctcgt tgtggaaagc aattaactag
    21481 agaagaatta ctatcctcaa tcaatatgct gacagccgca gggatttgtg agtttgattt
    21541 gctgtggcag cgtcttgctc ctaaggggtg tcagcgtccc aaatggagcc atcagctgga
    21601 gaggctcttt gcggatacaa agccttgtct acaggtcttg tctgagactt atcagcttgg
    21661 gattattgct aatcaggcaa agggtctaaa agagcgctta gagaggtttg ggattagtca
    21721 ttattttgcc cttatgatat cttcttctga tgtggggcta caaaagcctg atcttgctct
    21781 gtttcgctat gcacttgatc aagcaggcgt attagcgcgt gatgctgttt atattgggga
    21841 tcgtgttgac aatgatatta ttcctgctaa ggcattggga atgagagctg tcaggattca
    21901 tcaagggctt gctgcgtcca gtccagatga taggctttat cctagtgatg tccatattag
    21961 caaacttagt gacctgttag aatgctttta accagtcttt agcttgaact agcttttctt
    22021 tgtggtcttt ctgggtgaat ggcagcaagc tttggagtca tgttatggct agaccttgga
    22081 tctaagggcg ctgagcgtct catatgatga ggccgatcaa gtagtctcct tgacaagtag
    22141 attattgttt ggtgcttata ggtggcttta ggtgatgact ggttttgcct caactaaggc
    22201 tcgctattgc tatctggggt atcttctgac ttttttaatg tgctcttatc tggttggatt
    22261 agacctgctc cttgcttgag gaaagctgtt tttaacgctg atgagtctgg gaaatggtga
    22321 gattggtgtt ggcttttact agtttttttg cgtttacttg ggctaacttt atatgagaaa
    22381 aaaagaaaaa tatttatttt atctgttatt tttgttacaa taagcgtgta aactaagatg
    22441 cattaaaaag gagtttttat gtcgaataag aaatttttta cttatgcttc attattggca
    22501 ttaatcgctg ttcctactgt ggttgaagag gtgactgcac agccttcagc tcagcttgtt
    22561 tatgcagatg agctaaggct atcaccaagt accgactcat ctccagtaac aaagaccgat
    22621 gaggctgatc agccagttgc tcaatctgtt tctgcgacag aaccagtaga ggctcttgtt
    22681 attgcggata aagaaagcgc tttaaatcct gctgttctag ctgatgccga tggaagtcag
    22741 ccgattgcag tggttagagc tggtcaagag ggtcagcctt ataccgttac tggcaaaatc
    22801 atcagtgctg ttaatggctg gggtggtcat ggcttttata tccaggacag tcagggatca
    22861 ggtctttaca tttatccagg aagtgctttg gggtacgtga ctggtgatgt ggtgcagctg
    22921 acaggaacac tgactactta caagggtgag cttcagctta aaacgattac aaagcatcat
    22981 aagattaatg gcgaattacc aacacctatt gctgaggtaa ccattccgga gctagaaaaa
    23041 gcaagcccgt ctaccctggt gaagctttca aatgtgactg ttggagacat ttcatcagat
    23101 aagcacgaaa cctcctcttt taaggtcagc gatacagctg gcaatagtgt tgcggtgcgt
    23161 cttgataatc gtacaggtgt taagacctct gacttactct ctaaaattgg caagggtgat
    23221 gtgattaatc tgacagctat tcactcaacc tttgatggga agctccagct caagcccttt
    23281 agccttgagc aatttgaggt agtaaagaag gttgttcgag aagaagaggt gactcctctt
    23341 ggtcgagtgg ttaaaatcgg ccaaattcaa ggtgccagcc acacctcacc gctcttgaat
    23401 caagctgtaa cagtaaaaga ggtggtggtg acctatcttg atgatgcaac tcatttctat
    23461 gtgcaagata ttaatggtga caacgataag gcgacctcag acggtattcg tgtctttgct
    23521 caaaatgctc aggtgcaggc tggtgatgtg ctgaccattt ccggaacagt ggaggagttc
    23581 tttggcaaag gctacgatga ccgtaagcag acggatctga ccattacgca aatcaaggca
    23641 tctaaggtca ctaaaacagg gactgctcag gtaccagctc cgcttgtgct aggtaaggat
    23701 cgtgttgctc cagctaatat cattgataat gatggcttta gtgtttttga tccagaagag
    23761 gacgctattg atttttggga atccttggag ggaatgcttg ttgccgttga taatgccaag
    23821 attttagggc cgatgtctca taaggaaatt tatgtgttac cagggtcatc aactcgagtg
    23881 ctgactaact caggtggtat tttacttcct gagacaggct ataatacaga cctgattcct
    23941 gttctcttta aaaaaggaaa gcaaaccatc aaagctggtg attcctatca gggacgactt
    24001 gcaggtccgg tatcatatag ctatggtaat tataaggtgt ttgtcgatga cagcagtcgt
    24061 atgccagtct tggttgatgg tcagctgaag cctgaaaaga cacacatcaa gaaggacctt
    24121 agcaagctaa gcattgcctc atacaacatt gaaaacttct cagcaaaccc atcatcaaca
    24181 aaagacgaga aggtaaggcg cattgcagaa tccttcatct atgacctaaa tgctcctgat
    24241 attattggtc tcatcgaggt tcaggacaat aatggaccta ctgatgatgg cacaacagat
    24301 gcaacacaaa gcgctcagcg cttgattgat gccatcaagg ccttaggtgg accagcttat
    24361 caatatgtgg atattgctcc ggaaaataac gctgatggtg ggcagccggg cagtaatatt
    24421 cggacaggct tcctgtatca gccaggacgt gtcagccttt ctgataagcc tagaggtggt
    24481 gttaatgatg cggtgaaatg ggtaaatggt gagctaagct tgagtgttgg acgtattgac
    24541 ccaacaaatc ctgcttggaa tagtgttaga aaatcattgg ctgctgagtt tattttccaa
    24601 ggccacaagg ttgtggtggt tgccaatcat ttgaattcca aacgaggcga caattcatta
    24661 tatggacgtg ttcagccggt aacctttaaa tcagaggaaa gacgtcatgt cttagcaagg
    24721 cttttgagcc aatttactaa ggaaggtgct agtcagcagg ctaatatcgt tatgttgggt
    24781 gactttaacg attatgagtt tacgaagacc attaagctga ttgaagaagg agatatggca
    24841 aatttggtga gcaggcatga gctttctgac cgttattctt acttctatag aggaaataac
    24901 caaacgcttg ataacatgct tgtttcacgc aatttgcttg gtcgctacga gtttgacatg
    24961 gttcatgtga attcaccatt tatggaagcg catggacgtg cttctgatca tgatccgttg
    25021 cttcttcagc tctcctttgg aaaagacaag ccagcagcac catcagatca gccaaagaaa
    25081 acaccagcac cagctgcgac aactcaagcc tctaaggcag gacgtgcaca gctattgcca
    25141 aaaacaggtg ataagacagc gcttatggta agtattttag gcttaacagc tgtctttagc
    25201 tcctttagcc tgtttaggaa atgtcaggaa aggaagtaaa ggatttcttt ggggtaggcc
    25261 agcagctgag cggctactgc gttttgtctg ctggtgctat ataggtggtt gaagcgagcg
    25321 aagagaggta tgcttcctag gatcatagca caatatctta tgcttataaa cgaacacaat
    25381 gctccttatg agcattcaaa acctatactc aaaaggaata taacagctga gttaagaggg
    25441 attgcttttg acagattgtg gtaaaaaaag ggatcttgag gaattggcta gtgatctagc
    25501 tgccaaaatg cgatgtcttg tttgactatt tttccctatt gggatataat gacaatagaa
    25561 aaagggtagt tgtttgcgca actaccctgt gcagaaccgt ttaagacggt ggcagaatga
    25621 aagttaaaaa ataatcgtcg acctaccaaa gttcagacgg ttatttttta ttgtttaata
    25681 tgacgattgc aacgactaag ctgattaagg taagtaagaa actaccaaaa gccagcatga
    25741 gttgaagggc ctcgtaagta gacaataaaa cgctcctttc agttggattt tgatgcattg
    25801 cccataggca tcaccacctt tcagaaatca gagccaccgt cttagctttt ctgtaaagaa
    25861 cattatatca taatcacatg agaaagccgt tagattttaa actgatcagg cggctttttg
    25921 gtgttttgct gtcttttagt ggaatcgcct aagctttgct gtatagtatg ggattttatg
    25981 ctttttgtaa gggcttaggc tgctatggca gggtccatgt cctttgtcaa tagcttagtt
    26041 ttatggtaca atgtaggcgt tgcctagcaa cccttggtgc ttagttccct ttcaccaagc
    26101 atattacaaa cgtggcggag ctgtttatgc tctagtctga cgtcaaagga gaaacacatg
    26161 acaagtttta ctgttcgtga ctatgtttac attgctctag tggctgccct ttatgtggtt
    26221 ttgacaatca ctccaccttt gaatgctatt tcctatggca tgtatcaatt tcgggttgcc
    26281 gagatgatga attttttggc tttttaccat aaaaagtata tcattgcggt gaccttgggc
    26341 tgtatgattg ctaattttta tagctttggc ttgattgatg ttttggtggg tggaggctca
    26401 acgctcattt ttgttagctt aggtgtcgct ttatttaagc aataccaaga ggaatatctc
    26461 ttaaatggct tgctgaataa ggcctttgtt tatttctcac tattttttgc gacttctatg
    26521 atcaccgttg cgattgagct ttacttcttt ggagcaccat ttttcctaac ttggtttacc
    26581 actgctgtag gggaatttgc ttcacttatc attggctcta tgatcattga tcgcttatca
    26641 aaacgcatta atttacgaca ataatagtaa catgtagcct tccgtttttg ggaggctttt
    26701 tatgattttc ttctagctag gcaatagctt atttgctatg ttttgtgata aaataagact
    26761 atgaaaaaac gcataagaga attgactgat ctgttaaatc aataccgtca ggagtattac
    26821 accaatgacg ctccttctgt atctgatagt gagtatgata agctttatcg tgagcttgta
    26881 gagctggagc agacctatcc agcctatatc ctaaaggaca gccccacaca gctggtgggc
    26941 agtacgattt tgacaggatt tcagaaatat cagcaccagt atccgctctt tagtttgcag
    27001 gatgcttttt cacgtgaaga gcttaacgcc tttgatcagc ggatcaaatc agcctttcct
    27061 gaggctgaat accttgctga gctaaaaatt gatggcttgt ccatttcgct ggtttatgag
    27121 gctggtgttc taaaggttgg agcgacacgt ggcgatggga ctattggcga gaatatcact
    27181 gaaaacatta agaatattaa ggatattccc aaacggctaa gtcaagcact tgatgtgacg
    27241 atacgggggg aggcctatat gtcgcgtcag gcctttaaga cgatcaatga agagcgtcag
    27301 gaaaatggtg agccagaatt tgccaatcca agaaatgcag cggcaggaac cttgaggcag
    27361 ctggatacta ggattgttgc caagcgacag ctagcaacct ttttgtatca ggaggtaggc
    27421 ctagaaactg ctgatagcca gcaaaagacc ttggagcgct tggccgattt aggcttttcg
    27481 gtcaatagcc actatctgct gtcctcatcg atgaatgaca tttgggactt tatccagagc
    27541 attgaagcta gtagagaaga gctaccttat gagattgatg gtgtggtggt caaggttaat
    27601 cagttggcga tccaagagga acttggcttt accgtcaagg caccacgctg ggctattgct
    27661 tataagtttc cagcagaaga aaaggaagct gagattgtat ctgtggattg gacggttggc
    27721 cgaacaggtg tggtcacacc aacagctaat ttgacccctg tgcagctggc aggcaccact
    27781 gtcagtcgag cgaccttgca taatgttgat tatatcgcag aaaaggatat tcgcattggg
    27841 gatacggtgg tggtgtataa ggctggagat attattccag ctgttttgcg ggtggttgag
    27901 gctaagcgta gggatcaggc tccaatgccc attcctacag cctgtccttc ctgccagagt
    27961 cagctggtgc attttgagga cgaggtagct ttgcgttgca ttaacccctt gtgtccgagc
    28021 ttggttcaac ggagcttgga gcattttgcc agtcgtcagg cgatgaatat cgctggtctt
    28081 ggtccagcgg ttgttgaaaa gctttattct gctggcctgg tgcatgatgt ggcagatatt
    28141 taccgactaa gcttggagga tttgctgacg ctagatggta tcaaggaaaa gtcggctgaa
    28201 aagctcttgg cagctattga acaatcaaag gcaaactcag ctgaaaagct cttgtttgga
    28261 cttggtattc gtcatattgg cgcaaaggct agtcgtctga tattagaggc ttacggtgat
    28321 ttagaggcgc tgttagctgt aaccgctgaa gagctcgctc agattgacgg gcttggtcta
    28381 gtgatcggac aatccctggt gcagtatttt cagcaagagc aagccgctca gctgctagct
    28441 gaattaaaat cagctggggt taatctggct tatttaggcc aaaggcctga tcaacaggct
    28501 gcgctgtttg gtttaacggt ggtattgaca ggaaaattag aaaagctaaa ccgtacccaa
    28561 gccatggaaa agctagagca gcttggtgct aaggtaacag gaagcgtttc taaaaaaaca
    28621 gatttagtgg ttgctggcag cgaggcaggc tctaagctgg ctaaggccca gcagctgggt
    28681 atcagaattg aagatgagga ttggttgctc aatctttagt gaggtaataa catgaaaaaa
    28741 caaatgaggg ctcgtctgat ttacaatcca acctctggtc aagaaatcat gaaaaaaaac
    28801 gttgcagagg tgctggatat tttggaaggc tttggctatg aaacctctgc ctttcaaacg
    28861 acagcagcta agcactcagc cttaaaggaa gcaagaaggg cagctaaagc aggctttgac
    28921 ctcttgattg ctgctggtgg agatggtacg atcaacgaag tagtcaatgg cattgctccc
    28981 ctagagaaaa gacctaagat ggcgattatt ccagcaggaa ccaccaatga ttttgctagg
    29041 gccttaaagg taccaagagg caatcccgtt gaggccgcta agctgattgg taaaaatcaa
    29101 accatccgca tggatatagg acgtgctaaa aaggatactt attttatcaa catttcagcc
    29161 gcaggaagcc tgacagagct gacctatagt gtccctagtc agctcaaaac catgtttggc
    29221 tacctggctt atctggctaa gggagtggag ctcttgcctc gagtgagtaa tgttccggtg
    29281 aaaatcacgc atgatcatgg catttttgag ggagaggtat caatgatttt tgcagccatc
    29341 actaattctg ttggtggctt tgaaaagatt gccccagatg ctaagctaga tgatggcatg
    29401 tttaccctta ttttgattaa aacagccaac ctgtttgaaa ttgtgcacct gctgcggttg
    29461 atcattgacg gtggtaagca tgttacggat cgccgcgtcg aatacattaa aaccagtaaa
    29521 atcaccattg agccccaatc agataagcgc atgatgatta atttagatgg tgaatatggt
    29581 ggtgatgcgc caattaccct agaaaactta aaaaatcaca tcaccttttt tgcaaatact
    29641 gatttgattt cagatgatgc ccttgtccta gaccaagagg agctggaaat cgaagaaatg
    29701 gtcaagaaat ttgcgcatga ggtagaggat ttagagcagg gattggagga atagggctag
    29761 ttatggataa tgcagttatt gttcattatc atagttgcaa gggacattat tttcaattaa
    29821 gtctatggca atggcgagat ggtaagctgg gcaaggacgc ttatttttcg aggtttgaca
    29881 gctttggagc agttgcttat ctcacttatc cagcacctta ttttttgagt catgcttatg
    29941 tgattgtaaa ggatcagttt tggcagcatc aaaccgttga ttttcggatt gagcgtgatt
    30001 atggggttcc aaagactgag gtgtggcttg ttgatggtga tcctacggtt tattattcga
    30061 gacaggctgc tgtggctagt cgacatgatg gtagatgtga tgtgcatgcc tttgatatgg
    30121 ctgtcaatag tcaggccttt gacaagcgct ggggctttag tggctggcta ggctttcgct
    30181 atcagcctga ggagacgtct tttcgtttgt gggctccaac agcagaaaag gttgagctca
    30241 ttctctatgc ttcgactgat gagagagcta gtgttgccaa ggttttgccc atgcagcgtg
    30301 ggcagcagta ctcgccagat catcatgcag aaaacacatg tggtgtgtgg gacatcagcc
    30361 taagaggtga ttataattac catgcttatt gctaccgggt ttattatcgc aggcgtacct
    30421 ttagagacac tagggatcct tatgcgatcg caacgacagc aaatggcaaa aggtcaattg
    30481 tcattgcacc ggagcattta agaccgcagg gcttttcagt gaagcagggt aaggaggcta
    30541 cctggcgctt agacaatcct aatcaggcgg tgatctatga aatgcatgtt cgcgactttt
    30601 caaaatcaga aacctcgggc gttagcttgg ctaatcgtgg caaatttaag gggctgattg
    30661 agacaggcac gcgcaatgct tttggagatt caacctgctt tgattatgtc aagtcccttg
    30721 gcattacgca tattcagctc cagccggtct ttgaccatca tcaattcttt gatgaaaatg
    30781 gagattatgc ctataattgg ggctatgacc ctgaaaatta caatgttcca gcagccagct
    30841 ttaccagtaa tccgcatgag ccagctaccc gtatcctgga attaaaggag gtcattcagg
    30901 cttatcatga tgcaggcatc aatgtgatca tggacgtggt gtacaatcat acctactcat
    30961 caagagagtc agcctttcag ctgacggttc cggattatta ttaccgtatg aatcctaatg
    31021 gctcctttca aaatggctct ggctgtggca atgaaacggc tagtgaaaag gaaatgtatc
    31081 gcaaatacat gcttgattcg atcctatatt ggaccaatga gtttaacatt gatggcttca
    31141 ggtttgatct gatgggctta cacgatattg acaccatgaa tcttatccga caagagctag
    31201 ataagattga cccaaggata cttgtttttg gtgagggctg ggatatggga gttggtctgg
    31261 cagctgagca gaaggctaaa aaaggaaatg ccagccaaat gcctggaatc ggctttatta
    31321 atgatgatca gcgtaatgca gttaaggggg cagaggtcta tgggagctta gagaagggct
    31381 ttgtatcagg tgcaccgaca gaaggacttg tagccaagtc tattttgggc agtgatgagc
    31441 tggtctctta ttgtacgcct agtcaggtga tcaattatgt tgaagctcat gacaactata
    31501 acctcaatga tttgctgtgg gttttgaatc cagaggacag caagcaggat catgtcaaac
    31561 gggttcagct agcttcagct atgacgattc tcatgcaagg gatttacttt atgcagctgg
    31621 gtcaggaatt tttacgaaca aagctttacc caacaggtca ggataaggag ctgacacagg
    31681 cagaccgaga aagggcgatg aattcctaca atgcacctga caatgtgaat caggttgact
    31741 ggagacaggt tagcttggag cgcgaaacgg ttgctattat gaaaaaacta atctatctga
    31801 aaactaaaac agctttgttt tcatacccat catttgagca aatcagacag catgtttaca
    31861 ttgagcatgc tggtgaaaat acgggcttca ttagctttac agtagaagat gaaagaaagt
    31921 atcgattgat tttctctagt tttagaaacc gcttgcaatc atctgctaat catgttataa
    31981 ttgaaacaaa tgataagcgc tttcaagata gtgagtccat gctagatgag ctgacagcga
    32041 tgatccttga catcacacaa tagcctgagt gttctcaggt tatttttgtt tgttgtcaag
    32101 gataaaaggg ctgtagttac agttagcaga gacctattag gaccttgctt atcatatcgc
    32161 ttagcgcctt gaaaaagggt ttaggagtag ggaaagaaga ggtgatggga tggataatga
    32221 cttagcgctt tatacctttg gcacaggtga gaattttcac atacaggatt atctaggtgt
    32281 tcatcggatt aacaatgaca caggcaccag ctatgtcttt agggtatggg cgcccaatgc
    32341 agaggctgtc agcttgattg gagattttac tgattggcag tccaatccac ttgagatgag
    32401 ccgaaatgag gctggcgtgt gggaggttac cactagcttg ccgcaggaag gagatattta
    32461 taagtattgg gttaggcgcc aaggtggtca gcttgttgaa aaaattgatc cagtggcctt
    32521 tctatttgaa gctagaccag gaacgggtgc tattgtcaaa acccttccag ccaaaaaatg
    32581 gcgtgatagc ttatggatgg gacggcgaaa gcgttttggc tttaggcagc gtccggttaa
    32641 tatctatgag gttcatgccc attcatggaa aaaagacgaa aacgcaaggc cctatgactt
    32701 tagcaagcta aaagaagagc tcattcccta tctcaagagc atgcactaca ctcatgttga
    32761 gtttatgccg gtcatggctc accccttaga tatgagctgg ggctatcagc tgatgggcta
    32821 ctttgccttt gagtcaacct ttggaagccc agaagccttt caggattttg ttgaggcctg
    32881 tcatcttaat aatattggtg ttttgattga ttgggtgccg ggacatttta cacaaaatga
    32941 tgacgcctta gcttattttg acggtacagc tacctatgaa tatcaggatc accatcgtgc
    33001 tcataattat ggctgggggc cctaaatttt gatttgggta aaactcaggt acagtccttt
    33061 ttgatttcaa gtgccctttt ttggctggag gcttatcatg ttgacggcat tcgagtagat
    33121 gctgttagca atatgcttta cttggattat gatcaaggcc cttggactcc gaatcaatac
    33181 ggtggcaacc aaaaccttga ggggatagcc tttcttcaaa aattaaccac agttatcaag
    33241 gaaaaacacc ctgatgtgat gatgattgca gaggaggcga cctcagctac cccaataacc
    33301 agccctgttg cagaaggggg actaggcttt gattataagt ggaatatggg ctggatgaat
    33361 gatattctta ggttttacga agaggatcct tattaccgaa aatacgattt caatctcttg
    33421 acctttagct ttatgtattg ctttaaggag cattacattt tacccttttc tcacgatgag
    33481 gttgttcatg gcaaaaaaag cctcatgcat aaaatgtggg gggaccgcta caatcaattt
    33541 gcaggcctaa gaaatcttta cacctatcaa atctgccacc caggcaagaa gctgcttttt
    33601 atgggatctg agtttggaca gtttttggaa tggaaatacg atcatcaatt agagtggcaa
    33661 aatttagagg acgagctcaa tgccaaaatg cagcatttca cagccagcct aaatcagcta
    33721 tataaggacc atagcatgct gtggcaaaat gatgaaacct atgacggcat tgatattatt
    33781 gatgcagaca ataaggacga atcagtcttg tcgttttgtc gtcaaaacaa taaaggagag
    33841 ctcctgcttt gtgtctttaa catgacacct gttgaaagac caggctttac cataggtgtg
    33901 ccgatagcag gtctttatca agaaattttc aatacagagc ttgaggcctt tggaggtgtc
    33961 tggaaggagc acaatccctt aaccaacaca gtagccaaga aatggaagac ttatccgcag
    34021 accttgagct ttaccctgcc tgcactagga gcaagcatct ggaaaatcaa gcgtcgtcag
    34081 aagcaataag ctattcattg cttacttagc tgtttcaacc aaaagaagtc actacagtca
    34141 tgaaaggata acgaaatgaa gaatggaatg ttagccctca tattagcagg gggacaagga
    34201 actcgcttag gaaaattgac acagagcatt gcaaagcctg ctgtgcaatt tggaggtcgg
    34261 tatcgtatca ttgattttgc cctatccaat tgtgctaact cagggattca taatgtgggg
    34321 gttatcaccc agtaccagcc tcttgcctta aataatcata ttggcaatgg ttcgtcatgg
    34381 ggcttagatg gtattaattc tggcgctacg attttacagc cctactctgc aacagaggga
    34441 aatcgctggt ttcaaggaac tagccatgct atctatcaaa atattgatta tattgatagc
    34501 attaaccctg aatatgtgct gatcctgtct ggtgatcata tttacaaaat ggactatgat
    34561 gacatgcttc agacgcataa ggctaatatg gctagcttga ctgttgctgt gattgatgtt
    34621 cctctaaagg aagccagtcg atttggcatt atgaacacag ataccaatga ccgcattgtc
    34681 gaatttgaag aaaagcctgc caatccaaaa tcaaccaagg cttcaatggg tatttatatc
    34741 tttaattggc agcgccttcg gaccatgctg gttgacgcag aaaaaaacaa cattgatatg
    34801 tctgactttg gtcagcatgt gattccgtct taccttgagt ctggcgagcg tgtctacacc
    34861 tataacttta aaggctactg gaaggacgtc ggaacgattg agtctctctg ggaagccaat
    34921 atggaataca tcggtgagga aaatgcccta gacagtcgtg atcgttcttg gaagatttat
    34981 tctaaaaacc atatcgctcc accaaacttt atcacagagg acgccgaggt caaggattct
    35041 ctggtagtag atggcagctt tatctctggt aaggtcaacc attctatctt gtctaccaat
    35101 gtgcaggtaa gaaagggagc cgaggttaag gattccttta tcatgagcga tgttatcatt
    35161 ggtgagggtg caaggattac acgagctatt attggtgagg gtgcagtcat tggtgatcat
    35221 gtgatcattg atggcagcaa ggacgttcaa gtcgtaggct ataatgaagt agtgggggta
    35281 ccaaatgaag attgataaat attctgccat tctaggcagc tcaattggct ttgctgaaat
    35341 gaaggggcta acagacacaa gaccattagc caacctaccc tttgatggga aataccggct
    35401 cattgatttt caattgtcca accttgccaa tgcaggtgtc cgtagcatct atggtatttt
    35461 tcgtgggcaa aatatccgct cagtgtttga tcatatcagg tcaggtcgtg aatgggggct
    35521 taattcctta ctaagtcatt atttccttgg cttttataac accaaggagg attctaaaga
    35581 ggctgacaag gactattatc agcagatttt gacctattta aagcgctcag ggtcagatca
    35641 gaccatttac atgagctgtg atattctctg caatattgag cttgggcagg ttattcatct
    35701 gcacaatgcc aaccatcgca acattacggt tgtctacaag aaaatgccga ccaaggccat
    35761 ctctaaggct aacgatattt tagatattga cgagacagat actgttgttg acaggcgaag
    35821 tctgtctgag gggcaggagg ttgaaaaaat gtcagcaggc atttacatcg tcaatacccc
    35881 atggttaatt gaacagatgg aaaaagaagc cgaaaaagaa aaccctcaaa agctacgctt
    35941 cctcttacgt gatttgattg tgtcagaggg cgctcttggc tttgaatata ctggctatct
    36001 tgccaatatt cactctgtta aatcttattt tgatgccaat atggacatgc tggatccgca
    36061 taagttttat tcactattat atgctaatca gaaggtctac acgcgtgtca aaaatgaaga
    36121 gtcaacctat tttgatgcgg cttctgaggt gaacaatgcc caatttgctt caggaagcat
    36181 tgtcaagggc tatgtcgagc actcaattgt ctctcgcaat tgtcgcatta cctcacaggc
    36241 acgtgttaca aatagtattt tattgccaaa ggcagtgatt ggtgagggtg ctgtcattga
    36301 ttatgctatc attgataaat ccgtaagggt tgcaccaggt gttactatta gaggaagcgc
    36361 tgaggagcca atagttgttg ccaaggggac tgaggttgtt gaggatatga taaaatgaag
    36421 ataatgtttg ttgcagcaga gggagctccc tttgctaaga caggtggcct aggcgatgtc
    36481 attggggcat tgcctaaatc acttgttaaa aatggtcatg aggtgtctgt gatactgcct
    36541 tattatgacg tggttgatca agcctttggt cagcaggttg aggacgtctt gtatttttat
    36601 acgcaggttg gctggagacg ccaatacgtg ggcattaaaa agcttgtcaa ggataaggtg
    36661 accttttact ttattgacaa tcaaggttat ttctttagag gcaggatcta tggtgattgg
    36721 gacgacggtg agcgctttgc ctatttccag ctggctgcca tagaagcaat ggagaaaatc
    36781 ggggttattc cagatatttt gcatgtgcat gattaccata ccgctatgat tcctttccta
    36841 ttgaaagaaa aataccattg gattcaggcc tatcaagcga ttcggacagt ttttaccatt
    36901 cataatatcg catttcaagg gcagtttgat cctggcatgc taggcgattt gtttgatgtt
    36961 ggtatagagc gctacgagga tggcaccctg cgttggcatg attgcttgaa ttggatgaaa
    37021 gcagcagtcc tatatgcaga tcgggtaacc actgtctcac cctcttatgc gcatgaaatt
    37081 cagacaccag cctttggaca aggcttggat caagtcatgc gaatggaggc aggcaagcta
    37141 tcaggcattg tgaatggtat tgacactgac ttatttaacc cagcaaggga tcctcatttg
    37201 cctgcttcat tttcagcaga agacctatca ggcaaggcgg ctactaaaca ggccttgcag
    37261 gagcggttag gattaccagt cagggcagat gttccattga ttggtatggt ttcgcgcttg
    37321 acggatcaaa agggctttca gcttgttctt gaggaattac cgcatatctt gcagcaggac
    37381 gttcagcttg tcttgttagg aacaggtgac cctgattatg aggctgcctt ttcatggttt
    37441 gccaaggcct atccagaaaa actgtctgct aatattacct ttgatctgcc attagctcag
    37501 cagatttatg gggcctgtga tctcttttta atgccaagtg cttttgagcc ctgcggactt
    37561 tcgcaaatga tggctatgag atatggcgcg ataccgattg tccatgagat cggcggcttg
    37621 aaggatactg ttgcctccta caatgcttat gaaaagactg gaactggttt tggctttgat
    37681 cagttttcag gattttggtt aacgcagacg ctcttgtttg cccttgatat ttaccataac
    37741 cacaaggagg attggcagac tattcaacaa catgccatga ccaaggattt ttcatgggat
    37801 acagccagtc tggcctacct tgatttatat aaaagcttac tataacacag aaaaggaatg
    37861 ggaatgcacg tcacaaaaga acaatttatt cgagatttta aagatacctt acatgaggaa
    37921 caattgatca aggttcctgc cgcaacagct gctgagcttt tcacctcatt agcaaagctt
    37981 atccgtaaat actatacaga tacttggatt gaaaggaatc gttccttaac cgaacagcag
    38041 caaaaaattg cctattattt ttcgatcgaa tttttaccag gaagaatgct agaaacaaat
    38101 cttcttaatt taggcattct tgatacagtt aaagaagcct ttgctgactt gggaattgat
    38161 tttcaagcag tgaagcatgc agagcacgac atggctctag gcaatggagg tctaggacgt
    38221 ttggcagctg cctttatgga ttcgctagcg acaacaggct atccaggctt tggaaatggg
    38281 ctgcgttatc gttatgggct gtttaagcaa cggattgtga atggttatca ggtagaatta
    38341 ccagattctt ggtttggctc tattggtaat gtctgggaga tcagaaagga tcatgacatt
    38401 gtagacgtca agctctttgg gaatgtttac ctaaaagcca atcaggacgg taagctagcg
    38461 ccaatctatg agggagctca ggttttgaga gctgttccct acgatgttcc tcagattggc
    38521 tttgaaaatg atgtgattaa caatcttcgc ctctgggacg tagaaatccc agaagaacat
    38581 gagcttgatt acccaaccat cgagtcaaga cgggcagtca aggacattac tgccattttg
    38641 tacccagacg acagcagcta tgaaggcaaa aagcttagat tgatccaaga atatttcatg
    38701 accagcgcag gcatccaaac cattatcaaa tcctatttaa agcagggctt gccacttact
    38761 gagcttcatc aaaaggtatc tgttcatatc aatgataccc acccagcagt agctccagca
    38821 gagcttatgc ggctcttgat tgacgactat ggcttagaat gggtagacgc ctgggcgaca
    38881 accgtaaaaa ccatgagcta taccaatcat acgattttgt cagaagcctt agaaaaatgg
    38941 gacgcagagc tctttaagac tgtgctgccc cgcgtttatc aaatcatttt agagattgat
    39001 catcgctttg ttgctgaaat ggcgcaaaag ggtattgatc ctcagatcat tgaaaacact
    39061 agaatcgtta aggacaacca gatttatatg gctaatcttg ccattattgg tggctattcg
    39121 gtcaatggcg ttgccaagct acatacagag ttgttaaaga cagataccct taaggacttt
    39181 tatgccttgt atcctgaaaa attcaacaac aaaaccaatg gtatcgtgca aagacgttgg
    39241 acacagattg ctgcgccaga gctatcagca gctattgacc gcacgattgg caaaggctgg
    39301 cgcaaggata ttcaccagct tcgacaattg agtcaattta cagaagatcc agctgtgcta
    39361 aatgattttt atcaggtaaa acaagcagct aagcagcgcc tagccaggta tatcctggaa
    39421 aaaacaggtc ttgaggtttc aacagaggct atttttgatg tgcaggtcaa acgcctacat
    39481 gcctacaagc ggcagctcct gaacgtcctg catattatga agctttacct tgatttgaag
    39541 gctaatccag atttagatat ggtgcctaga gtctttattt tcggcgcaaa ggctgcacca
    39601 ggctatcatt ttgccaagtc ggtgatcaaa atcatcaatg agctggctaa tctcattaac
    39661 catgatacca gtctcaaagg aaagctaaag gttgtttttc ttgaaaatta taacgtgagt
    39721 ctagcagagc tcattatccc tgcggcagat atttcagagc agatttcact ggcctccaag
    39781 gaagcctcag gaacatcaaa catgaaattt atgatgactg gtgctatcac cctagcgacc
    39841 cttgatgggg caaacattga aatcaaagac gaggtcggag aggaaaacat tgtgatcttt
    39901 ggtatggata aggatcaggt ctatgaccac tatgccaagc atgattatta ttcaagaggc
    39961 ctatatgaga gcgaccctca gattaaagca gtagtcgacg cttttgtcaa tggcaccatt
    40021 ccaaatagtc aacacgaagg tatggaaatc tatgatgccc taatcacgca taatgatgaa
    40081 tacttcttgc tagaagactt ttcttcctat gtaaaagcac aggctaagat tgatcggctc
    40141 taccgccaaa aggatagatg gtcaaaaatg tcgctcatca acattgccca ttctgacaag
    40201 tttacatcag atgataccat cacccagtat gccaaggaca tttggcagct aaaacgctaa
    40261 tccatcaagg aagaaaaagc attagttacc ttagattgaa gagagtgtct tttgagacca
    40321 ttttcttcaa tcttttttga ttgcaaaaga ccttgggaat cagatcagct gcctgcctaa
    40381 tactttggcc tatcaaggta ttttggaatt tgttaatctt tttgttataa tagtggtgtg
    40441 aagctatttt ttaaatgaaa aagccaacac ttcaagatgg tgttaaagta aggttagtat
    40501 tagtctaaga aagcgtaacc acattaaaga aagctgttga cattctcaat tttaaggaat
    40561 agaataacaa agtaaaaaat ttttaaaagg agtattctat tatgaatcct attttcgcat
    40621 tggctcttgc ctgctttggt gtatcacttg ccgaaggctt tttgatggct aatctcttta
    40681 aatcagcgtc acgccaacca gaaattatcg gtcaattacg ttccttgatg atcctaggtg
    40741 ttgcctttat tgaaggtacc ttcttcgtta cccttgttat ggccttcatt ctaaaataac
    40801 agcctatttg atatagaaaa ggagggtatt aaatggaaga agctaaagta ccgatggtag
    40861 agcttggtcc aataaccttt aatttgaccc tacttgctgt ttgtattgtt actatcctac
    40921 tgatatttgg ctttgttttt tgggcaagtc gtcagatgac attaaaacca aaaggcaagc
    40981 aaactgcgtt agaatattta atcagctttg ttaatggtat tggggaagag catttggata
    41041 gtcatcttca gaagtcttat tcgcttttac tttttaccat ttttcttttt gtggcagttg
    41101 ccaacaactt gggcttattt acaaagctag aaacaaccag tggctacaac ctatggacat
    41161 cgccaacagc taatttggcc tttgacctag ccctatctct gtttgtgacg cttcttgttc
    41221 atatcgaagg cattagacgt cgtggttttg gcgcttattt aaaacgcttt gcgacacctt
    41281 ggccaatgac tccgatgaac ctattagaag aatttaccaa cttcctatca cttgctatca
    41341 ggctgtttgg taatatcttt gcaggagagg ttgtgacagg cttgattgtt cagctggcca
    41401 attatcgcct gtattggtgg ccaattgctt tccttgttaa tatagcatgg acagcctttt
    41461 ccatatttat ttcctgcata caagcctttg tatttacaaa attaacagca acgtatttag
    41521 gaaaaaaagt taatgaatca gaagaataag aagggaggac aaacgaatgt cagttacaat
    41581 tggtgagctc attgggaatt ttattctggt aacaggctct gtcatcgtct tgttgctctt
    41641 gattaaagcc tttgcttggg gtgctatcga agctgtttta caggcacgct cacagcaaat
    41701 ttcacaggat attgaccaag cagagcaggc gcgtctcaac gcccagcagc ttgaaaagga
    41761 aggtcaagcc aatctagaag ccagcagatc agaggctagt cagattgttg aggcagccaa
    41821 agaaactggt aaagcacagg agacacgcat tgtagcagag gctacagaag aggcagatcg
    41881 cctaaaagca gcagcgttga cagatatcga acacagcaag tcagaggcta tttcagccgt
    41941 taagacagaa atgtcagatt tgacagtttt actagcagaa aaaattatgg gagccaatct
    42001 tgataaggcg gctcaaagcc agcttattga tcgctatctt gatgatttag gagaggctta
    42061 atgaccaaaa aagaacaagc tcttatcgag caatatgcaa aaagtcttgt gcaggtctgt
    42121 caggagcgag acactcttga agcactgcag gctgatgtgc ttgccatttt agaggttttt
    42181 aaagctacta atcttgctaa gacattgtca agcttagcgg ttccacgtgc taaaaggctt
    42241 gagctagtaa ggcagcttca aggagataat atcgtttatc tgaataactt gctagaagtt
    42301 atgctgcaaa atgagcgtga agcttattta tatcaagtgc ttctaagggt tttatccgag
    42361 ctggctagtg tctcaaatca atatgacgtg acagttacat cagcagttcc tttaagtgag
    42421 gagcaaaagc agcgtgtgcg tacagtggtt tcaaagagac ttgcagtaaa gacaggtcgc
    42481 ttaatcgaaa aggtagatcc ttctttaatt ggaggattta tgattagcgt caataataag
    42541 gtaattgata caagcattcg tcgtcaatta caagcattta aaatgaattt aaaatagaaa
    42601 gtggtgtgac ttttggcaat taatgcacaa gaaattagcg ctttaattaa aaagcaaatt
    42661 gagaacttcc agccaaattt cgatgtcaca gaaactggag ttgttaccta tattggtgat
    42721 gggattgcac gtgctcgtgg cttagacaat gcgatgagtg gcgagcttct tgaattttca
    42781 aatggtacct tcggtatggc tcaaaaccta gagtcaaacg atgttggtat cattattctt
    42841 ggtgattttt caacgattcg tgagggtgat gaagtcaaac gtaccggtaa aattatggaa
    42901 gtgccagtcg gtgaagctct cattggacgt gtggtcaatc cacttggtca gcctgttgat
    42961 ggcttaggtg acattgagac aactggcttt aggcctgttg aaactccagc tcctggtgtt
    43021 atgcagcgta agtctgtttt tgagtcctta caaaccggtc taaaggctat tgatgctttg
    43081 gttccgatcg gtcgtggcca gcgcgagctg attatcggtg accgtcagac aggtaagacg
    43141 tctgtagcca ttgatgccat cttgaatcaa aaggggcagg acatgatttg tatctatgtc
    43201 gctattggtc aaaaggaatc aacagttcgg acacaggttg aaaccctacg tcgttatggt
    43261 gctttggatt ataccattgt tgtaacggct tctgcttcac agccatcacc cttgctgttt
    43321 attgcacctt atgctggtgt tgcgatggca gaagagttta tgtacaatgg caagcacgtt
    43381 ttgattgttt atgatgacct gtctaagcag gcggtagctt atcgtgaatt gtcgctcttg
    43441 cttcgtcgcc caccaggtcg tgaggcctat ccaggagatg ttttctacct gcatagccgc
    43501 ttgcttgagc gctcagctaa ggtgtctgat gacttaggtg gtggctcaat tacagcctta
    43561 ccatttattg agacgcaggc tggggatatc tctgcctaca ttgcgacaaa cgtgatttcg
    43621 attacagatg gtcagatttt cttgcaagag gatctcttta actcaggaat ccgcccagct
    43681 attgatgctg gctcgtcagt atctcgtgtc ggtggctctg cacagatcaa ggctatgaaa
    43741 agggttgcag ggactttgcg tcttgaccta gcctcttatc gtgagttaga agcctttaca
    43801 caatttggct cagatctaga tgcagcaacg caagcaaaat taaatcgtgg tcgtcgtact
    43861 gttgaaatcc taaagcagcc actgcacaag cccttgcctg ttgaaaagca ggtggtcatt
    43921 ttgtacgctt tgacgcatgg atttttagat gatgttcctg tagatgatat tttagccttt
    43981 gaagaagcac tttatgacta ctttgatgcg cattatgatc acttatttga aacaatccgt
    44041 acaaccaaag accttccgca ggaggctgag ctggacgttg ctattcaggc cttcaaagca
    44101 cagtcaaact ttaaataaaa gaggggggta ctagtatggc aggctctcta agtgaaatta
    44161 aggctaaaat catttcaacc gaaaaaacaa gcaaaatcac tagcgccatg cgtatggttt
    44221 cttctgcaaa gcttgttaaa tctgagcaag cagctcgtga ttttcaaatc tatgcttcaa
    44281 agattcgtca gattacaaca gacttactga aatcagacct gacaacaggc tcagataatc
    44341 ccatgctggt gtctcgtcct gtgaaaaaga caggctatat tgttattacc tctgataaag
    44401 gactggtcgg tggttacaat tcaaaaatct taaagtccat tatggacatg attcaggaat
    44461 accatgccgc tggcgattat gagattatct caattggcag catcggctca gattttttta
    44521 aggccagagg tatgaatgtt gcctttgagc tgcgcggcct agcagatcag ccaagctttg
    44581 atcaggtcgg aaggattatc tctcagtctg taggtatgtt tgtcaatgag atttttgatg
    44641 agctgtacgt ctgctacaat caccatgtca atagcttgac gagccaggtt cgggttcagc
    44701 gcatgctgcc gatttctgat ttggttgccg aggaggccgc agaagaaggt gtcactggat
    44761 ttgaattaga gccaaaccgt catgtgattt tggagcagct gctgccgcaa tttactgaaa
    44821 gcttaattta tggtgcgatt attgatgcaa aaacagcaga gcatgctgct ggcatgactg
    44881 caatgcagac tgccactgac aatgccaagc atgtgatcaa tgatttgacc atccagtaca
    44941 atcgtgcgcg tcaggcggcc attacacaag aaattacaga aattgtagct ggtgctaatg
    45001 cacttgaata agcttattgt atgctgatag cgctctagca gagacctatt agcacttaat
    45061 gtcatcttca aagctagatg acatttggga ttaatgagct aggggccttt tacccttagc
    45121 tactcgaatt tagaaaaatt cagcttaatc ccctactatc gaatataagg agaaaaacat
    45181 gagctcaggc aaaattgctc aggttgttgg tccagttgta gacgttgtgt ttgcgagtgg
    45241 ggacaaacta ccagagatta ataatgcgtt gatagtttat aaagatggcg ataaaaagca
    45301 aaaaatcgtt ctcgaggttg ccctagagct tggagacggt atggtacgta caattgctat
    45361 ggaatcaacc gatgggctta cacgtggatt agaggttctt gatactggtc gtgccattag
    45421 tgtaccagtt ggtaaagaga ctctaggtcg tgttttcaac gttcttggtg aaaccatcga
    45481 cctagaagca ccatttgcag atgatgttaa tcgtgaaccg atccataaaa aagcaccagc
    45541 ctttgatgaa ttgtcaacat catcagaaat tcttgaaaca ggtatcaagg ttattgacct
    45601 gcttgcccct tacttaaagg gtggtaaggt cggtcttttc ggtggtgccg gagttggtaa
    45661 aaccgttctt atccaagaat taatccacaa tatcgctcaa gagcatggtg ggatctcggt
    45721 atttaccggt gttggtgagc gtacgcgtga aggaaatgac ctttactggg aaatgaagga
    45781 atcaggcgtt attgaaaaaa cagccatggt ttttggtcag atgaatgaac caccaggagc
    45841 ccgtatgcgt gttgccttga ccggcttgac aattgctgaa tatttccgcg atgttgaagg
    45901 ccaagacgtc ctgctcttca ttgacaatat tttccgcttt actcaagcag gctcagaggt
    45961 atcagccctt ctaggtcgta tgccttcagc cgttggttac cagccaacac ttgccactga
    46021 aatgggacaa ttgcaagagc gtatcacctc aacgaaaaaa ggctctgtta cctctatcca
    46081 agccatctac gtgccagctg atgactacac tgatccggcg ccggcaacag catttgctca
    46141 cttggattct acaactaacc ttgagcgtaa gctgacgcag atggggattt acccagcggt
    46201 tgatccactg gcttcaagtt cacgcgcgct gtcaccagaa attgttggtg aggagcacta
    46261 tgcagtagcc acagaggttc agcgtgtctt gcagcgctat cgtgaattgc aggatatcat
    46321 tgctatctta ggtatggacg agctgtcaga agaggaaaag acattggtag gacgtgcgcg
    46381 tcggattcag ttcttcttat cgcaaaactt taacgtcgca gaacagttta caggccttcc
    46441 tggctcttat gttccagttg ccgaaaccgt tcgtggcttc aaggaaatcc tagaaggaaa
    46501 gcatgaccac cttccagaag acgcctttcg tgctgttgga ccaattgagg acgtgatcga
    46561 aaaagctaag aaaatgggct tttagtgagg tgatgccatg acacaaatga ctgttcaggt
    46621 ggttacgcca gatgggatca aatatgatca tcatgctaag ttcatctcag taacgacacc
    46681 agatggtgag atggggatct tacctaacca catcaatgtg attgctcctt tacaggtgca
    46741 tgaaatgaag attcgtcgtg tcagtgaaga cgatcgcgtt gattgggttg ctatcaatgg
    46801 tgggatcatt gagatcaaag acaacgtggt taccattgtt gcagattcag ccgaacgtga
    46861 tcgtgatatt gatgttagcc gagcagagcg ggcaaaattg cgagcagagc gtgacattgc
    46921 agaggctgaa accactcatg atattgatga ggtgcggcgt gctaaggttg ctttgcgacg
    46981 tgccttgaac cgcatcaatg ttagtaaaaa atagtaaaat gagtctaacc taccaattta
    47041 accaagacag agcgagtagc gctgcttagg aaagggtgta gatagactct tttatctttt
    47101 tatagaaaaa ataccctctt t
//
LOCUS       DARYXZ010000013        45359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYXZ010000013 DARYXZ010000000
VERSION     DARYXZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            398..811
                     /locus_tag="TV186_000627"
     CDS             398..811
                     /locus_tag="TV186_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1532046.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1071..1652
                     /locus_tag="TV186_000628"
     CDS             1071..1652
                     /locus_tag="TV186_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL1532047.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2062..2388
                     /locus_tag="TV186_000629"
                     /pseudo
     CDS             2062..2388
                     /locus_tag="TV186_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2457..4460
                     /locus_tag="TV186_000630"
     CDS             2457..4460
                     /locus_tag="TV186_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1532048.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4457..5065
                     /locus_tag="TV186_000631"
     CDS             4457..5065
                     /locus_tag="TV186_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1532049.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5254..7980)
                     /locus_tag="TV186_000632"
     CDS             complement(5254..7980)
                     /locus_tag="TV186_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL1532050.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7995..9281)
                     /locus_tag="TV186_000633"
     CDS             complement(7995..9281)
                     /locus_tag="TV186_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL1532051.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            9414..10472
                     /locus_tag="TV186_000634"
     CDS             9414..10472
                     /locus_tag="TV186_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1532052.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            10487..12181
                     /locus_tag="TV186_000635"
     CDS             10487..12181
                     /locus_tag="TV186_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL1532053.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            12208..13599
                     /locus_tag="TV186_000636"
     CDS             12208..13599
                     /locus_tag="TV186_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1532054.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            13586..13723
                     /locus_tag="TV186_000637"
     CDS             13586..13723
                     /locus_tag="TV186_000637"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532055.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(13919..16093)
                     /locus_tag="TV186_000638"
     CDS             complement(13919..16093)
                     /locus_tag="TV186_000638"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL1532056.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(16081..16974)
                     /locus_tag="TV186_000639"
     CDS             complement(16081..16974)
                     /locus_tag="TV186_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1532057.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            17186..18136
                     /locus_tag="TV186_000640"
     CDS             17186..18136
                     /locus_tag="TV186_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1532058.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            18146..19072
                     /locus_tag="TV186_000641"
     CDS             18146..19072
                     /locus_tag="TV186_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1532059.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            19156..20601
                     /locus_tag="TV186_000642"
     CDS             19156..20601
                     /locus_tag="TV186_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1532060.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            20949..21554
                     /locus_tag="TV186_000643"
     CDS             20949..21554
                     /locus_tag="TV186_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL1532061.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            21544..23268
                     /locus_tag="TV186_000644"
     CDS             21544..23268
                     /locus_tag="TV186_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1532062.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            23268..24752
                     /locus_tag="TV186_000645"
     CDS             23268..24752
                     /locus_tag="TV186_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1532063.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            24766..28209
                     /locus_tag="TV186_000646"
     CDS             24766..28209
                     /locus_tag="TV186_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL1532064.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            28360..29244
                     /locus_tag="TV186_000647"
     CDS             28360..29244
                     /locus_tag="TV186_000647"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL1532065.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            29370..30143
                     /locus_tag="TV186_000648"
     CDS             29370..30143
                     /locus_tag="TV186_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL1532066.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(30475..31557)
                     /locus_tag="TV186_000649"
     CDS             complement(30475..31557)
                     /locus_tag="TV186_000649"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL1532067.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(31616..32371)
                     /locus_tag="TV186_000650"
     CDS             complement(31616..32371)
                     /locus_tag="TV186_000650"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL1532068.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            32809..32979
                     /locus_tag="TV186_000651"
     CDS             32809..32979
                     /locus_tag="TV186_000651"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532069.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            33886..33956
                     /locus_tag="TV186_000652"
     tRNA            33886..33956
                     /locus_tag="TV186_000652"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33918..33920,aa:Thr,seq:ggt)
     gene            34484..34738
                     /locus_tag="TV186_000653"
     CDS             34484..34738
                     /locus_tag="TV186_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL1532070.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            34760..35260
                     /locus_tag="TV186_000654"
     CDS             34760..35260
                     /locus_tag="TV186_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1532071.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            35520..36104
                     /locus_tag="TV186_000655"
     CDS             35520..36104
                     /locus_tag="TV186_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1532072.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            36304..36867
                     /locus_tag="TV186_000656"
     CDS             36304..36867
                     /locus_tag="TV186_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1532073.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            36880..39531
                     /locus_tag="TV186_000657"
     CDS             36880..39531
                     /locus_tag="TV186_000657"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL1532074.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            39744..40232
                     /locus_tag="TV186_000658"
     CDS             39744..40232
                     /locus_tag="TV186_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL1532075.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(40435..41235)
                     /locus_tag="TV186_000659"
     CDS             complement(40435..41235)
                     /locus_tag="TV186_000659"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532076.1"
                     /translation="MKKKLVMSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYD
                     DYTEAPQIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDK
                     ETELVQVQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASN
                     GDKFRVHITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKE
                     REHSQKRVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
     gene            41746..41982
                     /locus_tag="TV186_000660"
     CDS             41746..41982
                     /locus_tag="TV186_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL1532077.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
     gene            41975..42673
                     /locus_tag="TV186_000661"
     CDS             41975..42673
                     /locus_tag="TV186_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL1532078.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            42873..43331
                     /locus_tag="TV186_000662"
                     /pseudo
     CDS             42873..43331
                     /locus_tag="TV186_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            43332..44306
                     /locus_tag="TV186_000663"
     CDS             43332..44306
                     /locus_tag="TV186_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1532079.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
     gene            44662..>45359
                     /locus_tag="TV186_000664"
     CDS             44662..>45359
                     /locus_tag="TV186_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL1532080.1"
                     /translation="MPNYAIILAAGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALA
                     PQKQLTVIGHQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGD
                     TPLIRGESLKALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANE
                     AEQEVKEINTGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLK
                     DFDESLGVNDRLALA"
BASE COUNT        12484 a         9069 c        10630 g        13176 t
ORIGIN      
        1 gaaaggagtg ctttcaaatg ttatcagggg agcatgatgg ctaaagagag acctcagagg
       61 aaactcagtc tttgaagcat taagacagct ttctcatatt ggttacgggt attagaaatg
      121 cgcttaatcg gtgtcaacag ttttcgtatt accatttaag acgtttcgac gacattttaa
      181 gacttaaata ctgaaagcag ctggtaatat gctatactgg tgccagttgc taaacatagg
      241 aaatattcat gtggacgaca gcattgatga aatatttaat gcttaggtac tggtagactt
      301 gcttatgttg aggctgaaaa aattaataga gtttgtgacg cagctattgg aggaataggt
      361 ggcgcactga cttgctaaga aagggcaagg tgttgtaatg cttaataaaa tgaagcgact
      421 acattatttg atgattttta ggctattaac tggtcagcta ccagctatta gcttgatggc
      481 tgttcttctt tcaaaagaca ttcataggct ttctttggga tcactgatta gttttgctat
      541 ctttgcggta agcactgctg cttctaatta ctatttttca cgagaaattg cgattgagca
      601 gttgaaggaa caaacacgtc ccaatctgtt attaactcag atcctgttta tagtggtgtt
      661 tatgattata ggcattgtgt caatctattg tggtctaagc tcgtctgagt tttataagca
      721 ggttattgct gtgatatgct cttttatatc atttgtcact atgggattga tgatttgggg
      781 gatcagatac gcaaaagctt atcgtcgtta atagcttgag gtggtactgg tacttgaaat
      841 cacctcctta accagttaat cataagctat agcactaggt atcagcctta aagcgacgat
      901 acctagtgtt tgtgtgctca aacgcttaaa atagcttttg agggggtaga gctgtctatc
      961 tgcaagcgat atgacaacct atttcattta gggatcaggc ttttttacta tcagtgtttt
     1021 tgacaaggcc cttgttttgg agtatactgg gaaaactagg agggctatta atgcgtagga
     1081 ttcgtttagc aaccttagca gatgctaagg ctttacttga tatttaccgt ccttatgttg
     1141 aggaaaccgc tgttaccttc gagtacactg tacctagctt gaccgagttt gagcgacgtc
     1201 tgtctgacat tatggtcttt tatccctgtc tagtagtgga agaggaggga ggcattttag
     1261 gttatgccta tgctagtcgc tttcatgcac gcgcagccta tgcttggtct gctgaggtga
     1321 ccatttatct ggcccaggag gctagaggga gaggcttggg atcagccttg tatcaccgtt
     1381 tggagggtta tctgaaaggt atgggaatct taaattgtaa tgcctgtatc gctagtacag
     1441 cgcatgctac gccttatctg accaatagca gtcaagtctt ccatgaaaaa ctcggttatc
     1501 ggttggttgg cagatttcat cagtcgggct ataagtttaa ccagtggttt gatatgattt
     1561 ggatggagaa actgctggga gagcatgacg tacgccctcg cccagtgatg tcatttaggg
     1621 attttctttg ccagaagcac cagtctgaat gacaccttat aaaagcttag attaatacaa
     1681 aaggattagg tcctgtcaga ggaagctaat ttttttgtat tgtttgacga gaagttttga
     1741 ctgataaccg caatcataaa aaaactcttc aggccctgtt ataaaatggt ggtagcagga
     1801 gatggttatg tctgagcttg tcactaggtc agctacagca gtcctagtgt catagcttta
     1861 aaaatgagaa aaaagaaatt attttttaag cttggtcttt ttaatatctt tttttgccct
     1921 tgacaattct gccaatgagc tgcaaaaaaa cttaagctct ttcccaaaaa gcttttatga
     1981 tatgatacac ttgtgttgta aaaggatcct gatactagtt aagatttttt tactttattt
     2041 taacaaagga gagtacacga catgaaaaga agtgtaaaat ggtttatgag ccttggcttg
     2101 gttggagctt tcgtagttgc tgggatatct aatgttaacg cagagactag gcaccctcat
     2161 ccaaagtata aggacacttg ggaatttgga attaccagtg ctagctgatc ttactcaaac
     2221 gcttttcttg gagttcctat tgggctagga agtagtgctt ctgtgacaga cttttgggga
     2281 aatgtaaata gtaaagatag tcaaaacaat ggttgggctc gtgccggtgt aaaaaagcag
     2341 tggaattggg ttcaagcaaa gtcatgttat ggctggtatc aggtttaatg ttttattgta
     2401 cgttttagtg gatgaagata ttatcctctt agtcaacttt tctcaaggag gtttttatga
     2461 ggtggagagc tacagttatc tgtattttcg ttctgctttt gacatgttta tcatttggtg
     2521 cggtcaagga gtatggcaat gatatcaaat accctgttca ggctgcattt tcattagtgg
     2581 cttcaaacaa agatgttgat aagggacacg ttttagacag gatcgaagcc ttagccgagc
     2641 aggaacatat ccaaatttat cgtccctact tagatcatac tggtaaagaa gccacctacc
     2701 tgtttgggac aaatgggaaa aagactgtct atagcagtaa tcgcaaggag ctcttgacaa
     2761 acgatcttag tggcatgtac tacacgacga ggtctcttcc ttcatcattt gaaaccgcga
     2821 tgactgaacg gggcttgacc tacaaaggtg ctgatttacc ttggtatctc ttgccttatt
     2881 attttttgtt cacaaactta cgatccttag ctatttggac cctctttttt gtgtttgccc
     2941 tcctcttgtt tgctgttaaa ttgatgtatg ctaaaaagtc tatgatacta agaagcctgg
     3001 gcttatttga acactatagc cgcaaggagt tgctacagga tttgttgctg atgggagcta
     3061 gctttgcggt tagtattctc ctcttcattc tctatcaagg cagtatctcc aatgtttttg
     3121 tcaagtcatt tacacttctg atcttgacta atgctgtcat tttattattg ctgatgcttg
     3181 ctgttcatgc tttatttttc atcaatatcc gttcgttgaa ggcgctagcc attctaaaaa
     3241 ataaacaagc aacccctttg gtcctctttg tctggttggt ggggatttgt ttgtctagcg
     3301 tcatttttgg gctttcccta cacaaaagct tggagactat aggaaaatct gccaatgaca
     3361 ttcaagttct aggaaaatgg gataaagcta aggattttgc ggaaataaca tggctagata
     3421 ccttgagtac gcatactgat gacaatcacc aaattgatag tgattatttc aaggaagaaa
     3481 atcagcgcta tcaacatttt ctcctgtctt tttctgataa tgacgttatt tattcagcac
     3541 tttcaagcct taacgaaacc aatttacaat cagctcctga tgacttcaaa aaagagttaa
     3601 agaccaatgg ggttgatcca aggattgcgt caaaagtccg ttatgtcaat cagggattta
     3661 tgctaaaaaa taaagacatt ttccctaaca atgattacgg aaggccagca gctgatgctg
     3721 taggagtcat ttatatttct aaacatatga tgggagatgc tgacagcatt ttaaacattg
     3781 tcaattatga atggtttcaa tatagcagcc taaaggctaa tcaattggtt gttcaagagg
     3841 ttcctgacgg acaaaagagc tttctgttta atcataagca agaccaacaa gacatttttg
     3901 ctcagcaaga agaagtgaat actatattag tgcagttaaa cttttcgttc atgacggagc
     3961 catcattatt gacgaagttt ggagaaatgg ctcaaaaatc tatctatcgt caggcgctta
     4021 ttcgtgatcg attaacacaa gcaggcttga cgaatttctc tagtttgacc aatgtttcca
     4081 atcatttgat tttagagcgc cataaaatcc taagccagct catcggaagt gttattgcct
     4141 taacggtcct tgccattgcc cagtgcttta tcatttatga atacattgtt tctctgatga
     4201 aacaaaaggc caaaaagatt tccgtctggt tcttgatggg gcaaaaaagc cttgttttga
     4261 ttggtagatt gttattgccc ttagctttgt gtttgtttct tgccatagga atgatgggaa
     4321 tccttactgg aaataggctc atggtactag gcattggcct gctttattta ggagaaatcg
     4381 tttgtatgtc cttttttgct tatcaggcta ttttgaagca tcggattcaa atcatcaaag
     4441 gagattttga catattatga ttgagataaa acagctttcc aaacattatg gaaaaaagac
     4501 aatttatgac aagcttagct tgacttttga ggccaatcgt tcttatgcac ttgtaggtcc
     4561 ttcaggatca ggcaagacca ccctattaaa tgctattgct cgccttgaaa agccagatag
     4621 tggtcagatt ttagtaaatg gtcaagacat ttggagcatg aaagagcaag attattttaa
     4681 ggattatttg ggctatgttt ttcaaaatta tgcactgata gaggaagaaa cagtctatga
     4741 caatcttaaa atgctggctc ctaaatctaa cattgtggaa gccttgcata gcgttggctt
     4801 agacagtagt tttctctcac agaacattta tgaattatca ggtggtcagg ctcagcgtgt
     4861 tgctattgca cgcctattgt taaaaaaggc ttgcattatt ttggcagatg agccaacggg
     4921 tgccttggac aaggaaacag gtgatgagat tattgagctg ttgcttagtt tggtgagccc
     4981 tgatactgtt ctgatttttg ccactcatga cccaaatgtg tttagccgcg ttgatgacat
     5041 catcgacatc tgtcatctac aatagaggca agctctgaga catttagtct ggactgtcga
     5101 gctacagcaa ttagcttgac aatgctgtta ttcctttgtg tcaggaagag attgctattc
     5161 ttctatagat ttttcgaata gacaatgctg aaagtcctta gcgttaatgc taaggacttt
     5221 tttgtgattt aggtcaaggt agtggtaatc tggttataga tgagctgatt cactcttttt
     5281 ccaagctagg gttaggattt cgcccttgcc aagctcagct ggtaggggtt catgctgatc
     5341 ctcttctagt aggctggtaa cccttgctgt gtggtctggg attgctaggg taagagcgca
     5401 ggccttgtca tttgatacat tatagctgcg cgtgattagg gcattatcgg ataggcgacg
     5461 cttgaaggct gtgagagcaa cgtgatcagt tgctcctttg atgtaagcat attgagctgg
     5521 cagctggcca gaatgcctct tggtttgcgc catggtgact ggtacctgag cctcctgagc
     5581 tcgccaatag ctggcaaagc gtgtggtagc gttaatgctt tcaaagctaa agctgacagt
     5641 ctgttgaccg aggcattgag catcaggggt tgggaagtag ccccaatctc caagctcacc
     5701 gacgcttcgt aggagcgtga tagcgatggt attggtatct ggtaggattt cgtattcatt
     5761 gaggccgtaa ttgcctacag tgacaccagt cctaccatca aaaaggctga caaaggcctc
     5821 ctgatgctga ggattggttg ggtttttcca gaattgggca ttggtatgat taggccgctt
     5881 tacggtttca aaaatactat ctgcaaaatg gtggtctgtc tttaaatggg ttggaaatag
     5941 cacgcgcaag cggtggtttg tcatttgatt gttaaagctg gtctgaaatt gtaggcgtgg
     6001 gctgtctttt tccatacgaa taactgttgt tactgtaaag ggcgcttttt cctgtgagcg
     6061 tttggcctga cgctctctaa tgtcaatgac agcctccatt tcagccttta gacgatcatc
     6121 tgtagctaag ggaatatcaa aggtctgtgt caattcgatt tcagcaagat aggctgtgtt
     6181 ggtcaagacc cgcaacttac agctcccttg atgagcaagg taggggctat catgatctgg
     6241 ctggcgaaag atatattcgt taccaatatc accacaatcc tcgtattgga gacagctgtc
     6301 aaacctattg ccatttagct tgtcttcaat cgttagaagg ccatttgctg cgatgatgac
     6361 ttttaggaaa tcattttcaa gacagctcct gtcctgatga aagagcattt tgtcagtgtc
     6421 agttgcttgg caaggctgat cagtctcttt tagtgcaaga cattgccatg acatagcaga
     6481 aagagtcagt gggagcctta gctgtacctt gatggcaaag taggcttctc tgaaggtgcg
     6541 ctctggcagg gcataatcaa aggcgatgtc tgtgcctaag atttcagcct cctctatgat
     6601 cctgccagct gcgtcaataa cctgaaattg tggctgtctt gtctctaggt attcctttgc
     6661 ttcttgataa acagctttag gcagtcgttg cccaaatgga aaaatcttcc atgtcagggt
     6721 gaggtcggag accgtttttt tctcatgacc gcaggtattg aagaggacaa aaggacagct
     6781 atcctctgga aacatggagg tatcaatagc ctcagctatt tggttggcag aacgctctgc
     6841 taagtaagtc cccacctcat aggctttatc aaagcgaggc atcatctcct ggtggacact
     6901 atcaacacta cagccacaaa tggagtcatg agggtggttt tgcatcaatg ttttccaagc
     6961 atagcgcagc tggtcgtgag gataggtacc tgtgacctca aaggccatcg tggcaagagg
     7021 ctctgtgata ttttcaagct gacgagacac tctggtatta gcctgcttga ggtaaattct
     7081 agcagaggca gtgttggcta aggtatacca gccgtccgtt tcttggctgg tcatctcacc
     7141 agacacaatt gagagctcct caggcagctc ctgacttaaa tcagccaaat agtcctcaaa
     7201 gcaagagtgg acaaagtcgt aatcagggta gagcttattt gcaagggcaa ttgccttggt
     7261 aacgtctagt tgaacaggct ggtgatcaac cccattcatc atcagcaggt gcctggtaga
     7321 agcaaagcgc tcagcgtctg ctagcttttg atcccagaat tgtcgagcct ttttctcctc
     7381 ggttgggatt tcgttgccat tgctgtacca attggcaaat aataagccga gaatgcggct
     7441 atcatcaggt ccctgccaga tcatttcaga aaattgggag ctgtattttt cgcttgtatc
     7501 cacttgattg ttaaagcctg taggcctgat accacgtcca aaggcagcgg catttagccc
     7561 tgcttttcgc attagctgtg gtgtttgtcc catatttccg aaggtgtctg gaaaataacc
     7621 cagtggaacg cttgcccccc attgctcaca gtcctctttg ccaaccagca tgtttcggac
     7681 attggactca ctgctggtca aaaaggcgtc ctgtaggata taaaaggggc caatacgtag
     7741 cttaccagcc tgaatggcct gtctaatctc ggcctcacgc ccaggcttga cctgcaaata
     7801 gtcatctagg ataatggttt gcccatctag atggaagcta tgaaaatcag ggtctgtttt
     7861 aaaaaggtct agtaaatcgt caattaactg gatcaagcgc atgtggtgct gctcataagc
     7921 catgtaccat tcgcgatccc aatggctgtg tgaaatgata tgtacttttt taggtgtcat
     7981 cactgactca ctttctaagg gctaatggta aagcccagat aatcaagaag aagctcacaa
     8041 aacatcatgt ttgcccatga gaaccattca cgtgtatagt gactcggatc attgacgtca
     8101 aagccctcat gcatcaggtg ggtgcctgcg tcagtagcca ccagtaaatc aagtatatct
     8161 gctttatctt tttgatcaag tgcagttaag ccctgaaggg caagtgcaat atgccaaata
     8221 tagtttggtg gcgtgtggga ggagccaata ccagaagcag cactgccttg gtaataataa
     8281 ggattttccg ggcttaaaat ggtttgacga gtggctaggt aaatagggtc gtccttggca
     8341 caaaagccaa gatagggtgc cgcaaggagg cttggaatgt tagcgtcgtc catgatagta
     8401 tagtgcccca ggccatctac ctcataggca tagatgatct ctccttggct gttggttaca
     8461 agagcatgct cctcaatccc tttttgaatg gcaagcctaa gtgcatgagc tctcctagca
     8521 atcgtttgat ccttaaagag atcagtatag agcccttcaa gataggataa gacgacagca
     8581 gcaaacatgt tggacggcac gaggtagccg tattggcagg catcatcgct tggtctaaag
     8641 ccagaccaag tcatgcctgt ataggcaaca ggagctccct taccgttgtg ggtcaaggta
     8701 tcctccttac gccaggtgtc gcgctcaaag ctgtaaggag aggcagtgtg gtcttgctct
     8761 gtgctccaga catcaaggat cagcttgatt cctctgtgga aatcctcatt gaaatgctct
     8821 gtacagtctg tctctcggta gagcagatag gctaactgga tcggatagca gagggaatca
     8881 atctcatatt ttcgttccca aatccaaggt cccatctggg tgtggtctgc ttggtggccc
     8941 ttgctatttt cctcctcgtt aaaggcgttg gcataggggt caatgcaaat gtaacggaac
     9001 tgacgtttaa cgagacctgc tatgatttgt ctcatgccag catctgtctt ggctaaaaag
     9061 agataaggct ttagttgcgc agttgaatca cgcagccaca tggcaggaat atcacccgtt
     9121 agaagaaagc tggtcccatc ttcgtcgatt tttagggtcg tttccaaggt gttggcaaag
     9181 ctggctttaa aattaatggc ccagctacgg tgctcttcac cgcagagctc ttcaatcgtg
     9241 tccataaacc tgagcacact gctaggaata ggtcttgtca tatcatatcc tcctaaaaga
     9301 tatatcattt gatatctttt ttaattataa gatataactt tatttttgtc taccacttta
     9361 gaaaaggttt acaagtcttt tttttcgtga tatactgcta gagggagtaa aaaatgactg
     9421 aattactata taaaaagata tatcatttta tcaaggaaca aattgattca gggcaattac
     9481 aggcaggtga ccgcctacca acagaaaagg ccctatcaga gcaattttcg gtgagccgca
     9541 ttacctctaa gcgagcctta gtagagctgg agcaagaggg cttgattaca cgcagcagag
     9601 gtaagggcag ctttgtgacc gatggcccac caccgtctac tcagcctaat aaggacattt
     9661 tgttgatcct gccctttgct tctgattacg aattgggaga ttatgctaaa ggaatcatga
     9721 cggtcgttgc tgacaaaggc tatcgcctga tggtccagct tacaagtacg gtaagcttgg
     9781 aggagctagc tgattatgct ggtgtgattt attatccaga agacgttaat catagtattg
     9841 agctgctctt ttattgtgcc cagcgtgggc ttgctctggt gcttttggat aaggccttag
     9901 acctgtttga ctttccagca gttgttgcag acaataaggg cggagcctat gagttgacca
     9961 agcatttgat tgatcaggat tgccgtcgga tcatgtttgt ggcaactgct tcctttggtg
    10021 aggtttcctc tgttagagat cgttatttgg gttatttggc tgcgatggcg gaaacagagc
    10081 ttgaggccaa ttattttgtg aagctgaagt cagaaagcaa tgctgcttat cttgagcgat
    10141 tggttgatga gctgacggct gctacagctg aaaagactgg tttagtggtt gaaaatgatt
    10201 ggctagccat tcaattgatc caaaaaattc tacaggtcgg gctatctatt cctgatcagg
    10261 tagctgttgt tggctttgac aacagccaag cctctcagtt aatcagccct caattgacaa
    10321 cagctgcaca ggatttttac cagatggggc agcaagcagc gcaactattg atagagcggc
    10381 tgactcggcc tgatcagcag acggcgtctt gtcagcttcc tgttaaggtc tttatcagag
    10441 aaagcagtca aaagtcccta gaaatgctat aaaaaggaga agtgtcatgt ctatttatca
    10501 agccctcaag gactatcagg aggtgataac cagaggtgat tacctcgttt ttgacgcccc
    10561 tgtttcctgt cgctttgttg gtcgtttttt ccgatttgag aaccaaacag ctatgaagcc
    10621 tagtcttaca gcgtcagtct atgtcaactg ggttgaggag ggagcagctg acttgaccct
    10681 taagcacgtt tttaaccgca ccttagctag ggatgccttt accttgacca tttcagagga
    10741 taaggagctt gtgattgaaa gccaaaattt aagaggcttt cgctatgctc aggaggcttt
    10801 agaaaaggta atgactgtta aagagggcag gctttatttg ccgattgttt cggttaggca
    10861 tagtccgtcc tttgccatgc gtggtgtgat tgaaggcttt tatggcaccc cttggacgcg
    10921 tgaggagcgt ttagattgct tgagctttat tgctgataag ggcatgaata cctacatgta
    10981 tgcccctaaa aatgatgact atcagcgcag ccactggcgt gagccctatc cagaggattg
    11041 ggtggctcat tttagggatc tgatccagct tgccaaggaa agacaggttg acttttggta
    11101 catgattagt ccggggcttg attttgacta caccaaggaa gaggactatc agctgctcta
    11161 tcaaaaattg cagcaattgt tggatttggg tgtttgtcat tttggcctgc tgcttgatga
    11221 tattgattac caaatagtgg cagcagttga gagacgtttc aaaaaaacag cctatgccca
    11281 agcacatttg gcaacagctg tttaccagtt tttacagcgg cagcatgcag cccctgactt
    11341 ggttgtctgt ccgacagagt atgataatca tcatgactct ctttatttag cagagttatc
    11401 agaggctatt cctgctgagg tggctttttt ctggactggc ccaagcactc tggccagtca
    11461 gatttctcag gcagatattg agacaatagc agccatctac cggcggccca taatcatctg
    11521 ggataatatc cctgtcaatg attatcagga cgattctaag aggctctttt tgaccccgtt
    11581 tgccaatcgc tctcctttct tgtgtcagcc agactatcag gtcaggggga ttgtgtctaa
    11641 tccaatgatt agctgggaac tatcaaagcc gactttaatt gatatgagtc gctacctgtg
    11701 ggacgccaag cgttatcagc caagctattc ttggctagag gccttgagag actatactgg
    11761 agataaggct atggctttag cgcttttgcg ctttgcttgg cataatggca atcgtcattt
    11821 gcacagggat ctcccctttg aggtggagga ggcccttatg cgtaaggaca tagctagctt
    11881 atctggttgg gtagctgagc tggtagagct ggtggataag ctgaaagagc ttgatattcc
    11941 tgcgtttcaa caggctattg ctccttggtt tgatcgggct aaggctgatc agagcttttg
    12001 gagggttatt ttagagcaag cgcctgatct tgagcagcaa tatgctgagc ttcaggagca
    12061 aaggcatcga attggaagca atattccaag ccgcttttat cagttgcact atcttcagga
    12121 gaatagcatg ctaggcaatc aggcacaggt cgctgaagct agagctgagg attatactta
    12181 attagtttat aagggagaac aagggacatg ctagagtttc cagaaggatt ttggtgggga
    12241 agtgctacat caggccctca aagtgaaggc tgctttcaaa agccgcatcg caatttattt
    12301 gattattggt atgagcaaaa tcctgagctg ttttatgatt atgttggacc tgatacggct
    12361 tctgattttt ttcatcagta tgatcaagac ctagctttat tagcgtcttt gggtcacaat
    12421 tcctatcgga cctctatcca gtggacacgc ttaattgatg attttgagac agccacgatc
    12481 aatcccgatg gactggctta ctataacagg gtgattgatg cctgcctagc acatggtatg
    12541 cgtccggtga tcaatttgca ccattttgat ttgccaattg ctctttatca gaaatatggc
    12601 ggttgggaat caaagcatgt tgtggatttg tttgttgcct ttgctagagt atgctttgag
    12661 cagtttggcg atcgcgttaa ggattggttt gtacacaatg agcccatggt tgtggtggag
    12721 ggctcatacc tgctgcaatt ccactaccct gccattgttg atgggaaaaa agcggtacag
    12781 gtggcttata atctagcact tgcaacggct aaggttatct gtacctacca agaacaagca
    12841 gcagagctga gcaatggcag tgttggtacc attctcaatc tgacaccgat ctatccggca
    12901 actgattcag aggctgatct tgctgctgct catgttgcag agctgtggca caatgacctc
    12961 tttatgtctg ctgctgttta cggtagcttt ccaaaggagc tggtagcaat actacaaaga
    13021 gatggagtgc tctggcagtc cacaccagag gagctggatc ttatggctgc ttatacggtt
    13081 gattacgtgg gcattaattt ttaccgccct aagcgcgtga aggcgccaga ggttattcct
    13141 gtgattagcc cttcctggag tcctgagtgg tattatgatg cctatctgat gccgcagcgt
    13201 cgtatgaatg tggacaaggg ctgggagatt tatccagagg cggtctatga tattgctcta
    13261 aaaatgcgtg atcagtatag gaatatccct tggtttttat ctgaaaatgg ggttgggatt
    13321 tcaggagagg atcgttaccg agatgagagc ggacagattc aagacgacta tcgcattcag
    13381 tttttaaaag agcacctgac ctatcttcat aaggggattc aagcgggctc taattgcttt
    13441 ggctatcatg tttggacacc tattaattgc tggtcttggc taaatgccta taaaaaccgt
    13501 tatggtctgg tagaaaataa tcaccgcact cagcgtcggc gtgtgaaaaa atcagggtat
    13561 tggtttaagg aggtggcaga ggcaaatgga attagctaag aaaagaagaa aaacacaaaa
    13621 gccagcccaa tctcctttaa agctaggttt agagaagcta agagagattt tacaggagca
    13681 gctagtagct ttagcggttt tacctgctag ggtgatgggt tagcataagg gcttgctgat
    13741 gagctatgcc agtgatagcg attaaggaat gtaaaagagg atttcctaac atcataacta
    13801 tccgtctaac gggtgattta ttgtttcgta cctacggagc gaaacggact aaagtcacat
    13861 aactaaaagc atgtcatggc ttgctgtagt acgagtgatg acatgctttt tttagctttt
    13921 aacgggttag ggagtagggc aggtcctcag ccgaatagtg cttgagtggg ggaactagtc
    13981 ccagctgaaa gtcgagctga cagccctgaa tcagatcatc atgattgatg tagagcttgt
    14041 tgtagctagc ctgattgagc ttgacctctt tgacaaattg gtattgaggg acattgcccc
    14101 tacagctgat ttggatagta ttgccatttg gcagataaag ggttgcctga tctacagttg
    14161 gaataccaat caggtattgc ccagttcctg gtgtaacagg gtaaaggcca aggctgttta
    14221 acaggtacca cgcgctcata ctgccattgt cctcatctcc tgggtagcct gtatcggtaa
    14281 aggcatgact gagcagattt ttaaggatta gctgactgta ttgtggctga ccgatatagt
    14341 gatagagata ggggaggtga aagcttggct gatttgagat agcaatctga ccaaaatcct
    14401 gtgcggctag ctcactcatt tcgtggattt caaagccata gctgtgaacg tcaaacacag
    14461 gctcatgatt gcacagctcc tcaagtcttt tggcaatggc ggcgtttcct ccgatcagtc
    14521 gaatgtaacc tagaatatca tgataaaagg caaatccatt ttgataatag gagccctcgg
    14581 tgtagtcctg cccccagtgg atagggttaa agccacattg ccattgccct tgtcgatcct
    14641 tgcttttgag gtagccggta tcagtatcga ccaaatggcg gtaattgagt gatcgcgtgt
    14701 ggtattggtc actaagtgct gtcttgccca gaagggcagc tacctggccg atacaaaaat
    14761 cactataagc ataatcttga gtctgattga cgctttcctg gtagctattt ggcagatagc
    14821 ctagctcttg atagtcttga ttgcccttgc ggccatagcc tgttccttga ctgtctgtat
    14881 tggcagttgc cagcatagcc tctaaaagct caggcatcag gtcttttctg atgcctttga
    14941 cagctccatc agcaataaca gcatcaacca aggttccagg catcaggcct cgctcatctg
    15001 gagacagcca ttttggcaga tagttggtgt cctgataagc tgacaagagt ccctctaaaa
    15061 tatcagcata aatctcaggt gcaattagag acagcaaagg atagacagat ttataagtat
    15121 cccaaaagcc attgttggta tagtattttc cagcaacagg tctttgactt gttgtattat
    15181 agtgaatcgc ctgcccggtt gcagtgattt cataccatct ttggggaaat agcagggctc
    15241 ggtaaaaatg ctggtagtag gccttgacct tatcaaagtc tttatcctta atgtcaatac
    15301 gactgaggta gctgagccac tccttgcggc tgtattcaag gcttttttca aatgatctgg
    15361 ggaaatccct ctgccaattg agctgagctt gatcaaagct aataaaagaa gcagccgccc
    15421 taagctcaag atgtttgagg tcatcagcaa attggagata ggtaaaggac gtcttgctgc
    15481 aatcatcaag agatttggag tttaagtctt ctccgataag cttttttagc acagggctgc
    15541 taaactgaag ataaacaaac atggctaggt ctttatcctg acagtctgtg atgttttgca
    15601 cacagccaag gattgtttta ccatcagctg tcacctgcca ggagcttttt ccggggttat
    15661 ggataatcaa gcctgctttg ccattatcaa aggaaaaatc acaatgaaag ctgtaggcag
    15721 ctgctgttgc tcgcgtcaaa atccgatgtc tctggctaaa aatctcaaga agatgaggcc
    15781 gaaaagctgc ctccttggga cgataggagg tctgattatg aaacacatct cccttggtca
    15841 gcggtccgct gactggaaga aaagtaaccg tcgcaaaatc accgacccaa gggctgggtt
    15901 gatgtgtcaa gcgaatacct gaaaagctgt gatcatcggg gtgaaaccac caagcccctc
    15961 gatcttgact ggtttcgacg cttagataat gcatgccaaa gggaacccct gtcaatggca
    16021 ggcaatttcc ctgtgaaaaa tggtagtgat tggttgttcc aaagcgggtg tcaatgaagt
    16081 ctaatcgatc cacatctcgt cctttctatg ctcttgcata aaatcaatag aggcacctag
    16141 taggttggcc tcgtttttaa agtggcagat agcaagctgc ggtctcaaat cagaaatgct
    16201 gactatctga tagagcttat ccagttcagc ctcaagggca ggaagaagaa agtcagcctg
    16261 agagacaccg ccaccaatta ggatcatttc aggatcaaag gcatgctgga tattaaacac
    16321 ccccattgcc agactttgaa gaaagacctg tctttccttt agggccacag gatctccttg
    16381 atcagctagc tctaagacct ctttaccggt gtaactttta ccatcattta tgatctgact
    16441 atagcgcttg gccatattga ccacagtgcc taattcgctg aaggtttgat aacgctcatt
    16501 catgaccata aagccaaact cacctccaaa taaatgggca ccgtaatgaa tcctgccatt
    16561 aatcactagg ctacctccaa caccggtgcc aagtaccagc atggcaaggc tgctagtgcc
    16621 ttgtcctgca cctagagcag attcggcaag agcagcacag ttggcatcat tttcaatcga
    16681 aaccggcaga cctagtcgct cctcaaggca ttgctgaatg ggaaagccat gaatataagg
    16741 cagtgcactt gctccctcga tgatacctgt tgctttattg acagctccag gggagctaat
    16801 ggcaattcct gagagctttt ctgtgcggta gtaagccagt cgctcgtcaa gcatatggta
    16861 aaagtcctct aggctttggg gagttgggcg actgctttgc ttttttagcc tgcccttgtg
    16921 acaaatagca aatttgatgc tggtgccgcc tatgtcgata cataataagg tcattgtaat
    16981 tcctcctata acaggtatat taccaattag ctacccttag tatgacagat tttgaagtgc
    17041 ttgaaaagac tttctcggca ttcctatatt ttgtgctatg atacctataa tttgtgttat
    17101 caaacctata atttgttgct tgttctatgt gtaagcgctt gatatacttg aagcatcaat
    17161 tgaaaagcaa agggaggttg ggaagatgac gacaaagatc agcagcaaga aatccttttg
    17221 gaaaaatgtg atcaaatacc gcgctttgtt gctgatggta ttaccgggat ttgtctggtt
    17281 catctttttc ttttacattc cagtattagc taatgtagtg gcttttaagg attttcatta
    17341 ctcagcagga ggttttatgg aaagcctgaa agaaagtccc tgggttggct tagataactt
    17401 taaatacctt tttgcctcta aggatgcttg gttgattacg cgaaatacca ttgcttataa
    17461 tcttattttt ttactattta acgtcttttt tgccatcgct ttcgctatta tcatgagtga
    17521 gcttcgaaac aagaaggctg ttaaggtcta tcataccatg tccttactgc cttatttctt
    17581 atcatgggtt gtgattgagt attttgtttc tgccttttta aatacggata agggctttat
    17641 taatcagctg ctcattgata gcggcaatag cccaatcaaa tggtattcca atcccacctg
    17701 gtggcccttg attttacttt tcatgagtgt ttggaaagga cttggctaca acagtatcat
    17761 ttattacgca tcggttaagg gaatatcaga cacctactat gaggcggcta tggttgatgg
    17821 tgccagtaag tggcagcaaa ttagacatat caccattcca cagcttttgc cgatgatgtc
    17881 tatcctattg attattaata ttgggagtat cttcaaatct gactttggct tgttttatgt
    17941 gattcctaaa aattcaggtc ctctttacga tgttaccagt gttttagata cctatgtcta
    18001 caatgccctg acagctactg gtgatattag tatggcttct gcggccagtc tttatcaatc
    18061 tgtggtcgga acctgtatcc tgctcatcac caatgctttt gttcgtcgta tggatcccga
    18121 tgcagcctta ttttaggagg aggacatgga gaaaaagaaa actgttaaaa gggtcaacgt
    18181 cagaaccttt gacccaaaaa ccaatgctgt ctttaatgtg ttaatcgctc tttttgccat
    18241 ctcttgtatc attcctttta tctttgtgat gattatttcc ttcacagatg aaagctatct
    18301 gatcaatcat ggctatagct ttttcccagc tgcttggtcg acaaaggctt atcattatat
    18361 tttccaaggg gctatgtctc atcggatcat aagatcgttt gcggtgtctg tatttatcac
    18421 cgttttagga acctttatca ataccacaat gacctcaacc tatgcttatg ccatctcaag
    18481 accttatttt ccctacaggc gtttttttac catctatgcc ttgatcacca tgctttttgc
    18541 accgggtatg gtagccaatt atttggtggt gagtaacctg ctgcaattaa aggatacggt
    18601 ttgggccttg attttaccga tggctctggg accctttggc attttggtga tgaggacctt
    18661 ctttaaaaag accgttcctg atagtattat tgaatccgct cgtatggacg gcgcaggtga
    18721 attgatgatt tttatgaaaa tcgttttacc tttggcagtt cctgggattg caaccattag
    18781 cctgttctca gccttaacct attggaatga ttggttcaat gcgctgctct atgtgcaaag
    18841 cgagagcctt tacccgatgc aatacctctt gatgaagatt caaagcaata tacaggcact
    18901 agcccaaaat gctggcatga gcgcccagct atctgatagc ttagcctctt taccaaagga
    18961 atctgtccgc atggctattg ttgtcattgc aactttgccg atcgccctaa cctatccttt
    19021 ctttcaaaaa tactttgttg gaggactaac catcggcggg gttaaggaat aatcacccat
    19081 ttggaatagg tcatacagct gaccgttcca atgattctgt tatcaaaaaa agaaattatt
    19141 ttaggaggct tactgatgaa aaagtggcaa acaatcttat gtgtgacggg agctgtgctt
    19201 gcagctgcta gcttgacagc ctgtggaagc aaatcagctt ctaaggacgg tgaggtgaag
    19261 ctattgatgt atcaggtggg agataagcct gataactttg atgagctgat gacaattgca
    19321 aataaacgta ttaaggaaaa aacaggggca acccttgatt tgcaatacat tggctggggt
    19381 gattgggacg acaagatgag gatcattatt gcgtcaggtg aaaattacga cattgccttt
    19441 gccaacaatt atgtggtcaa tgctcaaaag ggtgcctttg ctgatttgac taagctaatg
    19501 ccaaaatacg ccaagaaaac ctataagaac ctagatccgg cctacattaa aggaaatacc
    19561 attgacggta agctttatgc ctttccagta gatgctaacg tctatgctca gcaaatgctg
    19621 tctttcaaca aagaattggt agacaaatat ggccttgaca tttcaaacat caattcctat
    19681 gcagatgctg aaaaggtctt gaaacaattc cacgaaaaag aacctaatac tgctgccttt
    19741 gcgattggtc aagtctttag catgtcaggt gactacgatt acccattgac caaaaatcaa
    19801 ccatttgctg ttaaaatcga tgaaggcaaa ccaaccatca ttaatcagta cgaagatgag
    19861 ccctttaaag caaacctacg cttgatgcat aaatggtata aggaaggctt gattccaaca
    19921 gatgcagcaa ccaacacaga aggctacccg cttgaaggca atacctggtt catgcgtgaa
    19981 gaaacccaag gtcctatgga ctatggcgat accatcttga ccaatgctgc tggtaaagac
    20041 attgtgtcac gaccattgac aaagcctctt aaaacgacct cacaagccca aatggctaac
    20101 tttgtcgtgt caaatgtgtc taaaaataaa gaaaaggccg ttgaagttct ttcccttctt
    20161 aacagcgacc cagaattgct aaatggtctt gtttatggtg ttgaaggcaa ggcctgggaa
    20221 aaggttggcg acaagaaaat caagctgctt gatggctacc aacccaaaat gcacatgggt
    20281 gcttggaaca ctggtaacaa caagatcctc tacacccaag aatcgatcac agatgatatg
    20341 attgcaaagc gtgaccaatc aatcaaagac gctaaagagt ctccgatcct aggctttacg
    20401 gtagatacca aggcaatcaa aacggagcta tcaaaaatct caaacgtgat gaaccgttat
    20461 aaagctagta tcaatactgg tacagtagac cctgatgaag ctcttccaaa acttctttca
    20521 gaccttaagg acgctggttg ggacaaggtt caaaaggaag tgcaaaagca attggacgac
    20581 tttgttacaa aaaataaata aggcaatgga ctttccttgc aaggtggtaa gaactgggga
    20641 cagcctcagt tctttttagc tcaagcaggc atacaagagc tgacagataa ggcctctctt
    20701 agaaaaaagc cagagcctgc ttgcaaggca gttggtccac caaagccctt gctgacaagg
    20761 ttttaccagc cttagtcggc tgtcctcttt ttattaagct tttgtcacaa ttagagtaaa
    20821 atatgctata ttagaagtat ctcatcttat catcatgaca gctaagacct tagtcatctg
    20881 gctgagggat cgttgcttct cttagggcgc tattggtcct acaaaggata ctagaaaagg
    20941 ataatcttat gacaggaatt gaaaaagcct gctttctcat ctggaaaatg atgcagctaa
    21001 cccttatatt tcatttgctt tccttatgtg gtgctgtgat ttttggagtg gggccagctt
    21061 ggcagaccat tgttaccttg tttttggaga ccagtcagca ggagaaacat tattcgctca
    21121 agcgggcctt tcagatatgg cgtcgggtct tcaaagaggc caatctcagc tttttcttct
    21181 ttggattatt gctattattg ctgaatacga gcctgtactt ggccattcaa tttcaatcgc
    21241 tgctgtggtt tagcctatcc tttattatca tgtttgtcat ggtttggctg gtgatgattg
    21301 tgatttacat gaccttttat gcagtgacct atgaaattgc tttttgggag aatctcaagc
    21361 tgtcttttat cagtattttc ttgaatgcca ggcagttttt gttgaccctt gtggttttag
    21421 ctggagttgc ttggtttact tggcagtata agggcttgta tctttttctg agctttggtg
    21481 cgctggtttt gttgctggat atggtcacca agcctaatcg tcgcatggta gatggagtca
    21541 ttgatgacaa gtaaatcttt aaagcggttc ttgatggagc atattaagca gggcttttta
    21601 attaaccgct tgatgaaaat atatagcctg tttatcgtgg ctctctttag cttaagtgcg
    21661 gttggtctaa gcacctattc gattcgaaat acctaccaaa tggttgacaa tcaaatgcaa
    21721 atgcggctag atgagaccct agcaaggcta caatctcaaa actatattac cctgcgcgtg
    21781 ctggagcagc tgatcgggcg tccagaggat tatcgaaatc tgtatcagta catgatattg
    21841 acccctaatc aatatcttac taaggttttt gaggattggg gtgagggcaa aaacacacct
    21901 ctgttttcag agcaggtcag aaggcttttt gatttgtatc cagatttaga tgggctgacc
    21961 ctgatgctgg acgatagcac gtcctatttg tatgcagata ggtcgattaa gaccggccgg
    22021 ctcttatttg gtaagcctca gacgctaaag ggcaattact tagtaaggtc cattcgccac
    22081 cctgagtcag gtgatgttac aggccgcctc tatctgcact ttgcaagccc cagcacgatg
    22141 ctacagcctg agcagcataa gtatctagcg acctttgcct ttgattacta tggcagagag
    22201 ctctttcatc agggaggcgc tgcctttccg gagcttgaag caggtcttaa aaaggcgcta
    22261 aaggcggatc aggctattga tttgacagct ctcagcaaga gctatcatat tcagtacaat
    22321 cgctcgggag acttgctggc ctatgtggcg gtcaaaaggt cttattttat ggaagaggct
    22381 gtgcgtacaa tgctcctgta tggccttggc tcgttattgc tagcttggtt attgctacag
    22441 ctccttttca gggtatttcg caattatatc cgacaggtct ctgagattac agatactatt
    22501 gaaatggttg cagctggtga tttgtcgtta aggattgaca acagtcatat ggaattagag
    22561 ctgtatcaca tttctgaggc gatcaatcaa atgcttggca acatcaatgc ctacatttta
    22621 gaaatctatg tccttgaggt tgagcaaaga gatgcccaga tgcgtgcctt gtcatcacaa
    22681 atcaatcctc attttttgta taacacccta gaatatattc gcatgtatgc gcttagctgt
    22741 cagcaggagg aattggcaga tgtgatttat gcctttgccg ctttacttcg aaataacatc
    22801 agccaggata aggtaaccac tctaaaagaa gagctggctt tttgtgaaaa gtacatctat
    22861 ctgtatcaaa tgcgctatcc agatagcttt gcctaccatg tcaagcttga tcctgtcgtg
    22921 gctgatgtgg aaattcctaa gtttatcatt cagcccttgg tggaaaatta ttttgtgcat
    22981 gggattgatt acagccgcta tgataacgcc cttagcatca aggcgctaga tgaggaggac
    23041 agtattttga ttcaggtgct tgataatggc aagggtatta gccctgagcg cttagtggct
    23101 attgaaaagg gcttagagga gccgcaatcg acggggaata gctctattgg gctgcaaaat
    23161 gtctatatgc gcctatttca caaatatcga gacagagtga cttggtccat gtctcaggca
    23221 ccgactggtg gctttaggat tcagatcaga attagaaagg aagcttaatg tacaaggtct
    23281 tattagttga tgacgaatac atgattttac agggcctaaa ggtgattatt gactggcagg
    23341 cgcttggctt tgaggttgtg gcaacggcaa ggtcagccaa agaagcctta gcttacctag
    23401 atgactgcgc tgtagatgtc atgatttcag atgtcaatat gcctggtatg acaggcctgg
    23461 aattgattga ggcagcaaga gatgtattgc cgcatttgca gaccttgatt ttatcaggct
    23521 atcaggaatt ttcctatgtg caaagggcta tggagctaga gactaagggc tacctcctaa
    23581 agccagttga taaaaaagag ctggtagcta aaatgctcta ttttaaggaa tggcttgatg
    23641 agcagagggc agcttctttg cgtcaggctg cttatcgtga gggcttgata aatctctggc
    23701 ttgctgatga attgagtgag aaagagtttt ttcaactaac gcaggagcaa cccgaggctg
    23761 agcttttagg ctttacggtg ttgtatgtgg attgcaagac ttttagccct gccttagaag
    23821 ccttttttga ggcctccaag cagccctttt acttaaaaaa ggcagagcaa aagaaggtct
    23881 atctagtcat tctattagga cagagccatc aggctaagcg ctttactaat acgcttcagg
    23941 agcgatttta caataccatc aatcagatca ttctaggaga aacggttgtt gattgggaaa
    24001 atgtgtatga aagctataat caggtcagaa ggagcttttt ttacaacagc gaggtgtctc
    24061 aggtagctgc taagaccaac gctaaaattg agctgccgga atcgcgattg cagttttttt
    24121 cctttaacaa gaccttgatg attggggacg agccaactat tgtctccaaa ttacaggcaa
    24181 tctttgagga gatgacagag ctaagcttct ctcctgagga cgtcaagcac gtctcttttc
    24241 tcttattttc agacatttat cgccaatttc cgattttaga tcgaacgacc tacctatcga
    24301 tggtcaagac tattcacgat agtcagtcca ttgatcagat cttatcagcc ttaaaaaagg
    24361 tgcttgagct gacaagcaaa agcaatcagc cccaaaagcg ctattctgat ctggtcagtg
    24421 aagccattac ctgtattcag gaggaatact ctcaggaatt aaccctcaag gctgtgtcag
    24481 atcgcttgca tatcaatggg gtttatttgg gacaacgctt taaaaatgaa acagagtgta
    24541 gtttttccca atacctcaat caggtgagga tccaaaaggc acagcaattg ctgctttaca
    24601 ccaataaatc gattaacgaa attgcctatg agacaggcta taatactaac cattatttca
    24661 taaaaatgtt caaaaaatta aatggtttat cgcccaagga gtttagagac cgttataaag
    24721 ataattatca agctataaaa ggaagctatt aagaaagggg gcgctatgtc tgtagagaca
    24781 atcactggtt caacggatca atctcatggg gatatctatc agcttcactg gattgataaa
    24841 gtagggcgct gccatgcctt ttcaaagggg tggcgctttc tgatggctga tttgcagctc
    24901 gctcaggagc cattttttga tgattcggac tggcagcaga tagctttacc acatgatttt
    24961 agcattaatc agccctatac ggttaatggc gaagctcaaa gtgcctataa gctaggtggt
    25021 gtaggctggt accggaagta ttttgccctt gatccaaagc tggctgacca taaggtctat
    25081 gtgacctttg atggggctta tatggaaacg caggtatacc ttaatgggca tttgatagga
    25141 gagcatgtca atggctatca ggcctttagc tatgatctct cagcctttgt aatccctggg
    25201 caagagaatc tattagcggt tcgggttgaa catctggtgc ctagctcgcg ttggtattct
    25261 ggaagtgggc tttatcggga ggcttttttg accgttcttc cgaaggttca tcttgataag
    25321 gatcggcttc gtttatcctt atcccaggca gcgcttgagg ctgatagcca agcgcttgag
    25381 atagagcttg gactcagcca acaggtcccc ttgagtggct atcagcttag ccttagtctg
    25441 tttgagcagc tggcagatat ccagcagaga cagacagtat atgagagtaa accggtagcc
    25501 ttggacctct tggaggagtc aggtaggctg gtgatgacca ttcctcttag gcatatcaaa
    25561 ctgtggtcgc cagctcagcc ccagctctat cagcttgata tgcttcttta ccataaggga
    25621 gcagtgcttg atcggctgac acttgaaaca ggctttcgac agctgcattt tgatgctgag
    25681 tgtggtttct ttttgaatgg caaagccttt aagctgcaag gggtctgtct tcatcatgat
    25741 cagggtagcc tgggggcatg tgcttatgag gaagctatag ctaggcagct tgttttgcta
    25801 aaggaaatgg gagcaaatac ggttcgtgtc acgcacaacc ctagtgccag aaggcttaag
    25861 gatctggcta acaggcttgg gttatttctc attgaggaag cctttgatac ctggacttat
    25921 gctaaaaacg gtaatagcca tgatttttca agccattttc acaagacagt gggacaccaa
    25981 aatgcagcca ggctaaaggg agtcactaca gcagaaacca cctgggcgca atatagcata
    26041 caggccatgg ttctctcagg tcttcatgat ccatctgtct tgatgtggtc aatcggcaat
    26101 gaattgttag aaggcttctc agctgatgtg agccactacc cttatgttgc taaggagcta
    26161 tgccagtgga tcactgagct ggatcagtca agacctatta cccttgggga taataagctc
    26221 aaggacaagc attttcattg ggcgcaggaa acaaaagcgt tggcagagca ggtcaatcag
    26281 ctccagtccg tgcaaggagt gattggactt aactatgcta aggccagaga ttatgatcga
    26341 ttgcataggg acaacccgac ttggctgctt tatggctcag agacagcctc tgctattaat
    26401 agtagagggg tctatcatct caagggagga gctagtcagg atcatgagct aacctcctat
    26461 gaccagtcaa cggttgactg gggatcctta gctagtgagg cttggtatga tacaatcaca
    26521 agggattttg ttgcaggtga gtgtgtttgg acgggctttg attatctagg ggagcctact
    26581 ccttggaaca agattgactc aggcgcagct gatcagtggc cgtcgcccaa gcaatcctac
    26641 tttggtattt tagatactgc tggatttgct aaggatagct attatttcta ccaaagccaa
    26701 tggtcaaaag acaaaacgac acttcatatc ctgcccagct ggcaggaaaa agaccttcag
    26761 ctagatgatc agggcatggt ggaggttgtg gtttatagta atgctgctag tgtgagaata
    26821 ctttttgatg atggtcatgg gggccagatt gattatggca tcaagaccct gacaaggcat
    26881 gaaacaccag caggccattg ctaccagcta tatgagggtg acgatgcagc agaattacct
    26941 catcaaaacc tttacctgac atggaagctt ccttatcgct caggcagctt gagagctatt
    27001 gcttatgacg acaagggaca ggtgctcaca cagaccagcg gtcgttcctg tgtgagcagc
    27061 taccagcagc ctgctcagct ttcctggtcc tgctttgagc ctcctaaact gcttgcagag
    27121 cctgcgctac tttatcttga attgtctttg ttagatgcta atgagacctt ggtgctcagt
    27181 gctaatcctg tgattaagct tgaggttgag ggtcctggag cctgccttgc tctggataat
    27241 ggcgatcctc gtgaccatag gccctatact gccttgtcac gccgagcata tggtggcaag
    27301 ctattagcca ttattgctct tgatggtcgt gcgggtcagc ttagaataac agctagagcc
    27361 gcaggattcg tggaagccag ctatcagttg acggtttctg aagcagccgt taatgagaag
    27421 cttttagcct atcagcttga taaatacagc tttatcacta atgagacaaa taagcctagc
    27481 aagccctatg caaggtcaag aggatcagct gttgatagct taatgcctaa tcctgatagc
    27541 tgcttaaagc ggcaaggcca ttatctgcct gataattctg taatggtttt tagctataca
    27601 acagcattat caaggccact gacctttcag ccactgatca aaaggctgct aaagggcaat
    27661 gatatcattc taccagactg gctgcagcct agggcagctg ctggccagtt atttaccaag
    27721 gcttttccta ttgattggca gctaacagag gcagtttttt ctgaggagtc aagggttagt
    27781 gggcagaccc tttgttttgg agaggctttg gagcttgaag ctatccttaa gtcagataca
    27841 aaaggattaa ggatcaatca agagcttagc ttagttgcta aaaagaagcg gctgtttcag
    27901 agtgataccc agcttagcta ccgctatcaa tacgatacca tacaggccat tggtgccatt
    27961 agcctgacag gactaaagaa gcccttaagc tcgcttaggc ttgttttgga ctatcgcagc
    28021 agcaccaatg cgccatcaaa acagctgatc ctatcgcttg atcagataga acagccctgt
    28081 cactacatca tgctggaaga agtagttgat gtgctaagcc tggacctaac attagagcag
    28141 ccgatcagac aggcttttga cttagctagg cttcagctag gcctttggag catggttgag
    28201 gaggcttagg cttcaagctt atcggctcat actgtcaata ggattgagct gagacagtct
    28261 ttgaaaaata aggtataatg acagtaaatg cctagcaagc tttgctaggt tagcaaaaaa
    28321 taagcatcgc ctgatatgat gtaaaggagg aggtatttga tgctagagcg tttatcaggt
    28381 cagacacgat taacagcttt gctggcagca ccggcacgtc acagcctatc accgaaaatg
    28441 cacaatgcag cttatgctaa gctggggctg gattatgcct acctagcctt tgaggttggt
    28501 aatgctgagc tagctgctgc tgttcagggc atgcgtgcct tgggtatttg cggtgcaaat
    28561 gtgtccatgc caaataagca ggccattgtc ccattgcttg atgagctatc accggctgca
    28621 gccttagctg gagctgttaa tacggttgtt aataaagatg gcagaggtca tcttgttggt
    28681 catatcaccg atggcacagg tgctattcga gccttagcag aagaaggggt ctcgataaag
    28741 gatcagatca ttacgattgc cggtgcaggc ggtgcaggca cagccattgc tgttcaactg
    28801 ggacttgatg gcgccaagga gattcgacta tttaatcgga aaacagctac ctttaagcag
    28861 gccaagcagc tggttgctag aattaatacc caaacctcag ccctggcaag ccttcaggat
    28921 ttagcggatg atcgagcctt taggcggtct atttcagagt ctagcattta tattgacgcg
    28981 actggtgtag gcatgaagcc ttttgaggag catcgcctga ttactgatcc agctcttatt
    29041 cgcccagatc ttgtggtttt tgaccttgtt tatcacccgg cagaaacaaa gctcttagcc
    29101 tttgcgcgtg agcatggggc taaaaaagtg atgaatggcc taggcatgct cctttaccaa
    29161 ggagcagaag cctttaagct gatgacaggt gaagacatgc cggtagccta tatccgagag
    29221 cttttatgtc agaacaagga atgaacgcct gctgctcacg ccggtatagg aaaaagaaaa
    29281 aaaggttaat tgctcagctc tttgattggt cttgaggttt gtcggcattt tatttataat
    29341 aaaaagcacc aaaagcaaag gagcagccta tgatattgac acaatttgac cctgactacc
    29401 aagctatcat taaccctaag gaccttgtag cagaaataga tgactttcct aaaacagtag
    29461 tcacctgctt tgcaagagca acctttaata gggtacttaa tgcactgcca catcgactga
    29521 tagccacaac aagcgttgct aatcttgata ttccaatata cgaattagat gttaaagggc
    29581 ataagcttgg ctttttcaat tcctacgttg gagcagctgg ctgcgttggg gttttagagg
    29641 atatcattgc tatgggaatg aagcagctct tggtttttgg gacctgtgga gtcttagacg
    29701 ctactatcag tgaaaactct attattattc caactagtgc tattcgagac gaagggacca
    29761 gctaccacta tcagcctgct agtcatgaca ttgcagtgaa tcaagcttat ttaacaaggg
    29821 ctattgatgt tttagaacag cattcccaga cctataccct tggtaagacc tggacaacag
    29881 atggcattta tagagaaacc agagacaaga tgattcaacg aaagcaggaa ggggctattt
    29941 gtgttgacat ggaatgctct gcgattgctg ccctagcagc tttcagacag ctagagcatt
    30001 ttcagttttt ttattccgct gataatctag atgctgatga atgggacgca agaagcttag
    30061 ccaatgaagc agacctagaa gccaaggata acattgcctt tattgcctta gagttggcct
    30121 tacgattatt taaggataat taaaaaagca ccaagagcta tgaagtgcct ccaaaaggtt
    30181 agattaaggc tctaacgcct gggagatcag ttcagctcaa ggtgcttttt aggtgtcatg
    30241 cagacagctc acctctgcat gtcaatataa tgtttagagt agcctatgct tcttatacct
    30301 atgccttagc attcacctag ggacaaagca atgaagctta ggcctttcac cttactgtga
    30361 aaaaagtggt cttttctcat caaaagactc agtaaacaag aggctttgaa gcctttttgt
    30421 ttttcagaag cagcagtttt ttcactcgac taataagaca ggagaaaagc cttctcaggc
    30481 gatatctagc aggcttctta gccaatccag caggcgactg tcatgcttag caataggaaa
    30541 gcttacatag ccttttgtcg ttggcaaaat gaggacaata tgctgaccag aatttttctt
    30601 atctgttttt aaaacagtca tcaaggcttc ggctgtcatt gacttagcct caagtgtggt
    30661 aggtagctga taagcctcaa aggcagcctg taatgcctct aaatcctgtt ggctcaatag
    30721 ctgctgctgg acggccagct tggcctcaaa gaccatgcca atcgcaatag cctcaccatg
    30781 cctgtaaagc tcgtgatggc ataaggcttc aatcgcatgc cctagcgtat gcccgaaatt
    30841 taaggacatg cggagattgc cttcaaattc atccttttca accactcttt ttttatggca
    30901 aatcgcttga aaaatcattt gcctgagctg ctcttgattg cggtccttgg ggaaggctag
    30961 gagctgttga aagagcttgc gatcatgaat aaaaccaatt ttaatcattt cgctgatgcc
    31021 gcaggcaaat tctctttcag aaagcgtgtc taaaaacttg gctgacacga taatctggtt
    31081 tggagggtag atactgccta tcatattggt caagccctta aagtgaaccc caaccttacc
    31141 accaatgctg ctgtctacct gactaagtaa ggttgttgga atctgaacgt aggaaatccc
    31201 gcggtaaaag gttgccgcaa caaatccccc aagatctcca atcacccctc ctccaacagt
    31261 aacaatgacg tcctttttag aaaaattagc cctaatcagt cgatcgtaaa tccgactaac
    31321 ctcctctaga gacttagatt gcccccctgg agcagcaata tgaaggtaac tatcgtaatc
    31381 ctgttgaaaa cgtctaaata aaggctggta taaatcaaat accgtttgat cagtgataaa
    31441 taatagcttg acgtctcctt tttcagcaag aaattgattc agcggctgaa aaatatcgtc
    31501 tgtaaagata atcggatagt cattgatacg agacttaacc tgaagtgttt gtgtcatgcg
    31561 tctttctctc ctaagcacca ttagttcaaa tgactggacc tgtggctgct gttagttagc
    31621 tttcccaaag ctcttttcca agctgctcta gctgttgata atcaatctgc tgcgcggcat
    31681 ctgacaaggc aagatcaggt gtagggtgca cctccatcat aataccattg gcaccgatag
    31741 ccttagcggc cttagccgca ggcaatagta aatctcttct tcctgttgag tgagagacat
    31801 caacaatgat tggcagcttc accttttgct gaataatagg gactgccatg atgtctagca
    31861 tatttctagt ttccacatca tagccacgaa ccccacgctc gcataaaata atattttgct
    31921 tgccattttc ttgtaaataa gataaagcac ccaaatattc ctcaatggtt gccattagtc
    31981 ctcgtttaaa caagataggc ttgtcaatct ttgacaatac ctttaacagt tcaaaatttt
    32041 gcatatttcg agcgccaatc tgaataatat ctaaatagtc ataggcttcc tctagctgcc
    32101 tttcagacat aatctcacta acagccttca gcgaaaattc ctggcaaacc tcatgtagat
    32161 aggtaacccc tgtcagccct aagccctgaa aggagttaga agaggttcta ggcttatagg
    32221 ctccccctcg aaaatacctg tagcctaaag ccttggcact tgctgctgcc tgtctgattt
    32281 gctgataaga ttcaatggca cagggaccaa caataaagtt actcttttga cagcccttgt
    32341 ttaaaaaatc agctattata tcgtttccca tttatactct ttcctaatat gatattgaga
    32401 gaatgattcc ccaaaggtaa gatgacagct ctgtcttaga taatactgtg aataaggcat
    32461 gacagaacta ttcatagctt gggaaatcat accataatca agcttaaatt tcaagctaat
    32521 aaagagagtg accagctcgt tgacaaagga gaagcttttg agaatcctag ccctctaagg
    32581 tagagatttt atggctatta gagctgttga gaatgcttat tagctggaat aggcaagcat
    32641 ggtggggaag tgctgatgat tgagtatcat gatgaggcta gttatagctt ttattgtggg
    32701 agagtttagc ttttcaaata caaaaagaaa aggtttacct atatcgtttt tttggtgtat
    32761 atataatata tagaaagcaa actattttag aaacagaggt aatggtagat gttaaggtat
    32821 ttaaaagcga ttttatatct attggctccc agattagctt tttcagtaac aggtgtatta
    32881 tttcctgatg tttttgataa tttattcttg gtttataata ttttaatgac acttgctttt
    32941 tggcttgcga tttattctgt tgacctccca gaaaaatagt tgcgggactt gtttagtagt
    33001 tggttaacaa agggtagatg atcagttaaa ggtgaagcgt ctgagctatg ttggccatta
    33061 tgcgtacagc tggcaaaatg cttttgatcc aatcggttaa acctcaagct attctctttg
    33121 ggataacaaa taccccatct gtctcagaca aagaatggca acgcctaaat aggattaaca
    33181 tctgcaagtg ctcttgggac tgccaatgct cttagtagca taggtgattt ttcagcgcta
    33241 gagacttttc agcagatgag aaatagtcgc aataaacgaa gacaaaaaga cttggcttga
    33301 gctcgtattt ggccttaaaa tagtagtcag tcgagcttaa aaaaaagtca ttgcagctta
    33361 tgaaggttat cgtatcctta tttcaactga gctaggtaag ctagggagtt tcctttaggt
    33421 gtaacgatag aagcgatcaa ataattactt catttaaaga taaggattgt aataagcata
    33481 gaaaagagca gttacttgac ataactactc aatgtaaaac cgtttcaggc ggtggctttt
    33541 gttattagat aaaaaataat cgtcatcatt cggccaaagt tagaacggtt atgttttatg
    33601 ctcatctttg aagatgttat agcacaagcc aatagggaga ctaaagctta aaaagagttt
    33661 gagtagcttc aaaggctgct agctttttgg cctcctccat tttgttagct gttgatgaat
    33721 cgcccatagg caccaccacc cactcagaac gagcagccac ctgtcttaat ttttttactc
    33781 taccactgta gcatgccaca agaaaaaatc agaacactaa tgacatttta aaaaaaaaaa
    33841 aaaagacttg cacaccaaaa caagttatag tatcatagaa aggtagccgc tatagttaaa
    33901 tggtataata aagcaatggt aatgcttcgt tccgagttcg attctcggtg gtggcatctg
    33961 agtactgtcc taagtcttat taggacggtt tttttattgc taggtgaacc aatagtagtc
    34021 atctgtgaat cattaccata gtggcttctg ttcgcccaag catagcaaag ctgctgtcag
    34081 aatgaaccca gccaacaatg tcaatagaag cagcaccaga caagccttta gtcacccatg
    34141 ctttaaagat tttacggctg taatgttagt aactgttacc tgttttgttc aagttgtctg
    34201 tgacatcaaa tcacttgatg ctaccagtac tgtcaataca ttagctgtca cttggcagtt
    34261 gttctgacta ctactaaaaa tagcagctat cagcgttgca atcaaaaaag aatgcgaatc
    34321 aagctctcct gatcagctta actttttgaa agagtttgta cgggtcaagc atcagcaagt
    34381 cagactgcct tatttgtttt tatcataagc ttctaagaaa atagcacaat aagccaggct
    34441 gtggtataat ggtaaggatt aagtcagaaa gaggggggca gacatgtctt atgagcaaga
    34501 ctttttgaga gattttgaag actgggtgaa ggctcaaatt caggtcaacc agctagctat
    34561 ggcaacgagc cggcaaattg caaaggaaga taatgatcaa agagccagag atgcctttat
    34621 tcgttatgag agtaagctag atgcttatga gtttttatta ggaaaatttg ataattataa
    34681 taaaggtaaa gcttttcatg aggtgccaga cagcctattt ggtagccgtc attattagag
    34741 gaagggataa gcagtaatca tggcaagacg atacaatcgt aaaaaacaat acaagctaca
    34801 gcttaagcgt caaggactgc tcaaggcagt aatcaatcaa gtggagcaga ctgtggaaaa
    34861 ggtggttgat aagactaaag aagcagtgca taccgcttca caaatggtaa cagcatcaaa
    34921 gacagagact gctgatctac aggataagca gagcattgct gaaaaagcag ctcagcctaa
    34981 agcagatgta gcttctagta gcttggctga cagttctgag gtttcaagtg aaaaagaggc
    35041 ctcaaaggct agcagtgaag tcttatcacg cgatgctttt gcagagttgg ctgaggtttc
    35101 agagcttcgg gcagatattg ttacggtgct ttttgaggct ggtattaggt cagctgctgc
    35161 ttttagccaa tggacagagg cagagctttt ggcgcttaag ggaattggac cagcgactat
    35221 cagcaagcta aaggaaaatg gtgtcaactt taaaaagtag tctgattttt attgcttaat
    35281 aagtataaat ttgttagaat gttagcaatc agaggtatct tgagtttgtc tgttacagag
    35341 agcggtggtg ttgagaaatc cgcacagatg tcaagttatg tagctgaggc ttacaatgga
    35401 aaaatgataa agcagcagat taagtgtaat ctgaaacagt ggtggtaccg cggattatta
    35461 gtgaattcgt ccctgtctag tcgattgact aggcggggtt attttttgga ggacttgcta
    35521 tgattgagat aatgggttct gttgagaata atagattacc agatgtcaaa actagtcgtt
    35581 tgctgctgcg gcagcgtact ttagctgatg ttgaagcgat ttttgcttat gctagccgac
    35641 ctgaggttag ttacccagca ggctttccac ctgtgaaaac ccttgaagaa gaggagcatt
    35701 acatcgcaaa cacgatgcct aagcgctggc ttttgcaaca gctgccggca ggctatggca
    35761 ttgccctaaa gggtgacaat aggattattg ggtctgttga ttttaacaac cgtcacgcag
    35821 atgatgtctt tgaaatgggc tatctgctcc accctgatta ttggcatcag gggattatga
    35881 ctgaggcagc gagtgccctg ctagaggttg cctttactct gcttaagctt cataaggttg
    35941 aaatcagctg ttacgattac aatatgggga gtcgtcggat cgcagaaaag ctagacttca
    36001 ctcttgaggc gaccattcgt gatcgcaagg acgctaaagg caatcgctgc gcagacttgc
    36061 gctatggact gttgaaaaga gaatgggaga ggcagtgtag ataaggagta gactctctaa
    36121 aatatgcgtt aatctgtcaa aagcatttca taagaagtcc tcaaactcaa agcgcttatg
    36181 actaccaaaa ctggttagcg cttcgccaac cagtgtcatc agtttctggt agtctgcctt
    36241 gagcagcaag tgttatgtta agtgaggtga gaagaggtaa gagagatcgg aaagaggttt
    36301 ggtatgaata ttatcttaat tggagcacag gcgtctggta agatgacaat tggacaggaa
    36361 ttagaaaaac tgactgacct gactttattt cataatcatg aatcgattga ttttgtgact
    36421 aagtttatac caatgtcatc ggaagctaga gaactaattg atgagctacg attgctattt
    36481 tttaaaacat ttgcaaaacg tcagcaatca attattttta ctgttgtcat tgattttaat
    36541 gcacctgaag atatagcgtt tttggaaaca ctacagagtg tgtttcatga tttcgacaga
    36601 gaggttttat tcgttgaatt agaaatagat ttaaaagaac gcttaaggcg aaataaaact
    36661 gaaaatcgac tttaccacaa accgataaag cgtcatttgg agtggtctga gaaagatatt
    36721 ttggatactg ctaaatttgc taactttaac cctgcaaagg taccagaaaa tcttaaatat
    36781 tattgtaaaa tcaataatac gagtctttct gctcaagaaa cagcgcagtt tatcgtccaa
    36841 aaaatgaaag agttagaagt aagctagaaa ggacaccata tgtcaaaaga actttcaccc
    36901 aaatacaatc cagctgaggt tgaggctggg cgttatcaag cttggctgga ccaagatgtt
    36961 ttcaagccat caggcgacaa gaaggctaag ccgtatgcta tcgtgattcc accgccaaac
    37021 gttacaggga agctgcacct tggtcatgct tgggacacga cccttcaaga tattattatt
    37081 cgtcaaaagc gcatgcaggg ctttgatact ctctggttgc ctggtatgga tcatgcaggt
    37141 atcgccactc aggctaaggt cgaggagcgc ttgcgcgagc aggggatttc ccgttacgat
    37201 ctcggtcgtg acaagttctt agacaaggtt tgggaatgga aggacgagta tgcagcaacc
    37261 atcaaggagc agtggggtaa gcttgggctt tcactagact atgcgcgaga tcgcttcact
    37321 cttgatgagg ggctctcaaa ggctgttcgc aaggtttttg ttgagcttta caagaaaggc
    37381 tggatttacc gcggtgagtt catcatcaac tgggactcgg cagctaggac agctctttca
    37441 gatatcgagg ttatccataa ggacgttgag ggtgccttct accacatgaa ctatatgcta
    37501 gaagatggtt cgcgcgccct tcaagtagca accacacgtc ctgaaaccat gtttggagat
    37561 gtggctgtcg ctgtcaatcc agaagatcct cgttacaagg acttgattgg tcaacatgtt
    37621 gttctgccaa tcgtgaataa gctgatccca atcgttggag acgagcatgc ggatccggca
    37681 ttcggaacag gggttgttaa aatcacacca gcccatgacc cgaacgactt tgaggttggt
    37741 gggcgtcata atctcccaca ggttaatgtc atgaatgatg atggtaccat gaatgagctt
    37801 gcaggtgaat ttgcaggtat ggatcgattt gaagctcgta aggctgttgt ggctaagcta
    37861 gaagaaatcg gtgcccttgt tgagattgaa aagcgtgttc attcagtagg tcattcagag
    37921 cgtacaggtg ttgtggttga gcctcgcttg tcaacacagt ggttcgtgaa gatggaccaa
    37981 ttggctaaaa atgctattgc caaccaagac acagatgaca aggttgactt ctacccacca
    38041 cgcttcaacg ataccttctt gcaatggatg gaaaatgtcc acgactgggt aatctctcgt
    38101 cagctttggt ggggacatca gatccctgca tggtacaacg aagcaggtga catgtatgtt
    38161 ggtgaggaag cgccagcagg tgatggctgg aagcaggacg aggatgtcct tgacacctgg
    38221 ttcagctctg cgctttggcc attttcaact atgggctggc ctgatgtaga ctcagaagat
    38281 ttccaacgtt acttcccaac gtcaacattg gtaacaggtt acgacatcat cttcttctgg
    38341 gtgtctcgta tgattttcca atcgcttgaa tttactgggc gtaagccttt ctctaacgtt
    38401 cttattcatg gtctgattcg tgacgaagag ggacgcaaga tgtctaagtc gcttggaaat
    38461 ggcattgatc caatggacgt tatcgaaaaa tatggtgcag atagcctacg ctggttccta
    38521 tcaaatggct cagcccctgg tcaggacgtg cgcttctcct atgaaaaaat ggatgcgtcc
    38581 tggaatttca ttaacaagat ttggaacatt tcacgttaca ttctcatgaa taatgagggc
    38641 ttgacacttg agcaagcaag tgcaaatgtt gagcaagttg cgtctggcgc tgctggaaac
    38701 gtgacagact gttggatcct ccacaatctc aatgaaacaa tcggtaaggt cacagagaac
    38761 tttgataagt ttgagttcgg tgtggcaggt catatcctct acaattttat ctgggaagaa
    38821 tttgccaact ggtatgtgga gctgaccaag gaggttctgt acagcgacaa cgaagacgag
    38881 aaggttatca ctcgctctgt tctcctctac acgctggata aaatcctgcg tctccttcac
    38941 ccaatcatgc cgtttgtgac ggaagaaatc tttggtcaat acgctgaagg ttctatcgtg
    39001 acagcggact atccaacggt tgatcctgct tttgaaaatg aagctgcgca caaaggcgtg
    39061 gaaagtttga aggacttgat tcgtacggtg cgaaatgcgc gtgcggaggt taatgtagca
    39121 ccaagtaaac caatcactat ccttgtcaaa acaagcgata gcgacctgga agccttcttc
    39181 aacagcaatg tcaactacat caaacgcttc acaaatccag agaggcttaa gattgcttca
    39241 agcattgtga ctcctgagtt ggccatgtcg gctgttatta caggtgcaga aatcttcctt
    39301 cccctagctg atctgctcaa tgtcacagaa gaattagctc gccttgaaaa agaattagct
    39361 aagtggcaaa aagagcttga cctggtcagt aaaaagctca gcaatgaacg cttcgttgct
    39421 aatgccaagc cagaagtcgt tcaaaaagaa cgcgacaaac aggctgatta ccaagctaaa
    39481 tacgatgcaa ccgtagagcg catcaaggaa atggagaagt tagtaaggta ggatagtgat
    39541 catctaagag ccaattggct ctttttttga tatactgtca aggagtaatc atcacaatta
    39601 tctatataag tcaaaggagt gtctcatgaa aaaaagagtc attggttggt taggtgtgct
    39661 ggtaataggg cttatgcttg gtctgatatg gtggaaatgg ttagtggcag atcggccact
    39721 aacccaagca ggtcaaggaa gtcatgacca cagcagcgac aaaggcctca gtgccgcata
    39781 aggaaaaaat ggaatcaaaa gagcctgaga catcacatca gccagaagcc tatcctgatc
    39841 ttgctagcta tcaggaattg gctgttcatg tgtcgattgc agaccaagtc atgaccatta
    39901 taggagatgg taaggttatt tttaagacca gcgtgtcaac aggagcaaag gaaagtccaa
    39961 caccgacagg gacctttgtc attgagcctg agcgaggaga ctttttcttc aatcaggcat
    40021 cagaagaggg agcttattat tgggtgtcct ttaaggacca tgggatttat ctgtttcaca
    40081 gcctaccaac agaccaatat ggcaatgaga ttccagagga ggcagagaga ctgggacagc
    40141 cagcctcaca tggctgtgtc cgcatgagca gagcagacgc caaatggttt tatgacaata
    40201 tcccagaagg catcagcgtc acaatagaat agccctaatc tccctcagaa tagcctgagc
    40261 agatagagga agagcctgtt aatattagca ggcttttaaa gctccttaaa aggctgcaaa
    40321 aaggaacgaa aaaagacctg aaacaggtcc attgatctaa gagaagacaa gtaactagcc
    40381 ttctagcaaa gtgttttaaa aatgcgttag tttagtagct tcgtgataat acaattaata
    40441 atatttattt aaaaaaactg taaatttcga ccactgttcc tggatttttt catttaaacg
    40501 tttatgccat gacttatgag cattctctct aatttctttt aggtatatat tttctactac
    40561 ccttttttga ctatgttctc gctctttttt tatttgctgt cttaaattct cttgtttttt
    40621 ctgttcttct aactcttttt gagctttctt ctgttcttgc tctattatgt cttgaggttt
    40681 agattctcct acaatccata tttctgaacc taagacaaaa ccatctgagg taatatgaac
    40741 tctaaattta tcaccattag aagcaatttt attatatgga acatatgttt cttctttgga
    40801 atttgttttt tgtgttctcg ctgattctaa agagaacaca atttttccat cccactttgc
    40861 aattggatag taccggttat ttgttaagtc accattgctt tttttttgga cttgtactaa
    40921 ttcagtttcc ttatcatctt cttcgacttt aaatattcta atcaaagatc ctggactagt
    40981 ttttactact atttctttgt cattattttt gattggttta acgccaaagt ctcgagcgtt
    41041 ttcccaatct cttctaaatc ctattacctt ttggtcacca atttgtggtg cttctgtata
    41101 atcatcataa ccataatagc cttgccctaa aactggagaa ttttcataat cactatttgc
    41161 acttacttcg ttgaaacata ttaaacttag taaaggtaaa ttaacgatta aactcatcac
    41221 taacttcttc ttcatttttt cttcctaacc tccattactt atgtttattt aataatagct
    41281 agggttagta taaatgagat gttgtgtaag gtaaagatgt ttattaaaag tgactaaaag
    41341 taaagaaata atcctaatag tagtttgggg atattttgat ttatacaaaa aataatgtca
    41401 ttgaacacgc tttatctaaa atagtctaac attctaacga aaataattcc aattattttc
    41461 atatactggc tagacatgct gtattagctt aatcaagaat tacagccgca gttttaaaga
    41521 cactcaggtt agtgtattat aaaaagctgg tgtgggttac aaaggatttc atatcactta
    41581 gattatgtca taattagtta agatgatgaa tccttatcta aaaacaaagc aaacttgtac
    41641 gtttgcgact ttcgtgatct ttaagcttac aaaagctgag taaattggta taatgatcat
    41701 taaaagagct catgctatga tgtagaccta taaaaggaga aaaccatgac atttgaagag
    41761 attttgccag gcttgaaggc caagaaaaaa tacgttcgta agggctgggg aggcgctgaa
    41821 aactatgttc agctgtttga tagcattgaa caaaatggtg tggcacttga ggtgacgcct
    41881 tactttttga ttaacgtgtc aggagctggc gagggctttt ccatgtgggc accgactccc
    41941 tgcgacgttc ttgctactga ctgggtagag gtctatgact aagcgggtgc tgatcactgg
    42001 tgtgtcatcg ggcataggac tggcacaggc gcgcctgttt ttgagaaatg gctttactgt
    42061 ttatggggtt gacaaggcaa aaaagcctga tttatcagga gattttcagt ttttacagtt
    42121 agatattaca ggtgatttag ctgagctttt tgaggctgtg cctagggttg atgtgttgtg
    42181 tcatactgcg ggcgttcttg atgcctataa gcccttgctt gataccacac aggctgattt
    42241 tgaggctctc tttcaggtca atttctttgc agctgtccgc atcacgcgtc actatttggc
    42301 acagatgctg acagctcaat caggtattat catcaatatg tgctctattg ctagcttcat
    42361 ggcaggtggc ggcggagctg cctatacctc cagcaagcat gctctggctg gttttaccag
    42421 acagctagcg cttgattatg ccaaggcagg cattcaggtt tttggcattg cccctggcgc
    42481 agtgcaaaca gcaatgacag ccacagactt tgagccaggt ggcttagccc agtgggtggc
    42541 tgatgagact cctatcggtc gttggcttag ggctgaagaa atagccgagc tgaccatgtt
    42601 tttggcatct ggaaaagcta gcgccatgca gggagaaatt gttaaaattg atggcggttg
    42661 gagcttaaag tgaaacagca catcgacata aggcctagca agatctggct tgtctgtaca
    42721 gagggtgaca gttgatagct gtatcaagca atcttgtcac aggctaagag ggagctgatg
    42781 aagttttttc catgaagcct agtgcctagt aggtttgctt aatacagcag gagcctacct
    42841 gtctagagga ttcgatcaat agaggtgata acatgactgc agaagaatta tggtctcaat
    42901 accagcaaat caatcctggt gttggtgatc tagctgaggc ctgggccttt ggagctgagc
    42961 ctgatttatt agcgcaatta gtgctagaag gcactaaaac agctacagcc tctgcctatg
    43021 actgatatga gcctgatcat gagccgcttt ccaaagaggg cagctatgac gtgattttgg
    43081 atagtaggga tcaggcgatc tgtattatcc agattactaa ggttagtctt gttcccttca
    43141 aggacgtgcc agcagagcat gcctataagg aaggagaggg tgataaaagc ttggaagaat
    43201 ggcggctgct tcatgaggcc tttttcagac cttattttga agaggtaggc ttacgcttta
    43261 ccgaggatag ccttattgtg ttagaggagt ttcagagggt ttaccctgaa gctgctaaaa
    43321 aggagaaata aatgaaatta gcccttgttg gtacaggcat gattgtcaaa gaggttttgc
    43381 ctgttttaaa ggagatcaaa agcatagact taatggcgat tgtttcaacg cctcgtagtc
    43441 ttgaaaccgc agaggcgctt gctgacgcct ttggcattca acaggccagc tgtcagctag
    43501 ccgaggtcct aaaaaatgaa gaggtggata cggtttatgt tgccacccca aatcatttgc
    43561 attttgaagt ggctaagcaa gcccttgagg ctggtaagca tgtcatttgt gaaaagccat
    43621 ttaccatgac agccaaggag cttgatgctt taagcagcat tgcaagagct aagcagctga
    43681 tattattaga agctattacc aaccaatatt tgccaaacac ccaatttatt aaggatcact
    43741 tgactgagtt aggagagatt aagcttgtgg agtgcaatta ttctcaatat tcctctcgtt
    43801 atgatgcctt taagcgtggg gagattgcac cagcctttga tcctaaaaag ggtggagggg
    43861 ccttgcgtga tttgaatatt tataatatcc atctgctcgt tggcttattt ggcaagcccc
    43921 aaacggttca gtacctagct aatatggagc ggcaggttga cacctctggt gttttgctga
    43981 tggattatga gcgatttaag gctgtttgta ttggggctaa ggattgcagt gcagagattg
    44041 tctctacgat tcaggggaat aaaggctttc tttctgtttt aggtgctcct aatgctgtac
    44101 cagagctttt actagccatt cgaggtgagc aagcaaggac cgtcaacttt aaccacccgt
    44161 ctcatcgcat gtacgatgaa tttattgcct tttcagatat tatctctaat aaggacatgg
    44221 aaagggcaga gcaggccttg gagcacagca aggcagtcat ggctgtttta gagcaggcag
    44281 cagcttcgct agaaagcgat agctaagagt agctagtggc tacaagctaa gtcatctttt
    44341 ttgctagctg tcttaagaag tgatgaccct tcttgttcta tcagatacag gtcttgttcc
    44401 tgatgactcg gagtctttca atcgcggagc ctaactgctt ttttcatagt gaggggtcta
    44461 atttgcagct tgctttgttt acgacatctt tgatacttag cgatgacagg cagctctagc
    44521 tagctgcttt aaaaaaggag tcaaggtagg taagggagtt tgtctgaagc taaggactat
    44581 tgcagcattc ttgttttttc tgcaaattaa ggccatttgt gctataatga gatgatctat
    44641 gtacaaacgg aggaagtcat tatgccaaac tacgccatta tcctagcagc tggaaaggga
    44701 acccgcatga aatcagggct tcccaaggtg ctgcacaagg tatcaggctt aagcatgctg
    44761 gagcatgtcc tcaatagcgt ctcagcccta gctcctcaaa agcaactcac agtgatcggt
    44821 catcaggcag agcaggtacg tgccgtccta ggtgatcaat cactgacagt ggtgcaagag
    44881 gagcagctag gaacaggcca tgcagtcatg atggcagaag aggagctatc tggcttagag
    44941 ggacaaaccc tagtgattgc aggtgacacc cccttgatca gaggagaaag tctcaaggct
    45001 ctgctagact atcatatcag agaaaagaat gtggcaacca ttctcacagc caatgccaag
    45061 gatccctttg gctatggacg aatcattcgc aatgtagcag gagaggtggt caatatcgtt
    45121 gagcaaaagg acgctaatga ggcagagcaa gaggtcaagg agatcaacac agggacttat
    45181 atctttgaca ataagcgcct ctttgaggct ctaaagcatc tcacgactga taatgcccaa
    45241 ggggagtact acctaaccga tgtgatcagt attttcaagg ctggccaaga aagggttggc
    45301 gcttacctgc tgaaggattt tgatgagagc ctaggggtta atgatcgcct agccctagc
//
LOCUS       DARYXZ010000014        43743 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYXZ010000014 DARYXZ010000000
VERSION     DARYXZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43743
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(19..1290)
                     /locus_tag="TV186_000665"
     CDS             complement(19..1290)
                     /locus_tag="TV186_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL1532081.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
     gene            complement(1283..1891)
                     /locus_tag="TV186_000666"
     CDS             complement(1283..1891)
                     /locus_tag="TV186_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL1532082.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TV186_000667"
     CDS             complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TV186_000667"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL1532083.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            3817..4287
                     /locus_tag="TV186_000668"
     CDS             3817..4287
                     /locus_tag="TV186_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL1532084.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4289..4633
                     /locus_tag="TV186_000669"
     CDS             4289..4633
                     /locus_tag="TV186_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1532085.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            4650..5078
                     /locus_tag="TV186_000670"
     CDS             4650..5078
                     /locus_tag="TV186_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1532086.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(5276..7813)
                     /locus_tag="TV186_000671"
     CDS             complement(5276..7813)
                     /locus_tag="TV186_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1532087.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            8376..9329
                     /locus_tag="TV186_000672"
     CDS             8376..9329
                     /locus_tag="TV186_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL1532088.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            9329..10075
                     /locus_tag="TV186_000673"
     CDS             9329..10075
                     /locus_tag="TV186_000673"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL1532089.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            10324..11328
                     /locus_tag="TV186_000674"
     CDS             10324..11328
                     /locus_tag="TV186_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1532090.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            11625..13811
                     /locus_tag="TV186_000675"
     CDS             11625..13811
                     /locus_tag="TV186_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1532091.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            13889..14710
                     /locus_tag="TV186_000676"
     CDS             13889..14710
                     /locus_tag="TV186_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1532092.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVPLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TV186_000677"
     CDS             complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TV186_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1532093.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFPVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TV186_000678"
     CDS             complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TV186_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL1532094.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            17294..18898
                     /locus_tag="TV186_000679"
     CDS             17294..18898
                     /locus_tag="TV186_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1532095.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLNDIAISRDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGKDDY
                     YNLLMHLSSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDSYAKLLEAKLAVIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            19121..21340
                     /locus_tag="TV186_000680"
     CDS             19121..21340
                     /locus_tag="TV186_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL1532096.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            21355..21798
                     /locus_tag="TV186_000681"
     CDS             21355..21798
                     /locus_tag="TV186_000681"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL1532097.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(21925..23217)
                     /locus_tag="TV186_000682"
     CDS             complement(21925..23217)
                     /locus_tag="TV186_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1532098.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            23972..24820
                     /locus_tag="TV186_000683"
     CDS             23972..24820
                     /locus_tag="TV186_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL1532099.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            24970..26103
                     /gene="ugpC"
                     /locus_tag="TV186_000684"
     CDS             24970..26103
                     /gene="ugpC"
                     /locus_tag="TV186_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL1532100.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            26287..27906
                     /locus_tag="TV186_000685"
     CDS             26287..27906
                     /locus_tag="TV186_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL1532101.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            28015..28377
                     /gene="traF"
                     /locus_tag="TV186_000686"
                     /pseudo
     CDS             28015..28377
                     /gene="traF"
                     /locus_tag="TV186_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            28491..28850
                     /gene="yajC"
                     /locus_tag="TV186_000687"
     CDS             28491..28850
                     /gene="yajC"
                     /locus_tag="TV186_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL1532102.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            29024..29773
                     /locus_tag="TV186_000688"
     CDS             29024..29773
                     /locus_tag="TV186_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL1532103.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            29783..30577
                     /locus_tag="TV186_000689"
     CDS             29783..30577
                     /locus_tag="TV186_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL1532104.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            30609..31874
                     /gene="rseP"
                     /locus_tag="TV186_000690"
     CDS             30609..31874
                     /gene="rseP"
                     /locus_tag="TV186_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL1532105.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            32144..34000
                     /locus_tag="TV186_000691"
     CDS             32144..34000
                     /locus_tag="TV186_000691"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL1532106.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            34052..34609
                     /locus_tag="TV186_000692"
     CDS             34052..34609
                     /locus_tag="TV186_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL1532107.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            34944..39341
                     /locus_tag="TV186_000693"
     CDS             34944..39341
                     /locus_tag="TV186_000693"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL1532108.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            39463..39891
                     /locus_tag="TV186_000694"
     CDS             39463..39891
                     /locus_tag="TV186_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1532109.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            40021..40566
                     /locus_tag="TV186_000695"
     CDS             40021..40566
                     /locus_tag="TV186_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1532110.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(40745..41359)
                     /locus_tag="TV186_000696"
     CDS             complement(40745..41359)
                     /locus_tag="TV186_000696"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1532111.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
     gene            41724..43151
                     /locus_tag="TV186_000697"
     CDS             41724..43151
                     /locus_tag="TV186_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1532112.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            43417..43686
                     /gene="rpsO"
                     /locus_tag="TV186_000698"
     CDS             43417..43686
                     /gene="rpsO"
                     /locus_tag="TV186_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL1532113.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT        12328 a         8697 c        10414 g        12304 t
ORIGIN      
        1 cttgtttttt tctttaggct agctgctaga aagcttatca attcgcgctt tattggcggc
       61 taaggctctt tcatattttc ctgtttcatt tgggttgaag taatttttct taaccaagtg
      121 atcagggaga tattgctgct tgacccattt ttctggatat gcatgagggt aaaggtagtg
      181 ctgagcattg cctagctcct tgctgccggc ataatgccca tcacgcaggt gtctaggaat
      241 gggaagatgg ccatgttgac gtaaatcagc gagagcagcg tccatagcca tataggcgga
      301 attggacttt ggtgacagtg ctagatcaat cacaacattg gcaatgagga tacgcgcctc
      361 tgggaagcca attttctggg cggcctcaag tgcagtgacg gtatggattt gagcttctgg
      421 attggcaaga cctatgtcct cataggcgat aatggtcaag cgtctagcaa gactcggaag
      481 atcgcctgcc tcaataagcc ttgcagcata gtgcaagcta gcattaacat cagatcctcg
      541 gattgatttt tgcaaggcag atagtatgtc ataatgtccg tcgccatctt tgtccattgt
      601 gatgtagctg cgctgcaaag aattttcaac agtattcaag ctgatatgac ggataccctc
      661 ggtatctggc tgggttgaca tgacagctag atcaagggat tggtaggcgg ctcggagatc
      721 tccatttgtc gctgtcgcaa taaagtcaaa agcagcctca tctagggtca catcaaaggc
      781 aaagcctctc tccttatcag tgatggcaag cttaagcgcc tgcttgatct cctcaggtga
      841 taggggctcc agctcaaaaa tctggactcg acttctgatg gctggagtaa ccgagaaaaa
      901 aggattccct gtggtagcac caatcataat aatgtgccca tgctctaaaa gtggtagtaa
      961 aaagtcctgc ttactcttat ccaatcggtg aatttcatca agcaaaagca caagtccacc
     1021 tgaaaactta gcttcctcag cgatttcttg gaggcgtttt ttattgtcta tggtagcatt
     1081 gaaggttcta aaggcgtact tggttgttcc agcaatagca ctagcaattg atgtctttcc
     1141 aataccggga ggtccgtaaa gaatcattga ggctaatcta ttggccttga ccatgcggtc
     1201 aatgattttt ccctccccga ccagatgctg ctggccgatg acctctgtaa tggttctagg
     1261 gcgcattctg atggctagat tatcaggcat tgtattcctc ccttccttgc ttttgttggc
     1321 tgtggtgctt tttaacaaca gccataaagt ttgcgatcat tgtcctaccg tcagctgttc
     1381 cgatgctttc tgggtgaaat tgaaggccaa acagtggcag ctgtctgtgt tcaaaggcca
     1441 taatctcatt gtcctcaaag tctcttgcgg taattacaaa gtcagctggc aggtcatcaa
     1501 caacaataga atggtaacgc atgacggtta attgctttgg cagctgttga aagagcttag
     1561 ctggtgcttg tctttcaagt atactttgct tgccatgcat gacgcgctta gcaaggcgta
     1621 gcctgccacc tagagcctca gcgatagctt ggtggccaag gcaaacgcca agcataggct
     1681 tttggtcata aaaggcccta atcaagctag gcatctgatt ggcggctttg ggccagccgg
     1741 gtccaggtga gaggactatg gcgtcagcct gcttcgcaag gtcaaatagt tttggatcct
     1801 gattggtcaa tacaatcgtt tgatcaaagg cactgaggta ttgggccaga ttataggtaa
     1861 atgaatcgta gttatcaatt aaaagtatca taaggtcctt catctagtag tgctgaggga
     1921 tcagcctggt actattgagg cagagtggtg tcctcaattg ttagtgagta gagtcctcgg
     1981 acagcattgc caccaaaaat ggcttcggcc ttgtctaaat ctgaaagctt tagctctttt
     2041 tcctgagcca gtccctgcct tagtaattct tgacggaaaa tgcctggtag aataccggct
     2101 gatacaggcg gtgtataaag ggtctgctcg atttgcacaa aaagattacc aatagaggtt
     2161 tcaagcaagg tcccatcagc agcaacaaag acttgctcat aaggcttgac gctcagatgt
     2221 ggtcgatgac tggttttaaa ataagtaaag ggaagctttt tgacatcgct tgattggcga
     2281 actaatcgtg cctttaaaaa gtctttttga agcggctcta agctttggtc tgtaaggcta
     2341 atctgcccgt ccttagcaat agcaatagtg agacgatagg ggctgctgtc ctttcccttg
     2401 agataggctt gcaaacgatc tgtcagaagc tcttcgtcat aggggtaggc aaaataacgc
     2461 gccgcctccc ttagtctgtt gaggtgctgg tctagatata ttaggctttg ttgttcgacc
     2521 ttggcagtgg ttttgatggt gaaatcaatg ctttgacggt tcagaaagga agatttttgc
     2581 ttgatttctt caaattcgtc ctgccagcag ctttcccagg taatcccacc gcctaccccg
     2641 tagatggcct gatcgtagct gagctgaatc gttcgaatag cgacattgaa gacacgtctg
     2701 ccatcaggca ggcaaatacc aatgctgcca cagtaaacgc cccttggctt aggctctaat
     2761 cggttaataa tagccattgt agacacctta ggagctcctg tgatggagcc acagggaaag
     2821 agtgcctgta aaatatcata aagacgacac tgatcctgca gcatgccgac aatggtagag
     2881 gtcatctgcc aaacggtgga atattgctcc aattggcaga gctgtgtgac tgtgacactc
     2941 ccagtttgac agatcttatt catatcattg cgtaataaat caacgatcat catgttttct
     3001 gaacggttct taggatcggc ctgtagccag tcatgctctt gttgatctag ttctaaattg
     3061 taaccacgct tggttgtgcc tttcatgggg cgtgtggtga tctggttttt ctcttgcttg
     3121 aaaaataact caggactggc tgaaatgaca gcaaagtcat cgtgagcaat gtaggcattg
     3181 tatccagctg cctgttcaat gaccaattga tgataaatgg ccaagctgtc cttagcgttt
     3241 agcctttggc tgagctgaat ggtatagttg acctgatagg tattgccctg cctcatctcc
     3301 tgatgaatct gtgcaatagc ctcttgatag gcttcctctt gtgtagcact tgtccagctg
     3361 tttggaatcg tcatgctgtc gtggtagagc ggaaagtcct cgagctgaca gctgtcatgc
     3421 actgtaaaat aagcaaaata ttcctgacca agtcttttat tgtgtgttgt tagctttttg
     3481 tcaaaacagg ctgctgcttc atagctgagg tagcccacaa catagtagcc cagatcttga
     3541 aattggttga cctgctcaag gacctgtccc acctgatcaa tctgcttagc tactaattcc
     3601 acgataggag cttgaaatat atagcgttgt cccagctcct taaaatcaat aatcgtcttt
     3661 atatgcatag cttgattata tcataaatgc gcttttcaga ctgattagga gggttgaaaa
     3721 gaagcctgtt agcaaccatc aacaatacaa gagagcaggg cttcttgatt tatgctacaa
     3781 tagtagcgga tattatttag aaaaaggaac aagagcatgg ctaaatatgg ctttttatca
     3841 gtattagaag aagagatgga caagcatttt cattatgact atgctatgga ttgggacaag
     3901 aaaaatcatg cggttgaaat cacccttgtt ttagaggctc aaaatcagtc agcagttgaa
     3961 accattgatg accaaggaca gctcagcaag gaagacattg tctttgagga ttatgtctta
     4021 ttttacaatc cggagaaatc acagtttcaa gcagcagact atctggtggc tattccattt
     4081 gagccaaaaa agggcttttc tcgtgaattt ttagcctatt ttgcccagtt tctcaatgat
     4141 gttgccattg aagggcatag cgatttgatg gatttcttag cagatgatag caagcttgat
     4201 tttagtctag agtggaacga ggaggccttt gaggaagggc aggtaggact agaggaaaca
     4261 gagctttata gctatccgag gtattaagat gctacatgag atgatgctga caccaagacc
     4321 atttgctatg attgaggcgg gtgtgaagac tattgaacta cggttaaatg atgagaaaag
     4381 gcaggctatt aaggtagggg attggatttg cttttattgt acagaggatc atagccatat
     4441 tctgcaagca gaggtcgtag ggttgcatta ttttgatgac tttgctaagc tttaccaagc
     4501 attgccttta gaaaaatgtg gttatcgtaa tgaagaattg gcactggctc ggccggagga
     4561 tatggaacag tactacagca aagagcagca agcccaatat ggcgttgttg gtattgagct
     4621 aaggctatgt tgattggtga gatctagtca tgaagctttt agataaaaca gtccattttt
     4681 ctggtgcaaa gttagccttg atcagtaacg gtaagatttt gaccatcttg cgtgacgcga
     4741 taccaacgat tccttaccct aatatgtggg atttaccagg aggtggtcgt gaaaatgctg
     4801 aagctccctt tgattgtgcg tcacgtgagt gctatgagga gttaggtctg gcactgacta
     4861 aggacgctgt cgtttgggaa agggtttatc cagggcttgt taatcctgac agccaatctg
     4921 tctttctggt ggctcttatg aatcaggaca tgatagatca tattgctttt ggtgatgagg
     4981 ggcagggtta tcagctgatg gctattgatg actttttagc agacgatcgg gtcattcctc
     5041 agctaaaggc tcgcttagct gattatttaa ggaaataggc agacttagct ggtacactaa
     5101 acagatcagc aaacaccact actatgtgat agctacgacc agaatcaaaa agacgattga
     5161 cctctgccca catgtggcta ggatcaatcg tctttgtttt tggggtggct aagtctttaa
     5221 tctggtaggc cagatcagct gagtagttga tattatcaat cagtcctgct atggcttagc
     5281 tgttgctagc tactgatgtg ctgctagctg tctctgactc acctaaaaaa tagctggctg
     5341 gcttatcact tactggcgtc ttaccaacaa gctcagggtc aggtgctaat aggtcgtcct
     5401 cgtcggagtc agaaacgggc gctacaaatt cttctagcca gcttccagtg ctgccagtgt
     5461 gattaggagt ttgaggctcc ttaggtagtg gatcacctgg tagccaggta ttccctgagt
     5521 gattactatt acctgtaaca tcgttgttgg ttattttatc aaagttgacg ttataaacaa
     5581 tatcctcagt gacttcctta tcatattcct cagttgaaat aataggctta ttgtaatcac
     5641 gcttgtagcc ggcatctggc tgtactgatg gtggtaggat accagctgta tgtaatgagt
     5701 gtcccttacg aacaaggtaa acggcagtct tacccttacc agctcggcta atcagctgtc
     5761 cgccctctcc tgccttaaag gcaacggcta catagtgtct cggatcgtgg aagtaataat
     5821 tagggtgtct gctaggatcc tctagatcag ttggcttgtc aggattaaca gcgatgtaag
     5881 gtccaatata aggagcagta gttccaaagg ctgctgagaa taggccagta aaggctacct
     5941 tatcgttttc attttgtgtg atagaaaatc tcttagcaaa atcagttaga ttaaagttat
     6001 tggcaaggtt cactccactg cggtattcaa taaattcata gcctggatct gggacgggct
     6061 cagggataac aagtccttgc tccttagctt ccttccaggt aagaccacta cgaacattgt
     6121 agaagaagcc tccttgagtc acgccgttaa gcttcaatcg cccattaaag attgtggtga
     6181 accagacagg aacataattt tctaagtcaa ggtctgaaac atcatcacct ggcccgtaga
     6241 cagccttggt aggctgcttt ctaaccttat caaaatctac atagaagcgt tgatgttctc
     6301 tgtccatctt gccagctgtt ggcaactcag cactccagcc cttaaagata cgcccctcat
     6361 gcttgattgc ctctggacgc tgaatgttca aatccttcca gtccaaatcc ttacgaacca
     6421 aatagtgcac acgtttagtt ttaatgccat taacctcaat gtcgccgtat tcactatttg
     6481 tactaaacaa cacatggata aagtttttga tgtttttgat gccctctggg tgatattttt
     6541 tatagacccc atcacgtgtt agattttcag atgaattttc cgtatagaaa ggaccataaa
     6601 cgagctgagt ttcgacctct agattggttg attctgtctt gacattgcgc tcaggatcat
     6661 ctggcaattc tgggtcaatc ttatagatgt gagcatggtc cccatgacta atggtcatgt
     6721 agttgccctc aattgagatg tcctcacgac gaaccttgaa gcgatccata aattctttga
     6781 tgagtctttc tttgcgctgt tcaaaggttt ctccgtctat ctttttgagg atctgttctt
     6841 ctggagtttt aaatggctta gaaagatcaa tatcctttag ccagatgacg tgcgtgtggt
     6901 cctcatgagg gtattcaaag ccgacctgac cgtctacatt cacctgctta atgcgtgctt
     6961 gatctacctt tagctccttg gcgagataag ctatataggc gcgatagtct ccttcctgag
     7021 gcttggtgtg gtcctttttc ttatattgct ccactaaata agcccatttg ctacgcttta
     7081 agtcctcaaa gctaataggg tgcaaatggt tcccatgctt caccaggatt ccagtgtcag
     7141 tgacaccgct aatgttggtg ccatcaaata agaagccatc actagttttg aagtcaattc
     7201 ctgggatacc cccctgctga tgaatgctag gtggtgttga tgggaagtga ggtgtggttg
     7261 atgcgatgtg gttgatggtt gctgatggca ggcttgattt gaggatatag tggtaatgat
     7321 ctccatgacg aacagtgtag ccataggcgt cctcagcaac aatgtcagct ggattaaaga
     7381 catagccgtc tccagcatga ccagttgaga ctactgatcc agaccttgcc gcttggttag
     7441 aagcaggctg tgcttccttg taatccttag gaatcaggta agcccatttt gtccccttca
     7501 aatctgagta aaagaagaaa tgcttgtgat cgccatgctt cacaatgata cctgtatctg
     7561 ttttgcgttc aatttgcgat tcgctggtca ataaaaagcc atcatcagtt gggacatcaa
     7621 tcccagggac ttggtgacgt tctctttttt tcgcagtctt actgcttttt tgttttttct
     7681 ttttcgtagc cttttggtgc tttttaggct cctgagaatg tcccttttgc gaatgcgttt
     7741 ggcaggctgt taaggcaagg ttgcaggcta acagcagtcc aacgagggat aaaaatcgtt
     7801 gatgttgttt catggttagt tatcaactcc ttccaacaat taacttaacc agttaatatt
     7861 attactggtt aagtatatca tttgacatct aagaatacaa tagattttat aaatttttta
     7921 atgaaattaa tctaatgacc taagagctgt ctggaagatg aaaggctttt tagctatttc
     7981 aaaggcttgg agcttcaaca ggcgaatcag ctattggttt ttctggattt acgagaaaga
     8041 gctgctcttt tttgatgtag ctggtataaa atatggtaaa atagggtcta tcaagagcct
     8101 atctaccttt agattggctg agatttgtta ggcaatgcgt ccctgataaa ggttgggctt
     8161 atgggacaat aggccttggt gctgtgtttg tccttagtat gaaacctctg agacggcaga
     8221 gcaggatccg gttggtttag gaccgcatta gcttatctta cgataaaaaa gaagcttgaa
     8281 aggaaaggct gctttgatct gatagagggt cactggtttt agggtttagg ctaggggcaa
     8341 gtgaccactg atgatatggc agcaagggta tcgttatgaa ggcatggcaa gagctgacaa
     8401 ttacagtcca tcgtgaggca gaagaagctg tttccaatct gctgattgag gctggcagcc
     8461 aaggagtcgc tatcaatgac actgcagact atatcggtca agaggaccgt tttggggagc
     8521 tttatccagc tgttgagcag tcagaaatgg ttactattac agcctattat ccaagctcag
     8581 ctgatattga tgacatcaga cagaccatta atcagggctt gaacaggcta aagcagtgtg
     8641 atgtggagct tggtgagtta accctgacca atcaagaatt ggctgaagag gattgggcgg
     8701 acaactggaa agcctattat gagcctgctc gtatcacgca tgatttgacg atagtcccca
     8761 gttggacaga ttatgaagcc acagcaggtg agaagatcat taggcttgat ccgggtatgg
     8821 catttggaac aggcacacac ccaacaacta agctaagcct gtttgccttg gagcaggtgc
     8881 ttcgtggtgg tgagacagtt attgatgtgg ggacaggctc aggtgtgcta tcgattgcta
     8941 gctctctgct tggcgccaaa gaggtctttg cttatgattt agatgatgtg gcggtgcgtg
     9001 ttgccaaaga caacattgcc ctcaatcaag ccactgacaa tatccatgta gcagctggag
     9061 acctgctaaa aggccttact caagaggcag acgttattgt cgccaatatc ttggcggata
     9121 ttttggtgca tgtgacagca gatgcttacc gtcttatcaa gtctgagggg tatctgatca
     9181 tgtcagggat tatttcagaa aagctggata tggtgaagca ggctgctctt aatgcaggct
     9241 tcttgctaga gactcacatg cttcagggcg agtggaatgc tcttattttc aaaaaaacag
     9301 atgatttatc aggagtgatt ggtggctgat gcagcagtat tttattaaag gcagggcaga
     9361 aaaaatcgtt cagctgaccg ataaggatac cattaagcat atgtttcaag tgatgcgctt
     9421 gacggataag gaagagctgg tgctagtctt tgatgacggc attaaacgct tggcaagggt
     9481 gtcagacagc tcagcctatg aggtggagct tatcaaagag ctggaagaaa accttgaaat
     9541 gcctgttgag gtgactattg cctcaggctt tcccaagggt gataagctag atgttatcac
     9601 tcaaaaggcg actgagttag gggcagcagc tatttggggc tttccagcag actggtcggt
     9661 ggtcaagtgg gatagcaaga agctagctaa aaagcaagaa aaattagcta aaattgctct
     9721 tggagcagca gagcaatcca agcgtaatcg cgtaccggag attcaactat ttgaccaaaa
     9781 gggtgagcta ttaaagcagc ttaagcagtt tgataagtgc tttatcgctt atgaggaagc
     9841 agctaaggca ggtgaaaggt cgacattggc gcgtgagcta gcaggtctta gcccaggtca
     9901 aaaagtcctc tttatctttg gaccagaggg tggtatttct tcaaaagagc tggctagctt
     9961 taagcaagca ggtgctatta ctgtgggact ggggcctcgt atcatgcgga cagaaacagc
    10021 accgctctat gccttgagtg ctgttagcta tgctctggag ctaatgtcta gctgatagtg
    10081 ctaataggag acagcacctt gtggctcagt gcttgacaga aaaaagagga gcatctgcga
    10141 ttatgctaat aaagcaccgc ttaacaaaaa gatcgctaag aaggagactg ccgcaaatca
    10201 aagggctagt ctagcccgcg taggtgcaga gctgtcgggc ctttgcagct tcatttgtaa
    10261 aaaatataac aaatcatctc aaaataaaga tactcgtcaa acggattggt agaggaggga
    10321 catgtggtta cgataaaaga tgtggcaagg ctagcaggag tttcgccttc aacagcttcg
    10381 cgtgccatca atgacagtga catgattagt caggcgacaa aggagcgtgt caaaaaagcc
    10441 atggaggcct tggattattc gcctaattat tcggcgcaaa accttgttaa gcgaaagtcc
    10501 aatactgtcg ggatcatttt gccggtgcgt gagggtcagg attcactggg aaataaccct
    10561 tttttcatgc agattattca aggaattgct gctgtttgta ccgatcaggg ctacatggta
    10621 gcccttgcga ctggacgtag tgaggccgaa ttgctaaaaa acgtgcaaaa catgatccgt
    10681 agtggcaata ttggcaagct gatttttctt tattccaaaa cagatgatca ggtttttgac
    10741 tttgtcaaaa ggcaaagagt ggattgtgtt gtcgttgggc aatcaacgac aaaggatcct
    10801 ggcaatgcta aatttgtcaa caacaataac catcaagccg gctatgatgc agcagcattt
    10861 ctccttcaaa aaggctatga ggctattgtc tatgcttata ctgacatggc cgaattggtg
    10921 caggcagagc gttataaggg ctatgcagag ctgatgactt caaaggctct ggcagctcaa
    10981 gccctttgtg tcacgctaaa ggacgatagg aaaagtcaaa agcagctgtt agaccaatta
    11041 gccaagcgct ctaaagttgc ctttgtagtc tgtgatgatg tgctagctat tcatttgcag
    11101 cgtctcatca agcaagtagc agctgacacc cagctagcaa tcgttagctt caataattct
    11161 gtcctagcgg agcttgcgag tcctgccttg acctccattg ctatttttcc ctatcagctg
    11221 ggagagcaag ctgctgagct ggtcttatca agcgcagcgc catcaccaca gccagtctta
    11281 gttcctcatc agatcattga aagagagtct acgcctttta ttgtttgatt taccgttaag
    11341 cctattccta agcaaagtac tgatagcttg cttaggaata aggcttttta tttaggaatt
    11401 tattttgttt gctaatagta ttaaagagaa gcaacgttta ctttagcatt ttcattgaaa
    11461 tcttcttaag aaaacgcttt acaaaacaaa aaaaggttgg taaaataagc ttatcaaaag
    11521 cgcaaacgtt tgcgttgaat gtgcttgttt ttaaaaagga attgagagtt catcagcttt
    11581 tagctggtta ttcttgattc ctagtccaaa aaaggagagg tcgaatgaaa acatcattca
    11641 aacaattttt tagcttcgag ttttggcaaa aattcgggaa atgcttgatg gttgtcattg
    11701 ctgttatgcc tgctgcaggt ttaatggtga gtattggaaa ttctctgccc atgcttaatc
    11761 aggagtcgca gcttttagcg acgcttggta atgtcattgc tcaggttggt tgggcagtta
    11821 ttggtaacct tcatttgctt tttgcccttg ctattggtgg cagctgggct aaggagcgtg
    11881 ctggcggtgc ctttgcttca gggcttgctt ttgttttgat taaccgtatt acaggggcta
    11941 tctatggcgt ttcttcagcc atgctgactg atccagaggc caagattaaa agtcttttgg
    12001 gcactgagat gattgtcaag gactacttta caagcgtctt agagtcacct gctctaaata
    12061 ccggtgtctt tgttgggatt atcgctggct ttgtgggtgc aacagcctat aacaaatact
    12121 acaattaccg taagctgcct gatgtgctgg ctttctttaa tgggaaacgc tttgttcctt
    12181 ttgtagttat ccttcgttca gctcttgtgg ccctagtatt agccttgatt tggccagtta
    12241 ttcagtctgg tattaatggc tttggcatgt ggattgcctc atctcaggac acagctccaa
    12301 tccttgcgcc attcttatat ggaacattgg agcgtctctt gctgccattt ggccttcacc
    12361 acatgctaac gattccgatg aactatacag ctcttggggg cacctatgag gtcatgacag
    12421 gagcagctgc tggaactaag gtatttggtc aagaccctct ttggctagcc tgggttactg
    12481 accttgttaa tctcaagggc tctaatgcgt caacctatca gcatttgatg gagactgttg
    12541 ttccggctcg ttttaaggtt gggcaaatga ttggtgcaac aggaacgctt atgggggttg
    12601 ccctagcaat gtaccgtaat gttgatgcgg acaaaaagca taaatacaaa atgatgttta
    12661 tctcagcagc ggcagcggta tttttgacag gggtcactga gccactggaa tacatgttta
    12721 tgtttgctgc gatgccatta tatcttgtct atgcccttgt tcaaggagct tcctttgcaa
    12781 tggctgattt ggtcaacctt cgtgtgcatt cctttggtaa tatcgagcta ttgacccgaa
    12841 cgcctatggc gattaaggct gggcttggta tggatttgat taattttgtc tgggtgtcta
    12901 ttctgtttgc tgtgatcatg tatgtcattg ctgactttat gattaaaaaa atgaagctag
    12961 caacagcagg tcgcctaggg aattacgatg ctgatatact agaaaacgat gatacaaagc
    13021 ctttgtcaca gcagtctatt gatggtcagt cacaggtcgt ccaaatcatt aatctcctgg
    13081 gtggacgtga gaatattgct gatgtagatg cttgtatgac tcgcttgcgt gtaacagtca
    13141 atgacccaag caaggttggc agtgaggagc attggaagca ggcgggtgct atggggctaa
    13201 tcatcaaggg cagtggtatt caggctgtct atgggccaaa ggctgatatt ttaaaatcag
    13261 atatccaaga cctgctagac tctggtgcag tcattccaga gccgaagcct gctcagcctg
    13321 ctgcctcatc atcacagcag acggacttta aaaacctaac agaggctgtt ttggcagtag
    13381 cagatggaga agtcttgcca atcacagcag tttctgatca ggtctttgca gctaaaatga
    13441 tgggagatgg ctttgctgtt gagccggcaa atggcgctat ctatgcgccg gtaacaggtc
    13501 tggtaaccca tgtctttcca accaaacatg cctttggctt gctgacagat agcggcctag
    13561 aggtgctggt tcacgttggt cttgataccg ttgacttgaa tggtgagccc ttcactgtca
    13621 aggttagtga gggtcagcgc gtatcggcag gagatctctt ggctgaggct gacctaactg
    13681 cgattacagc agcaggacgc aagacaacgg ttgttgtcgc ctttaccaat actacaagca
    13741 tcaaagctgt taaccttgtt gcgactggtc aacaaaaagc gaagaccctc gttgcacagg
    13801 tagagcttta agaataacca aagagagtgg tagatagcag tatgtcagac ctgcaggctg
    13861 ccacttctct tgtcgtatag gagaagatat gaccaagctc ttaaccctta acacacattc
    13921 ttggatggaa gccaatgcct taaaaaagct gttcgacttg gcagagcata ttttggctca
    13981 gaactatgac gtgatttgcc tacaagaaat caatcagctg attgacagcg aagcagcagt
    14041 gccattatca ggctaccagc caattgcagg gacacctgcc attcatcagg ataactttgc
    14101 cctcttgctt gtcaattact taaaaaaacg tggccaaagc tactactggt cgtgggccta
    14161 caatcatatt ggctatgata tttaccatga gggtgttgcg atcttatcca agcagccgat
    14221 ccaagcctca gacattttag tctcagcggt ggctgacgag tatgattacc acaccagacg
    14281 ggctttactg gccaaaacaa ccattgatgg cagggaggca gcagttgtga gcctgcattt
    14341 gtcttggttt gatcagggct ttgtcggaga atggcagcga ttagaggcag ccctgcagca
    14401 gctagcctgt cctgtgctat tgctgggaga ttttaacaat ccaagtggcc aagagggcta
    14461 tgagatgatt ctaaaaagcc ccttagacct tcaggatagt catcaggctg cagactacgt
    14521 ctttggagac catagtattg ttgctgctat tgatggctgg gaggataaca aagaggcctt
    14581 taaggtcgac catgtcttta ccagtaaggt ctttaccatt aacagctcaa aggtgacctt
    14641 tgatggtggt gaagcaccgg ttgtcagcga ccattatggc ctagaggttg acctcagctg
    14701 gaagctgtaa caaaaaaagc cagcaggact tgatagactg ctgacactgt aagaaacaga
    14761 tggttatctt agctcttaga agtaagctta tcgcaaggct tctaagagct tttttgcatt
    14821 tatatttcat gagcatatga gaaagttgca gacaaatgct ggacacataa tcagactgtg
    14881 ggctagttac atcgtctgct ctgatttgtg tcagatagtg atgatctgtg ctgccttgtg
    14941 attggccaga tatttacctc atatcaatag cagaaagtca agtctccctc agcctatctc
    15001 ctagcttacg attgctgatc atcagtcagt ctagctacaa ttacctgtgc caagcgctca
    15061 atatcagcac tggtcccgcg tagttcgaaa tctcccagca ttggaaagcc aaagcgctta
    15121 gcatactgct tggctgttag acaatactgg tgattgaagt ttttgttgcc agagccgata
    15181 atccctaaac aacgcttggc attatcatgc gccgcgataa agtctcccag cggattggtc
    15241 aagatttcaa cctcccctga gtcaatcccg tttcctcctt caagataggt cggcaaaata
    15301 gcaacaaagc tctccttgac tggaaaggtt tcgtgatgaa gctccttgat attgattgct
    15361 ttagtctgta tgtggtgctt ttctgccagg tattgcgaca agcgcctaac aaagctcagg
    15421 gtattgccgc taagactgat aaaaacaagg gtcaagtctg tcataaaaga ctcctttagc
    15481 aagattagtt tcctaaccag cttagcacaa tacccctgaa tacacaactc atatgacaat
    15541 gctctgcacg acaaacgcgc gaaacagtca tttccgaatg atagtataga cttaagcaga
    15601 tacattcacc gttttttcta tagtaaaagc tatagaaaat aagatatctt cttgaaatag
    15661 ctaaacattg acatacagaa agctttgttt tcttgctaaa accctatcat gcgtctgccg
    15721 tgcaatgctc tgacagctag cccactagtc acatcacata aaaaaggctt ggtgacaagg
    15781 acggtaagtc caaatcatca agtcttttta tggagagagc ttagtgttag ctgttacccg
    15841 aatcaagagg cccttgctgc taatgcttgc gattttgata ggtctttggg ctttctccgg
    15901 tatgcttttt gaaaaattta gaaaaatgtg agggatcagt gaagcccaac acgtctgaaa
    15961 tgtgattaat ggcataagca gagcgcagca atgtcttagc ctcttcaatt ttcatgtttg
    16021 aggtgtattg gtagatggtc aagcctgtat cacgcttaaa gatctgtctc agcttggact
    16081 cgctcatgtt aaaatgctgt gccagctcag cggttgtgac actcttatgc aggttgacac
    16141 tgatatattg gataatggca ttaaccgtag gagagacatg tttccagcgg ttgtcccgca
    16201 gctcactcac cttttgggtg taaaagacca gtgaggcatc acgaattttg agcacatctg
    16261 gcattgaggt tgccagctcg ctgtctctca tgaactcctc tcgtgaatgg taggcatcag
    16321 caatatccat accagattga atggcaatct gggctagtcg atcaaaggca atgatagaat
    16381 aatttttttc agagcgcagc gtatcaccac tcaccacagg gataaaggta tttcgtagac
    16441 tgaagatgat ttccttgagc ttgtgcacat caccctcttg aacaatgcta gataaatttt
    16501 tctcataatt gtagagacaa accttagatt cctgcttctt gacaaacata ttggcctttt
    16561 gcacctcgat attgtcggaa aaatccctaa tatagtgacg taaaggaggt gataacaaat
    16621 cctctatctt gccggaaaag aagtaatgga ccacaatcaa gaggtcacga atagcattca
    16681 aaggataaac aggtaaatgc tttagcgctt ggtaaagaat ctcttcttct tccttagtca
    16741 aatccttatc agcaacggcc accttaaaaa aggtcttatc caaaacatta cagcgccaag
    16801 ggccaattaa aatataatga tcctgataac ggtatattaa aaaaagctca ttatagcttc
    16861 cctgaaagaa aagattggtt gcctgttcct tgtccatttg cctaagcact gcttgaaaac
    16921 gataataaaa ttcaaaggta tcatcattcc aaaagctttc tgtcacctga tggtccttat
    16981 caaatactgt aattgataac ttcaaacagc cctgtagaga ttttactaac gacatagtat
    17041 ccatgctaag cgtcaccccc ttcataatcc tcacggtatc ttattctatc ttaaaattta
    17101 agaaaagcaa ggatatgcac ttataatgaa aaaatagaca taaaaaacaa taatatacat
    17161 tcttgcttat taaataaaaa tgacaatgta ctgcataaag aagttcctgt cattaaaata
    17221 aaagtgccat gaggttataa tagtatggta aaacaaaaaa gtgtgcccat aacgggtaga
    17281 gaggaattga catatgtttt tgagaaataa caagcaaaaa tttagcatca gaaaactaag
    17341 tgccggtgca gcatcagtat tagttgcaac aagtgtgttg ggagggacaa ctgtaaaagc
    17401 gaactctgag gttagtcgta cggcgactcc aagattatcg cgtgatttaa aaaatagatt
    17461 aaacgatata gccataagta gagatgcctc atcagcccaa aaagttcgaa atcttctaaa
    17521 aggcgcctct gttggggatt tacaggcatt attgagaggt cttgattcag caagggctgc
    17581 gtatggtaaa gatgattatt acaatttatt gatgcacctt tcatcgatgt taaatgataa
    17641 acctgatggg gatagaagac aattaagttt ggcttcatta cttgtagatg aaattgaaaa
    17701 gcggattgct gatggagata gttatgcaaa acttcttgag gctaaacttg cagttattaa
    17761 atctcaacaa gaaatgctta gagaaagaga ttcccaactt cgaaatctag agaaggaaaa
    17821 agaacaagaa ctacaaaaag ctaaagatga gcgtcaagct cttaccgaat cattcaacaa
    17881 aactttatca agatcaacaa aagagtataa taaactaaaa acagaacttg caaaagaaaa
    17941 agaaaaagca gctaagatga ctaaggaatt agcagataag ctaagcaatg ctgaagcaag
    18001 tcgtgataaa gcctttgcag tatcaaaaga tttagcagat aaactaagta gtgctgaagc
    18061 aagtcgtgat aaagcttttg cagtatcaaa agatttagca gataaattgg cagctaaaac
    18121 agcagaagct gaaaagttaa tggaaaacgt tggtagtcta gaccgcttgg tagagtctgc
    18181 aaaacgtgaa atggctcaaa aattagcaga aattgatcaa ttaactgctg ataaggctaa
    18241 ggctgatgca gagcttgcag ctgcaaatga caccattgca tcacttcaaa cagagctaga
    18301 aaaagctaag acagagcttg ctgtttcaga gcgtttgatt gaatcaggca aacgtgaaat
    18361 tgctgagcta caaaaacaaa aagatgcttc tgataaggct ttagtagaat cacaagctaa
    18421 tgtagcagag cttgaaaaac aaaaagcagc atcagatgct aaggtagcag agcttgaaaa
    18481 agaagttgaa gctgctaaag ctgaggttgc agatcttaaa gcacaattag ctaagaaaga
    18541 agaagagctt gaagccgtta agaaggaaaa agaagcgctt gaagctaaga ttgaagagct
    18601 caaaaaagct catgctgagg aactttcaaa acttaaagaa atgcttgaga agaaagacca
    18661 tgcaaatgca gatcttcaag cagaaatcaa tcgcttgaag caagagctag ctgacaggat
    18721 taagtcattg tcacaaggtg gtcgtgcttc acaaacaaac ccaggcacta caactgctaa
    18781 agcaggtcaa ttgccatcta ctggtgagtc tgctaaccca ttcttcacta ttgcagctct
    18841 tactgtcatc gctggtgctg gtatggctgt ggtgtctcct aaacgcaaag aaaactaagc
    18901 tatttcctct ttccccaatg gacaatagcc gaaataatag agcgactatc gttctaacac
    18961 aaaagcaaca gtctcctgtc tgttgctttt tgtgatatta gggctcatca gtctaggcta
    19021 atggttttct gcgctttatc tgcagctttg aggattcctt cttttgcttt tacagtgaaa
    19081 gtgttaaaat aggaaaaaca actagtaatt gaggaagtaa atggttaaag aaatcaattt
    19141 atcaggagag gaagtagttg cccttgctgc caagtacatg acagacggtg acgtcgagct
    19201 tgtgcaaaag gcgcttgatt atgcgacagc tgctcatttt taccaggtta gaaagtcggg
    19261 ggagccttat attgtgcacc ctattcaggt agcagcaatc ctagcagacc tgcatttgga
    19321 cgctgtgaca gttgtctgtg gctttttgca tgatgtggta gaggatactg atattactct
    19381 agaggacatt gagtttgact ttggtaagga cgttcgtgac attgttgatg gggtcacaaa
    19441 gcttggtaag gtagaataca agtctcacga ggagcagctg gctgaaaacc accgcaaaat
    19501 gctcatggcc atgtcaaagg acattcgtgt gattttggtc aagctagccg accgactgca
    19561 caatatgcgc accctcaagc acctccgtaa ggacaagcag gagcggattt ctcgtgaaac
    19621 catggaaatc tatgccccgc tagcccatcg cttggggatc agtcggatca agtgggagct
    19681 ggaggatcta gcttttcgct acctcaatga gatcgaattc tacaaaatct ctcatatgat
    19741 gagagaaaag cggcgggagc gcgaagcttt ggttgatgat attgtcacta agattaaagc
    19801 ctacaccacc gatcaagggc tttatggtga tgtctatggc cgtcctaagc acatctactc
    19861 ggtttaccgg aaaatgcgtg acaagaaaaa gcgctttgat cagatatttg acttgattgc
    19921 gatccgttgt gtcatggaga cacaaagtga tgtttacgcg atggtcggct atattcatga
    19981 gctctggcgt cccatgcctg gccgcttcaa ggactacatt gcagcgccta agaccaatgg
    20041 ctatcagtcg attcacacga ctgtttacgg gccaaaagga ccgattgaaa ttcagattcg
    20101 gaccaaggaa atgcatcagg tcgctgagta tggggtagca gcccactggg cctacaaaaa
    20161 aggtattcgt ggcaaggtca atcaagtcga gcaaaaggtt ggtatgaatt ggattaagga
    20221 gcttgtcgag cttcaggctg cctcaaatgg cgatgctaag ggctttgttg actcggtgaa
    20281 ggaggacatc ttttcagagc gtatctatgt gttcacaccg acaggagcag tgcaggaatt
    20341 gcccaaggat tcaggcccta tagactttgc ctatgccgtt cacactcagg ttggtgaaaa
    20401 ggcgacagga gccaaggtca atggccgcat ggtgcccttg acagccaagt taaaaaccgg
    20461 tgatgtggtg gaaattgtca ccaatccgaa ttcctttggt cctagtcgtg actggattaa
    20521 gctcgtcaag accaataagg ctcgtaacaa gattcgccaa ttctttaaaa atcaggacaa
    20581 ggagctgtct atcaataaag gacgtgagct tctggttagt tattttcaag agcagggcta
    20641 tgttgccaac aagtaccttg agcgtaagcg tattgaggag attttaccaa aggtcagtgt
    20701 taaaagcgag gagtctctct atgccgctgt tggctttggc gatattagcc cagtcagtgt
    20761 ctttaataaa ttaaccgaaa gagaaaggcg tgaggaggag cgtgccaagg ctaaggctga
    20821 agctgaggag ctggttaagg gcggtgaggt caagcatgaa aacaaagaga ttctcaaggt
    20881 ccgcagtgaa aatggcgtga ttatccaagg ggcgtctggg cttctcatgc gtatcgccaa
    20941 atgctgcaat cccgtaccag gagatgtgat tgaaggctat attaccaagg gacgaggcat
    21001 tgctattcac cgcgcagact gtaataacat caagagtcag gacggctatc aggagcgtct
    21061 cattgaggtt gagtgggatt tggagcattc tagcaaggat taccaagctg agattgatat
    21121 ttatggttta aatcgtatcg gcctgctcaa tgatgtcctg caaatcctat ctaacgccac
    21181 caagagcatt tcaactgtca atgcccagcc gaccaaggac atgaagtttg ccaatattca
    21241 tgtgagcttt ggcattccta atctggctca gctgacagct gttgttgaaa aggtcaaggc
    21301 ggttccagat gtttacagcg tcaaacgaac caacggataa aaaggagacc aaccatgaaa
    21361 attgtgattc agcgcgtcaa ggaagcctca gtgtcgattg atgggaaaat agctggcgct
    21421 attgatcaag ggctgctgct gcttgttggc ataggtccag atgatcaggc agaggatata
    21481 gactatgcag tgcgtaaaat cagtcatatg cggatttttt cagaccccga gggcaagatg
    21541 aaccgatcca ttcaggacat tgagggcagt gtcttgtcta tctcgcagtt tacgctatat
    21601 gctgacacca aaaagggcaa ccgacctgcc ttcaccgggg ctgctaagcc tgacagggcc
    21661 agccagcttt ataacagctt caacgctcag ctagagcagc ttgtaccggt tcagcgaggg
    21721 gtctttggtg cggacatgca ggttagtctg atcaatgatg gcccagttac gattatccta
    21781 gatacgaagt atcgataact gcctagcgat cgatcgtttg cttaggagag tcatataaag
    21841 gaaaaacaaa aagacgagtg gtatgagaag cactcgtctt tgtcgtttat gctgctgtgt
    21901 tgaagctagc tagggctact agtcttattt ttgcaggtct ttgtagactg cgatgaattc
    21961 tgtctcagaa attggggtta agctgccagt gaattggtaa gaagtaccat ttttagcttg
    22021 gaaagtatta ggtaaacctt taaggtattt gtcgatagtc tcagtggtaa ttgcttcgtg
    22081 tgttttaaag gtgtattcgt taatcagctg ctgctgtttg tcctgttggt aaatagtaac
    22141 tgaacgatag gttgtgctat agtcatcgtt aatatcctta gaaataaaat aggtttctac
    22201 aacagaatct gaatgtgtcg catagctaat gggattgttg acgtcatact ttgaattata
    22261 tacttgagct atcctgttag aatctatgat atagttaaag tcctcatcgc gatcagcatg
    22321 gtagaccatg cgttcactag ctccactgta aatctcaccg ttatggcttt gatgagttat
    22381 atcaggatcc tgcgtgactg ttgtactgat tcgcttgacg agctgatacc cgtctttgaa
    22441 agcctgagtg gtttcaaaag cctttttagc agcttcaaag agctcctcag aagagaccct
    22501 gctgccatag tatcttaacc cggtaagtcc ttctttacca aggctgtcag ttacatcaac
    22561 attaacaagc tgcccattgt cttttttgag gaatttaacg tgctgtgtca cagctacggc
    22621 atctgaatct tggattgggt ttcctgcctt atctgttacc ttaatgtcct tgagagctac
    22681 cttgctaact ttttccacaa ggacctgacc cgtcaagatg tatgtttggt ctttttgatg
    22741 atactgtcct ttgattggtg tcgtaaaatg gtctgtgcta agtatttcag ctgtagaagc
    22801 ttttgttaat ttggcatttt tcaaactaat gaccttaaag ctttctgctg aaggatctat
    22861 gacgtcttga actagcttta tcatctcatt tgtggtgtag gttttgccat attctagtct
    22921 aatatcctga taatgtggag atacgatggt gtgattagtg ttatctactc cagtgatatt
    22981 gaccatgagg tacagtcctg tggtttcttg atagtctttt gaatggattg gcttagtggt
    23041 gtcctcgtat ttatagtgat ttgctaccct actagagctt gaccatgccc acccaacttt
    23101 gtaatggttt gctttaacgg caggtgctcc caaggtcatg gtgaatagtc caatgactac
    23161 agttcctatt tctaaaggtg ttttcccaag gtgatacagt ctttttgaag tcaacatatt
    23221 tcaaacctcc ctaaatcctg tcagtctcta tagttataaa aatacagaga atcgttagaa
    23281 gaattaatgt ttcatgccgg caagatgagt gtaacaaaag attggtgccg atacaagaag
    23341 atggagatta gagcatctgg tttcaatgag agttacataa tagcagaagg ttttttcact
    23401 atgagagcta atcgtcttaa aatggtataa tagcaagtga ataggctatc taactggttt
    23461 aacagccatt tttagagaag cttaatagta ttgctgataa gtgactcgta tctccatatt
    23521 gcttttcaaa ggctatgtta gctatgataa gcgtgaccag gctatcggaa aatccagtgt
    23581 tcttaaaggc tttgaagctc tggctttgaa ccttagctct ggtgtttcta tgaaaatgac
    23641 ttgggccttg taccagataa gaatgaagtc aaattgaggt tttttgacaa aatgtttgag
    23701 taaatacaag ttcatagaag tctaatgtat aaaaatacaa ttgtatcgcc ataatctgaa
    23761 tgaccaaacc attaaaaaaa taaaattttt aaacattttg gaaaacgctt tcaaaactaa
    23821 aaagaactgt cctatagtca ttgcttagca ttaaagcaag gtgtgaaatg ttatcatatg
    23881 gagaaatagg ctgtcttgtg ctgtatctgt gccaaaaaag aatgcttgtt tttgtgatat
    23941 aatgtgacta agaaacctga aaggaatgct tatggcatta aaagactatt ttcctgatat
    24001 gcaagagggt gcatttcctc tggctgacca agattggatt agcgttgagg ttggggagca
    24061 gtacctccat ttccccaaat ccagcttgtc agagcgagag cagcttttgc ttggtttggg
    24121 gcggcagcgc aaagagccgt ccaaggatca gaaatctcct tggtatcatt atttgattct
    24181 gggccaaggg gagcagccgg aggagtttca gggttgccag ttcatctata tcaaccatca
    24241 atgtccttta gcaggtgatt tgattgagct tctaaagggg atcatagagg gagttgaggc
    24301 tgttttgccc attagccaga ccaggacagc ttttttggtc tgtcaccata gccgttcaga
    24361 cctttttcag ctcttagcaa atttattgcc cacgattgag agcgattttg gtttggcctt
    24421 gatgattttt atcggtaatg gctggtatca ggtgtcagga aatgccttga gagactattt
    24481 taaggaagaa aatgctgtgt ttacagctta tcttgctgag cactctgcca gtcgcttgct
    24541 gaccttttca gaggtcatgc tctggtcact cttagcaaac agtggtttgc cagccttgtc
    24601 aaagcatttt agtcagctgc ttttagccaa taaagaggtc atggatctgg tgctcgccat
    24661 gtggcaggag catggcaacc tggtacagac agcccagcgc ttgtatattc atcgcaattc
    24721 gctgcaatat aagctggata agtttgctca gcagtcaggt ctctatttaa agcagctaga
    24781 tgacttggcc tttgcttatc tatttatact gaagcattag atttgtgcag ggtgcccaaa
    24841 gacatttggg cgttttgtct atatgatgaa aacgctatct ttgctataat aaaagcatca
    24901 aataaaaagt gtcagggttg ctagcattgc agtcagctag cagcctatct gacccattag
    24961 gagtaacgca tggttgaatt aaacttaaag cacatctata agaaataccc aaataccaca
    25021 cactatgctg ttgaggattt cgatttagac attaaggata aggaatttat cgtttttgta
    25081 gggccttcag gctgtggtaa gtcaacaacg cttcgtatga ttgctgggct tgaggatatt
    25141 tcagagggtg aattgaaaat tgacggtgag gttgtgaatg acaaatcacc aaaggaccgc
    25201 gatatcgcga tggttttcca aaactatgcc ctttacccgc atatgaccgt ttatgacaac
    25261 atggcctttg gtctcaagct acgtaaatac aaaaaagatg atattgatcg tcgtgtcaag
    25321 gaagcagcag aaatccttgg cttgacagaa tttttagaac gtaagccagc agacctttct
    25381 ggtggtcagc gtcagcgtgt ggctatggga cgtgctatcg tgcgtgatgc caaggtattc
    25441 ttgatggacg agcctttgtc aaacctagac gctaagctgc gggtgtcaat gcgtgctgaa
    25501 attgcgaaaa ttcaccgccg tatcggctca acaacaatct acgtaacgca cgaccagacc
    25561 gaagcgatga ccttggcaga tcgtatcgtt atcatgagtg ccactaaaaa ccctcaaggc
    25621 aacggtacaa tcggaaagat tgagcaggtt ggctcaccac aggagctcta taacctaccg
    25681 gccaataaat ttgttgcagg ctttattgga agccctgcga tgaacttctt tgaggtggtt
    25741 gtcaaggacg gtcagatcat cagtgaggac gggcttgata ttgctattcc agaaggtcag
    25801 gctaaaatgc ttgaagcagc tggctataag ggcaagaagg ttatttttgg tatccgtcca
    25861 gaagatattt caagcaacca aatcgtgcat gacacctatc caaatgccaa tgtcacagca
    25921 gaggtcttgg tttctgagct gcttggatct gaaaccatgc tttatgttaa gcttggtcaa
    25981 acagagtttg cttcacgagt tgatgcgcgt gacttccaca atccaggtga aaaggttagc
    26041 ttgaccttca atgttgctaa ggggcatttc tttgatctag aaacagagca agctattcgc
    26101 taataacacc tcctagaata aaatcctcat cttgcttgag gattttttaa caaaagaaaa
    26161 tgcaagcgat tgcgctatca aaaagaaaaa gggatttatc ataaagacaa cagatgttct
    26221 gtagtgctag gcgatcataa tgatggcacg aaatagcagg agactgttta gtaataagga
    26281 gatatgatgg aaaaacactg gtggcataaa gcgacaattt atcaaattta cccaaggtcc
    26341 ttcatggata caagtgggaa tggtattggt gatttaaaag gaatcacagg taagctggat
    26401 tatctacagg agctagggat cacagctatt tggctgtctc cagtttatca atcaccaatg
    26461 gacgataacg gctatgatat ttcagactat caggccattg cagctatttt tggtgatatg
    26521 gctgatatgg acgagctgct tgatgaggcc aagcagcggg ggatcaaaat catcatggat
    26581 ttggttgtca atcacacctc tgatgagcac gcttggtttg tggaggcaag agaaaatcct
    26641 gacagtccta aacgagatta ttacatttgg cgtgatcagc ctaataatct catgtcgatc
    26701 ttttctggct ctgcttggga atatgatgat gcctctgggc agtattatct gcacatattc
    26761 agtaaaaaac agcccgactt gaattgggaa aatgctgaat tgcgtcaaag catttatgac
    26821 atgatgaatt tctggattga taaggggata ggtggctttc gcatggacgt cattgacctg
    26881 attggtaaga ttccggattc tgaaattaca ggcaatggcc caaggctgca tgaatacctc
    26941 aaggagatga accaggcaag ctttgggaat catgacctga tgactgttgg tgaaacatgg
    27001 ggcgctacac cggaaattgc tcgtcagtat tcacgtcctg aaaataagga gctgtcaatg
    27061 gtctttcaat ttgaacatat cggcttgcag cataagccaa atgcttctaa atgggattac
    27121 gcagctgagt tgaatgttcc ggctctcaag gagattttta gcaagtggca gacagagcta
    27181 aagctaggtg aaggctggaa ctcccttttt tggaacaatc atgacttgcc tcgtgtcgtc
    27241 tccatttggg gaaatgatac agtatataga gagaagtctg ccaaggcaat ggctattttg
    27301 ctgcatttaa tgcgtgggac accttatatt tatcagggtg aagagattgg catgaccaat
    27361 tacccctttg agcgcttgag tgatgtgaat gatattgaat cactgaatta tgccaaggag
    27421 gctatggcta atggcatgtc agaggaggct gttcttgatt gtatttgtag ggtgggtcga
    27481 gacaatgcaa gaacaccaat gcaatggagc agtcaaaaga acgccggctt ttcaactgct
    27541 gatcagacct ggctgcctgt caacccaaat catcaagaga ttaatgtggc tagtgctcta
    27601 gctgatcctg attctgtttt ttacacctat caaaagctta ttcagctgcg tcagacacag
    27661 gattggctgg tggaggcaga ttatcagctg ctggaaacat cagataaggt ttttgcctat
    27721 aagcgtcagc ttggtagaga gacttacctt gttgttgtca atctgtctaa tcaagagcag
    27781 ttttttgaag aaagtcttca taaggcccaa gtgattatca gcaataccga tgtgcaggca
    27841 gtcgtagaaa gtcaacagct ggagccttgg gacgcctttt gtgttaagct tgatgagacc
    27901 ttgtagccta gctgcttgct gtgcctcagc tcaataatcg tagcgattct ttgagaattt
    27961 tgacaaattg ctgtatgatt agtagaagaa ttagatacaa aagaggaggc tgagatgacc
    28021 gttgaagaaa ccatgacctt tgcaaaaagc attgcagcat ttagataggt agagattagt
    28081 gaggtagtca ctaggctagc agcaggtgag gacatcaccg tctttttagg cagagcgacc
    28141 tgtccttatt gtcgtcgctt tgcacccaag ctagcaagcg tagcaaggca ggagcataag
    28201 gatattttct ttgtagatag tgaagactca acagagcttg cagacctgca ggcctttcgt
    28261 gagcgctatg ggcttgctac tgtgcctgcc ctgctcatta gtcgtcatca ggaggtcaag
    28321 gcagtctgtg attctagctt gactgaggaa gccattttgg ctttcctaga gcagtgacag
    28381 acagctaatt atctggtgca agtaatagaa atgtaatcag tcatgtcttg ctatgtgagt
    28441 ccaaatctgc tatagtagga catgactttt agacgaaata aggagatatt atgggcttac
    28501 caacaatttt aatgtttgtt gtcatgattg gtttaatttg gtttatgcag cgtcagcaaa
    28561 aaaagcaggc gcaggagcgc caaaatcagc ttaatgcgat tgaaaaaggc gatgagattg
    28621 tgacgattgg tggcatgttt gcagtggtcg atgaggttga tttagcagca aagcgaattg
    28681 tcttagatgt tgatggtgtc tatctgccat ttgagctatc agcgatcaag cgcgtggtcg
    28741 aaaaaggaag tgcagtgaca tcagctgatg tggatacgac agagactgca gttgatgaca
    28801 cagcggttga ggcttcagac gaagctgaat cagctattga gacaaattaa gaaaatgagg
    28861 tctgaagcat tagtgtttca gactttttta ggtgatgata gcaggtagcc agacagagct
    28921 gtcatgtgct atggaaatat cgtctacaac gagaaaaagc gagccaaacc gcatgaaata
    28981 tggtaaaata tgaggtaagt atgcttgtga ataaggaaaa aacatgtttg gattaaaagc
    29041 gaagtcaaaa aaaatcgttt tggataggat tccaaagcac attgggatca tcatggatgg
    29101 taatggacgc tgggcgaaaa aacgcttaaa gccgcgtgtc tttggacata aggcgggtat
    29161 ggacgctttg caggaggtaa cgattgcagc ttcagattta ggggttaagg tgttaacagt
    29221 ctatgccttt tcgacagaaa attggtcaag accacaagat gaggtgagct tcattatgaa
    29281 cctgcctgtt gagttttttg ataagtatgt gcctgagctg cacaaaaata atgtcaaggt
    29341 gcagatgatc ggtgagacca accgcctacc taaggataca ctaaaggcct tggaagcagc
    29401 tattgctaag acaaggcaaa atactggctt gattctaaac tttgctctta attatggggg
    29461 tcgcgcggaa atcaccaatg ctgtcggtct cattgctcaa gatgtcctag acgccaagct
    29521 gaaccctggt gacattaccg aggatttgat tgccaactat ttgatgacgg atcatttgcc
    29581 ctatctctat cgcgatcctg accttattat cagaacgagc ggtgaattgc gcttgagtaa
    29641 ttttatgcct tggcaatcag cctatagtga gctttacttt acgccggtgc tgtggcctga
    29701 ttttaaaaga gctgaactac taaaggccat agaggattat aaccatcgtc atcgccgttt
    29761 cggtgctatt taaggagaga gtatgagaga acgtttcatt tggggtggtg ttgcagctgc
    29821 tgttttccta ccctttttac tcattggcag cttacccttt caattgtttg taggtgtgct
    29881 tgccatgatt ggtgtatcag agctgttaag aatgaagagg cttgaggtct tttcctttga
    29941 gggtgttttt gccatgctag cagctttcgt tttgacagtg ccgttggatc attacctgac
    30001 ctttttgccg atggacgcta gttttgcttg ttacgggctg ttggtgtttt tccttttagc
    30061 aggaatagtg attagcagcg attcttatgg ctttgaggat gctagctttc cgattgcagc
    30121 tagcttatat gttggtattg gctttcataa tctggttaat gcgcgaatga cagggataga
    30181 caaggttttt ctggctcttt ttattgtctg ggcgactgat attggagctt acttgattgg
    30241 gcgccgattt ggtaagcgaa agctcctgcc aaaaatatca cccaacaaaa caattgaggg
    30301 cagccttggt ggtatagtca gtgcggtgct tgtttccttt gtgtttatgc tctttgataa
    30361 ggctgtttat gctcctcatc attttggaac aatgttgatt ttggtggctc ttttttctat
    30421 ttttgctcag tttggagatt tggttgaaag tgctgtcaaa agacatttcg gagttaagga
    30481 ctcaggcaaa ttgattccag gccatggtgg tattttagat cgttttgatt cgatgatctt
    30541 tgtttttccc attatgcatc tatttgggtt attttaaagc tcattatcaa tagactgaaa
    30601 ggaaatctat gttaggaata attaccttta ttattatttt tggtattctt gtgcttgtcc
    30661 atgagtttgg ccatttctat tttgctaaac gatctggtat tttagtcaga gagtttgcta
    30721 ttggcatggg accaaaactc ttttcgcatg ttgatcagca aggaacgctt tacacgatcc
    30781 ggctattacc gcttggtggc tatgtgcgaa tggcaggctg gggtgatgac acaactgaga
    30841 taaaaacagg aacgcctgct agcttaacgc ttaatgatca gggcttggtc aagcggatta
    30901 acctgtctca gagcaagctt gatccgacta gcctgcctat gaatgtgact gcttatgact
    30961 tagaagataa gttgacgatt acagggctgg ttcttgatga gatcaagacc tattcggtag
    31021 accatgacgc gaccattgtc gaggaggacg gtacagagat ccggattgcg ccgcttgatg
    31081 ttcagtatca aaacgcaagc attggcggtc gtttgatcac caattttgca ggacctatga
    31141 ataattttat tctaggtatt gttgtcttta ttttgtttgc ctttgttcaa ggtggtgtgg
    31201 ctgattatca tagcaaccat attcgtgtgg tggaaaatgg cgcagcagcc aaggctggta
    31261 ttagagacaa tgatcagatt ttagagatta atcatcaaaa gattaatgac tggtatgagt
    31321 tgacgcaggc cgttactgat tcagcagcag atgttaaggc taagggcaag ctagagatta
    31381 cctatcagac aggtgatcag gttaagacta tagcactgaa gcctgaaaaa aaaggcgatc
    31441 agtaccttat tggtgtccag tacccactaa aaacaagtct gacagacaag ctaataggtg
    31501 gctttgagat ggctggtaat ggtgctctag tgattgtcac tgctctaaag agtttgatta
    31561 cctcctttag cctagataaa ttaggtgggc cagttgccat gtatcagatg tccaatcagg
    31621 cagcaaagaa tggtttagag tctgtcttgt ccttgatggc aatgctctct atcaatttag
    31681 ggatttttaa tttgattccg attcccgcac tagatggtgg taagatcctg atgaatgtga
    31741 ttgaagcact tcgtcgtaag ccattaaagc aagagacaga gacttatatt acccttgcag
    31801 gtgttgcgat tatggtggta ctcatgattg cagtgacctg gaacgatatt atgcgagcct
    31861 ttttccaagg ctgatggtct ctctcattta aaggagagcc taaaaggctt aatgtaacag
    31921 aaataacaag agatatagtg tcattattgt ggttctaaga ccttgcaaat gcagcaaaag
    31981 cttagccaat atagctcatt ttgtctcttt tttagaaatg aattctcaac gaaaggaaag
    32041 agagctgttg accaagctgg gctaaggcct acagctgaaa tcaaaatgct agacctgcta
    32101 ttagtctaag ggcgttttga gctgctctct atagcttatt ttaatgaaac aaagtaaaat
    32161 gcttatccca accctgcgcg aaatgccaag tgacgctcag gtaatcagtc atgccctcat
    32221 ggtgcgtgcg ggctatgtcc gtcaggtatc tgccggtatt tatgcctatt tgccattagc
    32281 tcatcgtaca attgaaaaat tcaagacgat tatgcggcag gaatttgaca aaattggtgc
    32341 tgttgaaatg ctagcacctg cccttttaac agctgacctc tggcgtgaat caggccgcta
    32401 tgagacttac ggtgaggacc tttacaagct aaaaaaccgc gacaaatcag actttatctt
    32461 aggtcctacc catgaagaaa cctttactac actggtgcgt gatgcggtta aatcctataa
    32521 gcagctgccg ctcaatctgt atcagattca atccaaatat cgtgatgaaa agcgtcctcg
    32581 taatggcctg cttcgcacac gtgaatttat catgaaggac ggctatagct ttcatcaaag
    32641 ctatgatgat ttagatgtca cctatgacgc ctatcgtcag gcctatgagg ctatttttac
    32701 cagagcaggc ttggatttca aaggaattat cggtgatggt ggtgctatgg gtggtaagga
    32761 ttcgcaggaa tttatggcta tcacaccgga ccgtactaat ttagaccgct ggctggtctt
    32821 agacaagtct attccgtcat tggctgacat tccagaggag gtcttggaag agattaaggc
    32881 cgagctggct tcatggctgg tttcaggaga ggacaccatt gcttattcaa gtgaatcaag
    32941 ctatgctgct aaccttgaga tggcaaccag tgagtacaag tcctcatcaa aggtaacagc
    33001 cttagatgat ctcgtcgaga ttgagacacc aaattgtaaa accattgatg aagtggcggc
    33061 ctttcttgac gttgctgagc atcaggtcat taaaaccctg ctctttatgg tggaccatga
    33121 gcctgtgctt gctttattgg ttggaaatga ccagatcaat gctgtcaaat tgaaaaacca
    33181 cctcggtgca gacttcttag agccagctag cgaggaggag gcgcgtgcta tcctaggtgc
    33241 aggctttggt tcacttggtc cagttcattt gacagatggt atccgtattg tggctgatcg
    33301 taaggtccaa gaccttgcta atgctgtagc tggagccaat aaagatggtt atcacctgac
    33361 tggtgtcaat ccaaatcgtg atttccaagc agagtatgct gatattcgtg aggtaaaaga
    33421 gggagagacc tctccagata gacatggcgt gctgcagttt gccagaggta ttgaaatcgg
    33481 tcatatcttt aagctgggga cccgctattc tgatagcatg gcagctaata tccttgatga
    33541 gaatggcaga gcagttccga ttgtcatggg ctgctatggt attggggtta gtcgtatcct
    33601 atcagcagtc attgagcagc atgctcgtct ctttgtcagc aagacaccaa agggtgatta
    33661 tcgctatgct tgggggatta atttccctaa agagctagct ccgtttgatg tgcatttgat
    33721 taccgttaat gtcaaggatc aggaggcgca ggacctgaca gaaagagtag aggctagtct
    33781 gatggccaag ggctatgatg tcctcactga tgaccgcaat gagcgtgtcg gctctaagtt
    33841 ctctgatagt gatttgattg ggcttccgat tcgtgtgacg attggtaaaa aagcagctga
    33901 gggcattgtt gagatcaaaa tcaaagcaac aggtgacagc attgaggtgc acgctgatag
    33961 cttgattgaa actcttgaca ttctcacaaa ggacaactaa tgatatgagg tcaacgatgg
    34021 ttgatctctt tttgtatgct ataatgaaag catgacaatt gaggaattac agcagctggt
    34081 gctagcagat catgagctaa tgactattct aagcattata gagaccttgc ctttaaagga
    34141 ttgttggctg gcagcaggtg caattcggaa cgctatttgg aatcatttag cttatgggat
    34201 aggctttgat ccgctgacag atgtagatgt ggtctttttt gaccctgaga tctcttacga
    34261 agctgagcag ctgctagaag agcagcttaa gtgtgcttat cccatgtacc aatgggaggt
    34321 tcgcaatcaa gcctatatgg cagcacataa ccccaagacg cctccttatc gatctagtca
    34381 agacgctatc acaaagtatc cggagcgctg tacagcgatt gctgttagac ttgtaggagg
    34441 acagctagag gtttttgctc cctatggttt agcagacatt agtcactttg tctgtcggcc
    34501 aacaccgcat tttttagagg attcagagcg tatggactgc tataggcagc gcctagcaaa
    34561 gaaggactgg cacaagaaat ggccacagct gacctaccac gactgctaag tcagaggaaa
    34621 caaagcaggc taggagctcc gtacagccaa gcaattagtc cgctcccaga cccgttagct
    34681 acagctctca cctagtcaaa acaagcacat gaacagatca ttggcagata gccttgcctt
    34741 tgcagatatt gtcacaccct atttagctgt accatgtgtc ttatgatagg cgtgatagtg
    34801 ctgtcagaag cgccagctga gccagaaaaa gcgttaagcc tacagcaagg ggcttttaac
    34861 ctttggtatg ttgtcttgta ggagaggtcg aaaatgatca ctatttatga taaaatagac
    34921 cctaagaaaa tcaggagaaa gctatgtcag atttattcgg taaattgatg gaacaaattg
    34981 aaatgccact tgagataaga caatcaagtg ccttttcgtc tgctgatatt atcgaggtca
    35041 aggtgcattc agtgtctcgt ctgtgggaat ttcatttttc ctttgcagag gttctcccga
    35101 tagagagcta tcgagagctg tcagataggc ttgtgagaac ctttgaggca gcagatatta
    35161 aggtaacatt tgacatcaag gcagagacaa ttaattattc ggatcagctg ctgcaagcct
    35221 actatcaaga agcatttgag catgagccct gtaatggggc tagcttcaag tcatcttttt
    35281 ctagacttca ggtcaggtat gaccatcatc agctgatcat tatggcacct gactttgtga
    35341 ataatgatca ctttaggaaa aatcatttac ccaatctggc agctcagttt gagcgctttg
    35401 gctttgggag gctagcgatt gatatggtgt ctgatcagga gatgacagac catttgacaa
    35461 aggactttga gaccaaccgt caggctctgg tggaaaaggc tgtacaggat aatatcgcag
    35521 cacagcaatc attggaggcc atgcagccac cagctgagga ggcagcacca agcccaagcc
    35581 ttgactatag agagcgtatg gctcagcgcc aagcaagctt tgataaggcg gtcattacac
    35641 caatgattga ggtggataca gaagaaaatc gcattgtttt tgaaggaatg gtctttgatg
    35701 tggagcgcaa gacgacaaga acaggccgcc atatcatcaa cttcaagatg acagattaca
    35761 cctcctcctt tgccatgcaa aaatgggcca aagatgacga tgagctcaga aaatttgatc
    35821 tgattgcgaa gggagcttgg ctgcgcgttc agggaaatat cgaaaacaac cccttcacca
    35881 agagcctaac catgaatgtg cagcaggtta aggcgattgt tcaccatgag cgtaaggatc
    35941 tcatgccaga agggcaaaag cgtgttgaat ttcatgcaca cactaatatg tccacaatgg
    36001 acgctctacc gacggtagaa gacctgattg atacagcagc caggtgggga catcaggcag
    36061 tagcgattac tgaccacgct aatgttcaga gctttccgca tggctatcat agagcacgca
    36121 aggcaggaat caaggcaatc tttggcttag aggccaatat tgttgaggat aaggtaccta
    36181 tttccttcaa tcctgtcgct atggacctgc atgaagccac ctatgttgtc tttgacgtgg
    36241 agaccaccgg cctttctgcc atgaacaatg atttgattca gatcgcagct tccaaaatgt
    36301 tcaagggaaa tatcattgag cagtttgatg agtttatcaa tccaggccac cccttatctg
    36361 cttttacaac agaattgaca gggattacag ataatcattt ggtaggagct aagcctatac
    36421 agcaggtgtt agaggcattt caggcctttt gtcagggcac tatcctagtt gcccacaatg
    36481 ctagctttga cgtgggattt atgaatgcca actacgatcg gtatggttta gcaaaaatca
    36541 gccagccagt tattgacacc ctggagcttg ccagaaacct gtaccctgag tataagcggc
    36601 atggcttggg ccctttgact aagcgctttc aggttagcct tgagcaccat cacatggcca
    36661 attacgatgc tgaagcaaca gggcgtttgc tctttatctt cctaaaggaa gctagagaaa
    36721 agcatgggat tacaaacctg cttcagctca atacagactt agtggcagag gattcctata
    36781 agaaagcacg gatcaagcac gccacgatct atgttcaaaa tcagctaggt ctcaaaaaca
    36841 tgtttaagct ggttagcctt tcaaatgtga aatattttga aggtgtgcct agaattccaa
    36901 gaaccgtcct tgatcagcat cgtgaaggct tgctgcttgg gacagcctgc tcagacggcg
    36961 aggtctttga cgctgttttg acccaaggaa ttgacgctgc tgttgatctg gccaaatact
    37021 acgattttat cgaaatcatg ccgcctgcaa tttaccagcc cttggtagtc cgagagctaa
    37081 tcaaggatca agcaggagtt gagcagatta ttcgcgattt gattgaggtc ggccgcagag
    37141 ctgaaaagcc tgtcctagct actggaaacg tgcactacat tgagccagag gacgccatct
    37201 atcgtgacat tatcgttcgt agtctagggc aaggtgccct gattaaccgt actattggcc
    37261 gcggagaggc tgccaagcct gtcccgctac cagaggctca ttttagaaca accaatgaaa
    37321 tgcttgatga ttttgccttt ttaggtcagg acttggccta tgaggttgtg gtgcaaaata
    37381 cccaagccct tgctgatcga attgaaaagg tggaggttgt taaggatgat ctgtacaccc
    37441 catatattga taaggcagaa gaaaccgttg ctgagctgac ttatcaaaag gcctttgcta
    37501 tctatggcaa cccacttcca gatatcattg atctgcgcat tgaaaaggag ctaacgtcca
    37561 ttttgggaaa cggctttgcg gtgatttatc tagcctcaca aatgctggtt aatcgctcta
    37621 atgagcgtgg ttatctggta ggctcacgtg gctctgttgg ttcaagcttt gttgcgacca
    37681 tgattggcat cacagaggtc aatccaatgc cgcctcatta tgtctgccca agctgccagc
    37741 agtcagagtt tatcacagat ggctcggtcg gctctggcta tgatttgcca aacaaggcct
    37801 gtcctagatg tgggacgctg tacaaaaagg acggacagga tattcctttt gaaaccttcc
    37861 ttggctttga tggtgataag gttccagata ttgatttgaa cttctcagga gatgatcagc
    37921 ccaatgccca cttggacgtt cgtgatatct tcggggaaga atacgccttt cgtgcaggta
    37981 ctgttggtac tgtcgctgaa aaaacagcct atggctttgt caagggctat gagagagatt
    38041 atggcaagtt ttacccagat gcagaggttg atcgtctagc tgctggtgct gctggtgtta
    38101 agcggacgac tggtcagcac cctggtggga tcgttgttat ccctaactat atggacgttt
    38161 atgattttac acctgtgcag tttccggcag atgatgtgac agcctcatgg cagacgaccc
    38221 actttaattt ccatgatatt gatgaaaatg tcctaaagct cgatgtactc ggtcatgatg
    38281 atcccaccat gattcgtaag ctgcaggatt tatcaggtat tgatccgatt actattccag
    38341 cagatgatcc tgacgtgatg gcactttttt ctggaacaga ggtgctcgga gtgactcctg
    38401 aacaaattgg aacaccaaca ggtatgcttg ggatcccaga gtttggaacg aactttgttc
    38461 gtggcatggt gaatgagacc cacccaacga cctttgcaga attgctgcag ctatcaggtc
    38521 tatcgcatgg aacggacgtc tggctgggta atgctcagga tctgatcaaa gaaggcattg
    38581 ccaccctaaa aacagttatc ggttgtcgag atgacatcat ggtttacctc atgcatgctg
    38641 gtctagagcc taagatggcc tttaccatca tggagcgtgt gcgtaagggg ctctggctaa
    38701 agatttccga ggaggagcgc agctcctata tcaaggccat gcggcaaaac aacgtcccag
    38761 actggtacat cgaatcctgt ggtaaaatca agtacatgtt ccccaaggct cacgctgccg
    38821 cctatgtttt gatggcattg cgagtggctt atttcaaggt tcatcacccc atcatgtatt
    38881 actgtgctta tttctctatt cgtgccaagg cctttgagct caaaaccatg agtggtgggc
    38941 tagctgctgt caaggctcgc atggaggaca tcagcaacaa gcgcaagcgc aatgaagcct
    39001 caaacgttga aaatgacctg tttaccactt tagaaattgt caatgaaatg cttgagagag
    39061 ggtttaagtt tggcaagcta gacctttaca agagcgaggc aactgagttt caaattgaag
    39121 gggataccct aattccacct tttattgcct tagaaggctt gggagaaaac gttgctagac
    39181 aaatcgtcaa ggctcgccaa gatggtgaat ttctatcaaa aatggaatta cgcaagcgtg
    39241 gtggtgcttc tgccactcta gttgataaga tggacgagct gggcatttta ggaaatatgc
    39301 cagatgacaa tcagctgagt ctatttgatg actttttcta agattgcaca gccctaatat
    39361 tgtctatgtt agcttgtcat acagtgaaga gcagggcagg aaggcttcct gtcctctttt
    39421 tgtcaatacg caaagaaagc ccaaaaaaga acgaggaaaa gcatgaatga attagacaaa
    39481 aatcctgcct taaaggcaat ggttgttttt agaaaagcac agcgtacctt agatgctcaa
    39541 agctccgcct tttttcaaaa ggccaatctg actcctaccc aatttagcgt cttagaggtg
    39601 ctttattcca aaggaagcat gagaattaac aagctcatcg gttctctctt ggcaacctct
    39661 ggcaatatga ccgtagtgct gaaaaatatg gagagaaatg gctggatcag ccgctgccaa
    39721 gatgctaaag ataagcgtgc ctgcttggta cagctaacgc cagagggcaa agccttgatt
    39781 gagactatcc tacctgagca tatcaaacgt gttgaagccc ttttttcagt gctgacagag
    39841 actgagcaaa aacaattgat tacgctttta aagaaattta aagaactcta agcaaatggc
    39901 tttacaggat ctcccaagta ggatataatc actacatagt acaaaaagat actaactagt
    39961 cataataagt catcaagaca gcagatggct agttaccaga taatcaatgg gagacaaagc
    40021 atgaaacaaa ttttaatcat taatggttca ttacggacag gttcatttaa tcatcagctt
    40081 gctcaagcgg ctgagcagct acttgaaggc aaggcagctg tatcttactt ggactgggaa
    40141 caggtaccta tgtttagtca ggatttagaa gcaagcaccc ctgagtcagt ggcaggcgta
    40201 cgagaagcca ttcaagcagc agatgctatc tggatttttt cacctgtcta taattttgca
    40261 atcccgggct ctatcaaaaa cctattagac tgggtatcac gcgcccttga tttgtcagac
    40321 ccatcaggac catcagcaat caatggtaag gtagttaccg tatcatctgt tgctaatggt
    40381 gggcacgagc agctatttgc gcaataccag gacctgctgc cctttatccg tacgacagta
    40441 gttggtaact ttaccaaagc cgctgtcaat ccagaagcat gggcgacagg tgttcttgat
    40501 atttctgagg aaacaaggca aagccttgca gcacaggcag aagcccttct tgaagccatt
    40561 cactaagact ctctgagcat taaacagata aagctgcagc taggatcaaa aagcagctag
    40621 acacataaaa agagcttaaa ccagaaatgt acggcactcc aaaagctaga caaaaactct
    40681 agcgattggg gtacaggtca aaacggtttt aagctctttt ttagacttat tttatagtag
    40741 taacttaatt aagaattagc ataccctctt tagcctcaaa ggggtttttc gcattaatac
    40801 ggtcatagaa taagacacca ttaatatgat caatctcatg ctgaaccacg atagcattgt
    40861 agccctttag cttaatgcgg tgcttttcat tgtgcttatc gtaatattcc actgtcacac
    40921 gcgcatgacg gacgacatag ccttccacca cacgatcaac agacaaacac ccctcaccgt
    40981 cagcaagagc agcgtcttga acagaatgag acacaatttt aggattatag agcacttcct
    41041 ccatgctgta agcctcctta ggtggattgc cctcgctgtc ttcaggattt ggaaccagaa
    41101 cagcgatgat acgctttgac acatcaatct gaggtgctgc tagaccaact cctgctcgaa
    41161 gccctaattt ttctcccatg acagggtctt gagaatgctt taaaaattgc atcatttttt
    41221 cacctaaaat gatgtcatca tcactaagag gaaactcgac ctccttagcc acagcacgaa
    41281 gcgtaggatt gccttcgcgg ataatatcat tcatatcaat gagatgctgt gctttaatta
    41341 atttatcttg tgcagacatt ttgcctccct ttttttatat ttgataatgg ctttactata
    41401 tcacaaaatc cttattttta aaagataagg caggccagtg atgacgatat tagctaactc
    41461 tatcagatat attaaattat ttaaaaaata gttcgttaat tagcacgaca tatatataag
    41521 aaatacacag gaattctaat aattaataga taaaaaatga taatcgttcg taaataaatc
    41581 aaacatctaa tctaaaaaaa ttatattgtt ctgattgttc ggtaattaaa gcaatagcgc
    41641 ttgtcgaaaa actaatgttc tcttaatatc aggtagccat gccaagggtt ttgtgttaaa
    41701 gtataggacg ttcaaaaaat gaaatggaga gactaatgag aacacaattg aaaaaattgc
    41761 tggcaggaac agcagcaggt accctgctgc tgtttaacct gacctgcgga atgattaatg
    41821 cttttgcaga gcagtattac gggtggagtg acgggagtag cagctatccg agtgctttgt
    41881 atgttacacc ggtaggagat actacgaaaa agatagctat tcctgtttat tgctttgact
    41941 ataagtttca ggagccactt gcttggaaag aaataactca accgtcacac ttgattgtct
    42001 atgataagta tgatggcaaa aatttgatgg cagcactggt tgaaaaacct aatatggtaa
    42061 gctatgagac taaaactaaa cttcaaacac ttttaaagac aaagtcaaat ctaataactg
    42121 caattttaag tagaggttat ccaaacaaaa gtttttttga taagtataaa aaattaactg
    42181 atgaagataa aagacgagtg acacaatgtg ctctttggta tcatactgac aatatttcag
    42241 aacaagatct tatcacaaaa catttggatg gggattcagg tgaaaaaagt caagcgctaa
    42301 aggagttaat aggggttgta aaaaatactt ctaatgagtt aggagaggga ttaaccttct
    42361 atactcgtta taatgataga tatggtccta aatatcaaaa cctaataggc tcaattattg
    42421 ttcccgaaga gcctcagaat gatcttgaaa ttggtggtgg aaatgttatt gatttaaact
    42481 accaatctgg accaatggta gaagaaggtg gtcattcagg tggcaaggaa gaggtcgagg
    42541 acactaaaaa gcctgatgtg attattggtg gtcagggaag cgttactgag actactgagg
    42601 atactcaaaa gggtatgagt ggcagtactg agactcagcc agaggttgag gatactaagc
    42661 agccacaatc agatattatc ctaggcggac aaggcaatgt gattgacaca actgaaaata
    42721 cccaagaggg catgggtggc caatcaggtg atactacaga gactgaggat accaagcagc
    42781 cacaatcaga cattatccta ggtggacagg gcaatgtaat tgacaccact gaaaatactc
    42841 aagagggtat gagtggttcc aacaatggtc aaacatttga ggaggacaca cgtcctaagc
    42901 tggaattcca ttttgataat gaagtgccta acgatgatga cgctcctaaa ccagagcaac
    42961 cagaacagcc agagaagccg gagcaaccaa ggaagccaca gcaggagcag caaagcctac
    43021 cacgtccaat agagggcaac cagtcattgc caaaaacaca tgaggcaaaa ggtgtactgg
    43081 ctctagtagg agtaggaatc cttgctatgc taggactagg cttttggttt agaccttatc
    43141 aaaaagacta aatcaaggct cagcagctat ttaagctaaa cagctgtgct cagctaaatg
    43201 ataaaacaat taagattgga gaatgtggct attagtagct tctccaatct tttttgatag
    43261 cagcatgtgc tttttctgcc gtattttatt gagaataata gttgaccagt ctaggcgatt
    43321 ttgctagaat agagaggtcg caagacagac taactttttc ttggttttag gagtgccaac
    43381 cctaaaactc ggattaagca aaaaaggaga attattatgg caatctcaaa agagaaaaaa
    43441 aatgaaatta ttgcacaata tgcacgtcac gaaggtgaca caggctcagt tgaggttcag
    43501 gtagctgtcc ttacttggga aatcaaccac ttgaacaacc acatcaagga gcacaaaaaa
    43561 gaccacgcaa cttatcgtgg attgatgaaa aaaatcggac accgtcgtaa cctattagca
    43621 tacctacgtc gtacagatgt taaccgttac cgcgagttaa tccaatcact tggacttcgt
    43681 cgttaattgg cttgacagag gtcattttag agataaccaa gttctattga aaaaagatct
    43741 gct
//
LOCUS       DARYXZ010000015        39689 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYXZ010000015 DARYXZ010000000
VERSION     DARYXZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39689
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..272)
                     /locus_tag="TV186_000699"
     CDS             complement(<1..272)
                     /locus_tag="TV186_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1532114.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKG"
     gene            complement(309..1685)
                     /locus_tag="TV186_000700"
     CDS             complement(309..1685)
                     /locus_tag="TV186_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1532115.1"
                     /translation="MLTMKHKMLIFCLLLSIFVSQFHMLHVYAETSSKTQYNILIKES
                     LDTNKVKKQLNDQGMIVLDEIPEINVLTIAAANDSSMILEKNCNYIDDISRNNTFTVN
                     PKMTYQFGHAFYLDSDLNYWNKQWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNT
                     DISSKIISVQNFTEDPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMY
                     KVFEEGNAQDEWILKAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAI
                     NYAHKQGSVVVASVGDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVT
                     VGSVDGDGAISNFSNRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLE
                     GKYTYGYGTSIAAPKVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLL
                     NITDFISK"
     gene            complement(1853..1984)
                     /locus_tag="TV186_000701"
     CDS             complement(1853..1984)
                     /locus_tag="TV186_000701"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532116.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(3093..5039)
                     /gene="thrS"
                     /locus_tag="TV186_000702"
     CDS             complement(3093..5039)
                     /gene="thrS"
                     /locus_tag="TV186_000702"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL1532117.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(5630..6964)
                     /locus_tag="TV186_000703"
     CDS             complement(5630..6964)
                     /locus_tag="TV186_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1532118.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(6966..7964)
                     /locus_tag="TV186_000704"
     CDS             complement(6966..7964)
                     /locus_tag="TV186_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1532119.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(8260..9735)
                     /locus_tag="TV186_000705"
     CDS             complement(8260..9735)
                     /locus_tag="TV186_000705"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1532120.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(9805..10806)
                     /gene="ccpA"
                     /locus_tag="TV186_000706"
     CDS             complement(9805..10806)
                     /gene="ccpA"
                     /locus_tag="TV186_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL1532121.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            10980..12065
                     /locus_tag="TV186_000707"
     CDS             10980..12065
                     /locus_tag="TV186_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1532122.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSILPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(12239..13822)
                     /locus_tag="TV186_000708"
     CDS             complement(12239..13822)
                     /locus_tag="TV186_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532123.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            14060..14911
                     /locus_tag="TV186_000709"
     CDS             14060..14911
                     /locus_tag="TV186_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1532124.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            15172..15840
                     /locus_tag="TV186_000710"
     CDS             15172..15840
                     /locus_tag="TV186_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1532125.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            15955..16881
                     /locus_tag="TV186_000711"
     CDS             15955..16881
                     /locus_tag="TV186_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1532126.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(16865..17053)
                     /locus_tag="TV186_000712"
     CDS             complement(16865..17053)
                     /locus_tag="TV186_000712"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532127.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(17165..17632)
                     /gene="smpB"
                     /locus_tag="TV186_000713"
     CDS             complement(17165..17632)
                     /gene="smpB"
                     /locus_tag="TV186_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL1532128.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(17635..19959)
                     /gene="rnr"
                     /locus_tag="TV186_000714"
     CDS             complement(17635..19959)
                     /gene="rnr"
                     /locus_tag="TV186_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL1532129.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(20046..20282)
                     /gene="secG"
                     /locus_tag="TV186_000715"
     CDS             complement(20046..20282)
                     /gene="secG"
                     /locus_tag="TV186_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL1532130.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(20328..20474)
                     /gene="rpmG"
                     /locus_tag="TV186_000716"
     CDS             complement(20328..20474)
                     /gene="rpmG"
                     /locus_tag="TV186_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1532131.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            20962..22794
                     /locus_tag="TV186_000717"
     CDS             20962..22794
                     /locus_tag="TV186_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1532132.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPRG
                     ENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPS
                     TITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKRKRKQ"
     gene            23106..24146
                     /locus_tag="TV186_000718"
                     /pseudo
     CDS             23106..24146
                     /locus_tag="TV186_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
     gene            complement(24309..24902)
                     /locus_tag="TV186_000719"
     CDS             complement(24309..24902)
                     /locus_tag="TV186_000719"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL1532133.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(24899..25720)
                     /gene="mutM"
                     /locus_tag="TV186_000720"
     CDS             complement(24899..25720)
                     /gene="mutM"
                     /locus_tag="TV186_000720"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL1532134.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            complement(26135..27934)
                     /locus_tag="TV186_000721"
     CDS             complement(26135..27934)
                     /locus_tag="TV186_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1532135.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            complement(28095..32735)
                     /locus_tag="TV186_000722"
     CDS             complement(28095..32735)
                     /locus_tag="TV186_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL1532136.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            complement(32908..34255)
                     /locus_tag="TV186_000723"
                     /pseudo
     CDS             complement(32908..34255)
                     /locus_tag="TV186_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(34320..35636)
                     /locus_tag="TV186_000724"
     CDS             complement(34320..35636)
                     /locus_tag="TV186_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1532137.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            complement(35629..35961)
                     /locus_tag="TV186_000725"
     CDS             complement(35629..35961)
                     /locus_tag="TV186_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1532138.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            complement(35971..36288)
                     /locus_tag="TV186_000726"
     CDS             complement(35971..36288)
                     /locus_tag="TV186_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1532139.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            complement(36312..37211)
                     /locus_tag="TV186_000727"
     CDS             complement(36312..37211)
                     /locus_tag="TV186_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL1532140.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            37391..38593
                     /locus_tag="TV186_000728"
     CDS             37391..38593
                     /locus_tag="TV186_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL1532141.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            complement(38756..39232)
                     /locus_tag="TV186_000729"
     CDS             complement(38756..39232)
                     /locus_tag="TV186_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1532142.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(39377..39586)
                     /locus_tag="TV186_000730"
     CDS             complement(39377..39586)
                     /locus_tag="TV186_000730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532143.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
BASE COUNT        12038 a         9432 c         7309 g        10910 t
ORIGIN      
        1 aatcctttaa taatatcgtc ttcagtatct ttagcactaa caaagataat aggagaagca
       61 actttatctc ggattaattg acaaatttgt gtaccttcaa cattaggcat catgacatct
      121 aataaaatca agtcaaaccc ttgaaaatct ctaaaattga ttggaaaagt cacttcttga
      181 taggttgtta ccttgtaatt tttcatctca agaatggtcc gcataagttt taaaatctca
      241 taatcatcat caacaactag aatcttatac atagtcttac ctcataatag ttacactgtt
      301 attttacact attttgagat aaaatctgta atatttaaca atctaattgg ttttccatta
      361 tcatccaagc tactccaaga gttactatac aaaatagtta tggcctcatc tggtttatct
      421 tttaaatcat atttttcgat gattaaacct aaggcagcag ctactttagg ggctgcaata
      481 gaggtcccgt agccataagt atatttccct tctagtgttg ggataataac ccaatcttgc
      541 tcaaataatt tattgttaat ccaagtgtca tagccatgaa gcgctagctt cttgcttcct
      601 ccacctgccg caaagatatc aacgacattc cttccacgat tggaaaagtt agatattgca
      661 ccatcaccat caacagatcc tactgtcaca acattatcta gctgtgcggg aatatcctct
      721 attgtcccat cgactgaact aaacgctctt cctgtgagag cactgactaa gttcttaagc
      781 tcagcttgat tatttaagtt agctccctca tcaccaacag aagcaactac cactgagcct
      841 tgtttgtgtg cataattgat tgcccgttga tagctattga ttagagcagt tctatcttca
      901 tcaatatttg atgaagcctt taataaatac tgaccaagac tcaaatttat gacatcaaca
      961 tcatcctttg ctgcttgaat aattgctttt aaaatccatt catcttgagc gtttccctct
     1021 tcaaacacct tatacattct aaccttcatg cctggagcaa ttcctgtata ataaccattt
     1081 gaagacattt gtccaacaac agatgtacca tgacctgttt tatccaaaac attattaaca
     1141 tcaattgcct tagttactgg atcctccgta aaattttgaa cagaaatgat ctttgaagaa
     1201 atgtcagtat tattatcagt aataccagaa tctattacac caatggttac ctcacctgat
     1261 gacttatgcc aaaacctact actagtacta atacttcttt gcatatccca ttgtttattc
     1321 cagtaattta aatcactatc taaataaaat gcatgcccaa actgatatgt cattttggga
     1381 tttactgtaa aagtattatt ccttgaaatg tcatcaatat agttacaatt cttttccaaa
     1441 atcatagatg agtcatttgc agcagcgatt gtcaaaacat taatttcagg aatttcatca
     1501 agcactatca ttccctgatc atttaattgc ttttttacct tattggtatc taagctttct
     1561 tttataagaa tattatattg agttttgcta ctagtctcag catagacatg taacatatga
     1621 aattgagata caaaaataga cagtagcaaa cagaaaatca acattttatg cttcatggtc
     1681 agcactcctt taagtattgt ttttacactt atcgtatgac taacatttca gatttgtttc
     1741 agattctaga aaataatact tactattgtg cttatttaag tccaaaaatt agcattacac
     1801 tcattaagta tctgagatta atctagctaa cattctaaat tgttttctcc cactaatctt
     1861 ttgttcttaa ttccgactta taattaaaga caaaagctaa tttttctaac tgcctcgcat
     1921 agcactcata cttgccaatc attgttgtca tcgtctcctg attgagctta gtttcttctt
     1981 ccacctgctc cagtttacta gctgatatgc aagtgcaatg gtcgtttttt gtgaatcaca
     2041 cctactttga atctggtaaa atcattctac taacaaactt cctgtgtaat ttctagtagc
     2101 ctaggtagcc tgataaagag atttcttcaa ataaaaataa ccatgtcgaa tgccagcgct
     2161 ccatttctta ccagcatttt cattattccc cagctaaagc tctatccatg aggctaagtg
     2221 acctgtgctt agaattaact catatccaca ctagtctcag aaataaagac tgaagctatc
     2281 atgatgtcac tactaggaat gaatgaaatc tagggtttct acttgacagt catagtgaga
     2341 caaacaagcg gcaatttgct cttctaaact cccgatttgt ttctaatagc aagcataaat
     2401 ctccatagac tacccccata gaaaatggtg gtgattggag aaatcaccat taagtgcttc
     2461 acgacgttga ggagctttct tcttcaaact agtataaaca attaatggac tacttactct
     2521 agctgtcata ggcgtttgag caatcagtag ttgaaatagc ttgcaaccga aagcacccag
     2581 catactctca atgcggatcg gaagttcaat gccacctaac tgtagaattt tataatgcaa
     2641 attgtccttt attaagaacc ttattgatca ttttaagctt tagttcggga gaggaacgaa
     2701 tctttttcct tagcagcttt acaatcaatt aatcgtgcta aatactttaa atggaattga
     2761 ttgatatcaa attgtttgaa tgaataactc tggttttgta ggccgcagat ttctaccttg
     2821 tcttgatgtc ttaatgtcat gttaaaagca ccccattcgt tagatagttt gtctaacttt
     2881 tggggcgcag ttcattcatt agatttttta tctaattttt gagaagcagt ttacttctga
     2941 tgagggcttc tatattgctt tcattagttc tatgagtgag agcaaagctc ttgtagctat
     3001 ttgtcccaga tttttttatg tcatctgttt tgcaagtcaa gctgacgtct gcttaatcag
     3061 cctatctaaa accagcttgc ttggtctgct ttttagcctt cagctgggcg tgatttgcgg
     3121 gcaatatcag ccaaaatgtt atcaacaaat gctgaaatag cttcggtatg tgttgcctta
     3181 ctgccatagc ggcgcacatt aactgacttg tcctgcatct ccttatcacc aacgattaat
     3241 tggtaaggga ttttactggt ttgagaggca cgaatcttat attgcatttt ctcattacga
     3301 tcatccacat ctgcacgaat cccatgatca cgaaggattt tagcaacctc ccaagcatag
     3361 tcaatatggg cctcattgga aattgggata actgttacct gacgtggtgc cagccatgtt
     3421 gggaaagctc ccttataggt ttcaatcaaa atagcagtaa agcgctccat ggttgaaatc
     3481 accccgcggt ggatcatcac cggacggtgt tcttctccat cagcaccaat atagctcaga
     3541 ttaaaacgct caggcagtaa gaagtccagc tgaatggttg atagggtttc ttcatttcca
     3601 agggctgttt tgacctgaat atcaagcttt ggcccgtaaa aggcagcctc tccttctgct
     3661 tcaaagtaat cagcgcccat ttcatcaagc gcagccttca gcatgctttg agcattttcc
     3721 cacatctcat cgttatcgta atatttatgt gtatcctttg gatcacgata ggacagacgg
     3781 aagcggtaat ctgttaggtt aaaatcctca taaacgtcaa taatcagctg aagagctcgc
     3841 tggaattcct cctgaatctg ctctggcgtc acaaacaggt gcccatcgtt taaggtcatc
     3901 tcccgcacgc gctgaagccc tgaaagagcc cctgattttt catagcggtg catcatacca
     3961 agctctgcaa tacgaatcgg cagctcgcga taggaatgca catggttttt ataaacctga
     4021 atatggtgtg ggcaattcat tggacgaagg acaaattctt caccatctcc catatccatt
     4081 gtcgggaaca tatcctcctg ataatgctcc cagtggcctg atgttttata aagctcaact
     4141 gaagcaagcg gcggagtata aacatgctga tagcctgatg ccagctcttt atcagtgata
     4201 tagcgctcaa gcgtgcgacg aatcgtcgct ccatttggta gccaaaatgg caagccttgt
     4261 cctacctcct gagagatcat aaacaaatca agctccttgc ctagcttacg gtgatcgcgc
     4321 tccttagcct cctcaaggcg tgtcaaatag gccttgaggt cctttttatc aaaccaggct
     4381 gtcccataga cacgctgcat catgttatta tcgctattgc cacgccagta agctccagct
     4441 acatttaaca aatgaaagac ccgaatccga cctgttgacg gcacatgagg accacgacaa
     4501 aggtccacaa attcaccctg acggtaaaca gttaagccag ccgcatcatc tgcatgctca
     4561 ttaatcaact caaccttata agggtcatcc ttaaaaagct caagagcctc ttcttttgtg
     4621 atctcctcac gaatacatgg aaagttctct ttgacaattt ttttcatttc ctcttcaatg
     4681 cgaggcaggt cttcgttaga gatttgacca tcagcattat ctgtatcata ataaaaacca
     4741 tctgcaatgg cagggcctac accaagatgc agcttgggga acaagcgctt agcagcttga
     4801 gcaaacaagt gagccgcaga atgacgcagc acctcaaaag cgtcctcatg atcagcagtt
     4861 ataatttcta tactaccgtc ctcttcaatg gcgcgcgtgg tatcaattaa ttgaccatta
     4921 aacttaccag ccaaggcctt tttagctaga gatttgctga tagagtcagc aatctcaaag
     4981 gttgtgacac cagattcaaa ttcacgcacc gcgccgtctg ggaaagtgat tgtaatcatc
     5041 tgttttctcc tataaaccat ctagatactt aaaacaagct aatcaagcag ggctatatct
     5101 cccaagcctt ctgctgctac gacaaaataa aaactgactg cctcccaaag gacgcaatca
     5161 gcgtggttcc acctttattt atgcatgaca aagaaatcct gtcctgcacc tcagcttggc
     5221 tatatcgtga ccaccgtttt atgtttgcat aaaagcaagg aaggagtatt acactagaca
     5281 ccctgtgctc ttctcaccaa ccagcactcg cttaaaggat gcgacctaat ctaacttgtc
     5341 ttcctgatta ttatagcaat atttggaaat aattcaagtg atttttccta aaaaagctga
     5401 gataagccca cagacctcca agcccacaag gcaagaatga ctaggcaagg aaccctgaaa
     5461 cttctgccac aagcctttga agaacagctc aaacaggact tgccgcctgt cgtctcagtt
     5521 cacaagacaa caaactaaat cctttagaca aatgattatc ctaaagagct atctgctctc
     5581 tcacgcagaa ccaaagcctg taattgcagg cttctttgtt tatttagcct tagtccaaaa
     5641 agtctcggat cgcattgacc agcttgatag gggctttgag caccttgaca gatgtcagtg
     5701 cagttgcctt agctgctcgc ttaggcaagt gaatcgctcc ttgaaccagc ttgattgagc
     5761 cactcttttc tgttcgattg agatagagac ttagcttttt cgtctcttta ttgtgtcgcg
     5821 aaatcaaggt atctaaataa aaggtgtaca ctgatttgcc aaaatgctga gctgaaatct
     5881 catagcgctt ctcatctagc agcctctggt tcatttgagg tgtttctaaa atggcatcaa
     5941 taatcgcatc tgacaattct gactcagcat aataaagtgt tccaaacatc ttatcggtaa
     6001 tcaaatcatc taggtaggga ttgccatgag cgatgatggg cttgccacta gcaaggctct
     6061 caatataagt tagcccctgt gtctcactcg ttgacgctga aataaagaaa tcacaggcct
     6121 tataataaag cccaacctga tcatgagcaa tcataccagt aaagaccaca tgatcctcaa
     6181 cgcctaagct gacagccagc tcctttaagg cttgaagata aggaccatca ccaacaatga
     6241 caagcttgat cctgctattt tcactcaaaa cagctggcag ctgatggata atagcctgaa
     6301 tattcttctc ataagacacc cgcgacaggc tcaatagcat ggtctcatca tcagaaatgg
     6361 ccaattcctt tctcaaggca gcgacatctt cttttttaat atcctcacga acatagttct
     6421 ctagtgcaat gccagtcgga atcacacgct taggaatggt tacctcgtac ccttccaaaa
     6481 gatttagcac aatccgactt gggcaaataa caccatcaag gtcctttaaa tacccacgaa
     6541 gcaggggctt gaccatgcta ggtcgaatga tcttaccatt agcaatatag ctcacataat
     6601 cctcatactg ggtatgatag gtgtgaacaa ccggaattct taaggccttg cccaccattt
     6661 tgcccaacaa acctaagcta aactctgttt gagtatggat aatgtctaaa tgatattcct
     6721 tagcaatctt gtaggaggaa atgagcccac gataaaccac acgacgatcc gtaaaggaca
     6781 caaaaggaac acttggtaac cgaataatgg tcggatcctc aaagcgctta acatgcttgt
     6841 ctgttgttgt gaaaatatag acctcatgcc cctctttttc cagctcctcc tttagggtgc
     6901 gaatactggt agccactccg gaaacctgtg gaaaataggt atctgtaaat agacctacac
     6961 gcatcttata actccattac tttttgataa atagccacta attgatgagc aatcctatca
     7021 aggctgcgcc cctcggcgac acgatagccg gcctctgttt tgttgctttc ccctgaaaga
     7081 atgcgtctta aggctgcaac aaagcctgag gtatcatttg ccaactcagc actgtcttga
     7141 tcaatccagc cctcatagac tggtatatcg cgtaaaacaa gatgctgccg gctggctaag
     7201 gcttcgagaa ccacaatgcc ttctgtttcc tcacgacttg ggaagaaaaa ggcgtcagcc
     7261 ccagtcatag ccccctcata cacatctccc ttgatataac cagggaagat cacattatcg
     7321 gggtgcttac cgttgacaat ctggcggaca cgagcaggaa taacccattt attggtatca
     7381 ccaaaccaga taaaccgaac atctggcatc atctcagcaa ccttaacaaa ctcatcaatc
     7441 ccttttctaa gaaagaaaag ccccgctccc atgactacct tctcaccctc tttgaggtta
     7501 aaataacgcc gaaaggcagc ttctttgtca gcattagcac catattgctc caaatcaatc
     7561 ccattagata ctgcaaaaat aggagtctta accccgtaat gctcaatcaa ggctttagaa
     7621 taaggggtcg gtgtgataat ggcgtccgcc ttattgtaaa agcggcagag ataggctttg
     7681 aataaaggag acactagatt tgaaaaaata aaggaatttc taaaatcctc ctctgtcgaa
     7741 tgcccatgca tgatcacctt tttaccggcc ttttgagcct ttgacatcaa aagccagctt
     7801 ttaagcccat aggtattgag atgaaccaaa tcatagtcgt cctttggatc agtggtgaac
     7861 tcctgtccca caagcgatag cgcttttgcc tgatgcttaa tcgctcgccc gatacctgat
     7921 tttcttaaat aattttctgc ttctaaatac aataagactt tcatactgtc tattatagcc
     7981 tattttatgg tatttttcac taagagagtt aaaaatcagc ccttagactg attttagggt
     8041 aaggcttctt ctacccctat actcatctca aaaatgcttt taagtcctgc ttttgctgtc
     8101 atcaaatggc tgatcttggt aatatcagct agaccaagat cgtgaaagct ccagctcaag
     8161 gctcacgtat tagccctttc aagaaagcct cccacctttc tcactggcca aaaagccagc
     8221 aagacctggc cttttcttct gattaattca gcctatcagc taagcttctt cttttggctg
     8281 tgctttttgt aacacccagg ctgagataga gcctgcctct accttgaaat ctgcccagcc
     8341 atcctcagca acaacaacag tctcctgaca attgtctaag aaatcacaaa aaacttgacc
     8401 agcataggct tgaccaacct ccatgtgctt ccagcctgca tcgccattag acaaaacaac
     8461 tgccaaaggc tgaggacgct gatcatctcc taagcaggtc cagccgatac aattggcatg
     8521 atcaaagtaa tcaatctgct ccccatagac cagctgctgc ctgagctctg ccatttttgt
     8581 gataacctcc ttaaaacttt gctgagggta gtctccagaa ataccataat aatcaccata
     8641 aaaaagacag ggcttgccct cttgtcgtaa aagaatcagg ccataggcta agggcttgaa
     8701 ccattcctca acagttgact ctaaggcttg ccctctttgg gtgtcatggt tttccacaaa
     8761 ggtaatagca aggtctggcc gactagccac aagactgcca tcaaaaatag tggtcaaatc
     8821 aaaatcagct ccctgctggc tagcattaaa aaaggacatg tgcagcgcaa catcaactag
     8881 agcaaactga gccttcgttg cttcgaggta atcctccata gattcctgat cagacttcca
     8941 gtattctcca aaaacctcta aatcgggctt tagctgggta cgaatatcat tgataaaggt
     9001 ctgaataaaa taagaatcaa tatgcttcac agcgtctaaa cgaaagccct caataccagt
     9061 tgtctcaata aaccacttgg cccaatcctg taaattttgg attacctcag gatgcttgaa
     9121 atctaagtca ttgtacatta gataatcaaa attaccatgc tcatcgtcaa tcagctcatc
     9181 attggcccag cccttgttat caccggtgat catgtaaata cctgtttcat tagccttggc
     9241 gtcataatcc aatcccgtaa aatggtacca gtgccattta aagtcattat aggtattttg
     9301 tctgccggga aaatcaaagc ctgtccagcc ttcaatctca tagggctctg taagggcctg
     9361 ctgacggttc tctggattca ttttgatcac agaaaagcgt tccttgtgat caccattagc
     9421 cttgtggttc agcacaacat cagcaatagg ctttattttt gcctctttta gggctgcaat
     9481 cagctgcaaa taatcctctt tgctgccata ttttgtgctg acagttccat tttggttaaa
     9541 ctctcccaaa tcaaacaaat cgtaaacacc gtaccccaca tcatcagagc tagtgccctt
     9601 aaaggcaggc ggcagccaca gctgactaac ccctagctgt tgtagctcag gaatactgct
     9661 tttcagcctt tgccaatgcc ttccatcggc aggcaaatac cattcaaagg cctgcattaa
     9721 tagttgatga ctcatcttaa cctcctaaaa aggacaaacc agaaaactcc tagtttgtcc
     9781 tcaaaactgc ctaaacaggc agaactattt tgttgtccca cgctttttaa tgccatggtt
     9841 caataaaatt tctttttctt ctaattcttc cttattcatg atcttagtga gcatacgcat
     9901 gctaacagcc cccaagtcat agaccggctg gctgatagag ctcaaatttg gacgtgtgta
     9961 ctgaacgact ggagaatcat tgcttgtgat aatctcaaag tcttctggaa cacgcttacc
    10021 agcttcaaaa agaccattca aaaggcctgc tgccagctcg tcctctgcaa cataggcagc
    10081 tgtcgctccg gaattgatca cacgctgagc cagctcaaag ccttccttat aagaatagtt
    10141 ggcctcaaac accagaccct ctttaaagtc aagcttgttc ttcttgagtc cgtccttgta
    10201 gccagctaaa cgcacctttc cgttgatatc atcaatgagc ggccctgaaa caaaggcaat
    10261 gctttggtgg tctttagcta aaatatccac cacatcagca acagccgcct tataatcaat
    10321 gttaacactt ggcagctgat gatccagatc aaccgttcct gccagaacga ttggcgtacg
    10381 cgaacgagaa aactctgccc gaatcttgtc agtcaagtga tgtcccatga aaataatgcc
    10441 atcgacctgc tttgcaaaga gggtattcac aacattgacc tctttatcat cgtcctcatc
    10501 acttgaagca agaacaatat tgtacttgta catagcagca atatcatcaa ttccctttgc
    10561 cagaatagaa aaatagctat ttgcaatatt aggaatcaca acaccgactg ttgttgtctt
    10621 tttacttgca agaccacgag caacagcatt tggacgataa tcgagacgat caataacctc
    10681 taagaccttt ttgcgggtat tttcctttac atttttgtta ccatttacaa ctcgactaac
    10741 tgtcgccatt gaaactcccg cttcgcgagc aacatcataa atcgtgattg tatcatctgt
    10801 attcattctt catcttcctt tctaactgaa aatgacgctt tcaaaaagta ttttagcatg
    10861 atttgtaacc actttcaagt attaacggtt gatttttgaa aaagttttca aaaattcata
    10921 ataagcttgc ttttttaagt attttttgga aaaatagaag gcagaaagaa ggtttatcta
    10981 tgactaaatt agatcaaatt cgtttgtacc ttaatcagga aaaggctgag cttgctatct
    11041 tttctgattc tgtaacgatc aattacttaa ctggtttttt atgtgatcct catgaaaggc
    11101 agatgttcct atttgtctat catgacaagg ctcctgtttt gtttgtacca gctttagagg
    11161 ttgcaagggc tgaacaattg ctggacttcc ctgtttttgg ctacgttgac tctgaaaatc
    11221 cttgggaaaa aatcaagtct atcctaccaa gcacagcagc aaagaccatt tacgctgagt
    11281 ttgatcattt gaacattacc aagtttcaag ggctgcagag tgtcttttca ggacgctttg
    11341 acaatctaac cccttacatt caaagaatgc ggctcatcaa gtctgctgac gaaattcaaa
    11401 aaatgctgat tgctggagaa tttgccgata aggctgtcaa tgtgggcttt gataatattt
    11461 cacttgacgt caccgagaca gatatcatcg ctcaaatcga atttgaaatg aaaaaacaag
    11521 gcatcagcaa gatgagcttt gaaacgatgg ttttaactgg taacaacgct gcaaacccac
    11581 atggcattcc aggaaccaat aaaatcgaaa acaatgccct gctgctcttt gaccttggtg
    11641 ttgaaacatt aggctatact agcgacatga cgcgtacagt tgccgttgga aagccagacc
    11701 aatttaagct tgatatttat cagctttgct tagaggctca gctaactgct cttgatatga
    11761 ttaagccagg agtgactgca gctcaggtag atgccgctgc tcgccaagtg attgaaaagg
    11821 ctggctatgg cgactacttc aatcacaggc tcggccatgg tatcggtatg gacgttcacg
    11881 aatttccatc aatcatggct ggcaatgacc tgattcttga agaaggcatg tgcttctcag
    11941 ttgagcctgg tatctatatc ccaggcaagg ttggggttcg tattgaggac tgtggtcacg
    12001 taactaaaga cggctttgag ctcttcaccc aaacaccaaa agaattacta tactttgaag
    12061 ggtaatagga ggcttaaaaa gcctgaaaca aaatgtctca gaccctaata tctaaagcaa
    12121 cagcacttgg tctgttactt ttcatattac aggctatttt ctcacaagga aaagtcaaag
    12181 caccccttga tgggaaatca gaggggcaaa agctatttgt actaagctca aaagctaatc
    12241 aagagcacct gaccagctct ttatccttta agtgataaat gcaatcataa gactgtgcat
    12301 tatatttatg agctatctca accatggtgc aggggagtga atggagtaac tcacgaatct
    12361 ctctggcgct ttctttgtct agggcagctg tgacctcatc agccagcaaa atcggtttta
    12421 gtatcagcaa gcagcgtgca atttccagct tcatgatttg cccgccagag agattttgcc
    12481 catctagatg gagatcaaga tctccgttta gctcattcca aagatgaacc tgctgtaata
    12541 tctcctttag tcgctggtcc gaataatcct gaaacagcgt gagattatct cgcaagcttc
    12601 cttcaaatat gtaaggcttt tgatgtatca aagacacaac atcataggaa ggaaaatagc
    12661 gttttccatt ggcagcttca aaataaatag ttccagaata atccttatcc tcaccacaca
    12721 aaagagcaaa taaagtagat ttcccactac cactggctcc tgttagcaag gttttgtgcc
    12781 ctgctgaaat atgaccatct atcccttgaa aaataagcct atgatcaaaa tacttatcta
    12841 acctcttaaa gtagatatca agtgtaagat catctgtagg ggttaaggct tgatgttttg
    12901 tctcttcctc cagagccaat actctaacca tcttctcctt aacagcagtt gcagactgta
    12961 aactcgaagt agcttctaat aattgctgca agggagagac aagattcgta gaagctgtta
    13021 tcatagcaat gagagttgtt agtgatagac ttgaatagct catcaccaac agaccaataa
    13081 taagaggact aaccaagcca atccctttta atggaccagt ccaaaacatt accagattgt
    13141 gggtagtata atagctatat tgcttgtctt ccatatgctg aatcatttct aacacatggt
    13201 gagcaaaagc ttcgttggct tgattactct gtatcgtgtc tgccccctta gtaaaatcgg
    13261 tgatactggc taggcttttc tccctcgcct gactaagctc taagcctcgt gattgaagta
    13321 agtgattgaa cacaaactgt ggaataatca tcaaaaagcc accaatagta aaggcaatac
    13381 caatataaat atcctgcaaa agaaggtaca agacagaggc taagatagat aggccaaaaa
    13441 caggataaat gaataagggg accaaatact cctgccaaaa cataggaata tcttgggtca
    13501 aaaacgaatt taaggctgaa gtaaaatagt tgagctgttt atgataaaaa tgatataaag
    13561 ccttctttgc aataaggcaa ttaaacgctc taaccataga acgtgctaaa atgttattaa
    13621 gatacatgca catataaata aagacaaaaa aagctacgcc tccaagacca aaaagcaata
    13681 ccattccttt attgttcata tcaatttgcc ctgctatctg aattaatact gataacaata
    13741 gtccctgcaa ggaatagagc aaagccaata aactatacaa gcaaagctgc cattttgaaa
    13801 tgacttgtaa aatacttttc atatcaatca ctcctcacct gaaacctaaa tgtatcgctc
    13861 tcttggaaag tataaacgaa acatcctcat acaccaatca tttccaccac aaactagatt
    13921 cttgaatgtt aaatcaagct cttgatcaaa atcatgttct ctgatttctt gaacaaccat
    13981 tggttctctc ctttcattct tactatttct agtatataat gggaaaaaat acgaaaggaa
    14041 aaatttcgga aatccggata tgaatatcag agagaaattt aaagcaattc gtaaacaaag
    14101 aagactatcc ttaaaaacgc ttggtaaaat agctggctca gccactagta tttctgactt
    14161 cgaaaatgga aaaacgaacc tttctaatga tgttttattg cagcttttag gctttatgat
    14221 tgttgaaata aacgagctat tcgaatggga ggattttcac gaaaaggaat tggttgaagc
    14281 catcaagcaa atcgaactgg caataaaatc taaacatatt cctgctctat ctcagctaca
    14341 gcaggacttt caaagcttat ctaagacaaa ggaacagtac atttaccaca tcatctcact
    14401 gatcctaacc atcaccattg cagaatatca aaacaaagag atcgatccac acatcatgtc
    14461 tgagctaaca gactacttct ttttcttgga gtattggact aaccttgatg tcggcctact
    14521 aggaaacatc gtccactaca tgacaacaga tgccctaatc ttattgacaa atgacatctt
    14581 agagcatacg cctcaagtac tccgaaataa cctagatcgt attaggatcg atactgtatt
    14641 aaactgtctt actgtcttga ttaatcgtaa agaggagaag gcaagcagaa cacttcttaa
    14701 attattattt aacaaacatt atcctaatta ctttgccttt gaaaagctct atttacatga
    14761 attacaagca gtctatgatt ttaactggaa agataaagaa caggcgcttg cagctcatca
    14821 cgtcatactg gctaccattt cattactatt tacagctgat gaagccaaag aatgggacag
    14881 cttctttcaa gaaagtacta gctctttgta atactccagc tcatacacta aagaaaagca
    14941 aggataatca cataaaaact aatcacatca ctttgccctg ctagctgaat tagcttgggt
    15001 catctcttat gcccagcaaa acatcatcta gtctcagctt tcttccaaag cttcttgtct
    15061 ctctgggctt gcaagctttt gatagcttaa gaggcacaag cattaacaaa ggctaacaaa
    15121 tgcctgtaaa aatatgctat gataggggta acaaaaacct aggaggtgct tatgtcacac
    15181 aaatccattc atcaacagct tagaaatgct ttttcctttc ggacagcggt acgcgtctac
    15241 aatgaccaaa aaatagccaa agaagactta gacctgattt tagatgctgc ctggctcagt
    15301 ccttcctcta tcggccttga ggcctggcgg tttgtcgttt tagaaaacga agctgtcaag
    15361 catgagctaa aggaggtctc ttggggagca gtttatcagt ttgagacagc tagtcatatg
    15421 atccttttaa tcagcgaaaa aaacgccaga tatgatggcg cttctatcaa gcaaagctta
    15481 ttgcgcagag gcattactga cgagcaagcc ttggccagtc gtctggcatg ctacgaagcc
    15541 ttccaaaagc atgatatgaa aatagcagat gatcctcggg ctctctttga ctggactgcc
    15601 aagcaaacct atatcgcgct tgctaatatg atgaccactg ctgcttttat ggggattgac
    15661 tcttgtccga ttgagggctt taactatgac aaggtaaatg ctatcttagc aaaacatggg
    15721 attatcaacc ctgataccga gggtatctct agcatgctgt ctttaggcta tcgcctgcgc
    15781 gatcccaaac actcacaaac cagaaagccc agagaagagg ttatttcctt ctttaactaa
    15841 gccccttttg ccattgctcc caaagaaagt gcaaagacag tcctttgcct tttctttttc
    15901 ataactgtcg aattatggta caatgtgtca aaagacctat ggaaagtgat gcctatgaca
    15961 ttattatctg taattatccc ctgcttcaac gaagaagaca cgattattcc ttatcttgaa
    16021 gaaatgaagc aaatcgaagc ggccatgacc agccaattag cctttgaata tctttttatt
    16081 gatgatggct ctacagatca aaccctgagc gtgctaagag agcttgcggg gcgcttctct
    16141 aatgtgcatt acctctcctt ttcacgacat tttggcaagg aagctggact attagccggc
    16201 ctagaagagg caaaaggaag ctatattacg gtgatggacg ttgacctcca ggacccaccc
    16261 gagcttctcc cgctgatgta tagcaaatta caggagggct ttgatgtggt tgccacaaga
    16321 agacagagcc gacaaggaga gcctgctatc cgttcctttt ttgctagact cttctacaga
    16381 ttagtcaagc atgtctccaa caccgaaatc gtcgatgggg tacgtgatta tcgtttaatg
    16441 acaagacagg tggtggatag tattttagag ttgggagagg tcaatcgctt ttccaagggg
    16501 attttttctt gggttggcta caatactgcc tatatcagct ttgacaatcg taagcggcag
    16561 tacggcaaaa ccagctggaa ctttcttgag cttttgaact actcgataga cggctttatc
    16621 aatttttctg agatgccctt aaccattgct acctggactg ggacacttag ctttttgcta
    16681 tctctgctag ccatttgctt tattgttata cgcaagctgc tttttggtga tccggtttca
    16741 ggctgggcaa gcactgtatc cattatgcta tttatcggtg gaattcagct gttttgcatg
    16801 ggaatcattg gaaaatacat ttccaagatc ttccttgaaa ccaagaaaag acccgtctac
    16861 atcatcaaag aaaagaaata acagagcaat catcaaggcc cctatcagcc gccaatgagg
    16921 ccgataagga ctggttgccc tcatcatgac aagcacgaca aaaagacttg atggtcccaa
    16981 tcaaaaccat caagtctttt ttagtatgtg accttgcgtc tgcctcgcac ctaaaaagac
    17041 gagataatgt cataaccacc gtctatctac tgaccccaaa aagttggaca atttagtttt
    17101 aagcaaggga tttagttctg tattgcacag gactaagcaa ggccatcagc ttgtaaacag
    17161 acgcttagcg gcggttcaca ctcttcatca cacgccgaat gtcacgatcc tgctcgcgtc
    17221 gcttgatcga ttcacgcttg tcataatcat gctttccttt ggcaaggccg attaacacct
    17281 tggcaaagcc atccttaaga taaaccttta gaggaataag ggtcattcct gtgcccttta
    17341 gctcatctgc taggtgctga atctcacgct ttttgagcaa taatttgcgc gtgcgctccg
    17401 gatcagcatt ccagatattt ccctgctcaa agggagcaat atgaacattg accaaccagg
    17461 cctcaccatt cttgatttgg gcaaagccgt ccttgagctg gatacgcgcg gcacgaacac
    17521 tcttaatctc cgtaccggtc aacacaattc cagcctcaac tgtctcaacg atatgatagt
    17581 catgacgagc ctttttgtgt tgcgctaata cattaccttc accttttgcc atgcttaact
    17641 ccttttacga cctttctttt tagcagcttt ttggtaaaat ggtttctttg ctttttttct
    17701 tgtcttctgc tttgattttg gctttgaggg cttggactcc ttactcctgc tagcccttga
    17761 agcagccttt tgcctgtgct tatgcttagc tttagctgac cttgtggtct tttcaaccac
    17821 atcatagtca ctagccaagt aatcaaaatc aatgtcacct gtttccttgt cagccctcac
    17881 caatctaacc cgaatcggct gacctgctct aaataccttt cctgagcgtt caccctttaa
    17941 ggagagtgtc cgttcattat agtgataata ttcaggcaaa ttggtaatat gcaccagacc
    18001 ttcaattgta tttggcaatt cgacaaacat gccaaactta accacactag caatcacgcc
    18061 atcaaacaca tcaccaatat aatctgccat gtattctgct tttttcatcg cctcaaccac
    18121 acgctccgcg tcaattgcac gacgctctag ctgagatgac gatactgcca attctggaat
    18181 aacctgtgca aaatgatcca ccttctcctg cgtgatctga ttgtattctc gaatcatgcg
    18241 gtgcaccagt aaatcagggt aacgacgaat cgggctggta aaatgcgtgt agtagtctgc
    18301 tgctaagcca tagtgaccat gattatgctc agaataccta gcctgctgca tagagcgcag
    18361 cagcatcata ttcaaaacct ctgctccagg acttccttct acctttgcca taaaggcctg
    18421 caaggcttct tgagaaatct tattagcagt tccctgaatc tgaatcccaa aggcactagc
    18481 gtaatcaata aaggtctgca atttctctgc ctttggctcc tcatgaaccc ggtaaataaa
    18541 tggcaagcca gcccttgaaa aatgctcagc aacacattca tttgccgcta gcataaagga
    18601 ctcaatcatg cgctctgcaa cacctcgctg gcgcaagacc acatcaaccg gcatgccctt
    18661 atcattgaca ataatcctag cctcctgcgt gtcaaagttc aaggccccgc gcttcacacg
    18721 catcgcctct aagatctgat gcagctcaac catagtactc acatcatcag caattctatc
    18781 aaattcccta agcgcctcac tgtcacctgc aatcatctga ttgaccgcgc tgtaggtcat
    18841 tctaaaggtt gtgttaatca ctgactgaca cagctgataa tcaaccacat gtccctgatg
    18901 atcaatctcc atgatcgctg actgggtcaa ccggtcaacc tttggattga gagagcagat
    18961 accatttgac aaccgctccg gcagcattgg caccacacga tctgtcacgt aaacagaggt
    19021 cccgcgcgca gctgcctcac gatccaaggc tgacccttcc gtcacatagt aggacacatc
    19081 tgcgatatga accccaagct caacgtttcc attggccaat ctcttgatat ggatggcgtc
    19141 atctaggtct ttagcatcag caccatcaat agtgatggtc gtttctttgc gcaaatcaac
    19201 acgccccata agatcctgat cactcggagc atctggaatg gcattggcct cagctagaac
    19261 gtcatctgga aacgccgata caatatccat agattccaaa acctccagca catcaatgcc
    19321 gacatcatgc tgatgcccaa taatatcaca cacagtccct acaaaataat cctgcccagc
    19381 cttagggtat tgcacaatat cagccttaat gatttcagta ccatctaagg caattggaga
    19441 ttttgcgata taaatcctct gttgaatcct ttgatttttc gacttgatgt agccagcata
    19501 cttagggtga tcatcatcta aaataaccct accaacaacc gtctttaaag agcgctccac
    19561 gatagctacc acgcgagcct ctgctgctgt agccttaagc cgattagctg gttttttaat
    19621 aacagcctca accctatcgc catcactagc ataccccaca tcatcacgac caataaaaat
    19681 gtcgtcctca ttgtcatcaa ccgacaaaaa gccaaagcca gccttattgg cacgaaaaat
    19741 accttgaacc cttatctctg gctttttttg ctgtggtgct ctaagaaaca cctcaccctc
    19801 atctgaaaaa gacaaaagtc ccttgccttc cattttggaa atggctttaa tcaggcgagg
    19861 aaagctcctc gcatcagtca tctctagtgc agccgccaaa tcatgaatat ttgattggcc
    19921 atgctccttt aaataattcg taatgttctc tatcatcata cctatcttct atttctaaca
    19981 ccatacttga tggttgtgct cattgataaa aaaatgagct agactaactc tgtcaagctc
    20041 actccttatt tacttgataa aatggcaagc actaacgcaa ttcctaacca aaaaaacact
    20101 agaactgctg taaaacgttg cataaaagct tcaaatccgc gagcttttgt acgctcaaac
    20161 aaggcttctg agccactgct atcaaaaaca ttgctactag gatttttttg tggctgcata
    20221 aagatagcaa tcacaagcaa cactgataat actagcaata tcgtaagtag taagtcgtac
    20281 atgttaattc ctccactgta gtctcaatca ttctaacaca aaaccaacta agattcaaca
    20341 tgcagcgtta cttttctctc cttaggacag tatttaggaa ccttaatctt ctcagggtga
    20401 cttgttttat ttttactagt caaataattt ttgctgccgc aatggctgca ctccaaatga
    20461 atctttactc tcacatcatt tccctaatct tactatattt tatcagcgtc ataaggcttc
    20521 aaatcacccg cagcttcttt attaaagata tctctagtta ttatagcata ttatccagta
    20581 agaaaacaaa ctcaggactt ttagcaaaaa aggcttaagc gccaaccaat aaacattcca
    20641 aggctatcgg ggaatatttt ctaatggtta ttataaatca tgaacaatta cctaacaaag
    20701 caactccaaa acaaagataa aagacgaaca ttcaccttgc tgctcagcta tcaagataaa
    20761 caatcctgat agcatcaatt ttctttaggt cctcagcaat cggttgtaat atcagacaat
    20821 tcaggtgttg attaaaaaaa acgaaactac ggagaccaat tgtcagaaag ctattcacag
    20881 cccgcaggcg tcgtgctaaa gtattgtctg gaaaaagaaa ggtttaggaa tgattatacc
    20941 taaactcaaa ggagagaaac aatgagaaaa acaatgaaga agatgctagc agcctcgacg
    21001 ctctgcatca tcatgtcagg cagcttcatc agcggctcag ctagagtgtt ggcggagaag
    21061 tattatggtt ttaatgatgg cacaggagag cattcaccat tccctgtata cgttactcca
    21121 attactaaac ctaataggaa tactgccaaa gttgtctact gtttcaataa agatatgaag
    21181 tggccagaaa cttgggataa agcagcacca aaaaaaccag ataatttacc tctatactac
    21241 gatatggaag gtactgatca attattcagt acatatgcaa gtggacaact tactcctaat
    21301 gtcagtaaag tcttagctaa tataatggct aaaggttatc caaacaacaa tgagtttgct
    21361 caccatttta aactcactcc caattccgct gtaaaagtta ctcaaatcgc agtttggact
    21421 gttacggata acctaaaaaa ctattctcaa tacagtctaa ccagagaaga ggaagctgca
    21481 ttaaattacc taactgacaa aaatggggac gactttagcg atagtatcaa gttaaaatta
    21541 tacattccac aaaatcctcg aactataaaa tatcaaaatc ttctaggtta tgacctaata
    21601 gttaaaactc cagaaaaaaa agataattgt aaatgcacca aaatttatat agaagataat
    21661 ggaaaagatg gctattatct gtatatttat tatgacaaca atgaaaataa tagatatgac
    21721 tcggacaaag atagcctatt gcaaaagaaa tacataaaaa atgggaaaga tgggaaacca
    21781 ggaagaccag gggttccagg acttcctggc cctgctggac ctcaagggcc tagaggagac
    21841 aaaggagaaa ccggggaacg tggacctaaa ggtgaaaaag gtctagacgg taagcctggt
    21901 gaaaagggtc ctaaaggcga tacaggaaaa gatggtaagg acggacaacc cggacctcag
    21961 ggacctaagg gtgaccctgg acgtgatgga aaagatggcg aacctggaaa acctggcgag
    22021 cgcggtgaga aaggacctca aggcgaacgt ggacctcaag gacttcctgg gcccaaaggt
    22081 gagcctggaa ttccagggcc taaggatgaa gatggaaaag atggtgctcc tggacatgac
    22141 ggacaaccgg ggcctaaagg tgaaaaaggg gaccctgggc aacaaggcat tccaggacct
    22201 aaaggggaac ctggacgtga tggtaaagat ggagaaaaag gcgagcgtgg agagcaagga
    22261 cctcaaggcg aacgtggaga gcaaggacct caaggcgaac gtggagagca aggacctcaa
    22321 ggcgaacgcg gggagcaagg acctcaaggc gaacgtgggg agcaaggacc tcaaggcgaa
    22381 cgcggagagc aaggacctca aggcgaacgc ggagagcaag gacctcaagg cgaacgtgga
    22441 gagcaaggac ctcaaggcga acgtggggag caaggacctc gtggagaaaa tcctactcct
    22501 accccagatc caatgccaca accagaacca caaccagaac cacaaccaat gcctgatcca
    22561 gcacctaaac cagaatccaa gccagaacct aagccgatac ctcaaccaga ggttaagcct
    22621 cagccagaga caaaacctca acaaccaaac aagccatcaa ccattactag ccaatctagc
    22681 ggcaaatcac tgccaaaaac aaatgacact ggcagcttga tcacagcatt tggtacaggc
    22741 ttactcactc ttcttggact aggcttccta gcaaaacgca aaagaaagca ataattaaaa
    22801 cactacccat agccttttaa tcattggcta tcaactagat aacaaaaagc ttatcgtttt
    22861 actcctaacg ataggctttt tcgcattccc tattgcttgg tctcaatact atttttccag
    22921 ctttaggctg gttttgctaa tccaaaataa tatcagacaa tttccgtttt aattaaaaaa
    22981 aaaaaaacga aactacggac gccaattgtc agaaaatggt tcacagctta gagtcaccat
    23041 gttaagctat tctacgaaga agaaaggttt aggaatgact atttctaaac tcaaaggaga
    23101 gaaacatgag aaaaacaatg aagaagatgc tggcagcctc gacagtctgc atcatcatgt
    23161 caggtagctt tatcggcgga tcagccagaa tcctagccga gcagtattat gggtggaatg
    23221 atggaacaag agtaaaatca ccttttttcc tttatgttac gccaacaaat gaaacgacta
    23281 ggaaaaccgg aaaaaatggt acaatagtct attgtttcaa cagagataag gaatggccag
    23341 caaattggga agaaggaaga tccttagaac tagtgaatgc tgaaacagct tataaattac
    23401 ccatctataa taaattacta ggtacaactg attcctttac taaaaatgct agtaaaccaa
    23461 gagtatctgg agatattggt aaagcgctaa tagctgtact gaaaaatggt tatcctaata
    23521 aaaatttatc cggattagat gacactaaaa gtcgaatact aactcaacta gctatctggt
    23581 atttcagtga tagttataat aaagattatt ttaaacaaaa ttatgaatta actgatcaag
    23641 aaaataactc tcttatggag ctgattaaag tcggtgagga agcagctcaa aaacaagaaa
    23701 aaccagaata tcatttagat atatatataa ctacagaaaa aaattattaa cataaacctt
    23761 atcaaaacct gcttggttct actctaattc ctaaacttga ccctaagcct gaaccagaac
    23821 cagatcctaa gcctaagcca gatcctgaac caatgcctaa accagagcct aagcctgaac
    23881 cagagcctaa acctgaacct aagcctgaac caatgcctga tccggcacct aaaccagagc
    23941 ctaagcctga accaatgcct aaaccagagc ctaagccaga gacaaaacct caaaaaccaa
    24001 ccaagccgtc aaacgctact agccaatcta gtggcaaagc actaccaaaa acaaatgaca
    24061 ctggcagctt gatgactgca cttggtacag gcttactctc tcttcttgga ctaggcttcc
    24121 tggcaaaacg caaaagaaag caataagctg aataagctaa tgcaagacag cactagtata
    24181 taatgcgtgc atggtccatc taatgcagca caaaagcctt atcgcaccac gaatgggtac
    24241 gataaggctt tttgcatacg ctatagaagc tccaaaacca ctagactagg gcaacagcat
    24301 ggcaaggctt acgcctctaa atcatgcaga gccttactaa tctgtgtctc taaagcctga
    24361 aaatcaccag tattatcaat cactaaatca gcataagctc ttttctgaga catcggcagc
    24421 tggctagcaa tccgctgcct agcagctagc tctgtcaatt gattacgctt catcaggcgc
    24481 ttgagctgag tctcctcatc aacatagagc agccaaatag cgtcaaacca atcctgatag
    24541 cccagctcaa ctaaaagcgg taaatccata aagaaaatag cctctgtttg agatagctcc
    24601 tctttttgct tggctaaggc ttccctaatg atagcattct gctgctggga agatttcgcc
    24661 atattttccg aatgagcaaa cagcagctcc gctagcttag gtctgtctaa ttgccccgat
    24721 ggcaataaaa tatcctgtcc aaaggtctct agtaggacct gataaagctt gccgcccttt
    24781 ttttgcagct catgcaccac ctgatccgca tcaatcacct ggtagcctgc ttgtctgata
    24841 agtgcgacag ccgttgattt tccggaggca atacctcctg taatgccaat tacctttgtc
    24901 attgcttctg acacctagga cagacatgtg tccctcttcc tccaaccttg agctttacaa
    24961 tggaggtccc gcagcgctga cagggcttgc ctgtttggcc atagaccatc aaataatgct
    25021 gcatactacc attcattcct aaggtattct gataggttct aaccgtcgag ccaccctttt
    25081 caatacctaa ttgtaaaata cgaatcgttt catcatgaat ccgtttgatt tctgcctttt
    25141 tcaggctagc agatcgacgc tcagggtgta ctctagctgc ccatagcacc tcgtccacat
    25201 agatatttcc aagaccagcc actaaagtct gatccaaaag atgaggctta atggtctttt
    25261 tagaggctag cagagcagcc tcaaaggtct tcaattgaaa ggtctgcttc gtcggctcag
    25321 gaccaagctg acgcttctgg aaaaaagcag ccagctcagc ctttggtagc aaatcaaagg
    25381 ttccaaactt tctcacatct tggtaaacca gcgtggagcc atcagtcatt gtcaaaaaga
    25441 catgaaaatg cttatgctca ggtaccgtat caggaaacaa gaggtatttc ccctccatac
    25501 gcaaatgcga gatcataacc agctggccaa agtcaaagag caggtacttc ccgcgacgat
    25561 ctaccccttg cacctgctgc ccagggatcg tcatcacaaa atgctcaagg tctgttttga
    25621 ccatcttggg caccctaact gtcactgctg caatctgctt gccaacgact aagcgctcaa
    25681 gcccgcgtcg cactgtctca acctcaggga gttcaggcat aattaaagat accaaacgcg
    25741 ctaacaaaga aaccacataa ccaaaaccag cagaaccagc cagttttagc actctttact
    25801 cagtctcaat gttacaaaca cgcttccttt ctataagcta ctattagaaa gccccaccca
    25861 aaacctcaat aagcttgagc acaaaggact atcctttgat aagaactgtt atcattctta
    25921 ttttacgcat aatccataaa gaaagcaact ctcacgaaca gcctttgcag tcactgccgc
    25981 tatagcatca gaaaagcaca tctcgcccgc caatccagca agcaaagaca aagcccctga
    26041 gctagcctat tgtttgccag cccaagggca cgttgtggcc tttagtgtct gtaaatagaa
    26101 aaccaagcaa tgctgcaagc ctcaactgac aatgctaggt ctgatcagtc ctgtcatcag
    26161 cttgcggata atctatacta attggcctat caacaagacg gatactatcc tggtaaacac
    26221 cttctgtttc aaaaataaca atgtcattta atcccttgtt gaaatagccc tttggaatat
    26281 aaagggttaa taagggaccc acttcccaaa aacgaccaat agggtgattg ttgataaaga
    26341 cacaaccctt cccaaagcca gtcatatcaa tatagcttgc ctcaggctca tgacattcaa
    26401 attgataatg ataaaagccg ggctgcccct cgtaaaaatc gccatcaaaa caaagctgag
    26461 acaaatcatc aagcggcaga caatacatct cccaattggt cacaaagtgc aagtcagcca
    26521 tcataccacg tcctagaccc ttactttgac taggtgctgt cagcttgtgc ccataattga
    26581 cccggcccat attttcaatt aaaacatcga cctgactcaa ggcatgctgc tggttaatga
    26641 tgatatcatc accaatcgtc tcctgatact gtgttgcaac cttttgacca tctaaaaaga
    26701 cctgtgctct atctctacta tcaatcaagc gtaaacgctc gtcctcacgc ttatccttca
    26761 aaagatgtgt ccgatacagg atatagcccg ttgattgccc taaagcctct atgttactag
    26821 gatagcaagc agtctgacag ctgctgatgt gctccagcgt gctaaacaga ctaaccttgt
    26881 ccttcagacc aatcagaggc agtgacatca agggcttaat caagggagga gtaacctcta
    26941 tctctgaaag ctccgcggtc agacgctttt gaatcgcgta aaacttagct gtcggattgc
    27001 cagcctcatc taggatagcg tcataatcat aggaggtcac ctgcggaagg tccaattgct
    27061 ttctggcaga gcagccattc ataaacccaa agtttgttcc cccatgaaac atatacaggt
    27121 taatactgcc ctgcgccaaa acctccatca ctgcgtcagc tcgctcttca gggtcgcgtt
    27181 tgatgatggg ctcatgccaa cgattgaacc agccgtccca aaattccata cacattaaag
    27241 gccaatgctt gccatgctca gaaaagaagg cctgcatgtc agcaaaattc tcctgtgccc
    27301 ttgagccaaa gttgccagtc acaaagacat catcttcaat cagactacca gctctaagag
    27361 tggctcgcca aggaccatct gctgtaaaca agggcgcact gaggtgctcc tccataaagc
    27421 ccttaacagc tgttaaatag gccttatcct ctccatagga gccatattca ttttcaagct
    27481 gaaacatcaa aatattgccg ccctgctgcc attcatgcct tgctagtctc ggcagcagct
    27541 cctcataata gcgcctcaca taggctaaat agacaggatc agacgacctg atatgacaat
    27601 tctttgtcag cagccaagca ggtaggccac caaattccca ttctgcacaa atataaggac
    27661 taggtctgac aatagcatag agccccaatt gctgcgccag cgtcaaaaag gcttccacat
    27721 ctaattggcc agagaaatca tagctttcct ccctagcctc atgtaaattc caagggacat
    27781 aggtctcaac cgtattaaat cccagtgcct ttaaattata aagcgaatga taccaatcat
    27841 ctgggtgaat tctaaaataa tggatagccc ctgacaggat ttgcagcgat ctaccatcta
    27901 aataaaactg atctgaaatc tgaaaacgtt ccaagcttaa ttcctcactt attattgcta
    27961 ttagcctact aggcctcatt gctgagcggc ttggaatggc ccattctagc aacagcgaac
    28021 aggccattca gcagacaggc taacttatct tatggtaaca attgtaaaca ctatctacag
    28081 tctgactcct catgctatgc tgtcacagca gcaggataag agacagtgta tgccttgtca
    28141 tctgtcaatc taatcccata tttggtttca acaatagtat ggtcaaactg cggtaaaaca
    28201 gttatcggtc cttcaggcat actctccaga gacaattcaa atatcgctgt gtctgtgcca
    28261 tctcctgaaa catagctggc aagcttatct acgccattta cagtaactgc taactgacga
    28321 tcaccaagaa taaacatcgg ttgattaaag gtcatctgaa tggttatgct tactttgcca
    28381 ttttgctttg gagctgctga cgttattgtt acttcttcaa tttcagcctt atcctcacga
    28441 aactggtctg agatcatctg cttgatatta aaggttgaat aggtgatctg accactatat
    28501 tcgtataaca aaccaaccct ctcgtcgtct agttgaacca agctagagta agcaaaacgc
    28561 tttggctcaa aaatggttga agcgacccaa tgaatgctat cgtcctctaa gacctcaccg
    28621 acacgcagaa tccctttcat gcgctgattt ctaatcgtca gttgctcacc tgagggctct
    28681 cctaaaggat tggataaaac aacatattct ttgccatcaa ccatcatatg aatagctgac
    28741 aaattgacat aaggctctgg gaggtctgtg attgtaggat tatcgtccca agtcatacca
    28801 tagtctgtgc ttctggcaat aacgattgtc tttccggtat tgcgcataaa ctgtaataag
    28861 tgaccattgt ttagctgaat gatttgattt tctgtcaatt ctgtgactga tgtatcaaaa
    28921 tccttagagg ttgtttgttg gttatgacca taaattctgc catcatttgg tgattcacct
    28981 cgttgccatg tttgaccgcc atcatcacta aaaatattag cactgctttg acgacctaga
    29041 ctagctgatg tcgcattttg ttgattggta tagtaaatcg ggaaaactaa ccgtttcacc
    29101 tgctcaccct ctgcattgac tgcgtctatt tcaatgccag ctgcggcacc cgtacctaaa
    29161 aatcccatcc agtcttcttt tatttgtggg gtaatatcaa gaggtgtgga ccaggtttgc
    29221 ccttcgtctt cactggttag cagccataaa aagctggtca tgtaagtaaa tagaggagct
    29281 gtttgtgagc cttctctagt gatgccttgc ttagtgcgac cacttctcag ataaatattc
    29341 cctagtagaa tatcctctcc tgcctctgtt tgatagaggt tgccgcgtgt gctaaaggct
    29401 gtctcaaaat tgccctcatc aacatacata tctgtctgat ggccactctg gtcatagacg
    29461 ataccacctt cacgcacagt gtatttatta ttgtcaaaat cataaagatt taaataatac
    29521 tgaccgttaa tcaattcata tcctgagcct gctttagaag caacagcacc ctgtgactca
    29581 ggaaagacat ctaccagcaa ataaagcttg ccagaagcgt ctgttagcaa ggtggagtct
    29641 attgaaaaag cagattgagt catgttggta ttccaatcag ccaagctata ttgtgttgta
    29701 aaataaggct gagttggcat atctaagacc gtaatgttat tactccaggt tttgccatca
    29761 tcatggctta tcctgacaac agttgcaaca tctccccagt cattgtagtg cttctttctt
    29821 gcatctgctg cggctatcaa ggttcctgat ggcgttttga caacagaggg aatccgatat
    29881 tcaaagaccc cttcatcata tttgtcccaa acattcgtct tttcaccagt aactggtcga
    29941 agggttggct gatgagcctt ggcaatatct gtcagatcat acacatctgt atcaatcagc
    30001 acctgatcaa ccagtccctt taacccccag tgaaggaccg actcaccatc ataggtgcgt
    30061 ttcaagcctc caattgttag cgtatcagca gaagccttcc aaggtaattg cttcataaac
    30121 ccagcaaagt cagcttcccc atataagtca ccattcaagt aaatctttag cctagaccct
    30181 gtaaagacat agctgatcgt ctgccagtcc gagttcgtta ataaattaaa gcctgagcca
    30241 acttttacaa tcggaacctc agctccttta aattcaagac ctattttatt gtttttaggc
    30301 tcgataaaga aagaggcgta ttcattagct gatgcttgat ttgagatcga taacaaggcc
    30361 aagggcgatg agcttctcac tgttgtatca gcagtatcta gacggtatct gattgttaca
    30421 gttccttggg ttaggttcat cacatcgtct agcttaccaa gagcctcgtc atctgttacg
    30481 gctgcttttt ctgctgttgc gtccaaaata gcattgccta aatcaactaa aatggatgct
    30541 tgatctgaga ttggctgatc tgagatatag cttgcttcta tgcttgtata aacagctcgt
    30601 ccgccttctg tggtgtattt gatctgataa tgctctgcac ttcccaagat ctcctctggc
    30661 gtaacccatt gccaattggc tggcagggct actgtagata agggttctcc cttcttacca
    30721 atcagacctt ctttaggtaa tacagttaaa atagctactt ctcttgcaat cttagcagtt
    30781 ggtgttactg ttgagcctaa atcagcattg taaggaacag cactatagta aatgttataa
    30841 ataccaggag ctagctcaga caaggctgac aaatcatctc gaccagcagc ctgtaaagca
    30901 gcattggtat ttccaccctt gttagtaaac aagtattcat tttcaactga aaaatcaacc
    30961 acatagcctt cctgatcagt ggttacagct tgagctaaat caggactggt tccctctagc
    31021 atggtcaaat ccttgacccc cttgagaact ggctgtgagg cataataagc ttctgaggct
    31081 gctttttgct cagcatcttg gtaataacgc acataatcaa tcacaaaggc cgtctcatct
    31141 gaagctagat agtagcctgc atttttactc caattgcctc cagtagcaag gttaaactga
    31201 aggtattgag gcttattaaa ggcagctgcg gcagcctcta agcgatcatc accggttaaa
    31261 tacatggtat tataaacaat cccatcaaca taccattcaa tcttatccgg ataccaatta
    31321 ataccaaaga tatggtagtc atcataaaag tcatcactta atgtcagatt gccacccaat
    31381 gctgttgggc tatagcttcc atctttgtct gcatcaccct tgatatagta aaaatgaggg
    31441 gtcccgtaaa ctgttttgtt gctttgatca ccttcggcaa gctcaccctc atgctctccg
    31501 ttaggagcac cgattagctc cataatgtca agctcacctg tgcttggcca gccatagcct
    31561 tgagttgacg caatatcacc atctaaggta aaatcagccc ccaatgtcca aaaggctgga
    31621 aaggctccct tacccttggg aagcttggcc ctagcttcga tacgaccata taaaaattct
    31681 tgcttgccaa ccgttcgtac gcttcctgaa tcataaatga cctgacgtgc gcttgttcct
    31741 cctctaggat tggcataacg gtcctcccca taacgctctg tgacgtttaa aacaagattg
    31801 ccattatcaa gatagacatt ctctgtgctg tctgtgtagt gctgctgctc attcccgcga
    31861 atacttccca attcatatcc ccagttctct tggtttaacc gatctcctga aaactcatcc
    31921 tgccaaatca attcataatc attttcctct acgacactca cgttatcaat actagcagag
    31981 gcagccaagg cttccggaga agaggcttcc aaccatttga ctaagccaac aaaggtttct
    32041 gaagtcgttg ctgtaaagga gagcttgata tgtgaccaag taccgtctgt atctgtgagg
    32101 ctgacctctt tgataacagg gccctgaaga ttgtgattgg actctttagc ggtaaggtat
    32161 aagccattat gaggtgtgtc agcttcaacc ttcacatcag cctctagcgt ataggttttc
    32221 ccaaccgttg tagacacctt ttgaaggata tgctcatcta aagtgccgct tgttacctca
    32281 gcatagctat taccattctc tgttgtgagg actgaatgac ctccctctct atattgccac
    32341 tgattcttat tggacacata atcattgtca aaaccaccat tagccacctt attgagctca
    32401 atcggagcgt tagacttctc ttcgtctgct gtctgatcag cagcattgct ggtcacagca
    32461 ttagctacta ctgcctcatc tactgtcgtc tcctctgaga ctactaaggc ctcgctatct
    32521 gtatctgtag cttgaggctc ctgctcatgg cttatctctg ttactgctgc tttcgtaggc
    32581 tgctgcaggc ttacctctga aacgtcatca gcataaacag ccactggcag accagcagca
    32641 agaccaatac ccacacacac tgaagcaaca ccgacactaa gctttttgat ggcatatttt
    32701 ctaatttgct cttttccgat aggattaaat aacatgttta tttcctcact tatatataca
    32761 tcatttttaa acacaatagc ttttcaaagg cccatttagc ctaatccagt gctggtcagg
    32821 ctaacgacct tgttataaaa acgctttcaa ttcagcgctt aaaagaagat ataccagatg
    32881 aaaccgatat atcctctcac aaagtgacta acctgccttt tcaagctcat tatcagccat
    32941 cttaacaaat ggaaggtaaa tcaggtttgc caaggccaaa ttgacaagcg atagcacaat
    33001 agcacgccaa tcaaaaccag ttgaaaagaa gccatacaag acaggcggca ttacccaggt
    33061 cacattttgc gtaacgggtg caaccaagcc cagactagtt gcgatataag caacacttga
    33121 cataacagca ggacaaacaa taaacggaat aaacaacaaa ggatttaaaa cagttggtaa
    33181 accatacatc actggctctc ctatattaaa caatacagga gcaacaccta gcttagccac
    33241 ctcacgatag tgttcatttt tagacttcca gaaaatagca atcaagagcc ctaaggttgc
    33301 ataccataca aagaacactc gtccaaagat aaggaatcgc ctcatgcttt tgataagcct
    33361 ccaaattagc caagagggca acaccaaata ctccctccat atttggcgcc ataacattgc
    33421 cgccatgaat cccaaagaac cagaaaaatt gggtcaaaac agctaccaaa acaacagcaa
    33481 taaagctttg tgataagccc aaaagtggga tttgcaagac cttatagatc caatcaatca
    33541 tcaaagaacc cgttagcttt tcaaagacaa atgttaaaat agctacgcta tacaaggcgc
    33601 aaaagcctgg tatgatagat aagaagggct tggctacagc aggtggcaca ctatctggta
    33661 atttaattgt ccaatttttt aacattaatt tacaaaaaat aatagaggct aaaaagccaa
    33721 tcataattgc tgtaaaataa ccattggagt taatttgcgc accaggcaat aggcctgaga
    33781 tggtcacatt aagtgagctg ccgctgacag taacaccact gtccttaaaa gtcgtcacaa
    33841 gatcaacacc cttgagacct gacgcgtcaa tgctagaggt aacagaatcc ccaatcgcaa
    33901 tcacaaaggc agctaaagaa accaaacctg atgagagcgt atctgtctta taaagtttag
    33961 cgacattaac ccctaagcaa tacacaaata gcaaggacac aatcgaaatg cttcccttaa
    34021 agacaaggtt gttgatggtt acccaccatt ggaaggcctc tgtaatgcct tgcaagccaa
    34081 attggtctgg aatatccact aaaaaggcat tgatcaacag ggcaatagag cctgtcatca
    34141 caaccggcat cgttgcaata aaagaatctc gcaaggccac taaaaatcgt tgattaccaa
    34201 tcttcgtagc aattggcagc agcttttgcg aaagaaagtt catatagtta ttcattcata
    34261 gctccttaaa acaatcataa aacagctaag atagagcagt aaaggctctc tctaacagct
    34321 tagccttcat ttttagtttg ctcgctcgcc tgccatcttc tttccacatt aataataaac
    34381 ggcaagtaaa gaagaatatc tagaataatt aaaacaagct gtaggactga ggcttgccag
    34441 ctgcccgttg ccaaaaatcc tgaaataaca ggcggcatgg tccaccccgg atcagcatag
    34501 gtgccaggta caatgccaga agcaaaggca aaataagcga caaacaaatt cataacaggt
    34561 gctagtacaa aaggaataac tgtcaataga tttaaaacaa ccggtaagcc aaacatggtc
    34621 ggctcgttaa tgttgaaaaa ccctggaatc aaggtcaatg gtgacaagac ctttgcctgc
    34681 tgactagcct tgcgacgacg tgctaaccag gctaaagcca acaccaagcc aatggttgca
    34741 ccagctccgc cgataaaaac aaagttatcc ataaagacag acgtaaagac atgcggcaat
    34801 tcctgaccag ccttatgagc tgccatattt tcagtcaagt tagataacca gatcggcttc
    34861 ataataggat tgtttaggac atttccacca tgcacaccac agaaccataa aaagccatta
    34921 agaagaacaa cgataaaatt accaaataag gtacttccca gcaagccaaa tggaactcct
    34981 agtacggact taacaatgtc atggacattt ggcaggctaa aatgatccaa gaaagcataa
    35041 acagcaagcc aaaacacaat aatcaccgct ccaggaataa tggcgctaaa gctttttgat
    35101 actgcaggcg gcacaccctc aggcatctta atccgaatat cctttttcat aaaccattga
    35161 taagcatagc catttaccaa tcccaaaaca atggcaacaa acaagccgcc tgatgaaagg
    35221 taagaaggcg caatacccgc tacctcaccc aaggctttac cagattcatt gacaaatgaa
    35281 acagtaaatg gggtcactgt taaaaaggca gagatattaa taatcccagc agaaatcccg
    35341 tctgccttat actgcttagc caagctataa gaaatcccaa aggccgcaac caaggcaatc
    35401 agattaaagc tcgaatctac tcccttccac agataggtag agacaccaat ctcaccaagc
    35461 caagcttccc aaccaggaat cggcaggcta gcaatcacca ttaaaaagga cccaatcaaa
    35521 atcaagggca tagcgtaggt gatcccatca cgaatagcaa taagaaagcg attgcttcct
    35581 aggcgaccag caactggaac aagcttttgc tggataaaat cttcaaattt agtcattgtt
    35641 acctccttgt gacgttaacc tttcataaat agatactagc tcccttgcca aatcaacaaa
    35701 ggtaatacta gtcatcaaat gatcctgacc atgaactaat agtaggctta ctggtgtagc
    35761 atttccccgt gcctcttgag ttagcatatc tgtttgtgca tgatgggcct gcaccaatgc
    35821 cttatcggcc tgctttagac tttcctgagc ttgattgagc tctccctttt tagcaaaagc
    35881 aatcgcctcc atcgcaagcg acttggcact accaccatgc atgatcaggc ccataatcgt
    35941 ctctagctgc ttatcttcca tgaccaccac ctatttcatc aaactttcag ctaaggcaat
    36001 aaccttatca ccattcatca taccgtaatc aaccattggc acaaccgcca ctggaatgtc
    36061 cttttctgcc aagctttctt gaaatgctga caattgataa gcaacctgtg gccctaataa
    36121 caccacatca acaggatggc ttagagcgta atcctctgcc tcagtcaatg gcaatgcaaa
    36181 aatatctgcc tcaagccccc gattgtcagc agccttttcc atctttgtca ctaatagact
    36241 ggtactcata cccgctgcac aggccaacat aatttgtttt ttactcatga tcttctcctt
    36301 tatcccaaat cctaacgtcg aatagagcgc gacattctca caatggtatg tctttttcct
    36361 cggatagcgt cactaagagc aaagatattt tccactggcg caatcccgct atagccagca
    36421 tctccgatat gatgaatatc gacaccacag attttattgc gaatagcaat gtctcgaacg
    36481 atcgtagtat ctgacccttc ctgactcgtt ccaatagctg acataactag agcatcgtga
    36541 gcatgcacct cctcaacaat agctctaagg tcaccctctg taaagccagg aactgtccca
    36601 acagcaggaa ctaaaatcac atcagcccca gcctcgataa accgccgaac agtttctaag
    36661 tcaatcaccg cttcattaga gccagcagca tgcatctttc cagcaataat caagcctgaa
    36721 aaatagtgct tggcctgttg aatagctctt tcaatctgat tattgctaac accagtacct
    36781 ggatttcctg tcaagcaaac aaagtcaaag cccaaggctt caatctcttg aaaggtctta
    36841 gctgtcgcct gtcgcccttc tactagctcc aagcgctttt cagtcatgtc aacgtccaaa
    36901 tcaattggtt ctaaattaac accaattgga cgccccacca gacgacgcag ctctaaaata
    36961 ggctgatcag tagcaggtag accagatatt tgaacatcaa agacatctac acaattcagc
    37021 aaaatcaaat cagcactaaa ggctgcggca acctcagcgt tcgtaaggtc atctccagtc
    37081 caagagggtc ttggcgctac attttctgag acaatggtac gtccctcgct tgccttaatg
    37141 gcttgcttta gctctaacga tgttaactgt agcatttctg agctactagc actcaataat
    37201 cgtgttttca tcgcttctcc tttattttta ttttaaaaac attaacaaaa gataaataag
    37261 atttaactct tatttgttta ctttttataa acaaataaag tatattctat ttaccaatat
    37321 ttgtcaacgt tttcaggcag gatttttaat tcttttttgg tatgatagag gtacgataat
    37381 agaggttact atgaagacgg ataaacaaca agagctttac gcaaaaattt tagataccat
    37441 ttatgcccaa cggcctattt cacgcattga tatttcaaag ctaacgcaca tcacacctgc
    37501 tacagtaggg gctatcacta aagagctgct agcacagggg tggatacacg aaatcggaga
    37561 gctgacggac cactccgttg gccgcaaaaa aatattactt gatgcttcgg ctaacgcctt
    37621 ttattttgct ggtgtcgaat tgtccgaaaa gcatttctat ttggtcatta cagataacct
    37681 gggcaccatc tatgccaagc acaaccaaca gatcgaccca agcatttcct cctactacaa
    37741 agcagactat atctctgagc tgattcaagc cttcctcaag cagcacaagc actatgatgt
    37801 acaagccata ggaatagcac tgcctgggca ttacgatcat tccacctcca gctcaacgca
    37861 tattaacacc aacaatccca tctggcagca ggtcgattta accgcaattg cgaagtcctt
    37921 ccctattcca gtggtcttta gcaacaatgc tcactgtatg attattgcca agcgcttata
    37981 cgagcgtcag gcacataatc acaattttat tttctttcat gtcggacgag gcatgcactg
    38041 ctcctatatg tataaggggg tcatttatag ccgtcacaat gctgttgttg gggaaatcgg
    38101 acataccatt gtcaacccca ctggagagct ttgtgaatgt ggcaaaaaag gctgtttaca
    38161 gacctatgcc agcaatgcct ggttgctcaa aaaagcaaaa ctgctacatc agtatgcccc
    38221 caattctcat ctaagaagcc ttgtcgataa ggcctgtgag ctcaagctag accatctctt
    38281 gattgcctat gagcttggtg atgtcggggt gaccacgctc attcacacag ctattgatta
    38341 ccttgtttta tccctgtcta acctctcctt actgattgat accgagcaaa tctatctcca
    38401 tggcagattt atcagccatc ctcttatatc ctccaaaatt ctgcaagccc tgcaaaatga
    38461 cattaagctt cttagcaatc aaaaaaagcc agaaatcatt gtcatgcctt tttctgtcta
    38521 taatgccgct gtgggagcta caggcttatg tatagatgag ctttacctca attataaaaa
    38581 caaatatgat tgataacccc cacaccaata tcagctaaag ctttaaagcc catttgagaa
    38641 gctatttctc aagtgggctt ttgcattatg cgactttcag tccatctcgc tccgcaggtg
    38701 cgagacaaat gataaccata aaaaaagaga ggcacttggt tctctctgtt ctatcctaat
    38761 gccccatttg aaactcacca gcaaaatact ctgccagcat cagtctatgc ttgtctgaga
    38821 ttgaagacag ctctgcaatc tcttctctag aaaaataacc gagccttaag gtttcatcat
    38881 tttgataatc agtgatagcc ttatctgcct tggctataac ctcataaagc atcacaacgg
    38941 tctgaacctt atcaccattt ggataggtct cttcaaaatt ggtataaaca ttcaacaacc
    39001 gtaaaggctc tactgtaatc cccgtctcct cataaaattc acgcctgcag gtttcagcag
    39061 aagactcacc cagctccatg gcacctcccg gaattgccca ggttttctta tctgcacgta
    39121 gctgcaaaag caccttacct tcggcattgg ccaaaatacc accagcaaaa gtcagaataa
    39181 tgttatcatg ccccaccttt gagcgaatat aggaaatata gtcctgtgtc atcgtaactc
    39241 ccttcattgc catcataaga ttaaagccag tcagctggcg caattgctgc ttttttgcca
    39301 accaataagc aatgcaggct ttgtctcttg tccttgatag gctggcaaag catatagccc
    39361 taatttttca acctgattat atcacacttt ttaaaagcca gaaagagact cgaatgccaa
    39421 gtcccttttc tttcaatcta taaccaacct cagaaaaact cagacaagct acgataactt
    39481 ttttaatgtc ttctttggcc aatggtttgc gactggtcat tgaattactt tcaatattat
    39541 ccccatcatc acatgataac cacaaataaa cacgtacttg tgtcattgcc ttctcctcaa
    39601 tcagtagtag gtacctactg tttttttgat tgattgtacc tataggtgtt tttttccttc
    39661 aaaatcttta aataaaatac cctttataa
//
LOCUS       DARYXZ010000016        39095 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYXZ010000016 DARYXZ010000000
VERSION     DARYXZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39095
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(93..464)
                     /locus_tag="TV186_000731"
     CDS             complement(93..464)
                     /locus_tag="TV186_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532144.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TV186_000732"
     CDS             683..1321
                     /locus_tag="TV186_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1532145.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TV186_000733"
     CDS             1517..2053
                     /locus_tag="TV186_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1532146.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TV186_000734"
     CDS             2916..3320
                     /locus_tag="TV186_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL1532147.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TV186_000735"
     CDS             complement(3376..4860)
                     /locus_tag="TV186_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL1532148.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TV186_000736"
     CDS             5219..6442
                     /locus_tag="TV186_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1532149.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TV186_000737"
     CDS             complement(6532..6891)
                     /locus_tag="TV186_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL1532150.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7769
                     /locus_tag="TV186_000738"
     CDS             7056..7769
                     /locus_tag="TV186_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1532151.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEALKA"
     gene            complement(7848..8675)
                     /locus_tag="TV186_000739"
     CDS             complement(7848..8675)
                     /locus_tag="TV186_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL1532152.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8936..9064
                     /locus_tag="TV186_000740"
     CDS             8936..9064
                     /locus_tag="TV186_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL1532153.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9118..10431
                     /gene="obgE"
                     /locus_tag="TV186_000741"
     CDS             9118..10431
                     /gene="obgE"
                     /locus_tag="TV186_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL1532154.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10552..10710
                     /locus_tag="TV186_000742"
     CDS             10552..10710
                     /locus_tag="TV186_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532155.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10763..11467)
                     /locus_tag="TV186_000743"
     CDS             complement(10763..11467)
                     /locus_tag="TV186_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL1532156.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11802..13202
                     /locus_tag="TV186_000744"
     CDS             11802..13202
                     /locus_tag="TV186_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1532157.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13212..14306
                     /locus_tag="TV186_000745"
     CDS             13212..14306
                     /locus_tag="TV186_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL1532158.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPREVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14412..16406
                     /locus_tag="TV186_000746"
     CDS             14412..16406
                     /locus_tag="TV186_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1532159.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16420..16737
                     /locus_tag="TV186_000747"
     CDS             16420..16737
                     /locus_tag="TV186_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1532160.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16734..17069
                     /locus_tag="TV186_000748"
     CDS             16734..17069
                     /locus_tag="TV186_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1532161.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17069..17503
                     /locus_tag="TV186_000749"
     CDS             17069..17503
                     /locus_tag="TV186_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL1532162.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17578..18957
                     /locus_tag="TV186_000750"
     CDS             17578..18957
                     /locus_tag="TV186_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1532163.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18954..19106
                     /locus_tag="TV186_000751"
     CDS             18954..19106
                     /locus_tag="TV186_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532164.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19263..20003)
                     /locus_tag="TV186_000752"
     CDS             complement(19263..20003)
                     /locus_tag="TV186_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1532165.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(20003..22168)
                     /locus_tag="TV186_000753"
     CDS             complement(20003..22168)
                     /locus_tag="TV186_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1532166.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22360..24351
                     /gene="uvrB"
                     /locus_tag="TV186_000754"
     CDS             22360..24351
                     /gene="uvrB"
                     /locus_tag="TV186_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL1532167.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24690..24833
                     /locus_tag="TV186_000755"
     CDS             24690..24833
                     /locus_tag="TV186_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL1532168.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24845..26383
                     /gene="dltA"
                     /locus_tag="TV186_000756"
     CDS             24845..26383
                     /gene="dltA"
                     /locus_tag="TV186_000756"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL1532169.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26380..27627
                     /gene="dltB"
                     /locus_tag="TV186_000757"
     CDS             26380..27627
                     /gene="dltB"
                     /locus_tag="TV186_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL1532170.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27645..27884
                     /gene="dltC"
                     /locus_tag="TV186_000758"
     CDS             27645..27884
                     /gene="dltC"
                     /locus_tag="TV186_000758"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL1532171.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27877..29130
                     /gene="dltD"
                     /locus_tag="TV186_000759"
     CDS             27877..29130
                     /gene="dltD"
                     /locus_tag="TV186_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL1532172.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29164..30138
                     /locus_tag="TV186_000760"
     CDS             29164..30138
                     /locus_tag="TV186_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1532173.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30679..31938
                     /locus_tag="TV186_000761"
     CDS             30679..31938
                     /locus_tag="TV186_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1532174.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     DKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32111..33811
                     /locus_tag="TV186_000762"
     CDS             32111..33811
                     /locus_tag="TV186_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL1532175.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33840..35972
                     /locus_tag="TV186_000763"
     CDS             33840..35972
                     /locus_tag="TV186_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL1532176.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSIAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLAFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36048..37352
                     /locus_tag="TV186_000764"
     CDS             36048..37352
                     /locus_tag="TV186_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1532177.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37353..38213
                     /locus_tag="TV186_000765"
     CDS             37353..38213
                     /locus_tag="TV186_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1532178.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38238..39068
                     /locus_tag="TV186_000766"
     CDS             38238..39068
                     /locus_tag="TV186_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL1532179.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT        10877 a         7380 c         9049 g        11789 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggcctta aaagcctaag gctagactag tcactggctg ggttagctgc
     7801 tgaattgata gtaaaaaaga ccagtcttag actgatctgt agggtgatta gatcgcccat
     7861 tctcctcctc ggaagattgg aatgacttct ccgtctttgg taatgccatc gatatccatt
     7921 tgttcagaac caatcataaa gtccgcgtgg gctgttgagc gatttaggcc agccgcttcc
     7981 caaatgtgct gctcaggcat tccaagtctt aggtcagttc ctggtgccct gtagtgaagg
     8041 ctgtcaaact gataatcatt gaggagcctt gccttttttt ctaaacgttc ctgatgttgg
     8101 tcccaggcct tgacaggatc tgtctcgtaa atgcgattca ttttgaaaat ggcatcccac
     8161 aaagcgtcca cctgctcttc ttcgcttgtc aggtttggaa aaaccatagc agcccattcg
     8221 ggaccggctg cagctgctag attccagctg actttgttgg cctgagtggc agcccgctgt
     8281 ttttcaagag caatagctgt tgcgcgtgtt gctccagcta gcctatcaga atcaatatca
     8341 gcaaagacgt ttggattggc agagcgaatg actaagcggc ttgctttttg atcaaggaga
     8401 taatgtgact gttcaacgac ataatctggt acctgcaaga gacggtcttc atcagcctta
     8461 agaagcttct cgcgtgtgat ctgatcgtca ttatagtcaa caagaacctc agctgcacca
     8521 gcctcatagg cttttttggt taatagccgc gcaagcttgt gttgctctac tgcaatagaa
     8581 atgagtagtg tgtgaccttt ttgaatgttg actccttttt tgataagaag gttagcgtat
     8641 ttttcaagat aatcgtcaaa atgtggcaaa accatagcag tctcctaata tgttaatgtt
     8701 gcaaaattta atgtatcata tttgcgacta tttcacaagg agctagcctg tttcataggc
     8761 taaatgtctc ctagaatgcc tatcgtaaaa ggctcagtgt tggttttctc tgatgagtta
     8821 aaaaacgatc ccttttttga tcagtttgcg ctgcccttgc taatagatat ttgcttaata
     8881 gcgacattcg tgttaagata taagaggaaa aaatcaatag atgaggtatt taacagtggc
     8941 atttggagaa aatggacctc gcaaaaaaac tgcctttgaa aagttgacaa cagttgttgt
     9001 gatcgtgatg gttcttgtga ctgtcggtgg acttattgcg ggtgccctgt cagtattgat
     9061 gtaagaaaac gctgaaaggc gtttttttag gataagagaa ggtttgagaa gaaaagtatg
     9121 agtatgtttt tagatactgc taaggtcagt gttcaggctg gtcgtggcgg tgatggtatg
     9181 gtggcctttc gtcgtgaaaa atatgtgcct aatggcggcc cttggggcgg tgatggtggc
     9241 aagggtggct ctgtcatttt caaggttgat gaaggtttgc gtaccctaat agactttcgc
     9301 tacaatcgta agttcaaggc caaatccggt gaaaaaggca tgactaaggg catgcatggt
     9361 cgtggctcag aggatttgat tatctcagtg ccacagggaa cgactgtgcg tgatgctgaa
     9421 accggtaagg ttctgacgga tctggttgag catggtcaag aatttgtcgt ggctaagggt
     9481 ggtcgtggcg gtcgtgggaa cattcgtttt gcaacgccgc gcaatccagc acctgagatt
     9541 gctgaaaatg gtgaaccagg agaggagcgc caattagagc tagagcttaa gattttggca
     9601 gatgtgggac tggttggttt tccgtcagtt ggtaaatcaa cgctactaag cgtggtctca
     9661 tcagccaagc ccaagattgg tgcttatcac tttaccacta ttgtgcctaa tctaggtatg
     9721 gttcgaacca aatctggtga gagctttgct atggcagatc ttccaggctt aatcaaggga
     9781 gctagccagg gtgtggggct tggcactcag tttttgcgcc atattgagcg tacacgtgtg
     9841 attctacatg ttattgatat gtcagcagct gaaggacgag acccttatga ggactatgtg
     9901 gcgattaata aggagttaga agcatataat cttcgtctta tggagcgtcc gcaaattatc
     9961 gtcgccaata aaatggatat gccagaggca aaggagcagt tgcagcgctt caaggaacag
    10021 ttagctgctc agtatgatga ctttgaagaa ctgccaataa ttttcccgat ttctagcttg
    10081 gcacatcaag gcttggatag cctattagaa gcaacagcag agctattagc aaaaactgat
    10141 gatttcttgt tgtatgatga ggctgatttg gctgaggacg aggcttatta tggctttgcg
    10201 gctgaggaaa aggcctttga gattagtcgt gctgatgatg cagcttgggt attgtctggt
    10261 gagaaattag agcgtctctt tgtgatgacc aatctggagc gcgacgaatc tatcatgaaa
    10321 tttgctcgtc agctacgtgg catgggtgtt gatgaagcgc ttcgtgagcg tggtgctaag
    10381 gacggcgaca ttgttcgcat tggcaagttt gagtttgaat ttgtagacta atgacaaata
    10441 ccaagcttag ctgttttttg tagcaagtga tgctgagtca tatctgaagt aggctgtttg
    10501 ctcaattcac agcaatgagg tcttggttga tgtgagctag ggaggttttt tatgggagat
    10561 aaaccaatat ccttcaagga taaggacggt aactttgttt cggcagcaga tgtctggaat
    10621 gctgaaaaat tagaagaatt atttaatctc ttaaatccca ataggcgttt gcgtttggaa
    10681 cgtgacaaat taaaaaagga tgaagcttaa gtgcacttcc tctcaatcgt tagatttagt
    10741 gtctaacttt tgagggtgca cttcaaggct tcgtcctttt ttgatgcttt ttttcttggt
    10801 gatgctgcaa atgtagccaa ttaaaaaagg tgtaaatgtc attaacaaga aaggctgcaa
    10861 aacaaatgac cactgcgtat tggctggtat ttgcttgagc agcatagagc cacaggagaa
    10921 ttaagaccaa atcattaaga gcataggcca aggcaaaata agggctacgt ttgtagctta
    10981 agtaggctgc tgaaaaagag gtggcaatag ataaggtaga aacaggcaga taggctgtct
    11041 taagataggc taagatagca tagaacaagc tggtaactag tatggtaaga accactaagc
    11101 gcagccggtc tgctgttgtc aagcgtgaga tggttacctg agatgtctgg tcttcaaatg
    11161 ggtggcttag ccaggtaaac agtgacaaaa tagccatcgg cagggtcatg aagagatagg
    11221 ttatcagctc cccgtaataa ctgtttaata gtgacagata ggcataaata agggagaaaa
    11281 taatggccaa gctctgtcca atcggatttg ccttggcact aaagattaaa gctgtcacac
    11341 cgattaagga agctatcagt gctaagggag cttgttctcc aaagaaaaag gcactgagga
    11401 gaatagccga aatggaggtt aaccaaagcg tccactcggt ttttgtaaaa tagtttaaat
    11461 aagccatatc cttattcaag cataggcctt tttatctgtc aatagggtgt cgaccttagg
    11521 gaaaaataag ctaatacctg ccatagtgca attggttgtg aggcactaat actagcagat
    11581 aatggtgtta actagaggca aatgagctaa gagtttcctt attggctgct gctaatactc
    11641 cttgttgact ggtttagaag aaaaggacta agagccttag cttggctttg tcagttagtt
    11701 tccttgatga taaggaaaaa ctagattttt taaagcgttt acagtgtcct tttttcttcc
    11761 tataataggg gtataagtga caaaaagaaa ggaaaaagca tatgaagcaa tcaaaacgcc
    11821 gttaccaatt tccagaaggt tttttgtggg gaagctcaac atctggccct caaagtgagg
    11881 ggactgtttc tggagatggg aagggaccta gcaattggga ctactggttt agtctggagc
    11941 cagataagtt tcatcatcag attggtccag aggtaacctc aaccttttac accaactaca
    12001 aaagcgatat tgctctttta aaagagaccg gtcacacagc ttttcggacc tctattcaat
    12061 ggtctcgact gattccagaa ggggttggtc aggttaatcc aaaagctgta gccttttacc
    12121 gagaggtatt tcaggaaatc atggctcagg acattaagct gattgttaac ctctatcatt
    12181 ttgatctgcc ttatgccttg caaggaaaga gaggctggga ggctaaggag acggtctggg
    12241 cttatgagac ctatgctaag acctgttttg agctttttgg tgatttggtg gatacatgga
    12301 ttacctttaa cgaacctatt gttccagtcg aatgcggtta tttggggcat taccactatc
    12361 cttgcaaggt agatgccaag gcagctgttc aagtggctta ccatacccag ttggctagct
    12421 cacttgctat caaggcctgc cacgagttgt atcctaagca taggattagt attgtgctta
    12481 atgtgactcc tgcctatcct agaagtgatc agccagaaga tgtcaaggca gcgagaatcg
    12541 cagagctttt ccagactaaa tccttcctag atccgtctgt cttaggagtg tacccagaag
    12601 agttagtagt tcttttagag gcagctgatt tattgcccca gtatagtgct gatgaattgg
    12661 ctattatcaa aaacaatcct gttgatttct tgggagttaa ttactatcaa cctttgcgtg
    12721 tgcaagcgcc tagcaaaaca agacaagatg gtgaaccaat cacgctagcc tcttattttg
    12781 aaccttatga tatgccaggc aaaaaggtta accctcatcg cggttgggaa atctatgagc
    12841 agggccttta cgacattgct cttaatttaa aagagcatta tggcaatatt gactggttag
    12901 taactgaaaa tggtatggga gtagaaggtg aagaagcctt tttagttgat ggtcagatcc
    12961 aagacgatta ccggattgcc tttatcgaag accatttgat tcaattgcac agggctttag
    13021 aagaaggcgc gaactgtaaa ggctacctcc tgtggacctt tattgattgc tggtcttggt
    13081 taaatgccta taaaaatcgt tatggcttgg tagccttgga tttagagact caaaaacgaa
    13141 cccttaaaaa atctggccac tggtttaaga ccctgagtca gacaaatggt tttgataaat
    13201 aggagcgtat gatggtcacc ttaggatttt ccctttaccc tgagcggcat ggttttgcta
    13261 agagtaaggc ttatattgat ttactgcact gctatggagc caagcgcttg tttatgagcc
    13321 tcttacagtt ggcgccaaat gatcccaaga cctttaagtt ttatgcggat ctgattgctt
    13381 atgccaattg cttgggcatt cgggtcattg cagacgttag ccctgctttt atcaagcagg
    13441 ctggttggtc agatcaggtt attgaagagg ctcatgcttt tggcttagca ggcttgcgtt
    13501 tagatgaggc cttgccttta gaggatattg ttaggctaac gaaaaactct tttgggctta
    13561 agattgaact caatatgagt actgacaaga gtttattgac agccttgcta aaggcagctc
    13621 ctgatcggag taacctcatt ggttgtcata atttttaccc gcacgccttt accggcctgt
    13681 cactggagca ttttaaggaa atgtcccatt tttaccacga gcatgggatt gcaacggctg
    13741 cttttatcac agcccaatca gcaaaggaag gcccttggcc gctgtcagag ggcttaccga
    13801 ctgttgaggc tcatcggcaa ttgccaattg acgtgcaggt ggaactgatg aaggcgacag
    13861 gaactattga tactgtcatt ttgtccaatc aattcatcac tgaagatgaa ctcgttcagt
    13921 gccgtcaagc cttggataga tcagtcatgt ctattaaggt caagcctctg gttgatttga
    13981 cggacataga ggagaagatt atctgttacc cacattgtta tcggggagat gtatcagatt
    14041 atgtgattcg ctcaaccatg ccgcgtgagg tatatgctca agaagcaatt gctccaagag
    14101 agcagcccaa gcaggttaag cgaggcagta ttatcattga taatgaccgt tacaacaggt
    14161 acaagggaga attgcaaatt gcactcaaag cctttaccct tagctcaaag gccaatgtgg
    14221 tcgccaacat taaagaggat tacctaagcc tattagacga gttgaagccc tggcaggagt
    14281 tttcattggt gattgagact gactagtctg gcttcacaat cgatacggaa aatgatggtc
    14341 acttttttca ggaaacattt gctaaactaa gagagtaaag aaagcgtttt ctaaaagacg
    14401 aaggaggaat gatgctatca aaaaaagaaa tggctatagt agcatttcta atcagccaaa
    14461 aagggcagtt tgtctctagt gctaccttgg ctaaggctat tggcatgagt gatcgcacag
    14521 tcagaaaata cctaaaggag ctgattagca gccttcctag taagggagcg cacatcattt
    14581 ccaagcaagg tcagggctac tgtttagaga ttgatcattc tatggcgttt gagatctttt
    14641 ggcaggaaag cttggcctct aaaaagcgct tggctgatgt gactcaggtg gaagaaacag
    14701 ttgatcggga gcattatttg ctaaataaat tcttctttga agagcccgtt tgggattttg
    14761 aagagctctg ccaagaattg tatattagtc ggacgaccct aaaccatgtt ttagcggtta
    14821 ttagagaccg tattaggcct tatcagctac agcttgatgt gagtcatcag cgcgttcagg
    14881 tgacaggtaa ggaagaggct attaggcatt ttatcatgga ttattttttt gctaccagct
    14941 ttgatgactc catgtacgcc atagtagaca atacctttct tgatcatatc aagtttgctg
    15001 atatcacaat aattgtttta gatgaatgtc gagatgccaa actaaagctt tctgattttg
    15061 tcatgcacaa tttggttttg cacattgccc taatggttca gcgtattcgg tctggctatc
    15121 cgttagcatt tttttccatt ccagcagcta ttcgccaatc agacgagtat caagtggctc
    15181 tacgtatttt atatcgagta gaagaagtga tgggcattcg ttttcctaaa gaagaagcta
    15241 actatattgc tttacacctc aaggttaagc attccgttga tggcagccca caggacaata
    15301 aggccgatga cttgctgaga agtcatttaa aagcaggtat tgtcaaggct agtcagctga
    15361 caggtatgtc tttggaggct gatagcagct tgcttcaagg cctattggcc catatgaagc
    15421 ctttagccac aaggcttgaa aatcatattc agctgaccaa tcccttaact gaggagatta
    15481 aaagcaaata cccagaggct tttgccctga ctaagcaagc ttttgagaat attcctgagc
    15541 ttcaggctta tgacctgtct gatgacgaat gggcttacat tagcttgcat atcatggcag
    15601 ctattgagcg ctattccaat cgtcacaaac tgagggtgct tgtggtttgt gccacaggct
    15661 atggcagtgc catgatgctg aaaaatcgct tggaaaagga atttgaaggt cgctttcaga
    15721 ttgtagatgt tatcagctac tatgaaataa cacaggaacg actgcaaacg gttgatgtga
    15781 ttatttcttc tatcagcctt gctaatgtca tgtttttaac gccagtcatt actgtcagtg
    15841 tctttttatc tgatcaagac atcaaagcca ttcgccaatt tatcggggag caggagggaa
    15901 taagaagaga agctgcgtcg tcatcgcaga tgagcttgga aaaagcagag cagattctaa
    15961 aaggtgtctt tagtcctaag cgttttcttt atgtgaaaga aaaactatca aagaaggcct
    16021 tgctgttaaa gatgattgct tgtcttgacg aagcaatgga tgaagccttt gttgaggcct
    16081 tttatcacca aatcgtgttg agggaaaatt atagctcaat tgtttttggt gaggtgcttg
    16141 cctttccaca cccggctaat cccatgacct attctgaaca ggtggtggtg gctgtctgtc
    16201 aagagcctat tgactgggac gagagtcatc gggctgttca ctttatcttt ttgttgtcac
    16261 cgtccaaggg acgtaacagc tatttaaaat atatctcacc gagcttggtg tcttttgtca
    16321 atcaagcaga gcttcagcag gctttattag aagaaccaag ctatgcacaa ttcatcacat
    16381 tatttacccc actcatcact gaataaaagg agaagtatta tgaaaaccat tatgttagtt
    16441 tgtaatgccg gcatgtcaac cagtatgctg gtgactaaaa tgcaaaaagc cgctcaagcg
    16501 cgtggcatcg aggttgagat ttgggcagtt cctgtgagcg aagctgacaa tgaggttgct
    16561 gctaaaacca ttgatgtcct catgttaggg ccgcaggtca aattcttact aaaggacttt
    16621 aagaccaaat ttgaaccggc aattaaggta gatgtcatta acatggctga ctatggcctc
    16681 atgaatggtg acaaggtgct tgaaacagcc ctaacaatga tggaggaaga ggtatgacac
    16741 aatcatcaaa cctagaggcc attatgggat taatcatgta tggcggtgag gccaagggca
    16801 aggctgtaga agctattcat gcagctagag atggtcaatt tgaaaaggct cagcacttgc
    16861 ttcaagaggc tacacattct ttaaatgttg cccatagatc acaaaccaat ttgctatctc
    16921 aggaagcagc tggagatcag gttgatttgt ctttattgct ggtgcatggt caggatcata
    16981 tgatgacagc cttagccttt attgatttgg ccaaggaatt ggtcgctgtt tatgacaaaa
    17041 tatcaagaat ccaaagaggt gagctatgat gatgattaca gcagaaggag atgtctctgt
    17101 cactcaatgc ttcaaggcta tactaagctc tctccaagag gattatcatg aaaacaccct
    17161 gagacggctg ccaccagctg aattaaaagc agggctaagc tacataaagc attatggcaa
    17221 aagcaaggag cataacgtta gagtgctgat cacagcctta gaagctccgc acttatatgc
    17281 tgcttgcttt agctctaatc atgggctaaa aacattaagc taccgcttag aagctctggg
    17341 agagaagcgt accaaaataa cctattgcta cgactatcag ccacttgatg tctttcaaaa
    17401 agccaatcag ctgatcattg ggaagctttt taagaagagc ttcaaacggc aatcacaagc
    17461 ccaattggca gcccttatcc aatatgctaa gcagctaagc taggggaaga tttgagtaca
    17521 gattatctgg ctgattatag ggcttatcat actaaaaaat agaaacagga gaaaattatg
    17581 tcacattttt cggataagtt tatggagatt tcaggaaaga tgggatccca gcggcatttg
    17641 gttgccattc gtgattcctt tatttcgcta atgcccatca cgatggcggg ctctgttgcc
    17701 gtcttgctga atgttttctt gcgtgatatt ccaaacaata tgggctggac tggttttgca
    17761 gcagccatgc agcccattat tgacatcaat ggttatgtgt attttgggac aattggtatc
    17821 atggcactct tttttgcctt tgcttttggg tatcatttag ctcttatgca caaggtgaat
    17881 cctttggctg gaggtttaat ctcctttgct tcctttgtcg ccacccttcc tcaaagctta
    17941 accatttcca caccacttga aggggcgtca gcaagtttat tagcaggctt aaaggatatg
    18001 ggactatcag tggtcactgc aaatggagcc cgagttttag aaacaagcca gtggggagca
    18061 attgccctca aatatgctgg agcaacaggt ctttttacag cattgatcat tggcttttta
    18121 tctagctttg tttatgcgac tttgaccaaa cgtaacctga ccatcaaatt gccagataat
    18181 gtgccacctg cggttaataa ggcttttgcg gctattattc cagggacagt cgcgatttat
    18241 gtgtcagcga tcgtagctta ccttattttt gccctcacag gctcgtctct aagtgatatg
    18301 atttcgacct atatccaatt gcctttgttg gggctgtctc aagggcttgg ctctgttatc
    18361 ctgttaacct tcttggttca attgctctgg ttctttggtt tgcatggtca caatgtctta
    18421 gcacccgtgc ttgatggtgt gtacttagtg gctctaacag aaaatacagc tgcctataat
    18481 accagtcaga gcgttgctaa tctgccttat ctctggacga gaggctcctt tgatgcctat
    18541 gcacaaatgg gtggttcagg tgttactctg gctctgatta ttgctatctt tattttctca
    18601 aaacgtgagg agcacaagac cattgccaaa ttatcagcac cgatgggcgt gtttaacatc
    18661 aatgagccaa ttacctttgg tatgcctatt gtcttgaacc caacctttgc tatcccatgg
    18721 ctaatcgtac caccaatttg tgctagcatt gcttatgctg ccacagcaat aggcttgatc
    18781 cctcccgttt tcttgccagt tccttggatt acgccagttg gactttacgc ttacttggct
    18841 actggaggta gtgttatggc aggtctggtt tccttgttta acctctttgt tgcctttctt
    18901 atctgggcac catttgtcat gtcagctaat aaagaaaaag cgagtgacct ttcatgacag
    18961 caaaaaacgg agcaagcttt ttaatggcta taggattttt ccttattgcc attagtccaa
    19021 tggttggcaa caaataccta catatcgtga caggactagc ttttgttggc ttagggtatt
    19081 atctcactaa gcgcaagcgt ccttagtcaa tgcgagcagc tagcccctat gaaaagacaa
    19141 acctaagggc tagccttgat tttctatctt ggttatcgca tttaaaagca agcaaaaaag
    19201 caagggtaga tgcttacctt tgcttttttt attttttgac ctttaataga atatcttgct
    19261 acttaaacat ttaagacctt atctaaaaat tcaattaagc gtgggtgctt agggtgatca
    19321 aagatttcct ctggagtacc gtcctctagg aattggccgc cgtctgtaaa gatcacacga
    19381 ttagccactt gacgagcaaa gcccatttca tgtgtcacaa tcagcatggt catgccctgc
    19441 tctgctaggt ctttcataac gtttaagacg tctccaacca tctcagggtc aagagcagag
    19501 gtaggctcat caaagagcat gatatcaggg ttcatggcaa gacttcttgc aattgcaaca
    19561 cgctgctttt gaccacctga tagacttcct gggaaagcgt cagccttatc agctagaccg
    19621 accttctcta gaagagcaag tcccttttcc ttagccgcct cctttgagac ctttccaagc
    19681 tcaactggtg caaaggtaat gttatcaagg actgtcatat gtggaaagag attgaagtgc
    19741 tgaaacacca tgccgatatt ttcacgagcc ttatcaatat tggtattagg atctgaaagt
    19801 tcaaagccat caaccacaac cttaccacta gtaatggatt caaggagatt gagggtgcgc
    19861 aggaaggttg attttccaga gccagatggc ccgataatac aaacgacatc accctcgtaa
    19921 aatttagcat taatgccttt taagacctca ttttgcccat aggatttgtg taaatcttga
    19981 acatcaattt ttaattctgc cattagttaa gcctcttttc taaacgtttt gcaagccttg
    20041 ttaagagtgt aatcataatc aagtagataa ctgctaggat agcatacatg cggaaggatt
    20101 gatagtttct agcgataatg attttccctg tttggaagag ctccactaaa ccgatcgctg
    20161 agactatggt cgtatccttc aaggaaatga caaactgatt gatgaagttt ggcagcatta
    20221 gcttaatggc ctgaggaagg ataatccttc gcattgttgt gtgatatgac aagcccaagc
    20281 tgcgactagc ctccatttga cctgccggca cagcctcgat acccccacga acaatttcgg
    20341 caatataggc tccaccattt agcgaaagtg caatagtagc agctacaaaa tcgttaatcg
    20401 gtgattgatg cccagtcatg ctttcaatga ggtttggcac tccccagaag ataaaggcag
    20461 caacaatcat caaggggata ccacgcacca catcaacaaa gatagtagaa gccatgcgca
    20521 ggttctttga tggggataca gccatcattc caaaaacaat accaataacc aaagcaatgg
    20581 caaaggagat gagtgtcaga ccaagggttg ttccaagccc agccaataat tgcttgtagt
    20641 tattagctaa aagtccataa atagttgact catcggctgt tttgacagat gcctctgaat
    20701 caaggtatct gctgatgatg gcgtcgtatt ttcctgatgc tttaagagca gccaaaccgt
    20761 tgttaaacat ttcgatgagc tcagggttgg ctcctttttt aacagcaaaa ccatactcac
    20821 cagaaggctc tcccttgata ggaatatcaa gcttgtggcc tcgctgaata gcgtacctta
    20881 aaatagcttc atcatccata agcccgtcaa tagaaccaga atttaagcta tcgtacattg
    20941 aggaggcctc atcaaaggct tttagacggt aaccataaat atccttgttg ctttcaagga
    21001 aatcatagga ggctgttcct tttttggcac cgactatttt acccttgagg tccttgtatg
    21061 atttgataga gcttccggat ttgaccccaa ggcgaatgtt tgatgtgtag taggaatctg
    21121 aaaaatcaaa aatctcacga cgtgcaggtg tgatagacat acctgcaata acagcgtcag
    21181 cctgaccagc ttgaacagca tttaaagcag cgtcaaagcc aggattgctg atctcaatgg
    21241 taaagccttg ctgcttagca attgccttga tgaggtccat atcaataccg acatattctc
    21301 cgctgccaat ttgaaattca aagggagcaa aggaggagtc agccacgatt ttataaaccg
    21361 gctttaaagg agtggcctta gcagaggcat cgccagtagc cttgcctgct gtgaccttgt
    21421 cattgctgcc aagccatttt gtcatgatag cttgataggt tccatcagcc ttcatagcgc
    21481 ctaaggcttc attgaagtcg tcaatgagat aatcatagcc gctgcctttt ttgacagcaa
    21541 agccaaagct tccaatagcc tctcccttca tgttgatcgc aagatcctgc ttttggttaa
    21601 tggcatattg aatgacaggc tcgtcgtcca taacagcgtc aatagagcct gttgcaagac
    21661 tgttgtacat caggtcacct gtgtcaaatg ttttaacagt ataaccatac gattttttgt
    21721 atttatctaa gaaggcttga gcagctgttc catttttaac accgactgtt tttcctttta
    21781 gctcgctata tttcttaata gggttagcct ttcttgtagc aataacaatt tttgtatcgt
    21841 aatagggatc tgaaaaatgg aagacctttt gacgagcagc agtgatggtg gtgcctgcca
    21901 taagggcgtc agcttgacca gactgaatgg cattgacagc agcatcaaag ccagggaatg
    21961 tcatattgat attccaaccc tttcgctttg ctacttcatt gatgatgtca acatcaatcc
    22021 ccttatacac ctgatctgaa tccttgaatt caaacggtgc ataagcagta tcagaaacaa
    22081 tatcaattgt ctctgcactt gcaatcccag cagtcatcaa aacaactgac agcattgcaa
    22141 gcatccatgc ttttaatgtg tttttcatac tagtctcctt aataaaaata aaaaatatgc
    22201 ctaattatag cagatttttt tcaaacaagc aaatcatctc ttctttttat gtcataaaac
    22261 ctaacataaa caactaaaat agtcaaaaag ctttgataga gtctttaagt ccttaactat
    22321 gttacaatag ataagagata agatattgag gaccaataaa tgattgataa acgtgatttt
    22381 aaagcattta agctcgtgtc aaaatatgcc ccctcaggag atcagccgca ggcgattgag
    22441 accttggttg ataacattga aggtggtgaa aaagcgcaga ttttactagg agcaacagga
    22501 acagggaaaa cctataccat gagtcaggtg atcagcaagg tcaacaagcc aacgttagtg
    22561 gttgctcata acaaaacctt ggccggtcaa ttgtacggtg agtttaaaga gttctttcct
    22621 gaaaatgctg tcgagtactt tgtatcctac tatgactatt atcagcctga ggcctatgtt
    22681 ccttctagtg atacctatat tgaaaaagac agctctgtta atgatgagat tgacaagctg
    22741 cgccattcgg ccacctcatc gcttttagag cgtaatgatg tgattgttgt ggcttcggtt
    22801 tcttgtattt acggattggg ctcaccaaag gaatatgctg attcagctgt tagcctgcgt
    22861 cctgggcagg agatatccag ggatcagttg ctcaatgccc ttgtagacat tcagtttgaa
    22921 cgcaatgaca ttgattttca acgtggacgc tttcgtgtgc gtggtgatgt ggttgaagta
    22981 tttccagcct caagagatga gcatgccttt cggattgagt ttttcggtga tgagattgat
    23041 cggattcgtg aaattgaaag cctaacgggt aaagtattag gtgatgctga tcatttagtg
    23101 ctttttccgg ccactcactt tgtgaccaat gatgagcaca tggagcagtc tattagcaag
    23161 attcaggcag aattagcaga ccagcttaag ctatttgaag cagaaggcaa attgctagag
    23221 gctcagcgcc tgcgtcaaag gacagaatac gatattgaaa tgctacgtga aatgggctac
    23281 accaatgggg ttgaaaatta ctcacgtcac atggacgggc gttcggcagg agagcctcct
    23341 tataccctgt tagatttctt tccggatgat tttcttatca tgattgacga gagtcacatg
    23401 accatgggac aaattaaagg catgtacaat ggagacaagg ctagaaagca aatgcttgtg
    23461 gattatggct ttcgtcttcc gtctgcctta gacaatcgtc cgcttcgtcg ggaggagttt
    23521 gaaagtcatg tgcaccagat tgtctatgtc tcagcaacgc ctggagatta cgagatggag
    23581 cagactgata cgattgtgga gcagattatc agaccgacag gtctgcttga tccggaggtt
    23641 gaagtccggc caagcatggg acaaatggac gacttgcttg gcgagattaa cctgagggtt
    23701 gaacgaggtg agcgcacctt tatcacaacc ttaaccaaga aaatggcgga ggatttgacc
    23761 gactacctca aggaaatggg tgtcaaggta aaatacatgc atagcgacat caagacatta
    23821 gagcgtacag aaattattcg cgaccttcgt ttaggcgttt ttgatgtctt gattggtatc
    23881 aatctgctgc gtgaaggtat tgatgttccg gaggttagcc ttgttgctat tcttgatgcg
    23941 gataaggaag gcttcctaag aaatgaacga ggtttgattc agacgattgg tcgagctgcc
    24001 agaaatgctg atggtcatgt gattatgtat gctgatcgta tgacggattc catgcagcgc
    24061 gctatagatg aaactgctcg tcgtcgtgcc atacagatgg catataatga agagcatggg
    24121 attattccgc aaaccattaa aaaagatatt cgtgatttaa tcagtatttc cagagcagtt
    24181 gaagcaaaag caacagaagc agagacaaat tatgagtcaa tgacgcggtc tgaaagacaa
    24241 gaagctatta agcaattgca aaaaaacatg caggaagcag cagagctgct ggattttgaa
    24301 ttagcagcac agcttcgtga cctgatctta gagttaaaag caatggatta agacctgata
    24361 agctaagtct ggctgtataa gctaggcttt ttatctgctt ttgagtttgt cctttaggtc
    24421 tgtcttatga tctttggtac cagataaatg agtgatatct tgagcttgat ctacgcaaga
    24481 gctagtgcag ccactagctt cagactactt taatgattta atgaaagatt gattttgata
    24541 agacaattct gatataatgt aaagtagttg gcaaaaatag aaacattaaa taaattttct
    24601 ttttaataat ttaactttta ccttgtcaac aaggctattt tcggatagaa tttcttagta
    24661 cattatttca ctaatacaag aaggtaagta tgttaaaaaa caagtcaaga ctgcgagcta
    24721 ttttcgtttt tgttgggaag atagcgttgt tttacgtgat tttgatgctg ctcgtttatt
    24781 tttttggtta cctagggcat ggtcaaagta attttattta taatgaattt taggagattg
    24841 tctgatggtt aacgatatga ttgaaacaat tgagtatttt gcacaagcac aaccggattt
    24901 tccagtttat gattgcttgg gagagcgccg tagctatggg cagctaaagg aggactcaga
    24961 tagtattgca gcccttattg agagcttaaa gctaggtgaa aaatcacctg ttttagtttt
    25021 tggggctcaa agctatgaca tgctggcttc ctttgtcgcc ttgacaaaga caggtcatgc
    25081 ttacattcct gttgatgttc attcggcgcc agagcgtgtc ttgtctatta ttgagattgc
    25141 tcagccaagt cttatcattg ctattgagga gctgccggtt agtattgatg cgattagggt
    25201 ggttagctta gcagagatag aggcagctaa agcagccaag gcagccttta ccatgaccag
    25261 tcctgtcaag ggagatgaca attattatat tatcttcacc tctggaacga caggacagcc
    25321 aaagggagtg caaatttcgc atgccaatct tttaagcttt accaattgga tgattgagga
    25381 tgctgagttt gctattcctg agagaccaca gatgctggct cagcctcctt attcctttga
    25441 tttgtcggtg atgtattggg cgccgacctt agctttaggt gggacattgt ttgctttacc
    25501 caaggaaatg gtttcagatt ttaagcgctt gtttagcaca attgcggagc tgccgatagg
    25561 gatttggacc tcaacaccgt cctttgccga catggcaatg cttaatgatg atttttgtca
    25621 ggagaagatg ccaaggctga cccactttta ttttgatggg gaggagctga cagtatcaac
    25681 tgcaagaaag ctatttgaac gctttccaga cgcacgcatt atcaatgcct atggtccaac
    25741 agaggcaacg gtggcgttat cagcgatttc aatcactaaa gatatgatag agacttacac
    25801 acgcttgccg ataggctatc caaagccgga ttcgcctact tatatcattg atgaagctgg
    25861 caatgctctg gagccggggc aacagggaga gattattgta acgggtccag cagtttctaa
    25921 gggttatctc aacaatcctg aaaagacagc tgaagccttc tttaccttta atggcatgcc
    25981 tgcttatcat acgggagatt taggatcatt tactgaggac aatgtgttac tttatggtgg
    26041 acgattagac tttcaaatca aatatgcagg ttaccgcatc gaattagaag atgtgtcgca
    26101 gcagctaaac caatcaccgc tggttgaatc agcagtagca gtaccaaggt ataacaaaga
    26161 gcataaggtc caaaatctct tagcttatgt tgtcttgaag gacggggtga gggagcaatt
    26221 tgcgagagat ttggatatta ccaaagccat taaagcctct gttaaggatc atatgatggc
    26281 ctatatgatg ccgtctaagt ttatttatcg tgaaaagctc ccattgacac caaatggcaa
    26341 aatcgatatc aaattcttga ttaacgaggt taatcatcaa tgacgacctt gtttcatcac
    26401 ataccttata tggagcctta tggcaatccg atttattttg tctacctcat cattgctttt
    26461 cttccagtta ttattgggat ctttaagcaa aggcgttttt cgacgtatga aagctttgtc
    26521 agcctgatct ttattttgct catgtttggt ggagagcact atcagcaatt gcttgccttt
    26581 ttagcctatc taatttggca aaccatcagt gttttggctt acaagcacta tcgtcaaaag
    26641 gcaaatgcag cgtgggtttt ctatcttagc attttagcca gtctatttcc tttgatttgt
    26701 gtgaaggtaa gcctcagtct aacgaggtct ttctttagct tcttaggtat ttcctattta
    26761 actttcaaaa gcgttgggat gatcattgaa atgcgtgatg gggttttgac agattttagt
    26821 ctaaaggatt ttctacgctt tatgattttc tttccgactt tttcaagcgg gccgattgat
    26881 cgcttcagaa ggtttcaaga ggcttacacc aagcttccta gtcgtgatgt ttaccttgat
    26941 atgctcaata aggctgtcat gtatctcatg ctgggctttc tgtacaagca tattatctct
    27001 tattgcttgg gtgggctgct attgcccctt gctgaaaata aggctctgac tgtaggtggc
    27061 tactttaata aagagacgat ctatgtcatg tacctttatg ggcttaatct cttttttgat
    27121 tttgctggct actcgatgtt tgcgattggg ttgtcttatt tactggggat taagacacct
    27181 gaaaatttca ataagccctt cttatcacca aatttaaaag agttttggaa cagatggcat
    27241 atgagcctat cattttggtt tagggatttt gtttttatgc gattggtcca tctattgatc
    27301 aagcacaaga cctttaagaa tcgaaatgtg acttcgggct ttgcttacct gatcaacatg
    27361 ctggtgatgg gactttggca tggcttgacg tggtattata ttgcttacgg tctgtttcat
    27421 ggtattggct tgattgtaaa cgacgcttgg cttcgtaaga aaaaggaaat caatcgtcgt
    27481 cggaaaaagc aagggcttaa gcctttgttt gagggtaagg tatttcatgc tttatcaatc
    27541 gtggtcactt tccacgttgt cttgttctca cttctgttat tctcaggctt cttaaatgag
    27601 ctttggttta gcagaccgtt acgttaaaaa aggagagtat aaaaatgtct actaaagaaa
    27661 ctgtaattga cttatttgat cgcttgttta tggaagacgt atcagatatg atggacgagg
    27721 atttgtttga tgctggcgtt cttgatagcc taggaacggt tgagctgatt gtagagatcg
    27781 aatctatctt taacattaag gtgccaattt cagagtttgg acgtgaggac tggaacactg
    27841 ccaataaaat tattcagggc atagaggaat tgcagcatgc ttaaacggct ttggttaatc
    27901 ctaggtcctc taatcatcgc ttttggcttg gtttgtctta ccatattcag ctttcctact
    27961 aagcttagct attcattgcg ccaggaaaag tcaaatgcag tggcaatcaa tgatagctcc
    28021 tttaaaaacg gcttgattaa aaggcaggcc ttgtcagatc ctaactactg ttttgttccg
    28081 ttttttggct ctagcgaatg gagtcgcatg gatagcatgc acccatcagt gcttgcagaa
    28141 cgctacaagc gctcctacag accgttttta attgggaaaa gaggctctgc ttccttatca
    28201 caatattacg gcatgcagca gatttcacag gaaataactg gaaaaaaggc agtctttgtc
    28261 gtgtccccac aatggtttac cccccaaggc attgatcctg gtgcggttca attgtatcta
    28321 tctaatagtc aggtgattga tttcctctta aaagcaaagg ctagtcataa ggaatcacaa
    28381 tttgccgcta aaagaatgct ggacattaat ccgggagttg ctaaatcaga gcttttaagg
    28441 aaaattagtc aaggcaaggc cttgagtaga tgggacattc gtctgctcaa atggcagcag
    28501 gagctgtcct taagagagga gtccttgttt agcttccttg gtcgttcaac aaactatgag
    28561 gataggattt tgcctcgtgt taaagggttg cctaaaacct tttcttatga gcgcttgagc
    28621 gagctagcag ccagacgggc taaggaagga acttcaaata atcgctttgg catcaaaaat
    28681 gctttttatt ctaagcgaat tgcaccgcaa tttcctcttt ataagaattt tcagtgccgt
    28741 aataattaca ctgtgtcacc tgagtacaat gattttcagc tggtattgtc agaatttgca
    28801 aaacgtaaaa cagaggtgct tttcgttatt acacctgtta atcaagcgtg ggcaaattat
    28861 acaggcttaa accagaggag gtatcaaaag gctgtcagaa aaataaagca tcagttaacc
    28921 tcgcagggct ttactcgcat tgctgatttt tccagaaatg gcggagacaa gtattttatg
    28981 gaggatacca ttcaccttgg ctggaatggc tggctagcct ttgacaagga ggttgttcct
    29041 ttcttagagg atcaaacacc accatctgaa taccaactgg atccttactt cctatcaaag
    29101 gactgggcag atagaacagc aggattttag ggtcaataga ccattagaaa atgaggatta
    29161 gaattgttaa tgagtatcat cgtcatattg cttattttag ccattgctgt tttagtgatt
    29221 gagtatggtc aaaagcggtc cttttctagc tggctgcttg aaaagatgtt tgattatcgt
    29281 aagtataagc tctctaaaaa ggctgatgac tatgaaggaa ttgagacgca aagacgtcgt
    29341 cgcattccct accacttgga taatccagag gcggtattgg ggattcccac cacagaatat
    29401 acgattgatg gcatgcaggt ttttgtgatc aatgaccaag attctcagga tcagccagtg
    29461 atttactatc tttatggtag tgtctatttg cgtcgacctg agacatttca ctttaaaacc
    29521 attaagcatt tgatccattt aaccaatgcc aagctggtgt tcccaaattt tgagaaggcg
    29581 ccttatgtca cctataagga gatttaccca aagcttgcta aaacttatca ggagctttgt
    29641 ctagccaatg gcgctgccaa ggttagcatt attggtgact cctcaggtgg tggcatggcc
    29701 ttagccttgg cgcaatacct aagagatacc caaactgcac cacagccaaa gcaattaatc
    29761 ctgttatctc cttggttaga tgttagcttt gctaatcagg attataagca ttttgaagca
    29821 gtagaggctt atttagatgc taggcggctt cgagacattg gtgaattgtg ggcaggcagt
    29881 ccagaagaaa tgcggtctcc gtatgtcagc ccattatatg gcgattatca tgacctgcca
    29941 aagattgtca cttttgtcgg gacaaaagag attttttacc cagatattat gaccctgcat
    30001 gagcgcttga tggagcaagg gcacttaaat cagctcgtta ttgctgagca gatgattcat
    30061 gcttatgcga tcttcccgat acgagaggca aggcaggcgc gcaagcagat tgccgagctg
    30121 attttaaaga aggagtgatt gttgctatag gagtcagtta gccttgcttg tctgatgagg
    30181 cttgggcttg agatttctag agaagcttta aggcctttac ttgggctgtt aatgctcatt
    30241 aaagaggatt ataggcttta tactagggct taggattgct gttttgctat tcaataatat
    30301 tagtttagac ttgattgagg aaaggctagt tttagttatg gtcctcaatc tttttttgat
    30361 ggtaaacatg tcaagacagt ttacttgcta gggtaataat cctgtgctca tttcatgagt
    30421 ggctattttt atcctaagct tggtggtgga aaaatcagat taaaaaatat gaaatttgct
    30481 attgacagct gtaagcgatt gcattataat aaacttaact taaacgttta agttaagttg
    30541 aataagctga tttgatcatg cactgcctaa atgcaatcaa taatctcaaa gcatttggtg
    30601 tagtctagta atcaatgagg cagtttatta cggttataca atatttattt agttcatccc
    30661 tttaggaggt aaatagctat ggcgtgggat tggaaaaaag caggtgttgt tggagtagtg
    30721 tcattggctt cgatcatggt attaagtgct tgtagcggag gacatcaaaa agaggctaag
    30781 caaaaagacg acaataccat tgtagtttca gttgatgagg gctatgcaga ctacatcaaa
    30841 gagattaaga cagcctttga aaaggacaat aaggtcaagg tcaaggtcaa aaaggaaggt
    30901 atgattgata cgctagataa gctatctact gatggaccga caggtgcttc accagatgtc
    30961 tttttagcac catatgaccg ggttggtggg cttggctctg aagggcaaat tgctgaggtg
    31021 agcttaggca atgctgacca gtttgatgac actgttaaaa agctagtcac cataaatgga
    31081 aaggtttatg gggcaccaga tgttattgag accttagtga tgtattataa caaggatttg
    31141 gtatcagagg ctccgaaaac ctttactgac attgaagagc taaataagga tcctaagttt
    31201 gcctttgctt ctgaagacgg taagtctgta ggctttcttg ctaagtggac agacttctat
    31261 tatggctatg gcttgattgc aggctatggg gcttatgtat ttggagataa gggaactgat
    31321 ccaaaggatt taggtattgg taatgctggt gccattgaag gcttagacta tgctaagaaa
    31381 tggtatagcg tatggcctca aggcatgcag gatactcaaa aggctggaga ttttattaca
    31441 gagcaattca cctctaaaaa ggctggtgtg attattgatg gaccttgggc tgctgcctca
    31501 tttaaggagg ctggtgtaaa ctttggagtg gcacaaattc caagcttacc taatggcggt
    31561 agctatcaag cctttggtgg tggtaaagca tgggtgattt caaattattc taagaataaa
    31621 aagctggcac agcaattcct tgattatgtg acaaatgaga aaaaccaaaa agccttttat
    31681 gataagacac aagagatccc tgccaatcta gctgctcgca gctatgctgc agaacaagga
    31741 aatgaattga caaaggcggt tattgggcaa ttctcaaatg ctcagccaat gccaaatatt
    31801 ccagaaatgg cagaagtttg gggaccaggt gcgaacatgt tctttgaggt agcagcaggc
    31861 aagaagactc ctgccaaggc tgctaaggaa gcagctaaaa ccattcaaga ggctattgca
    31921 caaaaataca ctgaataaca taaaaaggga ggctgggata aaggtatcct agtctccatc
    31981 ttgttaccta tagtatcaga gtgggcgatg aggagataat aataaaaagt agtagtgact
    32041 agcttgtctt gtttcccatc ttgtcctaat aagagtatct gataagactg atgaacctag
    32101 ggaggaaaaa atgaacacag ccggaatact gcatattcca gattctagat attgctttgc
    32161 cttatcaaca aaggagcttg tgattcggtt gagggttgca aaggaggata acgatatagc
    32221 ggtgacgctg gtttatggac ctaagtatca ttatcatgag tatcaaaaag aactggcgat
    32281 gtatgctgct tataccgatc atacccatac ctattatgaa atcaccttaa gtcttgatga
    32341 tgttagattg gcctatattt ttaagcttga gcaatctggt cacacctatt actttagtga
    32401 ggatggcttg accacaagct atgatttttc aaatggcttt tacaactttt ttcaaatgcc
    32461 ttatattaat gctgtagacg ttcatcagac tgtcccttgg gtgcacaatg ctgtttttta
    32521 tcagatcttt gttgatcgct ttcatcgtgg tgactttgaa aaggacgata gctatattaa
    32581 tatggcttgg ctggataggc caactcctaa tagctttgcc ggaggggatt tgaaggggat
    32641 tacagataag ctggaatacc ttgaggatct tggtattaat gtcatttact tgacaccgat
    32701 tttcaaatcc atcagtaatc acaaatatga tattagtgac tactatgcta ttgacccgat
    32761 gtttgggaca tcgcttgatc tccagcaact aataaacgag gcccaccaaa gagggattag
    32821 aattatttta gatgctgttt tcaatcatgc tagcagtgat tgcgagccat ttcaggacgt
    32881 tttggcacat ggtagtgctt cttcattttt tgattggttt atgattcaag gagatcatcc
    32941 ttctgtagag ctagctaatt acgaaacctt cgctgattgt cactacatgc ctaagtggaa
    33001 tacctcgcat caggctgttc aggattattt gattgagatt ggtctttatt ggatcacaga
    33061 gtatcatatt gatggctggc gattagatgt ttctgatgag gtatcgcatg atttttggag
    33121 acgctttcga aaggctgtta aggcagtcaa atcagatgcg atacttattg gagagaattg
    33181 gcatgatgct tatccctacc ttcaaggaga ccagtatgat ggtattatga attacgcctt
    33241 taccaaggct tgtctcgatt attttgcatt tgatgcgatt agctcacagg aaatggctga
    33301 aagattgtcg catattttaa tgagaaatac ttggcaggtc aaccagatga atctgaattt
    33361 actggattcc catgatacgc atcgcttctt gactcaggtg aatggctcta aggacaaatt
    33421 attggctggc ttagcccttt tagttacctt tatgggcata ccatgtattt actatggaac
    33481 agagcttgcg atggagggag gttatgatcc tgactctaga cgtagcttta attgggacag
    33541 cagcacttgg gatatgagct tttggaatca ggttaaggac attatcagcc tgcgtcgtca
    33601 tgcggttatc caatttggaa gcatttcgat aacctcccat gatgactgcc tttgcgtaaa
    33661 gcgtgaatta aacggtcaat cgataagatt gctggttaat aatggcgtta agccatatcc
    33721 tattgagaaa ggaggttctg tgcttgtttc taatggtgta gataaagaga catttgagct
    33781 actccagaac gggtttgttg ttagctatta atatggcgtt ttatcaaagg aggttaagga
    33841 tgaagcgtat tactttaaca tgtcgtaaag cattaacagt agctatggca gcggttacct
    33901 tagcaatgtc aactaacagt gtctttgcta ttgaaaatac tgcggtgtct aataaggctg
    33961 atttttctac tgacacgatt tatcaaattg tcaccgatcg ttttcatgat ggtaatgctg
    34021 ctaataatgg aaatacagat gtatttgata aaaatgatcc taaaaaatat catgggggtg
    34081 attgggcagg tatcattaag aaactagaag atggctactt aaccaattta ggggtatcag
    34141 ctatctggat ttcatcacca gttgaaaaca ttgataccat tgacccttca aatggcagtg
    34201 cagcctatca tggctactgg gcaaaggatt ttttcaaagc aaacagtcac tttggaacaa
    34261 tggaggattt taaaaagctc attcaggtgg cacatggcaa aaacattaaa gtagttattg
    34321 attttgctcc taatcatacc tcaatagcag aatataatgg cttaaccttc cctgaggacg
    34381 gtgctttata taaggacggc cagctggttg gtaaattcag tcatgatgat caaaagattt
    34441 tcaatcatga atcatggact gatttttcaa cttatgaaaa tagcatttat cattccatgt
    34501 atggcttggc agacttgaac aatctgaatc caacagttga cgattatctc aaagaggcta
    34561 ttgataaatg gttagaaatg ggcattgatg gtattcgtgt agatgcggtc aagcatatgt
    34621 cacaaggctg gcaaaaaaat tggttgagtc atatctatga gaagcataat gtattcgcct
    34681 ttggggaatg gtttgctgac ggttctttta atgatccatt gatgactaaa tttgctgata
    34741 ctagcggcat gagcctgctt gattttaggt ttgctaattc tgttaggcgc ctgtattctg
    34801 atttatcagc gaaaatgcaa gatttttaca atatgattgt agctacggaa aaagagtaca
    34861 aggaagtttc agatcaagtg actttcattg ataaccatga tatgacccgc tttgctactc
    34921 tagtcaatca taatcagaca gctgttaatc aagcctatgc tttactgcta acatcgcgtg
    34981 gtgttccgaa tctttattat ggttcagagc agtatgctac aggtgctaac gaccctgaaa
    35041 atcgtggtga tatgccaacc tttgataaga attccactgc ttatcaggtg attagcaaac
    35101 tagcaccact gcgtaagaaa aatcaagccc tggcttatgg tacaacacag cagcgctgga
    35161 ttaatgatca ggtcttggcc tttgaaagaa aatttggaaa tgacgttgct ttagtggctg
    35221 ttaataagga tcaaacaaat ggctacacaa ttagtggcgc taaaacggct ttaccagctg
    35281 gtaagtatgc tgatgaatta ggtggcttac tgggcggaaa ggaattaacg gtatcagctg
    35341 atggtaatgt tgaggcattt gagttaggtg cgggtcaggt tgcagtttgg acctttaaag
    35401 ggcaacatga gacaccgcag ataggagacg tagacgcttc gtttggcgtt gcaggaaata
    35461 ctgtctctat ttcagggcaa ggatttggta gtgctcaagg tcagcttcat tttggtgata
    35521 gcaaagcaga tattgtgtca tgggacgata ccttgattca atttaagata cctgctgtag
    35581 ctgctgggaa ccatgatatt aaggtgacca catctacagg acaaagcagt agcccttaca
    35641 aagcctttga agtgttaaca gataagcaaa ttccagtaag attggtggtc aataatttca
    35701 acactgtatt aggtgagcag ctttatatcg ttggtgatgt ggttgagctt ggggcaaatg
    35761 ataatcataa agctttaggg cctattttta atgcaacaca gtcaattgcg cagtacccaa
    35821 attggttcta tgatgtcaat ctgcctatta acaaaaccat taactgtcat cttgtaaaga
    35881 aggatagttc tggtaaagta ttgtggacta gtccagaaac ctataccatt aaaactgata
    35941 gcaaggctca aaccatttca ttgaaaaaat agttgcgtta tctgtgatgt tatttaatac
    36001 tctatgaagg aggagaacca taaaagggtg atagagagga atgacaaatg cttaagaatg
    36061 aaaaaatgaa gaatccacaa aaagccatgt ggctttcaat aatccctggt ctggggcaac
    36121 tctacaatac tcaaaaggta aaaggcttta ttttgcttct tgtgttttta ggtgagctgc
    36181 tagaggcttt ctttgttggt attccggctc ttgctggctt gtacagcctt ggtagtgtac
    36241 caatggagga tcattcccta ttcttattga ttaagggagc tatgcagctt atcctatttg
    36301 ccttgttttt gatctttcat ttggctgcta tgcgagatgc tagactagtg gcaagggaga
    36361 tcaatgcagg ccatagcatt tcattaacct taaaggagat ggtacaatcc atctatgaaa
    36421 agggctttcc ttatttgctg attattccag cctacttggc catggccttt gccattgttt
    36481 ttccggtgct tgttacttta ttaattgcat ttacaaacta tgattttagg catattcctc
    36541 cctataaatt attagattgg gttggcatta agaattttaa aagcatttta gagcttagca
    36601 cctttaagtc agcctttggc tctgtgctgt catggacctt gatttggacc ttggcggcaa
    36661 cgagtctcca gattgtgata ggaatagcga ctgctattat tgccaaccag tcctttgtga
    36721 agtgcaggcg catttttggg gtgattttct tgctgccttg gggggtgcct gcttttatct
    36781 cgatcatgag ctttggtaat ttctttaatg attctatcgg tgctatgaat gttcaggtct
    36841 taccattttt agaaaagttt gtgccatttg cagattttgg gattatccca tggaagacag
    36901 atcctttttg gacaaaggtt gcggtgatta tggttcaggg ctggctgggc tttccttata
    36961 tttatatttt ggtgtctggt attttacaat caattcctgc tgatttgtat gaggcagcaa
    37021 cggttgatgg tgcaacagcc ctgcagaagt ttcgccaaat taccttgcca atgatctttg
    37081 ctgtcgcagc cccgacctta atctcgcagt atacctttaa ttttaataac ttctccatta
    37141 tttatctctt taataatgga ggtcctggta cagttggcgg tggcgcaggg tcgacagata
    37201 ttttgatttc ttggatttac aagctgacca cacaaacgtc accacagttt tccattgctt
    37261 cagcggtgac cttaatcatt tccttgattg ttatttctgt atcattgata acctttaaaa
    37321 aattcaaagc ctttgacatg gaggatcgct aaatgggtag gaattatttg ccacagtcag
    37381 tgaagaagaa gcgcttgtta gctcagctgt tgacttacag ctatttgcta atcctgtcga
    37441 tcatcatctt atttccaatc ttggtgaccg ttagctcagc ctttaggcca ggaaatacaa
    37501 ctgcctttag ctttcatatt gatgggcctt ggaccttatc aaactttgag acactctttc
    37561 aggacaccta ttacttaaga tggtactgga acacgttagt tgtcgccttt ttcacgatgc
    37621 tgatccaggt gacagtcatt acgctgacag gctatgctta cagccgttat cacttttttg
    37681 ggcgtcaaaa gagtttggtc tttttcttag tggttcagat ggttccgaca atggctgcct
    37741 taacagctta ttttgtgatg gcttggttgt ttaatgctct gaatcactat tggttcctca
    37801 ttctgattta tgttggagga ggcattccga tgaatgcttg gttgatgaag gggtattttg
    37861 atactgtgcc ttatgattta gatgagtcag ctaagctaga tggctctggt cactttagga
    37921 ccttctacca aattgtattt cctctggttc gtcctatggt tgctgttcag gccctatggg
    37981 cctttatggg gccatttggt gactttatgc ttgctaagtt tctcttgcgt gaacaggagc
    38041 attacaccgt agcggtaggt cttcagtcat tcatcactaa cgacgctagg gatcctaagg
    38101 tcacattgtt tgcagccggg gccattttaa ttgcagtgcc aatttcagtg ctattcttct
    38161 ttttacagaa gcattttgtt tcaggcttaa ccaatggtgg aacaaagggt taatttatct
    38221 ttcaaggagc ctttatcatg actaatgatc gatttcctat ttcttacaca accattattt
    38281 tttctcctaa aatgatattt gctcgttgca gtgccttttt gtggtggcag aatgtgattt
    38341 tagtgatctt tctaaatgct ctggtgttaa tgccgatcac gctgcattat gcaagcttga
    38401 agagctatcc cttagagcac atagttagta atggtttaga ctccttgaca gaaaaaacct
    38461 atcatgcctt gacacaaggc actatttggc atgatcgcta tgatggaaaa acagtcctta
    38521 tagaggatac tgatgctgtt gttgctgtat tgccaacacc agaaatagta gaagagctaa
    38581 agaaagatca aagaagccag ctgatattaa cagaaacctc atggatttta agctttcctg
    38641 atggtcaaag gctaactgct aaggttaaag gcaacaagga aaggctaacg cgcttaacct
    38701 ctctagaggc tgtcaaggcc tttgttaatc agcaatggta caatagcaat cgtgccgctg
    38761 tgcttgcctt tttgctgcta gtggctagca gtgtggtcta tctaggagcc ggtttagtga
    38821 tcggaattgg ctcgttatca ctgttattaa caagatctgc tagattattt tcactcaaga
    38881 gctactcaga atgcttgggt ttgctagtga attgctttgg acttcctacg cttttagcag
    38941 tgcttataag tttttgggtg cacaatccta ttgttatcat gaatagtcag gtctttggca
    39001 cactgctcat gctggttcta gtcttttaca aaactcagtt tagagatgag gagcaagcac
    39061 tagcttagcc cttgctgaca tcaaaaaatc cctcc
//
LOCUS       DARYXZ010000017        38468 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYXZ010000017 DARYXZ010000000
VERSION     DARYXZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38468
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(36..1367)
                     /locus_tag="TV186_000767"
     CDS             complement(36..1367)
                     /locus_tag="TV186_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL1532180.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1458..2237)
                     /locus_tag="TV186_000768"
     CDS             complement(1458..2237)
                     /locus_tag="TV186_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL1532181.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2268..2912)
                     /locus_tag="TV186_000769"
     CDS             complement(2268..2912)
                     /locus_tag="TV186_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL1532182.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2918..3568)
                     /locus_tag="TV186_000770"
     CDS             complement(2918..3568)
                     /locus_tag="TV186_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL1532183.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3583..4773)
                     /locus_tag="TV186_000771"
     CDS             complement(3583..4773)
                     /locus_tag="TV186_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL1532184.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4965..5867
                     /locus_tag="TV186_000772"
     CDS             4965..5867
                     /locus_tag="TV186_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1532185.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(6764..7906)
                     /locus_tag="TV186_000773"
     CDS             complement(6764..7906)
                     /locus_tag="TV186_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532186.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(7903..8766)
                     /locus_tag="TV186_000774"
     CDS             complement(7903..8766)
                     /locus_tag="TV186_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532187.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(8777..9103)
                     /locus_tag="TV186_000775"
     CDS             complement(8777..9103)
                     /locus_tag="TV186_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL1532188.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(9707..9871)
                     /locus_tag="TV186_000776"
     CDS             complement(9707..9871)
                     /locus_tag="TV186_000776"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532189.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(10110..11006)
                     /gene="era"
                     /locus_tag="TV186_000777"
     CDS             complement(10110..11006)
                     /gene="era"
                     /locus_tag="TV186_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL1532190.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(11142..11543)
                     /locus_tag="TV186_000778"
     CDS             complement(11142..11543)
                     /locus_tag="TV186_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1532191.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(11524..12021)
                     /gene="ybeY"
                     /locus_tag="TV186_000779"
     CDS             complement(11524..12021)
                     /gene="ybeY"
                     /locus_tag="TV186_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL1532192.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(12370..12996)
                     /locus_tag="TV186_000780"
     CDS             complement(12370..12996)
                     /locus_tag="TV186_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1532193.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(13051..13626)
                     /locus_tag="TV186_000781"
     CDS             complement(13051..13626)
                     /locus_tag="TV186_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL1532194.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQAPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(13673..14773)
                     /locus_tag="TV186_000782"
     CDS             complement(13673..14773)
                     /locus_tag="TV186_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL1532195.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(14876..15091)
                     /locus_tag="TV186_000783"
     CDS             complement(14876..15091)
                     /locus_tag="TV186_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL1532196.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(15088..15597)
                     /gene="msrA"
                     /locus_tag="TV186_000784"
     CDS             complement(15088..15597)
                     /gene="msrA"
                     /locus_tag="TV186_000784"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL1532197.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(15935..16792)
                     /gene="cvfB"
                     /locus_tag="TV186_000785"
     CDS             complement(15935..16792)
                     /gene="cvfB"
                     /locus_tag="TV186_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL1532198.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(16926..17483)
                     /gene="frr"
                     /locus_tag="TV186_000786"
     CDS             complement(16926..17483)
                     /gene="frr"
                     /locus_tag="TV186_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL1532199.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(17520..18248)
                     /locus_tag="TV186_000787"
     CDS             complement(17520..18248)
                     /locus_tag="TV186_000787"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL1532200.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(18547..19227)
                     /locus_tag="TV186_000788"
     CDS             complement(18547..19227)
                     /locus_tag="TV186_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532201.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(19214..20002)
                     /locus_tag="TV186_000789"
     CDS             complement(19214..20002)
                     /locus_tag="TV186_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532202.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(19990..20796)
                     /locus_tag="TV186_000790"
     CDS             complement(19990..20796)
                     /locus_tag="TV186_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1532203.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(20781..21722)
                     /locus_tag="TV186_000791"
     CDS             complement(20781..21722)
                     /locus_tag="TV186_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1532204.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(21800..23422)
                     /gene="nikA"
                     /locus_tag="TV186_000792"
     CDS             complement(21800..23422)
                     /gene="nikA"
                     /locus_tag="TV186_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL1532205.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            23924..25564
                     /locus_tag="TV186_000793"
     CDS             23924..25564
                     /locus_tag="TV186_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1532206.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGKKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(25808..26497)
                     /gene="rplA"
                     /locus_tag="TV186_000794"
     CDS             complement(25808..26497)
                     /gene="rplA"
                     /locus_tag="TV186_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL1532207.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(26603..27028)
                     /gene="rplK"
                     /locus_tag="TV186_000795"
     CDS             complement(26603..27028)
                     /gene="rplK"
                     /locus_tag="TV186_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL1532208.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            27264..28061
                     /locus_tag="TV186_000796"
     CDS             27264..28061
                     /locus_tag="TV186_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1532209.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            28216..28566
                     /locus_tag="TV186_000797"
     CDS             28216..28566
                     /locus_tag="TV186_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL1532210.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(28895..29350)
                     /locus_tag="TV186_000798"
     CDS             complement(28895..29350)
                     /locus_tag="TV186_000798"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532211.1"
                     /translation="MTISDQKVNASQYRWRQYYYRMSPTERELKKEKEVLRNFIATIK
                     LSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKISNKVEIVSSLIDEHFPEGH
                     SRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIMTRKKLWYIQ"
     gene            complement(29725..32124)
                     /locus_tag="TV186_000799"
     CDS             complement(29725..32124)
                     /locus_tag="TV186_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL1532212.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
     gene            32244..32417
                     /locus_tag="TV186_000800"
     CDS             32244..32417
                     /locus_tag="TV186_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532213.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            32504..33310
                     /locus_tag="TV186_000801"
     CDS             32504..33310
                     /locus_tag="TV186_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL1532214.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(33466..34299)
                     /locus_tag="TV186_000802"
     CDS             complement(33466..34299)
                     /locus_tag="TV186_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1532215.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(34300..35025)
                     /locus_tag="TV186_000803"
     CDS             complement(34300..35025)
                     /locus_tag="TV186_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1532216.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            complement(35085..36017)
                     /locus_tag="TV186_000804"
     CDS             complement(35085..36017)
                     /locus_tag="TV186_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL1532217.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            36163..36810
                     /locus_tag="TV186_000805"
     CDS             36163..36810
                     /locus_tag="TV186_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL1532218.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
     gene            complement(36866..37567)
                     /locus_tag="TV186_000806"
     CDS             complement(36866..37567)
                     /locus_tag="TV186_000806"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL1532219.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(37591..37839)
                     /locus_tag="TV186_000807"
     CDS             complement(37591..37839)
                     /locus_tag="TV186_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532220.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            complement(37839..38393)
                     /locus_tag="TV186_000808"
     CDS             complement(37839..38393)
                     /locus_tag="TV186_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1532221.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
BASE COUNT        11830 a         8872 c         6943 g        10823 t
ORIGIN      
        1 aatagaccaa tggttttcca ttgatctact gtgtattaaa aaaacaggct agttaacata
       61 ataatgctct cggccaccaa cgtaccacca aaaactgtaa taaaggtttg tttaaagcca
      121 tttttatggc tgagaccagt aaggctcaag aaggttaaaa agacgccaga ctggggtaca
      181 atggtcaaaa tattagaggc aacagctgcc acacgatgaa tgatctcagg tgaaacgcct
      241 gcatctaaat aatattgagc aaaatttggc attacgatcc ctaacgctcc tgaagacgaa
      301 cctgtaatag ctgccatagc cgaagtcagg acagtcaagc tgatcacagg tggcccagga
      361 atattcaaaa tgatgtctga gaatacgcca aaaccagatg ctgctgtaac aacagaacca
      421 aaggctactg cagaggctgt cgcaaagatt ggaccaaccg caccgctagc accaatgctg
      481 agggtcgcaa ttttcttatc aatgtacttg ttaaataaaa cgatagctga aataattcct
      541 gtcaagaggg ccacataaat gatatttttc ttaacgaatt cgtcccctag cagactacct
      601 atgatggcaa taacaatcaa gagtatcaaa ggcaagatgc tgactacaaa tggtggtaaa
      661 accctttcag ttgtatcttc atttgtttga ctagtatagg tcgcatagtt ttcgccaact
      721 tctaaactct tagtcaaaca acgcttcata tagaaaagac caaaggcgat acagccaaca
      781 ctccctaaaa tacttggcac caaggctgcg gttagagacg tgttaagata ttgtataggg
      841 ataacgtttt gaatcgctgg tgtaccaggt aagatcgtca tagtaaaggt tgcaatcccc
      901 aaccaaagtg gtacttgaat taagttccat gctaagtcca tctttttaaa gagagagcgt
      961 gccaagggta gaacagcaaa catgaccaca aagagactaa taccaccata agtcaaaata
     1021 gcactgatga taaaaatagc caccaagata cggtaagggt tttgataacc tacttttttc
     1081 aagataaatt cagcaatgga aactgttgca ccactgactt ccatcaattt agctaaaata
     1141 gaccccaaca agaagatagc aaagtagctc atgatatagc cacccagcgc acccatatag
     1201 ttatttggtt ccttacccaa gagtgactca actagtggca tactatttag aaggacgacc
     1261 aaaatcgttg ccataggagc cgcaatggta atatgaattt cctttagaga aaaataaacg
     1321 atggcaataa tgcccagcaa gaccccaatt ggtcctaaaa attccatagt gtttctcctc
     1381 tcacattcag aaggagcaag agatagagaa atgtcactct atctccaatc ctcttattta
     1441 cactgaacgg acagctctta ctgagcagtg tagccaccat ccaagataac cggttgtcca
     1501 gtaattccct ttgccttatc acttgctagg aaggagacat aatctgcaat ttcttgtacg
     1561 tcaatcaaac gtttttgcgg taccaacggg tacaacactt cttccaatac attttcaagc
     1621 ggaatcttac gtgtcttaga gaggtcttca aattggccac gaacgagtgg tgtgtccaca
     1681 tagcctggac agatagcgtt gactgtgata cctaattctg cggcttcaag cgctgcaacc
     1741 tttgtcaagc caatcaaacc gtgttttgct gaattgtaag ccgcttttcc ggcaaaacca
     1801 atgacaccat tgatagaagc catattaatg acacgaccaa agccttgctt tttcatagtt
     1861 ggaaaagcgc gcttaatagc gataaatggc gctgtcaaca tgaccttcaa cataaattca
     1921 tattttgctg ttggaaaatc ttcaatcatg gcaacatgct gcaaacctgc gttgttgacc
     1981 aaaatatcca aacgaccatg cttttcaact gtataatcaa tcgctttatt gatcgcttct
     2041 tcatttgtca catcacacaa aacagaatca gccgcccagc cttttgtggt atactcatca
     2101 acaacagcat ctaatttttc ttgattgata tctgaaaaga caacgatttt gccctctttt
     2161 aagaatgttt caccaatttg tttaccaata ccgcttgctg cacctgttac gaatactact
     2221 tgtttagaca tatttatttc ctcacttttt ttaaatattg ttttctatca gttatgataa
     2281 attaatcttg cttcggtggc ttcttgaact tcttcaaagg tataatctgg atgaatttct
     2341 tctactgcga ttccctctgg agtgactgtg aagacaccca tttctgtgac aatcttgtca
     2401 acaactcctg ctgctgtcaa tggcaatgaa cactccttca agattttcca tttgccttta
     2461 ttggtatgct ccatagcaac aatgactttt ttagcaccga ctagtaaatc catggcaccg
     2521 cccattcctg gaaccatttt ccctggaata agatagtttg cgatgtttcc tttttcatca
     2581 atttgcaaag cgccaagaac tgttgcatcg acgtggccac cacgaatgat cccaaatgaa
     2641 gtggtgctat caaaaaatgc tccgcctggt acgatgccaa ccggctgacc acctgcatta
     2701 actatagttg gatcaatgtc atcgcctact ttatctaagc cgacaaaacc attctcagac
     2761 tgcagcatga tagtcacacc ttctggtaaa aatctagcta ccttggttgg caagccaatc
     2821 cccaaattga ccagggaatt atttggaagc tcgagtgcca cacgtttagc aattcgttct
     2881 tgaatttctt ctttgcttaa ttctttcacc ataacgctca ttctccttcc actagataat
     2941 tgacaaatat gcctggtgtt tgaactgcaa tgggttcaat gtctccaagc gagacaattt
     3001 cacgcgcttc aacgatggtc acttttgcat ttgctgccat aacctggttg aaattatttt
     3061 cagagccctt gtagcatagg tttcctaatt catcagcctt atctgcaaaa attaaagcga
     3121 cgtcagcttt caatggtaat tctaacagat aatccttgtc attgacctgt aatttttgct
     3181 taccttcctc taccaaggta ccgatgcctg tcggagtcaa gaagccaccc agtccgtaag
     3241 ctcctgctcg gattctttca gccaaggttc cttgtggcac taagtcaatc actgtttcac
     3301 cggctgtcat ttggcggcct gcttctttgt tcaagccaat atgagaagcg ataattttcc
     3361 gaaaccgatg ttgtgctacc attttaccga cacccttgtc tgggaagcct gcatcgttac
     3421 aaataagagt taaatttgta actccttttg ctaccaaagc gtcaatcagg cgctctggac
     3481 tcccgttagt cataaaacca ccaaccatga tggtgtcgcc atcctttaca aggttaacag
     3541 cttcttctat gctaattcgt ttattcatga aaccatctcc ttttattttt caatcaatac
     3601 agacgtccct tgaccgccac cgatacagag tgttgccaat cctttatgtg cctgacgctt
     3661 ttccatctcg tgcaatagtg tgaccaagat acgcgcaccg ctagcaccga tcggatgacc
     3721 aagagcaata gcaccaccat tgacattgac gatagccgca ttaagaccaa gctcatctac
     3781 aacactgata gcttgtgagg caaaggcttc attggcctcc accaaatcca agtcttcaat
     3841 tgtccaacca accttagcaa gggccttctg agtggaagga attggcccag tacccatgac
     3901 ctctggtgct acaccagcac ttgcataacc tttaatggct cccagaattg gaagaccaag
     3961 ttcttcagct ttgtcacgac tcatgagaag gacagctgcc gcaccgtcat taattcctga
     4021 agcgtttcct gcagtaacag ttcctgaacc atctcggaca aaggccggac aaagggctgt
     4081 taatttttca agggttgttc cagctttaat gtactcatct tctgccacca aaattggatc
     4141 acctttacgt tgcggtactg gcactggaat aatctcatct acaaagcgac cagcggcctg
     4201 cgcagcagca gctttttcct gactagccaa agcaaatata tcttgagctt tacggctaat
     4261 cccatagttt tttgcgatat tttctgctgt aattcccatg tggtaatcat gaaaggcatc
     4321 tgtcaaacca tcattgacca tagtatcaat gatttttcca tcgcctaagc gaccacccca
     4381 acggtaatct ttgagcacat agctggcttg gctcatattt tctgtcccac ctgcaataat
     4441 gatatctgaa tcaccacaga cgatactttg tgctgctaac tcgatggatt tgagaccaga
     4501 accacagacc atatccacag tgaaggcagg tttgtcgttt ggaatacctg cagttatccc
     4561 tacctgtcta gcaacatttt gaccgagtcc tgcatggagg acatttccga aaatgacctc
     4621 gtcaatttgt tcaggcttca cacctgattt ctctagtaat gcttctacaa ccacttttcc
     4681 taattgaaca gccgagacag atttaaaggc tccaccaaat gaaccaatgg gtgtcctaac
     4741 agctgtagtg ataacaactt ctttaaccaa catgcgattc tccaatctat ttgttataga
     4801 aagcgctttc tgtttttgtg aatttatttt atcactacta aaagcgtttg caaaattcga
     4861 tttttttata tgactataaa aaatttttat tattttttat tgacagctat aaaaattatt
     4921 attagtatga agaaaaagac atctgaaatg aaagaagagg caatatggat attaaacatt
     4981 tacgcttttt cattgctatt gtagaaaata attttaacct gagccgtacc gctcaacagc
     5041 tttatatttc ccagcctacc ctcagtatta tgattaatga ttttgaagaa aagcagggca
     5101 ttaagctctt caataaaaaa tacaataaaa tcctcggctt aaccatgaca ggcaagcaat
     5161 tttatgagga ttctttggag gttatccgca aatatgacaa gatgcaccaa aatctctttt
     5221 ccaccaatca aaagttggac ggtaatatca ctatcggcat tcctccatta attctgtcaa
     5281 ttgttttttc aaaaatcatg ccagaaatta ttctagaaaa tcccaatatc cactttaata
     5341 ttaaggagta tggtgctaat cggctacgtc aggaattgat tttagagaat gtggatatcg
     5401 ccattcttct gcatcctgaa cgaattgctg caaacaccat tgattctttc caaatccaag
     5461 aatctgagct ctgtgcattt gtctccaaga accaccattt ggccaataaa aaaatcctga
     5521 cttggataga actccacaat gaaaaactag ctatatttga taaaaccttc atgattcacc
     5581 atctcatcaa ggaaaaatgt aagtatactg acattaaccc ccaaatcatt ctggaatcag
     5641 cttcttggga ctttctgatc aattctactc gtatcaaccc tcaactaatg acgattattc
     5701 caaaaccaac ggtagatagc tatggttttc aggatattgt ggctattcct atggagaatc
     5761 ctattccttg gaaagtcatg gttagtcgtc tcaaaaaaga tcattattcc accatagaag
     5821 aatacatttt caacaaaatg cttgaaaaat ttcatgtaat cgaatagaga ctaacaagtg
     5881 atccctttca catgactgca cgtgcccttc gacatatggc acctcaacta acccttagcg
     5941 catatggaaa cagctcaatt ctttttgaag gataaaacta aagaggcttg acgatccata
     6001 ctaactcaga cccaatatta ttatcaagat cctaaatatt aacacaactc atttataaca
     6061 attaacttac aaaaaatggt ctactccttt gaggcgtgac agcaatactg caatttataa
     6121 aaaatgactg tcaagacaat atctctgaac tcagtcactg tttctcaaaa atcactcaca
     6181 tctaatggag tactatcaag aaaaagttat ttttaaaatc atcaataacc tatctaaatt
     6241 ttctaaacaa tgccatataa aaagagctgg agtcaccaag ctctaattga tttttacatg
     6301 atgctctata acaatatcgt ttaaagatca ttctttttta ctagtatgtt gatcacattt
     6361 tctaaaagcc agaaagagac ttgaataccg agtccctttt ctttttatct ataaacagcc
     6421 ttaaagaagc ccagacaggc tgcggtaatt ttcttaacat gagcttctac tatttctctt
     6481 gttaagccct gctcacttga tgattcgtta tttttaccac ctgaagactc tcctctacat
     6541 aggctacttt gtcatctagt tcctgcttct taacgatata tcatcgtctc aattgatgcc
     6601 acttccctta tcatcttaga aaaaagctaa tttctatacc tttaggtgtt ctagatcaca
     6661 aaatagcttt ctcaatccta tctaccttgc aagaattcat tgaatgccct taacttttgc
     6721 agtaacgaca ataaaaatag tttagataac gatgctattg atgttactga cttaccctct
     6781 ttattgataa gtatgctaaa tataagcaaa gaaatgcaaa agctaatcta atcatgacaa
     6841 taactaatcc atcaacccaa aaactgccaa aaaagccgtc ataagcaagc ttaagcatta
     6901 tgtttggtgt actcgcagtt gatacagata aaatactcaa caccttatga ggtattcctg
     6961 cttggaaaat atccataaga aaacttggta caaaaacact agccgcagac aaggcaaaac
     7021 ctgtcaatgg agacttaacc ttacttgaaa taaggatagt gatagccgta atcaggataa
     7081 gcccaataaa ctgataggtg actagattga taaatgttcc caaaagagtc attttttctg
     7141 gaaaagccat tatattcaca ttgctgttaa tccaatacag attgagttga acactcgtgt
     7201 cccaaccact taatccaaaa taccaaacaa agaccgctaa tattatggcg taaaaagtaa
     7261 caaacactga ggtgcttatc aagtaactac ttattatctt ggctatcgta agtttattac
     7321 gaccatacct agttgtcaat aaaataggat tcatattttt agcagtatca ccggaaaaaa
     7381 caggagcgat gaagtaaaca gacaaaagaa gaagaaggat ataagcacta tttatgacca
     7441 gaaaaagctg attccagggt gcaaaattac ccaacttcag ctctttaaag ggaagataag
     7501 agccaagagc cgtttgagat tttggggtga tcttactgaa atcaatagtc tcttcttttt
     7561 tcaaattaaa ataataatct ctaaattttg gatcaaaatg gctagttaca tagtagccat
     7621 acacattgaa gacaggattt tttgagctgc cacctagagt ataatctttg attgttctaa
     7681 ttaataactc attggacaat tgaccggtat gttcttccgc aaatcgcttg tttatctcaa
     7741 cagcatctct tccatgaatt ttatctatcg aagaaccact gatttgtcca ttaaaaaagt
     7801 tgatataaaa taacccaaag attgctaata agctaacaat aaacattccc aaaactgatt
     7861 tggttcggat cagttttttt aattcaaatg gtaagagagc tttcataaca cctgttcctc
     7921 tctaaagtga taaatgtata agtcttctaa ggttggtgac actagttgag ccaactgatt
     7981 tggtttctca tcactaacca cacgaaaaac acgactagat gaaactagtt tctcattgac
     8041 tacagcatac tgaccatgcc ttggtaacgg cgaaccatca gagacagaaa actcccagac
     8101 cttgccaaag atggttttca acaattcttg actactactc ttatggataa attgaccatt
     8161 ttttaaaatg ataatctcct tagcaatagc ctcaacatca gagacaatat gagttgataa
     8221 gataataatt ttgttggccg acaattcgct aataatattg cgaaacttca ccctttcttt
     8281 tgggtctaat ccaactgtcg gctcatctaa aatcaagatt ttagggtcat tgagtaaggc
     8341 ctgggcaata ccgagacgtt gcttcatacc accagaataa gaggcaatcc gcttcagacg
     8401 gacatcatat agatccacaa gttttaacaa ttcatccgtt tcttgcttgg ctttatgttt
     8461 aggtattcct tttaaggctg ccatataaag aagaaagtct cgaccagaaa aacgaccata
     8521 ataactaaac tgttgaggca aaaaaccaat atgctgataa aattcctctg attgaggttt
     8581 gtgatccagt aaaatctctc cttcatcagg agtcgtaaaa tgactaatga gattgagcaa
     8641 ggtcgttttc cccgtcccat tagcccctaa aagtccgtaa aggcctgggg tgaattgagt
     8701 agtaatcctt cgcaaaatat ttttcgatcc gtagctctta ctcaattgat ttaattctaa
     8761 taacatagaa ccctccttaa atgagtctac tgagcacctg taactcagta ctcagtagac
     8821 ttctcctgta cgaaatcctg ctgtctgtaa cctttattat tctcgtagca taatcaaatc
     8881 cagagatttt cgattcatta atgaaatatt gacgatgaca cctttttaat ttcccagcac
     8941 tttctccctc aatctgtctc agtgacgtag ctgccccaaa ttcccctttt agggtaacaa
     9001 atactactgt gtgaggctta gatgaatgtg ttgtcacatc ataggtttca gagattggta
     9061 atttaacaac tgacctattc ttatataaaa taacatattt cattgacgtc ctccttctct
     9121 atttatatct taatacaagt acaagcattg agacggtaaa gtctcaaatg gtatctatca
     9181 tatcctgaat ggtatcacag tagctgttta agatgtcata gaggcatttg agaaatgtaa
     9241 cctgttttcc tttcgttttt tgatcatatg atattgtatt agttcggaga accatggtaa
     9301 tcattcaaat cttacataaa cctctcttgg gatatggtat tagcgtctat attaattact
     9361 acttcaacag acaccttttt aaagctgcta aaattgtcag tggcaaacaa ataggctata
     9421 ggtataaatc tcacacttat tttatcataa aatcattctt tttatcatct aatcaaatgt
     9481 acaagcactt taaagttatt ctcatgactc tattattctt attggaagcc atattaatta
     9541 cgacgacatt ttcagaaatc attatcgtgt gtttggtatc atcgacacaa ccgctaataa
     9601 atcgtttaaa tgtatccaaa accaaattca tgattacctg ttcaaagaat aaccagaggg
     9661 cttactgatt gctttaacaa atatttctag tcttctcatt ttgtactcat ataaactcat
     9721 ctactctatt aaaaattgct gtgaacagaa aaaccttctc aacctgtttc agttttatag
     9781 ccgtagttag tttaaagtga aaccaccctg cattttctat acctaaatcc aattgacttg
     9841 ctttttcagc atcaacagtc atgctatcca taagataaca caccacgatg tgttgtgatt
     9901 attgttcttc tatatttagc cttacctcct gaaaacaaaa aaagagaaca ccttttaaat
     9961 gttctcatat aagcaatctt atatattaaa tgaggattcg atctaatgac aagacagcct
    10021 tattgctacc aataatgcag cttaccaaac aagggcaatc agtataaggg ttgctaacca
    10081 gctctgctga catagcctgc tttgagcgat caatactcct tctgattata gccaaagtca
    10141 gctaaatcaa gctttttgtc acgccagttt ttcttaacct tgacccaggt ctccagatag
    10201 accttatcgc ctagcattag ctcaatatca cgccttgcca gcttaccgat ttttttgagc
    10261 atggcgcctt gttttccaat aataatgcct ttttggctgt cacgctctac catgatggta
    10321 actcggatat gcaccttgtc agtcacctca tcacgcttca tcgaatcgac cacaacagca
    10381 actgaatgag gcacctcctg ctgtgtcaag tgaagcacct tttcacgaac catctcagaa
    10441 acaagaaagc gctctgggtg atcagtgatt tgatcctctg ggaaatactg gaagccctct
    10501 tcaaggttat cctttaagag ctgaacgagc gtttcgacgt tgtttccttg aagtgctgaa
    10561 ataggaacaa tttccttaaa gtccatctga ctacggaaat catcaatctg ctccaataat
    10621 tggtctgggt gaaccttgtc aattttgttg atcaccaaaa taaccggaat acgagcagcc
    10681 ttgaggcgtt cgataatcat atcatcaccc ttaccacgct tttcatcagc aggcaccata
    10741 aaaagaaccg tctcaacctc acgcagggta ctataggctg attccaccat aaaatcacct
    10801 aaggctgtct taggcttatg aatgcctggc gtgtcaataa aaacaatttg ctctgtctct
    10861 gtggtataga ttcccataat tttattacgg gttgtctgcg ccttatcgct cataacggcg
    10921 attttttgtc ccatgacatg attcaaaaac gttgatttgc cgacatttgg tcggccaaga
    10981 atggcaacaa agcctgattt aaacataagc tactaagggc ctaaaggatc agtcaaggta
    11041 agaatcaagc agcaggctat tcacctgatt gctttcctaa agcttatact cctttcctgc
    11101 gctgcactat cgcacaggat agcccatttc ctttcatttt tttaatggca taacattcgc
    11161 caaattttgg gaacaaagat aatcagcccc gtcaaaacag catagcctga aatgaccagg
    11221 acagcacctg cagccatatc cttggcatgc ttagccagca tggagaaatg gtaatcactt
    11281 gccaagtcaa ccacattttc aatagctgaa ttgacaatct ctaaggtaat caccaaaaaa
    11341 atagccagca ataaaaacag ccattctata gcagaaatac caaaaacaat cccagccaaa
    11401 gaggctaaca gggctgacaa aagatgactt cttaggttac gctcctcctt aaaggctgtc
    11461 agaacccctg tcaaagcaaa ttctaagctg gcaattactg ttctgttttt ccatttgcgt
    11521 ttattattgt cttgtgaggc cataagcagt caaaatctct tcctgtaacg taaacatctc
    11581 tttttcttcc tcaggagtgt aatgatcata accattaata tgcaaaaaac catgaacagc
    11641 caagaagccc atctcacgct caaaggaatg cccataggct tctgcctgct catgggcttt
    11701 gtcaacagaa ataaacagct ccccaatata agcatcaaac tcctgtatca tacctgccaa
    11761 gtcaggatca agctccaaat cctcttggct aaaggcgatc ggaagctctg gcttgtactc
    11821 cagagaaatc acatcagtcg gacgatcagt atcacgatat tcaagattca aggcgtggct
    11881 tctatcattg gtcacaaagg taaccgccat ttccttgtcc tctttaccaa ttgttttggc
    11941 agcaaaattg agcaaatcaa tggtttgctc catcatctct tgagaaacct gcttagtttc
    12001 atcaatcatc tctatataca tcattatatg aagaggtcct agcaagacag gtccaaacaa
    12061 acaccacact gctaggtcaa aaagcttgat acctcttatc ctttcaacat catttcagta
    12121 ctttctttcc attataccac aagaaaaaag aaaaagcagg cattagtcta gcctgctcca
    12181 aaagaagccg gaataatgac aagatcgttg ataccccagc agctgctgtt tctggaatac
    12241 ccagagcctg ctgcgcagaa tacagtcctc ttagatagct gggactccta ggattacaat
    12301 agtagataag cctttagacc acttccatcg cctaaaaact aatcctaaac ggctttccct
    12361 tagataccac tagctgctct caaagctatt gtggaggtaa cgatctggct tattggctga
    12421 cgccagtgat ttctgcttgt cataatcttc tttggttaaa taatagtgca gcactgtcac
    12481 aaaacggttg gaatcaaggt gatcacgctt agcatatggc tcttcatgtg aaaagcacat
    12541 gccgctttta gccataacac gtcccaaagc cggattggct ttatcatgct tagcaatcac
    12601 acaattcatg cctaaagctt caaaacacaa gaccagtaca gccttgacag cctctgtcgc
    12661 atagcctctt ccccagtgat gcttatgaag acaatagcca atctcagctc tacctaaatc
    12721 cagctgtata tgatgaagat caagcgtccc aataaagtct cctgtttcct ttaacacaat
    12781 cccccaccgt ccaagtggac tagccagata gacagaagca atgacttgac gggtctcctc
    12841 aattgtctga ttggctggaa agctatacct gacagtctct tcatcagaag cataatcaaa
    12901 catggctttg gcatcatcca aggtcactgg acgcaggcat agacgctctg tctcaagata
    12961 cctatgctct gctagttttt caaaaaagct tgccactact actctccctt tcctaaaaat
    13021 ctaactcacc taacagcatg actgcctgcc ctagccgcgt aaaatctgcc tcaccttatc
    13081 ctttaaaaca ggaaccagct cctcttcaaa ccaagcattt ttagccaacc aaagctgatt
    13141 tctaggagat gggtgaacaa ggggaaaata atccggaaga tagtcctcaa aatgctgcac
    13201 cgtttcggta agattgcgtc tacaaccttc accaaggtaa tattgctggg catactgtcc
    13261 gaccagcacc accaattcaa cctgaggcat caaggccatt aacggaccat gccacttggc
    13321 agcaaagccc tttcgcggtg gtaaatcacc tgattttccc ttaccgggat aataaaaatc
    13381 cataggaaga acgccaaaca agcccgactg ataaaaggtc ctgtcatcaa cacccagcca
    13441 agctctcaag cgaactccgc tacgatcatt ccagtacaga cgcgtctcct gagctacaat
    13501 accaggcgcc tgaccaacaa tgactatccg agcggtctga ggagctgcat aaagtggttc
    13561 gatacctttt ttggtatagt cacgattggc aggatcagcc ataatcgctt gcaatagctc
    13621 tgtcatgata ccctcacttt cataaaaggc tcttcaggtg aagagctctt ttttacgatt
    13681 tgtcttcttt aggcagctct ccaatgacct cataggttgt taagcctgac gtagactgac
    13741 ccgtctctgt tttaggccga tctggagcct tagtctgatg ttgcagctga ttagggctgc
    13801 tttttaatga ctctgctttt gaacctacag tttcataggc cttaataatc tcagcaacaa
    13861 cagggtgacg caccacgtcc ttggctgaaa aatgcacaaa atcaatctgc ttgatggcct
    13921 gcaatttttg agctgcatca atcaagcctg atgtgatatg acgcggcaaa tcaatctgac
    13981 taatgtcccc attaacaatc attttagact gaaaaccaag tctggttaaa aacatcttca
    14041 tctgcatgat ggtcgtgttt tgcgcctcat ctaaaatcac aaaggcatca tctaaggtcc
    14101 gaccacgcat ataagccaag ggagcaatct caataatatc acgctccatt aaccgagtag
    14161 tctgctcttt accaagaatc tgataaaggg catcgtagac tggtctaagg taaggatcaa
    14221 ccttttcctt caaatcccct ggtaaaaagc ctaagctttc tcctgcttca acagctgggc
    14281 gtgtgagaat gatccgctta acctgaccac gctttaaagc agtaactgct agcgtaactg
    14341 ctaaaaaggt ctttcctgtt ccagccggac caataccaaa taccacatca tgatgcttga
    14401 tactatcaac ataggccttt tgccctagcg tcttaacacg aattggcttg ctataaaagt
    14461 ccttgataat ctcttcctca taaagagcaa caaattgatc aagcctatct gaatccgcca
    14521 tagacagcgc agtcaccaca tcagaggtat tgataaccat gccacgcccc accaaaacta
    14581 aaagggcttg tatcgtcaaa cgcgctagct caacagcccg ctcatcatca ccaataatct
    14641 gaactcgctc agttctagca tgaatcacaa cattgaggtg agattctatc atcttcaaat
    14701 ggcgctcatt gctaccaaaa agagctaaca gatcatctgg gtgattcaag ctaatgtcag
    14761 tcgaataatg caaatttgtc ttccttttcc atctataagt aactctatta taacaaattt
    14821 tgctataaat cgggaataag acccagcttt aaagcctaaa agagctagcc tatggctagt
    14881 ggctaaggta atcctcccaa atctggtcaa actgccccag attgaatgaa aagctcgctt
    14941 cctcttcaag gtaacgactg atggtctcaa aatcatctgt atgctttgga aaggtcgggt
    15001 cctcaaaaac caaatcagct aataaagcag caggcttatt agatgtcgag ttgcgctgag
    15061 ccatcagcca agtgtaaaac gcctttctca ttgccaatgc tcctccaaaa attgatgacg
    15121 aatagcacta ctttgtgcat aacgctctgg attcttttga taaaagccct gatgatagtc
    15181 ctctgctaga taaaaaggct ctgccggttc aatgcttgtc acaatgggct ggtcaaagcg
    15241 ccctgaggcc tgcagggtct gcttggaccg ctctgcaatt tcccgctgcc gctcatcagt
    15301 atagtaaatc accggccgat agttgtctcc tctatcctca aattgcccaa aggcatcggt
    15361 cgggtctgtc tgagcccagt aaagctctac caaatctgaa tagctgatca gactcggatc
    15421 aaagataatc tcaacagctt cagtatggcc tgtcgtcttt gagcaaacct gctcatagct
    15481 tggattgtga acatgccctc ctgtgtagcc acttctcact gataaaatac ctgcctgctc
    15541 ctcaaaaggc tgcaccatac accaaaaaca gcctcctgca aaaattgctc tttccatacc
    15601 taatctccac tttctttgtc cttacattag tgattttcat tgtaacaaaa aaccttgcca
    15661 gaggcaaagc ttaatataaa acaagtcaca gactcaaagt aacaagactc ctcagcccaa
    15721 ctagtgccta gcactaagca gtactgtcaa gcagccacta ctagatcaag agggccacac
    15781 agagcttttt cgacaacaaa aatgattggc gctttaaaac aggctatcag ctaagctcca
    15841 cactcaaaat aaggaagcta gctatactga taaaggataa gtcttagcaa caccgatcca
    15901 gcttatgatt ataggctaag agacagacag ctccctatga tatcagctca gttcctgtca
    15961 cgtcctgctt gatcttgtta gccttcatca aaccacctaa ggccttttta aattgaccct
    16021 tggaaatccc aaaggttgcc ttgatatcct ctgggcttga cttatcatta agagtcatgt
    16081 agccaccatt agacttgaga taggtcagaa tcatctgggc atcgttttcc agcatttcaa
    16141 aggaacgcgg ctttagcgaa aggttgaggg tacggtcacg ttctctaaag ccaatcaccc
    16201 gagcggtcaa aacctgcccc aaacgaggct ccgtataacg ctcgctaggg tggataaagc
    16261 ccagcatatt attttctggc aggtaaacaa aggtccctga tagcttcaag cgatagacaa
    16321 tagcaggcag gctttgattt tgcatgttat cataggctgg actagcaagc ctttgaaata
    16381 tctctggctc agctggcaaa ccccagatac gatctttttt gtcaaccaca agcttaagat
    16441 aaagcctgtc tcctttttta ggccaaagat cctttagctc cggcaaaaca tctaaggaaa
    16501 ccacaatctc cttatctgga ataccagtat caacaaacac cccaagatca cgacggacag
    16561 tggtcacctc gccccagcca taatgatcac gccttgcgtc aataggcttc gtggtcaagc
    16621 gtagtctttg cttcatatct gtatagacaa agcccttaac catatctcct aatctatgac
    16681 tgccttcctc cttagctaga gcaaagctca gcccctcctt ttggacaaga taaaactgac
    16741 tattttcttc ttttactaag ccagtgataa ctgttgctaa taaatgattc atatcttttt
    16801 gttctttctt ttaaaaaata gggacaagtc caaagcagct gctttttagc cttgtcacct
    16861 atcctgttat gcctgatgtg tattaggtta cgcagctgat ctagcttaat gatcagataa
    16921 gccgcttaaa ctgaaagtaa ttccttttct ttgtcagcag tcattcggtc aatctctttg
    16981 acagcctcat ctgttgcttt ttgaatatcc ttttccaagg cttttaactc atcttcagtg
    17041 atttccttag ccttctcctg ctttttagcc tcgtccatag catcacgacg aatattgcga
    17101 atcgaaacct tcgcagtctc accaaccttt ttcacttcct tggctaattc cttacgtgtt
    17161 tcttctgtaa gcgctggaat aaccaagcgg atgacagagc catcgttagc tggtgtaatg
    17221 cccaaatcag aagcattcaa ggcacgctca atatccttga ttgatgattt gtcaaatggt
    17281 gaaatcaaaa gcacacgcgc ctctggtact gtaatagaag ccaattggtt caacggcgtt
    17341 ggtgcaccat aataatccac ctgaatacga tccaaaaggc tagcattagc acgacctgca
    17401 cgaatgcttg catactcgcg tgctagtgag tgatgtgact gtgtaaaacg ttctttcgca
    17461 gtttcaataa ttgcatttgc catgattgtt tttctcctta atcctttagc tctaaaatcc
    17521 taatcgcagg ccttatttga taccgttgtg ccaatatgct ctccaaagac cacacgcttg
    17581 atatttcctg cttcattcat attaaagaca accaaatcaa tatcattatc cattgacaag
    17641 gttgaagctg tcgcgtccat aatcttgaga ccgcgcttga taacctcccc atgagtcaat
    17701 tcatcaaact taacagcgtt tgcgtccttt cttgggtcag cattgtagac accatcaaca
    17761 ccatttttag ccatcaagat agcatctgcc tcaatctcag cagcacgtaa ggccgctgtc
    17821 gtatctgttg aaaaataagg tgacccaata ccagcaccga aaacaacaat gcgccccttt
    17881 tccagatgac gaagcgcacg acctcgaata taaggctctg caacgttttg catgggaata
    17941 gctgtctgca cacgagtatc aacgccataa tgctgaaggc tatcagccat tactagagca
    18001 ttcataacgg ttccaagcat gcctgtgtaa tcagcctgca cacgatccat accagcctct
    18061 gcagcaggct caccgcgcca gagattacca ccaccaataa caagagcaat ttcaacacct
    18121 gaattgtgaa cttctgcgat ctctttagca atcgactgaa ccgttgttat gtcaatgcca
    18181 acacccttat caccagccaa ggcctcgcca gacaatttga ttaaaatacg ttgatattta
    18241 ggtttcacta tttatgatct ccttattttg tccctaccat tctaccacaa aacaaaaaaa
    18301 tttaatagac caatgcaaga gaggaaagcg aaatttttga cgatcctttt atcaagatcc
    18361 ctttgagcag caaaaaagat gagtcattat aaaaagagca ttatcgtatc cgaatagcac
    18421 agttataacc tattaatacg acaaaaacca gaacaactat gacaaaaaac gccgtaaaaa
    18481 agacttaaaa tcaagcctca agccagacta gattctaagt cgtgctatat tgagagatga
    18541 tttgttttag ttatctagcc caatgccgcc acaagaagtc tgaggctcct tatctctgac
    18601 agcaactagc ctcccctgct ccagcagcag aacacgatga caaatggcct gacagatatt
    18661 agcatcatgc gcaataaaaa tataagtcag ttgatactcc tgctttaact catagagcaa
    18721 gtccaatagc tgcccttggg taatagggtc caagccactc aaagcctcat caaaaatgat
    18781 cacctccggc cttaacaaaa gagctctcgc tatacaaaca cgctgtagct gaccaccact
    18841 cagctctctg gcctttttac ccagatgagt ggcgtcaaga ccgaccgcag ctagtatttg
    18901 aacaacctcc tctaaggcaa agtccttaga aagggcctct gtcaatatct cttgaatagt
    18961 aaagagggga ttgactgatc ttagcgcatc ctgaaagaca agtaaaatcc gaggtccaca
    19021 tacttttaca gaatagggct gaccatgaaa gagcacctga ccagctgtcg gctgctctag
    19081 cccaatgatt aacctagcaa gcgttgtctt gccactacca ctttctccca taatcccaag
    19141 gctctcaccc ttttccattt gaaaatgaca atctgttagc actggctttt gatgaaagct
    19201 cttataaaca tgtctaaact ctatcatagc gtatcagccg atcataatga ttttgcaaaa
    19261 gcaactcctt ggtggcagcc tgacttggcc gatgaaaaat cgactcaaca cttccctgtt
    19321 cgatgatttt tcccttactc atcaccagta gttgccctcc caaagtctgt gccaattggt
    19381 aatcatgcgt cactgtaata atggtttttc ccttgtcctg caataacttc agcatccgta
    19441 tgatattaga acgattggca tcatctaaag cagaggtagg ctcatctaaa atgataatct
    19501 gtgggtctaa gcacaacaaa atagctagca ttacccgctg tagcatacca ccacttagct
    19561 caaaggggta cttcctcagc agctcctctg gctgctctag atagagctct cgcatgaaag
    19621 gcagagccct ttttagacag gccctttttg aaagtctctc atggcttcgg atggtttcaa
    19681 ggagatgagc ctcaatggtc tgaaagggat tgaacatcgc cataggattt tggaccatat
    19741 aggccatgtg gcgccctcta atgctctgcc attgcttagc atctaattga tctagtctca
    19801 tatcttgaca ggtaatcctc cctgtcatct gtacattcga cgggcattga ccaattaata
    19861 gcttagtcaa gagggtcttg cccgaaccac tcctgccaac aatcaccaag gagctcccca
    19921 agggcaactc aagattgagc ttacttaata gcacatcaga gccattataa gccgataaat
    19981 cattaacaat taaccgttcc atgttttcct ccacccctta gcatcagcgt aatcacctag
    20041 gctgttaaaa gctagcacag tcactaaaat ggcaagccct ggtgacatca tgagccacag
    20101 agctgtccta aaatagctcc ttgcatcatg cagcatcatt ccccattctg tcacattggg
    20161 ctgaacaccg atacccaaaa aagaaaagct tgagatcatg agaataatat tgccaatatt
    20221 catcaaagcc aacactacaa tcggccgata aacaaatggc aggatatgct tttttaagat
    20281 atgccgcaca gataagccca ttgtctgcgc actaatgaca tatggctctg ccttagcgct
    20341 tttgaccatc gtgaccatca gcctagcata atacagccac tctaccagaa caatagctag
    20401 gatcatgttg cctatgccct gcccaagtat ccccattgta gctagcgata gtaaaaagct
    20461 aggaaaggca gaaacaacat cagctagcca cagaaaagct gcctcgagcc ttccttgata
    20521 ccagcctaca accaaaccaa ccacagcacc aatagatagc tctaacaaac taatagtaac
    20581 cgccaaaagc aaggaatact tagccccata taacaagcgc gacagcacat ctcttcccaa
    20641 ttggtcagtt cctaataagt gctgctgact aggtggcatg agcttactag caacatcaac
    20701 agcatgagga tcaaagggag caagataagg agcaaacaag acacagataa acaacagcaa
    20761 tagcataaca gctgaaccaa ttacgtattt gggcatgctt cctcctttgt cttgcgcaga
    20821 cgagggtcaa taaaagacac tagctcttga gttatcacat ggtgtagtaa aaacaaagca
    20881 ccaaataaga gcatacaggc ctgaataacc ggaatatctg ctgctttcag actcataaca
    20941 aatagactgc caataccatt ccatgagaaa atatcctcaa caataataga gcccgtcatc
    21001 aaataaacaa aggtcaagct caagcctgtt gcaatagcag gaaaggcatt tctaatcagg
    21061 tgatgcttaa caatataata ggtcttaacc cctcttagcc tggcattttc aacatgcaga
    21121 ctcgttagct gctcactgat tgcctttcgt atcaaggcag tatattgccc aatcaaggaa
    21181 aagctaagcg taatactcgg caaaatgagg ctgctggcac ccgccttgcc tgacacaggc
    21241 aggagattta gcttaacaga aaaggctata atcaagagat agcccaacca aaagctaggc
    21301 attgacacag cgacaaagct gaataaacgc accagccgat caaacaagga atgctcaaac
    21361 aaaccactgc ctacccccaa aggaaaggca atcacaagta ccagtaaaaa agaggtcaag
    21421 cttagcatta gcgttgctaa aaagcgctcc accaccaaag gcaggacagg gacctttaac
    21481 acgtaagagg tcccaaaatt tcctacaaga atgtcagata accaggtcac atactgctcc
    21541 cataaaggct tgtctaagcc caaatagagc ctagcattgt gaagagcttc tggtgtaata
    21601 ctgatcttag ataggcgcaa atactgctct gccgggttag cggaggatag cttaaccaga
    21661 acaaaggtca ctatcgaaat cattagcaag gcgccaaagg tagaaataag cttcttcatc
    21721 atattttctc tcaacccttc actaagacat cagacaagaa ttgtcaggat agtcactcac
    21781 aaccagttcc tctgctctat caattcttga ctgccttatc agcagcactt ttttcaatgt
    21841 aacgcaatgg aagggcattt tcctctggtg caaagcgcat tgtcttaaaa tctcccttgc
    21901 gatatactga aacaactgac tgataggtga gtggaatata aacagcctca tcatgcaaca
    21961 atgacaatac ctgcttatag cccttgtcta ccttatcccc atctggctca atcaaaacag
    22021 atttaatcag gcgatcaatc tcagcctttg atggcaaact ctccaaggca atattttctg
    22081 ggtgaccatg atccgctttt gccgttaagg ctgtcatcca agcatgagga tcccaaggag
    22141 ctccccatga ataggtcagc atcatatcaa actgccctgt cttggcatta gcccagtagt
    22201 catcctcctc catagctgtc aagaccacat caatcccaag ctttttccac tcgccttgga
    22261 aatattcaac caaatccttg tctgtcgctt tagttgaaat ataaggcacc tgtaaacgca
    22321 actgctgacc atctttttcc ctaatccctt cttggttttc cttccagcca gcggctgtca
    22381 gcatgtcctt agccttttgg agattgtatt cataaggaac taagcccgca tcagcatgcg
    22441 gtgttgtttt tgaaaaaatg gtatctgctg ctgtctctgt tcctctaaag gtgtgcttag
    22501 caatagcctt tttgtcaacc gcatggttca ttgcctgacg aacccgcttg tcctgaaaca
    22561 ctgactgctt agcatttaac agcaataaac gagtcgacat gggctgagaa acatcagtaa
    22621 catacttctt gtccttagca tactgcacaa aggtatcaag actaatcaga ccatttccat
    22681 agatcaaatc aatatcccca gcctcaaatg ctaaggctct tgtctcagca tcaggcataa
    22741 tcttgatggt tacttccttt agctttggtt tttctcccca atagctctca tgacgtgtaa
    22801 aggtaatgta ctcatttgcc tttttctctt taacaaccca ttgacctgta ccaatcggct
    22861 ttttaacatt gtgcttattg gtgtcatcgc catcaggaaa accagcatca gccaaaaacc
    22921 taatcggtct gatcattgac aaatcataca aggtagcgct ataagcctcc tttagcttaa
    22981 tctcaaaggt atgatcatct aaagccttgt agctatccaa ttgattggta aagtgaaacc
    23041 aattatgatt gcccttattc tgctcagaga aaatcgaatc aaaattccgt ttaacatttt
    23101 gagcattaaa atcagaacca tctgaaaatt tagcctgtct caggttaaag gtataggttt
    23161 tgccatctgg gctaatcgtc cagctctctg ctaacgccgg ctcaatatta cccttgtcac
    23221 catatcgaac caagccctca taaaccatgt cttgaataac aaactgatca ggattgtagc
    23281 gatgaggatt gacatcacca aaatcctcac cccaagcaat cctcaactga tccgtacggt
    23341 aagaggcctg cttagcattt tgacaggccg tcagcagcaa agcaaaaaag aataacaata
    23401 gcacattcaa tttagttttc attatgtcat taactttcta aagatattaa tctatctaat
    23461 tttagatgtg gtttatcaca aaattaagta tggttaattt aatcatttta tagccctctt
    23521 gtcaagaaaa aatgagacaa aatcagccta gaaaaagcca gaaggctaca aataagcaaa
    23581 tcgtcaaaat catgaacact tcaggcttgc tgaggaatat tttctaatgg ttattagaaa
    23641 taatgaacaa ttacctaaca aaagactcca aaataaaggt aaaagacgaa cattcacctt
    23701 gctgctcagc taccaagaca aacaatcctg atagcatcaa ttttctttag gctcttagca
    23761 attagttgca atatcagata attttgaatt taattaaaaa aaacgaaact acggagacca
    23821 attatcagaa agctattcac agccagcaaa gggcatgcta aagtattatc tggaaaaaga
    23881 aaggcttagg aatgattatt tctaaactaa aaggagagag acaatgaaaa aaacaatgaa
    23941 gaagatgcta gcagcctcga cgctctgtat catcatgtca ggcagcttca tcagcggctc
    24001 agctagagtg ttagcggagg aatattatgg gtggaatgat gtcactgggt ctaagtcacc
    24061 atttcctcta tacgtgacac caaaaaatgg agataaaaat ataaaagttc aacaaacggt
    24121 tgtttactgt tttaacaggg atgggcaatg gccagaaaat tgggaaaaac ggatatatga
    24181 atctcctgat aaagttccac ataaattacc cgaatataat aaaaagtcag gaagcgataa
    24241 tctgtttcaa ttacttaatc ccaaaattaa gataaaaaat ccaatggcag ctttattagc
    24301 ggttttggaa gatggatatc ctacgtcatc ttcttcagga gtaaatcaaa gaacaactca
    24361 gctagctatt tggcatttta cagatggatt aagcaatctt gcccaatttc atcttactcc
    24421 ggaagaaact tcagcttata acaagttgat agaaaaaggg acaaatgctt ctaatcaaag
    24481 tgaaaataaa ctattaaata aaactttaga tatttattcc tatatagatg ggactggtga
    24541 taagaaacac aattatcaac accttcttgg ctccactcca attcctattg ataattctaa
    24601 agaaaataaa tgtcaatgta caaaagttga cttaatgcga actggagatg gggttaaaat
    24661 cattgtttat gttgataaca acggaaataa tagatatgac aacggcgaca aaatgctaaa
    24721 agaagaaact atcaaacatg gtcaacgcgg acctgctggt gaatctggga aaccagggcc
    24781 taaaggggat cgaggagaaa ctggagcacg cgggccagct gggcctcagg gcaaacctgg
    24841 gaaacaagga cctagaggtg ataaaggaga aaccggagaa cggggacctc aaggggaaaa
    24901 aggtgaacct ggaactcctg gtcctaaagg agaagacggt aaagacgggg ctcctgggcg
    24961 tgacggacaa ccggggccta agggtgaaaa aggtgaccct ggaaaagacg gacaagatgg
    25021 aaaaccaggg gaaaaaggag aacctggaat tcctggtcct aaaggagaag acggtaaaga
    25081 tggggctcct gggcgtgacg gacaaccggg gcctaagggt gaaaaaggtg accctggaaa
    25141 agacggacaa gatggaaaac cagggaaaaa aggtgaccct ggacgcgatg gtaaagatgg
    25201 agaaaaaggc gaacgcggtg aacaagggcc taaaggagaa cgcggtgagc agggacctca
    25261 aggagagcgt ggggagcaag gacctcgtgg ggaaaatcat actcctaccc cagacccaat
    25321 gcctgagccg gcacctaaac cagaatccaa acctgaacct aagccgacac ctcaaccaga
    25381 ggttaagcct ctgccagaga ctaaacctca aaaaccaacc aagccgtcag caatggctag
    25441 ccaaccaagt agcaaagcac taccaaaaac aaatgacact agcggcttaa tgactgtact
    25501 tggaacaggc ttgctctctc ttcttggatt aggcttcctg gcaaaacgca aaagaaagca
    25561 ataactaaca cataatcatt agtaatccat tcattatcca tttacaagtt atcataaaaa
    25621 agccttatca ttccttgact ggtatgataa ggctttttgt ttaccctata tagctctacc
    25681 cttactccaa aaatcactta accctaggaa aaggctgact atcatttttg gccaaaaaaa
    25741 gacagacacc aattcatgat gtctgtctca aaaccaatcc cttttagggt cagtccttaa
    25801 ttacttatta aaatgaactt ggatctacct tgatacccac accttgtgta gttgtgatag
    25861 atacgttagt catgtaagta ccctttgcag tagctggctt agccttaacc attacctcat
    25921 ggaaagcctt aaagttttca accaacttgt cagcgtcaaa tgatacttta ccaatgatag
    25981 cttgtacgtt acctgcttta tcagcacgat aggtaatttt accaccctta gactcttcaa
    26041 ccgccttagc aacgtccatt gttactgtac cagttttagg gtttggcatc aagttacgag
    26101 gtccaaggac acgtccaaga cgtccaacaa tagccatcat atctggtgtt gcaataacaa
    26161 catcaaaatc aagccagccg ccattgatct tagcaacaag gtcatcttca ccaacgaagt
    26221 ctgcaccagc tgcctttgct tcttcagctt ttgctccacg agcaaaaaca aggacacgct
    26281 gagttttacc agttccgttt ggcaacacca tcgcaccacg aatttgttgg tctgccttgc
    26341 gaacgtcgat gtttaagtta taagcaactt ctacagaagc gtcaaatttt gcgaagttag
    26401 tttcttttgc gagtgctaca gcttcctcta cactgtatgc ctttgtgctg tccacttttt
    26461 caagtgctgc acgcatttgt ttgctttttt tagccatttt tatcttctcc ttgtaatgtg
    26521 gtcatatcga tttgatttaa aaatctccca cgtcactcat ctctatgatg aagtcttgcg
    26581 ggtaataagg gcaggttgct gattaatcag taacggtgaa tcccatagaa cgagcagtac
    26641 cttcaatcat acgcattgca gcttcaatgt ttgcagcgtt taaatctggc atcttagttt
    26701 cagcaatttc ttgtacttgt gcacgagtaa ctgtcgcaac tttagttttg ttaggtgtac
    26761 ctgatccttt ttcaacacct gcagccttct ttaaaagaac agcagctggt ggtgtctttg
    26821 tgatgaaatc aaatgatttg tcttcgtaaa ctgagataac aaccgggata atcataccag
    26881 cctgatcagc tgtacgagca ttaaattcct tagtgaatcc catgatgttg atacctgctt
    26941 gaccaagagc tggtccaact ggtggagctg gtgtcgcttt accagcaggg atttgaagtt
    27001 ttacaagttt ttcgactttt ttagccattt ttaaaaatcc tcctgttgtg gttttggcgg
    27061 taattcacga tttttacctc ccacaggtat gctagagcat accttaccat tataccttat
    27121 tagacagata aatcaagtca ttttcacaaa aatgttaccg caaatagcag atgtctccta
    27181 tggcactagc agtacaagca tgtgaggctt ccaaggagcc gcttctagtt gacttttaag
    27241 cgttttttta ttataacaaa gctatgcata agaaagttac gatcaaagat gtcgcacgcg
    27301 aggcgggagt ttctgtggct actgtctcct atgtcatcaa taacagagaa gatcaaaaaa
    27361 ttagccctga aacgcgcaat aaagtgctgc aaatgattaa tcttttaaat tatcggccaa
    27421 accaagccgc aaaatcactc gtgacacaaa aaagacagct aatcgccctt tactacaaag
    27481 agcacagctc tgttttaaaa agagcagagc agcttcactt tatcacccag ctatctgcct
    27541 ttctttacac aaagcactat cacttgattt gccttaatca agaatacatc ggaaaatatg
    27601 atgtagcaga tgtcattctc accctagagg tcaccaaaga ggaattttac aagatcggaa
    27661 atagcaactt tgttcctttg attgctattg atagtattat tgatgatccc ttatttttcc
    27721 agattaatag tgaccctcat ctcctgttca ataaagccag tgcttatttt gcaggggagc
    27781 cctttgaact ggttagcctg cctattcaaa accaagaaat cactcaagga ctcgctcaac
    27841 agtttgataa catttgctgg attcactcta tttgcgacat cgaaagcgtg tctaagggga
    27901 atattctagt tattgatgat actgtcaatc atattcttag taagcacaag aacaaactat
    27961 acctgccaag tatctcagaa gctaagcttc tgaagctttt tcaggctatt gagtgggctt
    28021 ccaaaagaga agcaatcaac aatcataata ttttggttta accatgataa gagcttagca
    28081 acaagcttgc tgctaagctc tttttgttgg tcaagaggcc aactttattt aggtatcagt
    28141 cagtgtgcca gctcttttag ccactaaaag caggaattag tttacaagtc taccaattgg
    28201 gtataaaata gacttatgat catctacaaa ttaacagcct tagcctttat tatcctgact
    28261 cccttattct ctatgataat gatatcccta ttgagactgg gacgaagagg ccttaaattt
    28321 cctgatttag ccttaccact ttttgttttt gaaattgtta ttgtatcagg aaaatttttc
    28381 acccatcatt tactacctta ttacctgatt gttatgtcct tgttggccat tgttatggca
    28441 ctcttactga ttatcagaat ccagcagttt tcttaccgcc gatttttcaa actattttgg
    28501 cgagtaggct ttttagtcac actactcttt tacctgatgc tagttggtct tatttttatc
    28561 gtttagtgcc ttaccagaca tggcttcaag cctagcagtc tgaatctgcc aattaactct
    28621 agcactatca ctcaaaagga agctgtcttt gaactttctg cttgagtggg acttttttca
    28681 aagcaatcaa tccatatcaa accagcatta gagcatgcgg cttgatacgg attgattgct
    28741 ttaagaactg ttgtaaaata tcaaaaattc agtttttaat aaagtccatt agctatttct
    28801 acactaaata tcatttaaga aaacagaggc taataactag agttcactat aacctaaaat
    28861 caccaatacc tccgattaac ttaatttaac caaactactg tatataccaa agttttttac
    28921 gtgtcattat aatacgttca gataaatcat ctaatgcacg atctttgttg agaccaacat
    28981 catattgaat acccattaat ctatctagaa actcaagacg atatttcttc ataatatttc
    29041 gtgagtgtcc ttctggaaaa tgctcatcaa taagcgaact tacaatctca actttattac
    29101 taattttaaa atagcgactt ttcaaagatt gtaattcttc tttaattgct cttaatttag
    29161 aaaaactatc tgctccataa accttagctt ccatttcatt agcctcagaa taacttagtt
    29221 ttattgttgc aataaaattt ctaagtactt ccttctcttt tttaagctcc ctttctgtcg
    29281 gactcattct atagtaatat tgacgccaac gatattgaga agcgttgact ttttgatcac
    29341 ttatagtcaa aatagtcaat gctactacac taaagaaaaa tattcttttc gtttgcagtt
    29401 tctcctatac ttcataatgt actatttgta tataaacaca acataaccaa gcattagtat
    29461 atcagaaaac tttcttaaat atgtgatatt agctaatctt tttttaaaac tctctatata
    29521 ttaaggtatt atggacatat tgacttagca gattagatct gccaattagc tctagcacta
    29581 tcactcaaaa tgaagctgtc tttgagtttt ctgcttgagt gggacttttt caaagcagca
    29641 tatcaaaaac ccgtatcaag ccacatggtt aagcttagct tggtacgggt ttgttttatg
    29701 atgagccttt agatgagctc ttttttaatt ggtttgcagt acctttcttg gcttagtccc
    29761 ctcagctgga ccaatgacac cggcctcttc taattcgtcc attagtcgag ttgctcggtt
    29821 aaagccaacc gatagacgcc tttggagcat cgaggcgctt gccttttgcg tttccaatac
    29881 aagagccttt gcttcctcaa aaaggggatc accctcagga gctccgctgc tgccataatc
    29941 agagtcacta acctcacccg gatcaaaata atcatcataa tcagcctctg cctgctcctt
    30001 gataaagcta acaatgcgct caacatcatc atctgaaata aaggagcctt gcagacgcac
    30061 agggtgattc tcatcaatcg gcttaaagag catgtccccg cgaccaagca gcttttcagc
    30121 gccattttca tcaagaatgg tgcgactatc tgttcctgat gaaaccgcaa aggcaatacg
    30181 tgatggaaca ttagccttaa tcaatccaga aataacatca acagaaggtc tctgagtagc
    30241 taaaatcata tggatacctg ctgcacgcgc cttttgccca agacgaataa tagcatcctc
    30301 aacctcctta ctagccacca tcatcaaatc agctagctca tcaacaataa caacaatcat
    30361 cggcaaaggg atttgctttt gctcagattg cttgttgtag gcttcaacct tggcattgta
    30421 gcctgcaata tttcggacac cgaccttact gaacagctca tagcgatttt ccatctcatc
    30481 aacaaccttc tgaagcgctt tgcttgcttt acgagggttg gtgaccaccg ggattaacag
    30541 gtgaggaatg tcattataaa cagacagctc aaccattttc ggatcgacca ttaggaattt
    30601 gacctgatcc ggtctagcct tcattaaaat actggagata ataccgttga ctgcaacaga
    30661 tttccctgat cctgttgagc cagccaccag caaatgaggc atgcgggtca aatcaaagct
    30721 tctggcacta ccgttgacag ccttaccaag aggaatttcc aataatttgt catcagatgt
    30781 gttggattgc tcccaaagct cgcggaaaga aaccgttgca acctctgaat ttggtacctc
    30841 tatacccaca agggatttgc cagggatcgg agcttcaatc cgtacgtcct tggctgccaa
    30901 ggccaaggcc aagtcatcag ctaaattgga aatgcgattc acacgaacac caacagccgg
    30961 cttaacctcg tatttagtta cagatggccc aatctctgcc cgctccacct tgacgtcaat
    31021 tccaaagctt ctgaaggtat cctctaatac cttgatattt tgacgaacaa ggtacttttc
    31081 cttgaattga tttttaggct tatcagcagc aaacagctct atcgtcggca gcttgtaaag
    31141 cagattggtc tttggcgtga aatcgacctc cactgacagc tcctcatcat ctgacagcgg
    31201 cgcctctcct gcgattgctg aagcacccgt tagaggggct tctggtacag actcctcttc
    31261 atctccaaat gcctcaggct catcatcagc agggtgtgag tcataggcca gaatttccgg
    31321 ctcaaaaaat gcttcagact ccttctgatc agccatctcc atcaataggt cttctggctc
    31381 tgctaaaagc tcacctgtct caggattaat cgcttgattg gccagatatt cttgctcctc
    31441 caaggcctct cttgctagac gctcctcttc agccagcaat cgttgctttt ctcgctcaac
    31501 aaaccgcttt tccttgtttt cttgataggc cagggatagc ttttcaaaaa gcgtcttaac
    31561 aaaatgactg acgtcataaa tatcccaagg ggtcattaaa aacaagccca gcaggataaa
    31621 caaaaaacca ataaaataag agccaatatt agaaaacaag aaggaaatag gcttgtacag
    31681 catggcccca agcataccac caccaacaaa ctcgctaacc ttaaaggcta gcaggtcatt
    31741 ggtgattagc tggatagtcc cagcaacaat agcctgatga gctagctgag gcaatgagaa
    31801 aagataggca tgccattcaa ccagaagccc taaaaacaag atgataaagc cagcgataag
    31861 gccatctttt tgcctgagcc acttgaagaa aaagaggtaa aaaaggaccg ccaacatcaa
    31921 gagattggct aagtcgccaa ccataaagcg aataagatta tataaggtaa ccccaagcgc
    31981 acctaagcga agcatggcaa aaacaagcaa taaagcgcag gagaaagaag caatcattct
    32041 cttaatagcc ttttgctttt caagctctgc ctttgttaaa cgtctcttag ggggattttt
    32101 ttgtcgttga gttcttctag ccatagcctt attataacat tttttaatcg ttatgaaaga
    32161 tgacattaaa attctcaata aatagatgaa gctgcttgat tttatgctat aatgtcaatc
    32221 ataagaacaa ataggagttg aagatggaaa aagaatttaa caccttgacc tatggtaagc
    32281 ttcccctgca aattgatatg gggcatggca agctaattcc caaaggagtt gaagtcaagg
    32341 ctatcgttga tatgcagacc gggcaagtca ccttcaaggt ttctcaggag gacttagaga
    32401 agcttagaaa tagttaaaaa atagacttcg tctcaatgcc ctttagcttt attttccaag
    32461 tcattttatg ttaaaataaa agaaattgtt ctaaggagta cacatgaaaa aactactatc
    32521 ttttggctta atcggtcttg ctttgcttag cttaagtggc tgtgagtcca ttgatcgtgc
    32581 tattaaaggt gatgaatacg tcgatgaaaa aatcgctaga gaggaaagcg agacagcagc
    32641 aaaggcttat gaagcaaaaa tcaaaaaagc actcaaggct gacgctgatc agtttccaca
    32701 attaaataaa gaagtcgaca aagacgaagc taaggtcatt atcaaaacta atcagggcga
    32761 tatcaccctc aagctcttcc ccaagtatgc accgcttgct gttgaaaact ttttaacaca
    32821 cgccaaggaa ggctattacg acaaactttt gttccatcgg gtgattaata actttatgat
    32881 tcaaaccggt gatccaaagg gagatggatc tggcggagaa tccatttgga agggcaagga
    32941 cagcaaaaaa gatgcgggac aaggctttgc taatgaaatc tcaccatttt tatataacat
    33001 tcgaggggct cttgctatgg caaatgccgg tgcagatact aatggcagcc agttcttcat
    33061 caatcaaagc aagctcaacc aagccaaggc cttatcaatt gataattact ctaagccaat
    33121 cattgactcc tacgaagaag ggggtaatcc tagcctagat ggtggctata ccgtttttgg
    33181 tcaggttatt gagggtatgg atatcgttga taaaatagct gccagcccag tcggcccaaa
    33241 tgacaaacca atagagaaca tcactattaa tgctattgac attgttaagg attactcctt
    33301 taaaaaatag cctctaagct acaacaacaa taaaacgacc agctccttat cggaaaagcc
    33361 accgattcaa gagctggtcg tgattttttg ctatcaatta aataaagaag ctagcctatt
    33421 gatcatatca ttagcagcta tccattcaca gccagctatg gtttactagg aatgcttttt
    33481 aaagtagccc tgcttaggcg aaacaaagaa gctaatcaga aacaccacag ccgaggtcaa
    33541 aacaatgctt gagcctgctg caatattaaa ggtgtagccc aaatagagcc ccaacacaga
    33601 ggtcatagct cccaagcatg aggagataac cagcattacc tttaggctgt tagcatacaa
    33661 atacgctgta gccgctggcg taatcagcat cgccacaatc aaaatggtac caacactttg
    33721 catagcagtc accgaaacca aggtcaacaa aatcatcaac agataatgat aagcagtgac
    33781 cttcattccc atagaccttg ctagcacagg atcaaaggag gtaatgagta attccttaaa
    33841 gaagaggaca ataatagcca aaacaaaaac cgaaacaatg atcgtaatcc atttgtcact
    33901 gtcttgcact gctaggatat ttccaaagag gatatgaaaa agatccgttg agctattagc
    33961 aatcccaatc agaataaccc ctaaggcaag aaaagagcta aaggttatcc ctattgctgt
    34021 gtctcccttg ataacagagt tttccttgat gtaggtaatg ataacagagg ctagcaagcc
    34081 aaagacaata gcccctacaa aaaaattaat ccctaaaata aaggacaagg ctactcctgg
    34141 caaaacagcg tgagaaatcg catcacccat taatgacatg gacctaagga taataaagca
    34201 gcctactgct cctgatacaa taccaataac aacggctgta ataagggcat tttgtaaaaa
    34261 atgataggac atcaggccct caaaaaactt caaatacatt taaaacattc cctttcctaa
    34321 gaatagatga tcaccatagg cctttgatag ggtttcaaca gtgaacacct catcaacaga
    34381 tccataagcg atcagctctt tgttcaatac cactaactca tcaaagtaat gctctacctt
    34441 gcttaaatcg tgatgaacaa ttaaaatcgt tttgcctgct tttttcaagt ccttgagcag
    34501 gtcaatgatg attttttcac taaccgaatc aatcccaaca aagggctcat caagaaaaat
    34561 atagtctgac tcctgaatca agcatctagc tactagcata cgctgaaact gaccaccaga
    34621 aagagatttt atcggacgat taccaaagcc agcaagccca acctgctcta gcagctggtc
    34681 aacctgatca tattcttttt ttccgacacg acgaaaaagc cctagcctag tgtaggtccc
    34741 taatgagacg cactccttca ccgtaattgg aaagttgtag tcaatcatgc tgcgctgctc
    34801 tacataagca atcgtatgcc ccagccttcg accgtccttt tgatcaacag ttacttggcc
    34861 actataatct aaaagattga gcatagcctt catcaaggtt gattttcctg caccatttgg
    34921 cccgataatc ccaacgatag ctggtccttt gatttgtagt gagatattgt ctaaggcttt
    34981 tacgttaccg ttatagctaa ccgaaagatt ttgcgtatca atcatttttt ctccttaata
    35041 caaacaaagc acaacaccag aagctgctgt gctttattgt tatattattt tgctaagcct
    35101 tcagaaattt tatcaaggtt ccatttcatc atggcatagt agctgtctcc atcttggcct
    35161 tttttggcta cagagtcagt aaagatttct gcatagatcg gaataccact gtccttagaa
    35221 acagtctcca ttggacgtct gtcaacactt gactcaacaa aaagcgctga tggcttaacg
    35281 tctttcaatt tttcgatcaa tgatgaaatt tgatccggag ttccttcttc ttcagtgttg
    35341 atttcccaga tgtaggctga tgggacaccg taagcttttg agaagtattt gaagcagcct
    35401 tcacttgtga cgattagctt tttattgtca gcaatagcat caaattttga ttttgcttcc
    35461 ttatcaagct tctctagctt ctcaacgtaa gcttttaggt tgttttcata ggtttccttg
    35521 tttttagggt ctttagcgat caattgcttt gcaatatttt ttgaatagat aaccccattt
    35581 tcaagattca accaagcatg agggtcttcc ttgccttttt cactttcacc ttctaggtaa
    35641 atcacatcaa taccatcaga tacagcgaag tagtccttgt ccttttcctt cttagcattt
    35701 tttacaagct ttgtaaacca agcctgtccg ccgtcttcaa ggttaatacc gttatagaga
    35761 ataagatcgg cattgctggt cttctcaacg tcttctggca atggctcata ctcatgcgga
    35821 tcttgaccaa tcggcacaat gctgtgcaag tcaatcttgt cacctgcaat atttttagtc
    35881 atgtcagcaa taatggaatt ggtaaccaca accttgagct tgtcactctt agcttccttg
    35941 tttccaccat tagagcaggc aaccagcatg aaaacagcca aaaaagcact caaggcgagg
    36001 ctaagtttct ttttcatcag ttatctcctt aggatctatt atttaattaa ttaagtatag
    36061 ttaattatgc tattagcata actttttttt aggcctttgt caagattttt atgaaataat
    36121 ctgatataat aatcattata aataagagaa aggcttttag acatgacgcc taataaagaa
    36181 gactatttga aatgtattta tgaaatcgga gagcaaaaca ttaaaatttc taacaaaatg
    36241 gttgcagaga gaatgaaggt ttctgcaccc gctgtgtcag aaatgattaa gaaaatgatc
    36301 gcacaaggct ggattgtaaa ggataagacc tgcggctatt atctaacaga gcaagggcag
    36361 cgcttagtgg caaatcttta tcgtaagcac cgattgatgg aggttttctt gatccatcaa
    36421 ctgggctata ctgctagaga ggtgcaccaa gaggctgagg tactagagca tactgtgtca
    36481 gatatgttta ttgatcgctt ggataaaacc cttggctatc ctactttttg ccctcatgga
    36541 gggacaattc cacgccgcca gcagccacta atcgaaatca acaaaacaac gcttaatact
    36601 attaaagagc tgggaatttt tcgtttgagc agggtgcatg atcactttga gcttatccag
    36661 tacctagaag cacaccagct gacgatcaat agtgagttta gactgattca aatagatgac
    36721 ttcgcaaaaa cctataccat cacttatgca gataaggaat tgatcattcc tgaaaacatc
    36781 gccaagcagc tctttgttac tgctatttaa ataaaaaaag acctgatatt tgctgtcacc
    36841 acaggctatc aggttttttt ggtcatcatt ttttatcagg taaggcctct aaaaaggcta
    36901 tcaagacctt ggctgatttt tttccagcct caacaataaa ctgatcgaag gtcatattag
    36961 catcgtgggc cgctgtgtca ctcatcgccc taacaacaat aaatggcttg ccagcagctt
    37021 gagctgcctg tgccactgct gctccctcca tttccactgc taaggtctct gggaaatgtg
    37081 ctttgatggt atcaatactg tcttggccgg caataaagct atctcctgtt gcaatcaggc
    37141 caatccgact attggtcttt tcctgatcaa gcacctgctt aaaggtctca accagcttgc
    37201 tatcactgtc aaagtaaagg ggctgcgcag ccatttgacc atagtcatag ccaaaggccg
    37261 tcacgtccac atcatgatac accaagcgat cagcaacaac aacatcacca atagccaagc
    37321 cactagctat tgctccagcc gatcctgtat ttataatagc gtcagcctga aaatgctctg
    37381 ctagcatcgc aactgtcatc gctgacatga cctttccaac accagattgg actaagacga
    37441 gctcatggcg accaagacga cctgtatagt aggtattgga aagcacctga tgctcttgac
    37501 tatcgtggag ctgctccaat aaaaaccgca gctcctcttc catagccgca ataattccaa
    37561 ttttcatatg atatccttat ttgttttttt ctataaatta aagaccgcat aaaccaagag
    37621 agcaatcaag acaagcaccg ctaagagaat cagatttaac cgcgattgaa agcgactgcg
    37681 ctttgcattt tcaattctgc gacttttgta aatacgatca gtatgcttat cctcaaaggt
    37741 catgattttg gtttcaaaat ctgcataatc gtcaggctca aactgttctc cgcgctgagc
    37801 cttttcgata atgtcatcag tcagcaaggg cttgcccatt acacatcacc tccaaaatga
    37861 agggcgtaat attgcagggc aatgatggtt ttagcatcga caagctttcc ttgtgccact
    37921 agatccatac attcttgata gctcagctca agaagctcaa tcacctcatc tgcgtcctgt
    37981 ggtctaggat tggcaactct ctgcaggtct gtcgccaagt acagcttaat tttttcatta
    38041 caaaaaccaa tcgctgtata aaactcgtga ataagacgca aatcaccaga ataggcggtt
    38101 tcttcctcca gctctcgtgc tgctgcttct aatgctgagt tggcctcacc gacctctagt
    38161 tttccagcag gaatttcata agaaatcgct tcgatagcct tacggtactg cttgacaatt
    38221 aacagcttac gctctggcgt tacagccaat atagcgactg caccgcgatg aaaaatcaat
    38281 tcgcgcttag cctgacctag gccgtttggc aattggacat catctaccgc aactttgaaa
    38341 atgtgaccat caaaaatctc ttgcctttta atcgtttttt cttcaaaatc catgtctgat
    38401 ctccttgctt tctctccatc attttacttt gcttgatttg ggtgatgtgg cagcctcttg
    38461 gcatagcc
//
LOCUS       DARYXZ010000018        38461 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYXZ010000018 DARYXZ010000000
VERSION     DARYXZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38461
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(297..2087)
                     /locus_tag="TV186_000809"
     CDS             complement(297..2087)
                     /locus_tag="TV186_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL1532222.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
     gene            complement(2202..3005)
                     /locus_tag="TV186_000810"
     CDS             complement(2202..3005)
                     /locus_tag="TV186_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1532223.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            complement(3269..4108)
                     /locus_tag="TV186_000811"
     CDS             complement(3269..4108)
                     /locus_tag="TV186_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1532224.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            complement(4124..5218)
                     /locus_tag="TV186_000812"
     CDS             complement(4124..5218)
                     /locus_tag="TV186_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL1532225.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            complement(5480..6877)
                     /gene="uxaC"
                     /locus_tag="TV186_000813"
     CDS             complement(5480..6877)
                     /gene="uxaC"
                     /locus_tag="TV186_000813"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL1532226.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            complement(6905..7522)
                     /gene="eda"
                     /locus_tag="TV186_000814"
     CDS             complement(6905..7522)
                     /gene="eda"
                     /locus_tag="TV186_000814"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1532227.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            complement(7705..8376)
                     /locus_tag="TV186_000815"
     CDS             complement(7705..8376)
                     /locus_tag="TV186_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL1532228.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            complement(8418..10208)
                     /gene="uidA"
                     /locus_tag="TV186_000816"
     CDS             complement(8418..10208)
                     /gene="uidA"
                     /locus_tag="TV186_000816"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL1532229.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            complement(10229..11257)
                     /locus_tag="TV186_000817"
     CDS             complement(10229..11257)
                     /locus_tag="TV186_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1532230.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            complement(11341..12885)
                     /locus_tag="TV186_000818"
     CDS             complement(11341..12885)
                     /locus_tag="TV186_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1532231.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            complement(13300..14559)
                     /locus_tag="TV186_000819"
     CDS             complement(13300..14559)
                     /locus_tag="TV186_000819"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1532232.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(14875..16080)
                     /locus_tag="TV186_000820"
     CDS             complement(14875..16080)
                     /locus_tag="TV186_000820"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1532233.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(16413..18632)
                     /locus_tag="TV186_000821"
     CDS             complement(16413..18632)
                     /locus_tag="TV186_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1532234.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            19159..20100
                     /locus_tag="TV186_000822"
     CDS             19159..20100
                     /locus_tag="TV186_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL1532235.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(20075..20278)
                     /locus_tag="TV186_000823"
     CDS             complement(20075..20278)
                     /locus_tag="TV186_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL1532236.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(20659..22335)
                     /gene="dnaX"
                     /locus_tag="TV186_000824"
     CDS             complement(20659..22335)
                     /gene="dnaX"
                     /locus_tag="TV186_000824"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL1532237.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(22335..22832)
                     /locus_tag="TV186_000825"
     CDS             complement(22335..22832)
                     /locus_tag="TV186_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL1532238.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            23012..23782
                     /locus_tag="TV186_000826"
     CDS             23012..23782
                     /locus_tag="TV186_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL1532239.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(23964..24236)
                     /locus_tag="TV186_000827"
     CDS             complement(23964..24236)
                     /locus_tag="TV186_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL1532240.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(24259..24885)
                     /gene="udk"
                     /locus_tag="TV186_000828"
     CDS             complement(24259..24885)
                     /gene="udk"
                     /locus_tag="TV186_000828"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL1532241.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            24981..26075
                     /locus_tag="TV186_000829"
     CDS             24981..26075
                     /locus_tag="TV186_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1532242.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(26340..27626)
                     /locus_tag="TV186_000830"
     CDS             complement(26340..27626)
                     /locus_tag="TV186_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1532243.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            28048..29211
                     /locus_tag="TV186_000831"
     CDS             28048..29211
                     /locus_tag="TV186_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1532244.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(29334..31952)
                     /gene="alaS"
                     /locus_tag="TV186_000832"
     CDS             complement(29334..31952)
                     /gene="alaS"
                     /locus_tag="TV186_000832"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL1532245.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(32308..33309)
                     /gene="prsA"
                     /locus_tag="TV186_000833"
     CDS             complement(32308..33309)
                     /gene="prsA"
                     /locus_tag="TV186_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL1532246.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(33372..34079)
                     /locus_tag="TV186_000834"
     CDS             complement(33372..34079)
                     /locus_tag="TV186_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL1532247.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(34162..34800)
                     /locus_tag="TV186_000835"
     CDS             complement(34162..34800)
                     /locus_tag="TV186_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1532248.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(34850..35482)
                     /locus_tag="TV186_000836"
     CDS             complement(34850..35482)
                     /locus_tag="TV186_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1532249.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(35472..36029)
                     /locus_tag="TV186_000837"
     CDS             complement(35472..36029)
                     /locus_tag="TV186_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1532250.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(36228..38030)
                     /gene="pepF"
                     /locus_tag="TV186_000838"
     CDS             complement(36228..38030)
                     /gene="pepF"
                     /locus_tag="TV186_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1532251.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(38020..>38461)
                     /locus_tag="TV186_000839"
     CDS             complement(38020..>38461)
                     /locus_tag="TV186_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1532252.1"
                     /translation="IHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMDK
                     HLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHED
                     LSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT        11220 a         9103 c         7292 g        10846 t
ORIGIN      
        1 aaaaacatta tctgttcaat tgtttcactt atcaacaagc ttatagcttg tctatcatct
       61 gaagcaaggt tgagcattag gcacaaaaag aaaagctaga atgaccctct agcttttctt
      121 taggattaac aggctctatc atctccatat cggataaaac tccccaccac agggattatg
      181 gggctatttc tgcagctaca aggggctgat taacaggttt tatcctgaaa tctttttaaa
      241 tcattcagag caatcaccgc agaacacgta aagcctctac ttatcctgta gcaacctcag
      301 aagctatgcc atagctgggt atcaatcaag ccacaaaagg catcaacagg agacactcca
      361 gtgaattcag attcaccagc taattttgca accaaagcct tcatagtgtt gtccttgcca
      421 tcgtaggcat taatataagt accaacctgt ggcatatcag caagggcaaa ggcatgctga
      481 actgaaacaa cgattgttgg gacctcatgg acgtagaatg gctgatccgg tgttccctta
      541 gcagctggcc agataatacg ctgaactgta cctccagaat tgacgtccac caaattaaga
      601 attaaatcat aatgctctgt aatgtttgaa atcggctgct tttgtgcata aacattagca
      661 atagccgctg cacgctcttc ctctggtagc tgcatgattc gctcttcggt tgattcccag
      721 acagttacct catgcccacg cgcctctagc aattccttga caatgtctga ggcccgtttc
      781 ttctgtcctg caatcatagc accaaagcca cccttatagc cctccacgtt aacaatcagc
      841 acacgcttgt agcgctctgg agttaccggg aaaatccctg cctgcttgtt tttcacaagg
      901 gtaatggcct tgtcggcaac ctcatctgca attgcttgag cctctggtgt gttaatcaag
      961 accatcgcct tgtccttagg cagcataata tcttctcggt gtccttcaaa gcgatgaagt
     1021 ccaagctttg ctttcaagcc aagcgtacga cgaagggcgt catgaaggcg ttcgtcactt
     1081 aaaattcctg cctcatagcc ctctttcatc cattgtaggt cttcatctgg gtcattaaag
     1141 aataaaaaga gatcgcagcc tgcctcaatc gctgttggta acaataagcg acgtggcatt
     1201 gaggctgtca tcgcaaccat atgcgaagcg tcagtcacaa tagcaccatt atagccaagc
     1261 tcaccacgca gcagctcatc taagagggtt ttattaagtg aggctggaag catatcatct
     1321 agctcacgct cagggtgcat ggccttttca acatttggca ggtgaatatg tcctgccata
     1381 ataccaggta agccagcctc tgcaagctcg ccataaatac gtccaaagct agatagccac
     1441 tcctccttgg tcattgggtt tgaggcaaag gacaaatgat ggtcacgctc atcaatacca
     1501 tcaccaggga agtgcttggc aaagggcatg ataccatatt ccataatccc cttcatatac
     1561 tctttggaaa gctcaatgat ttgatcaaca tttacccccc agttgcgatt agcaatgatt
     1621 ggattacgcc aattacgcgt caaatcaaca attggcgcaa aggaggcatt acagccaaca
     1681 gctgacgctt ccagtcctgc aatccgtccc atttcataag cgtatttagg atcgtttgtc
     1741 gcagctacct tgatttcatc accaacctta gtgccatcat tgacagcacc atcaccacca
     1801 gcctctgtat tggcagcaat gagcattgga atcttggatt tggtttgtaa aatataattt
     1861 tgatcccaaa tttctgaagc catgccttta ttgtagcgaa cagctgcaat atgataatcc
     1921 tcaagcacct gagttaaata atcctctgat cgactagccc ccatattaac aaatagctga
     1981 cctatcttct cctccaaggt cattgctgca atggtatcct ccacccagca aatagcttct
     2041 tcgtctaggc tatatggttt ttttcttaaa tctactaaat gtgtcattgt acttcctttc
     2101 aactaaagcc ttctctgctt gcttttctgt tttaatgaat ggcgctacag caacctgcta
     2161 ccaagcccta acaggctcag ctccactggt cagctacctg cctacctatc aagattacgc
     2221 cagaaggctt ctgtaaggct cttgacatca agctctgtca agtcaccagt tgtaaaagct
     2281 tcagcagcat gtgacagatc ctgccacgag ctagcctcct taccaacgag gattggaaaa
     2341 aaagtgatct ggttttgctc agcagctgct agatcacctg gtgaatctcc tatcatcatc
     2401 atgcgctctc tcacatatcc ttcatcaatg agctgtgcta tgacagcctc ttttttgcca
     2461 cgatcctgac aatacaagcc atcaacatgt gtcatcaggc cttgatcctg ccattccttt
     2521 tgaacggcct ctttattagc tgagctgaca acaaaaacct ggccaagctg gtgcaaggcc
     2581 ttaagagcag ctaaagctcc tagaaatgcc aatgcctctc ctttgtaggc ctcaatctga
     2641 cggtttacct catttgacca gtccaaggcc ttttgcaggt catcactagg acgcttaaga
     2701 agctccgcct ccagagactg attggataat gaggcagtgt gttgtaccca ttgctttaaa
     2761 gcgtcaatcc ctgtaactcc tgcgtattct agccccataa caagcccaac aaagcggtta
     2821 acaccgcgtg tacgcgaata aagattaatg cgatcccact cttttaagaa agacgcttgg
     2881 tctgctaccg caaaataatc cgccgcaagc ggaccaaaaa agagctgatg cttataagtc
     2941 atggtgtcca ttgcgcagcc atctgagtcc acacaaaaga caaattgttc agttttagct
     3001 gtcattccaa cctccaaatc atctgatgaa ttaattctaa cacagtaaga aaacgctgtc
     3061 aatcataaat cctaatcaag cagcgtttca tttttaaaag ctatcattac ttgttgattg
     3121 ctaaaaaagg ctagagtgat aaggaacaat agaagccaca aatcatcata cctttattaa
     3181 tggcagcttg gctacaaagc aagctgtcac gatagaaaaa ccacttgagg cattgcagtt
     3241 tgagttctca agtggtttat tttttagctt agacgcctga ataagctgca aatccgccat
     3301 caattggcag aacaacgccg ttcacaaagg aagcagactg ctcatcagcc aagaaaaaga
     3361 ggcctccaat taattcttct gcctcaccaa agcgtcccat tggtgtattc ttaaggattt
     3421 tttcagcacg agccgttggc tgtccgtcct ctgtgaaaag gaggctacgg ttttgattgg
     3481 ttaccaaaaa tccaggagca atggcattac aacgaatgcc aaccttagaa aaatgaacag
     3541 ccaaccactg ggtaaagttg gaaatggctg ccttagcccc agaataggct gggatctttg
     3601 ttaatggcgt aaaggcattc attgaagaaa tgttaataat atttgccccc ttacgaccaa
     3661 ccatatcctg agcaaagact tgcgtcggca acaaggtgcc taaatagttt aaattaaaga
     3721 caaagctgat acctgcttca tcaaggtcaa agaaggtttt tgtatcctct ggcaggcttg
     3781 tgtcgtgaaa ctcattatcg gttgttgcct tagggctgtt tccgccagcg ccattcacta
     3841 aaatatctgc tggaccaaaa tctgctaaaa ctgcctgacg aacggcctct aggttttctt
     3901 tagacaatac atttgcctga taggcctttg caataccacc ctctgcctca atatcatcaa
     3961 caaaggcctg tgccgcctct tggttaaggt ctaacagtgc caccttagcc cctgcttttg
     4021 caaatgcctt tgccatactg ccacaaagga caccgccagc tcctgtgatc acaacaacct
     4081 tgtccttaaa ttcaataact cgactcatct catgcccctt tttctattta tctccaactg
     4141 tttttacagt aatgccaaaa tctggtatct ttccagctgc acgcatatta gcctcataaa
     4201 gcccattaaa ataggtcgca ccaagtgccc ggtcatacag cccatagcca ggggttttgg
     4261 tttgatctcc ccagatacga cgaccatgat ctggacgaag tggtccttgc cagtcataat
     4321 caaccaataa tttgataata gcattcatat caatgtcacc agcctgtgac aagtgagcgg
     4381 tttcttggaa gccccaatca ccagcagtga cattacgcgt atgcataaag ttaatacgct
     4441 ggcgcttaag cgcgtactcc gtcatagcga tcacatcatt ttgaggatca gaagcatagg
     4501 agcccacaca catggtaatc ccattattag gggaatcata aaggtctaag aagcgctcta
     4561 cagccttttg acctgttatg atacgtggta agccaaaaat accataagga ggatcatcag
     4621 ggtggatagc catcttaacg ccagctgcct ctgctgttgg cataatagcc ttaataaaat
     4681 aatctaaatt agcccacagg tcttcttcgg aaatatgatg acgataatgc tcaataatag
     4741 ccttcatctc ttcttttgag taagaaaaat cccaacccgg taggttcaaa tcatctgcca
     4801 caggatccac atctgccaag tctgccttta aaaaagcaag tgaggttgat ccatcaggca
     4861 atgggtaatt aagatctgag cgagtccaat caaacactgg cataaaatta tagcaaacca
     4921 caggaatacc tgccttacca acattgatga tagaggtctt ataattttca atcagctcat
     4981 cacgattggg ctttccttgc ttgatgtcct cgtgaacagg aattgattcg atgactgaaa
     5041 tctcaaggcc tgcagcctca actatcctct tcaattcaag gatattttct agtggccaag
     5101 cctgaccaac tggtacatca tacacagctg ttacaattcc ctgcatacca ggaatggcct
     5161 tgatttcctc taaacttact ggatcatgct ttccatacca gcgaaacgac attttcatag
     5221 tatcatacct cgagttctcg taaactcctt ttcctttcga ttcacacaat tgttatttat
     5281 tattgttttt ggggctaata cccttgcaac taaagggcct gggcctgcta cttggtctag
     5341 cctttgtaat ctagtcaatc aacaagacgc cgacagcagc tagcaggccg atattgtcct
     5401 agcctctttt aagactagga ccttaatcat agagcaacat catatttcta tgcttcttct
     5461 agttaacgac caaggcagcc tagttaaaat actggatagc attattgtag gcaatgtcct
     5521 gagccatttt accaagtgcc tgataatcct ctggtacctc accttcttca atccactcac
     5581 caaggtaggt cgacaaaata cgtctgaaat aatcatgacg ctgataggat aaaaatgaac
     5641 gtgaatccgt tagcatgccg acaaaattag ctaacaaacc ttgctcagcc aaggcattca
     5701 tctggctaat cataccaagc ttggtatcag caaaccacca gcctgcaccg aattgcagat
     5761 agcccgcaat accgttttca ttggcttgga aattagctag tgtattagca accgcgatat
     5821 tatagctcgg atttaggtta taccaaatca tctttggcag gctgtctctt tgcaccagat
     5881 gatccagcag gcgattcata ttgattgcta gtcctgtttg gtctcccagt gagtcaacac
     5941 ccacatctgc ccccagcttg ttgaatatag ctgaatgatt attgcgaaga gcaccaaaat
     6001 gcacctgagt aacaaagcca tagtgcttat aaagcctgca aagctctgca aacaccgctg
     6061 tctgccattg cttgacctct aacggctgcg gctgatagcc ctctaaaacc cttgtcatga
     6121 gacggtctaa ttgctctggc tctgctgctt caaagacaat ctctgtaaag ctgatgtcac
     6181 tggccttaca accattttct gcaaaatagg caatacgctc ttccatagcc gctataaagc
     6241 tcttaaaatc tgtaatagtt cttccggtag cttgagcaag acgagccaca aaatctgcaa
     6301 agcgctgatg ctcaataaaa gcctcatctg gtctaaaggt tggcgcgaca accgtctcaa
     6361 aggtatcatc agcagctaac ctcttatgcc aagctaggtc atcaagcggg tgatctgtcg
     6421 taccaataaa ccgcactcgg ctatctgcaa tcaactttct aggactaatc tggtgctcaa
     6481 ccaagtaagc attgatacga tgatagattt cctctgcatt atcctcagtc agtagctcac
     6541 agacaccaaa gacatttttc aactccatca ctgaccagtg gtaaacagga ttgccatagg
     6601 agcgctgaag tgtacgggca aaggccttga atttatccag cttagaggct gagcctgtga
     6661 tttcttcttc cgaaatgcca ttagcgcgca tcaagcgcca cttgtaatga tcaccaccaa
     6721 gccaaaggtc aacaatattg tcataaacct tgtcctcaaa aatttccttt ggatctaagt
     6781 gacaatggta atcaaaaata ggctgatcct tgatttgttg atagaggcgc tttgctgcct
     6841 cattttttag cataaaattg tcgtcattaa aagccatctc gtcctcctct tatgaccaat
     6901 tcccttaatc aagggctgat acaaatgacg ctgcaatacg ggttacacta tcatagccct
     6961 cagcctcaac tcggctagct aaggctgaac caatcccaac agcaacagca cctgcatttt
     7021 tccactcctt gacattgtca atcgacacac cacctgatgg catcaaatca acctcaggaa
     7081 taggaccatg aatatcctta ataaagcctg gtcctacaac acctccagga aagaccttaa
     7141 taatcggaca agaggcattc attgctgtga caatttcagt agctgttgca cagcctggga
     7201 aataaagatt tgatgcctga ttggcaacct ctgctatttc tctagaaaaa tgaggactaa
     7261 ctaaaaagct agcacctgct gcaatagctt ctcttgccag atcaggcgtc atcactgtcc
     7321 cagctccaat aatcacagca tcatcatgct caaactcagc tgacaatatt ctaataacct
     7381 ctgaagcatt tggagtagaa taggtaatct cgatattacg aataccgcct aaaatagcat
     7441 gcttagcaat ggcaatagcg tcttctactg tttttccacg aataatagca aaaaaataat
     7501 tctcttttaa tcggtttagc ataggctcct ccttttcatg aaaccgttgt cttagtttta
     7561 ttatataaat catcagatga tttgtcaagg aaaaagcaaa aaaaggactt ggttctagta
     7621 tctctaaaac caagccctct tattcgagcc aagaagcaaa tcactcaaaa ctcaatagac
     7681 tgtttccggc aagcaagctt aagcttatga tagaaaagcc gttcgcttaa ctgtcatgat
     7741 gtgcaggagc atagcgtcat gtgccgcgat cggatctccc gctttaatcg cattcagaat
     7801 atctctgtgg gcttgtagag aatcttcttt catctgacga tttgtgtaat tggcattgat
     7861 cagatgaatc gactgattga tcaccggtag caagctatcc atagcaatat tgccactgta
     7921 ttttgccatc aaggaatgga aattcacatc cagctgcaaa tgcttaggat caccagcagc
     7981 tacggcctct tcaatatcaa caacaagctt ctctaaggct tcaacctcct ttggcgttgc
     8041 atgctgtgct gtcaaagcgg caatcctagg ctcaagcaat agccgcaatt caaacaaatc
     8101 agcggtcagc ttggctgtgt ccttgactaa ggaaaagcct aaaggatcct cagaaacacc
     8161 ttttttcgag ctaatataag tacctgatcc ttgtctaacc tctaaaacat ttctagttgc
     8221 taagcttcta acagcttctc taatagtgct tcttccaacc tctaagtcct gtgctaactc
     8281 atattcattg gggagctttg ctccaacctc atacccacgt tctaaaatta gctttaacaa
     8341 gcgctctgct gttttttcga ctaaaggcct agccatacaa tcccttcttc ctacttattg
     8401 ctagctacta ttgtacacta tttcttttta taattgtagt ggggaatggt attccagcgc
     8461 tctttaaaca aaccaacaac atgcttaggc tggcgatttc tagaaaaaag ccccttatga
     8521 ttgccttgaa tacggaagat catcagatta gtttcaaaat cagcaaaatt ccatacctgc
     8581 tctccaacta gattaggaat ctcatcaaaa acgcggtgac tcatctcata gaagcggcac
     8641 tgaaattcct ctgtatatgg aatatcccac atcgaatgaa gaccaggaag cgtatctgca
     8701 ccgtactctg tcatcaggat aggcttgtta ggaaacttct tctgccattc taatagctcc
     8761 tgacgcagcc caacctctcc tttgatcaag tctccatgat caacatacca agcataataa
     8821 cggtttaagg agatcacatc aaccagatcc atcaccttat ctcgatcagg tgttgctaat
     8881 agcagattaa ccaatgttac tggacgctgc tgcggatcta gtgccttata aagagcaatc
     8941 agcggctcaa agtattcgtg tgctccctct tcatggctgg caggctcatt ggccacgacc
     9001 cacatgacaa cagaagggtg atttttgtca cgcttgacga gctcacgaat tgcttgctca
     9061 tgcgcttcct tagttttcat gacagaccaa gtgccattgt cctttggcga aagatccaag
     9121 gaggctgtaa agttttggaa gagccctact gccggaacct catcaataac caagattccc
     9181 atacgatctg ccagacgcat catctcctca gagtaagggt agtgtgaggt acgaaatgaa
     9241 ttggcaccaa gctccttgag cagattcata tccattaaat tagctgcttc attcaatcca
     9301 cgaccgttga taaaggtatc ctcatgctta ccaaagccct tgaaataaac aggcttgcca
     9361 tttagtaaaa attgtccttt ttcaactgca atacttctga taccaaatgg ctcatcataa
     9421 ctatctacaa cattgccatc tacgatgatc tcaacgtggg cagtgtatag ataagcatct
     9481 aaaacttccc ataaacgaac cttatcaagt cttgccttgc catcaatagc ctgcgcaacg
     9541 agcttgtgct cttcatcaaa gatcgtcacc ttaacctcat caacagctgc tgaggtttca
     9601 acagatacct cgactaaggc tgatgtcata tcctcagaca agtcactcgt gatcgtgata
     9661 tctgagatat ggcattttgg ccgcaccata agcttcactg gacggtgaat accagcatag
     9721 ttgaagaagt caaaattctc cttgacaatt tttttgatac tgccatcctc ttgagtttct
     9781 tcactataat tgcccactgg aaggctggta taatctaaaa tattattggc acaaacagat
     9841 accttaattt gattatcctg ataatgggtc tcaggcacca acacctcaaa tggagtgaag
     9901 cctcccttgt gttgccctaa agcttgccca ttaacataga ctgttgcatt gtgcgtgaca
     9961 gagccaaagc gaagtaccag ctcctcatca gcagcaagat ctggcacatc aacaaagcgc
    10021 tcgtaccaaa aatcaccgat gtaattgcgc ttgtccttat ccacaaccac atcattaaag
    10081 gaggtcggca caaccatcag ctcatcagag gctaggagct cctgcgggtt atggtctcct
    10141 agcttaaatt gccagagccc ccctaaatca taaatctttc ttgtttttgt cagtattggg
    10201 tataacatac gatttctcct ttatcacatt atcgttgaat ctcatgcgat tccttggcca
    10261 gtaaatgatc aatgtcatct tgtgtcatga tattactatc accctcaatg gtatgcttaa
    10321 acttaaagct agccattgca acatctaaag tagcctgctc gtctttataa cttaataagc
    10381 catgaatcag ccctgccgta aaagcatcgc ccgtccctac tcggtccaga acctgaatac
    10441 cagatttttg ggttttataa aggctgccat tttgatacag gtaggccttt aacaggtatt
    10501 cattggtata gtccatctct ctctgggtaa aggcaaagca ttttacccca taggtatcag
    10561 ctaacctagc cagcacctcc ttcaacaagg cttcatcatc atagggtcta ttcaagccta
    10621 attgatcctt taaatcaagc gcgccgcttc ccttaagcgt cagcggctca atgccaatac
    10681 aaacatcagc cagctgaaca agaggcgaca agagatctct agcctcctga aaggaggacc
    10741 atagactagc cctaaaattc aaatcaaagg aaatagtcaa tccctctgcc ctagcctttg
    10801 tcatcaaata ataggtcagc tcataaagat cactcgttag agcaggcgtt atcccagaca
    10861 catgaaacca atcagcctca tcaaaaacat gctccaaatc atagtcagca cgctttgact
    10921 cccaaaaggc tgaatgacag cggtcatagg taacccgact tgctcgcaaa gaaaagccct
    10981 tttgataata ataaagccct aaacgctgac ccttttcgat aatatgctcc tgattaattt
    11041 gacgcgaaaa gagaaaggtt tttgtcattt gtcccagatc attgtctgga atagctgaaa
    11101 taagagagac ctgatgccct agctgagcaa ggcttgagat gacattaagc tcagaacctc
    11161 caaattgaca atctaggctt gttgcctgct ttaacgtctg gtattgaggg ggtgacaatc
    11221 gcaagaggat ttcacccaag gatacaactt ttttcacaac attcctcctt atactatcaa
    11281 gctactctat tattttataa aaaagtcagc cactcctcaa agaaatagct gacccagcac
    11341 ctaatcctta tcaacaggat attttgtcac atcaacatag tccatgtctg acagtggtac
    11401 atttttagcg atagcctgca cgcgttcctt atcagagctt gctttcatca cttgaatctt
    11461 ctcttgaata cgcaccattt cctctttgtc aagcttgtag aatgacatca aaatcaaagc
    11521 cactagtaag gctacaaatg gaataccgac atgcagcgca atcaaggcca tctttagact
    11581 tggggtaagc ggtgtctcaa tcgttgggta agtctttgaa aaaccaatac cagccagcac
    11641 tgcaccaata accattggcg caaatgatga tgcaatcgag tcagtcaagg agaagattgt
    11701 accaatcatt cctgagacat aacggcctga ttctgatgtt tcgtagtctg aaatatcagc
    11761 tcccattgtt agcaccaagc tagcaggcgc ttgtgaggca tagcgagcaa taatcagtgt
    11821 cacagtaaac aaaatagtgt aaaggttaat atgacttagg ctgagatccc ctttattacc
    11881 cataaagagc acaataccaa aggctaacaa gccaaccaag ccaatctgaa gagctctgat
    11941 atatgagaaa cgcaaacctc tcttacgagc aatacctgaa aaagcaatat taatcaaaat
    12001 ccccggaaca ataaacagca atgagaattg accagacaaa gcatagttac caaataaaac
    12061 accaaacaag ataaccatga caaccgaatc accaaagaat tgaacagcaa acttaaccaa
    12121 ggctgcggca attgatagga cctgtagcgg ctggttgccc ttgataacct tcaaatagtc
    12181 cttcagagct gtcttttgcg tattttcacc aagaccaaag aattcctttc tgtccttgct
    12241 ccaaatacca agcactgcca atagacccaa aatagctgag ataacaatcg tgccataaat
    12301 caacacgtgg aagaaggctg gtgtgaagtt accaaatttt ggaaccaaga agcttgacac
    12361 aacaaactgt ccaccagtca tcagcaaggt tgtcataatg gcatcaacaa tgttaaagat
    12421 tggacgctgc ttcggatcat tagtaagggc tgtctgacca gccttagtga tggtttgctg
    12481 catagagtag ccgatcttat ggataatcaa aaccagaata aaaagtggaa aacgaatgtt
    12541 ctcactaact ccacttagac caagcagcag aataagtgat agggctgtga taatatttcc
    12601 gatgattagg atcggacgat acttaccaaa cttagtttct gttttatcaa tcaagatacc
    12661 aatcgcagga tcaataaagc catcaaaaat acgaatataa cccatgatct ggctgacaaa
    12721 aatagctgcc aagcctagaa cacctgttga aaagtaggtc acaaacataa atgtgaatag
    12781 gtagatattg gttgaagcat tgtttaaagc aaataaaaca agctgccaaa ccttagcgcg
    12841 gttataggta acctcttcaa ccctttggtc aattgttttc tccatcagag aaatccccct
    12901 tttatcattc gcttattgtg taagcgtttt atttctacat gcttatctta ctattcatct
    12961 gatgatttgt caacacaatt taaacttttt tcgcctaatt ttaaaaaata aagcttattt
    13021 aggattttaa tcattaaatt catctgataa tttctggtgt ctttaaaaat aatcatcaga
    13081 caattactca ttgacatcaa aaaaactgag ccctgtgcaa tacagaacta aatcctttca
    13141 ctaatatgtc gtgtccaact tttgggggtc agtacacagg atagacaggg ggttcttaaa
    13201 aatcaaaagc ccctaaaacc actctcatac caagcagtct taggagctct aagcattcat
    13261 gtcaggtgat aatcattagg ctatgaaagc cttcagttct taatcctcaa taagctgaat
    13321 atcagcccct aaggctgtta gcttatcaat aatgttagca tagccacgta aaataaactc
    13381 aatattgcta atctcggttt taccctgagc cattagacct gcaatcacca aagcagcacc
    13441 agcccgcaaa tcagttgcct taacctgtgc cccactgagg cgattagagc catgataaac
    13501 aatttggctg ccaagaatgg caatatctgc tcccatacga gcaagctctg gcacatggtt
    13561 gacacgcttt tcatatatcg tatcaatgat actaccacga ccctcagtcc ttaaaagcag
    13621 aggagtcaaa ggctgctgta ggtcagtggc aaagcctgga tagggagagg ttttaatagt
    13681 gactgctttc aaggcttcct gcttttccac aaaaatagaa tcctcttcaa ccgtcattct
    13741 cacacccatt tcctctagct tagcaataaa gctctctaag tgctcgtaaa ggacattggt
    13801 aatccttacc ccactaccaa cagcggctgc caaggcaata taggtaccag cctcaatgcg
    13861 atctgggatc acctgatgtc tggtgccatg aagcctttca actccctcaa tcgtaatcac
    13921 atcagtacct gcaccacgaa tatgcgcccc catgttattt aacagtgtcg caacgtcaat
    13981 aatctcaggc tctctagctg cattttcaat aatggtctta ccctttgcct ttgtcgcagc
    14041 aatcatagta ttaatggtag cgcctacact gatagtatcc atgtagatat gagcgccatg
    14101 aagctgctga gcctctgtca tcaggtgcat gcttgctccc tcataagata tctgggcccc
    14161 cattgcttca aaagccttca gatgaagatc aataggccta gggcctaagt cacagccacc
    14221 cggcaagccc acaaccgcct gcccaaagcg tcccaataga ctgccataaa aatagtaaga
    14281 ggctcttagg ctgttaattt taccataagg cataggaata tcttgaaccc ctctggggtc
    14341 aatctccaag gtatccccct gataggtcac catagctccc atgagcttca tgatttcaat
    14401 aagactgtca acatcactaa tagctggtac cccatctaaa gtgacaacat cgtctgccaa
    14461 aataatcgca ggaatgagag ctacaacgct atttttagcg cctgaaactg ccacctctcc
    14521 ggataaggct tttccaccat taataataat ttttcgcata ctttcaaaac tttctgatac
    14581 tagaattcaa cctttttatt ttatcacaaa tagcggtcta ttacaatcac ctcatcacca
    14641 gctgctgcaa caggcttaac aacctgcctc ttgatcactt ttcataacag gtttttgaga
    14701 agccagactc ttatctggat ctttcttctg ctgcgcaggc ctttttgtct ttcatagccg
    14761 ccaagcctga caagttttgc tggactaaaa aagctcccaa ccagcagcac agccgctagc
    14821 tcaggagcta ttataccttt aagtcaatca tcaactaacc ggcgctcaat ctgcttaagc
    14881 accctctgac agtgctgcca ccgcttctgt caatggagat accttgtcca attgttccca
    14941 aggcaggtca atgtctgttc gccccatgtg cccataggct gctgtctgcc tatagattgg
    15001 acgcttgaga tcaagcatct taatgatccc tgctgggcgc aggtcaaaga cctgacgaac
    15061 agccgcttcc aaaatacttt ctgacactgt tgatgtccca aaggtatcca cacgaactga
    15121 aactggctgt gcaaccccga tagcataggc taattgaacc tctgctttac ttgcaagccc
    15181 tgctgccaca aggtttttgg caatataacg agctgcataa gaggctgagc ggtcaacctt
    15241 agttgcgtct ttaccagaga aggcaccacc accatgacgc gcatagccac cataggtgtc
    15301 aacaatgatc ttacgaccag tcaagccaga atctccctga ggaccaccaa taacaaaacg
    15361 cccagtcgga ttgataagga atcttgtctt ctcatctaga taatgggctg gaataacagc
    15421 cttaatcacc tgctcaatca tatcttgacg aatctggtca ttgcttactt ctggatcatg
    15481 ctgggttgat ataacaactg tatcaacacg aacaggctta tcatgttcat catattcgac
    15541 cgtaacctgt gatttagcgt ctggacgcaa atagctgatc tcacctgatt ttcgcagtgt
    15601 cgccaaacgg cgtacaagct ggtgagataa ggaaatcggc agtggcatta gttctggtgt
    15661 ctcatcaatt gcaaagccaa acattagccc ctgatcccca gcaccaatcg cattgaaatc
    15721 atcgctttgt ccttcacgtg cttcaagtgc ttcattaacg ccttgagcaa tatctggtga
    15781 ctgctcaacc agagatggat gaacacccac tgattctgct gaaaagccat attctgcctc
    15841 agtatagcca atctcagcga tggtatcacg aaccacacga ttaatatcca cataggcagt
    15901 tgttgaaatt tctccaaaaa cgtggaccga gcctgtgtaa acgcaggtct ctgcagcaac
    15961 gtgtgcctct ggatccttgg ctaaaatagc atctaaaata gcatctgaaa tttggtctgc
    16021 aatcttatct ggatgccctt cagatactga ttcagacgtg aaaagtttac gttctgacat
    16081 aaaaatgtcc ccccttaaaa agaatgatac ccaccagcac acatgccaga taggattttc
    16141 ctagcctcac tcatcaagcc agccgccaat acaaaaggac tgtatccaag ctagcctatg
    16201 actaacgctt agcgagttac aaagtaccgg cttttagact gctatcctca gataacaaag
    16261 ccgtcttatc gggacttaat aacttattta ttataccact tttagcggga tttgtaagag
    16321 ctccatcagc ttttttctca aaataagaaa aggaataccg ctacaggcgt attcctcctc
    16381 ttaatgtcgt gataatcagc gcaagctatc gattaaccat ggtggtgctc atcgtgatca
    16441 tgatgctcat ggtcatgctt atctgctgcc tcttgatcag tatcagccgg cttatgctcg
    16501 tcttcaacag cttctgctgg tgtggcatta tttagactac caccctctgc tgccttgaag
    16561 ttcttgataa ttccttgtgg gaattgtccg ctttcagcag ctagctcctc agctgggaag
    16621 tggttaccat cagcctgaat gtatttcagg gtttggttag gctccttcaa ggccaaggtg
    16681 ttaatcttgt tacgattaac attaattgct tctagggcga gataattgtt gacaccctca
    16741 aaattagtca gctggttctc ttcaaggtta agagactgta atgagctttg tgtacctggt
    16801 aaggccaagc tattaatcat gttctggtta gctgatagct gaatcaggct cttattgtgc
    16861 tcaagacctg tcaagctgtt aagcttgttt tggtcaacca ctagctgctc taatgccggt
    16921 agatccttga caaagctaag gctttgtaaa ttaacctcct tggcagtgat ttccttgaga
    16981 gcagaggatt ttaaggttga caaatcaagg tcagggttgt ttgacacaaa gagtttggtc
    17041 aattgtccct tgtttgacaa ggcactcaag tccttaatct gattgtgctc taggctgaca
    17101 gcgactagct tttgagcatt tgccaaggca gaaagatctg taatcttgtt aaagtcaagg
    17161 ttaacggact ctaggtttgg caattctttc aaaatagaaa tatctgtgat atcatttcct
    17221 gctgccgaaa ttaccttgta atgcggaaag gctttaagga agctcaaatc agaaacacca
    17281 ttttgagaaa tatcaattcc ttcaagcgtt ggcaggttct tcaagaaatc ataattttta
    17341 atgccggtct gtgtcatcca caattgtttg aggttcttga actggtagac tggggtaata
    17401 tcagtgattg gggtaaagcc aatacctaaa atctgtatat taggcatcag gtttaaacct
    17461 gcccgcttaa gaggatcctt aatctcaccg atattgaggt attcaacagt cgccaaccat
    17521 gccttcattt tctctaggtc tcgctctctt gatggaaact cagttggtgc atttgcatgg
    17581 ataatggacg aaatcacttc ctcatcaaag ccaagctttc tcagagttgc cataccgatt
    17641 ctatccttag catgcggatc tactgcatga ggatcaaaag gttttgataa atcaatatcg
    17701 tcaatatagg ttgcatgacg atggtcacca tgtggatagt caagaatgat accttcttct
    17761 gtatgctcca cacgaatgct gtcctcagga atatttaatg acttagccaa atatgctttt
    17821 ttcaaagcaa tcgttttctc aagatcactt tgtggcttag ctggtgcttc ttcctttggc
    17881 tgttcgatta aatgcttcca cttgctgtta cgcaagcttt cataagtgac taaatgattg
    17941 tggccattgt gatcaacaat caatccatat gatgttcgac cgacaatacc tgtcccgtca
    18001 aacaagaagc catcacttgt tgggtaatca acacctgcaa attttccaga cggtgatgat
    18061 ggagctgata gtggcacatg gttaggcact ggataagcta cctgaccacc tagtgagctt
    18121 tttaggatat agtggtaatg atcaccatga cggacaatat agcccaaggc gtcctcagct
    18181 acaatatcag ctgggttaaa cacatagtga tggtgcgggt cattagcact agtatggtga
    18241 tgacctgatg ctgccttggt ctgctcaggc ttgtttaggt cagcgtcctt tggaatcagg
    18301 tactcaaact tgctgccctt gagatctgca taaaaaataa aatgcgaatg cccattatgc
    18361 tcaacaacaa taccgttttc tgttctagat aagatttttg aatccttggt caagataaaa
    18421 ccgtcatcag ttggaaagtc aatccccgct actcccttac ggtcttttct tgtttgctta
    18481 acctttttag actgtttctt tttggtcgct tttttagctg tctgttttgt cttaggctga
    18541 tttgttggct gctttgtcga ctgacaagct gtcagggtca ggtgacaagc cataaacagg
    18601 ctagccatta gcattaattt tttacttttc atctttcctc cataaattaa ctggttaaat
    18661 aagatattaa ctagttaaat ataccaaaaa aacaaataat ttcaactgtt ttcttatttt
    18721 taattcattc tcattcaaca atcatagtag cttggctagg ttggcagaaa aatgagcctc
    18781 tcctactctc atcaaataaa cagatagcct taatgatggc tgagataaca gcatacaaag
    18841 tcgttaaagt cacttgtaag aaaaagaagg acatatctta ccaccactat cttgctcatc
    18901 aaagccctac ggctttcaga caaaatcttc ataacagcgg aaaggctgat gaagcagctc
    18961 agacaaaaag agcaagctcc ttaacgtcaa ggatcagaga tcagcacaaa aataacagca
    19021 ggctacatta agaactgcaa ttccttgaaa tagaattgct tttttacaaa aaaatcgtct
    19081 ccctagactg ttccatcatc tcacgtcatt tgtattattt gctcttgaaa tccagtcatt
    19141 ttatactata ctagaattat gaagacatct gaaaaaattt accaattact agcttgcagc
    19201 gacgactatg tcagtggaga atacttggca gagcagctca agctttctag aacctctgtc
    19261 tggaaatcca tcaaaagcct tgaaagtcaa ggccttcaca ttgaatccct caagcataag
    19321 ggctatcgcc ttattcaagg agatatattg ctgccagagc tcatcagcca agagctcaac
    19381 atgcctttat cttatcatga gaaaagccag tcaacacagc tagacgccaa gcaaggaatc
    19441 gagctaaagc atactgctcc taggctctat ctcgctccaa gtcagtatgc ggccaagggg
    19501 cggcttaatc gccaattctt tgcgtcacct catggcggca tttacatgtc cttgcatctc
    19561 aagccaaatg ttccttacgc agacatgcct ccttacacca tgatggtggc ctctagtatt
    19621 gttaaggcta tttcaagatt gaccggtatt gacacccaaa tcaaatgggt caatgatatt
    19681 taccttggcc ataaaaaaat cgccggtatc ctgactgagg ccattacctc tgtggaaaca
    19741 ggcgtcatta ctgatgtgat tattggcgta gggcttaact tttttgtaac cgaattttct
    19801 gaaaacctca aagaacgagc aggctctctt tttagcaaca agcctagtat tactcgaaat
    19861 gccctaatca ttgacatttg gaagctcttt accacaatac caatcaagga ccatattaag
    19921 gtctacaaag aaaaatcact tgtccttcaa aaacaagtga gcttccaaga aaatgatcgt
    19981 caaaaaacag caactgccat tgacctgact gatgaaggac acctcatcgt tcaattagac
    20041 aatggtcagc tacaggtctt aaggagcggc gaaattagtc tttcttcctg gggggattaa
    20101 cagcattaat gatgtttttg gtaaattggt caatagcata agcacgcctt aaatctctaa
    20161 agagcaaaag accccaaaac agagcaaaaa tataatcgcc tgaaaataat aaatcgctga
    20221 aaaaataagc ttcaaaggca caaatgaatg ccataaacat aaattgtcga atagtcatac
    20281 tactattata ccaagaaaac taaatttcca ctaacgattt tcacgcagct tgaagaaaaa
    20341 ggcagttagc ctgcttcaag cttttttgct gctctttgat agcctgtaac agtcaaataa
    20401 aaaagagctc actctaaaaa cgacgccaaa agccagcttg attgctaggc ttgtagtcaa
    20461 ttgtctcaaa tcagtgaatc actaagcctt ataagaactc agtcattggg tcacaatgac
    20521 acctagctct aagcagcaaa aaagagaacc acaccggtcc tctctagctt ggcttgtcag
    20581 ctatctatta gtgctgacaa tgagccctgt catctcctta ttctagacaa ttgatacact
    20641 accaatcatc agctagcgct aatcctctat gagatgaatc ttatcagtta aaaagtcaaa
    20701 cccctcaggc atgtcaaagg tcgcttgctc agactctttg gctgtctctt ttttggtttt
    20761 gatggtcatg gcaaactccg agcgaatatg gtggaagtct gcctttggta ctgccaagat
    20821 atgaggagaa aaccctgctg ccttactcat gatattccca aacatatcat tcaaatcctg
    20881 acgcttcatg gcctgctcag cgttaaaggc ggcctcaaag gccaaaatag cattttcact
    20941 attggctaaa acaggctccg agcctagtaa caaagctcga tcctgtgcag aaatactatc
    21001 taaaatctca ttccaagcac tttttagcgc ttctaaatat tgtcgtgact gctggctatc
    21061 ttgaacagtt tcctccatga ttttcaatat cttttcccga tcaaccttgt aggtaaaggc
    21121 ctttggcttg atggaatgag ctggtgtagc ctgcgcagtt agaccctttt gagcctgtag
    21181 ctgtgatatc gtctccctca gctgactaat ctcatgcttc aagtcatcaa catcagctag
    21241 caggctagac ggtatcgcag tgtctgctgc ttgtccttgc tctgccagct gaatggtcat
    21301 catttcagcg tagattctag gatgggttcc ttttttgatc tcaggcaaat gcttggttac
    21361 tgtagcaatc attgtaaaaa gctgatcaaa agacactgca aggttatcat caaaaagagc
    21421 tgactgcctg tgatgatcac cacctgattt cacaatgagc aggtctctaa aataggttag
    21481 cagatccgtt gcaaagcgac tcatgctctt gccactatca taaattgttt ctagattagc
    21541 taaggcctga cttgtttttt gcctgatgag atgctgaacg tagtcgtcta aggccgaaat
    21601 agaaatagag cctgtgattt cttctgcaat agcaagcgtc actcgattgt caaaggatag
    21661 gctcaaggcc tgatctaaaa tggatagggc atcacgcatg ccaccttctg ctcgtcttgc
    21721 aattaaatga agcgcctcta tttcataggc tatgccctcc ttgtccagta tcgccgccaa
    21781 atgctcacaa atagctggct gcttaatggc tttaaattca aatcgctgga ctctagacaa
    21841 aatagtagct ggaatcttgt gtagttctgt tgtggctagg ataaaaacca cattgtcact
    21901 cggctcttca agggtcttta ggagcgcatt gaaggcccct gttgatagca tatgcacctc
    21961 atcaataata taaaccttgt aggttgcccg gctaggagca taggttgact tatctcgaat
    22021 atcgcgaatt tcatcaacac cattattaga ggcagcatca atttcaatca cgtcctccag
    22081 gctgccagtt gtaatatctc ggcaaatatc acaatgattg cagggctctc ccttgacctg
    22141 attagggcag ttcattgcct tagcaaaaat tttggctgcg ctggttttac cagttcctct
    22201 tggacctgaa aagaggtaag catggcttat cttttctgac tcaacagcct gctttaaggt
    22261 ggtcgaaata actgactgcc caaccatttc agcaaaggtc tggctacgat acttccggta
    22321 aagggcttga tacattaatt ctcaactcca aacatgtcaa aacgaaaaga tgtattttct
    22381 agtaataagg ctacaaattg ctctaaatag tcttgatcta tctgatcata atcagcaaca
    22441 agactggaat ccaaatccag aacaccaaca agcctgccag ccttaagcat tggcacaaca
    22501 atctcgctca tggctgctga atcacaggaa atgtaattag catgcttttt gacatcatca
    22561 acgatgatgg tttgaccaga ttgagctgat tctccacata ctcccttgcc aagcttgata
    22621 tgcacacagg aaacctttcc ctgaaaggga ccaaggatca attcttgacc atcaaaaagg
    22681 taaaagcctg caaaaacaga atgaggcagg gtcattttta agagggcact agcattagag
    22741 agattggcca aggcattgct ttcattagaa aataaggctt tagcttgagc caataatagc
    22801 tgataatgtt caatttttgt cgtcttattc atggttctta ttataacata tctgctacta
    22861 atcgttaaac gatttccaca ggaaaagaat tttaatcagc ctctctagaa aagaaagaga
    22921 ttttatgata aaatagtgag taatattaaa aaaataggag agtcagatgc cgttgttgag
    22981 atataaaaag attatcgcta cgaccttatt tatgttatta gtgtttaatg gtattgagta
    23041 tgaatgtcta aaccttgtca gtcccaaaca aaccttttac caatccgctg ccttaatcct
    23101 ctcaaccagc ctactaggga tctatctgat tcccttttca ctggctattg cttatctcaa
    23161 gcgcatctac cagataagga tctcaaccct gctattagct gggctaggcg gtctttatat
    23221 tagtggcttt ttagcctcct ttggcaatca ggttttagag caattttgga ttagcctgat
    23281 aaagcccaat attgccttag aggagtggac gggagctttg acagggcctt ttgtggaaga
    23341 gcctattaag gcctttgcag ctatgcttgt catttatttg ctgccagcta ttaatcttaa
    23401 gcaaaaatta gtcatcagtc tcatttctgg catgggattc cagctgactg aggacattag
    23461 ctatattgca agtgcggctg atcggtccat aaatgacatt ttgcctacaa cgcttgccag
    23521 gattagcagc tcaccaaact ctcattgggt ctatactggt atttttacaa tgggagcata
    23581 ccttttaatt aaaaaatctc aattattccc aaggtctctg cagattttct gggtggtaag
    23641 tcctctagcc ctacatttta tatggaactc tcctatctca gatttagctg gtgtcgcagt
    23701 tattcatgga acaataacaa cccttatctt tatcagtcta ttcaaaaaaa tccatgccct
    23761 agacgacagc atcgcctact agcgtcatag gacacgagca accaagccca gccgcatttg
    23821 ggcatgtgat ggctcatatg catatatagc tactcacctc tcgcttaagc tataggcagc
    23881 taaataccta tcacaatagc agaaaaaatg actaccagtc ttaaaagggc tagtagtcat
    23941 tttaagctaa aaacaagcac ttcttacagg atataccact gatacagata atagcaaagc
    24001 acaagggtca tcagtatccc catataccat gaaaggacaa aataccattt cttcgtttta
    24061 tggttaaaat aatgcccagc tagataggct ccaatcccac cacataagag tgacaacgtt
    24121 aatagcattt tctcagaaag tcgccattga cctttttggg ctctgtgttt atcactgcca
    24181 taggccgcaa agaccacagc attccaacca aaaagcaaga ttaggcttgg tagcatttgt
    24241 ctgtctccaa tcacagcact acagctcacc taagatgctg gcaatctttg tgttgatgag
    24301 atcaatagca accacattgc taaccccttc tggaatgaca atatcagcat agcgcttact
    24361 tggctcaata aattgatgat acatcggctt gacaacgctt gtgtactgct caataatgct
    24421 ctcaaggctt ctgccacgct caaccatatc acgctgaata cgacggataa tccgaatgtc
    24481 atcatctgta tcaacaaaaa gcttgatatc catcagctca cgcaaacgct cgtcctctaa
    24541 taccagaatc ccctcaacaa taatgacgtc ctgaggctct tggcgaaaag ttctgttgct
    24601 gcgagtatgc tccttataat catagattgg aatatcaaca ggccggccag ccaagagttc
    24661 ctttagctgc tgaatcatga aatccgtatc aaaggctaac gggtgatcat aattagtctt
    24721 aaccctttcc tcaaagctga tatgtgattg atccttgtaa tacgaatcat gctgaatcat
    24781 cgcaattctc gcatttggaa agctatttaa aatggcacga gacacgctag tcttaccacc
    24841 accagaacca ccagtcacac caataataat gggtttttta agcattgtaa actccaaatc
    24901 taaaagtctt tcggtctatt ttaccaaatt tgccactata atgctataat gaagagaaaa
    24961 caaaataaaa ggatagatat atgataacca accttcccac tcaatggcag gaaaagctgg
    25021 caaagcttgg ctttactaat ctcaccccaa tccaagagca ggtctttcag cccattgttg
    25081 atggcaaaag cctattaggc attagcccca ccggaacagg caaaactctg gcctatttat
    25141 ggccaagcct tctcaggcta agccctaaaa aagcccagca gttgctgatt ttagcaccta
    25201 atactgagct agctggacag ctttttgagg ttaccaagga atgggcagag cccttaggat
    25261 taactgcgca gctctttatt tccggaagca gccaaaaacg ccagatcgaa cgcctcaaaa
    25321 aaggcccaga aatcattatc ggaacaccgg gacgcatttt tgaattagta aggcttaaaa
    25381 aaatcaaaat gatggccatc aataccatca ttttagatga atacgacgac ctactgagtg
    25441 actcccaata ccagtttgtc caaaaactct cccattacgc gcctcgtgac catcaaatga
    25501 tctacatgag tgctactaac aagatagagc aagccagtct agcggatcat accttggtca
    25561 ttgatctgtc taagcaagca ttgccttgca ttgagcactg ctacatgctg gttgacaaaa
    25621 ggcatcggac cgatatccta cgtaagctag caaatattcc tgactttcgt ggtctggtct
    25681 tttttaacag cctgtcagac ctaggtgcta ctgaagaacg cctgcaatat agtggagctt
    25741 ctgttgcttc tctagccagt gatgtgaatg tcaagcagcg aaaggccatt ttagaagcct
    25801 ttaaagagca gagcatttca ctgctgcttg cgacggacat agtcgctcgt gggattgata
    25861 ttgaccagct agaatacgtc attaacgctg aggttccccg taataaagag caatatactc
    25921 atagagctgg gcgaaccggt cgtatgggac gatcagggat tgtcataact cttgtcagtc
    25981 accctgaaga catcaagcgc cttaaaaaat ttaccaaggt cactgagatg tacttgaagc
    26041 atcagcaatt ataccaaaaa gaaataagag gctagctcaa aggatataaa cctaaaaagc
    26101 ttgcctccaa gtatgatgta aagcaactaa tcactatttc ttacccttgc tactaaaaaa
    26161 acgaacgtaa agtccttctg acatgaagtc aaaaccttac gttcgtttta tattatactg
    26221 acaccactgg ctttattagt atagtagata ctggccatgc ttagccagac tagatacttt
    26281 cttgaagtga gcccgccatt tagtcatgct ctagagcctt acttgctttt tctgactgac
    26341 tagcggctac catatagctc agataaggtc acacatttgt atccttccgc ttttaggtat
    26401 tccataatac ttggcaaggc atctacactg gtctggtgaa tatcgtgcat tagaacaacc
    26461 cctccaggct gcaattgctg cttgacattt gccatgatag cagcagtatt acgattttcc
    26521 caatctctgg tatcaactgt ccaaagcatt tccttaagac ccgatgccct tctaacaata
    26581 tcattagtag ctccataagg aggacgaaga tagactgggc gttttccaca ggccttttcg
    26641 atggcttgat tggtcgtatt gatctgtgtt tggatctgat caacggttag ggtcgtcaaa
    26701 tcagggtgat cccaagaatg attctcaaca tcatgaccag cagcactaac cttcttaacc
    26761 aaagcctcat ggccaacaac cttagacccc atcataaaaa aggtcccctt ggcctgatat
    26821 ttggccaaaa tatctaaaac ctgcggtgtg gtcacagggt ctggaccatc atcaaaggtc
    26881 agagcgacta gcttttgtcc ctctttttct gcctcttttg ccttcttttc ctccaaatac
    26941 tcttcataag cagtcttgtc tgaaccctct agaaaatctg gattaatcac atcaaacagg
    27001 cttgcaagag gtattgacat atgaccaaat aaaataagat tacccgaatc aatggcaaag
    27061 ccatcgctta atacctgatt tttttctatc atcgtatcag tgctcagctt gatctctttg
    27121 cctggataaa gcttgccaac ctcttcctcg atgcgatcta agcgaccagc aactagctcc
    27181 tctagcttaa aggggctata atcctctttc acatggtaac gactaacagc cttttctgta
    27241 gtctttttta gaccaaataa ctgaggcttg tagaccgtct tgtagataac caattgattg
    27301 acctgcttga tatgtgaagc ctcaagctta ggctttacca tgataacagc cttgtcagtc
    27361 tgcttgcctt gatacagaga cataggcaga tttgacacat aaaaatcgtc agccttctca
    27421 atcggagaca ggtaatacca atcctgcttt cctttcttga gatacttgac ctttttgatc
    27481 tttggactat ccttagaagc agtctgttcg agcttaatga ctctctgagt atcctgccct
    27541 attttccaag atctaatgaa ggtaaacgca acaccgacca acaataaact taataaaata
    27601 atgagaatat aatttagctt tttcaatctc gtcctccaat taccctacaa ttttaacaca
    27661 agatagttgg aaaataaata aaaaaagtta ggtttcctta acttttttca gtccaaaata
    27721 agggcaaaaa agtgttttat ggtgcaggat ttgcctgagt tattttccct ttatcacagc
    27781 catttgtcac tggataaggg gctagatatt atacctaaag cttctcttta ttgctatcat
    27841 tattctgaca ttcttaggca tgctatttcc cttgatagga cttgattgct gtttctttag
    27901 cttgtaagga tctcctaaaa atgagagtat ttttaagcct ataatttata tattcgaaaa
    27961 attttgacaa aaatgaggaa aaatattgat ttatttagct ttagtgataa aatgagggtg
    28021 aaaaattaaa taaaggagga cattgatatg tctcagaagt tgggaaaaca acttattcgc
    28081 tctgttgtta ctgccttagc cgccatagca tttggaatat ttcctgcaag cgagacgact
    28141 aatcatatca cctatgcaga ggttaactcc ttaacccctt cggtagaatg gcctttagag
    28201 cagtatccta attactatag catagaagga aagtctaata tcaacaccaa ggattttcct
    28261 aagctataca ccactaccga aaaggtttac aaaaaaagtg gtcgaagcac taagcgcgtt
    28321 actgtttctg atctgcaata cgctgcactt gatggctatg gccgttcagg agctgcctat
    28381 ggtattatca caaaggatat gatcgcgatg tcagccggat accgcgaaaa atgggaaagc
    28441 aatcctgagc caagcggctg gtatacatat catttcaaag aaactggcaa gctagctact
    28501 gaggccgact accttcacag caaaagcaag atcaaacgaa cctcaaacaa tagctatgaa
    28561 agcatcgtcc ttagcaacgg taagattcgc aacggctatc tttttgatcg tagtcattta
    28621 attgctgaca gcttaggtgg tcgtcctttt agaaataatc tcatcacagg tacacgtact
    28681 caaaacgttg gcaacaacga ccgcaagggg ggtatgcagt acattgaaaa caaagtccta
    28741 aactatatta accacaaccc tcaggttcac gtttattaca aagccgtacc aatctactca
    28801 ggctctgaat tactccctag ggccgttgtg gtttcagcgc tctcctctga tggtaaaatt
    28861 gatgaaaccg taagagtctt taacactgtc aatggcttta ccatcaatta ccaatatagc
    28921 ggcatcagcc atgataaggg catggaggct tctagtgagt cagaagctga ggatattaca
    28981 gacgaaagca ctccagtagc tgaaccagct gatgaggagg ctatggagac agaggctgct
    29041 gctaacgaca caatagtcta tgttacaagt aatggccaat caaaggtata ctggtataat
    29101 aaggaccatc tgccagagaa ggtcaatctc aataaggttg tagaaatgac cgagcaggaa
    29161 gccctaaatc gaggaaagca ccattcctcc ttagaaaaaa taaatcaata gtctcataac
    29221 gactaacaca agagctggtt gaagcaacca gctttttttg tgtgatgaag gattagacag
    29281 ctccttagct aaaagataaa gaggctgata aagcactcaa cctcttatcg cttttataaa
    29341 tgctctggta ctgcggctaa tagctctgat agcttgcttg catcactacc acctgccatc
    29401 gccatatctg gcttaccgcc accacgaccc gacacgattg gcgctaaggc cttaatcaga
    29461 ttgccagcgt gagctctttt atccttactt gcaacaagaa cattgacctt ctcaccaatg
    29521 cttgcagcca gcacaaggac atctgaataa tctctttgct tccaattatc agcaaaggta
    29581 cgcaagactc ctgcatctga tacggatacc tcactagcaa tgtaacgtag accgtttgct
    29641 tcctggacct ttttaaagac atcaccagcc tgagctgctg ctgctttttc ttttagctct
    29701 gccatttctt tttgcaaatc gcggagctgc tcgctgaggc tcacaacctt acttggaagc
    29761 tgttctattt gcggcacctt aagcgtatgt gcaatttctt ttaggatgtc ttcttgcttg
    29821 cggaagcttt caaaggcctg ctgacctgtc actgctatga tacgacgtgt tcctgagccg
    29881 atcccctctt ccttgataat cttgaaaaga ccaatttctg atgagttgga caagtgagtc
    29941 cctccacaaa gctcaacaga ataatcgcca atctgaacaa cacgaacagt tttgccatat
    30001 ttttcaccaa agagggccat agctcccata gcctttgctg tttcaatatc agtttctgtg
    30061 gttgtaatag ctaatgcctt ccagatttgc tcattgacct cttcttcaat acgacgcagc
    30121 tcctgggctg taacggcttc aaagtgtgta aagtcaaagc gtaaaaaggc ttcttcattt
    30181 aaggaacctg cctgagtggc atgttctcca ataaccttgt gaagggcagc atgaagcaga
    30241 tgagtagcgg tatggttttt ctcaacagca tagcggcgct tgtgatcaat agcaagagta
    30301 taaacagtgt ctaatgcaag gcttgcaaga acctcaacag tgtgaagagg ctgaccattc
    30361 ggtgcttttt gcacatctat cacacgagca acaaggtcac ccttatcatt tttgataacc
    30421 ccatgatcgg caacctgacc acccatttca gcataaaacg gtgtctgatc aaacacaagc
    30481 aaggcctgtc cttctgaaac catctcacta cgctcattat caacgatgat aactgataag
    30541 cgagaggcaa cagtctctgt ttcgtacaaa aattctgatg gctctgtgat gcctgccagt
    30601 gtctcatttt gcatgcccat tgagccaccc ttaacagctg ctgcacgggc acgatcctgc
    30661 tgctccttca tagctgcctt gaagccttca tgatcaatct tatagccagc atcttctgct
    30721 aattcttcgg tcaattcaac tggaaagcca taggtatcat acagcttaaa gatatccttg
    30781 ccatcaagcc tgtcttgccc cttttccttt agctgcgcca gcaattgatc caaatgccct
    30841 gatcctgcat caatggtacg tgcaaaggtt tcctcctcac gcttgataat tttttcaata
    30901 aagtcacgct tctcaagaat ctctggataa taggactcca tgatatgacc tacagtagct
    30961 actagcttat aaaggaaggt ctcatgaata ccgagcctac gaccatgcat aacagcacga
    31021 cgaagcaagc gacgaagcac atagccacga ccttcattac caggtagggc accatctcca
    31081 atcgcaaatg acaaggcacg aatgtggtct gcaatgacct taaagctcat gttgtcacca
    31141 tcttggtcgt aagtatggcc agatagcttt tccacttcct tgatgatcgg cataaatagg
    31201 tcggtttcaa agtttgtttt tgcgccctgc ataacagcca caagacgctc taagccagca
    31261 cccgtatcaa tgtttttgtt tggaagctcc ttgtactctg agcgaggaat tgtagggtct
    31321 gcgttaaatt gagacaaaac aatattccaa atttcaatat aacggtcgtt ttcaatgtcc
    31381 tcttccagca atctaatccc aatatgatca ggatcataag cctcaccacg atcaaagaaa
    31441 atctctgtat caggtcctga cgggcctgca ccaatctccc aaaaattttc ctctaatgga
    31501 atcaaatggc ttggctcaac gcccagagca atccaacgat tgtaagagtc cttgtcatct
    31561 gggtagtagg tcatgtataa tttttccttt ggaaaatcga accattccgg acttgttaac
    31621 aattcaaagc cccactcaat cgcttcgtcg cgaaaataat ctccgataga aaaattacca
    31681 agcatttcaa acatagtatg gtgacgagct gtcttaccaa cattttcaat atcgttagtg
    31741 cggattgact tttgagcgtt ggtaatacga ggattttcag gaatgactga cccatcaaaa
    31801 tattttttga gggtggccac accagagtta atccaaagca gggttgggtc attgactggc
    31861 acaagattgg ccgaaggctc aatagagtga ccttttgatt tccaaaaatc aagccacatt
    31921 tggcggattt gggctgatgt taactgtttc atgattaaga taccaagagc gattagagag
    31981 actgggtatg attgtcctta gcataagtag cctggggaga cgatctctac tcgcattcag
    32041 ttcctttcgt tgatttttta tgggattagg ctaaaagcca tcaaaacaaa acaagcccat
    32101 atcacagagg gcgaaaaccg cggtaccacc tctattcaat gagcttgtca ttcttaatta
    32161 cttatatcag ataaaatcac attaagcagc atgcctatca gattatccgt aactcacagc
    32221 aaccgtcact tctctgggtc aaatccttga taaacaattc ttaactaaac cagtataaag
    32281 cttttttgag cattcgtcaa tgaaaatcta tttttctgac ttagatttag aagattgact
    32341 atccttgctt gagtctgaag atgatttctg atctgacttg cttgtgttcg ccttgcttgc
    32401 ttttttatca gtattggcat actgtgccaa gatattagca aatgcttggt ctttgatctt
    32461 aacatttgcc ttgtctaagg cctttgcaat gaccttattt tggaaatcaa tgttttgtgt
    32521 cttttcagcc aagacaattt cttttagacg tttcttatat ttcttccaat cagaagcctt
    32581 ttcggctttt ttggttacct taacaatata gaacttgttt tgataagtag ccggatctaa
    32641 gacagaaacc acctctgaaa tatcaccctc ttttaatcct gaggcggcct tgatcacatc
    32701 tgctggtaac ttagtgtctc ctgagtcaaa cttatagtct accttcttgt ctgctgctgt
    32761 tgtcttttcc ttagcaatag cagcaaagtc agcaccctca gccttaacct cacctaaaac
    32821 agcctttgct gtttcttcat tgtctagagt agtgacctga gtagtcattt ctggtgtgta
    32881 tgactcatag gcttttttgt aatcagcatc tgtcagctct tttttagctg cttctttaac
    32941 agcatattca accagcatgg ctgagcgaat ttgacgcttg taggtatctg ttgtcaagcc
    33001 agactgcgca agggctgcag agaatgacgc accgtattgc tcagctgatt tattgtaagc
    33061 ttcttccgtt cttttcttag aaaccttttt accgtattgg tcctcaaaaa cacgactaac
    33121 cacaaggttt agcattgctc tttgagaaat ctctgtattt tttgtttcat tgtaaaaatc
    33181 actaacactg atagtgtcgc ccttcatcgt aatgacactt gtattgtcat ttgtagactg
    33241 acaggctgct agggtcattg ctgatgctag ggttacgata ccagcaagta atttagttga
    33301 ttttttcatg tgattttgtg ctcctttttg tcattaacca gtatattata tcacaatttc
    33361 ttaaacgtaa cttaatctaa caaacgaata tctgcttgat ttttacgaat catcagcaag
    33421 ccatcactaa gcggcagcag gctggctgtc aatccaggat tatcaagagt tgctgcaaat
    33481 aagtcctgaa ggccacgata aatcgtgcgc tgtcctctcc gaacctcctt gatcggctta
    33541 gcaatgtcac ccccctgaaa cacatcatct aaaacaacca ttccacctat ttttaagtgc
    33601 tttaacacct ctggaagaaa ctgaatgtat tttgattttg cagagtccat aaaaacaaag
    33661 tcaaactcgc cagtaagtcc tgctaaaaga tcagccgcat ctccttcaag aagggtaatt
    33721 tgcttgcggc tatcgtattt tgcaaaattt tccttggcaa agccaatcat ctcagcattg
    33781 cgatcaatcg ttataatctc tgcctcagga gcattttctg ccattagcaa ggcagaaaag
    33841 ccaatagctg tgccaatttc taaaatcctt ttgggctgca agctttgcaa taaaagcctg
    33901 aaataagcaa caacctcatg ctggataatg ggaatatttt cttgtctggc aaaggcctca
    33961 agctctgcta aaaagccttc gttttgcttt agctgcgttc gcatgtagtg aacaatgtct
    34021 tctttgacaa tagagcggcg catattatga tttgcatttt tactatatga tttaaccatg
    34081 ctatccatta tataaaaaaa ctctaggtaa tgctagggct ttcactagcc tattcacctt
    34141 tgacgatctg agtagtatct atcaaaggag ctcacagaca gccttaagct gcttgacaat
    34201 gctatcacaa gcagacaagt cctgtaaggg ataatcagga ttggcaaagc cgatacaggt
    34261 catctgagca gccttagcag cctgactacc atgcttacta tcctcaatga caaggcaggt
    34321 cttgggatca acgcttaacc attcagcagc cttaagaaaa atatctggcg ctggctttga
    34381 gcgagcaacc tcttcaccac taactaacac ctcaaagcag tccaaaagac ctagtgcagt
    34441 gagatttcta ataatatctg ccttaggcga tgaggaagct actgccaagc gatagccctt
    34501 cgcatgcagg tgcttgatta attgagcagc acctgctatg gccttgacac cgtcacgctc
    34561 aagcattgct tgacgacgat gattcatctc agcgatgagg gcttcaacag aatcctctag
    34621 ctgacactcc tttttcatag ttgtccacat atcgtcaaag gtggttccca taaactggta
    34681 ctgatacgct tcattggtat ctatgcctcg gtccaatagc atttgtgtct tggttgacaa
    34741 aaagatatat tctgagtcaa caatcacacc gtccatatca aaaataaggc ttgttttcat
    34801 catctacctc ctcttatgct atatctcagt caggtcaaga gcaagactat taattactag
    34861 agctattttt accagaaaaa agctcaacaa tatctgacag ctgactaata tgatgattat
    34921 catcactatc tggcagcaat aggttgatag agctaatccc agctgccctt gctgcagcaa
    34981 ggtctaaggg cctatcacca atatagtagg tctgcgactt atccatctga taatgatgaa
    35041 tgagaaaaag aagcgcttca gggtccggct tacgcttaaa gccacaatct gctgtaatca
    35101 cctctgtaaa gtaatcagca atccccagac gctgcaaaac agcctgagtg gttcgtcctt
    35161 tatgagtcac aataaaaggc ttaaccccct gctgagaggt taaggctaat gtttccttgg
    35221 ctgtaggcat tagtgctatt aggtgatcac gcgcttcctg ctctcgggta aagaaggcca
    35281 gcaattctga aaaatccagc tgatgtgcct ctgctaacct cttcaaaagc tgtccgatgg
    35341 attcttgaat aatcgtatcc ataacccaag cctcatcaaa gggcagctga taggtctgat
    35401 acaataaacc tagcgcctga cgaatagcct cagaggattg gactagagtt ccatcaaagt
    35461 cccaaatgag attaactgtc acaatcctta cctcttaaat caatccaata acgagcaata
    35521 gcctgccctg ctaagcttgt agtagggtaa tcatctgcca cctgaacaat atcctctaaa
    35581 ataccaccag ccttttcaat ggtttttcga ctggctatat tatctttatt agctgttatt
    35641 aagacacgct tgatcccacg ctcttgatat tgctgtaatg caaaggccag caagtctgtc
    35701 ataattccac gcccgcgata atctgtcctt gtcacatagc caatatgtcc gccaattgtt
    35761 gctaagtctc ctttttccaa ctgccagcga cagcctattc tagccactag ctgaccatct
    35821 aaaaaatagt aataattagt gctagtggac cagtcaggat gatcagtttg gacctcaaac
    35881 cgtctagatt gctcaacaaa ggctgcaaag tcctctactt ttttggtctc aacaaaggta
    35941 ttacctgaag ctttttcagc taacagtata tcctgaaagc gcttaaaggc tgcttgatca
    36001 gctaaagcaa ttgttctaat ctctttcatg cctggctcct ttttattatg ctaaaaatca
    36061 actgggcatt tctcaagcat tcatcatgcc aacgaaaaag agctgcccct agaactgttg
    36121 atgtaatact acgtctagag gctgcccaca ggcctttaag ctaggctgat agacactgac
    36181 tgctgctatt taccaatagc tcaaaaccta agaggagatg gcaactatta gagatgtgcc
    36241 cctcttgcca ctaagtcctc tagctctgtc aaacgctctt caaagaccct aaaggctgct
    36301 tctaggtaat cacccttagc catatcaaca ccagccttgg caatcacctc aagcggataa
    36361 tctgaatttc cagacttcag ataggtcaag tagtgatcaa tatcctcttg agtaccatgc
    36421 acgatcttat cagccaagta gctggctgca gcaaagcctg ttgcatattg atagacatag
    36481 tagttgtaat agaaatgcgg aatgcgagcc cactcatact ggataaaatg gttgtcctct
    36541 ttttttaagc cataatattt ttcgtttaaa tcagcataga gattattgag gtattcactt
    36601 gttaacacct cgccattttg atccgcctga tgaatagcgt gctcaaactc agcaaactgt
    36661 gtttgacgaa aaaccgttcc acgaaaacca tctaggtaat gattcaaaat agcaaagcgc
    36721 tccttatcat cctgcacctc atgtaacaag gcctcagtca tgatattttc attagtggtt
    36781 gaagcaatct cagctaagaa aatgctgtaa tctccataca cgtaaggctg tgtttcacgc
    36841 gtaaaggttg agtgcaggct atggcctgtc tcatgcacta gcgtatagag gttatcaagc
    36901 gtgtcctgcc aatttaagag cataaaggca ttggtatcat aggaaccacc agagtaagct
    36961 cctgagcgtt tgcccttatt gacatgcaca tcaatccaac gctctgtaaa ggcacgatgc
    37021 acacgctctg aataatcctg gccaaaaaca gccaaaacct tctctgcttt ttccaaggcc
    37081 tcatcatagc cgatagcaag atctgtctca gataaaggag tataaacatc atacatcttt
    37141 agatcatcta aaccaagcac ctcttgacgt agcttcaaat aacgatgaag cagcggcaaa
    37201 tgcttattaa cgttttctag tagggtatcg taaacagcct ctgggataaa gttggctgac
    37261 atcgctgcct gacgggctga agcatatttg tgaacacgtg ccttataatt ttgcaccttt
    37321 acattggttt gcagggtttt agcataggtg tgctggaatt gctcataagt actatacatg
    37381 gcttcatagg cagccctacg caccttgcgg tctttcgatt ccatcaagct aatgaaatta
    37441 ccatgtgtta gctcaacctc ttctccctta tcatttgtca caataggaaa agcaatgtcg
    37501 gcattatcta ggatactaaa ggtctcctca gcaccattaa agatttcttg tgcccctgct
    37561 aatagctcct cctcagcctg actaaggaca tgctcacgcg tcttgaacaa tttatcaaag
    37621 aaatggtcat agactgttag ctccggtgtc tcagctaaga aggcttggta ggcttcctga
    37681 cttaaggcca taaattctgg ctcatagaat gaaaaggctt cactaaattt agcataaata
    37741 ccagaggcct tagcttgata ttcttgatac ttggcaactg tcgtatcctg atcatttttc
    37801 atgctagcat aaacataaac cttttcaaca cgacgagcca gctccaaatg cagctctgtg
    37861 atatctaaga gactgctgct tgaatccaac aaatgcccag cctgctgcct tgcagcctca
    37921 attgctgcca gcagactatc tgcctctgtc tcccaagctg cgtctgttgc aaaaatagtg
    37981 cttaaatccc aagtgtactt ttcctctaga tgactacgat tatctgtcat acggacctcc
    38041 taagtttcta ttactaatca ttttaacata atatgctggt gaaaaaagct tttgcacctc
    38101 tttatttgct gcttttgcgt aatatttttc aaagcaatcg taatagtggc tcaaatcctc
    38161 atgaatctgg caaaagccag ctgagcaagc aatcggctta acctgtggat aataagcctc
    38221 taggggccta tcaagcaggt tatccccagc tagataagcc tcttcttgct ttttcaacca
    38281 tttgctatct tttgctagta aggctttttg aatccttctc agcaagtgct tatccatctg
    38341 gagctgatag gctgacaggc cttttctttg gtaaggcagc cgcaaaaagg ccaacaaatc
    38401 atcatctaag gaacaggtct ttactagata gctgacctta ccaaataaat cctcatgaat
    38461 c
//
LOCUS       DARYXZ010000019        38009 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYXZ010000019 DARYXZ010000000
VERSION     DARYXZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38009
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(80..1285)
                     /locus_tag="TV186_000840"
     CDS             complement(80..1285)
                     /locus_tag="TV186_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL1532253.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TV186_000841"
     CDS             complement(1538..2791)
                     /locus_tag="TV186_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1532254.1"
                     /translation="MRTLKNFITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TV186_000842"
     CDS             complement(3188..3808)
                     /locus_tag="TV186_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532255.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TV186_000843"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TV186_000843"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TV186_000844"
     CDS             4121..5347
                     /locus_tag="TV186_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1532256.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TV186_000845"
     CDS             complement(5457..5951)
                     /locus_tag="TV186_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL1532257.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TV186_000846"
     CDS             complement(5948..6730)
                     /locus_tag="TV186_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1532258.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TV186_000847"
     CDS             complement(6829..7368)
                     /locus_tag="TV186_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL1532259.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TV186_000848"
     CDS             complement(7372..7683)
                     /locus_tag="TV186_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532260.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(8070..8207)
                     /locus_tag="TV186_000849"
     CDS             complement(8070..8207)
                     /locus_tag="TV186_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1532261.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(8591..9835)
                     /locus_tag="TV186_000850"
     CDS             complement(8591..9835)
                     /locus_tag="TV186_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1532262.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TV186_000851"
     CDS             complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TV186_000851"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL1532263.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            11812..12657
                     /locus_tag="TV186_000852"
     CDS             11812..12657
                     /locus_tag="TV186_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL1532264.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(12853..16815)
                     /locus_tag="TV186_000853"
     CDS             complement(12853..16815)
                     /locus_tag="TV186_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL1532265.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(16950..18767)
                     /locus_tag="TV186_000854"
     CDS             complement(16950..18767)
                     /locus_tag="TV186_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL1532266.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKAADK
                     QQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(19127..19600)
                     /gene="perR"
                     /locus_tag="TV186_000855"
     CDS             complement(19127..19600)
                     /gene="perR"
                     /locus_tag="TV186_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL1532267.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(19637..20089)
                     /locus_tag="TV186_000856"
     CDS             complement(19637..20089)
                     /locus_tag="TV186_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL1532268.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(20329..22971)
                     /gene="polA"
                     /locus_tag="TV186_000857"
     CDS             complement(20329..22971)
                     /gene="polA"
                     /locus_tag="TV186_000857"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL1532269.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(23395..25125)
                     /locus_tag="TV186_000858"
     CDS             complement(23395..25125)
                     /locus_tag="TV186_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL1532270.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(25143..26339)
                     /locus_tag="TV186_000859"
     CDS             complement(25143..26339)
                     /locus_tag="TV186_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL1532271.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(26538..26780)
                     /locus_tag="TV186_000860"
     CDS             complement(26538..26780)
                     /locus_tag="TV186_000860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532272.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(26845..27936)
                     /gene="ulaG"
                     /locus_tag="TV186_000861"
     CDS             complement(26845..27936)
                     /gene="ulaG"
                     /locus_tag="TV186_000861"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL1532273.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(28131..29777)
                     /locus_tag="TV186_000862"
     CDS             complement(28131..29777)
                     /locus_tag="TV186_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL1532274.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(30081..30797)
                     /locus_tag="TV186_000863"
     CDS             complement(30081..30797)
                     /locus_tag="TV186_000863"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL1532275.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(30797..31660)
                     /locus_tag="TV186_000864"
     CDS             complement(30797..31660)
                     /locus_tag="TV186_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL1532276.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(31665..32330)
                     /locus_tag="TV186_000865"
     CDS             complement(31665..32330)
                     /locus_tag="TV186_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL1532277.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(32425..32910)
                     /locus_tag="TV186_000866"
     CDS             complement(32425..32910)
                     /locus_tag="TV186_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1532278.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(33126..33404)
                     /locus_tag="TV186_000867"
     CDS             complement(33126..33404)
                     /locus_tag="TV186_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1532279.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(33519..34952)
                     /locus_tag="TV186_000868"
     CDS             complement(33519..34952)
                     /locus_tag="TV186_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1532280.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(35435..36055)
                     /locus_tag="TV186_000869"
                     /pseudo
     CDS             complement(35435..36055)
                     /locus_tag="TV186_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(36057..36674)
                     /locus_tag="TV186_000870"
     CDS             complement(36057..36674)
                     /locus_tag="TV186_000870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532281.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(36661..37449)
                     /locus_tag="TV186_000871"
     CDS             complement(36661..37449)
                     /locus_tag="TV186_000871"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532282.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
     gene            complement(37520..37921)
                     /locus_tag="TV186_000872"
     CDS             complement(37520..37921)
                     /locus_tag="TV186_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532283.1"
                     /translation="MKLGKIKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGR
                     TKDYLVKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDT
                     KSGYLYALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT        10968 a         8903 c         7417 g        10721 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaagtttttt aatgttctca ttgtgattgg tttgatcctc tcttgcgctt
     2821 tgtattttgc ctttaaacgc taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaaa caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc caaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatcg cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 taatcgtcga cctaccaaag ttcagacggt tattttttat tgtttaatat gacgattgca
     8101 acgactaagc tgattaaggt aagtaagaaa ctaccaaaag ccagcatgag ttgaagggcc
     8161 tcgtaagtag acaataaaac gctcctttct gttggatttt gatgcattgc ccataggtat
     8221 caccaccttt cagaaatcag agccaccgcc ttagcttttc tgtaaagaac attattatat
     8281 cataatcaca caagaatccg tcaaatctta aactaatcag gcggcttttt tatgctctga
     8341 ctataggtct gaagagaaga tgctagatgt cttaggtggc tttccattta aactacgagg
     8401 tcttctttct cacagagtat agccccctct tttttcagct actgtttcgg aggcaagctg
     8461 gcatttcgtc taaattgctt ttgtttttcc ctgagcattc gaaaaaatcc tttatttcta
     8521 cctgacatat cactaaaaga gggtcctgtg accctctttt atagctatct gttagagaga
     8581 tatgcaattg ttagtcttgt tttttcttca agcctaggac acctgcgcta gcaatgacgc
     8641 tgagagctgc aagggtgaaa aatgggtgat ttgcctcccc cgtagctggt agcgtgccct
     8701 tttgagctgc tggagccgct gatttgtttg gtgctgactg aggagctggt gcctttggac
     8761 tagctggctg ctctgaagat tttggtgcct gtggagcagg ggattgctcc ggtgcctttg
     8821 gagtctctgg ttcttttggt gcttgtggtt gctctttttt ctccggtgtt tctggagcct
     8881 ttggcacttc tggcaccttt tgtgattccc cttgttgacc tggcactcct tgtggcccag
     8941 tatcaccttt tggaccttgt tgacctggtg cgccttgtgg gccggtgtcg ccttttggtc
     9001 cttgttgacc tggtgcgcct tgtgggccgg tatcaccctt tggtccttga agtccctgtt
     9061 cgccttgtgg cccagtgtcg ccttttggtc ctggttgacc tggctctcct tgcgggccag
     9121 tatcaccttt tggcccttgt tgacctggtg caccttgtgg gccggtatca ccctttggtc
     9181 cttgaagtcc ctgttcgcct tgtggcccag tatcaccttt tggcccttgt tggcctggcg
     9241 ctccttgagg accggtgtcg ccttttggtc ctgggagacc tggttcacct tgtgggccga
     9301 tgtcaccctt tggaccttgt tgacctggct ctccttgtgg cccagtatca ccttttggcc
     9361 cttgttggcc tggttttcct tctggtccct gtgggcctat tggtccacgc tcaccaactg
     9421 gtccgcgttc ccctcgaagg ccttgaggtc ctgcgggacc cattggacct tgaggtcctg
     9481 gtatccctaa tgaatctttc tcatacaatt tgtataattg ctctgattgg cctgtcgatt
     9541 tttttaaaaa ttgctccact cgccatagat atcttaaaac attttctagc attcgaccat
     9601 tgttataatg tgtcgaagtt tcccagtcac ttgagctacc agaaccagga ttaagtattt
     9661 ctttttttat gaactgttga aagaaatatc cttgattata catagaagga tatgtaaagt
     9721 cttctgccct tacatcattt ccaatcccta agctagctat ggttgctagg gcgacaactg
     9781 ctgagcagat accgtacttc tgaacaagcc tgatacttgt tttcttgttt ctcatgttta
     9841 tctcctttta gtttagaaat gttaacgatt tctaatcttt tttcttccaa agaaaatctt
     9901 aacatgacgc ttgcgggctg tgaatatgtt ttggggaatt cgcttccgta gtttcgtttt
     9961 tttctaatca aagggtcaat tgtctgacgc tagtgtcttt tggcattggc ctttagctta
    10021 ggaagactgc ctatgttagc aagcttttca ttagcttatc cgttttgata aagggtaagc
    10081 gacgaggata atctgacttt gtcttttgct tttgttagat tttttaatgt ttttttgatg
    10141 tctgatgact tttaaaaaaa gccttctttt gataggcaag cttaaaaggc ctaggcaaaa
    10201 gcccagaccc ttgctgctat tatctgttat tgtggaaagc taccgctctt tggcactgtc
    10261 atgcttaaaa attgcgactt gagctattgt aaccatagcg ctcaaggaaa tcctgacgaa
    10321 actctaaaag gttatcgtcc aagatagctt gacgcacctg cttcatgagg tttactaaga
    10381 agtataggtt atggtaactg gtcaagcgca tgccaaaggt ctcatcagcc tttaagagat
    10441 gacgcaggta agcacgtgtg taatgctgac aggtgtagca gtcacaatga tggtcaagtg
    10501 gggtaaagtc ctctgcaaac ttagcatttt tcacaacgag acggccctcg ctggtcatgc
    10561 aggtgccatt gcgagcgata cgggttggca ggacgcagtc aaacatgtca accccacgaa
    10621 tcaccccatc aatcaggcta tcaggtgcac ctacccccat caggtagcgt ggcttatttt
    10681 caggtaaaag tggcgttgta aaatcaagga cagcattcat ctcagcatgg ctctcaccaa
    10741 ctgccaagcc accgatagaa tagcccggaa aatccatgct cacaaggtcc gcagcagatt
    10801 gacgacgcag gtcctcaaag ccagctccct gcacgatacc aaagaggcct tgatcatgag
    10861 gacggcggtg agccttcaag ccacgctctg cccaacgact ggtgcgctca atggattttt
    10921 tcacataatc atagggctgg taaaattgcg ggcactcatc aaagctcatc ataatgtcag
    10981 accctaggtt attttgaatg gagatcgctt tctctggtga taaaaacatc tttgagccat
    11041 tcaggtgatt tttaaaggtc accccctcct cagtgatgtt tctggagtct gccaaggaat
    11101 aaacctgaaa gccgcctgag tctgtcagaa ttgcctgatc ccagttcata aatttgtgaa
    11161 ggccgcctgc acgcgcaatc agctcatctc ctggtcgtag ccataggtga taggtatttg
    11221 acaaaataat gcctgaccca atctccttga gctcctcagg agactgtgtc ttaaccgtcg
    11281 cctgtgtccc taccggcata aacatgggcg tcggaaaggt cccatgcggg gtaataatct
    11341 caccgagacg agcacctgta tgcttttcct ttttgatcaa acgataagta atagggtaat
    11401 tagtcattgt ttcttttttc cttgctatca agataaacag tcttgagcgt tttgcatacc
    11461 acttacaaag cacttagtca agcggtatgg gcttgtttag agccctatca ttttatcaaa
    11521 aaatctctga cttgtcatgc cttcaaagag acaagatccc gaagcaatgg cacgacagac
    11581 gcatgaagga gttttagcaa gaaaagaaag ctttctgtcg ttcaatgttc agctatttca
    11641 agtatatgtc ttatctttta taaactttac tacagaaaaa tcgttgaaaa tgtttgcttt
    11701 actctatact atcattcaga aatagctgtt tcgcgcgttt gtcgtgagca aggacggtat
    11761 gggtatcact ggctcctaga atatggtata atgtaccaaa ggagttgtac gatgtcaatt
    11821 agagaaataa aacgtgaagc tagacagact ttaaagggac taaaggggaa atacctctta
    11881 tttttagtac cgataatctt atctattttt tactcaggaa ttgaggttca tcagacctat
    11941 gtgaccactc aggggattga ggtatcagtc ggggcaagct actttccttt gattgttctg
    12001 ataatgctga cggtctttac cttatcagca gcctatacca tgctagatgt tatccgctac
    12061 tatcgtcgtg aggtctcttt ttcagaggca acgatagctt tttctggaaa cttgtttggc
    12121 aaggtccttg ttttgttgat catcaaaggg ctcctattta tcctatggtc tttgatttgg
    12181 attgttggct tggttattct aacgattagc tctgcggcat tactgacaag ctacaatact
    12241 ggtgctgctg tgatgactcc aatcatcttt atggttattg gttttgtgat ttttattatc
    12301 gggcttattg tttatatgaa tcgttattgt gcttacagca tggctgagta cattctctat
    12361 gacaaggtca aggaaggcac ctatatgggt gctattacgg caatcgaaga gagcaaggac
    12421 atgatctcag gctataaagg aaagtatttt ttactacacc ttagctttat tggctggttt
    12481 atcctagtaa tcttgtcttt tggcttgatc tatatctacg tactgcctta ttacaccact
    12541 gctgatgtga ccttttacca ccatttaaag cacattcacg atgaaacaga gctgccgata
    12601 gatgctgaaa ggcttactat cacaggttca aaagaagccc catctgctat tagctagcct
    12661 taacgatatg cctctatgtc tctcatgacc ttgttcagag tagacataga ggttttttgc
    12721 atgacctttg ataacttttt tatagtaaaa aagaggagcc catcagttgc ctatccaaag
    12781 ctagatgaca catctaacgg ttggaaggct tgcttacagg ccctctttta gcaatgttag
    12841 cccaagacta tcctaaagct gctgaaaagc tcctcggtct aaggcatagg cagtcgtcca
    12901 atggctctca cgatagtaaa taaagagctg gctatctaat agctcatcaa ttgaggctgc
    12961 tgttggcaga cctgctaggt caatgaaata atcccctgga agaagctgtt gtagcttttc
    13021 cattaaggcg gtattaacag cggtctttgc tgctggtaat tgactagaga ttgataagcc
    13081 ttcaaaggtc tttaaatcta tgttttctga ctctaaagct gattttaagg ctgatttgat
    13141 caagtctagg ctgtattcag catctaaggc ttcatcgcct gatgagaggc tattcatcgc
    13201 caatacatac aaagggcctg ctgccttatc ctgataggta atgacaagtt gatggttcag
    13261 caaatcagct aagtcatcat aagtaccagt gttctcaaga gtaatgtaat aagtccctgt
    13321 gagccctaag tccttgattg tctctaaaat cttgccttgg attgcttgat ttttttcagt
    13381 tgttgccgct gttagaccac tatttgtaat agcaaagctc tcaatctctt tggtagctgt
    13441 attggtctct tttagaatgg ttagaatact atctttaagc gctagaatat catttctaac
    13501 cggtgcttca atagggctag agatgtcttc aaagaaacga taagcagaac cgctgacaaa
    13561 tttattggcc tgtccgctgc tttttccata ggtgtctaag gcagttattc taacaaatcg
    13621 acctgttgtt ggtgtaaagc tgactgtttt tagctcagta ttttgcttcc aatcagtgct
    13681 atcgacaacc gttgtccaga ccttaccgtc tgagctgatg tcgacctttg cagaatggat
    13741 cataccatta acacctcctg ggagataggc aatagcagag aagtttttat cgtccttaaa
    13801 ctcaacagta tatgacttgt cctcagtaac ctgattaaat aaggtatgcc attgggtggc
    13861 catatctcta ccatctacca tatgcttgcc agacctgcct gattgctcat tagcataggt
    13921 caccgcctga atatcatcaa ttgagatgta gtgcattgta ggatcagtgc tgtctgcggt
    13981 aaaggtatag gtaacgctgt cacttgctag actggtgcca tgagcccgat agcgagcaag
    14041 aactgtgaca gtgtcattga agcgctctgt gccatcataa gcctgccaag actggccatt
    14101 atccagactg acctccaaat gttcaatagc accaatcaag cgattttcca agtcattgcc
    14161 ataaaggctg ctgttggtcg gtgctgctgc ctttgtcagg ttaatcctgt aggtagcaga
    14221 taccgcgtca aagccaacta aaataccgtc ctctatatta agcttggcca aaaggtcatc
    14281 actaaaaacg ataaccttgt ccttggtttc aagccatgtt ttcccattat caatagaata
    14341 gcggactgtc aaatctgtat cctgataatt ctcatgcaaa cgaagggtct tgtcatcaaa
    14401 gctaaagctt gctgtttcga ttggattgcc cgttaggata tagttggcga taattctaac
    14461 ctcattagat tggagcactt ccttatcagt tgctgttttg gctgcgatta gagcgttata
    14521 gctcagtaaa tctagctcag ccttagctgc ttgatcgctg atattaggcg tgatacgctt
    14581 gatagcctct accatgacct gtggatagta ggtgtaagct gcaatgacac gctttcctaa
    14641 gtccagccaa tcctgatctg ttttttggcc attttttgca taggcctcta tcaagccatc
    14701 gtaagtatct agattaagct ctagtacatc taaagccttg ctgtaggcct caatctgttg
    14761 atcactgcca gcctcgtaga cattagcgat gagattataa taaagcgatt ccttgaactt
    14821 atcgtattgg tttaaggctg cttgcgccag cagcatatag ctagcgtttt tatgaatgtc
    14881 attgtaggat tttaggcccc agccaagcaa gagcctagcc tctgttgctg ttgtggttcc
    14941 ccaacgagaa taagagattg cccagcgatt accataaaca ttgtctctaa tatcccaaat
    15001 cccgttgccc tgatcatctt gacggtaaac caaataagcc tcgtggtcat tttggtaaat
    15061 attgaccgct ggaataccaa agacctcatt gactgctaca cctaaatttg ataatcccca
    15121 gcaaacagcc cctttttcca tcagcatcca gatccggtga cggttgtcat aagtaacatt
    15181 aaaggcatcg tcattgaggg tgccaacgag ctgatatttt tctgtccatt gagcttgatt
    15241 gtcagcgctg cgcatgtctg cgccaccgta gccgatgttt ttgtatttcg tataagagta
    15301 gccactggta tagctagcaa ccttatctcc atatttttgt tcggcgtaat gatgcagcca
    15361 gagaatttcc tcatcatcta ttttggcgtc cataacagca cgcaccaact ccatattgta
    15421 gttggcgaat tcttctttcc tcaagaattc gttgtctcga tacaattctt taaaggcttg
    15481 atatttcagc accgggtcag aagcaaggta ggtgccacca tagttaacca caaaggattt
    15541 gatctccttg cagtaggcaa cagcagttgc cagcatcatt tttttgtaga catagccatt
    15601 tcccttgtcc tccaaatctg ccttattagt agcataaagg tctcctaagg cgttcaaggt
    15661 ttttagggta gagccgttaa acatcgagcc tgcctctaaa aacagtgaca gagcgtcctc
    15721 atctgacaat agccaatcaa gagcgacctt gaccttttca tttttcttga cagcagattg
    15781 aatggtgtgg tagccgacac gattgacaaa ttcgcgctca agcactaatg ccaaattgtc
    15841 tggattatca taattatctg tgacactatt cttgctgaga agggcatcat actcttcagt
    15901 tgtctttagc ctgtcataag acacctcgct tgataaatca taatctgtct tgagcaacct
    15961 gagatccgca taaacagagt gatcattacc gttatttttt agtgaatttg caattagctt
    16021 tacatattta gcacctgtaa tatctagatc aacataaaca gcctcactgg ttccggttac
    16081 tgtaccagtt gtcaccaggc tttcccaact ttttccgtcc ttagacttat agatgttaaa
    16141 gctaacacca tcgtccttac cacgtctact atagtcaact cctaggtagg ctgatagacg
    16201 cgtgtattca ttggagtatt gttcaacatc ataataaagc tgtgaaggag catgcactgc
    16261 aattccctta tcaaatgcaa gcacctcgcc atcaactact agagtaatgg tgccaccggc
    16321 agggtttttg tcctgtaaaa agctgccatg cccaaccttg gacgggttga cacgtgtctc
    16381 atctgataag tagatatagt ccttagcttc agtcttattg gtggtctcta ctgcttgtga
    16441 tacttctgtc tgctcctgct ttgtggtctc ttcggcagaa gcttcggtag cttgctctgc
    16501 tgcggctact tgactcttag agtcagttgt ttctgtagtg gcagtaccta ttactactgg
    16561 cagcgtttct gaggagccct cagctgctgt gtcttgcgca gcggttgctg attggtcagc
    16621 tgcttgttga tcaaccgctt cttgtgcttc taacgtggtt gctatggctg cactagctgt
    16681 tacttgctgc tcatcagcag aaacagttgt cagccctagt gttaaaaata aggttgcaac
    16741 caacacagag gctgcacctg ttttaaaggt tttaatggca aagcgctgct taccatcagt
    16801 ataaggtttg aacatggtgt cttctccttt aaaaataaga tatttaagca aaataaagac
    16861 tgaccaccaa ccactacagt tgataatcag tccaacaaag atatcgtact ataggaaatt
    16921 aattaaaggg ggaaaatcat cgcctacagt taatttgatt ctttgcgtct tgacacaata
    16981 gcaagctggc ctgcacaagc aataactgca agagctgctg ctgtaaagaa tggattagct
    17041 gtatcagcag ttgccggaag cacttgctgc ttatcagctg ctttcttgtc ctccttctta
    17101 gcttcaggct tagattctgg tttaggctct ggcttaacct caggatctga tggttttact
    17161 ggatccgctg ggtcgattgg atcgaccggg tctaccggat ccactgggtc taccggatcc
    17221 actgggtcta ctgggtctac tggatccact gggtctaccg gatccactgg gtctaccgga
    17281 tctactgggt ctaccggatc cactgggtct actggatcta ctggatcgac cggtttagca
    17341 accaaggctg ccttggcatc tgagagggat ttcttagcat ttaacacctt aaccaagctg
    17401 ttagtaatag ctgtcggttc tgtctcctga gcataagctg tctcacccgc tgctgcgacc
    17461 tccttagcct tagctagctg gtctgtatag gcttgagcag aagctgctgt atatggagat
    17521 aggtctagat tttctccgat aagagcattt aattggtcta aagcagaacg caattttgcc
    17581 tttccttctt cggcaatcgc agcctttacc tttaaaatag tatcaacaac tgaatttgtt
    17641 tctgtagtgt agcgctctag ctcataaagg gaaatgtctt ttctctcttt atccttgtta
    17701 acagttctat agaaggtacc tgctgcttca atggccttat tgtacaattc cttcaaagac
    17761 tctgatgtca aagcaagatt tggattttct cggtaaagct ctaacagctt agccaaggct
    17821 tgatctaagg cttcatgcgc tacagcagtc ttaagcgtcg taagagcttg cgttaaatca
    17881 gtcgcagcct tatcaacatc tccttgtgaa ggaccaaatg aattttgaag cttagctgcc
    17941 gctgcaagct tttgcacaag accgtcatac gcttctttag gatactcttt gccatctgtt
    18001 ataaaaggtg tagcttgatt aatagcttca tttaaagcat taagattaac aagactagta
    18061 atagcggaat caatagtagt aacagattga tctactgtat tttgatcagg gtcactgttt
    18121 aaataggtct taccaatagt aaccgctgat tgcaaggctt gcagtgattc atcagaatac
    18181 gttccttcag gctggctgag ttttagctta gcctcctcta acgacttcct taactcagtt
    18241 ttattgctgt tggaattttt tagtttaaat gtgaagagct ttttggtatc atttttccca
    18301 tagaataccc aagctttaat agtataagat ccccccggta cagcatatgt aggcgaagct
    18361 aacatttcat cagttaaaaa ggaagtaccc gcagcattgt aaaagtcaaa ccatattttt
    18421 actccagggg tatcaattcc tcttgaacca tctccattcg aaataaagtc aaaagtatct
    18481 ccatcattaa cagtcccatt actaccttta cgagtaaccg taatttgact cataagatct
    18541 gagatagtaa ttggttctcc taattcaact gtatattctt gtggaatatc tatgtgccag
    18601 ttcagatgtt gacctgtccc attattttca aatgcactag cagtagtcgt ttccgcccct
    18661 actgttaaag cgctatcaat attatccgac aaggcaacca atcctgtgct gaaaactaat
    18721 ccaacaagac cacagccctt aagacaccgt ttcgtgaatt tcttcattct tctttttcct
    18781 tttctagagc cctagcaggc tcgaacaata gcaatatgtg tcatagggca gctgctatca
    18841 ctagtagctg ccactttgat attagcctga ttgtgacact caaatatcac ttataattta
    18901 caaaaaattt taagaaaagt caatatacaa acggtttttg ttaaattttt taaaaatata
    18961 acaaaaaaca agcacgccaa tctggtctat aacagttttt attgtcaata gtgatcgcta
    19021 aagggttttt cagccaacaa aaaaagagtg aatccctaac tctctcttct agactttgtg
    19081 ccatatcatc agctacacga acagccaaga tcaaaaaggc cagctctcaa tagtctgtgt
    19141 ccttaccctg cttcgtctga cagctagggc aaacaccata ggctataact ggaatacggg
    19201 tgaccttata gcctgtttgc tggtgtgctt ccttagcgat atccatcaca tctacgtcca
    19261 taaaatcagc gattgtcccg caaacctcac aaaccacatt gacatgctga tgtcccataa
    19321 agtcataata ggtcgtcaaa tcattactaa ttttcagctc ggatacaaag ccctcatcaa
    19381 cgagaacctt caaattatta tacaccgtag caaggctcat attagggtat tgaggctgta
    19441 aatcacgata gattttatct gcgctggggt gctcagtgga ctgaatcatg taagaaatga
    19501 tcgccttacg cgtctcggta atacgaatat gcttgtcacg tagatgctct aggacatttt
    19561 cataggcatt tagagcttgc tgatgtgaat gaatgtccaa gcttacaacc tcctcctttt
    19621 gtaactatgg cactaactag caggaatctt gatcctgctt gctgattagc cgtaaatagt
    19681 caatcttgat acagcgattc ataacaatgt cagctttgcc tgctgatcgc aaaagctcct
    19741 cagcttcttg gctatacaag ccaagctgtg cccaaaagac ctgaccctga caagctaaaa
    19801 agtcctgagc aacctgaggc aaatactcac ttcgtcgaaa gacattggca atatctacct
    19861 taaaaggaat agccgcaagg ctagcataaa cgacctctcc taaaacagac tgacctgcca
    19921 gcctaggatt gacagggaca atccgatagc ccttagcctg cataaaccta gccacatcat
    19981 aagcagcagt ggtttgacga tcagataagc caaccactgc aatggtcttg gaagattcaa
    20041 gataagaggt gatagtctca tcagagggat tttgaaatgt atcaatcatc atttacttcc
    20101 tttttatcaa gcacacccaa tagcaaatca acaacaggaa aagacaatcg ctgccggtat
    20161 gacatagcca accatctggc taccaagctc aaggaaaacc ctccttagca tgacatgccc
    20221 tgctgttttt ttctcttcat tatagcataa gtttttaaaa tgcggaacac aaggaataac
    20281 agcagccaca ccaagcaggc tgccacttaa caccactgct aatctagtct acttggcctc
    20341 ataccagctc ttgccggcac tttcgtctac acgcagcgga actgccaggc tgacagctga
    20401 ttccatcgtt tctttgacca gcgctttaac agccgctagc tcatgattag gcacctcaag
    20461 cacaatctca tcatgcacct gaagcagcat tttggtctca aagccaccag ctactagggc
    20521 ttggtcaaga tttatcatcg caattttgag aatatcggct gcactgcctt gaatgggcga
    20581 attaatggct gtacgctctg caaaggagcg aacgttgaac tgacgagaat tgatatctgg
    20641 caattgacga cggcgcttaa agagcgtctc aacatagccc ttatccttgg cttcacgcac
    20701 aaccctttcc atgtaagcct tgataccagg gtagcgctca aagtaggtgt caatataagc
    20761 cttggcctgt tttcttggaa ttccaaggtt attagacaag ccaaagtcag aaatcccata
    20821 cacaatgcca aagttaacag ccttagcatt ccgacgatca ttggcagtga cgtcctctgg
    20881 cttttcaatg ccaaagacac gcattgccgt tgaggtatgg atatccgctc cctccttaaa
    20941 agcagcaatc aaatgctcat ctcctgaaat atgtgctaaa acacgcaatt caatttgcga
    21001 ataatccgag ctaagcaaaa cagcatcatc atgagatgga gtaaaggcct tacgaatcaa
    21061 gcgcccctgc tccagacgaa tcgggatatt ttgcaggtta ggatcaacac tggaaagtcg
    21121 gcctgtctgg gttaaatcct gtaaatagcg ggtgtggatc ctgccatcag ccatgatgta
    21181 atcctgcagt ccaatcacat aggttgattg cagcttagta atttgacgat agtccaagat
    21241 cttagccacg attggcgcaa ttggcgctaa gcgctccaag acatcaacag ccgttgaata
    21301 gcctgtcttg gttttctttg tcaaatgaag agggagctgc attttctcaa agagtatcac
    21361 tcctagctgc ttgggagaat taatattaaa gacctcacca gccatttcat agatttcctg
    21421 tgtcagttcc tcaatgacca ccttattttg ctctgccatt tcctgcaggc tatcttgatt
    21481 gacagcaatg ccttcgattt ccattttcgc aaggacattg gcaagcggca gttcaatgtc
    21541 agtgtagaga tcagcctgct catgctctgc cagcttatca agcatgactg gtctactatc
    21601 cagcaagacc tgaaccttac gcgccagatg tcctaacaaa acagccttgt caggcacagc
    21661 acgcttgacc cccttaccat agacaacctc atctgtatcc agtgatatag tggtataaag
    21721 acgtgccaga gtagccatct cattgtcctc tacagttgac aagaggtaat tagctaagcg
    21781 ggcatcatag ctggcagccg gcaaatcaag ccccagatga ctaagcagaa ccttactgcg
    21841 cttaaaatca taggtagcaa tcggctgctc aagaaccttt ttaaagagct ttgtagtgag
    21901 gagactaata tctgctgaag cataaatctg gccttggttg ccccaagcaa agccaatcag
    21961 ctcctcgcgg tgataattat ccctcaaagc ttcaaaataa aacaccgtat cgtctgaaaa
    22021 catgtccgct cttatgtcag taacttcctg ataagcaatc tcagctaccg gctcctgtgg
    22081 caactgacta gctaaggcat tttttagttg aacaaaatcc atctcatcat aaaattgtga
    22141 caagcgatct agatctggac cctgatagac aatatcctcc aatccaatcg taatcggagc
    22201 gctagtgttg atagtagcaa gtgtctttga gaggaaggcc tgctccttat catgaagcag
    22261 gttttccttc atttttgaag gcttgaagct atcaatatgc tcgtaaatcc cctccaagct
    22321 tccatattcg tgcaggagct ttagacctgt tttttcccca attttggtca ctcctggaat
    22381 attatcagac ttgtctccca tgagcgcttt caagtcaatg aattgctctg gcgtaagccc
    22441 cattttgtcc ataaggtagg ctggggtaaa ctcttcaaat tcagcaactc cttttttaga
    22501 aatctcaaca acggtatttg catctgtcag ctgaatcaaa tccttgtcac cactgacaat
    22561 agtcacatca aaaggaatct ctgtacgctc tgccatttta tcaagcgttc cgataatatc
    22621 gtctgcctcg taatgctcta gctcataaaa ggcaatacca agcgctccca gcatatcacg
    22681 aatataagga aactgctccc gaaattcatc aggggtcttg gcacgtcctg ccttgtaatc
    22741 agcaaaaagc tctgtccgaa aggttgtttt acccgcgtca aaggccacca agacatgcgt
    22801 cggctgaaca cgcttcatca tgtggtctag catcaaatga aagccataaa tcgcattagt
    22861 gtgaagaccg ctgtgatttt taaagcggtc aatctggtta tagagggcaa aaaaggcacg
    22921 aaaggccact gaggagccat caatcaaaag taatttattc ttgttttcca tgcctttatt
    22981 ataccacaca gtgacctgct ttgctctgac cagctacgct ttttgcaagc actagcaggt
    23041 aaagcagcat acccgtagct tgatcaaaag atccaagctg cttgaaggaa gataaatgac
    23101 tgcttttgct ttatcatcaa gacatttcta ccaaaaaaga gactgagata aaaagagtga
    23161 cactttagag agtcttaact aatatccttt gttatctaat tcattaacaa acgaacaggc
    23221 ctagttttca aaacctcaga aaactaaacc tgttcatttg ttctatttga agtcagactt
    23281 tgtctcaatc tccaaattga tgacatcatc tgctatgact ttcctaagct gatatggacg
    23341 gaaagccttc tgcaaaatcc atgattagtc taggctacat ttgagcgagc ggccttatga
    23401 ctgagtccat ttggccacct tatcagcatg gctagccacc catttcttgg ctgcggcttc
    23461 tggtgtcatg ccctgattga tgtcaagcat aacagcctcc atatcctctt tttcccaatg
    23521 gaagtgatca acaatcctat gaacagctgg caggtcggcc tttaagcccc gacgtgcaat
    23581 ggtattgata ttttcctttg agccaaaggt tttctttgga tctgccaggt atttcaaatc
    23641 gtacttagca aacatccaat gaggagacca agccgtcaca acgatcggct cctttttctt
    23701 gaccgcctga tcaagtgagg tggtcatagc acctgtcgaa gcagcaacga gctcccaatc
    23761 tgccaagttg gaataggcct tttgcgtctt atcagcagca gtcataatac cagctcccgg
    23821 ttcaatccca ataatctgtt gattggcttg atccgaaagc tcctctatgc tgttcacatc
    23881 gctcatatag gctggcacag cgagtcctag ctttgttccc ttcagattag gaccaagatt
    23941 atccagctta tcctgatact tttggtactg ctgctgatgg gtcactggta accaggcact
    24001 tgttgaaaag tctgcatcgc catttgcgat ggtttgccac atcacagcat tatccagtgg
    24061 tgtcaaggtt acctgataac cctcatctct taagacctga gcgataacat gggtagaagc
    24121 cacctcagaa tcccactgca cataagcaat ggtcaccttc tgccccttgt ctgctgagct
    24181 tgataacatc gcagcaaagc cacgccccaa agctgacaac aaaaagacag ctaaagcagc
    24241 tagaccaagc catttcttgg tttttccagt ctgcgttctt tcttgcggct taccgttaaa
    24301 atgctgagtc atacgatcca aaataatcgc caagataaca agggccaaac cactaacaaa
    24361 gccacgccca atatcagcat gctgcaaggc cgataggacc tcacgtccaa gacctggagc
    24421 accaatcatt gagcctgtca caaccattga tagggccaac atcatggtct gattaacacc
    24481 tgccatcatc gtatgctttg ccaagggtaa ttcgaccttc agtaattttt gtttaggggt
    24541 tgacccaaag gcatctgaag cttcaaccaa ttctgtcgga atatgacgaa gcgctaaatt
    24601 ggtaaaacga acagtcggcg gcaaggcaaa gataaccgac gcaaagacgc cagggaccat
    24661 accaatgcca aaaaaggcga cagccggaat caaataaaca aaggctggca tggtctgcat
    24721 aaggtccagc attggattaa tcacctggtg aacaatctta tttttagcca tccaaatgcc
    24781 caagggaata ccaagcaaga cagagatgag gcttgctacc aaaaccagcg taaaggtatt
    24841 gatcagctct gcccacaggc cttggttata gacaaataac aggcccagga gggtaaagat
    24901 cggcaaaggc catttttttc ttgccaagaa aaacatcgca caggtaacca atagcataaa
    24961 cagtaacgga ttgataaaca aaagggtctg cgtgatccaa tccatcaaag cattgcccac
    25021 aagctgcagc agatcaaaga agcctgaaaa ggtttttgtc agccactcag ttagttgctc
    25081 aaccagctgt gccactggta gagttgtttg taataggttt tccaaaatac agtctctcca
    25141 ttctaattaa ggtcgtcatc tggaatatta gccaaggctt caaggacacg cccacgaata
    25201 ataaccccta acaagcggtg ctgctcatct gtcactgcaa ttggcgcaga agagtcataa
    25261 atcaagggca aaatatccgt aataacagta tcctttgaga ccgttctgac attacgatca
    25321 ataacctctg acaaggggag ctttttctga cgtgcttcaa tcgctccgtc tgctgttagg
    25381 cttcctatta gctgacgacg acgattggtt gccatgagca tagacacctc ctcattgtgc
    25441 atacgattca aagccacctg cggaccgtcc agatcaaccg ttgttgtgat aggcttaatc
    25501 ataatatgct gagcagtcag cacctttgag cggtcaacgt cctctacaaa ttcacgaaca
    25561 aaatcattag ccggattggt tagaatatcc tcacccgtcc caatctgcat gatctgaccg
    25621 tccttcatca aggcaatacg atcaccaata cgcagagcct cattcaagtc gtgactgata
    25681 aaaataatgg tctgcttcat cgtctcctgt aattctagca gctcatcttg catgtcacga
    25741 cgaatcaagg gatctaaggc agaaaaagcc tcgtccatca gcaaaatctt agggctgttt
    25801 gccaaggcac gcgccaagcc aacacgctgc tgcatgccac cagacaattg atcagggtat
    25861 tggtccctga cctcaagaag ccctgactga tcaagcgcac gctttgcaat ctctcgacgc
    25921 tcctgctttg gtaccccacg cagctccaag ccaaactctg tgttttccaa aatcgtcttg
    25981 tgtggaaaaa gagcaaagct ttgaaaaacc atattcatat catgcctgcg aacttctctg
    26041 agctgatcca cagacagttt agaaatatcc cttccctcta ataaaataga gcctgctgag
    26101 ggctcaatta atcgattaag catacgaaca agcgttgatt tgccgctgcc tgaaaggccc
    26161 atgatcacaa aaatctcgcc ttcctgaacc tcaaagctgg catcatagac cccgacagta
    26221 actcctgtct ttttaaaaat agcgctctta cttttaccag ccttgatcat ttcaagagct
    26281 gctttttgtt ttttgccaaa caatttactc aaatgcctga cctctaaaat agttcccatt
    26341 cttttcctct cttgttctct tcctcgatta aagctaaatt agcttaatag atttctaaaa
    26401 gtgccaccac aattttaaaa taatgaggtc actttttgct taaaaaaaga gtctgcctaa
    26461 acagaacaca ttaattatat aatatatggt cactttttgt caagctggac gcttgctacc
    26521 caagtatcag gatcgtccta agcagtgata tcactagtca accaagcact taacagccct
    26581 gaacagacca cagcaagcag gcctttctga cacttagcgc cttgagagct tacccagcag
    26641 cctcctctag ctgacttgat tgacctatct gactcttgtc ctgcaaccaa accaatgctt
    26701 agactgccaa gcaagctccc aatagcaata agatctgcta agcaaagcgt tagcttgctt
    26761 tgaccatagc tgctagtcat gtctaatagc actctagata aatcaaaagc cccacctagc
    26821 aaggctagat gaggcaaaat aggtttagag aagggcttta aactgaatat ttgagtcttc
    26881 caagaagcag tcgtcaaagc cacgtgggtg atgatactcg atgcgatcct gatcctgtgg
    26941 ataggtgtat ttgccaccaa cctcccaaat gaatggatgg aattggtatt gcaagcgctc
    27001 cttacgcatc ttccaaagct ctaggatttc atcagttgag gccatgaagt ttgaccagat
    27061 atcatagtga accggaatga caaccttggc gcggagattt tctgccatac gaagtaggtc
    27121 aacagaggtc atcttatcct gaataccgat tggattttca ccataattgt tcaagacaac
    27181 atcaatatcg tagtcacgtc catgcttagc aaaatagttt gagaagtggg agtctgcacc
    27241 atgatagatg gttcctcctg gtgtttcaaa aatgtagtta acggttttgc gagctaactc
    27301 ttcgtcagtc actggaagtc ctgctagctc gccaccattt tcctcagcgc cagcaactgg
    27361 taaggtaacg atacaggtac ggtcaaagga ttcaacagca gtaaccttga tatccttgaa
    27421 tgcaaagcta tcgcctggtt ttaccacgat gatacgatcc tttggaacac cccagctctc
    27481 ccaaatcttg ccgcactcat aagggccaac aaatttgaca tggtcaagct ttggattgtt
    27541 gataatggct gctgcagtat tgatatcaat gtggtcacta tgataatgag acaccaagta
    27601 atagtctaac tcattaatca taaagggatc aataaccatt ggctgagctc ttagatttgg
    27661 ttgtagcttg cgaacccctg ccatattggc catttggtga ccacgaacca tgtcttttac
    27721 ttttttagtt gcctttccac gattggacca taggtccatg acaacattgg caccacccgg
    27781 tgttttgatc cagataccgc agttacctag ccaccacata gagaaatttc cttcaggcac
    27841 tacctcttct tcaatttctt cgtttagcca ggttccccat tctgggaagg tgctaagaat
    27901 ccatgattca cgagttatat cttgtacttt agccattatg tttcctccaa aatgaatttt
    27961 tatctatact ctaagtatag accttcttta ttctcataaa aagaccaagt gtcacacact
    28021 cttgtgttca aaactggact gaattttggc tcaaaataaa ctaaaagccc cagccttctc
    28081 ctaaaccaat agacagctga ggggtcctta tcaataggca agctagtagc ttacaataat
    28141 tcgtgatgaa tgagcttttc aatttttgtt ttcaaggcat agcggtcagc atcgtcctta
    28201 acaatggtct cgatcgcctt ttctagctca agggaaaaac gagagctatc actcaagcgc
    28261 ccctgctttg aaaaacggat caatctaata atgtcatcat cgctcaaaat aggattgaca
    28321 atcagtacgg gaacaagagc ctccagtgcg tctgttgttg ataccacaat gtcaacagac
    28381 atcaaatcaa agacactctg gtattgctct gttgtaaaga cagcctcgat ttgacaattg
    28441 ggcaaataac gctggcactg cttcaacagc agcttttgaa tcccaatgcc atcatctgaa
    28501 acgataacaa gcttggtctt gtcccagtca gcatgactat ggcgcagctc tcctcccaga
    28561 tgaatcgtta gataagccac gtcatcatct gttagacgga tctgccaagc ctgctctagg
    28621 attacagcac aggattgagc catagcaaag agctcctcgt atttttcctt aatatggtct
    28681 gttaaaggat tgatcgaaaa aatcccatag gcctttcgat aaacaagggc cttgcaatgc
    28741 ctggtcagct gtctaagcaa gtcctttttg tgggtaaaat gcagctgata gcgcagctcc
    28801 agctgatcga taaaatcacc aatagtggct cgcatctgct cataatcctg actttcaaca
    28861 tggtgatcct gatcttttct aaaggatagc atcagcatgg ctatcatgcc tacctcaatg
    28921 tcatctaaat gcagcttgaa attgtggtaa agctcactag ccaatgcctt agcaatctgg
    28981 tattccttgc gcttccaaat caggttaaaa tcccttttaa gcgctgtttt agtttccgaa
    29041 tgcaattgca tgttgcgata gctaagcagg ataaaaggaa gaatttgcag cataaactga
    29101 ctatcctgaa tattaattgt tttgcctagg ctagcctgag acaaaaagag gtattcgtga
    29161 aaataatcca aaacctcctt tgaaaaataa gctgacaagc cttgtgtctc agaaagctta
    29221 tgatcaaaaa gctcaataaa gctgctattg cctccctgat aaacacctgc caataccttg
    29281 taaaggtact gaatcaaagc catagggtga cagtcaaagt aatagccctt ggccttggtg
    29341 gcatgcagct gaatcttatt gttatagcta gacaattcct ctctcagttc agcaaggtca
    29401 tttaagatgg tatttctgga aacatcatta atcatcatga gcttatccag tgtcacccgc
    29461 tctgttgcca ctgcaatata aatcgctgat aagctcctgc gctcatcacc cttcatgaca
    29521 tagtgataat ctgccacttc attgaggagc tgttggcagg cagccttttg ctcactattt
    29581 agcaagatgc caacccgagg ataggagaca atttgagcaa catggctggg cagcgcttcg
    29641 ttaattttat ccaaatgata atagattttg cgccgcgact gacccaaggc agctgaaatc
    29701 gccatgactg tctcagcctc cttcaatcga atcagatatg acagcagatc atagcttttt
    29761 ttatccaaaa taatcacgtt catacctccc ttctataaaa catcactacc acacagcctt
    29821 atcagtttac cattttacct atctgtagga aagaatacta ggccaaagtc aatttctaaa
    29881 taggaaaaaa cgaacgatca ttagttttct gaagataaaa ttcctaatta gttcgctttt
    29941 ttcttttata attgtaatag ttgaattaat tattaaactt tgtctaaaat aagaggcttt
    30001 ttatcccaga ttgcaacaag ggttaacacc ttgaccttaa gcctagctaa gcagctctca
    30061 ctaagttact agctgctgcc ttaatgccgg ctaccttttt ggccataata ggcatttgga
    30121 ccatgctttc taaggtaatg cttgtccata atataggttg gagctggctc cacacgagga
    30181 ttgatttgtt ctgtcaggcg gttcatcttg gccacctctt cgagcaccac tgagtgataa
    30241 accgctaatt caggcgtctt gccccaagta aagggaccat gattgcgaac aacaatacca
    30301 ggcactgcca tcggatcaag accacgacta gcaaattcct ctaaaataac cgtacccgtt
    30361 tctttttcat aggctccatt aacctcatcg gcagttagag agcgagcaca tggaatgggg
    30421 ccataaaagt aatcagcatg agttgtccca taaaatggaa tatctcgccc agcctgtgcc
    30481 cagccaaccg cttctgttga gtgtgtgtgc acaatcccgc caacctctgg ccatgccttg
    30541 tataattgca catgggttgg caaatcagaa gaagggttca gctctccctc aacaatagtg
    30601 ccatctaagt ctgtaacgac catattttcc ggtgttaatt ggtcatagtc aacgccgctt
    30661 ggcttgatga cgatacgtcc cagctcacga cagacctctg agacattgcc ccaggtaaat
    30721 ttcaccagcc catgcagcgg tagggccttg ttggctgcac agacacgttc acgcatttct
    30781 tgtagccttt ttgccattag cttaaccccg ctttctcaat cagtggataa aggaaatcct
    30841 gtgcctcctt gatggcagct cttgtctcct ctacagtttc acagttttct gaccacattt
    30901 caatcaaaaa tggaccatga taatgcgttt tcttgagcac atcaaacatt gcttcccaat
    30961 caacacagcc ttgaccgaat ggcacatcac gaaattgccc tttagatgtt tctgtcacag
    31021 cataggtgtc ctttagatgc aaggcagcaa tagaccgatg cccattgtaa aattcactcc
    31081 agaggtcatt atgccaagca gagacattgc ccgtatctgg atagacaaag agataagggg
    31141 agtcaatttc tttttccaca gctaggtatt tctcaattga gttgataaaa ggatcgtcca
    31201 ttatttcaat ggctaaaata acctgagctt cctctgccca agtgcaggcc tgtctgagat
    31261 ttttgataaa gcgcgcacgc gtttcaggtg atttttcttc ataataaacg tcatagccag
    31321 ccaattgaat ggtacgcaca ccaagatcct gtgctagcac aatgcatttt ttcattagct
    31381 ctaatgatgt cgcttctgtt tctggattgc tagagccaag tggataacga cgatgaccag
    31441 agaagcaaat gcttgggata cgaacccctg tttcataaat agccttgaca atgtctagtc
    31501 gctcctgttt actccaatcc aagcgcgcta ggcgagcatc tgattcatcg acagacattt
    31561 ctacaaaatc aaagcctaat acctttgcaa attgcaagcg ttccagccaa gtaaaatgct
    31621 ttggcgttgc tttttcatat ataccaatag gacgcgccat attgttaccc ccaaatgcgt
    31681 cgaatctcgt ctttaaaggc acgtgccgct gctgcaggat cctctgcttc agtgatacca
    31741 cgacctgcaa taaaggtaaa gacattaacc ccttcaaaga gcttgagggt attgatatct
    31801 aagccacccg tcaccgatac acgaaagccc atgtcaatga gggctttgac cttgttcaga
    31861 tctttttcac cccatacttc accagcgagt agggcgtcac gtgattgatg gtaaatcgcc
    31921 tgtgaaatgc ctgcatctag ccacaattgt gcctgttcat aggtccaatc accatacagc
    31981 tcaacctgaa tctcgccacg ttccccacgc tcttctttga tggctttcag tgcggctgcc
    32041 atggttggaa tagtggcaca gcaaatacaa gtcatccagt ccgcaccacg cttagcatta
    32101 ttcttagcaa cagtaccgcc agcgtctgca cacttggtgt ctgctacgat gatcttctct
    32161 ggaaataagc tacgcagcac ctcaaccaat tcgctgccta cttgaagcag gcaaactgtc
    32221 cctgcttcga ttacatcaac ctcgtgacca actgcaacag cagccctgac cgccccctgc
    32281 aaatcagaat gatctaaggc aacctgtaat tttggaatat gtgtcatgat tttctaccaa
    32341 gagcccgtag caccgccttc aatgcttaat agcgagctcc tatcctttct gttgtgtttg
    32401 attcgtttag tgatgatggc ttgtctaaga atccaaatcc aagccctcta aataaggact
    32461 atttttggac tcgtccacca aagccaaaac ctctgctgga gtgtgacagg caactaagcg
    32521 cgaaatagcg tcttccagtt caaaaagggc gacaatctgt ggaatagcaa ctgttgtatg
    32581 aatagaagga tcagttgccg ccaaggttag caataccgaa gcctctttgc catctgaaaa
    32641 ggtcaccggc ttggtcagtg tgataagagc aaaggcattt cgcttgaccc ctacaccagc
    32701 ctctgcgtgt ggcatggcca ttcccggcat aaggacataa tagggcccgt acttttctgt
    32761 tgatgcgata atagcgtcat aatattcaga ggtcaccgcc ccgctgtcaa tcaaaggctg
    32821 aacagctagc ttaaccgctt cctgccagct agctgctgac aagcccaagc gaatagagtt
    32881 gttttcgata aatgcttttt ttaaattcat ataactatcc tttctaaatc aaattctttg
    32941 gccagacact ttttgcctca ctcctatcta gctgataaag agaaagagct ggaatctctc
    33001 ttcacaactc tcactccatc tatccttact gaaagttgat tgctacagct tagcttacag
    33061 ccaagtggct gctcttaggc tcactatcat ttgccatgag cagcactgat gtcatcaggg
    33121 ccgctctaaa gcaccgcctg tagcttggtt ttgatttcat tgtcgtccat aagattatct
    33181 agtccaacca aatgaccctt tgtacgccca tctaattcat gaatcaggtg attagaagca
    33241 accacaatat catagcctga ggcaagtccc tttgcctcac ccactgagca agaagcagac
    33301 tgaatatcag tcaccccaag ctgacgaagt gcgttttcaa ccttcatttt aataaccatt
    33361 gatgacccca tgccattacc gcatgctgta agaaccttaa ccatttattt tcctccgaat
    33421 atatgataat ttgatatgaa tgaagacctg cagaagtata tcgacaaact cctaccagcc
    33481 tgtgctaaaa gacgaataag cagctattat caccttgctt attgtgcttc accgcggtag
    33541 taagcctctt tatccttagc cctagcaaat tgtagctgtg gaatagcaag taagaagaca
    33601 cacaccacca catagcctgc aataccaagg aacttgaaga gataaccaaa tggaagccaa
    33661 ggaagcacca ggtcaatatt gccatgataa ccacctgtca agcccaacag accaactgcc
    33721 actgcaccta aggcaacctg aagaatacct gatataaagg atagagcaac agctgccttc
    33781 cagccaccac gcttatctgc ataaacagca atcgcagcat tatcaaagaa gaccggaaca
    33841 aatcctgtga tgatcaagat tggattttta aagatcacaa gaagtgcaat agtgattagc
    33901 tgaccgataa gcccaaaggt aaatcctgac aaaacagcgt ttgaagagcc aaagccatat
    33961 gacgctgcaa cgtccaccgc aggaaatgaa cccggaagga gcttacttga aatcccttgg
    34021 aaggcattgg tcaactctga cacaaacata cgcacaccct gcatcaggat aaagagataa
    34081 actgagaaag ttaaggaggt ttgcaaaata tacataaaga aggcctgctt agctggatta
    34141 aaggcaccag cacctataag ttctgcatta gacatcatat ctgggccaag cacagccaag
    34201 atagcaccaa agaaaaccag cattagagtg gcagaagcaa ccaccgtatc atgaaaaatc
    34261 gttaaaaagc ttgctagctt aagattgtca aggttctctt cttttttacc aaagaaaggc
    34321 gccaccttgt caacaaacca gatcgcaaac tgctgctggt gcccaatggc aaagcctcca
    34381 ccacctgtca agcgctgagt cgcctcaact gtcatattgg agctgacagc ccagtaaagg
    34441 ccacagataa taccgaccgc ccaagcacca aaagcatttt gaagctgagg gattaaaaga
    34501 agaacaaaca cagagatggt tgccgcctgc tgcaccatga tatgacccgt aataaagagc
    34561 gtacgaacct ttgtcacctt acgaagcgcc actagcaaaa tattgacccc aaaaccgatc
    34621 aaaagggctg tggtggcaac gctgatggat cccatctcct ctagcttggt attggctgct
    34681 gcaagtccaa agtaagggtc aataactgcg gcctttaatt caaatttctt acccaatgcc
    34741 actaggattg ggcgaaaggt gttaaccaag cccccagcac caacattcaa aatcagataa
    34801 ccaaccgttg ccttaacaaa gccagcaaat acttcatgca ggggcttttt aagcagcaaa
    34861 tacccaatca aaaccaaaag acctacaaag aaagccggat tttgcaaaat atcttgcgaa
    34921 aaccagttta ggggagctat aagcattttc ataagaacta cctcttttca cagttaataa
    34981 atatgatatt ttctatacaa taattgtaaa cgatgtaagc gtttaaaaaa aagaccaaca
    35041 atcacacaaa gaagtgttca aaaatgtact gaagccaatt tccagctagc tctgatcact
    35101 gttaaagcac tatcattaat ctctaattaa taaccaaaca catcacaaca atatcgggct
    35161 aacacaaaaa taggccagcc catactgccc agccaaaacg aaacaagcaa tcaattcaag
    35221 gcacttaacc ctgttttata tcgtacaaag cccttttaag atgattttgt ttgtttccta
    35281 atcgtaaatt agttatctga tccgttctct cctcagatat actcaccctt atctaattct
    35341 actgtcaaat agctacttac tcataagcaa atgaatatta agcaaccacc aagctacaat
    35401 aaaagacctt accctgttgg caagatctta ttcattatac aatttttcct tctgcgacat
    35461 ggactacctc atcacacaag tcttcaatat ctgtcttcag atgtgagctt aaaatcacaa
    35521 gcccattttt gctaacatct aaaagcaatt ttttcgtttg ctccacgctc ctgtcatcta
    35581 atgcattcat tggctcatct aatataagga tcttagggtg atgcatcaag gcctgaatta
    35641 accctaattt tttcttagtg cctagcgatt aatgcttaaa tgctgtttga ctaaactgat
    35701 gtaaatgata aacatctaac caaaaagcta aatcaatatc tctagcctta ggagagattg
    35761 acctaagcaa ctctagattt tgtaacaatg ttaaatgtgc aataaactct ggattctcaa
    35821 tcaaaatccc agcatcctcg atataattat ggtactgtct aattttttta ttgtcctgat
    35881 aaacagctcc ttcatctaat ttgatataac cagctaaggc cttaagtatc aaggtttttc
    35941 ccgaaccatt aatacctacc aaaccataga tattaccttc tttaaaagta agattaatat
    36001 catctagaac aaggttaccc ttatacagtt ttctaccatg ttcaatccgt aacatctcag
    36061 ctctccttat aataattgtc ataaagcata tgtaccaata ctattagcag caggcaccac
    36121 caaacatcaa acaaaaagta acgtatcaag gtgagactag caaacaagat catagctact
    36181 acagcagatg aggcatagcg tatcataaca taaatcaagc aaatatctat agtaagccaa
    36241 gataccataa gataacatag tcgttcaata tgatatggtg caccataata ggtcatcaat
    36301 acacctaata ttaaaacgat aaaaagtaac cactctttaa tatagaaaat cgtactcgtc
    36361 cgccatagct tgttaaaaaa taccaactga cttcgagcat gaaaacgaaa gatttcctta
    36421 gttccttcag ccaaatccgc caaaaatgaa atcgtaaaat aaaagctgtt gaaggacaag
    36481 cctagcaagg tgataacctt gacaaaatca gctgtctccc cttcaatcac tggaaacggc
    36541 attagcaacc gatagcacac taaattatga aaatctcgct ccccagtcat attagcctta
    36601 atcaataaaa gatgtattag taagccagta agacatgctt tcattccaac aaccagcagg
    36661 ttagataatt tcatggtgct tcctcaattt taaaacgatg cacacaccca ctaagcctaa
    36721 ataaggtgat aaaaggtaag gaatatcagc atcactataa gatgttgaca tcaaagaagt
    36781 cataagaaca tatttgggag gtaaatagct atataacaac ggtgacaaag cccacatcaa
    36841 aatcaaatag agcatgcttg acttaataaa ggattgaaga tagtcaacaa gaaaacaaac
    36901 gaaatacgta tgaacgaaca aagctaacga ttttactaag caatagtaag ctataaaggt
    36961 tgttgctcct tgaccaaaaa aacgcaatat tgagttttga tcaaaataag gcattaaatt
    37021 accgttcata tgggcaacac catttagcca agacactaaa gtcaaagcaa atattacaat
    37081 gtaaaaactc agtaaaacat ataagctcaa ctgaagcttt aaaaaaatac accttttacc
    37141 atagtcagac tttctgccaa tgaggtattt aagatgtctt gacttaaggt aatagtaggc
    37201 ataggccact aaaatcatca ctagtggata gataaaagat tgataaaaac taaaatcaaa
    37261 caccacacta tccaaacgta tcatactcaa caatagactt ttctttacct caattccacc
    37321 agataaatct actgcacttg tatcaaaaaa taagatatgc ttcaaactgt caaaataaat
    37381 aaaacctaaa aatagtaacg ggactaatgg ataaaaatag cgaaatggaa ataatctata
    37441 ctgtagcatt tatgaataac tcccctacaa aaaatcaagg aaacgcctcg ttactaactc
    37501 aattcacaat tgtagatatt taccaattgt ctggagacca actaccacta atggttgttg
    37561 ctccgtccca ccaattttca cgtaccagat gcaaggcata aaggtaccca cttttagtat
    37621 cctgtgtata aattcctctg tcgcctgtcc aagttttatc tatatcactt cttctttgac
    37681 cgttactatt agctagatag tgccttacca caatttctct attacgtcct cttgaatcta
    37741 aattaacgac ataataaggc gccgcactct tcacaagata atctttcgtc cttccaaaag
    37801 atgacgtgat tctaaaattt tgcaagtaac caatttgtcg ttctgctata actaaagaac
    37861 taatcaataa tgtagaagct acaattgcca ataatccaat cttaattttg cctaatttta
    37921 ttttttaata atttataatt tttatatatt tagcacatca tcagcgcttc cttgacaatt
    37981 gataatacaa ttcatgctag gcttaatcg
//
LOCUS       DARYXZ010000020        36414 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYXZ010000020 DARYXZ010000000
VERSION     DARYXZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36414
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            82..155
                     /locus_tag="TV186_000873"
     tRNA            82..155
                     /locus_tag="TV186_000873"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:116..118,aa:Met,seq:cat)
     gene            180..252
                     /locus_tag="TV186_000874"
     tRNA            180..252
                     /locus_tag="TV186_000874"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:213..215,aa:Phe,seq:gaa)
     gene            258..328
                     /locus_tag="TV186_000875"
     tRNA            258..328
                     /locus_tag="TV186_000875"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:290..292,aa:Gly,seq:tcc)
     gene            358..431
                     /locus_tag="TV186_000876"
     tRNA            358..431
                     /locus_tag="TV186_000876"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Ile,seq:gat)
     gene            441..528
                     /locus_tag="TV186_000877"
     tRNA            441..528
                     /locus_tag="TV186_000877"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:475..477,aa:Ser,seq:gct)
     gene            587..1402
                     /locus_tag="TV186_000878"
     CDS             587..1402
                     /locus_tag="TV186_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL1532284.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            1405..1908
                     /gene="mreD"
                     /locus_tag="TV186_000879"
     CDS             1405..1908
                     /gene="mreD"
                     /locus_tag="TV186_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL1532285.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            2004..3182
                     /locus_tag="TV186_000880"
     CDS             2004..3182
                     /locus_tag="TV186_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1532286.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            3287..4249
                     /locus_tag="TV186_000881"
     CDS             3287..4249
                     /locus_tag="TV186_000881"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1532287.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            4609..5379
                     /gene="recO"
                     /locus_tag="TV186_000882"
     CDS             4609..5379
                     /gene="recO"
                     /locus_tag="TV186_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL1532288.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            5495..6502
                     /gene="plsX"
                     /locus_tag="TV186_000883"
     CDS             5495..6502
                     /gene="plsX"
                     /locus_tag="TV186_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL1532289.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            6495..6743
                     /locus_tag="TV186_000884"
     CDS             6495..6743
                     /locus_tag="TV186_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1532290.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            6893..7603
                     /locus_tag="TV186_000885"
     CDS             6893..7603
                     /locus_tag="TV186_000885"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL1532291.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            7782..11522
                     /locus_tag="TV186_000886"
     CDS             7782..11522
                     /locus_tag="TV186_000886"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL1532292.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAENLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            11641..13098
                     /locus_tag="TV186_000887"
     CDS             11641..13098
                     /locus_tag="TV186_000887"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL1532293.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            13155..14177
                     /locus_tag="TV186_000888"
     CDS             13155..14177
                     /locus_tag="TV186_000888"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL1532294.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            14174..14731
                     /gene="purN"
                     /locus_tag="TV186_000889"
     CDS             14174..14731
                     /gene="purN"
                     /locus_tag="TV186_000889"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL1532295.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            14878..16425
                     /gene="purH"
                     /locus_tag="TV186_000890"
     CDS             14878..16425
                     /gene="purH"
                     /locus_tag="TV186_000890"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL1532296.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(16803..17957)
                     /locus_tag="TV186_000891"
     CDS             complement(16803..17957)
                     /locus_tag="TV186_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1532297.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            18348..19610
                     /gene="purD"
                     /locus_tag="TV186_000892"
     CDS             18348..19610
                     /gene="purD"
                     /locus_tag="TV186_000892"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL1532298.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            19839..20327
                     /gene="purE"
                     /locus_tag="TV186_000893"
     CDS             19839..20327
                     /gene="purE"
                     /locus_tag="TV186_000893"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL1532299.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            20314..21387
                     /gene="purK"
                     /locus_tag="TV186_000894"
     CDS             20314..21387
                     /gene="purK"
                     /locus_tag="TV186_000894"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL1532300.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            21402..21626
                     /locus_tag="TV186_000895"
     CDS             21402..21626
                     /locus_tag="TV186_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL1532301.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            22223..23515
                     /gene="purB"
                     /locus_tag="TV186_000896"
     CDS             22223..23515
                     /gene="purB"
                     /locus_tag="TV186_000896"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL1532302.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
     gene            23813..24726
                     /locus_tag="TV186_000897"
                     /pseudo
     CDS             23813..24726
                     /locus_tag="TV186_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            24809..24907
                     /locus_tag="TV186_000898"
     CDS             24809..24907
                     /locus_tag="TV186_000898"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL1532303.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
     gene            24941..25948
                     /gene="ruvB"
                     /locus_tag="TV186_000899"
     CDS             24941..25948
                     /gene="ruvB"
                     /locus_tag="TV186_000899"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL1532304.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            26189..26647
                     /locus_tag="TV186_000900"
     CDS             26189..26647
                     /locus_tag="TV186_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL1532305.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            26653..27054
                     /locus_tag="TV186_000901"
     CDS             26653..27054
                     /locus_tag="TV186_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532306.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            27051..28832
                     /locus_tag="TV186_000902"
     CDS             27051..28832
                     /locus_tag="TV186_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL1532307.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            29252..31894
                     /gene="adhE"
                     /locus_tag="TV186_000903"
                     /gene_synonym="adhC"
     CDS             29252..31894
                     /gene="adhE"
                     /locus_tag="TV186_000903"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL1532308.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            32389..33441
                     /locus_tag="TV186_000904"
     CDS             32389..33441
                     /locus_tag="TV186_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL1532309.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            33644..34660
                     /gene="adhP"
                     /locus_tag="TV186_000905"
     CDS             33644..34660
                     /gene="adhP"
                     /locus_tag="TV186_000905"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL1532310.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            35376..>36414
                     /locus_tag="TV186_000906"
     CDS             35376..>36414
                     /locus_tag="TV186_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532311.1"
                     /translation="MKEIVRSHRLLYVIVAFFSVISAFLMTLFSIQLGKILDSISNSS
                     SELLFQIVVCVCTIMAWFIMIWSYSYFKSYYVKKVILDLKERLFIGYLLREFNEIDTC
                     DRYNSDFLNNVTKNIDIIQENLLVPRVAVIVDLASMVTSVVAIVLIEWRLALVFLLLS
                     IVTVFLSQIPGKLMSKATRYYSEKSNHYLAEMTSFIEGFEQIKLLNIQKWIQKIEQNT
                     TLEFEDSRQKYQYRKDLASNTGMFLSFFSQVACMVAGIFFVRNNLLTVGLLVASIQLL
                     NGVFGPLQSFLYNKNLIKSTGTILTSIQEVLDKTNFVNGYIENKTFYEGDISSISINN
                     LTYQVENRKIFT"
BASE COUNT        10463 a         6456 c         8497 g        10998 t
ORIGIN      
        1 ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaacag cgtgcgtggg ttcgaatccc
       61 acatcctcct ttaaagatta tcgcgggatg gagcagttag gtagctcgtc gggctcataa
      121 cccgaaggtc gtaggttcaa atcctgctcc cgcaattata taaaagatat atgctggttg
      181 gctcggtagc tcagttggta gagcaatgga ttgaagctcc atgtgtcggc ggttcgattc
      241 cgtctcgcgc cattttagcg ggtgtagttt agtggtaaaa ctacagcctt ccaagctgtt
      301 gtcgcgagtt cgattctcgt cacccgcttt atagttttcc caagctatag tgtgcttggg
      361 cgcgtagctc aggtggttag agcgcacgcc tgataagcgt gaggtcggtg gttcgagtcc
      421 actcgtgccc atcattattt ggagaattac tcaagaggct gaagaggacg gtttgctaaa
      481 tcgttaggtc gggtaactgg cgcaagggtt cgaatccctt attctccgta ttgtaaaggt
      541 gattatcata ctgataatcg tttttttatt tttagaggtg attttattga aaaagcttaa
      601 cctatctcgt ctcttttttt ggttaacatc attagcttta ctggctttga ccttggttct
      661 tctttttaga gtagctattt ctccatattt atcaatgatt atccgaaatc ccgttacaaa
      721 aattgatgct ataatgtcta agccttttgc tgttataaag gagggtgcaa aggaattaga
      781 tagcttgatg tctgcttttt ctgaaaataa gcatttaaaa aaggaactta ggtcctataa
      841 attggatcag ttacaggttg acaagctaaa atctgaaaat cgagagctca aggaactgtt
      901 agggttggat tatggtactg ataatcaatt tgctgccaga atgatatcaa gaaatcctta
      961 tagctggaat aaatcgctgg tcattgatag cggcaaaagg gaaattaagg agaagtcttt
     1021 ggttacttca gagcttggac ttattggtcg tgttacagct gttagccagt catctgctca
     1081 tgttgaattg ttaacatctg ggaagaatat tgagttgccg attaaaattg tagataagga
     1141 taaggtgatt tatggcaatt taaaggcatt taaatcagaa agtaaaacaa tggttgccag
     1201 cgaatttaat tctaatgact caatatcatt agatgctaag gtttatacaa gtggattaga
     1261 tggtgagact gtggcagata ttcctgttgg aaaggttacg ggctttaaaa atgctgctga
     1321 taagctaaag cgtcgtattt ttataaaatt gtatgctgat actgataatc ttgactatgt
     1381 tcttgttgtt ggaaaagagt gaatatgaaa aaatcttcag agctattagt ccttttgcct
     1441 tttcttttat tttttgttga tgcacacgtg tcagacctga tcagctcaat gttacctgag
     1501 ggttactcgg tagtatcaca cctcttttta ctgtttttcc tgatccttat ggtagcgttt
     1561 agatctaagg gagttatttg tttcttctct cttcttttag gattattgtt tgattattat
     1621 tattttgatc atatagggat tttgtctctt gccttgcctt ttggaacaat gatcgttcta
     1681 gggctattaa ggttcttttc tggttccatt agtcagctac aatttttcct tttctttact
     1741 ctttatatgt ttcttgtaga tgtatcaagc tttattttgg caaacagcta tcagttaact
     1801 gatatgactt ttccttatgt aatgacgttt cagcttgctc cgactttaat cgtcaatctc
     1861 cttattttgt tttgctttag aaaattaata ttaagtcaat tttattgatt attacataca
     1921 actgtaacag atgcgtaaca ttaaacgctt gattttttga tagaatataa tgtgtcttat
     1981 cgaaaaggag taattttttt agtatgaaaa aaagaattct atcagcggtt cttgtaagcg
     2041 gtgtgaccct tggaacagca actacagtgg gagcggatga tttagattcc aaaatagcgt
     2101 tgcaaaattc agttatttct aatttaaata aagaacaaaa agctgcgcag gatagaatga
     2161 agactttgca aagtcaggtt agctcattac aatctgaaca agaaaggtta gtcgctaaaa
     2221 atggtgagct tgaagcgcga tctgctcagt ttgagcagga gattcaagtg cttgccagtc
     2281 aaattattgc tcgtaatgaa aagttaaaag gacaggctcg tagtgctcaa aagggaaata
     2341 cgttaggtta cctcaatgca cttttgaatt ctaagtcaat ttctgacgtt attactcgtt
     2401 tggttgctat taatagagct gtgtcagcca atgcacagat gttggaaaag caaaaggctg
     2461 ataagctttc tcttgaagaa aagcaacagg aaaatcaaga agcgattaat acaattgctt
     2521 caaatattac agcaattgaa tcaaaccaag tagctttaaa gactcaacaa gcagatttag
     2581 aggttgccaa ggtagatttg gcgcttcaat tagcaactgc tgaggacgag aaggctagct
     2641 tgattacccg taaagaggct gcagagcagg cagcagctca agccaaggct caggcagagc
     2701 aggaagcagc agccagagca gcacaggctc aagctcaagc acagtctgta gcggcagctc
     2761 aagcagcagt gactcaagcc gtaccaacac cagctccagc gcaggcacag cctgttgtgg
     2821 cgccagcagc tatggtttca acaccagcgg tgtcgtatgc ctatgatcct tctaatccgt
     2881 accctgtcgg ccaatgtact tggggagtta aggctttagc tccttgggtt ggcaattatt
     2941 ggggaaatgg tggtcaatgg gcatcaagtg cagcggcagc aggtttccgt gtaggtgcaa
     3001 caccaatggt tggctctgtt gttgtatgga atgatggtgg ctatggtcac gttgcctacg
     3061 taacaggtgt tcagggtgga cagattcaag ttatggaagc caactatgct ggaaatcaat
     3121 ctattggcaa ttatcgtggt tggtttagcc caggtgctgt atcgtatatt tatccaaatt
     3181 agaaaataag taaaggtaag aatcaggatt cttacctttt tatttccatt gaaaaattga
     3241 ttgaaaaggg ttaaaatggt ataggatcaa aactttggag gaaaaaatgt cttattctga
     3301 tttaaagctg tttgcattat cgtcaaacaa ggaattagca gaaaaagttg ctgctgcgat
     3361 gggaattcaa cttgggaagt ctacggttcg ccagttttca gatggtgaga ttcaggtcaa
     3421 tattgaggaa tcaatacgtg gacaccatgt ttttattttg cagtcaacaa gctcgcctgt
     3481 taatgataac ctaatggaaa ttttaattat ggttgatgct ttaaagcgtg ccagtgctga
     3541 gaaaatttct gtggtaatgc cttattatgg ctatgctcgt caggatcgta aggctcgttc
     3601 gcgtgagcct attacctcta aattagtcgc taatatgcta gaggtggcag gtgttgatcg
     3661 tttattgact gttgatttac atgctgcgca gattcaaggc ttctttgata ttcctgttga
     3721 tcatctcatg ggagcacctt taattgctga ttattttgat cgtcatggtc tagtaggtga
     3781 tgacgttgtt gttgttagcc cagatcatgg tggtgtgacg cgtgctcgta agctggcaca
     3841 attcctccaa acgccaattg ctattattga taagcgtcgt agtgttgata aaatgaatac
     3901 cagtgaggtg atgaatatca ttggtagtgt tgaaggtaaa aaatgtattc tgattgatga
     3961 tatgattgat actgctggta ccatctgtca tgccgctgat gcgcttgctg aagcaggagc
     4021 aacagcagtt tacgcatcat gtactcaccc agtgctgtca ggaccagctc ttgataatat
     4081 tcaaaaatca gcgattgaaa aattgattgt tttggatacg atctatttac cagaagaaag
     4141 actgattgat aagattgaac aaatctctat tgcagatttg attgcggaag ctatcattcg
     4201 tatccatgaa aaacgtccat tgtcacccct atttgaatta gggaaatgat aaggttagcc
     4261 tgaggtagta agccttaggc ttttttatgt tttaaaaggc tatttgatta ccaaagcagt
     4321 gtttgattta acgccataga taggcttcac tgtcttatgg taggtgttga gctattatag
     4381 caaaaagtca tgtgtaggtg ctgtgtttaa acagctagcc tatgattcat atagttatgg
     4441 ctagtgactg ttgagcttct tattctcaga gttgttacga gccttaagta cagtgttagt
     4501 catgcaattt tcctggattt tgggtataat atagctgtat ttaaggtgtt ttaaaggtct
     4561 agtaagaaag gcattattac tagctgagaa gcttggttat ggagatatat gcgtattcag
     4621 aggtcacttg gtattgtctt gtacaataaa aactatcgtg aagatgataa gctcgtaaaa
     4681 atatttacag aagcggcggg caagcgtatg tttttcgtga aacatattgg tcgttctaaa
     4741 ctagctcctg tggtccagcc tttaacggct gctgattttc tattgaaaat caatgattcg
     4801 agcctttctt atatagagga ttataatcag gtggaggctt atcggcacat caatgaagat
     4861 ttttttaggc tatcctatgc tagttatgtc ttggctctgg ctgatgcggc tattccagat
     4921 aatgagcctg atcctcagtt gtttgctttt ttgaaaaaga ctcttgatct gatggaagaa
     4981 gggctagatt atgacatttt aacgaatatc tttgaagtcc agattttgga tcgttttggg
     5041 gtgagaatga attttcatga ttgtgttttt tgtcacagaa ccaatctgcc ttttgatttt
     5101 tctcataagt attcaggtgt cctttgtccg cagcattacc atgaggatga gaggcgatat
     5161 ggcttggatc ccaatgtgat ttatttgctt aatcgttttc aaacgcttaa tattgatgag
     5221 ctaaagacta tttctgtgaa tactggtatg aaaaaaaagc ttcgtctttt tattgatgcc
     5281 ttgtatgagg attatgtcgg tattcgtcta aaaagtaagg tttttattga tgatttggct
     5341 aagtggggag atattatgaa aaacaagcag ggcttgtgag ctattcaggt gtggatttgt
     5401 ccttttatgg gaattgtctg gggaatatgc tataatagtt acgttattct ctaggatatt
     5461 tttcgttaag aaaaatagga ttaaaggagc aaaaatgaag aaaattgcaa tagacgctat
     5521 gggtggtgat tatgccccta aagctattgt tgagggtgtt aatcaggcga tagaatcctt
     5581 ttcagatatt gaaattcagc tttatggcga tcaatcaagg attgagtctt acctagttaa
     5641 atcagatcgt gtgtccattg ttcatacaga tgaaaaaatt aattctgatg atgagccagc
     5701 aaaggctatt cgtcgtaaga agaatgcttc tatggtttta gctgcaaggg cagttaagga
     5761 tggtcgggct gatgcagttc tttcggcagg taatacaggc gccttgttag ctgctggttt
     5821 gtttattatt ggtcgtatca agggagtgga tcgtcctggt ttgctgtcaa ctctgccaac
     5881 ggttgatggt tcaggctttg acatgttaga tttgggtgcc aatgctgaaa acacagcaga
     5941 gcatttacac caatatgcta ttttaggctc tttttatgca aaacatgtgc gtggtattgc
     6001 caagcctcgg attggcttgc ttaataatgg tactgaggca actaagggtg attctcttcg
     6061 caaggaggtc tataattttt tagcttcaga cagcagccta cagtttattg ggaatgttga
     6121 ggcaagagat ttgatgtctg gcgtggcaga tgttgtggta gcagatggct ttacaggaaa
     6181 tgctgttttg aagtcgattg aaggcactgc tatgagtatt atgggacaat tgaaatcagc
     6241 tatagcagta ggtggtgtta aggcaaagtt tggagctctt ttattgaaga gtagccttta
     6301 tgacttaaag gatactttag attattccag tgcgggtggg gctgtattgt ttggtcttaa
     6361 agcacctctt gtgaaatcac atggttctag tgatgccaag gctatttttc ataccattaa
     6421 gcaggttcgt acgatgctag aaacagatgt agttggccaa ttagttgagg agttttctaa
     6481 ggagagtgat gtaaatgact gaggaagtta ttttagagaa aatcatcgca ttaatcaaga
     6541 agcaaagaag tcgtatagac tttgacatta cagaaaaaac agcactaaag gatgatttag
     6601 gagtagattc gattgaactg gtagagtttg ttattaatat cgaagatgaa tttggtattg
     6661 atattcctga tgaagatgtt gatggcatgg tatctatggg agatatgcta aattatttgg
     6721 tcaagcgttt aaaccaaagc taaatagttt taaaagagca ccagctcttt ttttgtttcc
     6781 gaaaaaacga acattataag tttattttat attaaatgta aataaatgtt gaatatttag
     6841 tatgtttgtg gtattgttta gatattaaat gcaaagaaag gcgaacaaat aagtgtctaa
     6901 tcaactcatt tattcaggta aggcaaagga tatctatgaa acagccgatg acgggattgt
     6961 cttaatctcc tacaaggatc aggtcactat gctaaatgga gcacataagg aaatgattga
     7021 aggaaaaggg agccttaata atcagatttc tgccttaatc tttgataggc taaatagggt
     7081 tggcgtatca actcatttta ttaagcaatt atccgagaca gaacagttaa ataaaagggt
     7141 tgcgattatt cctttggagg ttgttttacg aaacgtggcc gctggctcat tttcaaagcg
     7201 ctttggtgtt aaagaaggtc aggctttgga cgagccaatt attgagcttt attacaagaa
     7261 tgacgcttta gatgatcctt tcattaatga tgagcatgtc agctttttaa agcttgcgac
     7321 tgatgagcag atagcctaca tcaaacaaga gacgcatcgt attaatgctt atttgaagga
     7381 gtggtttgct agtgttgggt tgacactggt tgattttaag ctagaatttg gctttgataa
     7441 ggaggggatg cttatccttg ctgatgagtt ttctccggat aattgccgct tgtgggataa
     7501 tgcgggccgt cacatggata aggacgtttt tcgtcgtcag cttggcagtt tgacgcaagc
     7561 ctatgagact gttttagaaa ggctaagagc attggatcaa taaagaccag cttatttgtt
     7621 gtcagttaag aaagggagct cttttttgtc cgtcatgtaa gaaaataaat cagttcagac
     7681 tatttgagct gctgtctaag aaaggctgtc tgctattgga gaaaagagtc aggctagttc
     7741 ttattttggg ctggtttctg attggacttg gtatattaac tatgaataaa cgtatttttg
     7801 ttgaaaagaa ggctgatttt cagattaagg cacaggtcct gttaaaggaa ttgaaacatc
     7861 agctgcagtt aaagacactg gttgatttgc gtattgtgca ggtttatgat gtgtttcatt
     7921 tggatcagga gctgctttta acagctataa agcatgtttt ctctgagcag gtcactgatc
     7981 aggtattgtc agaagaagct ttacaagcag atttaaaaag gtatgccttt tttgcgattg
     8041 aagctctgcc tggacagttt gatcagcgtg cggcaagctc tcaggaagcc ttattgttgt
     8101 taggagcctc aactgatgtg actgttttga cctcacagct ttatttggtc aatcaagaca
     8161 ttgctgctga agaattagaa gccttaaagc agtacttgtt aaatccagtg gattctaggt
     8221 ttaaggacat attagccggt cttgatgatc aggatttttc agtagcagat aaagtgattc
     8281 caacgcttga tgtttttaat gattatacag cggaaaatct tgctcgttac aggtctgagc
     8341 agggcctagc aatggaagtg gaggatctgc tgtttattca ggattatttc aagacaaagg
     8401 ggcgagtgcc aacagagact gaactaaggg ttttggatac gtattggtct gatcattgtc
     8461 gtcacacaac ctttgaaaca gagctaaaaa cgcttgattt ttcagcttct cattttgaaa
     8521 agcagctcca agctacctat gagacctacc ttgctatgcg tgatgagcta ggtcgatctg
     8581 aaaggcctca aacgcttatg gatatggcta ccatttttgg acgttatgaa agagctaatg
     8641 gtcgtttaga ggatttggag gtttcagatg aaatcaatgc ttactcagtg gaaattgagg
     8701 tagatgttga tggtgtcaag gagccttggc tgctcatgtt taaaaatgaa acacataatc
     8761 acccaacgga aattgaaccc tttgggggtg ctgcaacctg tattggtgga gctattcgtg
     8821 atcctctgtc aggccgttcc tatgtttatc aagccatgcg gctttctggt gcaggggaca
     8881 ttacaagccc gctgtcagag actcgtaagg gcaaattacc acagcaggtt atttcgaggc
     8941 aagcagcaca tggttactcg tcatatggca atcaaattgg gctagcgact acttatgttc
     9001 gtgagtattt tcacccaggc tttgttgcca aacgtatgga gcttggtgcg gtagttggtg
     9061 ctgcacccaa ggaaaatgtg gttcgtgaaa agccaaggac aggtgacgtg gtggttttgc
     9121 ttggtgggaa aacaggacgt gatggtattg gtggtgcgac aggatcatct aaggttcaga
     9181 cagttgagtc tgtagaaaca gctggtgcag aggtccaaaa aggaaatgcc attgaggagc
     9241 gtaaaatcca acgtcttttt cgtcgtggcg atgtgacacg cctcatcaag aagtcaaatg
     9301 attttggtgc tggtggtgtt tgtgtagcca ttggcgagct tgctgctggt cttaacatta
     9361 acttagataa gattccttta aaatatgctg ggctaaatgg aacagaaatt gccatttcag
     9421 aatcccaaga gcgtatggct gtcgtgattt gtccaaagga tttagaggcc tttatgagcg
     9481 cctgccataa ggaaaatatc catgctgctg ttgtggcagc tgtgacagaa aaaccgaatc
     9541 ttgttatgac ctggaatggg cagacgattg ttgatattga acgctcattt ttagagacaa
     9601 atggtgtgcg cgtgtctgtt gctgctaagg ttgttgacag tggtgcgcca ataccagaag
     9661 ctcgtcaaac tactgctgag acacttgaag cagataccat tgctgtctta tcagacctga
     9721 accatgctag tcaaaagggt ttgcaaaccc tgtttgatag ctcagtgggt cgctctacag
     9781 taatacatcc gcttggtggg cgctatcaaa tgacacctgt tgaaggctct gttcagaaat
     9841 taccagttca acatggagtg acaaagacag tctctgttat cgctcaaggc tatcaccctt
     9901 atatagccga atggtcacct tatcatggtg ctgcttatgc tgtaattgag gcaactgctc
     9961 gtctggtcgc aacgggtagc cattggcata aggcacgctt ttcatatcag gaatatttcc
    10021 aaagaatgga taagcaggca gagcgctttg gtcaaccggt ggcagccttg cttggagcaa
    10081 ttgaagcaca ggtgcagctt ggcttgcctt ctattggagg taaggattca atgtctggta
    10141 gctttgagga attgacagtg ccgccgacct tggttgcctt tggtgtgacg actgctcatg
    10201 tagatcatat cctttcacca gaatttaaag ctgctggcga gaatatttac tatattccag
    10261 gacaggctat ttcggaagtg attgattttg agttgataaa atctaatttt atgacttttg
    10321 aggctattca gaaaaagcat aatattagct cagcttcggc tgttaaatat ggtggtgttg
    10381 ttgaagcact ggctcttgct gcctttggta atcggttagg ggcttgtgtg acattaccag
    10441 agcttgacag gagcttaaca gctcagcttg gtggctttat ctttacatca aaagaggaaa
    10501 tcacaggtgt tatcaagctt ggtcaaacta ccagtgactt tacattggtt gtcaatgatg
    10561 tcaagctatc tggagctcgt ctcttaaagg cttttgaagg gagcctggag caggtttacc
    10621 cgacggtatt tcagcaggca ggtgaattga agcctgttcc tgtagtgaca acagcacttg
    10681 ctgctcagtt taaggaaaaa atagctcagc cagttgtcta tattccagtt tttccaggaa
    10741 ctaactcaga atatgattcg gctaaggcct ttgaaagaga gggtgcaagg gtgaacttgg
    10801 tgccttttgt taccttgaat gaggcagcta ttgacgcttc agttgacacg atggttgacc
    10861 atattcatca agctcatatt atcttccttg caggtggttt ttcagcggca gatgagccag
    10921 atggttcagc taaatttatt gttaatatcc tgctgaatga gaaggttcga atggcgattg
    10981 atgcctttat tgaaaagggt ggtctgatta tcggtatttg taatggcttt caagctctgg
    11041 tcaaatcagg gctgctgcca tatggacgtt ttgaggcggt acatgaggct agtccaactc
    11101 tgttttataa tgatgccaat cagcatgtgg ctaaaatggt agaaacgcgt attgccaata
    11161 ccaattctcc ttggctggca ggtgtcaggg tgggggatat tcatgctgtt gcagtgtcac
    11221 atggagaggg caagcttgtg gtaacagaaa gagaattagc agagctttgt aaaaatggtc
    11281 agatttttag ccagtatgtt gaccttgatg gtaatccaag catggatagc aggtataatc
    11341 caaatggctc tgtcaacgct attgaaggtc ttaccagcaa aaatggtcag attatcggta
    11401 agatgggaca ttcagagcgc tttgaagagg gacttttcca aaatattccg ggtaataagg
    11461 atcaatggtt attccgaagt gcggtgcatt attttagagg agaccatgtg ggtattgact
    11521 gaactgggat atagccttgt aatagctaag atagctgcta ttattgctca gcctagctgt
    11581 tagttctagc ttagttaatg acacaatcat aattaaaagg gcattagccc agaggtaaag
    11641 atgacatatg acgtaaaatc tcttaatgag gaatgtggtg tttttgggat ttggggacac
    11701 ccacatgccg ctcaagtgac ttattttggg cttcatagcc tacagcaccg cggccaagag
    11761 ggagcaggta ttatttcaaa tgataatggg gagcttcatc agcatcgtga tgtaggtctc
    11821 ttgtcagagg tgtttaagga ttcatctgat ctggacaagc taaagggaca tgctgccatt
    11881 ggtcatgtgc ggtatgcgac tgctgggacg gcttccatta ataatattca gcccttttta
    11941 tatcgtttta cagacgctca atttggcttg tgccacaatg gtaatttgac caatgctatg
    12001 tcattgaaaa aagcgttaga gagtgaggga gctattttta atgcctcttc tgatacagaa
    12061 attctaatgc atttgattcg tcgtagtcat cacccagaat ttttaggaaa ggtaaaagag
    12121 gcactcaaca ctgttaaagg gggctttgct tacctgctga tgacagagaa ccagctgata
    12181 gcagcgcttg atccaaacgg ctttaggccg ttgtctatag gccgtatgaa aaatggggct
    12241 tgggtcgtct caagtgagac ctgtgccttt gaagtggttg gtgctgagtg ggttcgcgat
    12301 gtgatgccag gtgaggtcat tatcattgat gatcagggga tcacttatga ctgctatacg
    12361 actactacgc agctggctat ctgctctatg gaatatattt actttgcgcg tcctgattca
    12421 accattgctg gagtcaatgt tcacaccgct cgcaagcgaa tgggaaagag actggctcag
    12481 gaatttcagc atgaggctga tattgtggtt ggtgtgccaa attcctcatt atcagcagcg
    12541 atgggctttg cagaagcatc aggcctgcca aatgaaatgg gattggtcaa gaatcaatat
    12601 acccaacgaa cctttatcca accaactcag gagcttcgtg agcagggagt tcgaatgaaa
    12661 ctttcagctg tttcaggtgt tgtcaagggc aaaagggttg tgatggtaga tgattctatt
    12721 gtcagaggga caacctcacg acgcattgtt aatttgctgc gtgaagcagg agctacagag
    12781 gttcatgtag caattggtag ccctgagctc aaataccctt gcttttatgg gattgatatt
    12841 cagacaagac gggagctgat ttcagctaat catactgctg ctgaggtctg tgatattatc
    12901 ggtgctgata gcctgactta tttgtcactt gatgggctta tcgaggctat tggacttgat
    12961 acaaaagcac caaatggtgg gctttgtgtg gcttattttg acggtcagta tccaacgccg
    13021 ctttatgatt atgaggaggc ttatctcaag agcttagaag aaaaggtaag ctttcacatt
    13081 gatcaggtga cgaagtagcg ctttatggct aacatagaat aaatgatcta ggcagctaaa
    13141 ataaggagga gaaaatgtct aaaaatgctt atgctcaatc aggtgtcgat gttgaagcag
    13201 gctatgagct tgttgagcga ataaaaaagc atgccgagcg tagcaaacga ttgggtgtta
    13261 tgggtggtct aggaggcttt ggtggtctgt ttgacctgtc aaagactggt gttaaggagc
    13321 ctgttttggt ttcagggaca gatggcgtcg gaacaaagct aatgcttgca atccagtacg
    13381 ataagcatga cacgattggg caggattgtg tggcaatgtg tgtcaatgat attattgcag
    13441 caggtgccga acccctgtat tttcttgatt accttgcagc aggaaaaaat gagcctgcca
    13501 aattagagca ggtgattgca ggtattgctg agggctgtgt tcaagcaggt gctgctctta
    13561 tcggtggaga aactgctgag atgcctggta tgtatggtca agatgactat gatcttgccg
    13621 gttttgcggt tggtattgct gagaaatctc agctgattga tggttcaaga gtagctgagg
    13681 gagatcatct cctaggtttg gcatcaagtg gagttcattc aaatggttat tccttggttc
    13741 gtcgtatttt tgccggttat actggtgagg agctgcttcc agagcttgat ggaaaaaagc
    13801 ttaaggaggt acttcttgag ccaactcgta tttatgtcaa ggctgtgtta ccactcatta
    13861 aaagcggctt agtggcagga atcgctcata ttacgggtgg cggctttatt gaaaacctac
    13921 ctcgtatgtt ttccaaagaa ctagccgctg aaattgaaga agccagctta cctgtgctgc
    13981 ccatttttaa agtccttgag acatatggta agatcaatca tgaagaaatg tttgagattt
    14041 ttaatatggg tattggcatg gtgcttgctg tcaagcctga gcacgttgag caggtgaagg
    14101 cctgtcttga tgagcctgtg tatgacattg gtcgcgttgt gaccagaaca gttgctagtg
    14161 tggtgatgaa gccatgacaa gaattgccgt ttttgcttct ggtaatggct ccaattttca
    14221 aacgattgca gaacagtttc cggttgcctt tgttttttct gatcattgcg atgctcatgt
    14281 tttaagtaga gcctgtgctt tgggtgttct gtcctacagc tttgaactaa aggactttga
    14341 gaataagcaa gcctatgagc agactcttgt ggcattgctg cagcggcatc agattgatct
    14401 catcgtcctt gccggctata tgaaaattgt gagtacaacc ttacttgatg cttacgaagg
    14461 aaaaatcatc aacattcacc cagcttattt gccagaattt ccaggagcac atggtatttt
    14521 agatgcttgg caagcaggtg ttagtcagtc aggagtgact gttcattggg ttgatagtgg
    14581 tattgataca ggaaaaatca tcaaacaggt acgagtacca cgtttgagtg atgatactct
    14641 tgaaagcttt gaagccagaa ttcatgaagc agaataccaa ttgtatccag aggtactgga
    14701 tagtcttgga gtagagcggc ttaaccgctg attgtgtaag attaataact attttcccta
    14761 ttgtggcatt tcgtttatca tagcagctgc gctaatggtg gctaacaaag gctagaagac
    14821 ttgtttgatg atggcactgc tattgaggaa aatagacttt tctaaggaga acttaaaatg
    14881 actaaacgcg ccttaattag cgtatcagat aaaagaggga ttgtggacct tgctagggag
    14941 cttaagcatc ttggctggga tattatatca acaggaggaa caaggcttgc tcttgaagag
    15001 gctggtgtag ttactgttgc tattgacgat gtgacaggct ttcctgaaat gatggacgga
    15061 cgggtaaaaa cgctgcaccc tctcattcat ggtggcttac ttgctcgtcg tgacattgag
    15121 caccacttac aggcagcaaa gcaaaacagg attgaattaa tagaccttgt tgttgttaac
    15181 ctttatccct tcaaagaaac catttgccgt ccagatgtca cttatgatgt cgctgttgat
    15241 atggttgata ttggtggtcc ttcactgctg cgttcagcgg ctaaaaatca tgctagtgtt
    15301 acggtagtgg ttgatccgac agattatccg ctcgttttag gagagttggc tagcactggc
    15361 agtacaagtt accaaacccg tcaaagctta gcagctaaag cttttcgcca tactgcagcc
    15421 tatgatgcag tgattgcaga ttattttaca agacaagcag gtgagacaaa gcctgaaaag
    15481 ctcacgctta cctatgattt gaagcaaagc atgcgttacg gtgaaaatcc tcaacaggct
    15541 gcagattttt accaaagagc gctcccaaca acctattcaa ttgcttcagc caagcagcta
    15601 aatggaaaag agctatcatt caacaatatt cgtgatgcag atgctgcgat tcgtattatt
    15661 cgtgatttta aggagcgtcc aaccgttgta gcactcaagc atatgaatcc atgtggtatt
    15721 ggtcaggcag atgatattga gacagcttgg gattttgctt atgcagctga tccggtgtct
    15781 atctttggtg gtattgttgt cctaaatcgt gaggtggatc tagcgacagc ggagaagctt
    15841 catgctattt ttcttgaatt gatcattgca ccaggctatt ccaaagaagc gctagctgtt
    15901 ctcacccata aaaagaagca cttgcgaatt cttgaattgc catttgctgc tcaggaggct
    15961 agtgaaatag aagcagaata tacaggagtt cttggtggtc tactagtgca aaatcaagat
    16021 gttgtcacag agtctccagc ggattggata gtggtgacaa agcgtcagcc aaatgaacag
    16081 gaaatggctg ctctagcatt tgcttggaaa accatcaaat atgtcaagtc taatgcgatt
    16141 gtcattgcta atgatcatat gactttgggc gttggtccag ggcaaacaaa ccgaatagcc
    16201 tctattcgta ttgctattgc gcaagcaacg gggcagcttg agggagcagt tcttgctagc
    16261 gatgccttct tcccatttgc agacagcatt gaagaaattg ctgccgctgg tatcaaggct
    16321 attatccagc ctggaggctc tattcgtgat tcagaatcta ttgcagctgc caatcagcat
    16381 ggtataacca tgattttcac aggtgtgagg cattttagac attaataaag taaaaagaga
    16441 ctggagccaa aagagttgca ctttagaaat tcttggttaa tatactttat tacctagttg
    16501 gattcattaa aaagcgaaca agtctagttt tcataatctc agaaaactag acttgtttgc
    16561 ttgttttatt tggtggtcat actattgttt cagcctcttt ttactatgac taatacaaga
    16621 atttatgaag gaacaaggct ttattttttg ttgtggtaac agtgaccaga tccgttatca
    16681 atcagtattt gagtattttg agctctagat gcatcactta gataggatat tgcaaaggat
    16741 acagctgctg catgtattag gaaagcatta tcataaaagg ctttttcgtt agcctaaagg
    16801 ttttagacct tctttgcctt atctattgtt aaccatgttc cacgtgaacc catttgcacg
    16861 taaatcccct tgctaggctg atcaaccttt agaaccttat aggttcctga aacgacaaaa
    16921 taatcaccca cctgcaaaat ctgatttcca gcaatacgtc ctttatggtc cgtttcgtgg
    16981 agtggagctg agtctatcca gtttaaggag gttggctctc caccggctaa ttcactgctt
    17041 gcaatcatgt tctgagcgac ctgatcgacc cgaaaaacac caggaaaggc tacagtatct
    17101 ccaaccttga taggagtggt cgccacaggc tttggtttat ctatagaggc ttgactatgt
    17161 tgctgaggct gaaccggcaa tttgtgaatt ggaatgtagc gatgatttcc tgaatgaccg
    17221 atatagctga gccattcata gccatcagcg acaagggttt gatcatagtg cactaactgt
    17281 ccagtatgat agtaagctaa atcaggactt gctaatgtag cttcagcctt tataggactt
    17341 tggcttgaaa aataataggt accactttta gctagacgag ttgatcctgc ttgagaagca
    17401 tgtaacattt gtgtgtggct ggtagagttg tgatccagat ccttgaagtg aatgtaacca
    17461 cttacctgat gcttatgaat ctgtcgttta tgatactttt caggtccctg tccggcatta
    17521 tagttgtatt cctcaataat aacagtgtca ccattgacct ctgctaccca ggcgacgtgt
    17581 ccatataggg catgtgactg gttaaagccc ttatcccacc aagcaacagc accaactcta
    17641 ggtgtatgat caacatgata gccttggtgt ttagctatac gtccccagct ttcaacatta
    17701 ccatagcctc taggcaggct gaatccattt gaggaatgca gtcggaatgc tacaaaagaa
    17761 gtgcattgac gtaagtacat gttccaagga tcagctccga agccctgttt ccacttactt
    17821 ggatagttat cccctaaaac agcagcgtgt acgatacctg actgaccttg tgaaatcgtt
    17881 gttgtggcag aggatattgc accattacca cctaaaagga ttgctcctga agctaacaat
    17941 tgatagactt ttttcattaa ttacctcctg taacttacta ttcgcaagaa agaggacaaa
    18001 aatgtccttg atttaaaaaa atgtaaggaa aaatatttta gcctcaaaat actgttggtg
    18061 ctccctagct tccaagagcc aataggcaag cccatctcca gcttgcctgc tccctgtagc
    18121 taaaagcaat ttatagtaac actagcacct catctgaaga ggcaggctgt ggtaattaat
    18181 gccaataatc tgtaaaaaga gacagcaggt atggttatat gagctatgat ggttatattc
    18241 tataaagctt attttttagc ttcgggcttt ctttggtgat tagttattta tataaacgaa
    18301 caattatgct aaaatatgtt tataaaattc gtgttatgag gtgtgtgatg aagcttttag
    18361 ttatcggttc aggtggtcgt gaacatgcga ttgctaagaa attgttagag tcaaaaggcg
    18421 ttgaacaggt ttttgtggca cctggcaatg atggcatgac ccttgatggc atagaacggg
    18481 tagatattga tatttccgaa cattctgctt tgattgcttt tgcaaagacc aatcatatag
    18541 cctggacctt tgtgggacca gatgacgcat tagcggctgg tatcgttgat gagtttaacc
    18601 agtctggctt gaaagccttt gggccctctc gtttagcagc ggagctggag tggtcaaagg
    18661 actttgctaa gcaaatcatg gtcaaatacg gtattccaac agcagcctat ggcacatttt
    18721 ctgattttgc aaaagccaag gcctacatcg aggaaaaggg cgcgccaatt gtggttaaag
    18781 cagatggttt ggcgctagga aagggtgttg tcgtagcaga gactgtagag caggcagttg
    18841 aggcggcgcg tgacatgctc ttggataata aatttggtga ttcaggtgcg cgcgtggtga
    18901 ttgaggaatt tttagctggt gaagagttct ctctctttgc ctttgtgaat ggcgatcagt
    18961 tttacctcat gccgacagcg caggaccaca agcgggctct tgatggtgac aaggggccaa
    19021 atacaggtgg tatgggggct tatgcaccag tgcctcatct ttctcaaagt gtggtggata
    19081 cagcagttga gaccattgtc aagcctgttc taaaagggat gatgacagag gggcgtccct
    19141 atcttggaat cctttactgt ggcttgattt tgacagaaga tggaccaaaa gtgattgaat
    19201 tcaatgctcg ctttggtgat cctgagactc aggttatcct tcctcgcctg acctctgatt
    19261 ttgcacagaa cattaccgat atattagagg gcaacacagc taatatcaca tggtcagacg
    19321 agggagtgac gctcggcgtt gtccttgctt caaacggtta tccgcttgct tacaagaaag
    19381 gtgtgcttct gccagcaaag accactggcg acatcattac ctactacgca ggggttaagc
    19441 ttgcggaaaa tggcaaagca ctgctgtcaa atggtggacg tgtctatatg ctggtcacca
    19501 cagcagttac cgtcccagct gcgcaagaaa aaatctatac cgaacttgct cagcaaaata
    19561 ccgaaggatt attctaccga aacgatattg gaagaaaagc agtaaaataa attagcgcta
    19621 gctcaagcta ccgaaggtcg ctatgatgac aatgacttat tatcggtgag caaaagcgag
    19681 cctaacacga tacttttcgc cgtagcgcaa agagtgacaa ggtcactcgg gggaacttga
    19741 aagaccttgg gctttcaagt tagtcatgag acacctatgg tggctgttga cgcccccccc
    19801 cacttaagaa aagtatcaaa aacctttaag gagaaagtat gaaaccaatt atctctatca
    19861 tcatgggctc caaatctgac tggaccacca tgcaaaaaac cgccgaaatc ctcgaccagt
    19921 ttggccttgc ctacgaaaaa aaagtggtct ctgcccaccg cacgccggat ctcatgttca
    19981 catacgctga gaaagcacgc gaacgtggca ttaaaatcat catcgctggt gctggcggag
    20041 cagcccatct ccctggaatg gtcgctgcaa agacgacact tcctgttatc ggcgtacctg
    20101 tcaaatcgcg tgctcttagt ggtcttgatt cgctgtattc aattgtgcag atgccaggtg
    20161 gtgtgcctgt ggcaactatg gccattggag aggcaggagc aaccaatgca gcactgactg
    20221 ctcttcggat cctttcaatt gaggatgaaa caatcgcaga gcagctcagc catttccaca
    20281 aagagcaagg acggatcgca gaggagtcaa cccatgaact caactaaaac aattggaatt
    20341 atcggaggtg gtcagctggg acagatgatg gcgatttctg ccatttatat ggggcataag
    20401 gtcattacac tggatccagc agcggattgc ccagcctcgc gcgtgagtga ggttatcgtg
    20461 gcgccttata gtgatgtgga ggcgctgcgt caattgaccg agcgctgtga tattttgacc
    20521 tatgaatttg aaaatgtgga cgctgacgcc cttgatacag tggtaaagga ggagcagctg
    20581 cctcaaggaa cagagttact tcggatctcg cagaatcgta tttttgaaaa agatttttta
    20641 gccaataaag caagcgcggc agtggcaccc tacaaggttg taacctctag cctcgacttg
    20701 gaaaaccttg acttttcgaa aaaatacgtc ctcaagacag cgacaggtgg ctatgatgga
    20761 cacggtcaag tcgttattcg ctccgaagca gaccttgaag aggctaataa gttggctaac
    20821 actgccgagt gcgtcttgga agaatttgtc agctttgacc gagagatttc cgttattgta
    20881 tctggcaatg gcacagatgt cactgtcttt cctgttcagg aaaatatcca tcggaacaat
    20941 atcctgtcaa aaaccattgt cccagctcgc atttcagaag cagttagcgc taaatcgcag
    21001 gctatggcgg tgaaaatagc agagcagctt aacctatctg gcaccctctg tgtagaaatg
    21061 tttgtggcag gcgacgagat tttggtcaat gaaatcgccc cacgtcccca caactcagga
    21121 cattactcca tcgaagcctg tgatttctcc cagtttgaca cccacatttt aggtgtatta
    21181 ggccagccat taccagctgt caaactccat gccccagcca ttatgctcaa cgtcctcggc
    21241 cagcacatgg aacaagccca acgctacgcc acagaaaacc ctagcgccca cctccacctc
    21301 tatggtaaaa tagaagccaa gcacaaccgc aaaatgggac acgtgacggt gtttaacagt
    21361 caatcagatg aggttgaaga attttaggag gaattaatcc tatgataaaa atcattgttc
    21421 acgcttttat tgaaaatggt gaaacaggtg ttgttgaagt tgtctttgct tcggaaaacc
    21481 aagaatccat ttctgaaaaa atgacggagc tacaaaagca atatccaaac gattaccttg
    21541 ctatctatga tttaccacta gatacagacc tatcgcaatt ggcccactat ccgtcaatag
    21601 cgataggcaa aggggagttt gagtagttaa ggaagattag tatttcggat tgagtgttat
    21661 tgggacaatt tatggctatg cctttcaaaa gattggtcat gatgttgagc atgttgtgag
    21721 aattgagaat cgtaatcaga tttcagaagt tggtaaatga cttaatggat aattctagat
    21781 actgatctcg agcaatcata agagaaatgt tgaaattgta gcttctggag gtgtagaact
    21841 caaaaattat cgtggtgaga tatttccata taaaacttct aagcgtattt cgtctagatt
    21901 gataacatat agataggttt gtacataatg aacttactag atgcatcatg acaaagcaga
    21961 tcttttatat acatgcaaag aggtttacaa tattggtata gtcaactatt gatgccctaa
    22021 cttttaatca caatatagaa attattgcga atagacttta aaagcattac tattaactat
    22081 gtagaaagga aatgagcgct agaattttca aactgaacct gagcggaaag ctcggaattt
    22141 agataaattt cctcggacgt aaatgtccgt ctttagcttt ctaaaattca gttgctttct
    22201 ggctgttctt ggtatcttaa ttatgctaaa ccgttattca cgccctgaga tggcgaagat
    22261 ttggagtgaa gagaacaagt accgtgcttg gttggaggtg gaaatcctcg ctgatgaggc
    22321 atgggctgag ttgggtgaga ttcccaagga agatgtggcg aagattcgcg ccaatgcgag
    22381 ttttgacatc aatcgtattt tggagattga agaagagacc cgtcacgatg tggtggcctt
    22441 tactcgtgcg gtgtctgaaa cgctcggtga ggagcgcaag tgggtccact atggcttgac
    22501 atcgactgac gtggtggata cggcctatgg ctatctctac aagcaggcta atgacattat
    22561 ccgtcgtgac cttgaaaact ttaccaacat tgtggctgag aaggctaagg agcacaaaat
    22621 gactatcatg atggggcgta ctcatggtgt gcacgcggag ccaacgacct tcggtctcaa
    22681 attggcgacc tggtacagtg aaatgaagcg taatcaagag cgttttgagc atgcggctgc
    22741 tggtgttgag gccggtaaaa tctcaggtgc tgttggaaac tttgccaata tcccaccatt
    22801 tgttgaggag tatgtctgtg gcaagctagg cattcgcccg caggaaatct caactcaggt
    22861 cttgccacga gaccttcatg ccgagtactt cgcagtgctt gctagtatcg cgacatcaat
    22921 tgaacgcatg gcaactgaaa ttcgaggcct gcaaaaatct gagcaacgtg aggtagaaga
    22981 gttctttgcc aaaggacaaa agggaagctc tgccatgcct cataagcgta acccgatcgg
    23041 ctctgaaaac atgacggggc ttgcgcgtgt cattcgtggg cacatggtga cagcctatga
    23101 gaacgtggcg ctttggcatg agcgtgatat ttcgcactcg tcagcagagc ggattatcac
    23161 accagacacg actatcctca tcaactacat gctcaaccgt tttggcaata tcgtcaaaaa
    23221 tttgacagtc tttccagaaa acatgactcg taacatgaac tctacctttg gcttgattta
    23281 cagccaacgt gtgatgctta agctgatcga aaaaggcatg acgcgtgagg aggcgtatga
    23341 cttggtacag ccaaagacag cctattcatg ggacaaccaa gtggacttca agccgatcct
    23401 tgaggcagac gaaaatatca ctgcaaaatt aaggcaagat gagcttgatg agctcttcaa
    23461 tccagcttat tataccaagc gtgtcgatgc tattttcgac cgattaggat tataggaaga
    23521 aaacagcgcg tctttttaga ctgtagctaa gcccagattt gtttaaaaag tcttgaaaat
    23581 gaattcctcg gagctaattc tcaaaatgaa gaatagtatt tcaagagagg ctgtcactag
    23641 ctatatcgct taagaaaatg ctctaaaata gacatttttt caatctgaga aggcaatagg
    23701 ccttcttttt ttctaaaaat acagaaatgt tattatagaa tggagtcaaa aaattaataa
    23761 ttaattaaat tgtgtgatat aatgaaagaa atagtgtctt gaagagggaa acatgttaga
    23821 caattttggt gaaaaggtga gagaccttcg gtatcagaaa aaaattacca gagaggattt
    23881 atgtggagat gagtcagaat tatccattcg tcaattggca cgaatagaac tgggccaatc
    23941 gattcccagc ctatcaaagg tggtttttat tgctaaggct ttggacgtta gtgtcggctt
    24001 tttgacagac ggagaggatt tggagctacc gaagcgctat aggagcttaa atatttgatt
    24061 ttaagaacac cgacctatat ggacgatgac aaattaaagc tgcgagaaga gcaatttgac
    24121 gaaatttttg aagattatta tgaccagttg ccagaggaag aaaagcttgt ggtggattgc
    24181 ttgcagtcca taatggatac gttattaacc gagaatatca attttggagt tgggttatta
    24241 caggaatact ttgaacaaac aaaaagtaag actcaattta gagagaatga tctcattctt
    24301 attgagctgt atttagcgta cctcgacatt gcaggaatga atggagagta ttcagataaa
    24361 ggattctatg attctttgtt agacattttg ttaaatcagt ttgaacattt tgaattagag
    24421 gaattattta ttgtcaataa aatagctata ggaatttcct cgttgagcat caaaaacaat
    24481 aagccggaga ttcttgagaa ggttattgta cttagtcaaa aaattatcct caagactcag
    24541 gattttaata gaatgcctat cttaaatttg atagagtgga aatatgctct aatgaagaaa
    24601 aaagacatag aaatggccaa aaaatgctat gctaaggcat gcctgtttgc tcaattaaca
    24661 ggagatcagt atttggaaaa gaaattgaga gaagaatggg gtaaagatat aaaacgatat
    24721 caataggaca aaaatgtcat ttttatcaaa aatggaataa tatataatct ttatataaca
    24781 aataattgat taaaggagtt ccatttatat gtttaaaaaa taccaatact atctgttttt
    24841 agctgcttta tttctacttc attctgccca attacttagt gatattgact ggtggcgtgt
    24901 tggttaaagc taaatcatct atttatgcta taatagctct atgacaagaa ttttagataa
    24961 tgatctgata ggcgatgaag gatctgttga gaggacacta cgtccacagt atttacgtga
    25021 gtatattggt caggataggg ttaaagacca gctgatgatt tttattgagg cagccaagag
    25081 gcgtgaggaa tccttggatc atgtcctgtt atttggttcc ccaggcttgg gtaaaacaac
    25141 gatggccttt gtcattgcca atgaattggg agttcatctc aagcagacct ctggcccagc
    25201 cattgaaaaa gctggtgatt tggtggcaat tttgaatgat ttagagccag gagatgtcct
    25261 ctttattgat gaaattcatc gtatgccgat ggctgttgag gaaatcttgt acagtgccat
    25321 ggaggatttt tacattgata tcatgattgg cgctggagac actagccgga gtgtgcattt
    25381 ggagctgcct ccctttacat taattggagc aacgactcgt gcaggcatgc tgtcaaatcc
    25441 tttgagggct cgttttggga ttactgggca tatggaatat tatcagacag ctgatttaac
    25501 agagattgtg gagcgtacag ctgatatttt tgacatgaca atcaagcatg aggccgctta
    25561 tgaactggca cgcaggagtc gtggaacccc tcgtattgct aatcggctgt taaaaagggt
    25621 gcgtgattat gctcaaatta tgggtgatgg aatgattacg actcaaatca cagataaggc
    25681 tctaacgatg ttagatgtgg atcaagaagg tttagattat gtggaccaaa agattcttcg
    25741 taccatgatt gaggtgtacc aaggagggcc ggttggtctt gggactctat ctgtcaatat
    25801 agcagaggag cgagatacag tagaagacat gtacgagcct tatttaattc aaaagggttt
    25861 tatcatgcgt accagaacag gccgagttgt caccgaaaaa gcctatcagc acttaggcta
    25921 tccctatgaa aaaaccatta agacataaat agctatgtaa gacttgattc ctttgttttt
    25981 accggtgtca agtcttttgt attgtcaata gcttactgag taaaaaagta aaacgatgtg
    26041 aggtgagggg tgattggtca gggaagcaga ggtgctttca ctagacaaag cattaaaaaa
    26101 catttttaga tcaattgaac gaaaattata agagcgattt ctccttttgg ccctataatt
    26161 ttgctataat aggtaaaagg agtttttcat gaaaaaagta tgctttgttt gtcttggaaa
    26221 tatttgtcgt agtcctatgg ccgaatttgt catgaaaagt atggccagtc ctgatgagct
    26281 acaggtggag agtcgtgcaa cctctggctg ggagcatggc aatccaattc atcatgggac
    26341 acaatcgcta ttacagcaat atcagattag ctatgatacc aagaaaacct ctcagcaaat
    26401 caccagcttt gactttgaag cctttgacta tattatcgga atggatagcc ataatatcag
    26461 agatttgaag caaatgtcca agcatcagtg ggattccaag atccatcttt ttattgaagg
    26521 aggcgttccg gatccttggt atacaggaga ttttgaagaa acctaccgct tggttaaagc
    26581 gggctgtcag cattggttga gtcaaatcag cgctgaacat gaatcacatg tggaaataga
    26641 tgagtaatag taatgaaagc aataataaat aacattcaaa aatggcagat cactcggaca
    26701 aagctagaga ttatttcagt ccttgtgatt attgtctgtg gattgtcggt ttttaccttg
    26761 accatatcct caaaagcaag cttgacctat gacaatgggc aaatcaagta caccggctat
    26821 gtccttaatc atagaatgaa tggtaaaggg aaattggttt accctaatgg cgatacctat
    26881 gttggggatt ttaataaagg tgtctttgat ggagaaggaa cgtttacagc tagtacaggg
    26941 tggtcttaca gcggacaatt taaaaaaggt caggctgatg gcaagggtac tttgaaggcg
    27001 aaggattcaa aggtttacaa aggaaccttt aagcagggga tatttcaaaa atgaggataa
    27061 aatggttttc gtttattagg gtaacaggtc ttttgctggt gttgctctat cactttttta
    27121 agcatacttt ttcaggaggc tttgttggcg ttgacatctt ctttactttt tcaggctatt
    27181 tgattacagc cttgttgatt gatgaatatg tctcaaaaca aaccattgat gtggttgctt
    27241 tttttagaag gcgtttttat cgtattgtac cgccgcttgt cttgttaatt ctcttgacaa
    27301 ttccctttac ttttttagtc aaaagtgact tcattgctgg tatcggtcag caaatagcag
    27361 ctgccctagg gtttacaaca aatagttatg agctactgac aggcagtagc tatgaaagtc
    27421 aattcattcc gcatctgttt gtgcatacct ggagcttggc cattgaggtg catttttatt
    27481 tgctttgggg gctgttggtt tggttattag ctaaaaaagg ctacagtcag aagaaattta
    27541 gaggcattct gtttttaatt tcttccgcag tgttcacgct tagctacttc agcatgttta
    27601 tcagagcctt ctttgtatca gatttttctt ctgtttactt ttcaacgctt tcacacagct
    27661 ttcctttctt tttaggagcg atgtttgcaa ccatgacggg aattaaggac acgactgttc
    27721 gctttcaaaa gaatgttaag ctgtggccaa ggctacatgt tattggagtg atggctggcg
    27781 cttttgctct gttgttgttt ctaacgcttg tgttagattt taaccatatc tttacctatc
    27841 ttttcggttt tgtcttagcc agtctttttg cttcggtaat gatttatgct gcgcgtgttt
    27901 tgagcgatca aacaccaacc tggcaggaac cactgcttgt gacctatctt gcggatatta
    27961 gctatgggat ttatttattc cattggccat tttacattat ttttacacag ctgatgtcta
    28021 actggctggc agtgatctta acggttttct tttcagtagt gttttcaacg ctttcttatt
    28081 acattattga gcctttgatt caaggcaaga caccacagct ttttggttta gcaattgatt
    28141 gtaatcccta taagaaatgg ttatcagggc ttgctttagg actctttttg ttgatggttg
    28201 gtacctgttt gacagcacca agggtcggta attttgagac ccagctttta gtagattcct
    28261 tgcagcaatc tcaaagtaat ctcaataaga cacatacttt ggcagcagga gatgcgcatg
    28321 ctcttagtga tgttagcatt attggtgact cagttgcctt gaggtctagt gacgcttttt
    28381 caaaattaat gccgactgct caactagacg ctgctgtcag ccgcaatttc agtgaagcct
    28441 ttgagctttt tgaaaatcat atccaatcca agagcttatc aaaaacaacg gttttagctg
    28501 ttggtgttaa ttctctttat aattatgcgc aggatattca aggctttatt tatgcactac
    28561 caaaggggca tcgcttggtg attgtgtcgc cctatgatgc taagaatgca gcacaggtag
    28621 cagaggctag agagcatttg ttgcagctag ctaaaaaata tagctatgta acagttgctg
    28681 actggtacaa ggcggcagtc gaaaatccca atatctggta tggtagtgat ggggtccact
    28741 acaataacga cgccaaatta aaaggtgctg acttatatgt ctcaacgatt caggcggctg
    28801 ttgagcgagc agcaaaaaaa gatgctaaat agtggtgcta acaacaattt gttaagaatt
    28861 aataacgaag gcttggtctt acaaacagat caagcctttt catgatgtga tttttagatc
    28921 gtcttgcgcc ctttagcgcg agataaagct ccacctgtta gacagtgtca ttattggctg
    28981 ttattgctga cggtgacgtg cttttaaaaa cggatcatta aataatttag cctgatctaa
    29041 aaaagaaagc gctttcggaa caaagtgaat gcgtcagcca ttatttcaga aaaaatccac
    29101 caagccaaac cccttgttat caaagagttt cggaaattga ttgaaaaaac atcacaattt
    29161 tattgtgaaa tgatttacaa aatgccaaaa aatgatataa tatttttgta aacaaaattg
    29221 tgaaactttt aacaaggtaa aggagtctca aatgactgaa aaaaatagta ctgttgaaac
    29281 aacatctgtt gccgcaacaa ttgacgctct tgttcaaaaa ggtttagtag cgcttgataa
    29341 aatgcgtcag ttaactcaag aacaggttga ctacattgta gcgaaggcct ctgttgctgc
    29401 tttggacgca catggtgagt tagctaagca tgcctatgaa gaaactggtc gcggagtttt
    29461 tgaagataag gctaccaaaa accttttcgc atgtgagcac gttgttaata acatgcgtca
    29521 ccaaaaaaca gtaggtatca ttgaagaaga cgatgtaaca ggtttgacct taattgctga
    29581 gccagtaggt gttatttgtg ggattacccc aacaactaac ccaacgtcaa cagctatttt
    29641 taaatcttta atctccttaa aaacacgtaa ccctattatt tttgccttcc acccatcagc
    29701 tcaagaatca tcagctcatg cagcacgcat tgttcgtgat gcagccattg cagcaggagc
    29761 tcctgaggac tgtgttcaat ggattgaaac cccatcacta gaagcaacta acgctctgat
    29821 gaatcatgat ggtattgcaa caatccttgc aactggtggt aatgctatgg ttaaggcagc
    29881 ctactcatgt ggtaagccag ctcttggggt tggtgctggt aacgtgcctg cctatgttga
    29941 aaaatccgct aacattcgtc aggcagcaca cgatattgtc atgtctaaat catttgacaa
    30001 tggtatggtt tgtgcttctg agcaggctgt tattatcgac aaggagattt atgacgagtt
    30061 tgttagtgaa tttaagtctt accacactta ctttgtcaac aaaaaggaaa aggctctgtt
    30121 agaggaattc tgctttggtg ctaaggctaa cagtaaaaac tgtgcaggtg ctaagctgaa
    30181 ccctaatatt gttggtaagc cagcagcttg gattgctgag caggcaggct ttacagtacc
    30241 agaaggaacg aatatccttg cagcagaatg taaggaagtt tctgaaaatg agccattaac
    30301 acgtgaaaaa ttgtcaccag ttatcgctgt tttgaaggct gaatctcgca cagatggtgt
    30361 tgaaaaggct cgtcaaatgg ttgaatttaa cggacttggt cactcagccg ctattcatac
    30421 tgctgatgca gacttagcta aggaatttgg aacaaaaatt cgtgctattc gtgtgatttg
    30481 gaattcacct tctacatttg gtggtatcgg tgatgtttat aatgccttcc taccgtcatt
    30541 aacattgggc tgtggttctt atggacgtaa ctcagttggt gataatgtta gtgctgtaaa
    30601 tctcttgaac atcaaaaaag taggaagacg tagaaataat atgcaatggt ttaaagttcc
    30661 ttcaaaaaca tacttcgagc gtgattcaat tcaatacctt caaaaatgtc gtgacgttga
    30721 gcgtgtgatg attgttaccg accacgctat ggttgagctt ggcttcttag atcgtatcat
    30781 cgagcagctt gaccttcgtc gtaataaggt tgtttatcaa atttttgcag atgttgagcc
    30841 agatcctgat atcacaacgg ttatgaaagg tactgagctg atgcgtacct tcaagccaga
    30901 tacgattatc gctcttggcg gtggttctcc aatggacgct gcaaaggtaa tgtggttatt
    30961 ctatgagcaa ccagaggttg acttccatga tcttgttcaa aaattcatgg atattcgtaa
    31021 acgtgccttc aagttccctg agcttggtaa gaaaacaaaa tttgtggcta ttccaacaac
    31081 ctcaggtaca ggatcagagg ttacaccgtt tgctgttatc tcagataagg ccaacaaccg
    31141 caagtaccca attgctgact attcattgac accaacggta gccattgttg acccggcgtt
    31201 ggtgcttaca gtaccaggct tcattgcagc tgatacaggt atggacgtgt tgacccacgc
    31261 aaccgaggct tacgtatcac aaatggctaa tgactttaca gatggtttgg cccttcaagc
    31321 cattaagatt gtctttgaaa accttgaaaa atctgttaag gaagctgact ttgagtcacg
    31381 tgaaaaaatg cataatgcct caacaatggc aggtatggcc tttgctaatg ccttcctggg
    31441 tatttctcac tcaatggctc ataagattgg tgcacaattc catactgttc atggacgtac
    31501 caatgctatc ttgcttccat acgttattcg ttacaatggt acccgtcctg ctaaaacagc
    31561 aacatggcct aagtacaatt actatcgcgc cgatgaaaaa tatcaagaca ttgctaagtt
    31621 gctaggactt ccggcatcta ctccagaaga aggtgttgaa tcttatgcta aagctgttta
    31681 tgatcttggc tgtcgcttag gcattaagat gaatttcaga gatcaaggaa ttgatgagga
    31741 agaatggaag gcacacactc gtgagcttgc ttatcttgcc tacgaggatc aatgctcacc
    31801 tgctaaccca cgcttgccaa tggttgagca catggaagaa atcatgaatg atgcttatta
    31861 tggttacgca gagcgtccag gacgtcggaa ataatatcaa tcattaatag taaaaatagg
    31921 agctgcttgg cttctatttt tttatctagc tatgaaaagg gctgtgttag atgaaaaagt
    31981 cggcagtgcc ttgtgttgag atagcttaac tcaggggtag tttctcagat atcatataaa
    32041 gcttttaaga caatggtttt acagagcatt ccatcagagg gggaagcttc atttgccata
    32101 ttcataaagt ggctgatagt tacgacttag ctgcacttag caattagctg aagaaaataa
    32161 catgttgcgt ctatctgatg agctttattt tctaataaaa caaggagtga ttgctttttt
    32221 aatgatgtta atagcgttaa aaacctttat atatcaaaca aaaaccaaaa taatggtatt
    32281 gtcagacttt ttctaaaatt accctttatt aattgacaaa gagggtgtaa aaaattatac
    32341 taaaaatgta atcgattaca ttttctagac taaatttgga gacgttttat gaaagcagct
    32401 acatatgttg ctccaggtca gctggagctt attgatcaac caaaaccaga gattcttgct
    32461 ccgacagatg ctgtggttcg tttattgaaa acaacaatct gtggaacaga cttacatatt
    32521 ttaggtggag atgtcccaga gactactcat ggtaccattt taggtcatga aggtattggt
    32581 attgtcgagt cagtcggctc tgcagtgaac aactttaagg taggtgataa ggttattatt
    32641 tcctgtatca cagcctgtaa tacctgctat tattgtaaaa aaggaattcc tgctcattgt
    32701 gaaagcggtg gctggattct agggcatttg attaatggga cacaagcaga gtatgttcat
    32761 attcctcaag cagatggcag tctttatcat gctcctaaaa ccgttgagga tgatgccttg
    32821 gttatgctgt cagacatttt cccaacttcc tatgaaatag gcgttcagtc tgcaaaggta
    32881 aagccgggtg atacagtgtg tatcgttgga gcaggtccta tcggactagc agctctttta
    32941 acagcacaat tttattcacc agctaagctg atcatggttg acttgtcaga atcacgttta
    33001 gaagcagcta agcgctttgg agcaacagat acgatttgct ctggtgacct tgatgatatt
    33061 gtcaaaaaag tccatgaatt aactgatggt cgaggtgttg atgttgccat tgagtgtgta
    33121 ggctatcctg ctacctttga tatttgccaa aagattattg ctattggcgg gcatgtttct
    33181 aacgttggtg tccatggaaa accagttagt ttggacctac aggacctatg gatcaaaaac
    33241 attacaatgt caactggcct agtaaacgct aatacaacag aaatgctatt gaatgtgttg
    33301 aaatctggta agattgatgc aactaagatg gtaacacatc actttaagct gtcagaggtt
    33361 gaaaaagcct atgaggtctt taaaaatgcc ggcagtaata acgcccttaa agtgattatt
    33421 gaaaatgaca ttacagccta aaggaataag gtataaatag ataaaagtga caacagcatt
    33481 tggaatggtc tagatgctgt tttttagcca acttaactgg ttaagtttat tttcagaaaa
    33541 ctttcaagaa attggttgac aaaccttgtg aaaaagtata caatacaaat tgtaaacggt
    33601 tgcaaaaata gataaaccga gacttagaaa ttggaggcat cctatgaagg ctgtagttgt
    33661 taaccaaacc agcagtggtg tagaggttgt agagcatgat gtaccatcaa tcggtcatgg
    33721 agaagctctt gttaaagtag aatattgtgg cgtatgtcat actgacttgc atgttgcgca
    33781 tggtgatttt ggtcaggttc cagggcgtat cctcggtcat gaaggtatcg gtattgtcga
    33841 aaagctaggt gaaggcgtta cctccttaaa ggttggtgat cgtgtatcaa ttgcttggtt
    33901 ctttgaaggc tgcggtcatt gtgaatattg tacaacaggt cgcgagactc tatgccgttc
    33961 agtcaaaaat gctggctatt cagttgatgg tgggatgagt gagtatgcag ttgttacagc
    34021 tgactatgct gtgaaagtgc cagatggtct tgacccagct caagcatcat caattacctg
    34081 tgcaggcgtt acaacctata aggctatcaa agaagcaggt gccgctccag gacaatggat
    34141 tgttatcttt ggtgccggtg gacttggtaa cctagctgtt cagtatgcta aaaaggtttt
    34201 caatgctcat gtcgtagcag tggacattaa caatgataag ctagagctgg ccaaggaggt
    34261 tggagcagat atcgttgtca atggtaaaga aatcgaagat gttgccggct atatccaaga
    34321 aaaaacaggt ggtgctcatg gcgttgtggt aaccgctgtt tctaaagtag cctttaacca
    34381 agctattgat agtgtgcgtg caggaggaac tgttgttgct gtaggacttc catcagaata
    34441 catggaatta tctatcgtaa agactgtcct agacggaatc aaggtagtcg gatcacttgt
    34501 gggaactcgt aaagacttgg aagaagcctt tgcctttggt gcagaaggtc tggttgtgcc
    34561 agttgtagaa aaggttccag ttgagactgc tccagaagtc tttgacgaaa tggaacgtgg
    34621 tctcattcaa ggaagaaagg tattggattt cacgctttaa ggctgatttc agaaaaagtc
    34681 agcagccaga caagctgatt gtcccaaatg atgaataaag tccttagaat taattttcta
    34741 agggcttttt tggtgaaact aactggtaaa aaaagcttgg tatctaaaga tgtaaaagag
    34801 ccagctagtt attaatacca tgattgcccc ttgaaagaca gtaccagaga aagttggaca
    34861 tattgtaacc tctgatagag atactgggtt tgaacaatat tagagattaa cacaggaact
    34921 caatctagaa gtttatttct ctgctcctca caccccttga taacgtagga caaatgaaaa
    34981 taccaatggg ttaatcaaag agtagtttcc taaaggaact gacttgactg atattgagag
    35041 ctctatcata taagagtggg aagataaatg aaatgatcgt tctagaagat gtcctaactg
    35101 gaaactacct tataaactct tttatggaaa agcgttgcac ttaatttgac aattcgtctt
    35161 cacaaatttt aggaagcact gtaggaaaaa agaataatga cataacatat tgctaaaaac
    35221 atgggttata agctaaatta ttatctacgt ttttagtaac aaggtagtat gatttaaaat
    35281 atagatgaaa aatgttgtgt cccgaataag ggaagttttt taggatacga tacttgtaca
    35341 ttataattta tttataaaat cttttaggtg gatttatgaa agaaattgta agaagtcata
    35401 gattgttata tgtaatagta gcttttttta gtgtaatcag tgcattttta atgaccttat
    35461 tttctattca actgggaaaa atactagata gtatatctaa ttcaagtagt gaattattgt
    35521 ttcagatagt agtgtgtgta tgtaccataa tggcatggtt tataatgata tggtcctatt
    35581 cttattttaa gagttattat gtaaaaaagg tcattttaga tttaaaggag aggcttttta
    35641 taggttattt attacgggaa tttaatgaaa ttgatacttg tgatcgatat aattcggatt
    35701 ttctaaacaa tgtaacaaaa aatattgata taattcagga gaatttattg gttcctagag
    35761 tggctgtgat tgttgatctg gcttcaatgg ttacgagtgt agtagctatt gtacttatag
    35821 aatggcgatt ggccctagta tttttattgc tttctattgt aactgttttt ctatctcaaa
    35881 ttcctggaaa gttaatgagt aaagcaactc gatattattc tgaaaaaagt aatcactatt
    35941 tagcagaaat gactagtttt attgagggat ttgaacagat taaattattg aatattcaaa
    36001 aatggataca aaaaatcgaa caaaatacta ctttagaatt tgaagattct agacagaaat
    36061 atcaatacag aaaagattta gcttcaaata caggaatgtt tttgagcttc ttttctcaag
    36121 tagcctgtat ggttgctggt atattttttg taaggaataa tctactaaca gttggactat
    36181 tagtggccag tattcagtta ttaaatggag tgtttggccc tctacagtct ttcctttaca
    36241 ataaaaattt gatcaaaagc acaggtacta ttttaacaag tattcaagaa gttctagata
    36301 aaacaaattt tgttaatggt tatatagaaa ataagacttt ttatgaagga gacatctcca
    36361 gcatttcgat aaataattta acttatcaag ttgaaaatag aaaaatattt acta
//
LOCUS       DARYXZ010000021        35714 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYXZ010000021 DARYXZ010000000
VERSION     DARYXZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35714
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..693
                     /locus_tag="TV186_000907"
     CDS             <1..693
                     /locus_tag="TV186_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532312.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TV186_000908"
     CDS             complement(1204..2832)
                     /locus_tag="TV186_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1532313.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TV186_000909"
     CDS             complement(2837..3568)
                     /locus_tag="TV186_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532314.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TV186_000910"
     CDS             complement(3605..3862)
                     /locus_tag="TV186_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1532315.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4234..5682
                     /locus_tag="TV186_000911"
     CDS             4234..5682
                     /locus_tag="TV186_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1532316.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     GEQGPRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGPRGEKGEQGPRGEKGEQG
                     QRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGENGEQQPKGD
                     QGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQSTPSKKAVL
                     PATGEASHPFFSLAALSVIASAGLLTLKRKKS"
     gene            complement(5864..7852)
                     /gene="tkt"
                     /locus_tag="TV186_000912"
     CDS             complement(5864..7852)
                     /gene="tkt"
                     /locus_tag="TV186_000912"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1532317.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(8236..8880)
                     /gene="fsa"
                     /locus_tag="TV186_000913"
     CDS             complement(8236..8880)
                     /gene="fsa"
                     /locus_tag="TV186_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1532318.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGAHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            complement(9054..10559)
                     /gene="glpK"
                     /locus_tag="TV186_000914"
     CDS             complement(9054..10559)
                     /gene="glpK"
                     /locus_tag="TV186_000914"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL1532319.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            complement(10899..11492)
                     /locus_tag="TV186_000915"
     CDS             complement(10899..11492)
                     /locus_tag="TV186_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL1532320.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            complement(12160..12360)
                     /locus_tag="TV186_000916"
     CDS             complement(12160..12360)
                     /locus_tag="TV186_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1532321.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            complement(12419..12574)
                     /locus_tag="TV186_000917"
     CDS             complement(12419..12574)
                     /locus_tag="TV186_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1532322.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            complement(13080..13946)
                     /gene="rsmI"
                     /locus_tag="TV186_000918"
     CDS             complement(13080..13946)
                     /gene="rsmI"
                     /locus_tag="TV186_000918"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL1532323.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            complement(13951..14274)
                     /gene="yabA"
                     /locus_tag="TV186_000919"
     CDS             complement(13951..14274)
                     /gene="yabA"
                     /locus_tag="TV186_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL1532324.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            complement(14267..15067)
                     /locus_tag="TV186_000920"
     CDS             complement(14267..15067)
                     /locus_tag="TV186_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1532325.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            complement(15064..15939)
                     /locus_tag="TV186_000921"
     CDS             complement(15064..15939)
                     /locus_tag="TV186_000921"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL1532326.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            complement(15953..16588)
                     /locus_tag="TV186_000922"
     CDS             complement(15953..16588)
                     /locus_tag="TV186_000922"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL1532327.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            complement(16904..17188)
                     /locus_tag="TV186_000923"
     CDS             complement(16904..17188)
                     /locus_tag="TV186_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL1532328.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            complement(17189..17635)
                     /locus_tag="TV186_000924"
     CDS             complement(17189..17635)
                     /locus_tag="TV186_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1532329.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            complement(17740..18330)
                     /locus_tag="TV186_000925"
     CDS             complement(17740..18330)
                     /locus_tag="TV186_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL1532330.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            complement(18561..19190)
                     /gene="upp"
                     /locus_tag="TV186_000926"
     CDS             complement(18561..19190)
                     /gene="upp"
                     /locus_tag="TV186_000926"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL1532331.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            complement(19340..20971)
                     /locus_tag="TV186_000927"
     CDS             complement(19340..20971)
                     /locus_tag="TV186_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL1532332.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAG
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            21057..22502
                     /locus_tag="TV186_000928"
     CDS             21057..22502
                     /locus_tag="TV186_000928"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL1532333.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            22762..23541
                     /locus_tag="TV186_000929"
     CDS             22762..23541
                     /locus_tag="TV186_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532334.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            23566..24504
                     /locus_tag="TV186_000930"
     CDS             23566..24504
                     /locus_tag="TV186_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1532335.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            24514..25539
                     /locus_tag="TV186_000931"
     CDS             24514..25539
                     /locus_tag="TV186_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1532336.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            25536..26534
                     /locus_tag="TV186_000932"
     CDS             25536..26534
                     /locus_tag="TV186_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1532337.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(26639..27292)
                     /locus_tag="TV186_000933"
     CDS             complement(26639..27292)
                     /locus_tag="TV186_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL1532338.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(27359..28294)
                     /locus_tag="TV186_000934"
     CDS             complement(27359..28294)
                     /locus_tag="TV186_000934"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL1532339.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            complement(28794..29585)
                     /gene="pflA"
                     /locus_tag="TV186_000935"
     CDS             complement(28794..29585)
                     /gene="pflA"
                     /locus_tag="TV186_000935"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL1532340.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            complement(29662..30996)
                     /locus_tag="TV186_000936"
     CDS             complement(29662..30996)
                     /locus_tag="TV186_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL1532341.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            complement(31124..31681)
                     /locus_tag="TV186_000937"
     CDS             complement(31124..31681)
                     /locus_tag="TV186_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1532342.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            complement(31691..32476)
                     /locus_tag="TV186_000938"
     CDS             complement(31691..32476)
                     /locus_tag="TV186_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL1532343.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            complement(32489..33412)
                     /locus_tag="TV186_000939"
     CDS             complement(32489..33412)
                     /locus_tag="TV186_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL1532344.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            complement(33603..34253)
                     /locus_tag="TV186_000940"
     CDS             complement(33603..34253)
                     /locus_tag="TV186_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL1532345.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            complement(34243..34821)
                     /locus_tag="TV186_000941"
     CDS             complement(34243..34821)
                     /locus_tag="TV186_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1532346.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     regulatory      complement(34894..35019)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
BASE COUNT        10496 a         8496 c         7079 g         9643 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaaacgaaac tacggagaca aactaatcag
     4141 cagctatttc ttacatttag ctagcgtgtt aagatagcta ttggaaaaga tttttaggaa
     4201 tacttcatat ttctatcatc aaaggagaga gaaatgataa ataaaagaaa gaaaaaactt
     4261 atctacaggt atggtgtctg ctcggcagca gttatcctag cagcgcttgc tagcctagga
     4321 acatgtaaag aagcaaaagc attatctggt ccgccaggat acccacttac tcgtgatttc
     4381 tcccgtaact tcctagaaga aaatactgca aaatatttag atcaattaag agaacatcta
     4441 cagcacagat ttagtgaact tgagagctta acaagaaaat tagagaaaga aggcggtacc
     4501 cgaggtccag cagggcctcc ggggccagcc ggacctaaag gggaacgtgg cgaaccaggg
     4561 cctgttggac ctatgggacc tagaggtgaa caaggtccta aaggcttaga cggagcacgt
     4621 gggcccgagg gacagcaagg aaaacctgga cctgtcggac ctcaagggcc ggcaggtcca
     4681 gcggggcaaa aaggggaaac cggacctcag ggacctcgtg gagataaggg cgatactgga
     4741 gaaactggaa agcaaggacc agcaggagaa cgtgggccag ctggacctca gggaccgcgc
     4801 ggagacaagg gtgaaaacgg tgcacccggt gagcaaggcc ctattggtcc aaaaggtgag
     4861 actggaccta aaggtgacaa gggagaacgc ggcgaaaagg gcgaccaagg tcaacgtggt
     4921 gaaaagggcg accaaggtca acgtggtgaa aagggcgacc aaggtcaacg cggtgaaaaa
     4981 ggcgagcaag gccaacgtgg tgaaaagggc gagcaaggcc aacgtggtga aaagggcgag
     5041 caagggccac gcggtgaaaa aggcgagcaa gggccacgcg gtgaaaaagg cgaccaaggt
     5101 caacgtggtg aaaagggcga ccaaggtcaa cgcggtgaaa aaggcgagca aggccaacgt
     5161 ggtgaaaagg gcgagcaagg gccacgcggt gaaaaaggcg agcaagggcc acgcggtgaa
     5221 aaaggcgagc aaggtcaacg cggcgaaaaa ggcgaccaag gtcagcgcgg tgaaaaaggc
     5281 gaccaaggtc aacgtggcga aaaaggcgac caaggtcaac gcggtgaaaa aggcgaccaa
     5341 ggtcaacgtg gcgaaaaagg cgagcaaggt caacgcggtg aaaatggtga gcaacagcca
     5401 aagggtgacc aaggaaagga taccaagcca tcagttccaa aggcaccaga atcaccaaaa
     5461 atgccagaga agccacaggc tcctgaaaag gctcctgcac cgaaagctcc aaaggcttca
     5521 gagcagtcag ctagccctaa ggcaccagca cctcagtcaa caccaagcaa aaaagcagtc
     5581 ctaccagcta caggagaggc aagccatcca ttctttagtc tggcagctct tagcgtcatc
     5641 gctagcgcag gtctgctaac cctaaaaaga aagaaaagct aagccagcta tttgacaata
     5701 gcttctagca actcgggata gatctgcaag gctgagcagt agcactatta aatctgaaac
     5761 aaaaacgcat gacgtcctcc ctaaaaaggg ttgaacatca tgcgtttttt tgtctaataa
     5821 tgccgaaagc aagcctagat aaggcctgct ccagcttaat cacttatgat aaggatttgt
     5881 acaattcagt agcatgctct actgtaaagc catattcttc aaagatacga ttgcccggtg
     5941 cagaagctcc ccatgtatca atggtcagtg ttttccctgc aaggccaacg tattttgccc
     6001 agccaaagct tgagcctgct tcaatagcta gacgttttgt cactgctgct ggtaggattt
     6061 cctccttgta ggaagctggc tgctcatcaa agatattttg tgatggcatt gataccacac
     6121 gcacatggat accatctgct gcaagagcgg cttgagtatc cattgctagc ttgacttcag
     6181 agccggttgc aatgataatc ccatcaaggt caccctttgc ctctgacagg atataagctc
     6241 ccttattaag gccatcttct gccaattcct tagtaccttc aagtacagga aggttttgac
     6301 gtgttaagac aagcattgtc ggacggtctg tctcagcgat cgcacgcttc caagcagcgt
     6361 ttgtttcatt gccgtcagct ggacgaataa cgttcagatt tggcattgat cgaacactag
     6421 ctagctgctc gattggctca tgggtcggac catcttcacc aaccgcgata gaatcatgcg
     6481 tcatgacata aaccgttggt agctgctgca aggctgccat acgaaccgct ggcaataggt
     6541 agtttgaaaa gacaaagaag gttccgccat aaacacgtgt tccaccatga agggcaatac
     6601 cgttcatcgc tgctgccatt gcaaattcgc gtacgccaaa ccagatgtta cgaccagcat
     6661 aatgacccgg ctggaagtct gtctcagcct taaccatggt attgttagag gcagaaaggt
     6721 cagctgagcc tccccagaag gctggcacct gctcagagat ttgttggata gcctgctggc
     6781 tagaaacacg actggctact gctgtgccaa gctcgtgagc ttgcaactca acctctgccg
     6841 cctcattagc aaaggctttt ttgtattcgg ctgctaactc agggtatgct gcttcataag
     6901 ctgcaaatag gtcattccat gcctgctcag cctgctcacc acgcgcctga aggccttgtc
     6961 taaagcgctc agtcacctct tgcggcacct caaaatcagc atgggtccat tgataagatt
     7021 tcttagcaaa ggcaatgcct tctgcaccaa gcggagcccc atgaacagct gaagttcctt
     7081 gcttttcagc accaaagcca atgattgtct ttacttcaat aatggttggc ttttcagtct
     7141 ctgccttagc ttcctcgata gctttagcaa tggcctctag gtcgttgccg tctttaacaa
     7201 ggatatgctg ccagccgtaa gcttcaaaac gccccttgac gtcttctgtg aaggccattg
     7261 aggttgggcc atcaagcgaa atatcgtttg aatcatatag caagacaagc ttaccaagct
     7321 tcaagtgacc tgccagactg gctgcctcct gactgacacc ctccataagg tctccgtcac
     7381 catttagagc ataggtatag tggtctacaa tatcaaagcc aggtctattg aacttagctg
     7441 ctaagtgtgc ctctgccata gccataccaa ctgcattggc aactccttgt cctaaaggcc
     7501 ctgtggttgc ctcaacgcca tctgtatgat tgacctctgg gtgacctggt gttttagagc
     7561 cccattgacg gaagttctta agatcctcaa tagacacatc atagcctgct aggtgcaaca
     7621 ggctgtaaag catggcacta ccatgacctg ctgataggat aaagcggtct ctatttgacc
     7681 aacggcggct tgtctttgga ttgactgtca taacatgatt ccatagcaca taagccatcg
     7741 gcgccgcccc catcggcaaa cctggatgcc cagaatttgc tgcttgaata gcgtccattg
     7801 atagagtacg aacagtatta actgccagct gatcaattgc atcaaatgtc ataagtaaaa
     7861 cctctctgtg tattacaact aaaaattaaa cgttttccat tgtctattgt aacataaaag
     7921 taaactgatt tttaacaaaa tcctataaag tccttaaatt cttatctagc aataagcatt
     7981 gctgttccta gctttttgtg attgacagct gtcttagata gagcacctat gctcataaga
     8041 aaaagcaagc ctagctgttg ccagctaagc aagcattcct ctttggtacc tccctttggc
     8101 tacagtaagc gccagctgcc tgttaattct agcgcaacag caaagcacca gctgatcctg
     8161 ccacctacaa atagctaatc ccaaactaac cgctacagcc acattagaat ataaggagag
     8221 ctctatgctc ttagcctatt ttttaaagga agcccaatcc tccataaagg tctttaagcc
     8281 atttgttgtc aatgggtgct cagtcatctt cgcaaataat ggatctggaa tggttgcaat
     8341 gtgtgcccct agctgtgcaa cagcttcaac atgggcagct gtccgaatgc tggctgcgat
     8401 gatttctgct tggaagccat acaaatcaat gatcccacgc aaatcactaa taagctgata
     8461 aggatctgct ccaatatcct ctaagcgacc aataaatgga ctgatatagg tcgcaccagc
     8521 cttcatggcc attagtccct gactaactgt aaaaataagc gtcacatttg ttttgatgcc
     8581 ttcttgtgac aagacattag ttgcttttaa gccctctgtc gtcatcggaa ttttcacgac
     8641 cacattgtca tgccacttgg caatgttcct agcctctgca atcatttcct ctgcggttag
     8701 tccggtgacc tctgcactga tagggccgtc cacaatctca cagatttcct tgataactgt
     8761 ctcaaaatca cgaccctcac gcgagataat gctagggttt gtggtaacac cgtccacaac
     8821 accaagctca ttaatcgcac gaattgcctc tacatttgct gtgtctaaga aaaatttcat
     8881 cttaacctcc gttaattagt ctgttatcag tcattgaaca gcatgacgct gtttaccgtc
     8941 tacattatca ttataaaagt cactcttagg atataaaaga ccaagtatca cacagtctag
     9001 tgttcaaaac tagacctagc tatgggactc tgtttcttta aaaggcttga ttcttacagc
     9061 tcctctgcaa aaaactgtgt ggctttgaca gctcttttcc agccttgata taacttttct
     9121 cggcgagact cactcatgct tgctttaaac agctgacctg tagcatttaa ttgctttagt
     9181 gtctccatgt ccttccagta gcctacagca agcccggcta aaaaggctgc tcctagagct
     9241 gtggtttcaa gattttcagc acgagcaata tcaatcccta aaatatctgc ctgaaactgc
     9301 atgagcatgt tattcatagc cgctccgcca tcaacacgta attgctggat agtgatccct
     9361 gagtccacct gcatggtatc aatcacatct ctgacctgat aagcaataga ctgtagggta
     9421 gccttaacaa aatcctcttt tgttgttcca cgcgttaagc caaatactga gccgcgtgca
     9481 ttggaatccc aataaggagc gccaagacct gtaaaggctg gtacaacata tacctcatca
     9541 gcattggttg aagccaaggc tagctgttca gactcaaaag aggtttttat cattcgcaag
     9601 ccatctcgta gccattgcac agcagagcca gcaataaaga tagacccttc taaggcataa
     9661 taaaccttgc cattaatacc atatccaatc gttgttagca ggttgctgct ggataattga
     9721 gcctcttgac cagtattcat gatgataaaa gagcctgtgc cataggtatt ttttaccata
     9781 ccaggctcaa aggccagttg cccaaatagg gctgcctgct gatcacctgc catgccagca
     9841 atagctacct ctcctccgta aaaatgaaaa gaagccgttt taccataaat ttccgaatta
     9901 gacctgacct caggaagcat ggccttaggg atattcagca aggccaatat ctcatcgtcc
     9961 cattttagct ctttgatatt gtatagcatg gtacgtgctg cattagaata atccgtcaca
    10021 tgtaccgccc cgtccgttag cttccaaacc agccaggtgt caatcgtgcc aaataataat
    10081 tctccccttt cagctcgctc ttgagccccc ggaacatgat caagaagcca tctgagcttg
    10141 gtcgcagaaa aataagcatc tataaccaag cctgtttttt catggatcat tttggtatag
    10201 ccatcacgct ttagctgctc tgcaatggag gctgtttgtc tagattgcca cacaatagca
    10261 ttatagatgg gcagacctgt ctgtttgtcc cagactaccg ttgtttcacg ctggttggta
    10321 atgcctatag cttctatttg ctctggcttt ataccagact cgataaaggc gtctgcaata
    10381 acagactgca ccaaattcca aatgtgattg gcgttgtgct caacccagcc agcctgtgga
    10441 aaaagctgtg gaaattcctt ttgactacta accagcgctt ctcctttctt attgaaaata
    10501 atggcacgag agctcgttgt gccctgatca atagccataa tataggtttc agttcccatg
    10561 tgtcctccat tctatcgctg ctgagatagg ctctctcaat catagcaagc gctttctact
    10621 ctattataca acatttacag cccatagcct atccttctag tcataaaagt atcactctgc
    10681 caaatcctaa gctgataatg cctatcattt caactaaaca gcccttatca cagccaaata
    10741 ccagcaacaa aggcgggcta taggctagcg cctaaatggc tgccaacaag ctccagctct
    10801 atcaggcaca acaaggaaca acaaaaaacc taagcccttt tagcatataa aggcttagga
    10861 atgttacagg cttttatcac ataagcggtg atagcttttt aatcgtaaac aggctcagag
    10921 gacttttcta aaatatctcc actattagca tcaatagtat agctgtactc ctgatccttg
    10981 gcgtcaaact caatatcgta gaccacccta ccgtcgtctg tttctttcgt cagctttagc
    11041 ctttgggcgt cagctgctgt gattgaggcg tccttaaaag caagctcctt ggccttgtcc
    11101 tctgaaatgc cagctgcttg atcagcctga ccaccagctg cttgagctga agcaggagcc
    11161 tcagtgattg gctcagagga tttttctagg atctcaccgg tattagcgtc aatggtatag
    11221 ctatactcct gatccttagc atcaaactca atatcataga ccactctacc atcgtctgtt
    11281 tctttcgtca gcttgagcct ttgagcgtca gctgctgtga ttgaggcgtc cttaaaggca
    11341 agttccttgg ccttgtcctc tgaaacactt gccttcctat gattctgagc actgccattt
    11401 tgacctagag cctgattctg ttgacgacaa gctgataggc tgattaagga tagactcgta
    11461 agagctatta ctgaaagttt tttgattatc attgtattga ccttccgtct ttattcatct
    11521 tatttcctct agtatacatt aaataatctg attttacaat tttaaagcgc taaaactctc
    11581 ttaaccaggc ttactccctt atatgataac ccccaaagag cccataaggt aaaggtaagg
    11641 actttgctat ccctcaacca agaatagatc acccagccga ataaaaaaag caattattgg
    11701 tagaatgaga agaattattt tggtcttatt tattgccttc accagctatc aatcactatt
    11761 taatgaccat tttggtatga accctcactg ccactcacta tctgacacca agctactttt
    11821 aagtaccagc atcgatgttt cttacacctc cagtgcgtat ccatagccga ccttcagcat
    11881 ttaccagcat ttctgattga ttacaaatac tccctaaact gttgaaaaag tatctaaacg
    11941 aaccatacaa aacttaattt accttttttc tatataaata gctaaaaaac atagtaaggt
    12001 cacaagggat ataagattta cattgcttat agtagtcgat aagaaataaa aaattaaaaa
    12061 aataaagtaa gaagcccctt ctttgcccct cttagcactg tcaaccagta tatagataaa
    12121 aattaaagca taaagacctg aaaaagtaat caataacatc taatttacct tatatgccaa
    12181 gcatgctcct aaagcagtaa agccgtctat acatactcct tttagcaccg gatgaggtat
    12241 tttgcaaaat gtaattcctg tcttgagacc tcctaatccc ccgataacag cattacctgc
    12301 tgcatttcct cctgaaatat cttgcatttc acttattgct aatgctctat aatgttccat
    12361 ttctattatc ctcctaaaac aaggttccaa actcagaatc tttctgtttt tctcatttct
    12421 aaaagcctcc tgtgacacca atagatccac aagctactcc acatactgga aatccaagtg
    12481 ctgcgcctgc acttcctgct ccaatcacac ctgacacatt ggcagcccaa ttattttttc
    12541 ctccttcaaa gctagcaagc atttctgtag ccattacgtc aaattattgt attgattgca
    12601 aatactccct aaaaatcgat gttgtccagt tgcaaccttg acatatttag tataacgctt
    12661 tttttgtaaa acattcctcc atatcctaaa cagtcgttga aacgtcctaa atgggagcat
    12721 ttttttcgtt taagactgca aagtgaccat taagggaagg cgtgaagcga caagcctgtg
    12781 gctttaggaa ccttaaaaac attaaaagca agcttctcat tgctattaac aacacaaaaa
    12841 aagcaccagt ctggtcctca ctaggtacta gttatcagtc acccccctaa agttgacaag
    12901 aagccaaaaa aagagaactg actagctctc ttagtgtgca gacaaatcta tctgcttaca
    12961 ttaatgacaa ttctcagaag tgcaaaagac agctattagc ccttacttga gtacctctcc
    13021 tttgcttggc ctactagaga ttctctcaat caggcgacta gtccggatta aaagccagtc
    13081 tagccaagcc catgaaattg ctgatagagc tcttggcgat tcaccttata gtctttggcg
    13141 attgtcttga tcgcctgatt aggcttcatg ccagcagcaa tagcctgttg aacaagtgct
    13201 agcagatcca aatcctcagc aggctctgat gcgtcagctt gattggcacc tgccacaatc
    13261 aatagacact cacccttgag tggatggtct gctagatagg tcaagacctc tgaaatctga
    13321 ccacgctggt attcctcaaa aagcttggtt aactctctca ccagcaccac ctggcgatcc
    13381 ccatagcagg ccagcaggtt tgttagcgta tccttaacac gataaggaga ttcataaaag
    13441 atttgagtct ctggataatc tgccttagtc atcaaaaatg ccctttgctg cccagctttt
    13501 cttggcaaaa agccataaaa cagatggggc tggggcgcca agccactagc aatgaggccg
    13561 gtaatgcccg cagaagcacc cggcaaagca acaacagtaa tatctcgatc aatagctgct
    13621 ctgactagct catgaccagg atctgaaata gagggcatac cagcatcgga gacctgagcc
    13681 aatgaccttc cagccaacaa caggtccagc aaatctggaa ttttatcata agcattatgc
    13741 tcatgaaagc ttacctgctt tgtctttatc ccaaaatgct tgagcaacag accagtattt
    13801 ctcgtatcct ctgcacagat aatatccacc tcttttagaa cattgaccgc tctaaaggtc
    13861 atatcctcta ggttaccaat aggggtaggc accagataga gaacccctga ctctttttct
    13921 tccttgaagc tcttttggat ttgcatgact ctactttcta tctaatagct ctcgacaaaa
    13981 catacactct tcatcatttt cacgacgttg cccatagaaa aaattgcaga tatgaaagcc
    14041 ctcatcataa atgccctcca agtggtcctt gccctgctta gaagaggtct tggccagatt
    14101 ttcgtgctcc aattgactca agcgctcacg taatttggtg ttttcaagcc taaggatagt
    14161 attttcctct acgagtcctt ggacctgctt tttcattgct tcaatttcag ctaaagtcac
    14221 catcaggttt tgtgaaaagc catcaaaagc gtcaaacagt tcttttttat tcactaactt
    14281 taacctcctc taaagcatag gttaccaagg ccagctggtc cttaaagcga acctgaatgg
    14341 tatctgtaaa aagatcaatt cctgcaacct cacctggtcc ctgcgctgtt cttactatag
    14401 taccataatc aggaaatttt ttcttacttt cttgataaaa atcgtcctca tattgtaggc
    14461 agcacagcaa gcgaccgcag cagcccaaag actttgccga atgcaaggac agcccttgat
    14521 gttttagcat tttgattgag actggaggaa actctcctaa aaagcttgaa cagcatagtg
    14581 ggcgaccaca gggacccagc cctccataaa cccttgcctc ctcacgacta ttaatctgac
    14641 gcagctcaat ccttgtcttg aaataggcag ccaaatcctt gaggagctgg cgaaaatcaa
    14701 cacgctcctg agcggtaaag gtaatcaaaa cataacgtct ctcaagggag aaaacaatgt
    14761 caaccaaggt catgtctaag ccatttctgt caatcatctc tgctactttt tgctttgact
    14821 gggctgctag ctgaaggttt tgctggtaag ccttgtagtc catgtcattg gcaggtctca
    14881 aaacagaggg catatccttt ggcaggtcgt ccttacaaaa gctttttatc ggagaattga
    14941 ccactgccaa tcgactgccc ttgccatcag atatgacaag cttggtttgc acaggaaagg
    15001 cctgatcggt ttgaacgtac ctgacagagc aggtgtcaca atatttaatt ccaatcgtac
    15061 ttatcatgaa atcaccatat attctaacgt attttgaaag ctgacattgc tttgccacat
    15121 aagtctagcc tgataaacag cctccagata ggtaaaagca ttttgtcgac tgtagtcctt
    15181 cgccaagatt aaggttaaaa gagttagtgc catgtcctgc tcctcttttt cctctgctag
    15241 ctgaaccaag cgattaagct ccagataagc ctgttcctta tcctgaaacc agatggaaac
    15301 aaaacgctca gcctgcgcca tcagctccaa cagcctggtg ttttcagaaa aagcggtaag
    15361 ctgctgggca ttggctgcta atctggctaa gaggtctgct tgatgtttca aaagcccctt
    15421 tttttgggcc agctcagaga ggtagtgctc atcttttgga aagtgaaaaa cctgtgtacg
    15481 gctcttgatc gttggtagga cctgattgtc atcattcgtt agtaaaaaca tatagcaatc
    15541 cccttgtggc tcttctatat attttaaaat gctgttagct gcattgacat gcatcttatc
    15601 acaatcctta atgataaaaa cctgccgcct gccctcatag ccggtctgcg aaaaatttgt
    15661 catcatttct ttgacggtat cagtcttgat aagctgaccg acaggctcta agatggtgac
    15721 atctgaaaag tcattgtgct caatcagctg gcaagcacga cagtgatgac aaggagcatt
    15781 gcctcttttt tgttcgcaaa aaagagtctt ggctaaaaaa agagccatgt caaaattggc
    15841 aaaatcacct gaaaagaggt aggcatgatt tagacgtttt ttttgcaaaa tctcttgaaa
    15901 ggcctgatag accctaggag ccttttgagc caaatccatt cctaacctcc tgctatgctt
    15961 gactgtgtgt gataatggca gctaaagccg ctgacacaac gctttctaag tcctgtgatg
    16021 catcaatctt gacaatacgc tggggatttt ccaaagccag ctccagatag cccttacgaa
    16081 cacgctggtg caaatctaat tgctcaagat caagacgatt gatctctcgc tcagtatttt
    16141 gtgcaatcct tgccaatcca agctctgagg gcacatcaaa atacagggtt aaatcagggt
    16201 caacaccatc tgttgcaaaa tgattgagcc attgaatggc ttgcttatcc agccctcttc
    16261 cggcgccttg ataagcaact gaactgtcaa taaaacgatc caccaaaacc aagtgtcctg
    16321 actcaagagc tggcatgatc ttttcaacca aatgctgcct tcttgctgca atatagagca
    16381 gcagctctgt tttatcgtcc atggtcgtgt gactgacatc taagatcagc tgacgaatct
    16441 tctcagcaat cgcaacgcct ccaggctctc tcgttgttac aatggtttgt cctagagctg
    16501 cctgtaagag tggcaccagt ctttccagca ccgttgtttt tcctgctccg tctggacctt
    16561 caaacgttat taattttcct ctagtcatct ttattccttt gtttatcgtt acctctattt
    16621 taccaaaatt tgcctgaaaa agcactgcca attcattggg cagtgccaga tcagaaaaaa
    16681 gcctttttgt gctgcctttt aggcgatagg aataaaaagc cagccctcaa agcagcagcc
    16741 taagacttgt gcctcacacc tcaaagccta tgagcagcca ctcgataaat gacaatcgtc
    16801 tcagctctta ttttctttgc ctaagcaagc cagcagggct gatccatcag ctttgagcaa
    16861 ttgatgagct aagacatgct atataagaca ggatcaggcc tacttagccc tgctcaggta
    16921 gggcttgagg ctctagaggc tcacgatgta aattcccaac aaaatcacaa tcaatgtcat
    16981 caaaggctga taccttcacc tctttgacaa atgttagccg actaatgtcc tttagctttt
    17041 cttccatgtc ctctttattg atgtaaataa caaggtatcg agaacgcctg gaatggtagt
    17101 acaagtcacc atatttcatc acttttctag cgtctcgatt gtaatacagg tagataacca
    17161 gcccaattct ctgctgtttt tgaaacattt aggtactctt ttcttttata ttttgatacg
    17221 gtccaagctc atgtcgaggt ctatttgtcg ccaagggaag tcctgtgtcg acaagaatat
    17281 cctcagacac tgcttctgca atagctgtcg aaatcgtcgc caaaacctcc tgcaaatcaa
    17341 cctgtgccaa gcgcagatca gcaaccaatg gatgcaggtc aagctggcgc ttttgatgaa
    17401 gtaattggca gcgcaacgct ctagcatctg gacacaactt aagcaagtcc tgcctaagct
    17461 cataatcctg cttaagctcc tcaaataagg ctaactcggt ctgtagggcc aaatctgcct
    17521 caaaagcctt tttagccaag gcataggcct gatactggct gcttgtccta atatcctgaa
    17581 ccagctgctc aatagccttt tcaatggcaa acaattcttc atttatgatt agcataggtt
    17641 aattatacca taattttaag gaagatagcc ctctttagca tgcaaaaagc ccctgaaaca
    17701 atttgtttca gaagctgtta agctatttta ctaagctctc taagctagct cattattttc
    17761 catgatttca tcaataaagc cataggctag ggtttcttct gcgctcatcc aataatcacg
    17821 ctcagcgtcc ttatggattt gtttgatcgt tttaccggca ttttgtgcca aaatcttttc
    17881 caggcggtga cgtgtcttta ataaatgctc agcagcaatg gccatatccg tctgctgcgt
    17941 accacctcct gtgcctccca taggctggtg aatcatatat tctgcatttg gaagcataaa
    18001 gcgcttgccc tttgcacctg atgaagcaat aacggttccc atagaagcag ccatacccat
    18061 aacaatggtt tgcacatctg ccttaataaa gttcatcgta tcaacaatag ctaaaccagc
    18121 tgatacagag cctcctgggg tattcacata gaggtaaata tcttttgtgt tgtcttgggc
    18181 atctaaaaac aagagctgcg caataacaga gtttgccata ttatcctcta ctggaccagt
    18241 cagcatgata atacggtcct ttaacagacg tgaataaatg tcataagaac gctctccacg
    18301 actggtttgt tcaataacta caggaatcat aaaaatctcc aatctatcgt gactgtctaa
    18361 caccactctg cctcatgcag tgacaggcag tcaaacacat ctttttataa tgattgacct
    18421 tattataatc tcttggtcaa aaaaggtcaa atgataaact tgcttttaaa aaccttccag
    18481 cctaaactag aaagtcttat tagctttagc aggctagcct ctagcaagca gagcctagca
    18541 caaccaaagc ctgtagcctt ttacttggta ccaaataagc gatcaccagc atctccaaga
    18601 ccaggaacaa tgtagccatg atcatttaat ctttcatcaa gggctgcggt ataaatgtca
    18661 acatctgggt gagcctcctg aagcttttta accccttctg gtgctgctac cagacacaca
    18721 aacttaatat tagcagcccc acgctttttc agtgaatcca ctgcaagaat agcagagccg
    18781 ccagtagcca gcatcggatc aacaataaaa atttggcgct gatcaatatc ctctggcagc
    18841 ttcaccaaat attcaaccgg ctccaaggtc tcctcgttac gatacatacc gatgtgacca
    18901 accttggcag ctggcacaag actaagaaag ccatccacca taccaatacc agctctaaga
    18961 atcggaacaa ttgctaattt tttacctgct aactgctttt gaaccgtctt ggcaaccggt
    19021 gtttgaatct caacatcctc taatggcaag tcacgagaaa cctcgtagcc cataagcatt
    19081 gcaatttcat tgaccagctc tctaaaatcc ttggttgagg tatcctgacg acgcaggatt
    19141 gatagcttat gctgaataag tggatgcgaa ataacctgac attttcccat gatgacgtac
    19201 ttccttcttt attttttaca cttttgctat tataccaaaa aattgaaaac cttgcttact
    19261 tttttcagat ccggttgaaa tgataaaagc aagaatctga tcagctagct gcctgcttca
    19321 gctgccttga tcttgggtgt caaagtccca atttttggcg atacctagct gctctgctgc
    19381 caattaattt gtccagctga cgcgtcaata acgtcatgta ggcgtaaaca cccattccca
    19441 agccaccaat aatcactaag taaagcaggc tagtcaatct gcctgtcggc ttaaacaaat
    19501 agcccaaaaa ccagttagct agtagcacaa tcaggcccat caatgctgtc tcaatcaccg
    19561 ttagtaatat acgcttatgc agcagcttac ggttaaatcg tgtgacctga tgtagacgac
    19621 ggtacatgag atagataggc actagcaagc caagggtcgt agctaacaaa ggaccataag
    19681 catgaaacag atagatcaaa ggaacctgca aaaccagctt gacaaaaaca ccataagcaa
    19741 aataatagat ggccttacgg ttttcaaaca gggcctgcag catcggagaa aaaagcgtat
    19801 acaaggccat caatagggta aggcaaagca cagcaacaaa cagcctaaca gcctgtccct
    19861 cgctactacc gtaaaaaacc gtataaagag gccttgccag tataatagct cctgtcagag
    19921 caggcaataa aaacatcagc agcatttcaa tgttgttaat gatcaggcgc cctgctgctc
    19981 gcatgtcctt tttaatgtaa ttttctgtca ataaggcaat accaacacta ccaattgaag
    20041 cggctactgc aatgagcacc atggtgattt tagcagggtt ggcgttaaaa tacccaaaca
    20101 gcacccagag ctgagaacgc gtgtagctgg taaacagagt catcgtattg acaaaggtcc
    20161 actgatcaag gagctgaaag gcctgaatcg cacttcctgt aataataaag ggaatcgact
    20221 cctttaacgt ttcaataagc aagcccttga tgtcaatagg aatcgcatgc tctgtcttgg
    20281 taaaaatagc ctttaaaagg ccctgcgtcc agaaataata aaagagcacc gccatactgg
    20341 ctatcattcc aataaaagca gcaaaggtgg actgcgtaac agctgcaata tagtccttag
    20401 accccatttt catgatgaaa aaggttgtta gaagcatcca gatcacacga accagctgct
    20461 cagcaatttg gctaagagca tagggcttaa tctccttata gccctgaaaa atccccctaa
    20521 tcacgctcat cactggaaaa acaaaaacag ctaatgataa gctatgcata atcgggacaa
    20581 gggtctcatc accaccggac aagcgagcaa agagcggaga tcccagatac atcagcactg
    20641 agaaaatcaa gcctaatacc agcataacct ttagagtgct tcgaatgagc tgatagctat
    20701 gctcttgctg tcccatcgag ttgtacttag cgacctgctt agcaatggca acatttagcc
    20761 ctgttgtcga aatcaacaaa aaataggcat acacattgta tcccatatta aagagcgcat
    20821 ttgcctgtat cgcatactgc cccatccata tgtaccatgg aataatatat agaacgccta
    20881 aaagtcggct aataaaatta cctgcggtgg accaggctgc tccctgaacc atcagctgtt
    20941 cttgtgtcaa ttgttttttt tctgtcgaca tatccgttct tcctagtttt tatagcttta
    21001 ttataaactt ttgcttgtga cttgtaaaac aagaacatta aggataaaat aaggctatga
    21061 taacaattga gcacttatta accattttaa aaaaggacca taatttccga gaggttcttg
    21121 atcaagacgg ctaccacttt aactatagcg gtctacagtt tgacagcctt agctacgaca
    21181 gcagacaagc agatgagcag acgctctttt ttgctaaggg atcagctttt aaggctgact
    21241 ttttgagaca ggccattgcc aagggactaa gactctatgt ttcagagatt gactatcagg
    21301 tagggatccc tgttattctt gttaacaata ttaagcacgc tatgagccta gctgcgatgg
    21361 ccttttatga ttacccacaa aataagctca agctattagc cttcaccgga acaaagggca
    21421 agacaactgc tgcctacttt gcctatcata tgctaaagga atctcataag cctgccctgc
    21481 tctctacaat gaacacgacc ttagatggcc aacacttttt taaatcgcag ttaaccacac
    21541 ctgaaagtct tgatttattt gcgatgatgg ctcagtgtgt ggctaatggc atgacgcatt
    21601 tggtgatgga ggtctctagt caagcctact tggtcgggcg tatctacggc ttaacctttg
    21661 atgtcggtgt ctttcttaat attagccccg atcacatcgg accaatcgag cacccaagct
    21721 ttgaggatta tttttaccat aagcggctct taatggaaaa tagccgagct gttgtggtca
    21781 atagcggtat ggagcatttt aatatcctag cagagcaggt ggctgataag cctcatgatt
    21841 tttatggcaa aggggcttgc aataggctgc tgcagcggca ggccttctca tttcaagcag
    21901 ccggcaaggt agctggagac tatgcgattc aattaattgg cagcttcaat caagaaaatg
    21961 ctatggctgc tggactagcc tgtcttcgac tgggggcaag cctagaggat atccgccaag
    22021 gcattgctaa gacaaacgtc cctggccgca tggaggtctt aaccatgacc aatcaggcca
    22081 aggtatttgt tgattatgca cataacggtg atagccttga aaagctccta tctgttgtcg
    22141 aagagtacca gaaaggccag atttacttga ttctaggagc accgggcaat aaaggcgaga
    22201 gccgtcgggc tgattttggg caagtcatca accagcaccc caatgttcgt attattctga
    22261 ctgctgatga tcctaatttt gaggacccac agctgatttc agaggagatt gctagctata
    22321 ttcaccgcga ggttgatatt atcattgacc gtaaagaagc aatcaagact ggtatggagc
    22381 gctgtcagaa tgagcaggat gcactcatta ttgctggcaa gggggctgat gcttatcaga
    22441 ttgtcaaggg acaaaagact gcctatgcag gtgatttagc gattgcaaag agctacctat
    22501 agactggtct aacaggctaa acagtaataa ttcttaagat tactgataat gattctaagc
    22561 tggctccttt tttagcataa actcagtaat tagattctga aaggcttttt taggcctttt
    22621 ttctatgcta taatgggata gcttttaaga gaaagcgcac tattatagtc agaccaaaaa
    22681 agcgactagc atttcatagg ctatcagccc cttagaattt tgctagctgg ctttgcttga
    22741 ctattagaaa ggagaaaaac catgtcaaca atcagtgctg agaggatttc agctggctat
    22801 gatcaatcgc ttatcatcag caacttatct gtcactattc ccgaaggaaa ggtaacaacc
    22861 atcatcggtg ctaatggctg tgggaagtca acccttttaa agactctggc acgactattg
    22921 ccactcaaag cagggcaggt tctcttagat ggacaagcca ttgctagact agcaaccaag
    22981 gacgttgcca gaacactagc agttttacct cagctgcaag aagctactac agctactgtc
    23041 tatgagctgg tttcttatgg gcgttatccc caccaatcct acctaggaca actcagtcaa
    23101 gctgataagg ataagatttg ctgggcaatg gaggtcacaa gcatggcacc ctatgctcat
    23161 caggctgttg atgccctgtc aggcggccaa cgtcaaaggg cctggattgc tatggcctta
    23221 gcacaggata ctgatattat ttttctagat gagccaacaa cctacttaga tatgaatcat
    23281 cagctcgata ttttagaatt actaaaggag ctcaatcagg tctctggaaa aacaatcgtg
    23341 atggtccttc atgatttaaa tctttcagca cgctactcgg atcatctgat cgccatgaaa
    23401 aatggacata tcaaatattc tggagaggtc aaccaggtga tgacgccaga gatgattcaa
    23461 gacatttttc aagtaaaggc tcagctcgtc actgatcctc tctatcattg ccctacattg
    23521 ctgacctatc agctgatata aatttattct aggagaatag aatacatgaa aaaactactg
    23581 cttattttaa ctgtttttgt gacagctttt acattagtcg cctgctcaag tcaaagcaag
    23641 caacaagaaa gcaccagcaa agcaagccta tcccacaagc caaaaattgc tggagtgacc
    23701 tattatggtg acattcctgt caagccaaag cgcgtggtta gcttagcagc tacatatact
    23761 ggttacttgg caaaattaga ccttcatctg gtcggtgtca cctcctacga caaaaagaac
    23821 cctgttttaa caaaaagcat tactcaagcc aagcaggtgg cagctactga cctagaggct
    23881 attacagcac tagagcctga tctcattgtt gttggctcaa cagaagaaaa cattgaccag
    23941 ctagcaaaaa tcgcaccact aatctccatt gaataccgca agcgtgatta tttgcaggtg
    24001 ttttctgatt ttggccgtat ttttaacaag gaaaaggaaa ctgaccaatg gttggccgac
    24061 tggaaacaaa aaacaagtga ctatgaaaaa gaaataaaac aagtcaccgg atcagctgct
    24121 acctttacaa tcatggggct ctatgaaaag gaaatttacc tttttggtaa ggactgggga
    24181 agaggtggtg aaattattca tcaggcctta cattatgatg ctcccgaaaa ggtgaaaaaa
    24241 gaggtgttta agcagggcta tctgtcctta tcacaggagg ttctaccaga ttatattggt
    24301 gattatgtga ttgttgctgc tgaggatgac caaaccggct cagccttata tgagagcgac
    24361 ctttggcagc agatccctgc tgtgaccaac aatcatgtca tcaaggtcaa cgctaatgtc
    24421 ttttacttca cagacccact gtcactggag caccagcttg aggttctaaa aaaggctatc
    24481 ctctcaactg gtgcaagtca ataaaaactt aagatgacag ctcaacatca tactaagcct
    24541 aaactagcta aagcagctcc tccttggctg atcttaacct ttatcagctt aactctagtg
    24601 cttgccattt actgcagtct gaggtttggg gctgtgtcac tatcacatca ggagctctat
    24661 catattctac ttggaaagca ggaccagggt caaaaggcca gcattatttt ggacattcgc
    24721 ctgccccgct tgattttagc agctctagtt ggtgctgcac ttgctgtttc aggagctatc
    24781 atgcaaggca ttaccagaaa tcccattgcc gagcctggct tactgggaat caactctgga
    24841 gctgggctgg cattagtcat cggctatgct ttttcccctc atcttcatta ttcgacaatt
    24901 atattacttt ccttgctagg gtcactctta gcgaccctat taattctcag cctagcctat
    24961 caagctggta agggctacac tcaaatgagg cttattttag caggagcgat gatatctatg
    25021 ctactgtcag ctatcggaca aggaataaca acttattgtc acctagccaa tgccattatt
    25081 ggctggcagg cgggaggatt gatcggggtc aattggcaga tggttagcta tgttgcgcca
    25141 ctcatcatct gtggcttagc cctatcttat ctgctagcct atcatttgac cattttaagc
    25201 ttaagtcaag agcaggccaa ggccctaggg caacgcacct tcttgattag ccttatcttt
    25261 attggacttg tgctgcttct gtcttctgct gctgtagcag tagccggcag catttccttt
    25321 gtcggcttga ttatccctca tgccatcaca ttagtcactg ctaaggatta ccgctggatc
    25381 ctgccgctag ctactcttct tggagccagc tttatgcttt gggtagactt tgcctgtcgg
    25441 aatatcaatc ccccctatga aacaccacta tctgctttga tcagctttat tgggctgccc
    25501 tgctttttat ggctagttag aaaaggaggt cgcttttgac agctactaaa agacacgtcc
    25561 cattatttct aggactaatc tctggactgg tctgtttgat gattatttcc ttgtctattg
    25621 gggaatctag catgtcacca ttggaggtcg tcagggtgct ttttggtaaa tccactgctg
    25681 atatggcctt gatcatcacc aacattagac tcccaagaat tttagctgcc tgtatcggtg
    25741 gcggctcact ggccctttct ggcttaatgc tgcaaagctt aacgcgaaat catctggcag
    25801 attctggcat actaggcatt aatgctggtg ctggtatggc tattaccctt gtcatatcct
    25861 acagcactag taacagtctg accagcaggc aagggctgcc gcttatgacc atatccgggg
    25921 caatggcaac cattgtcttg gtctacctgc tctcacttcg tcatggccat attgatccta
    25981 ttcggctgat tgtcactggc gtagggctat caaccatgct atctagcctg atgattgcct
    26041 ttgtcggcaa tgtgaaccgt tataaggtgg attatgtgat tcattggcta agcgggcagc
    26101 taacaggcga tgattggtcc aagctaagca ttgttgctcc cttattgggg atcacttggc
    26161 tgctagcctt tagtcaagcc tataagctca acatcatggc attaaatgat gaagcaagca
    26221 tggctctagg cttcaagctc catcagtacc gtaccattgt tcttgcacta tctgcgattc
    26281 tctcagccct aagtgttatt ttggtcggaa acatcacctt tattggtctg atagcaggcc
    26341 ataccagcaa acgactagtg ggagctgatc accgattaag cctgcctgtc agccttttca
    26401 tcggcatgat tctgcttctc ttggctgaca ctatcggacg agtctatctc gtcggcagca
    26461 atataccaac cggtattctt gtctcaatta ttggtgcatc ctattttctc tatctgatgg
    26521 tcaaaatgac ataagagcct ctgctgcata gcttaaaggg ctcagcaagc ataaatggct
    26581 tagactcaac tgttttacag tgtgggtcta agccattttt tattcatcaa gtcaactctt
    26641 aatcagcgta gaaaatcagc tgctccttat caaaagccag cttcaggcag tatttagtgg
    26701 cctctacttt ttcaatatag cctagaagct ccaaggcatt cacaaaaata tctgtccgct
    26761 tttgcataac aatctctttt ctagcaaatt ttagaagaaa gctggtcatg tacttcaagg
    26821 catagtcctg attcacatca cctaataggg catagagcct taattgctca tcagataggg
    26881 cttcccctct tcttaagcgg taaaaataat tggcaagcgt cagcttatct cggtcaatgg
    26941 ttgttttttc cttgatcaaa acctgattgg tctgattaga cagcactgtc tcaaacacca
    27001 aggccatcaa agcttcatat agatctgatg ccctatccac aaagattaga tcttctaatg
    27061 tcacctgctg caggtcatct agcaagggca gacacagata gtagcgtctg ttttttcgac
    27121 agatatagcc agcctgaatg taagcttcaa gcgccttatc aatcccctta acatgagaaa
    27181 aggcctgctt aatgtgacgc agggttacgt catcatgctg attgaggtaa tgaataaggt
    27241 cttgaaaaaa aggctgacgc gttaatttat cagggttaaa aatggtaatc atactactat
    27301 tatagcaaaa agaccaaagg gctgctgata aaaatcaaca cccctctaca ggcaagctct
    27361 atgctccaaa gctttcagtt aattgaggga caacctgctt tttacgagat acagcacctg
    27421 ctaggaaagc atgattatcc tcaagcttaa agctaaaggc tgcctcaacc ttatccatat
    27481 tcgcaccaag cgccaaaatc tctgaatttg aattaacaat atctgtaatc atcaagacaa
    27541 aatcagaata gccctcactt gccatcacct ctctaatagc ggcctcaata gcctccttgc
    27601 gctctaacac ctctgcaatg tcaacggtat tgacctgggc tacacgaact gcgttgccat
    27661 ttaattcaaa ggtcttagca tcaatatcaa tcaattctgc ttctgattta cttgcaaggt
    27721 ttgttccggc ctttagcata gccataccgt attcctctag cttaactcct gctaactctg
    27781 ctaattccgc agcaacacga tgatctgaag catgcgttgt tggtgatttt aacagcaagg
    27841 tatcagaaat caagccagac aaaagcatgc ctgcaatgtc ctttggcaca tcaaccctat
    27901 tttccttgaa caggcggtaa acaatagatg aggcagagcc aacaggttcg acacgcatat
    27961 aaagcggatt tgctgtctca aaattagcca cccgatggtg gtcaacaata ccatacacct
    28021 caacctcacg aatatccgaa atagactgtg gaaattcgtt atggtctgtt agaataacat
    28081 gactagcacc ctctgctttt gctgatgtca ccactcttgg tgctgatacc ccaaaatagt
    28141 caagggcaaa ggctgtttct tcatttgggt cacccagagc gactacctcc gtatccaaat
    28201 caaaggcttt ttttgctaag tagtcaaaag catacgatga tgcgatggca tcagtatctg
    28261 gattttgatg accaaaaact aatagttttg acataaagtt tctacctcat tctctttatt
    28321 catcttattg tagcagaaat aggctctaaa atcaaagaag attccccagt cacaggccaa
    28381 gagtctaaag ggcataaggg cacagaatct caggtattaa agagtcctgt caaacacaca
    28441 agaacaggca agccagtcca aaaagcaatg ccttctataa tgagctattc agctatttgg
    28501 ggacaataca ctgtccttga ttggtttaat gcttcaagga ttactttttg gcacgtgtct
    28561 gagctcgctt aaaaacactg aaggtctcat caagccagcc gcttcatcag caaaaaaacg
    28621 gctctataat ttccatggtg gatttaccca ctacagaaat tatagagccc atttacctcg
    28681 ctttgcacat cacacaagag aaaacgagct tcgtctcgtg cttagttatc agtcacccac
    28741 tacagttgac atggggccaa aaaaagctgg gcatttccca actctagctt agcctatgat
    28801 tgatgaatac ggttcatgta ttcagtatag gattctgtat gcagcagctt tttggcattc
    28861 tccacccgct ccttggttgg tggcttaacg ccctcaagct ggtatggaat ccctaactcg
    28921 cgccatttga actctcccat cgtatgataa gggagtacct caaacttgtc gacatttctc
    28981 aaggtcttga caaacgcatc taagcgtacc aagtgatcat caatgtctgt caagccaggc
    29041 accaagacat ggcgaatcca gacgggcacc tgcctatcag agaggtagcg agcaaactgc
    29101 aggatatttt tattgggctg acgggtgaca agcttatgct gctcctcgtc aatctccttt
    29161 aagtccagca aaatcaaatc agtaactgct aataatgttt ctaacagctc atggtattca
    29221 ggggttggac gataggcaaa gccacaggta tctagcgttg tatggatacc tagctttttg
    29281 gcctcagtaa agagcgcagt gataaagtcc atttgcagca tagcctcacc acctgacaca
    29341 gtgattccac cctttttccc ccaaaagtgc ctatattgca gagcctcctt taggacatca
    29401 ttaacggttc ggcgttgaga ttgattggtt tccatagccc aggtgtccgg attatggcaa
    29461 tactggcaac gcatcttgca gccctgcaaa aaaatgataa aacgtatccc cggaccatca
    29521 acagaaccaa agctttctgt agaatgcacc attccagtta cttgcccata atctacttca
    29581 accattgtgt ctccttcacc cttgtaaatg gttttacgtt ttcattatat catgtttcat
    29641 caaaaagact aagctcaatg cctagtcttc agtaatattc tgttctatat tagaaatagt
    29701 aagtttcaat ttggtgatac gaccgtcctt tactttgtca ttgaccaaaa ccagatgctt
    29761 ttgcttgcta tcacaggcaa agctctcttt ctccttttga cttggaatgg taccaatccc
    29821 tgtcaaataa aagcccgcga tggtatcgac atcatcactt tctaattctg tgtcaaaata
    29881 ctcgttaaag tcgttgagcg tcattgtccc tgtgacaata taggtgttgt catcaatgtg
    29941 atgaacaaat tgctcagcct tgtctgtctc atcatcaatc tcaccaacga tttcctcaag
    30001 caaatcctca agcgtcacca aacctgcaac ccctccgtac tcatcaagta ggatagccat
    30061 ctggttttga gtatttcgca attgcctcaa caaatcatct acaaaaatcg tttctggtac
    30121 aaagagcggc tcctgcagaa gctttctcat gctgatgttt tcaaagccct gacgaaagcc
    30181 tgattctaaa agccttttgg tatgaattaa gccgatcacc ttgtccttgt caacatcata
    30241 aactggaata cgagagaagc tctgctttag gatttccttg atattgtcta gcgtatcatc
    30301 gttaatgtca atcatgaagg catctgtcct tggaaccatc acctcacgcg ccatcatctc
    30361 atcaagcgag aaaatcccct gcagcatttc aatctcttcg gcatcaagcg ttgcctcgct
    30421 gttagtcagc atgtactcaa tctcatcacg cgtcatgcgc tcatctgcgt catcaaaggt
    30481 cattggggta atccggctca gtaaatttgt cgacgccgat aagagccaaa caaagggact
    30541 aaccaatttc cccaagataa tgatcactgg ggcagaaatc acagcaagct tgtcttttag
    30601 attcatagct atccgcttgg ggtataactc tcccaaaaca atcgagacat aggtcaagaa
    30661 caccaaagaa ataatgctac cagctgtttg agcggtcgca gaaccaccta accagccaga
    30721 aataacctgc cctaaagagg ctgacaggct cgcccctgac aagaggctaa taaaggtaat
    30781 accaacctga atggtcgata aaaagttatt gggctgctct aaaacacgca gcaagcgatc
    30841 atacctctta tccccatcgg cagccttttg ctccacacga gagcgattta aggataccag
    30901 agccatctca ctggctgaga aaaaggcatt taacaaggtt agaatgacta acaataaaaa
    30961 ctgaatcaat aaaggctgac tcacagggtc ttccattaat ataactccta aaacataata
    31021 tactacttca ttatatcaca attgtcgcca aagattgctg atttatttct ttttcctgag
    31081 aaatcacaga cagtctaagc cctgacataa ggctggctga agcttaatca gtagctgcta
    31141 ttttttccag catgattaaa aatggcggct gattcatctg attgatcggc tgatagagca
    31201 ttgctgttac ctggcgctga ttgagctgac caatatagtc caaaagctct tccttctccc
    31261 tactaccgcc atcatgacca taatacacca tgatagcaat ccgtccacct agctcaagcc
    31321 gatcaagtat tttagctagg gctaatatgg tcgtctcagg ccttgtgatc aacgacttat
    31381 ctgcattggg tagatagccc agattaaaaa tggctgcccg aatgggctcc ttaacatatt
    31441 gatccacctg ctcgtgtcca gctaaaataa gctctgcatt agtcaagcct tgctgctcca
    31501 agcgctcttg tgtcttggtc agtgcctgct gctgcacatc aaaagcataa accctttgtg
    31561 acagacttgc taaaaaggca gtgtcatagc catttcccat agtagcatca acagcaatac
    31621 tctgcttatc caaaacttct tttaaaaatt catgtgatac atgaatagga cgctttatca
    31681 tcttatcctc ctaagcaaat acttcaaatg ccgcgatacc atctagtatg tctaagtcaa
    31741 tatgccttcg gccgtaacaa tctagcacat aatctttata ccgatctgtt tttagattga
    31801 attgaagcga ccagatcagc caaaaaagat caatatgtcg atcgcttttt cctgcctccc
    31861 cccaatcaat catggactga aattgccacc gatccaagat catatttggc aaacaaaaat
    31921 ccccatgaat cagagtttca tgctgtaaca agagcttaag ctcctgaatc cgcctgtaag
    31981 cctcctcctg ggactgaaac cgttgctgag gcggtaaaaa gcactgattg aaccgccctt
    32041 ggtgataacc agcctcagca gcttcgatat aggctagcgt tttgtcagct acaggaaaat
    32101 cagacaaaga caggctatgc agctttagca tatgatcaac taagatacga cataagcgct
    32161 tgggatcgga caaatattca atatgactgg cgtcctctcc tgctaccttt gcggttaaaa
    32221 gccaatcctg atcaccgctg atataatcaa gcacctctgt tgctaagccc ttactatgac
    32281 aataccgagt tagggcggcc tccttggcaa gcctaccttt agcggctgtt tttagaaaat
    32341 agccctgccc tttatcaata gcataaacac gtgcctctgc cgagctactg ctatcataaa
    32401 ccaaactgtt ttgtaacagt ttttttaaaa caggtggtag gctcagctcc tctcctgcta
    32461 tcaatctttg tttcattgct tcccccgatt atcccttaag cttacagccc tgccagctat
    32521 ttcttctttc catttctagg tcaatcgcat tcaaaacctc ccatttattc aggctccaca
    32581 tgggaccaat cagcatgtcc ctaggcgcat cacctgtgat gcgatgaata atgatatgct
    32641 caggtatgat ttctagctga tcacagataa tcgatacata gtccttctga ctcaagagct
    32701 gcaagcgtcc ctcatgatag tctctttgca tacgcgtatt ggtcatcagg tgcagcaaat
    32761 gcagcttaat gccttgaata tcattgtctg tgacacagcg tctaacgttt tcgatcatca
    32821 tctcatgggt ttcaccaggc aagccattaa tcaagtgaga cacaatgtta atgttagggt
    32881 actgcctcag acgctgaacc gtttccttat acaagtcata agaatgcgcc cgattaatca
    32941 gctgggaggt ggcttcataa gttgtttgca gcccaagctc cactgtcaca tgcatgcgct
    33001 ctgatagctc agccaaataa gcaatcgtct catctggcaa acaatcaggc cttgttccga
    33061 tattgatacc aacaacgcca ggctcattga ttgcttgctc atagcgctcg cgaataacct
    33121 ctagcttatc atgcgtattg gtaaaatttt gaaaataaac caaatactga ttgacctcag
    33181 gccacttgcg atgcataaaa tcaatttctt tgtaaaattg ttccctgata ggtgcatcag
    33241 gcgccacaat cgcatcacct gagccagaaa cggtacaaaa ggtgcagcca ccatgagcaa
    33301 ctgtcccatc acgattagga cagtcaaagc cagcatcaat gggcaccttg aaaattttag
    33361 caccaaataa acgacgataa tactcattta aggtctgata tctttttgtc atgcctctat
    33421 tgtagcacaa atcccccgat taacagcaga agatctcaat tggctgctac ttctctgatt
    33481 gatgagccaa agcaaggcaa ctaaaaagga ttgaagaaga cctctggaag agacctgcct
    33541 tcaatcacta gcttttctag aactgatctg taacgcgcca tacagctgac tgatcactgg
    33601 atttactttt gctttagctg aaaacgccat tcaaagcgct tttgatcata aaaaggataa
    33661 agcagctgaa gtatgccaaa gcctaaggca tagccagcca acacatcgct aggataatgc
    33721 actcccagat aaatgcgtga caagcctatc agcaaaatca aggccaaaag ggctatatca
    33781 accagccagc gtaaggaggc tgactgcaat ctttgatggc aaataatcag cagacttcca
    33841 ataatcaaaa ggcttcccat cgaatggcca ctcggaaaag aatagccaga agcatgcacc
    33901 aaatgctcaa tgctgggtct tggtctttga tacaagagct ttagcaccca aatcaaaagg
    33961 gccgcaaaaa caccatttga taggacaaat aaggcctcag ctctccagct caaggccaat
    34021 aaagccagca cagcaacaac aacaatcact gcctgtgtac taacatttcc agctacagtg
    34081 atccctttaa aaaactgggt tagcccttca ggcagatgac ctcttagggc taaccgaagc
    34141 tgactatcaa aagacgttag gtcttcggga aaaaatttaa caatatagcc aagcaccaca
    34201 aatagtagca tagcaaagga agacaatagc agatgttgtt gtttatgttt catgatatga
    34261 attcggatat ctctctaaaa ttggtttacc tgcaatatac acgaaataaa agacaattgc
    34321 aaatattagc ccctccaaaa ggttgaaagg aatgaccatt gtaaatatgt agcgagcagt
    34381 accaataaaa gctttaatat caaagccagc aaacttggca tataagggaa tagcaaagac
    34441 atagttcatg acaaccatac caagcgttaa cagccctgtc cccacaagac tagctagtac
    34501 ataggtgacc agccctttct gacgatgcca aatcaaggca aaggcagtga taaaaagcgc
    34561 aactgctata acattcatcg gtataccaat caaatcatta acgccatgat tgtttaaggc
    34621 tagtctaagc aaggtcctca ccgctaaaat caagttagct tgctttagat ccatcaagac
    34681 caagcctaac aaaatcggaa tgatactaaa atcaatcttt aaaaagctgg ctcctggaat
    34741 aatggaaaac cccacaaaca tcaggcaaaa ggatatggct gaaagaatgg caaccatcac
    34801 cagttgatgt gtttttgaca taaaaaattc ctccaatttt gacaaattga aagaagctcc
    34861 ttcgtatgag caggcaaaaa gtcaactcaa aaacccggtc ttctctcttc cagactttac
    34921 tgtcggttgt ggaatcacac cacatcagct tgcgctcgcg gacttctagc tgcactagtc
    34981 accgccggtc gggaattaca ccctgccctg aagacactta tagcatagca aatttaaacc
    35041 tatagcgcaa gacatttttt tgaagcctag cttttccaac aaacacaaga catcaggcaa
    35101 aaaagctaga tgaaagcaac agcaagaaaa atcactttga ggctacaaag ctctctacga
    35161 ggtaggccac cctgtgacat ggcactagcc tagctcaagg caaaaaagag cagactagaa
    35221 gaaacctcca ataacctgct ctggtattac taccgttgtc ccctttacgg tcatagacac
    35281 acctaaccaa tgaaaactcc aatcagagtt ttcagattga agaaaaagtc cattttagac
    35341 ggttttcttc aatctttttc ttttaatcaa aaaaacaaaa gaagtctgaa aaatactgta
    35401 atatcagcat ttcccagagt tttcatgata tgatagtcaa tttctaaatg ttcaattttt
    35461 ctatcgctga tagggtttgc ctacattctg aactccaatc ggagtttttt ctttttggct
    35521 ttagaaaacc tttggcacag ctaatggctc caaactggtg atggtgattc atcagccctc
    35581 tagggcagcg cctttgcttc ttactgctgc tcacaccgca agctctagca gtgtagtgac
    35641 tgtagctggt aggacagtaa gtccttcttg tctcacatca ggctgctata gcccctgttc
    35701 tgtgtcttga tcgc
//
LOCUS       DARYXZ010000022        33281 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYXZ010000022 DARYXZ010000000
VERSION     DARYXZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33281
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            85..366
                     /locus_tag="TV186_000942"
     CDS             85..366
                     /locus_tag="TV186_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL1532347.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            complement(492..917)
                     /locus_tag="TV186_000943"
     CDS             complement(492..917)
                     /locus_tag="TV186_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL1532348.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(914..1318)
                     /locus_tag="TV186_000944"
     CDS             complement(914..1318)
                     /locus_tag="TV186_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL1532349.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            complement(1340..2119)
                     /locus_tag="TV186_000945"
     CDS             complement(1340..2119)
                     /locus_tag="TV186_000945"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL1532350.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            complement(2116..3048)
                     /locus_tag="TV186_000946"
     CDS             complement(2116..3048)
                     /locus_tag="TV186_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL1532351.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            complement(3326..3598)
                     /locus_tag="TV186_000947"
     CDS             complement(3326..3598)
                     /locus_tag="TV186_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL1532352.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            complement(3662..4099)
                     /locus_tag="TV186_000948"
     CDS             complement(3662..4099)
                     /locus_tag="TV186_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL1532353.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            complement(4086..6218)
                     /locus_tag="TV186_000949"
     CDS             complement(4086..6218)
                     /locus_tag="TV186_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL1532354.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            complement(6386..6712)
                     /locus_tag="TV186_000950"
     CDS             complement(6386..6712)
                     /locus_tag="TV186_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532355.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
     gene            complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TV186_000951"
     CDS             complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TV186_000951"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1532356.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TV186_000952"
     CDS             complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TV186_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1532357.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TV186_000953"
     CDS             complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TV186_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1532358.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            complement(9483..10355)
                     /locus_tag="TV186_000954"
     CDS             complement(9483..10355)
                     /locus_tag="TV186_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1532359.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            complement(10514..11839)
                     /locus_tag="TV186_000955"
     CDS             complement(10514..11839)
                     /locus_tag="TV186_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL1532360.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            complement(11823..12545)
                     /locus_tag="TV186_000956"
     CDS             complement(11823..12545)
                     /locus_tag="TV186_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1532361.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            12717..12872
                     /locus_tag="TV186_000957"
     CDS             12717..12872
                     /locus_tag="TV186_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532362.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            12913..13815
                     /locus_tag="TV186_000958"
     CDS             12913..13815
                     /locus_tag="TV186_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL1532363.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            13815..14630
                     /locus_tag="TV186_000959"
     CDS             13815..14630
                     /locus_tag="TV186_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL1532364.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(14815..16236)
                     /locus_tag="TV186_000960"
     CDS             complement(14815..16236)
                     /locus_tag="TV186_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1532365.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(16263..18125)
                     /locus_tag="TV186_000961"
     CDS             complement(16263..18125)
                     /locus_tag="TV186_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1532366.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            complement(18130..18969)
                     /locus_tag="TV186_000962"
     CDS             complement(18130..18969)
                     /locus_tag="TV186_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1532367.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TV186_000963"
     CDS             complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TV186_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL1532368.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            complement(20715..21542)
                     /locus_tag="TV186_000964"
     CDS             complement(20715..21542)
                     /locus_tag="TV186_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1532369.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            complement(21543..22340)
                     /locus_tag="TV186_000965"
     CDS             complement(21543..22340)
                     /locus_tag="TV186_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1532370.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            complement(22858..23367)
                     /locus_tag="TV186_000966"
     CDS             complement(22858..23367)
                     /locus_tag="TV186_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532371.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            complement(23364..23987)
                     /locus_tag="TV186_000967"
     CDS             complement(23364..23987)
                     /locus_tag="TV186_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1532372.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGKVLVDEQDIWKTKERTFFKTIIGYVFQNYSLIENKTVYDNLRLIN
                     KDKKIIADVLEKVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRKIILADEPTGALD
                     SEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDVIIDLKDIGSEI"
     gene            complement(23987..25969)
                     /locus_tag="TV186_000968"
     CDS             complement(23987..25969)
                     /locus_tag="TV186_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1532373.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENNDFILASNII
                     YNSLFSSEAIKKINDLSASLNFSINPVEVYQTVKLNIQSLEHQIFLSKILQIIICGIV
                     FLLIYQYAQMFVALKQNDYVKKIILGLSKTRIAISSLNYFIVTITMVILLTFMLTGQV
                     ELLYIGIASLMVLIFSTIMSFRKLSEKYTQILKGDD"
     gene            complement(26036..26341)
                     /locus_tag="TV186_000969"
     CDS             complement(26036..26341)
                     /locus_tag="TV186_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532374.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            complement(26508..26825)
                     /locus_tag="TV186_000970"
     CDS             complement(26508..26825)
                     /locus_tag="TV186_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532375.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(26807..28096)
                     /locus_tag="TV186_000971"
     CDS             complement(26807..28096)
                     /locus_tag="TV186_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532376.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            complement(28098..28541)
                     /locus_tag="TV186_000972"
     CDS             complement(28098..28541)
                     /locus_tag="TV186_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532377.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            complement(28906..32457)
                     /gene="smc"
                     /locus_tag="TV186_000973"
     CDS             complement(28906..32457)
                     /gene="smc"
                     /locus_tag="TV186_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL1532378.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGVSKVVSVKLKDTQDLTYLS"
     gene            complement(32458..33150)
                     /locus_tag="TV186_000974"
     CDS             complement(32458..33150)
                     /locus_tag="TV186_000974"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL1532379.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
BASE COUNT         9547 a         7789 c         6090 g         9855 t
ORIGIN      
        1 aacgagaagc cttcaaaaaa aaagatgaca accatcagct tttatggtaa aatggttggg
       61 tatcttacgg gaaaggagag gactatgcct acaccattgg agcagcggca gctcaagcag
      121 cagaagcaag agcaggtctc gcagcaaaaa tttcaagagt ttcaagacct caatggacac
      181 agtagcaagc tcaaggaact tatttttttt gcccgtattg ctgtttttag tttaatcact
      241 gtcttgtttg catttgtcct tcttgtcatg aatttggcac cggtttgggc ctttctaatt
      301 gctagtgcta tcagcctagc catcacttcc tttctttcaa aggccatcac gttattaatg
      361 tcataaacag ttagagcttg gcttcgctaa gctctttttt cattactctt attgcctatt
      421 ttcttgaata aacgagtagc ccacatcaca aaaggccctc catagctgag agagccctta
      481 tttttgcctt attattcttc agacttattg ctagctgctt ctttttctga atcatcttca
      541 ggatagttga taataatatc ctcttcatcc agatcaataa tcacatcatc agccttgtca
      601 tgctctgaag cagcttcctt tgcctgatga acaaattggc tggtcttttc cttgataaaa
      661 tcaaacacct gatcagtggt catatcccct gattcaaacc tggtttttaa atcattaaag
      721 gtatggcgag ccagctgact gtactcactt cctttttctt tagccatttg atgatattcc
      781 tcaggatttt gacgataggc ttcataggcc ctttgtgcgc gagccttcaa gacctttcct
      841 ttttcagttg acaagaaata agcggtagct gctcctgaag ctacaccaat caccaacgtt
      901 ttaaaaaaat tactcatgac cttttctcct ttttaccaaa taatttagaa gcgaccttgc
      961 cgacaagagc tactttaccc acctttgcag cattgcttgt ggcatttgtc gcccgacgtc
     1021 caaggtgtct ggcctgcaca ttcaaatcag aaacactttc tgacaaatct gcaatagcaa
     1081 caaagagagg atctattgtt gtcatcttac cattcacatc atctaccagc acattagcct
     1141 tagctaatat ttcattggtt tgataaaggg taacattgac atcactcgtt aaaacggtaa
     1201 tggttttttt agcctcatca actgcctctg acaccttttt taacaccaca atcaaaaaaa
     1261 taaccagagc aacaaaggct aatgcgatta tcagcaatga aatgcccact aaattcataa
     1321 acgtctcctc tttctatccc tattcttgat aataagaaat tcccttttgt cgatgccttt
     1381 taaagataaa aacaatcgca atgataatga gcagcaccga catgtattga gaaacacgaa
     1441 ttcctaaaag catcaggctg tccgttcgca tgccctcaat caccaatcga ccacagccat
     1501 accaaatcag gtaaaatgag ataatatccc catctactaa tgacctgggc ttacgccgcc
     1561 acaccatgat aatgacaaag ccaatcaggt tccacatgga ctcatataaa aaggtgggaa
     1621 cacgatagct gccatctata aacatctgct ggcgaataaa actaggcagg taattgagct
     1681 ggctgacagc cctgccatag gcctcttggt taaagaaatt tccccatctg ccgatggcct
     1741 gagcaagcat gacactaggc gctgcaatat ctaagaaatg gataggattc agcaccttat
     1801 agtagcaata aacaaagaga acaatggtac ctgttatcaa gccgccatag atggcaatcc
     1861 caccattcca aatagcaaag atatcactca aatgctgaga ataataggac cattcaaagg
     1921 ctacataata gattcttgct ccaataattg ccaaaggaaa ggcaatcaga ataaaatcaa
     1981 taatatcatc actggtcatt ttttttcgcg gggcttcttt ggctgccaaa taaaccgcta
     2041 aaagtaatcc caccaagata caaaccgcat accagtgaag actaagagga ccaagcttaa
     2101 aggctattgg attgatcatt tgccctcctc atttttgctg attaaacgtg taaggcgctc
     2161 ctcaaaggtt ttggtagcat caaagcccat ctctttcgca cgatggttca tggcagcagc
     2221 ctcaataacc actgacacat ttcgacctgt tttgacagga atgcgaatcc ttggaatact
     2281 gacaccagaa aaggtaatct cttcattgcc attgcccaag cggtcaaaga ccttgccagc
     2341 ctcaaaattc tccaaataaa tagccaactg cacctgtgag gaatccttga cagcactagc
     2401 accgtacagc gacatgacat caataatgcc aacaccacga atctcaagga gatgacgtaa
     2461 aatctctgct ggctcccccc atagcgtctc ctcatcttta gcaaagacat ctactcggtc
     2521 gtctgccacc aagcgatggc cacgcttgac caactctaag cctgtctcac ttttaccaat
     2581 acctgaatca ccttggatca gcacccccat accgtaaata tccatcagca ccccatgcac
     2641 acttgttcgc tctgctaagg aagcatcaag aaaataagac atctcaccag ctaagcggct
     2701 ggtagatacg cggctgctaa acagagcaat accttcctcc tgcgctgcct gaaccatctc
     2761 ctctgggata gctaggcccc tagatacaat cacagctggc gtgtcttttt taaacatttc
     2821 ctttaagact gagtagcgat tgtgtgaggt catctgagtg aggtaggacc attctttcat
     2881 gccaaacagc tgaagccgct ctggggcata gtaatcaaaa tagccggtca tctcaagacc
     2941 cggacgcgaa atatctgagg tcgttatctc cttttctagc aagtcatcag ttgcatagac
     3001 aacgtcaagc ttgacctttg tgactaacat cttaacggta actgtcataa tttctccttt
     3061 tttaatatta tatcataaat cactatctaa gcccttacaa atacttattt ttcaaagaag
     3121 ctttcaaagt gcttgatcat actaaaaaag aatcctgcaa cagctgcctc aggctcactt
     3181 aaagcaggca ctagcctaaa gcggacaaac aacaaaaggc cctatctcat cagataaagg
     3241 cctacagcca gctttatttc tgataatcac gctagaggca ctattaaaat tcctgtcaag
     3301 cttttaatag tcgctcgctg tggtcttacc aaaaccagcc ttcatcttca tcatttagga
     3361 catcagcatc cttgcgacgt cttggtcctc tcccgtaacg ttcttcaagt aggtcctctt
     3421 tatatggtag gaagatggct aaaagaatat aaataacaac cccaaagcga gtaaaataga
     3481 tcaataaggc ggcaagcaca cgagctaggg gcaaatccca gccgtattta tcagctaaac
     3541 cagagataac tccagccact agcttatgct ttcgttgctt ataaaattta gattccatgt
     3601 ctcctcgcct ccttattcta tgatactagt ttattccttt tttagcaaaa taaaatcagc
     3661 cttacgactg atttttttca atgagcctgc catgacacct gccgcaggca aataccgcca
     3721 gattgatagg acgttttcgg tcataagctt ggccgcaatc ttgacagatg tagaggtaat
     3781 tagcttgatg tgactgtaat tttggagcgt atctcagacc gtctacttgg tctagaagct
     3841 ccttaaaggc ttgatcctta tgccgaaagc ccagcccctc aaaatagagg tgataatgac
     3901 aaagctcatg cctaacgatc tgtctaaaga cagtctcccc atgctcctct aagattttgg
     3961 gattgaaatc cagatgacca tcctttggaa aaaaacgtcc gcctgttgtt cttagtcgtc
     4021 tgttccaaga agcctgatgc ttaaagggct ttccaaaatc agctagcgag acctctctaa
     4081 cataatcagt cagactcacg aggcggcact aagcttaggt tgaccttgtg gcggtctaag
     4141 tcaaccttag aaacccaaac agtgactaaa tctccgacag aaacgacctg acttgggtga
     4201 ttgacaaagg cctcactcat ctctgaaatg tgaatcaaac cgtcctcatg tacaccaata
     4261 tcaacaaaag caccgaagtc aaccacattt ctaacagttc cctctagcct ttgaccaaca
     4321 gccagatcct ttacactcaa aatgtccttt cgaagaacag gagcttcaaa gtcatcacgc
     4381 aagtctcttc ctggcttcag caaatcagca atgatatcct tgagcgtttc ttgaccaagc
     4441 gtcaattgct ctgccatttc ctcaagatta accgcctgta atttggccct tgcaggctca
     4501 tctaagtctt taatcgcaag taattgaaag agctttttga cagccggata ggcttctggg
     4561 tgaacgcctg tattgtctaa tatattctta gcattgggaa tacgcaagaa gcctgctgcc
     4621 tgctcaaagg cctttgcgcc tagtctaggg acctttttga tctcagcacg tgaggtgatc
     4681 tctccatttt cttcacgata cctgacgata ttctcagaaa tggttttatt tagccctgaa
     4741 acatgagcca gtagggctgg actagctgta ttgatgttaa ccccaacctg attaacaacg
     4801 gtatcaacga caaaatccag atgctcagat agctttttct gactaacatc atgctggtat
     4861 tgtccgacac cgattgcttt tgggtcaatt ttgaccagct ctgctagcgg gtcttgcaag
     4921 cgacgcgcaa tagagatggc tgagcgcttt tcaaccgtca gctctggaaa ttcatggcgg
     4981 gctagctctg aggccgaata aaccgaagct ccgctttcat taacaatgac ataagaggtt
     5041 tctggaaaat cctttagcac ctctgcaaca aaggcttcac tctcacgact ggctgtgcca
     5101 ttaccaatgg caataatatc aatctgatag tcagtgatga gctgagctag agctactctt
     5161 gctgcttgaa tcttagcttg attagctggt gccaccggat agataacctg agtagttaac
     5221 agctttccag tcggatcaat caccgctaat ttggcccctg tcctaaaggc cgggtcaaag
     5281 cccagcacca tttttccctt tagtggtgaa attagcaaaa gatgacgcaa attttccgaa
     5341 aagagcttga tagcaccgtc ctcagccatt tcagttaatt ctgtgcggat acgtcgttcc
     5401 atagcaggaa caattttttt cttgattgtt tggttaataa catcatcaat ataagcattg
     5461 tgctccttaa agcgaaggct gaaaaagcgc agcattttgt ctatatgatg ctcaaaggat
     5521 acctttaata cgcctagctt ttccccacga ttgagagcta gggtcctgta gccctgcatg
     5581 ttagataccg tctcagaaaa cgcatagtaa atctgaaaga cctgcttgtc atctaagctg
     5641 gcttccttta ggctagaggt tatacggcta tacttccaaa tctcattata ggtccaggac
     5701 cttagcctgc tatcctctga catggcttcg accaaaatat caacagctcc agcaagggct
     5761 gcctgtggat ccgaaaaacc ttctgtgata aaggcctctg ccttagtttc taggtcttgt
     5821 gcattttgaa ggatcagtct agctagtcca gataagccgg cttctcgagc aatggttgcc
     5881 ttggtacgcc gcttttcctt gtaaggcaaa taaagctcct ctaggtcagc caatttatca
     5941 gctgcttcta tagcttcctt aagggcagct gttagtttcc cttgtccttc gattttagca
     6001 agaatggtgt ctttacgctc cctaagctgt gtgagggact tatccatatc aataatggcc
     6061 ttgatcacca cttcatcaag gttacctgta gcttccttac gatagcgcgc aataaaggga
     6121 atggtattac cctcagcggt aagggtaagc acttgactaa tctgttttgg ggtgaccccc
     6181 aacgcttctg aaatgttttg atgattcata ttttccataa cagttcttat tatagcacaa
     6241 agaaagaggg atagaacaag ataaaagctt tatgacaaat aagtgtcaag aaaacaaaac
     6301 ttatcttttc agatacttct aaaggctaag aaaaaacgat ctccaaacgg aaatcgtctt
     6361 ttagctactt agtggttagt caaaattaag tgagatcttc taactcttcc aactcctttt
     6421 caaacttatt ataaagttca tcaatttcac ttactgattt tgctgcacct accctagctc
     6481 tgaattgtct gttataagac ctaaagccat cctctcctag tttatgctta aatcgtgtta
     6541 acagattaag gatttgcagt cttgaccccc agcgcgctgc actaagcgac ttggtgtcgt
     6601 taatcgtatg ctctataaca tgcccacgag aaaacgcctc tacttttgtt gtgctaactg
     6661 ctactgttgc taaggctagc gctgcagcac tagttaatag taattttttc atgatatgac
     6721 tcctatttgt ttttttatgt agttattata taatattaat aagattatag tttactaata
     6781 tatatatata tatatttcta ataccagtaa cctttgtctg aaaatagcta gatcgtgctt
     6841 atcaaagaaa gcaaaaaagc ttcactctac aggaagtaag agagaagctt ccacgctaat
     6901 aggatactga tctgacatca tcaaaacacc aattgaggag agatttagcc ctcattccaa
     6961 ttgctctttc atcgcctagt ccttttctta tccgaagcgt ccggaaatat aatcctctgt
     7021 acgcttgtcc tttggctttg taaatagttc agctgtatcg ccaaattcac aaatatctcc
     7081 tgtgaggaaa aaggctgttt tatctgacat gcgtgaagcc tgctgcatgt tgtgggtaac
     7141 gatgataatc gtgtaatcct gctttaattg ctgaaccaag tcctcaattt ttaaggtaga
     7201 aatgggatca agagcagagg taggctcgtc catgagcaac acatcaggtg ctacagcaag
     7261 cgctcttgca atgcaaagcc gctgctgctg tccacctgat agggacatgg cactcttttt
     7321 taagctgtct ttgacctcgt cccaaatggc tgctcctctc aaggactgct ctaccagctg
     7381 atctagagtt ttcttgtcct taaggccatg tgtcctagga ccataagcca cattatcata
     7441 aatagacatg gcaaatgggt tgggctgctg aaagaccata ccaacacgct tacgcagact
     7501 gttgaggttt attgctttag catagatgtc ttgattgtct aagagaacct ctccttcgat
     7561 acgacaggaa ggaatcaagt cattcatgcg atttagggtt tttaaaaagg ttgatttgcc
     7621 acagccagag ggacctatca gggctgtgat ctgattttct ggtatgtcaa tggagatatc
     7681 ctttaaggcc tgaaatgctc cataaaagac attaagctgc ttggttgaaa aagctcccat
     7741 tttagacgac tcctttcact aatcggcgtg ataataagct tgatagggca ttgatcagca
     7801 agacagttat gagtaagata acacccgttg cataagcttc cttgacatgt agcccttcgc
     7861 tagacagcat gtacatgtga agagctagtg agcgtcctga tgacatgagg ctggttggcg
     7921 tattggtaga ggtgcctagg gtatacatca gggctgctgt ctcacccaca acacgtccaa
     7981 tcgctaggat taccccggct agaataccag gcattgcagc cggcagcact attttaaaaa
     8041 tcgtccttag cttacctgct cctaagccaa ggctagcctg acgcaagtga tcactaacag
     8101 agaggagcgc ttcttctgtt gatcgaatga taactggcaa caccatgatt acagacgtca
     8161 gaatacctga taaaagagaa tattgcaggc cgaaaaaaac cacaaagaac agcatgccaa
     8221 aaagaccaaa aacaatcgaa ggaatccctg atagcgtatc agctgcaaga cgtattgccc
     8281 ttacccatag tgagtcctgc ttagcgtatt ccacaagata gaagccagca aagacaccaa
     8341 tgggcaaggc tagcactaag gtgcctaaaa ctagactaac agttgagata atcgacggca
     8401 ttagagaaac attgtcagag gtataggtcc atgaaaataa ggataacgac agactaggca
     8461 agccttttat cagcataaag gcaataatca aaaataagga gccaaaggtc aatagcgaca
     8521 aaagatagac cagggctttt agtaaatagt tagtcatgag ctgattttcc tttcacataa
     8581 gcaaagcaag cattaatgat gagaataaag ccaaagagga cagccgatgt tgcaatcaag
     8641 gcctctctat gctgaccaga agcatatgcc atctctagga caatatttgt cgtcatggtt
     8701 cttgtgccct caaataatcc tgatggcagc acaggctggt ttcctgctac caaaataact
     8761 gccatcgtct caccaatggc acgaccaaat cctaaaataa gagcggaaaa aaggccggat
     8821 ttggctgctg gcaggatcac tcgaaaaata ctcctttcat gactggctcc cagtgcaaga
     8881 ctagctgaat aataagcctt tggaacagct ctgatagcag actctgaaag actgataagc
     8941 gttggcaaaa tcatgattcc taagagcaag gaggcagtca gcacactcat gccattacca
     9001 gcaaagctcc taatccaagg cactagcact tgaagaccaa aaaagccata aacgatagac
     9061 ggaatggctg ccatcagatt aacagctgac tttaaaaagc catagcatgc tttaggacaa
     9121 tagtaaacca taaaaactga ggtcaatata cctgttggca caccaatcac cattgcacca
     9181 agtgtgatga caaaagaccc tgcaatcatc ggcaaaatac catagcttgc cggctgattt
     9241 gacggtgacc aatcatttcc tagcaaaaag gctctcatac catacttagc aataaaggga
     9301 aggccattac taaaaataaa gatacagatt aaacaaatag caataattgc catcgctgca
     9361 ctgagaaaga agataacttt aaaaaaatcc tctttaaagg cttgtttatt cactgatgat
     9421 cctttctaag aaaggaaagc aagaacaaaa cacctcttct ttgccttcct tctaatcgtt
     9481 ctttatttga ctttgtccca gcttgttagc ttgccgctaa agacatcagc cagcacatct
     9541 atgccaatat tacttacctt attgtccttg tgaacaatca ctacgatacc atcaagggca
     9601 atcgcatcat caattaagcc cttgctctcc tcagttgtta ggtcacgaga aaccataccg
     9661 atgtctgctg ttttttcctt gacggcggtg atacctgctg atgagccatt tgaggtaata
     9721 tcaatgctaa tggctggatt ttctttcttg tatgcttctg ctaatttttc catcaagggt
     9781 gaaactgagg ttgagcctac aattgacagc ttgcctgata agcccttact gctataggct
     9841 ggcgcgtctg tttttgcttc gatcaatcga ttgtctctaa caatctcctg cccctgcttt
     9901 gagtcaataa aggtgataaa atccttacca actcctgata ggtctgagga ccatacaata
     9961 ttaaagggac gctgcagagg gtatttcccc tctaaaatag tctcacgact agcctttacg
    10021 ccatttacct ttagggctgc aacgtcgcta tttaaggacc ctagcgagat gtagccaatg
    10081 gcacgactat ttcccttaac agaggagatg accccttctg tgctattttg gataatagct
    10141 gtttttgctg tttggtcaat ctctttgtca ccgtcctttt ttagaatgcc tgtcatttcg
    10201 gtaaaggctc cacgagtacc tgagccattt tctcgagaaa caaggtcaat cctgtctgct
    10261 gcttttccag catcagcact gttattgcca caggctgcaa gacctaagcc tgataagcca
    10321 atagctgcca tgatcagcat ttttttgatt gtcataagaa tcacccttat cttttatgat
    10381 attgtgttgt aggcttgcta cacctatagc ttatcaggtc tttgtaaagg tttatccctg
    10441 attaatgtaa agattttgta aaacctaaaa cagccactac caaggctggc cttaagtagc
    10501 tggtagtgac tgtttacttg ttgatagctt ctggtaagaa taaggtaaat tggctgccct
    10561 ctcctagctg acttgtgact gttatctgac cgccaagaag ctgactcagc tcctttacaa
    10621 tggctaggcc taggcctgtt ccaccacttt gcctgctacg tcccttgtta acacgataaa
    10681 agcgctcaaa aatacgatct agctcaattt ggctaatgcc aatcccagta tctgcaactg
    10741 taatggcaac accaccagca accctttgac tggatagctg aattctgccc ccattgtctg
    10801 tatactgtat cgcatttgat aagagattta acatgatctg cgataagagg tattgatcag
    10861 atgtcacaac aatcgaatcc tccaatgcat agcttagctc aagctgcttt tgctctagct
    10921 gtggcctcat gctctgacct gtatacagca ggaagttcct gagctgaaac tctgtcaggt
    10981 caagtggtgt cttgttagcc ttggataagg tcagcaggtg ctcaacaata cgttctagac
    11041 gcaagctttc attgtagata atgtctaaaa agtcttcttt taggcttgtt tcatcgtcag
    11101 gcatttcctt aatcgtttca gcaaagccct tgatcgatgt aaccggtgtt cttaattcgt
    11161 gagaagcatt agcaataaac tccaaattta gcctctcata atgacgaatg gccgtcagat
    11221 catataagag cactaaaatc tccttgacaa catgcgactg gttaaagata ggcacaaggg
    11281 taacctccaa gatcaaatca ccatcatgta ggcctgttaa ttccttcttt aatgtctgct
    11341 tttggtcaaa gacttgatta actaaggcta tcagatccat tcgtttaaga tcctccaaga
    11401 ccacaaaagg tggcttagcc tctggaaaat aagccggtaa ggatttgctg gtcagcaaca
    11461 gctccctttg attggagact aaaagcatgc ccatcgtgag atgagaggtt acagcctcca
    11521 cattttttga taaggctttt agccttgctt ccttttgtaa taggtcactt tttagctctg
    11581 tcagctgctt agcataagca cttaaatcag cctgccccac taggagaaaa tggtcactag
    11641 ctgtcaaaag atggtggtgc aaggctctga attcacgctc ccatctaaat agcatgctca
    11701 agacataaaa gctagctacg agaccagtac acagcactac tagagtcagc acctgatgcg
    11761 gcccttgcca aatcagacca agagcagcca gcaagcaaag ccctagcagc atgctcaaac
    11821 gcctaagatg tcctatcatt ctttagctcc ttaaatttgt agccatagcc gcgaatggtt
    11881 tgaatatact gaggcgcctt aggattgtcc tcgatttttt ctctgagctt gccaatatga
    11941 acgtctacca gacgtgtttc ttggccaaag tcataacccc agatacgctc taatagccgc
    12001 tcacgcgtca gggtcatatt agggtgcttc atgagataga gcagtagctc atattccttt
    12061 ggggttaacg gcaatagctc cttgtcctta tagacctcat gtcgctctgg gtacagacgc
    12121 aattgactca tcgtataaaa aggctcacga cgctcttcac catcaccaga aatctctgct
    12181 tcagtacgcc ttaaaatagc cttgacacgc gctaataatt ctctaggact aaagggcttg
    12241 gtcacataat catctgcccc cagctccaaa gccaaaacct tgtcaaattc atcactttta
    12301 gcagaaacca tcataattgg ggttttgctt cccttagcac gaagcctttt gcagacctcg
    12361 ataccgtcta attgcggcag cataatatct aacacaataa aatcataagg ttctctttca
    12421 gctaatgcca aggcagtacg gccatctgtt accatctctg tcacaaagcc ctccttggcc
    12481 aagtgataat ccagtagcct taagataggc tcctcatcat ctactaataa tactcgtttt
    12541 gtcatttcat agctcccatc agccacatta tatcatattt gtcagtcaat ctaatgacac
    12601 actgcttgac ggcctgaagc ctaaaatcaa tcagaagata aaaagatgtt ttagctttgg
    12661 ctttaccgtc aaatgattgt ataatagagc tatattgatt gaaagaaggt atacctatgg
    12721 caattactca taagaaaaat gaccagctcg aaaagatgat ggcaggcttt gcgtctatcc
    12781 cagattttga taagccttta gagcttaacc aagatggaaa gctagtcact gaaaaaccaa
    12841 agccacaagt caagacagct aagcaggact agcccttatt ggcgtcgtta acatatagaa
    12901 aggatacggt gaatgtcgct tttttcaaat ctgccaccca gcgtgcttca atggtttgcg
    12961 atttttctat ccattatcat tgaagccctg ccttttgtat ttttagggac tattttatct
    13021 ggctgtattg aggttttcgt cacgcctgat ttagttcaaa gatacctccc tcaaaataag
    13081 tggctaagaa ttttatttgg tacctttatt ggctttgttt ttccttcctg tgaatgtggt
    13141 atcattccta ttattaatcg ttttttagaa aagaaggtgc ctagctacac tgctgttccc
    13201 tttttagcaa ccgctccaat tattaatccg attgttttat ttgctaccta ctctgccttt
    13261 gggaattcgc tgcgctttct catgctaagg cttttaggcg ccattttagt ggctgtcagc
    13321 cttggcatca tgctagcctt cattgttgat gagaacattc tcaaggaatc aacccagccg
    13381 gtgcattgtc atacttacag tcacgaaagc ctgccaaaac ggctttactt ggcactggct
    13441 cacgctattg acgaattttt tgatacagga aggtatctag tctttgggac cctgattgct
    13501 tcagccatgc agatttatct gccaacaaag gtgctgacag cgatcggaca tagccctttg
    13561 acagccatct tagtcatgat gctcttagcc tttatcttat ctctttgcag tgaggctgac
    13621 gcctttattg gagcttcgtt attgtcaacc tttggagttg ctcctgtttt agcctttctc
    13681 ttaatcggcc ctatggttga catcaaaaac ctcatgatga tgctcaattc ctttaaggga
    13741 gcctttattg ttcaatttat cagtgtatca gctgtgatga ttaccatata ttgcttactt
    13801 gtgggggtgc tgtgatgatt cgctttttaa ttttagcagg ctattttgag ttgaccatgt
    13861 atctagagct atctggcaag ctaaatcaat atatcaatat tcgttacgct tacttagcct
    13921 atatttctat ggttctatcc tttatccttg cattggtgca gctatacact tggactaaaa
    13981 acatcaagct acacagtcat ttaaaaggta aggtcgctca gctgaccagt ccccttatcc
    14041 tggtctttcc tgttttggtt ggcttgttag tacctacagt cagcttggat tcgacgaccg
    14101 ttgccgccaa gggctatacc tttccattag ccgcaggcgc ttcaaaaaca ggggtcagtg
    14161 atgatggtac tactattcaa tacctaaagc cagacaccag cctgtacttt accaaatccg
    14221 cctatcaaaa ggaaatgctc aatgaactga aaaaatacca aggcaaatca gccatcacca
    14281 ttaccactga caattatatg gaggtaatgg aattaatcta cctttaccca gacgaattcg
    14341 ttgatcgtac gattcagtac actggctttg tctataatga gccaggacat gacagctatc
    14401 aattcctctt tagatttggg attatccatt gtatcgctga ttccggtgtg tatgggcttc
    14461 tgaccactgg taatcaagaa agctatgcca ataacacttg gctgaccgtc aagggccagc
    14521 tgcacatgga atatgacaag accctagagc agcagcttcc tgtccttcaa atcgaggaag
    14581 cacaccaagc cccagagcct gataaccctt atgtctatag ggtattttaa caagcattaa
    14641 gcctccacac ctatgacaca ggtctatgga ggctttttgt taggggacag tacaaagacg
    14701 taattgagtt cgttccattt aaatgaaatg gctaaaagcc gtatagcatc agccttttaa
    14761 aagacgtgtg ctatacggct ttgctattgt tggtaaagcc tttgaggcta ctttctagct
    14821 ctcctcagac aggctacgcc cattggtctc aatgaccctt tgataccaag caaaggattt
    14881 tttcttgtag cgtgtcaaat gaccactgcc atcatcatgt cggtcgacat aaataaagcc
    14941 ataacgctta cttagctgag cagtcgacat agaaacacaa tcaatacagc cccaggaggt
    15001 atagcccata atgtcaacac cgtcctcaat agccttagca acctgcaata aatgctgcct
    15061 catgtaatca atccgataat cgtcctgaac tgtccagtga ccatcctttg tctgtactag
    15121 cttatctttg gcgccaagcc cattttctac aataaagaga ggaatttggt acctatcata
    15181 gtaatcattc aaggttatgc gaaggccaat tggatcaatt tgccagcccc attccgaaga
    15241 gggcagatga ggattaacca agccacctaa aatattgccc tcccctcgtt gataatgatc
    15301 cgggtgatga gactgagtca cactcatgta atagctaaag gataaaaagt caaccgtatg
    15361 ctgcgccaaa agctcactgt cgcccggttc aaattgaatg tcaatgtgct gctccttaaa
    15421 aaaggatttg gcataggaag ggtattttcc tctgacctga atatctgaga acaggagatt
    15481 acgttgctca aactgcttcg cagctaaaat atccctcgga tcagaggtca ttggataggc
    15541 tggcatagcc aaaatcatac agcctatttt aaaagcaggg ttaatcaatc tagcaagcct
    15601 tgtcacacta gcagacgcta ctaattcatg gtgaatcgct tgataaagct cctgcggagt
    15661 cagcttttcc tttggtgtca tgatagcacc actggtaaaa ggcatatgca ggattgaatt
    15721 aacctcattg aaggttaacc aatacttaac cttgttcttg tagcgctgca tgacagttgt
    15781 cgcaaaacgt tcaaagaagc caaccatacg acggtcagtc cagccattat agaccttagc
    15841 tagatgcagt ggggtttcgt agtgagatag ggtcactaaa ggctctatgc catgtgctat
    15901 cagctcatca aacaaatcgt cataaaattg tagccctgct tcgttaggct ctgtctcatc
    15961 gccctgagga aaaatacgag accaagcaat tgatgtccgg aaaaccttaa agcccatttc
    16021 tgcaaagagc gccacgtcct ccttgtagcg gtgataaaaa tcgatggcct ctagcttcaa
    16081 attagctgct gttggctcag ctgtatagtc tcctaagccc ccttctggta aaacatcctg
    16141 aaccgacaag cctttgccat ctgttaaata agctccctca acctgattgg cagcaactgc
    16201 ccctccccac aagaaatcct ttggaaaaca aaccatatta tctcctcctt caattcatct
    16261 ctttagagaa taacgagagc aacatcatgc tgagtgatat gctccttgtt gtcattaaca
    16321 atgatttcga gctgctcaga gctattggtc accacaaatg gagtcactaa agaatagccc
    16381 ttagagccaa tcaattcaag atctatacgt agcagcggct gcccctgctt aacagtatca
    16441 ccagccttaa ccagctgctc aaagccctgt ccttttagct caaccgtatc aataccaaca
    16501 tgaattaaga cgtcaactcc cttggcgttc tttaaagcaa tagcatgctt tgttggaaaa
    16561 agggtgataa cctcgccatc aaatggggca tagacatatt cctcattagg taaaatagcc
    16621 agcccctctc ctaaaagctt agacgaaaag gtttcatctg gcacctctga taatggaagc
    16681 actgtgccaa ccatcggagc ataaatagat tgctttgctg ataagccact ttttactggc
    16741 gtgctatccg agtcagctga cccctcctgg tcaacctcct catcaatgcc aaaaaaccag
    16801 gttaatgtaa aggttagagc aattgttaag cccgctgcaa ttaaggcatt ggtaaaatta
    16861 gcagagctag tcgggctaat gtattgtggc aatccaatta gtgatggcac cacaaaagta
    16921 taagaggcta tattaacaaa gccaatatag gcgcccacaa ggccaccaga aatcattgca
    16981 gcatagagcg gctttttaaa ctttagagta atgccataaa gagcaggctc tgtaattcct
    17041 gccaataaag ctgataagcc tgctgctaag gcaacctgac gggtttgctt ttgctttgat
    17101 tgacatgcta cagccaccgc tgctgatccc tgagctaggt tagaggctag cattgctggg
    17161 aggattaaaa catctggagt tgctacagag gccgccagaa aaataggagc aaaggcccaa
    17221 tgcatacccg tcataacaac aagcggcata attgcaccta aaatagcaag agccagccaa
    17281 ggagcaatat ggtaaatcgc tagcaggcta ttagacaagc cctgtcctat aataacaccc
    17341 agaggtccaa taacaactaa ggctagaaag cctgaaataa aaataatcaa ggtcggctgc
    17401 aggaagctct tcatcacact cggtacaaaa cggttaacct ctcgctcaat gtattgcatc
    17461 aggtaaacca taattaaaat cggaataact gacgcaccat agctagcagg tgtcaccggc
    17521 gctccaaaca aagccatagg tttacctgta gctaccatcg taacaaaagc tgggtgtagt
    17581 aaaatccctg caacagttgc tgctaataca ggtgtgacct taaagcgtgc cgcagctgaa
    17641 tatgcaatca tgattggcat aaaataataa gcagcatctc caaaaaaatt aataaaagca
    17701 actgtttgag agtccgtacc tgctagacca agcataggca ccaagatccc aaccaccttt
    17761 aacataccgc ctcccagtaa ggcaggtatc agtggagtaa tcacactagc tatcgtttca
    17821 atcaaccctt caatcataga ctgcttttga ccagcgctag agctcatatc agtttcatga
    17881 aactgtccta gggtcataaa tgccttataa taattgttaa catcgtttcc taaaataatt
    17941 tgatactgac cgttttggcg catgactcca atcacattag gaataagttt gattttttga
    18001 tctaccactt gtttatcatc tttcaaaacc aagcgtaacc gcgtgatgca gtgggttacc
    18061 tcttgaatat tctgctcacc accaactgct tcaaaaatgg ccttggctgt ttcttgataa
    18121 gtcatttcat tactccttca catttttgac taaacgtttg atatgaaccg ttaaatacaa
    18181 aagctcacta gagctaagct gataatggta tgcttttttc atgtgatggc taatttgcct
    18241 aacacagtga tattcctctg ggtatttatc cttaaccatc agcagcaaat cagtctcgtc
    18301 atcatcataa gccatgcctg ataacacgcg ctgagcaaat agcttcacat gagtgataaa
    18361 gcgataataa tcaatagaga cttcatcaag ctctgtctta aaatcagcct tgaccttctg
    18421 ttcaatgtaa gacacaattt ctgtcattcg atgaggctcc ttgaaaggat tatcaaggct
    18481 cgcgttgaca aagtgcatcg caataaacga agcttcatct acagccagag cgactcctag
    18541 ctcactggca atgacctcta aggccttaac gccaatcgca tattcatcag gataataccg
    18601 tctaatctcc cagcgcaagg gatcactaat gatcatcccc tgcttatgtc tttcaatagc
    18661 tgaatgaata tggtctgtca aattgatata gagtatttca tctaaatttt tacccagctt
    18721 aattttccct agattaataa gcctctctga gcaagcaacc acctcttgcg gaacagcaat
    18781 aaataattca gtaaaacggt tcatattgtc actatttttt aaaacaaatg acgcttcgat
    18841 agcttcacta tcgatatggt caccaattct tttcttaaaa gcaatcccct ttcccatcaa
    18901 aagaatatct agcccctgat ggttggtcga aatcgctgca ttatggttta aaacgcgttt
    18961 aataatcata aaagtcctag tccctcattg cttcacaata aaaaatgacc tatccacagc
    19021 atgctaaaag gccacactgg aataggtccc tgctcacaaa actgtgataa catcctttaa
    19081 tattctgatt catttgtcat tagcacgctt accctaagta atcacatcta ataacgtttt
    19141 cattttatca tctcctaaag gtcctgtcaa gcgttttcaa aaggctgttt gacatttgcc
    19201 tctaaacgaa ccccctcatt ctctttggcc aacagccgat aatctgaggc tttcctctta
    19261 aagtatgcct tctaatagtc ccttcataaa gtcctcagag tgaaattcac cgatatcatc
    19321 aatagcctca ccaaagccaa tcagcttcac tgggatatcc aattcctgac gaatagctag
    19381 gacaattccc cccttagctg taccgtcaat cttagttaaa atcaagcctg tgagcggtgt
    19441 gatttttgaa aactccttag cctgactcag agcattttgc cccgttgagg catcgagcgc
    19501 tagcagggtt tcgtgtgggg catcaggtat gacacgctta atgattcgtc ctattttttc
    19561 aagctctgcc attaggttgt ccttattttg caggcggcct gcggtatcaa tcaggagaat
    19621 atctgccctt tcagcaacag ccctctcaac gccatcaaag accacagagg ccggatctgc
    19681 tttttcaggg cctgtaatga ccggcacatc aacccgtcgt ccccattcaa ccagctgggc
    19741 aaccgcgcct gctcggaagg tatcagctgc aacaagcata accttttttc cctcttgctt
    19801 ataccgataa gctagctttc caattgatgt tgtcttacca acgccattca ccccaacaaa
    19861 gagcataacg gtcaagccag gctgataatg aatcgcttca ttgtagcggc catccccctc
    19921 ataaatagcc actagcttat caatgataag acgctttaga gcctctggct ttttagcatt
    19981 ttcaagctta gcctcatagc gcaattcttc agtcaaggtt gtggcaacat gaacaccaac
    20041 atctgagaga atcaaaagct cctctaagtc ctcaaagaag tcctcgtcaa cacgtctaaa
    20101 gttagcaaag aagctgttca agcgtgctga aaagcctgta cgggttttct ttaagctgcg
    20161 cttgtatttt tcctgatcag attcagctga tagggtctct tgcttttggc cttcctcagc
    20221 tggctgatca gctgaaccag caggtgcttg agctgctact tgatactcag catttgtctc
    20281 tgcctgatct tctgttgatg cgtctgcgct ctcgttacta tgctctgact tagccctatc
    20341 atgcttagcc tcctccatag cctcgtgctg gcttaggctc tcacctgcct gatccaaggt
    20401 cttgtcatca gtagctgcta actctagctc cggctctctt tctaaaagaa aagctcctct
    20461 agctgctgga tcaagccctt cagcttgctc tgaagcagcc tcgtctgaga gctcagcctg
    20521 tttgctagtg tcatcggtcc tagagaccac atcagctgcc actgcatgag catttgtatc
    20581 tgataaggcc tccttttcag actcaatcgt atcctttgac gttatgtcct ccgacaatac
    20641 ctctgtagtg gcagcctctt gctcagcaac cttagtctta tccttttttc caaataagcg
    20701 ttcaaataat cccattagcc ttcctcattt aaaatatatt tccaaatagc ctcagccaca
    20761 cctgattggt cattggttag ggtagtcact gcatctgcca cttccttagc ctgatcaacc
    20821 gcattggcca tagccacacc aagacctgcc cattgtagca tgctaaagtc attggcctca
    20881 tctcccatcg ccatgacatg cttggcctcc aagcccaagt gctgacaaag caggtccaaa
    20941 ccaaatgcct tatgaatccc cttaggcata atctcaaaga tgatgtctcg tgatttaaag
    21001 gcctcaaaat cctcaaagat agtctttgga agccttgcaa gctgctgatc caagaccttt
    21061 ggatccgtca ccgtaacaat tttattgtat gtgatgtcct ttggcagctc agcaaatgat
    21121 ttaaggctaa caaagttcag caagggactt gccaagtgat actgagagcg tctgccatca
    21181 ttgcctgata gactataaac agtaccatca ctgataacat cagtaggtaa gccaaccgct
    21241 gccaactgct gatgaatgtc ataaacctca gcaaggctta gagcgctttt atctaaaata
    21301 tgaccagtat ttcgttgaac cagaccgcca ttaaaggtaa tgctatagtt ctcttcacct
    21361 agcaaatcca gctcctcaag caaatttccg atagccttaa gaggacgtcc ggttgtgata
    21421 acaaccttaa ctcctttttc cttagctgct gctagagctt ttttgttctc atcactaacg
    21481 attttttcgg tattatagag agtcccatct aaatctagag ctaaaagctt tatacgcgtc
    21541 atttacacca atccctccaa ataagttaac actgctgagt cattacaatg accaataacc
    21601 tgatcagaaa tcgctttgat ttcaggcctt gcattttcag tagcaatagc ctgccctgca
    21661 aaggacagca tttgataatc atttagatta tcgccaaagg caatggtctt ttccggtaaa
    21721 atgcctaggt gctgacacag ctgatccatg ccaaagccct tatgaacctc ttttaggata
    21781 atatcaatcg aatcaaagcc agtcgtcacc gcagaagcat aggacagctc ctgatttagc
    21841 cagtcactgc cagctaagac tgtttctcct gtaaaggtcg ttgaggcttt aaaaacagtg
    21901 tcatcaacaa tatcctgcag acaatcaata agctgaacat tttcataata ataatgcatt
    21961 ttttggatat aatcctccgt agctcctttg agcacatagg ctgccttttg ccctgaaaag
    22021 aggatcccag actgattgta ataaggattg gcaagaattt tctctacaat gtcatgacac
    22081 tgctgcttgg tcatgacatc agcaaaaaga atgtccctct tgtattgcac cacagaccca
    22141 ttctcagcga taatggcaat gtcatctaaa aaaggctcaa acaagtgatc aatggctaaa
    22201 agcgaacgcc cactagaaac tgtaaagaga atcccttttt ctcttagctt aggcaacaga
    22261 gctgccaagc gctccttgtc ataagttccg tcctctctta aaaaggttcc gtccatatct
    22321 gttgctatca atttaaccat acaatttaac catttccttt ttagggagat actgattcag
    22381 ctattcagct ctcccaaaaa tctctttttc cattatacca tatctaaaca aaaagggcgt
    22441 gcctgtccta acacgtcctt gttttaaggc tttataattt ctgtagtggg taactccact
    22501 gtggagatta ttgagccctt attccaaggc tttctttatg ttctattgta tcaatttcct
    22561 tattccaatt tctgttgcaa ttaactttaa catacaatct aaccatttca ctttcaaggg
    22621 agtgcaaaac ccgagtgggg tgtgcaactc aaatcccagt ataactcctt tcgttatacc
    22681 acaggtagac caaaaaaggg cgtgccatct gacataccct tgttttaaca gtcaatctga
    22741 gctccgtttt taaaggctaa acttctttat ctccatactc tcaacgctta tttgccataa
    22801 ttcttaattg aagcccgtca ctaagttttc ttgttactaa agagttgagt aatgaatcta
    22861 tctagactga tgatttttct ccttaaaagc ttcatatagt tttttatata acgctttctt
    22921 ttcttttttc tgagcattaa actctttttt accgtaatca aaatttgcta ccacaaaccc
    22981 cttgttattg ttagaaaaat caaaaaattc catttcgatt aatttgttat tcttagaatc
    23041 ttctatagta ttctctaaat gattgttgaa ttgtttaaca tcttcttcac taactccaaa
    23101 acccatagca gctccgtctg caatgatgtt tgaaaatatt tcttctgaag atgctgcttc
    23161 ttttaccctt attaggtata tggcttcttc tgtttctaat tgtcttactt tattccattt
    23221 ttgggtatca ctagaagaga tcgtatagac tgttaaatct accgtaggtt tattgggatt
    23281 ttcttttttt attacttgtt ttcccactaa gaaaattgcg agtattccaa ttaataatat
    23341 caacgtcata taagctttct ttttcatatc tcactcccta tatctttcaa atcaatgata
    23401 acatcaacct tattatatac agctggatca tgtgttgcta taataacata tttattttcg
    23461 gctgtttcac tcaataataa attaatgatt tcttttccaa tctcactatc caaagctcct
    23521 gtaggttcat ccgctaaaat aattttacgt ggcttcatta acattcttgc aatagctaca
    23581 cgctgaacct gtcctccaga taattcatat attttctgat ttaaatagtc attagaaagt
    23641 cctacttttt caagtacatc agctattatt tttttatctt tattgatgag tctcaaatta
    23701 tcatatactg ttttgttttc tattaaagaa taattctgga atacataccc aataatagtt
    23761 ttaaagaaag ttctttcttt tgtcttccaa atatcctgct catcaactaa aacctttcca
    23821 ctgtcaattt tttctagtct tcctatgata ttaagtagtg tacttttacc tgaaccagag
    23881 cctccaatca atgcgtagct ttttccagct tcaaacgtta aatttaaatc tgtgaatatc
    23941 ttttttgagc cgaatttttt ggtaacattc aaaacttcaa ttgccattag tcatctcctt
    24001 ttagaatttg tgtatatttt tcagataatt ttctaaaact cattattgtt gaaaaaatta
    24061 aaaccattaa agaagcaatg ccaatatata atagctctac ttgtcctgtc aacataaatg
    24121 tcaatagaat aaccattgta atagtcacaa taaaatagtt gagacttgaa atggctatac
    24181 gtgttttcga taggcctaaa atgatttttt taacatagtc attctgtttt aaggcaacaa
    24241 acatttgagc atactgataa atgagtagaa atacgattcc acaaataatt atttgcagta
    24301 tttttgaaag gaaaatttga tgctctaagg attgaatatt aagttttaca gtttggtaaa
    24361 cctcgactgg attgattgaa aaattcaaac tagcactcaa atcgttgatt ttcttaattg
    24421 cttccgaact aaaaagtgag ttatatatta tattacttgc caaaataaaa tcgttatttt
    24481 ctatcatttt atcagtatct agcacaacga ctatattatc cttactatct gtcacacttt
    24541 ccaaaggtag attatcttta ttttcaggaa cactactacc attttcattg aaatagaaaa
    24601 attcttgccc atcaggaatg acttgcaccg taaggtcatc ttttgtatag tttgtaccag
    24661 taaattgttc tgctacaact gtattctcga ttgatgcctt attctcttta aatttatgag
    24721 gaatatagat ggttgctatt ttattatcta atgattgata gttcgttcca ttaactttat
    24781 tttgtacctt agcacctgtt tgattaatat aaaccagttc cttattaact tctggatgcg
    24841 ttattccatc actttttaat tgcttagaaa aatcttctgt aacatcagaa gctgccatat
    24901 attctggaac ataggctgaa gatgatttga tatatataaa atccagtttt tttaaggctt
    24961 tagcaatctc tacgtactta gctcctgagt catttgcttc ttctccatta gtaacagatt
    25021 cattttcaat acccaaaaac tctggtcttt tccaatcttt tactgcactc catggtttta
    25081 aatgctttat ctgcatgttt atctttgatt gactagcctt tgtttcccgt aaaaagactc
    25141 ctgaaacaac tattatgata gaaataaccg caagccatac gataaaaatg aggctatttt
    25201 tggccttatt ttttataatt tcaataggtt tttcaacctt aatagttagc caaaatagaa
    25261 caaaggtgat gatgtcaatg atttgaaata tgatcaaatt agttaaaagc atagaaaaaa
    25321 ataacttgga actgtaggtg aaaaaaccac tacccaaaaa agaactataa gaaatcatca
    25381 ataaagcggc cataaccagt tcaaaagtaa atgacatgaa ataatctctt cttaggtcgt
    25441 gtacaggtaa tcctaaagaa cgtcttatca ctccttcttt aatctgtctc gctctaacaa
    25501 caaatagaac aactaataag gttaagtaaa ttgaaatcat tagcaataat ctcaacggac
    25561 cagtaaattg tatcattccc cctatctgcc aagggtaagc cagatatatg acttgaagac
    25621 ctgtagatgt gagcggtttt aaactatttg aatctaattt ccctagggta taatacatcc
    25681 ctgtgattgg tgcagacttt aattgttcat gattagtatt atcaaacttg atataagtca
    25741 actgccccga attttgaact accggtttgt aaatggtaac ttttttctct tttgataggt
    25801 cactaatcgt ttgatacact tcttcattag aaagattgct tttcccttga atggagaagg
    25861 caccatcaat tggtaaaggt attggttttt gagtatcatt aatactaacc agaccaatgg
    25921 cagcaattaa acaaaagaag aatccaacaa tgcataattt taatttcata agcacctacc
    25981 tatatcataa aaggccctat agcattattg ggcctttagc tttcataaac catttttaaa
    26041 atgtaaagta attccaatgt gtatttaatc gaacatcatt ccagcttttt gttgcgcttg
    26101 agtttgccca tccatatttt tgagaatctc tatccttaac tgttccccat agattagtta
    26161 ctgaagattt tgaaccaata ttatttggag acttaacata gtcattagaa taaccatagt
    26221 tatcacttac accataattc cattcatcaa taattggata tggagctgga tgcgctgttg
    26281 ctgcactaac aactctagct gtagcagcag atccaaaact taaagtgctt acagcaagca
    26341 aaactaatgt tttgtcacca atttttcata ttagttctca ttggatagat tgttaaaaat
    26401 atttgaacaa tctaaataat atattattat ttattagcat aatatcatat tattatttga
    26461 attacaagat gctaaattgc aagtaaaagt tagtcatcct atagaaatta tccgagtgac
    26521 ttgttgttca aaattttccc caattttaaa aagagatgaa actctgcgtt ggattgatcc
    26581 tttaagcgac ccaattcatt gaaaaaatct gatgcagcat tggcagatag gtctaaacgc
    26641 ttcaaaaaaa cactcatctt ctggtactca gagttgatca aatcatttaa gacatgtctt
    26701 ctttcagata agctgtcttc acgcttctga taggctcttt tctggcgtag aaagtcctgc
    26761 tcggcatcat ccatctcccg aagcttacga taaatagcca cttcctctac aattctgtct
    26821 gccatgctct aaactctcct gctaactgac gatccgtttc aagcttgcta tcaataaccg
    26881 tctgaatatc tctattcaag ttttcaaagt ctgtggccaa ggctgacagc ttgctgacct
    26941 tggattgagt atagtcctga aagtcttgga caaagcggtc atatgtgata ccataagaag
    27001 caaataaggc ctgcacctca tagtagggca gctcatgaaa agagttgaag tcaatcgccg
    27061 accacacttc cataagcttt gcgtctgcaa ccgttttatg atccagagct tcatcagccc
    27121 cctctcgagc agccttagcc atggacgagc ctaggatcat tccctgtgcc gcatctaaaa
    27181 agagctcctc agaactactg atccccttgc cggtagactg ccagtgtttt ttgagctgat
    27241 tgtagcttga catgctcttt tttgaggcaa ggacagttaa ataggcccga ctcacaaggt
    27301 attgtgttcc aatgagctta ccgtctctat ctacaatctg acccttttga ttaaaacgat
    27361 aagctcctaa atcgtgataa tacaaggggt tggctgataa gagcatagca tcgacattcc
    27421 gagaaatagc taaatcatca gttccaaaat aggcaccaaa attgccaatg ccatcaaaat
    27481 taatgcggaa attattgtac atattgctat tagccttaac ccatgtgata gcttcagctg
    27541 acatgccgcg aacagggtct ggaccattaa aggttgttgc tgggatctta tgttctgcgg
    27601 caactattag tgctagataa gctccgagag agtgacctgt ggttgttaag gcagaatgag
    27661 ggtactttct tttgacctgt tgataaaact tttgagcaga tcgtaattgg ttttcggcaa
    27721 taacaaaatt gccaccatca atattgccgc tgactaaatc atcttgattg ccccgaatga
    27781 gcagctgcca atccgtatca agatctctgg aatccgcagc atttgtccct gcataggcaa
    27841 tcacaacctg agaggtatcg atatcacctt taacaatagg ggctacagcc attgcctgca
    27901 taccgttgtc attggtttta tgggcatcgt tgttattgtc ctgaactaag aggactcggt
    27961 attgtcgttt agtgatagga tcttttacag ttttaccagc aacaataaca aggtctccat
    28021 ttgatttagc tttgctaggt tcgacattat aaacctgttt agccaactca ttataactac
    28081 tatccgatat cgccatatta atcctcctga ttgtcctttg aataaatgac agtaacacct
    28141 acaagagatg ttttattaat cttgtcaatc ctatccataa ttcttggttt ggtatcagtt
    28201 tcaggctttt ccatcttttc tgtatcatca tcagtaacaa ttcctcgtat tttctcaaga
    28261 ctagacaagc catcaaacga aaagcctatt tcattttctc catttataat cactatcgtt
    28321 ccccacgaac ctgtttcccg agaatgtccc cagcctgtaa acttaacttc tttaacccct
    28381 tcatagtcat gaaccagcag cttagcaata ctggtttcca agtccctttt ttgttgttcc
    28441 tctgttcttt tgccattcaa acgaaaaacc attatgatcg ctcctattac tattattaag
    28501 cctagccata gcctttgctt attggtctta actgtcatca tgtcctcctt tcactctttt
    28561 gctatgcgtc cgtcactcta aggaaggcag catgactaat tagggtgaaa tcaacgccaa
    28621 atcttattta tattattctc attttgtaat taaattataa tatacagaca tctacttgtc
    28681 aatatattat gtccttagtt acttttttgg tatattttaa tcaaaacaag ccgtactaag
    28741 ttccaggagc atgtcaaaaa cagcagctta ctgctagcca atccttgtgc tttgtccttt
    28801 ggaaagccaa aaaacctacc atgacgatag gtttttttat agcttattct tggttatcat
    28861 ctgctacatg tagaaataca gctaaaacta agctctgtcc tagagttatg acaagtaagt
    28921 cagatcctgc gtatccttga gcttaacaga tactacctta gaaacaccag attcttgcat
    28981 ggtaatccca taaatactgt ctgctgctgc cattgtcccc ttgcggtggg taaccacgat
    29041 aaactgacta tccttgtcaa aacgattgag ataatctcca aaacgcttga cattggcctc
    29101 atcaagggcc gcctcaacct catctaaaat cacaaaggga atggtcttaa tgcggataat
    29161 agcaaataaa agggctagcg ctgataaggc tttttctccg ccagacatca cattcaaaga
    29221 ttgaagcttt ttaccaggcg gttgcactga aatatctact ccagcagaaa gcagatcagt
    29281 ctctgtcaac atcaagtccg ctgagccccc gccaaacatc tgcctaaagg tctccttaaa
    29341 gctatcacga atagcctcaa aggtaaccct aaagcgtgcc ttaacctcat ggtccatatt
    29401 gccaatcgta tctaccaaga gattcttggc cttgataagg tcagcccttt gaccatttaa
    29461 gaaggccaaa cgctcactaa cctcatcaaa ttgagcaata gcatcactat tgattgggcc
    29521 tagggcacga atgctttgct gaacctgctg caatttctgt cttgctgctg ccatgtcagt
    29581 gtcattgatt gggcttgcct gctccttggc ctcctctaag cttagctgaa gctcctctga
    29641 taggcttcta gcgtgctgcc gcaaacgacc aataacctgc tctaagtcag cctccagtct
    29701 tgcctgctga cgaatgaacg cttcattttt cttggcttcc ttaagcaatt gagcctctag
    29761 ctcctccagt ctggcgtcat agtcctcacc ttcaaagcgc agctgaatga agcgctcctg
    29821 agtcttgatc ttgtcttgat tagcctctgt cagctgattt tctaggtgag gcaattggtc
    29881 aatggcctcc tgactaacct gatgtgataa aacagtctcc aaattagcta attccttctg
    29941 accctgagca atcatcgtct ccaagcgacg ctggttagct gcttcaaact ttttctcgtt
    30001 gagcaaatct cgctctttaa gacgagcctg agataattcc tggctaagct ggtccttctt
    30061 ttgcttaatc gtatctttat tttccttaat ttgctcaatt tctgacgtta aggctgattt
    30121 ttcatcagct aggagctgca atgcctcctc cagcctcgct ttttctgata ataagcgctc
    30181 actagactga ccagtctgac ggttgctgag aagctctagc agctcttttg agtcagccag
    30241 cttttctgct agctgctgat aggccaattg tgttttttgc tcgaccagtc ttgcttgctc
    30301 accagccagc ttagtatcag cctgcgcagc ctttttagcc ttcaaatcag cctgtacagc
    30361 agctactgct ttttcagatt ccttgatctg ctcagaaagc aaggctaatt ccttctcaat
    30421 ctgctctagc tctggcttga taaaggttgt gctattgtga cgattagtcc cccctgaaaa
    30481 ggcaccaccg ggacgcagct cggtaccatc aagcgttaca atcctgacct tataatgcag
    30541 ctgcttagct gcctgattag catgatcaat ggtatcaaaa atagccgtca cacctaacag
    30601 gctttgtaca atagcgacca aagagggctc ataggtcacc aaagaatcag ctgtgcctaa
    30661 atagccctga caagccctga gctgcttgag agtcacctca gaaagctgac gggccttaat
    30721 cgttgtcaga ggtaaaaagg tcgcacgccc ctgacgatta gcctttaaaa aggctatcgc
    30781 tcgcttggct gctgcctcat ctgccacgat aatatgctga ctactagctc ccaaagcaat
    30841 ctcaagtgcc gtttgatact gactatcaaa ggtcaaatgc tcactaactg ctcctaaaat
    30901 accatctagc ttaccagcag cctgaagcac tgccctaaca cctgcgtaaa attgactatg
    30961 atttttttgg atagaaacca aactagccct acgagcctcc ttggcttttt tctgatccaa
    31021 caaatcaaaa agccttgtct gtccctgatg ataatcctgc tccaaggcct caactgtctt
    31081 tgctagctct tgataatcag ctaggagctg ctcaagtctt gattgactag cttgataagc
    31141 caaaagagca gtctgggtgt cctgactgag ctgattgacc ttctcttgta ggacttggta
    31201 ttcctgcgcc tgactggctt tcgcctgact ttccttatcc agctgcgcta caatagcggt
    31261 taattggttt gacacatcag cctcttgctg gagcagacca acaaaatcct cacgaagagc
    31321 ctcaagcagc tgatctggat cgctagaaaa tcgctcaagc tcctgagaaa gctcgctgac
    31381 cttggtatta aactcagcta aggcttgatg gatttcatct agctgacgac tcttttgctg
    31441 atgctcctgt tgaaaggcaa gcaattgctc ctgagcctgc tgcctgcgct gactggcttc
    31501 tgttttcttt tcctgctttt gactaaggtc cagcttgatg aggtcaatct gtcgctccag
    31561 atctgatatg acctttgtca attctagcaa atcagcctgc gtctgctcag ctacagcaga
    31621 gagcttttgc cgcttggttt ttagacggtg attttccgcc tctagactct gacgcttcct
    31681 atgataggcc gctagatcct cacgaagagc tactaaggcc ttttcttgag cctcctgctc
    31741 catgcggtct tgctctatat ccttgaccaa aatatccagc tgcagctgct tacgatcagc
    31801 atctaaggct aaaaattgcc tagcagtttt cgcctgtctt tctagaggac cagcttgatg
    31861 ctcaagctca tagataatat cgtctaagcg gtcaagatta tcttgagttt ggtttagctt
    31921 agtttgcgtc tccttcttgc gggtcttgta tttcaaaact ccagctgcct cttcaaagat
    31981 ggcccgtctt tcctctggct tactattgaa aatctcctca acacgacctt gagaaataat
    32041 agagaacgaa tcgcgcccta gtcctgtatc cataaacagc tcgtgaatat ctcttagcct
    32101 aacttttttg ccatcaatca gataatcact gtcgccattg cgatagatat gcctctccac
    32161 acgaatctct ttctgagcat tcttaataaa ggcatctgaa ttatccaaga caacagccac
    32221 ctctgcataa ttcaagggac tccgatgctc agttccagca aagatcacat ctggcatctt
    32281 gccaccgcgc aggcttttgg cactggcctc accaagtgcc caacgaaggc tttctgtcac
    32341 attacttttt ccagagccat ttggccctac aacagctgtg acccccttat caaagataat
    32401 cttggtctta tctgcaaaag acttaaagcc ctgcatttgt atttctttta aaaacattta
    32461 gacctcacta agttgggcca gggcattttt agcagcgtcc tgctctgcca gttttttaga
    32521 tctacctgtc cccttgctaa gatgatcctc accaaccaat acagctacct caaattgctt
    32581 agcatgagct ggtccagtct cgctaatcac ctgataatca atcacaacat cacccttagc
    32641 ctgtaacaac tcctgcaagc aggttttata atccttgacc ttctcaaaag ttccctgctc
    32701 aacctgtgga atcataacct gatttaaaaa gcgacgaacc tcttcaatgc ctttatccaa
    32761 aagaagagca cccaaaaaag cctcgaacaa atcgcctaaa atcgtatcac gatgacggcc
    32821 tcctgatttt tcctcgcccc tgccaagctt aatataagca tcaaacgaac aatagcgtga
    32881 aaagcctgct aagctttcct ctctgacaat cgttgatctg agttttgaca tatcaccctc
    32941 agtctgctta ggatacttgg caaagaggta ttctgaaata attaactgta gaacggcgtc
    33001 tcctaaaaat tccaaacgct cattatgtga aatgtttagg aggcgatgct cattagcata
    33061 agaggtatgt gtaaaggcag tctctagtaa tcttttatca tcaaaacgga tattaaaaga
    33121 gttttccagc agggcctcaa gctttttcat catgacaaat ctccttttct aatgtcctta
    33181 taaaccattc tattataaca aaaatccact tgaaaggctt atcacaagtg gatttttcag
    33241 aaatattgta ccaaataggc acgagctatt gactgctgct a
//
LOCUS       DARYXZ010000023        33242 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYXZ010000023 DARYXZ010000000
VERSION     DARYXZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33242
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(310..909)
                     /locus_tag="TV186_000975"
     CDS             complement(310..909)
                     /locus_tag="TV186_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1532380.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            complement(1487..3433)
                     /locus_tag="TV186_000976"
     CDS             complement(1487..3433)
                     /locus_tag="TV186_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1532381.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TV186_000977"
     CDS             complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TV186_000977"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL1532382.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            complement(4338..5051)
                     /locus_tag="TV186_000978"
     CDS             complement(4338..5051)
                     /locus_tag="TV186_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1532383.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            complement(5486..6409)
                     /locus_tag="TV186_000979"
     CDS             complement(5486..6409)
                     /locus_tag="TV186_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL1532384.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            complement(6421..7479)
                     /locus_tag="TV186_000980"
     CDS             complement(6421..7479)
                     /locus_tag="TV186_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL1532385.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            complement(7611..8603)
                     /locus_tag="TV186_000981"
     CDS             complement(7611..8603)
                     /locus_tag="TV186_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1532386.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TV186_000982"
     CDS             complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TV186_000982"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL1532387.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TV186_000983"
     CDS             complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TV186_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL1532388.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(11117..11356)
                     /locus_tag="TV186_000984"
     CDS             complement(11117..11356)
                     /locus_tag="TV186_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL1532389.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TV186_000985"
     CDS             complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TV186_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL1532390.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(12069..12686)
                     /locus_tag="TV186_000986"
     CDS             complement(12069..12686)
                     /locus_tag="TV186_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1532391.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(12679..13902)
                     /locus_tag="TV186_000987"
     CDS             complement(12679..13902)
                     /locus_tag="TV186_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1532392.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(13914..14624)
                     /locus_tag="TV186_000988"
     CDS             complement(13914..14624)
                     /locus_tag="TV186_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532393.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(14624..15886)
                     /locus_tag="TV186_000989"
     CDS             complement(14624..15886)
                     /locus_tag="TV186_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL1532394.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TV186_000990"
     CDS             complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TV186_000990"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL1532395.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TV186_000991"
     CDS             complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TV186_000991"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL1532396.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(20909..21844)
                     /locus_tag="TV186_000992"
     CDS             complement(20909..21844)
                     /locus_tag="TV186_000992"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL1532397.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(21902..23161)
                     /locus_tag="TV186_000993"
     CDS             complement(21902..23161)
                     /locus_tag="TV186_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL1532398.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TV186_000994"
     CDS             complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TV186_000994"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL1532399.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            24060..24674
                     /locus_tag="TV186_000995"
     CDS             24060..24674
                     /locus_tag="TV186_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1532400.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(24755..25645)
                     /locus_tag="TV186_000996"
     CDS             complement(24755..25645)
                     /locus_tag="TV186_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1532401.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(25635..26093)
                     /locus_tag="TV186_000997"
     CDS             complement(25635..26093)
                     /locus_tag="TV186_000997"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1532402.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(26321..27250)
                     /locus_tag="TV186_000998"
     CDS             complement(26321..27250)
                     /locus_tag="TV186_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1532403.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TV186_000999"
     CDS             complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TV186_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL1532404.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(27972..28304)
                     /locus_tag="TV186_001000"
     CDS             complement(27972..28304)
                     /locus_tag="TV186_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL1532405.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TV186_001001"
     CDS             complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TV186_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL1532406.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(28665..28739)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(28861..30054)
                     /locus_tag="TV186_001002"
     CDS             complement(28861..30054)
                     /locus_tag="TV186_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL1532407.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            30319..30936
                     /locus_tag="TV186_001003"
     CDS             30319..30936
                     /locus_tag="TV186_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL1532408.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(31234..32463)
                     /locus_tag="TV186_001004"
     CDS             complement(31234..32463)
                     /locus_tag="TV186_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1532409.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(32498..33154)
                     /locus_tag="TV186_001005"
     CDS             complement(32498..33154)
                     /locus_tag="TV186_001005"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532410.1"
                     /translation="MIRNDIYSYHFQCTYKLNTNIAISDDWNQELVNIISLQDTLITK
                     YNKILDKSDEVLMQLKSEVNLGLNGLAGVLFYLSSISYDNEIIEKGIDFILESLVEDS
                     DGNRGVLISENSVSPYLSNGTAGIVQLLIYVNSDKYIKDIKNLSESLLVEFAQFSGLW
                     NGMLGIAMTLLQVFRLTNDTLYLEKACELLISSKIMSEHHIKLQYEFRYAVSIFNQVK
                     "
BASE COUNT        10053 a         7691 c         5903 g         9595 t
ORIGIN      
        1 aatcaaaaga agatagcatt tctgctatct cactgttagc cactacttac aggtaaaaat
       61 acaccttgtc tatttgtagt ttaactatcc atttaatcca tcaataagcc aaaccagacc
      121 gtttaatcat ctacccagcc ttacacatag tattttctca catcatttgt agaattgctt
      181 tctccttgca tgtcaccatc tcgtcttaaa cgttcgtaaa gggctgtttg atcttttcta
      241 actattttag aaaattattt tgctgttctg atgaggttaa tctcgttaga tcagtcatgc
      301 tggaggtagc taccgtatgg gagcgtcaaa ataagtcagc tgataatccc ctataatacg
      361 attgagcttt tcgccatagc tagtatctgt ggcatatgtg cctgttaaac tagcggtggc
      421 ctgctgataa cttgtatgaa tacctcggtg agtagggcga taaagcgggt cactcaaaac
      481 cctagcataa tcctcaaagc aggctgttaa gctgccatag gaccgaaaag aagcgtcaat
      541 tagataaagg ttgccttggc catcatcttc caaggtaggt aaaataactg attttccttt
      601 atagcttcct ttgataccaa aaaaattata atagggctct tgacttagct tagattgacc
      661 atttgctgac tccaaaatag cctgtgccat catgactgag gcatagagct tgtttcgctg
      721 cgcaactgcc tgagcggaat gactaatctt gctcacaaat agcatggttg agctattggc
      781 atgaggctta aggtgatcct tagctgacgc taaggtccaa aggctaagca acatgctgcc
      841 taaaacaata ccagcagcca gccaagagct agcttccctg tggcttcttc tagctttcct
      901 cctcttcaac agaaatatcc tcacttcctt gcttttaaac ctagtatagc aaaaattaaa
      961 agcaaaatgt agccagacca catgctcacc tcaaaaacag gccttatgac ttctaaaaag
     1021 acctagcagc cacaacaggc gcataaaaag tttttaacaa gaaaagaaga ctttgctgta
     1081 tttcaatcca cgctcctgca aagggagcga tacaaaaaat aaatggaata tctacaatca
     1141 aatgatttca atgtttagct atttcaagaa tatatcttat ttttgataga tgttactata
     1201 ggaaaaacgt tgatagtatc tactttaatt gatactataa ttcgaaaata actgtttcgc
     1261 acgtttggtg tggcttagtt tagcagggct attgggtcac tgcttagcta ttctagatca
     1321 gattgattct ctctaaatat tagcttttcg ccagtcatca ctactagcaa caaacaaaac
     1381 gcacgacatc atgtaaaaac aggctgatgt catgcgtctg atgttttatt aagactaggt
     1441 ctaattcaga agctttccct agtacttgtg gctttatagc cagtaactaa gcttttttac
     1501 gaagtgcgcc aaagagaata ccagaaacca ctgctccaat agcgacaaac aataggtata
     1561 agaaaggatt gcttgtcaaa gcgataacga agataccgcc atgtggtgcg attaatttga
     1621 cacctgctag accaacaaga gcacctgtta gggcagagcc agcgataaag cttgggatag
     1681 cgcgtgctgg gtctgctgca ccaaacggaa tggctccttc tgtaatgaag gaaagtccca
     1741 taataatgtt ggtcaagcca gattcacgct cttccttggt aaatttgtct ttaaataaga
     1801 gtgttgccac aaaaacagct agaggaggca ccataccacc tgccatgaca gcagccataa
     1861 caactgaccc accgcttgca acggttgcag caagtgttcc tgtaccaaag acataggctg
     1921 ccttattcac tggaccaccc atatcaacag ccatcatgcc gccaacaaga agtcccataa
     1981 gaactgcaga gctacctgac agactttcta agaagtggtt caatgctgta ttgatagctg
     2041 ccataggaat attgatcagc agcatcaaaa gacctgtcac aagaacacca agtaatgggt
     2101 aaagaaggat tgacttgacc ccttcaagcg aacgcggaag ccctgcaagc acttgacgaa
     2161 gagcaagaat tactccccct gcaaggaagc cacctacaag cgcaccaaga aatccagacg
     2221 gtactcccgc taatgatagg ctagcctcac cgccagcagc aaatggaacc tttccaaaag
     2281 caagaccgct agaagcaatg gcacctgcca caaagcctgc cacaagacct ggcttttcag
     2341 cgatagaata agcaatgtag cctgctagca ctggcaacat gaatgaaaag gccgcaccac
     2401 caatatgttt aaagatagct gctatttcat ggtaggatcc caaattagac agctgatcct
     2461 ttggtacccc aagcatgttg tcaagcaaga aggcaagagc aattaggatt ccaccaccaa
     2521 ttacaaatgg cagcatttgt gatacaccac tcatcaggtg cttgtagaag gctccgccta
     2581 ggcttgtctt ttgagctgct tttgcttgtt cagcagcgcc attcttggca tgataaacac
     2641 taccagcatt gtttaaaatc agtgaaatca attcctcgct tttcttaata ccatctgcta
     2701 caggacgagc aatcaattgc ttaccatcaa agcgatccat ctcaaccgcc ttatcagcag
     2761 cgataatcac tcccttggcc tgcttgatgt catcagctgt caggcgattg ccaacccctg
     2821 aagcaccgtt ggtttcaacc ttgatgccga cacccatctg tgcagcctgc tttttcaagg
     2881 cctcttctgc catataagta tgtgcaatac ctgtcgtaca agctgtcaca gcaacgataa
     2941 actcctgagc atttgtagga acaaaagcta cctctttctg atcagaagcc gcatcaaaga
     3001 cagcaatcac ttcgtctgga cttgttgcct ttcgcagttg atctgcaaag ccatccttta
     3061 ataggtattg ggataattcg gctaaggccg ctaagtgagt atcatttgcc ccttgaggtg
     3121 ctgcaatcat aaagaacaga tcagttggct gaccgtctaa ggatttgtaa tcaacgccct
     3181 tgttagattt tgcaaagagc actgctggct ggtcaacaac aacatttttt gaatgcggca
     3241 tagcaatgcc atcgccaaga cctgttgagg tttgctcctc gcgagctaag atactctttt
     3301 taaacacatc aaagtcatgt acaatcccat gctctactag ttctgtaatc atttcatcaa
     3361 ttgcagcctc ttttgaaaca gcctgcaaat caagaatcat gatgtctttt cttaataaat
     3421 cctgtatttt catcgaacct ctacctcaac ctcattatat gtttttttaa tatcatcaat
     3481 tgctgctaaa tcatctgaaa aagcagttgc tgttccgcag gccactcccc attttagagc
     3541 ctctagcgga ctatgacttt tgacaaaggc acctgtaaag cctgccacca tcgaatcacc
     3601 agctccaaca gaattcttca cctgcccttt aataggctta gcaaaataag ttgcttcctg
     3661 agtgaccagc aaggcaccat caccagccat cgaaacgata acatgctgcg ctcccatgtc
     3721 aaggacctta cgagcatatg tttcaacgtc atctagccca tttaagctga cgttaaaaat
     3781 agcttctagc tcatggttat taggctttac gagcaatggg tgatacgcca atgcatctag
     3841 caaggtctgt ccttcaaaat cacagaccac ctgtgcccca gcttgtctga ccaatgggat
     3901 caagtcctta tagacatcat tgcctagact tgaaggcgct gagcctgcaa aaacaacaat
     3961 gtcctctgct gacacatttg ccaatatagc ctttaaatga tccaattgct gctttgaaat
     4021 cactggtcca aggccattaa tctctgtctc ctctgctgat ttgatcttaa cattgatccg
     4081 cgtatcctga tcaaccgtta caaagtcagt attgatgctc tcagcagcta gactttcctt
     4141 aataaaacgc ccagtgaagc cgcctaaaaa gccagtcgct gtattatcaa tgcctaatcg
     4201 ctgtagaatg cgactaacat taatcccctt tcctcctgca aatgtatcgt cactgaccat
     4261 gcggttaacc gctccaatat ctaattggtc tattctgaca ataaagtcta tagaaggatt
     4321 taaggttact gtgtaaatca tagtgcaatt accttcgctt tttccttgat tttcttcagc
     4381 attactgtcg aagatttctc tgtaatgatt tcaaccctat caattggagc aaccttgaca
     4441 aaggaaacat gaccaagctt tgttgcatca gctaatacat aggtgatttt agcattggca
     4501 atgacagctt ttttaataac agcctcctcc atatccggag tggttaaaaa tgcctcatcg
     4561 ataccattga taccaagaaa agccttatca aaattcattt gcctaatttg ctccaaggca
     4621 acatgaccga tgcttgcgtc tgttgtctgc ttgacatagc caccaataat aatggtcttg
     4681 atcgccatat caaccagtct agtcgcatga tgaatagaat tagtcactac tgttactttt
     4741 tttaattgca aaaaaggaag gagaaattcg gttgttgtcc cagcatcaat aaagatgaca
     4801 tcattatcaa aaaccagctc tgctgccttt tgagcgatga tttcttttat ttgactgttt
     4861 ttgacagatt tttcctgatt agataattcc tcttgtaagg aatgaaaaag ctcggcacct
     4921 ccatgcactc gatgaagctt gccctcacgc tccagctcat ctaaatctct acgaacagtt
     4981 gattctgacg agcttaacag ctgcattaaa tcctctagcg caacgtaatt ctcagctgtg
     5041 atttttgcca taatgagctg ttttcgtttt gattttaaga taaaaccacc cctttgtctg
     5101 aaatcgttta cagctctatt atactacact ttattccaaa gtcaagcact atcttttaaa
     5161 aacattcaaa ttcaatctta gacctctatt gccttaacaa taactgccaa ttgatcagtc
     5221 attgtccccg tcaatacctg tagactaatg attaacgact tttttattaa ctagagccca
     5281 aaaagcgctc acctgttgca aaagtctgaa acacaatagt ctcttacaaa tcaaaaagca
     5341 acggatttac tgtcgttgct tcataatgag agtctaggac aaagtctttt cagccaacaa
     5401 gacaaaacga gagagtcacc tattgtgagc ctctcgtttt attgtactga gaaattgttt
     5461 tatcccagac tccttatgtc taaacctatt tgatcttcaa aatattctct ttggcatgga
     5521 ctagctgtgt aatcaagcgg caataagggg tatcgatacc aagcttttca cccttggtat
     5581 ttaccgcacc gttgataaag tcaatttcag tcaagcggtg attttgaaca agatcctgat
     5641 gcattgatgg gtagtgatga gcagccttca ctgaggtttc catcacatag gctgtgattt
     5701 cctcttcatt aagctccacc ccctcagcac gaccaacaat aacaaactca tgaatgattt
     5761 ctttaaccat gtttaaacca tcttcgctgg caaataactc accaatcgtg caatcaagta
     5821 gggcacaggt tgagttcatt gtaccattga cacaggcttt tctccaaata tttggaacaa
     5881 cattatcatc ataagttgca ttcaattgag cgtcatttag caagtcagca atctgatgtc
     5941 ctgcctcttg gtttgctgga tccatgcttt gtagattaag cgcaccaact ccttgtaagt
     6001 gtacctgacc aggtccctca agacccgctg tccaaacggt aacacccatt aaaatattat
     6061 gctctggaat atagtgacga atcacatctt cgtgtccaag accatttaat aggcaaagta
     6121 ccttggtttc agggccaata atacctttaa tatcagtcag catttgtggc agctgcatgg
     6181 ctttggtaaa caaaatgata aggtcagctt ccttagtagc ctctgtcggc ttcatgatag
     6241 gaagctttac ggtttcctct acatcgcctg aaatcttcaa gccattctct ttgatcgctt
     6301 gaagatgtgc ttcccaatta tccagtaaaa taacgtcatt gtttgttttt gaaatttggt
     6361 aaccaaatcg acagcccata gctcctgagc ctgcaatata aactaacatg ctttttcctc
     6421 ttatccttca aatacaaaaa tatcttcttt ataaagcttt aaaatatcct tacaaagctt
     6481 atgtgccaca aaagcaactc caaatggaat gaccaaccaa gcaatgataa tgatcacaat
     6541 attgctgcca ccggcaagtg aagcaatagg accaactgca ccaacaagac caaagccaga
     6601 tgaggctggt gttccaatca gattaaacat tggaacggtt aaagagctaa caatagctgt
     6661 catcatcatt ggaatagcca taactgggta ttttaagaag tttggcatca tcattttcat
     6721 agcgccaagg gcaatggcaa ttggaacacc tgatttgtta acctttaacg ttgcccacac
     6781 aagaacagcg gttgttgaag caatacccat tgaggccgca ccagctgcca taccatttaa
     6841 gccgatagct aaaccaatcg caaccgttga gatcggactc acaatcaaaa gagcaaaggc
     6901 aatggcaatc aaaatagaca tcagaattgg ctgaagcgtt gtaaatgaat taatgccttg
     6961 gccaatcagg gtcgtcacat aagaaacgta aggaagcagc ttccagccaa tgtaacccac
     7021 acctgttcca ataataattg gcaacaaaat aatggttaga gacccaaatt tatcaccaaa
     7081 ccacttcact gctaaaacgg caagcgcagc tgtgatcatc atattaatca gatcaccaat
     7141 gccctttagc tggaaggtcc cagtggcaac acctttttgg ataacctctg tataagccca
     7201 agctccagaa ccgatataag ctgccccgcc gacagccagc tgctgcattg ggttaaattt
     7261 gaactgctgt ccaatcaaaa aaccagccat aactggcgta aagaattgga aaacctggac
     7321 gatatgtaaa aattcagctg ctacagtatt tggcaaaagc ggctttaaaa acgtcgctaa
     7381 aatagcattc ggaataagtg caactacaat cgcaattgct gtaccagcta agaccttatt
     7441 cataaacgag ctaaaggtct ctttatttgt tgttgtcatt tcatgacctc tcttaatatt
     7501 atagtgtgaa aaacatcacg aaagtattct aacataaaaa gagcattttg tcacagctat
     7561 tttaattttt atcaatacgt acagaatatt caattaaatg tcatataata ttaatcaatc
     7621 aaggctgttg aatgaacagg tctattatct ctatcaggat aaatatactt aatcgcttgg
     7681 ttgacagcaa tcggtgcctc accaaagcca gtggcaatca aatcaaccct gccttcataa
     7741 gctgctgcgt caccgatcgc aaaaatccct tcctgacttg tttgaaagag gggagagaca
     7801 agaagacttg agcgcttata atctagattc caatgcttta ggtttttatt agatgtagaa
     7861 aagccaaagc taacaatcag gctgtctagc tcaagcgtta tctcctcttc tgactttacc
     7921 ttttgaatag tcattttgtt gacaaagcca ttttctcctt cgagggcaag gggaacaaag
     7981 ggggtaaggg tagtaacatg agagtttttt aacaattcta cgctatgctc atgagcccta
     8041 aaggcgtctc gccggtgcac aagggtaaca ctcttagcga ggccatctaa ggctaaagcc
     8101 cagtccacag cagaatctcc accaccgcag atcacaaccc tcttaccagc aaactgattc
     8161 aagctgtgaa cattataaaa gagattatga tcagcaaata actgctcatt gtctaagccc
     8221 aaggttctag gcgcaaaggc tccattgcca caagcaacaa taatggcctt agaataatgt
     8281 ctggccttgc ttgtttgaat aacaaagttc ccatcagcct tctcaaaaga caggacctct
     8341 tctttcaggc atactgctat gcgatcgtca aatctgctta gctgctcaat aagcttttgt
     8401 gttagttccg ctccagtcag ggccggataa gctggaatat catagataac cttttcagga
     8461 taaagaacag ccggctgtcc tcctagctct gacaggcttt caataatctt aaccgtcatg
     8521 ccgcgcaggc ctgcataaaa ggctgcaaat aagcctaccg gacctccacc aatgatggta
     8581 atgtcatata ttttttcttg cactagttct ctccttcact tagccccgat ttgattttat
     8641 caaaaatcct tttttcctca tcagaaaaat cataagtctc taataaatct ggtcttctca
     8701 aataggtctt ctttaggctt tgctccatac gccagagacg aatatgctca tgatggccac
     8761 tcattaggac atcaggcacc ttcatgccac gataatcata tggccttgta tactgtgggt
     8821 actccaagag cccagatgag aaggaatcct cttgatgact ggcttgcttt ccaagcacat
     8881 taggaatcag tctcactgtt gcatcaatca ttgtcatagc agccagctca ccaccagtta
     8941 agacaaaatc tcccagagat atttcatcgg taacaagtgt cttaatgcgt tcgtcatagc
     9001 cttcgtaatg cccacaaata aaaattaact cttcctcaag agctaattct tcagcataag
     9061 actgatgaaa gggttttcca gcaggatcca gtaaaatcac tcgaggcttt gtagcctgaa
     9121 tgctatccat ggtatcaaaa ataggctgcg ctctcagcag catgccctgc ccaccaccat
     9181 atggctcatc atcaacatgc ctagctttct ccgcatggtc acgaaaattg tggtaatgaa
     9241 tatctaaaag ccccttttcc ttagcctttc caacaatgga gtgctccaaa ggagcaaaca
     9301 tttccgggaa aagggttaaa atatcaatct tcatcatcta agccttccat aatttcaacg
     9361 tctacccgat gcttttcgat atcaacacaa agaacaaccg atgggatata aggaagcaac
     9421 aggtcacgct tgctttgccg tttgaccacc caaacatcat ttgcaccagg ctgtaaaatt
     9481 tccttaatct ctcctactag ctggtccttt tcatacacct ccagaccaat aatctggtga
     9541 tagtaaaatt ctccctcagc tagcttaccc tgattctctt tagcaatctt aagactgtag
     9601 cccttaaatt gctcaatagc attgatgtga tacattccct taaacttgat aatgtcaaac
     9661 tgcttatgct tgcgatgact cgcaatctca acctcctgca caaaacgatc cttgtcgtca
     9721 aacagggcta gtctagcacc tttttgaaat cgttcctcag taaagtcact cacagacagc
     9781 acgcgcattt ctccttgcaa gccttgagta ttgacaatct tcccaacgct aaaatattcc
     9841 atccttactc ctaatcatct tagactctat agcttgatag acctctattt tttcatgaca
     9901 acacgacatg agtatcatca tcctaagcac tctagcctat cgttaaagct ccccttattg
     9961 taacatgttc tgccttattt tgcacttctc tttcaaaaaa ttaatctccc agttatagca
    10021 gctaagccta gcaagcaaag cccttgatgc taaagaatcc tgatccccct ataattaaca
    10081 aatcatcatg acttgccttg cccaagctca gtcaagtgaa tgaaaaatct gctaaacaat
    10141 agccttgcgc ctcgctgaca agcatcaaaa aaacactcct gctggcaatc tgaactgccc
    10201 cccaattgtt agattttatg tccaactttt gggggtcagt acaatctagt aaactagaat
    10261 caggagtgtt tcattatagc ccaacaagca aaaggaatac ttggtaaaag caaagctgac
    10321 ttgcattgag aagattaaaa ccattcaatc tgtcacaata attatggaaa cattgggaat
    10381 ttaaaaacaa gtatcagctg ctatcaacct gtggggaaat agtctaccta tgcctatcgg
    10441 gccatccatc ataggtcctc tcaagaaatg atgagagcct catcaaccag ctatcatcgc
    10501 cttaaaggag aatgacgaat gttatcgtag gtgtcccaag aaatactaca aaagaaactc
    10561 attttgatct taatgctcta aagggcttga ccttacgtca actgataaag ctctacttca
    10621 tagcatcgtt ttgctttgca gcttttctat acctcatgtc taataaaaga cataagcttg
    10681 ccgataagaa cattacccca acatagaaga atagattggt ctcatcgcca gtctttagta
    10741 agatggtatt ttgatgcttc atcggtttgg tagctgttga aacatgcgga cacttggttt
    10801 catttgtcgt cgatggtatt gtcggacgac ttggcttagt gttattaggc ttatgattgc
    10861 cttcactact gcttaccttt ttcttccact gtgcaaacaa ttcattagga aacggcaggt
    10921 cattatctac cctaatgtca tcacctacct tttttaacct cctgctcgat ctcttgttgc
    10981 atacaaaatg ttatacagat acttctgtca gatagagttc ttgcttttgt ctcttgactt
    11041 ggtgattcaa aacacaaaaa aagcctgcta gatagaacta gcaaggcttt aagattagtc
    11101 ttgttcaaaa tagaacttat ttttcatcaa tgactaatcg aacctttttt cctaaagttg
    11161 gcaccgaata gacaatcgat cttatcgctg tgatggtacg acctttcttt ccgataacac
    11221 gaccgatgtc ttgagcatcc aagtcaagat ggtactctaa aaaatccgga gtatcttcaa
    11281 ttttaatagt aagcttatct ggttgtgaaa tcaagggctt cacaatagcg ataatgagat
    11341 tttcaatggt atccataggc ttttattact tagaaaattt ttgatcgtgg aatttagcca
    11401 taaccccagc tttagataga aggctacgaa ctgtatcaga aggttgtgca ccttttccta
    11461 gccaatcaag aacacgatct tctttaagag ttacttgatt ttcagctaca agtgggttgt
    11521 aggttccaac tgtttcgatg aaacgaccat cacgtggtgc acgtgaatct gcaacgttga
    11581 tacggtagaa aggttttttc ttagaaccca tacgagttaa acggattttt actgccattt
    11641 taatatgtct cttttcttta aatgataata gtcaagaaat gtagtcctgc tcatttctca
    11701 cctaactagt atactttact tttgattatg tgtcaagttt ttttcttgac acttttttat
    11761 gatcataata ctactcaaca tcttcaatca gctaagctgc ttagatgaca tcaaacagca
    11821 ggcagctgct cttataagag catacaactc caaactaacc tactctagtg atccttagcc
    11881 gtcaataatg ggatcaggca agcataactc cccgtcaaag gagcggtttg tttcacagca
    11941 aaaaggcgaa ataaactgac aatcacatca aaaaggacga gcccctaaac atgcaggagc
    12001 tcgtcctttt accaatatga cttagtctct ccttgctttt aaggctaggg tattagctaa
    12061 gcgttacact aataatgcat caaaatatgc ttaagaaact ctccaccata aatccaaaaa
    12121 taactgaagg tcaaaattga aatgggtcta caaattagga taatcagtaa aaagcgcttg
    12181 taggtcatct gactcaatcc agtaatcata ataagagcat cggcaggggc taagggggaa
    12241 atcatattga gaataaagaa acgctcaaat aatttcgttg atagcttctt ttcataaaac
    12301 tgtagctgct ccatacttaa aaacagtaag ataaagggct ttccgtatct cctcaccaac
    12361 tgaaacaaaa tagaagatcc aatgcagata ccaaacacat ttaacataaa gcctaatata
    12421 ggaccaaagg ctagaaagcc aacgactgtt gtcacaccac caggaatgat aggaacaact
    12481 acctgcacaa tttgcaagat aaaaaagcaa atggcaccga taaggagatg atccttgatt
    12541 aaatgggcta aagcctttgg attattaata atatctagct gcctaataag gtagacaaca
    12601 agcatgacgg agaacagaat tgataggcca ccaagaatct taaacagctt ctttaacaac
    12661 gaatgtgaaa caccaaagct actcatagcg caaagcctct atcggatcaa gcttgcttgc
    12721 tttgtttgct ggcagcaatc caaaaataat accaattgat gccgaaaaga taatagctac
    12781 agccgcaaca tctaaggaaa cagctgctcc ctttaattgc atcgcatttc ctagcacacc
    12841 tacacacatc tgtgctagca gcagccctaa aagaccgcca attaacgtca acaccactga
    12901 ttcaatcaaa aattggctaa gtatcttcaa gcgcgttgct cccaaggctt ttcgcaagcc
    12961 aatttcacgt gtacgctctg ttacagatac cagcatgatg ttcataacac caataccacc
    13021 cacaagaagg gaaattcctg caatggaccc aacaactgtg gtcatgatac taaattgtgc
    13081 gttaatgtca ttgataattt ggctattgtc aggaacagcg tactcgccct ccttaacatg
    13141 agacagtgtg gtcagcatag cagctgcttg atttcctaat tcaaggcttc gcttaacgtc
    13201 gccaatataa agataaacag agccaatttc cttgacatga aattctgaag ccacctgggt
    13261 attggccata atggctcctc cagaaatccc accagcaaac gaaacaacct cctgatcagt
    13321 cttgtaaaca cctactacaa ggtagtcctt actatctaga ctaaccacct tatttagagc
    13381 ttgttcataa ttgcctttgc caaataattc gtcagccaag acagtatcta ataggataat
    13441 gcgagaaaaa tttttataat ccttgctatt tagcgtccta cctgcaacaa tatcatattt
    13501 tttgacttta aaataatcct gactaacccc agtgatggcc acattgtcca tcttcttttt
    13561 ctcaaaggaa atggtagagg ttgaattatt ggtatagtaa taagaatcta ccccatcaat
    13621 tgctttgaca atctgctcta gccattcagg cttgacctct tgctcatttt catgcgctgc
    13681 aaaggccgcg taagggttgt cctcatctcc ttttgccttg aaataaagct gaacctcttt
    13741 ttggtcattt gaaaaggaat ccgtaaccct ctttgtcatg gcagcaccaa gccccatgat
    13801 aatcacaaca gcagctacac cgataataat tcccagcatg gtaagaatcg aacgcagctt
    13861 gtgcccccag attgaactaa gagcaaattt ccaattttcc atcacttttc ctcctagtca
    13921 atcctgacac tttctgttgt atcagctgtg atttcaccat cacgaataac aatttttcga
    13981 gtggcaaagt ccgcaatctc tggctcatga gtaaccataa taatagtttt gccttcctta
    14041 ttcagctccg tcaaaagcct cataatctgc tcaccagtct ttgtatctag ggcaccagtc
    14101 ggctcatcag ctaagataat agacgggtta ttaaccaagg ctcttgcaat ggcaaccctt
    14161 tgcttttgac cacctgataa ctctgatggc aaatgcttca ttcgcatacc aagctcaacc
    14221 ttttccaaaa attgcttagc caattcacga cgctttgata ctccaactcc agcataaatc
    14281 aagggaagct caacattttg cagggcattt agctttgcta gtaaaaagaa ctgctgaaag
    14341 acaaagccaa tctcttcgtt tctcacctga gcaagctttc gatcatttag gatctcaacc
    14401 tgtgtgccat tgagacgata atcacctgag gttggtctat ctaataagcc gatgatattc
    14461 atcagggttg atttccctga gccagaaggc cccataatag cgacaaattc accctcatat
    14521 acagtcaaat ccacgccttt taggacctgt agctcctgat caccattttg atagctttta
    14581 acaatgcttt ttaattgtat taattctttt ttctcatctg gcactactta atcacctcgg
    14641 attctttact gcttttttta gaatcttttg atgcctttgt gtctgcggaa ataacgtctt
    14701 ctagcttttc accctctttg atgttcttat cagggttagc aatgacaata tctcccacct
    14761 ttagacctgc acttacttct tgtctttcag catcagcatt gcctagggtt acttcaacct
    14821 ttttagcctt tgcagttgag tcatcataga cccagacaaa atgcttcttg cctttgttaa
    14881 cgatagcagt aactggtact aaggcatgct ttgcttcgtt gataacctca acagacaccg
    14941 taaagccttg ctttagctgg ttaagcggac tcgtgatatc aattttgtag tcataggtcg
    15001 caccagttga gcttgatgag cctgagcctc ctgcagttga accacctgca ttggcatcgg
    15061 ttgggtagtt tgacacataa gaaatctttc cggtccactc ttgatcagca tagacctttg
    15121 atttaatctt cacagcttgt ccaaccttaa tattggctaa atcatactct gttagggtcc
    15181 ctttgacctg taacttgcct tcggttgcga catgaaccaa ggtttgactg ttttttgaag
    15241 acgggtcaat atcattatta acctctacaa ctgtccctga aacaccactg acaactactg
    15301 tttcatttaa ggcctgctgt gctttattga cctctgcttg agcatcagca taggaatcat
    15361 ttaaatcctg caattgctga gcatagctag cattttgctg ggctgagggc tgaatggttg
    15421 tggtggtttc ttgccctgtc tcctcgtcct tgcttgtctc agtagttgct gctggaacac
    15481 catacgtttt taaatgatta atctgacgcc caattttatt gagattgcga acagcggtgt
    15541 cataagctgc ctgtggtaca gttgtattgt actgtactaa ctgctggcct tgtgtgacct
    15601 gatctcctac cttaaccgta acggtagcgt ctgagccttt gctagcatca aaataaacat
    15661 attcttctga aagagcttta acagtaccag agagtaaggt tgaagaggct attgtccctt
    15721 ctgttacatt taccgcagaa taaggtagct tgatattttg atcagagata gtatcttgct
    15781 gttgcttcca caatactcca ccgataacga ctacagttag tgcaactgca cctgcgataa
    15841 tgcctttggt tttcgttgat aactttatct ttcctctttt agacatttct gtcctcccct
    15901 tttgtactat ttttgtaaga caagtatatg atgtttttaa aaacttgtca agaatttctt
    15961 ggataagctt aataaagcag cctcttcatc atgtagatga caactctatt ataatggttt
    16021 ttcaagctgt actagcttac acttttgtaa tattaaaaag aggcaaagac aaaaagagtt
    16081 gtcctttaac tttattacac agtctcattc attaaaaagc gaacaagcct agttttcaaa
    16141 atctcagaaa actagacttg ttcgtttgtt tagacttttc tctcagtctc ttcatcaggt
    16201 ttaaatagct tctatactaa aggtacggct ttcaagaact ctcagcattg ctactgctgt
    16261 atccaatgct gtaaacagag gaactccttg ttcgattgct gagcttctga tcatctgccc
    16321 gtccttatca gtcactcgtt ttgttcctac ggtattaata atagcttgaa tctgcccttt
    16381 tctcagtaag gctgggatat catgagcatt gtcgccaatt tttccaacta gctgtgaatc
    16441 tagcccttgg tcagcaaaga aagcagctgt gccttcggtt gccatgatct ggtagccaat
    16501 agcactaaag cgtctagcta agatcagagc ctccgactta tggtcatcag cgatggtaaa
    16561 aactattgtt ccatattccg gcatgtgcag atagctagct tcaaaggctt tgtaaagggc
    16621 tttttcaagt gttaaatcag agcccatgac ttcaccagtt gatttcatct caggccctaa
    16681 aaggctatcc accttagcga gctttgcaaa tgaaaaaacc ggtgccttga tatgaacaag
    16741 cgagctttca ggataaaggc catcttgata acctaagtct tttaaggtct gacccagaat
    16801 aagcttcgta gcgacttgtg ccattggaat attggttact tttgataaaa atggcactgt
    16861 ccgactggca cgaggattga cctcaatgac atagacctgc tcattttgga tcacaaattg
    16921 gatattcatc atgccaatac agtttagccc tatagcaaga cgcttagtgt aatcaacaat
    16981 cttgtcttga acctgtttag ataggtgctg cggcgggtac acagccattg aatctcctga
    17041 atgcactcct gctctttcga tatgctccat gatccctggg attaagactg attgaccgtc
    17101 agagattgca tctacctcgc attccttacc aaggatataa gaatctatta aaacaggatg
    17161 ctcaggacta gccttgacag ctgttttcat gtaggagcgt aaatcgtttt cattttcaac
    17221 aatttccatt gctcggccac caagaacata agagggtctg accaataccg gaaagccaat
    17281 ggcacgcgct gcctctaagg cctctgcctc attggtggct gttttcccag gaggctgagg
    17341 gatccccagc tccttcaagg ctttttcaaa aagctcccta tcctcagcac aatctaagtc
    17401 ctctagctgt gtgcctaaaa taggaactcc ggccttggtt aactgctctg ctagattaat
    17461 agcagtttgt ccaccaaact gtaggattac tccctttggc tgctctaatt caataacgtt
    17521 catgacctct tcaaaggtta agggttcaaa ataaagcttg tctgatatcg aaaaatctgt
    17581 tgacactgtt tcaggatttg aattcatgat aatggcttca tagcccgcag cctgaatagc
    17641 cttgacagaa tgtacggttg cataatcaaa ctcaactccc tgaccgatgc ggataggacc
    17701 agagccaagg acgataacag attctttctc ggatttgatt gattcgtttt cccactcata
    17761 ggtcgagtaa aaataaggcg tttgtgagtc aaattcagct gcacaggtat caaccatctt
    17821 ataaactggc aagacacgat aggctcgcct taaccgtcta atacttgcag catcagtttg
    17881 ccaaagctct gcaatttttt ggtctgaaaa accatatcgc ttggcttcta tcagcaaatc
    17941 gatatcaact ggctttttaa taaggtcttg ctccagttct acgatatgac gtaatttatc
    18001 caaaaagaat aaatcaatct tggttaagcc agctagctct tcaatactat agccacgacg
    18061 aagggcctca gaaagataga atagacgatc gtcctgtgct cttacaatgt gagcaaccag
    18121 ctcatgatca ctgatagtat ctagaccctt cagttcgtta tggtgtactc caatttccaa
    18181 cgagcgacaa gcctttaaga gacattcctc aatacggcgt ccaatagcca taacctcacc
    18241 agttgctttc atctgggttc ctagacgacg ctccccccgc tcaaacttgt caaatggaaa
    18301 gcgtggcagc ttggcaacca cataatcaag agctggttca aacatggcat aggtggttcc
    18361 tgtgaccgga ttaagcatgt catcaagcct taagccaact gcaattttag cagctatttt
    18421 agcgattgga taaccagttg cctttgaagc cagtgctgat gagcgagata cccgcggatt
    18481 aacctcaatc acataatagc tgaagctatt gggatcaagt gccagctgaa cattacagcc
    18541 tccttcaatc ttaagggcac gaataattct caagctagca tcacgaagca gctgattctc
    18601 aacatctgat agggtttgtg tcggggcaaa aacgattgaa tctccagtat gtatccctac
    18661 tgggtcaaaa ttttccatac tgcaaacaac cagcgcgtta tcagcagcat cacgcatgac
    18721 ctcatattca atctctttaa agccggcaat ggagcgttca atcagacact gggtgacagg
    18781 agatagcttc aggccattct ccacaatatc tcgcaagacc tcttcattgg agcaaatacc
    18841 acctccagtg cctcccagag taaaggcggg gcggacaata acagggtagc caatggcatt
    18901 tgcaaagccg atagccgcct ctactgtcgt cacaatctct gattctggaa taggctctcc
    18961 caactctttc attaattgct taaataaatc acgatcctct gcctgatcaa tagcagataa
    19021 ggttgttcca agcagctcca ctcctaattc ttgtaaaata ccagccttag acagttccat
    19081 cgccatgtta agaccggtct gcccacctaa ggtcggcagc aaggcgtctg gtctttcctt
    19141 tcttaagata cgactaacaa atgccaacgt caggggctcg atataaacct tatctgcaac
    19201 ctctttgtct gtcataattg tcgcagggtt agaattaacc agaacaacct gatagccctc
    19261 ttcctttaag gctaaacaag cctgtgttcc tgcgtaatca aattcagctg cctgcccaat
    19321 aacaatagga ccagacccta tcaccatgat ttttttaata tctgtacgtt ttgccataat
    19381 atctggtaca aaaggcctta acaatccgaa taaaataatg caagcaccta acattaaagc
    19441 atcacaatct attttttact aggatttgta cctgtactca gctgcagcaa gccctttgta
    19501 cctactcctt tcattatttg ccgtctcaca gggcggcatt aaataaaaca cttaacagtc
    19561 tgtcacatga gacgatgagt acaagatcaa gtaaccctta gctcagcaag tatagatgac
    19621 ttaattgata tagtcttttt acttctaaag agggcgatct tgccagcaaa tactagtcat
    19681 aacccgcggc agagcgatca tttcccacta gtctatctgc tgcctgactc aagctgtttc
    19741 atgacagctg atcaagcctt tggtgcttgc tttttgatct gctagcacac ttgattaaca
    19801 tttgccttgc tgctctagct gccaggcgtc aatcatatct aaaaattcat caaatagata
    19861 gctagcgtca tgagggcctg gtgcagcgtc tgggtgaaac tgcacagaaa aggcgggaac
    19921 atgtcgatgt ctcacccctt caacagtttt gtcattaatc tcctcgtgcg taaccatcaa
    19981 gcagtctggc aagctgtcgc gctcaacagc ataaccatga ttttgactag taaaatcaat
    20041 acgtccggtc gctatttctc tgacagcatg attaaagcca cgatgtccaa aaggcatttt
    20101 aaaggtctta gcgccattag ctaagctaag cagctgatgg cccatacaaa tgccaaaaat
    20161 tggaattttt ccttgaacac cacgaatcat ctccaaggcc tccggcaaat cctctggatt
    20221 acctggacca tttgatagca ttagaccatc tgggttgagc tgtagaatct cttctgctgt
    20281 gatatcaaag gggactattg tcatctgaca ttgccttttg gataattctc ttaaaatgga
    20341 atgcttcaag ccaaagtcca ccaaaacaat atttttccca acacccggag cgggataggc
    20401 agtcttagtt gacacctgct caataccatt agtcggaagc acagttgcac gcagctgatc
    20461 ctttaggtgt tcaagcgtat caccatcatc tgccattgtt gccttcatcg taccatgctg
    20521 acgaatgatt ttggtcaacg ctctggtatc aattcctgaa atgcctggaa tccccttatg
    20581 ctttaaaaac tcgtccaagg tcatttgctg acgccaattg ctagctatcc tgcttacttc
    20641 agagacaatg acccctttgc aagttggggc aatggactca taatcatcac gattaatacc
    20701 ataattacca acaaggggat aggtaaatac taagagctgc ccgttatagg actggtctgt
    20761 gattgactcc tggtagcctg tcattcctgt attaaagaca atctcgccag tgacatcaat
    20821 atctgcacca aagggctttc cttcaaaaat ggtgccatcc tctaagataa gtaaccgttt
    20881 tgccatttta accccctcta acatgccttt agaccttatc gtttctgcca ttaaggatcg
    20941 cttcgataat ggccatacgg acaaatacac cattagccat ttgagctact attcttgcct
    21001 ttggagcctc tactaaatgg tcagcaatct caacatcgcg attaaccggt gccgggtgca
    21061 taataatcgc agagtccttt aaccgcctgt agcgctcctc agttagacca aactgtctat
    21121 gataatcttc cttggaaaag ctttgactac catcatggcg ctcatgctgc accctaagca
    21181 gcatcaacac atctaattga tcaataatgt gatcaatcgc catgtacctt ccatagctgt
    21241 caaattcaga cgagtaccat tgctcaggac catagaaata aagctctgct ccaagccgct
    21301 ttagaatctg catgtttgat ttagccacac gagaatgtgt caaatcccct gcaatagcaa
    21361 tcttcaggcc atcaaaatga ccaaattctt cataaatagt tagcaaatca agcaagcatt
    21421 gactagggtg ctgacctgat ccatcacctc cattaacgat agaggcagta atcgttggac
    21481 tgtcaataag ctgctgatag taatcatctt ctgggtgacg aatcacgcag atttctgttc
    21541 ctagagcact catggtaaga acagtatcat ataaggtttc ccctttattg acagcacttg
    21601 tatcagcgtt aaaatcaagg actctaagac caagcttgtt ctcagcaacc tcaaaggatt
    21661 tatgggttct tgttgaattt tcaaagaata aattagctgc aaagtgccta ctgttatctt
    21721 taatagctac cttacctgcc ttgtattcag agccacgact aataagtcct aaaacctctt
    21781 catttgttaa atgctccatt gacaccaaat gcttaagcgc aacacgatta tttacaactg
    21841 acatgattta tcccctttta ccaataatga aatgatgata acaattgaca acagctacac
    21901 actagttttc tggaagaagc tgatacaata taatgccaag aagcgttgaa aaagcaacac
    21961 ccgaaatctg aaggccattg atttgaagca tgaggcctcc aataccagaa accagaataa
    22021 cactagcaat caataggttt ttcttgttgt ccatatcaac cttagcttca atcaggattt
    22081 tcaagccact agaggctata accccaaaca gagcaatcga aatccctcca atcactggag
    22141 taggaataga ctgaataagt gctgatacct taccaacaaa gcttaacaaa ccagcaatca
    22201 cagcggcacc tgcaataaca tagactgaga agattttatt gagggccatc acaccaatat
    22261 tttcaccata agatgttacc ggaggcgctc ctaaaaatcc agcaatcacc tgtgcaaggc
    22321 catcacccgt caaggttttt tccaagccag gatccttgaa ataatctctt ttagtcaggc
    22381 tattaagcac catgatatga ccgaaatgct ctgtcatggt gacaaaggca atcggggcca
    22441 tcgttaaaat agcactagga tacaaggtaa tgtcataggt taaaaagggg atagccacag
    22501 ctggaacact gagccattgg gccttagcaa cctgtgtaaa gtcaacaata gactgacccg
    22561 tcaccatacc aacaaggatc gcaaacaaat agccaaccaa taagcccaac aaaataggaa
    22621 tgatggcgac aatcccttta ccataaatgt taaagaaaat aatcgctaat aaggtgacaa
    22681 gaccaatcaa aaggtataac aggttatact ttccatcctt tagcatgaca tcactaactg
    22741 ctgttgaggc caagctaaga ccgatcacca taacaatggg accaaccaca actggaggta
    22801 agatcttatc gatccattca ttgccaatcg ccttcaccac cagtgctaca accagataaa
    22861 ccaggccacc tgtaatcgct ccctgtgcaa ctgcaccaat accatctgtt ttcattagca
    22921 tttgcatggc tgcaatataa gcaaagcttg agcccatata agcgggaatt ttaaatgttg
    22981 ttactgacaa atgcgccaga gtcccaagtc cacttgataa gagggcaact gacggatcaa
    23041 tcccaaccaa aattggaacc aaaacagttg ctccaaacat agcaaataaa tgctggaagg
    23101 acaagccaag caaaatccct gcctttggca cttcttctac atcataaatg acatctttca
    23161 cacaatcacc tctttcttat cccggatcaa caatactaat acgatcttga ccgtcaacct
    23221 caaccacctc aacgacaatc tcttctgtct tgcttgtggg aatattcttt ccaacataat
    23281 cggcccgaat tggtaattca cgatggcctc gatccaccaa aacagctagg ctaacacgtc
    23341 caggacgccc taagctaacc aaattgtcga tagctgcccg aatcgttctg ccggtataaa
    23401 gcacgtcatc tactaagata atatccttgc cggtaatatc taccggcatg ctggtggtgt
    23461 cctcttccac tctcatatca tctctaaagg gcttggtatc tagctctcca actgccaagt
    23521 gcaggctttc tagctgctct aatctttctt gaatacgacg agcaaggtaa acacctcttg
    23581 ttttaatccc tacaagcacc acattgtcta gttgcttgtt gcgctcaata atctcgtacg
    23641 taatccgcgt gatcgcacgc ttcatggtta gctcatcaac aattaccttt gatttcattc
    23701 aaagcctcct caaaaaattc aactaaaaaa atctccctgt taacaaggag attcagcaaa
    23761 acaggcacac agctagacat aactgtgcac ttttttattc agaacatgct ccttgccagc
    23821 ctcacaggac tgttttaaag gaatatttta ttttcattag tatagcaaaa tcacaagcca
    23881 aaaacaagga ttttctaaaa aataattcaa aatatataga gctatcacag caccaaggaa
    23941 aatgctacta aggtcatcag caatcctcca acacaattcc aaaaataggt cttaagacct
    24001 attgtatttg tatcaaaaca atagcacaat aatatcaaac acaaaggaga gcgtttatga
    24061 tgaatgatat aactagaaag attaaccata agcaactgat tcaaatcact accattctag
    24121 gcattattgt taccatcgtt attttgttct atctgcagca gcaccctaat ctttttgcag
    24181 ttggcggtcc ttttcagacc tatcttatgg aacttggtat cctagcaccc tgtttgttta
    24241 tactgcttca aatcattcaa gtggtttacc ctatcattcc tggaggcttg acctgtgttt
    24301 tagggcatgt agtctttggg ccgttttggg gatttcttta taatactcta ggtattttta
    24361 ttggttcgct gcttagcttt atgctcgcta gaaaatatgg tgaacagttt gctaaagcct
    24421 ttgtatcaga tgatacctat aacaaataca ttccttacct caataaaggc aagtactttg
    24481 aacgatttct cataacagcc tttattctcc ctggctttcc agatgatttt ctctgtatgg
    24541 tagctggact aagcagcatg tctatcaaaa catttaccag tattttcttg atatcaaagc
    24601 caattactct ttatatctac acccttcttg cttaccaagg catacaaatc gttggacagg
    24661 tattgcaatc ctaaaaaaag ctagtattaa gctatcaagc ctgattggaa tacagtattc
    24721 caatcaaaaa ggcgctcagc ttggtaccag ctttttatcc ttgtcttagt tgctccaaag
    24781 tcctttggaa gatttctggt ggctcaacag taaagaccag ctcctctcct gtcacagggt
    24841 gggttagtcc caatgtttgc gcatgaagaa actgcccctt gccagccaag gtcttacgag
    24901 gaccgtagag tggatctcct gcaagagggt gaccaatata agccatatga acgcgaattt
    24961 gatgcgttcg acctgtttcc aattgtaatt ccacgaaggt atagtggcca aagcgctcca
    25021 aaaccttaaa aagagtcaag gcttccttgc ccttagcagt tacggtctgt tttttacgat
    25081 ccttttcact gcggccaatc ggagcttcaa ttacacctcg atcctttggt aaattaccat
    25141 gaacaatggc cacatacttt cgtaaggatt tcttagcctt gagctcatca gctagtagct
    25201 ggtgggcctt atcggtcttg gcaaccatta aaagaccaga ggtatcctta tcaattctat
    25261 gcacaattcc tggacgaata acaccattaa tagaagacag gtctttgata tgatagagca
    25321 aggcattgac cagcgtccct gtagaatgcc ccgcagaagg gtgaacaacc attccctgag
    25381 gcttattaat aatggccaat acatcatctt ggtagacaat atctagtggt atatcctgag
    25441 cctgatagtc caagctgctt tcctctggga tatgatagct aatgcagtca cccacctgca
    25501 caatatactt ggccttctta ggtaagccat tgaccaatac ccttttttgc ttgatctgat
    25561 cattagcctg acttcttgat aatggggtca aatcagccaa ggccttatcc aagcgatggc
    25621 ctgattctgt tatcttaatt tccatagtcc tcttctttcc atagacaaat gaccagcagc
    25681 aaaacaccta tcgtcaaata ggaatctgcc acattaaaaa tagcaaaatt gatcacatct
    25741 aaatgaatca tatcaaccac ataggataac ctcaagcggt caataaaatt cccaagacct
    25801 ccagatataa tcagcaataa agagagctgt agccaaaagc tagcctttgg gtgcttcaac
    25861 acataataaa tggcatagcc aaccaccaaa acagttatga ttgtaaagaa ccactgctga
    25921 ttctgtagta tggaaaaagc agctcctcga ttttgaagat aggtcaagct caccaaacct
    25981 ggtataaagg gcttcacctg ccctagctca atatgtgtaa cagtccacca tttacttagc
    26041 tgatccagta tcattaagac aatggcagcc ataataaaac taattctttt caactaatcc
    26101 tattcctttc agcttaaaaa caagagatta ccttgatggc ttcaaaaaag caacaacagc
    26161 cagctgtctc tgtagcgtac tcaaccttaa agcctccaaa aactggtatt ctagtaacct
    26221 tttagtatca ttgatagtca accacacagc agctctagac ttgactttat atcaacaagt
    26281 ctcaccacag cagctcgctt aatccttatc cataccagag ctaagtccca ttgtctatag
    26341 cttgcttttc ttttcgatgt tcaaaataat cctgtaaaat ggtcacaaaa tgtaaagccg
    26401 cagcagatag gttcttatcc ctacgcttga cataaatcat tttatgctcc atatgatcac
    26461 gcaagggaat aaccttgatg ccattaacgc tttgctgatc taaaaatcca gaccctgttg
    26521 caaaggcagc tgtcctttcc aaaatgccat ttaaggttgc cctatctgac acagtgtata
    26581 tgtgaggact cttgcttgtg tcaataaaat tttctgaata ataaagatat tcttcttttt
    26641 cttgagtaaa gcgtaccgct ggcagccctt gcaaatcctc taagaaaagg gctttccttt
    26701 gagccaatgg atggtttttt gataggtaaa tatgggttgt aaaggatagc aattcaacat
    26761 aatccaaagc cagcttatcc attcgctgaa aaagcccctg acggttttgt gcattaagat
    26821 agataattcc aagctcacta tttccctgtg ccacctcatc taaaatttgc atagtcgttg
    26881 actcaaaaac tctaaaaacc ttatgcccag catgcttttg ggaaaatgct gttattaaag
    26941 ctggtaaaaa atcataatgc tgactcgcaa ttgaaaattc atttggctcc aaagccgatt
    27001 gagaaaactc cttttccagc gagtcaaagc acttaacaac ctctaaggcc ttttcataaa
    27061 ataaaagccc ctggctggtt aacacagttc ctgctgttgt cctacgaaag atctgaaagc
    27121 caagctctgt ctccaaatcc ttcactgaaa cagacaaact gggttgactg acaaatagct
    27181 ttgaagcagc ctcacgaaag gtaccattat ttgcaatagc aaccacatat cgtaattgtt
    27241 gaatattcat taatccactt cctaaatcta gtacccttca ttataccata aagccagcca
    27301 atgaaaaata aaggcgtcca tcttaaccat gccaaacgta tctacagata atcatgagat
    27361 agcattgact ttttcaatag tgtcttatca tatttagcta tagaaaacag ccttactata
    27421 agttatactt ttgaaagaag taagccttag atcacagaac atcacactga gattttttat
    27481 gcgcttatcc tgtctgtcca agaactgaga attggctaca tctagctaat aagccatttc
    27541 aggattttac tgtctaggag ttatttatag gcaactatta cagtaagata gtgtcacaat
    27601 acaaaaaagg ctatcccaaa gtacagaaca gccttatacc gtgccctttt aacacattat
    27661 tttgcgattg ggtatacaga aacttgtttc ttatcgcgtc ccttacgctc aaagcgtaca
    27721 acaccttcaa ccttagcaaa aagagtatca tctccgccac gaccaacgtt aacaccagga
    27781 taaatatgtg tgccgcgttg acggtaaagg attgaacctc ctgaaactgt ttgtccatca
    27841 gctgccttag cgccaagacg ttttgcttgt gaatcacgtc cgttagaagt tgaacctcca
    27901 ccttttttgt gggcgaagtg ttgtaggtta gaaagattaa gtttaatcat ttttatttcc
    27961 tctcgttgaa tttaattcat cacaggcttt tgaacatatt ctgataaatg ctctgccaaa
    28021 ttctccaagc caatcacaac agactcaaac agaatttgcc acacctgctc ttgttgctca
    28081 gtaaatccct caggctttgt tacccttagg aatccaccac catcgaccat ttctagtgct
    28141 ggctcaagac ctgtcatctg ttcaactgaa ttaacaagat tgaaggccaa aactgaaacc
    28201 gaagcacaaa ctacatcaaa gccgtactca ccgcttccag catgtcctgt gataagcatc
    28261 tcagtccagc cagctgcgtc ttttgttaac cgtactttaa tcatgtcaaa ctagaattat
    28321 gccttgatag cgttaatcac aactttagtg taaggctgac gatgaccttg cttacggtgg
    28381 ctaccttttt taggcttgta cttaaaggtt acaaccttct tttgttttcc ttgcttttca
    28441 acagttccaa cgacagtagc tccctcaaca actggagtac caacgacagt cttatcacca
    28501 cctacgagaa caacctcgtt aaaagtgatt tctgcgccag cttcagcgtc aattttctca
    28561 acgtagattg cttgacctac ttcaacttta acctgttttc caccagtttt gatgattgca
    28621 tatgtgctca tgatgcacct cctataagat ttttgatgag gtttccctct gtgaagactc
    28681 gcctagaatc gtgagagcca atctacttga aaacgatttt cgtgcggttg cacaggacgt
    28741 gcacttagtc aacgttacaa ttttaacatc aaatttgatt tttatcaaga aaaatatgct
    28801 tttatcttcc taaaatctta agctatacat aatcacagct atgtaaaggc tagcaatgct
    28861 ttaccatttt aggttaacca gggcattcat ttctttataa gcaatagctg ctttttcttg
    28921 cgtttcggga tcaatcttat cataatatct gccgcctttg ataaagtcct ccaaaaccat
    28981 ggtacgatag ctatatagct catagccttc actaccataa aggcccttag gcttagctaa
    29041 aaccattgtc gggtgagcct ttactgtttt tatttttgtt ttttgcccct tcttctcaaa
    29101 ggtaaggtcc attagcacgc cgcgctctgt ccaaatatca tcaacagtct ctaggcgttg
    29161 attggaaatg aaattaccca ttgaatagat aataaatttc ttttccttgt ccttaacaat
    29221 cgtctctgcc ggctctacga cgtgggggtg acctcctaag acaacatcag caccccagtc
    29281 aatcattttt cgataaagag ttttttgctc agctgttggc tctaaagcat actctgtgcc
    29341 catctgcggc ataacaatgg taatatcggc ctctttttca gcacgcaaga tgtctttttg
    29401 tatcttttcc tcattaaggt cagacaggtg cttgtcatac tcctcctgac tgagtgtcgc
    29461 ctccattcca ttatagccat atgaatagcc caatattgca atcttaatcc cattaacctt
    29521 tttaatgaga atgttctcct tagagcgatc ctgctcataa ataccaatgc tgtctatccc
    29581 catatcagca aaaacacgct tggtattgag agctccttct aatcttgagt ccaaaatatg
    29641 gttatgggcc aaatcaacca catcatagcc agtatgctta agcgcagcag caatagcctc
    29701 tggcgcatta aacaaaggat agccagctag aggatagtct ggactgatcg ttccctcata
    29761 gtctccaatg gccaaatcag cctgactaat ccaatccttc acatactcaa aatagggatt
    29821 aaaatcatag ctaccatcag cctttttagc actcatatag agaatatcat gaatcaaaat
    29881 atcaccattt gcgacaacac gcgctgtttg tgtcttttga ggtgtcttgc ttttcgtttg
    29941 tgtgcctttt tttgacatgc ctaataaatc aaaggccaac ccaaaaacaa gtatcaccac
    30001 aatcaaggta agcactgaaa gcatggtctt tttatactga aaatctttta gcaagcgtca
    30061 aacctccttt tttcctatta taccatgttg acacgacttt ttaataacaa atcccaaaga
    30121 aaaggctatg cccatttaag aagaatgcct tagacagcag catagactcg tattagctag
    30181 tcaaaaaact agattgctcc tctttggttg atgtcatata ctttgagcct aaatagcttt
    30241 caacaaagtc taatagttga ataatgtcat gcaaaatatg gtataatgaa acaaaatcaa
    30301 actagtcagg atagtcacat gaagcataac tctttcagcc gctcactatt actccccctt
    30361 ctcatctgtt ccttgtctgc ttgctcttct catacagaga aaaaagacca taccaaagac
    30421 gctactgcta tcaccgatac ccgaaaagca gagcatcagg acatcagggc aaatatggaa
    30481 aaggtcaagc tcgctaccgc tagcaccgac ttcaaaggtg gctcaagcct tgaggagcta
    30541 atcactattt ttggacagcc tagtcagcac gaagaaaaag cagctggtag tgttactctt
    30601 gactcctaca catggcagtt tgaccatgtc acggttaata ttaacctcta tgaaaacagc
    30661 agcattgtta aaactattgc taactttgct tttattagag acctgacctt atccttaaag
    30721 gactacaaca gcttgaaaaa gggcatgacc tatgatgagg tcaagcagct attgactgag
    30781 cctgataatt acagtcaagc caattccagt gaaaaagaaa ccattcaagc catttggatt
    30841 agtggcttaa aagctcagac acagggtgcc aatatagcac taacctttga aaacaaccag
    30901 ttgacagaaa tgtcacaggt tggtcttgaa gactagtttg tggataaccc caatcatatt
    30961 aatgatagaa aaaagcttga tatttaataa gatcaagctc aaacgataga ccaagtagct
    31021 gatgatcttg acagtaatgt gtaacaagct gagatactac tcactaggca gtatttacta
    31081 gcagccactg aatttccttt atgatgacag gcaaccacct tttttgtggt gacctatcaa
    31141 tagcaccata agctctcttt tgtcacatac cttgcttaac attattttac caggtatgtg
    31201 atgagctttt taggttgtct gatagtataa catctaaccc ctagttgatg atgtagataa
    31261 ggcaagagct gctaaggata gcaccataaa taagatccaa catagggtca tattatatag
    31321 tgccaagaac gaaaagataa agacacctac agggagcgat aaagagaaca gaagacctaa
    31381 aaagttattg ctttgggcta gcatatctga tgggagattt tccattaaaa gggcgtccag
    31441 cttgggtgtg gcttttccca taatataagc tgcaaaggct aagcataaaa cccctatgat
    31501 ggcaggtaat tgcagagcat tagagactcc taccagcaaa aatgctatgc cctgagtctg
    31561 tactagcttt gatattgaaa gccttgaaaa gtaatccttt ggtgttagat ttcccaacat
    31621 cgctccgata atcgtaacgg catcaacaat aactaaagac tgcccataat gaaaatgaaa
    31681 tagctgatga tccatcaaat aaaaatgata aatgctatta attgctcctc caatagcgtt
    31741 taaggtcaag atggataaga gtaacatcac aaaagagata tgatcaatct ttttaaaggt
    31801 ctctgtcatc cttgtataca tcaccttaaa ttgcttcatt aatgaaacac ctgcttcaga
    31861 agcttcaacg acatcatgcc ttagcttttg tcgattttta agaagcacaa cagatgacaa
    31921 taaaaaggaa atagcattta tcaaagcaac aaaggcataa ttgttgcctg atgtcgttag
    31981 cagccaaact cctaaagctt gtcctgcaat actagagagg tagccgataa attgagcaaa
    32041 agaataggcc tcatagagct tttctgattc aatatttttc tgcattatcg ggagacgtaa
    32101 gccatttttg taatcactta gaatatcaga aaccacattc aaaaagccca caaaggcaaa
    32161 taccaagaac gtctgatttg tcatcaacaa ggctacaagc gtaaataaaa gagattgtat
    32221 aaaaccaata acaataagat ttcttgtttt cctttttgtc ttatctgctt tgacgccaat
    32281 ccaaaaggta aacaccatag gaatgatggt gatgatattg gctataaaaa cagcaatatg
    32341 agaataaggt agcgtggttg cataaataat aaaaacaata ttgtaaatat aagagcctaa
    32401 agcacttaaa aagtttgaaa ctgtcagtgt tctaaaaacg acatttttaa tcaatcccct
    32461 catttactta cctgttgacg tcctttctta tgtcacctta ctttacttga ttgaatatac
    32521 ttacagcata tctaaattcg tactgtagtt ttatatggtg ttctgacatg attttgctac
    32581 taattagtaa ttcacaagcc ttttctaagt ataaagtatc gtttgttagt ctaaatactt
    32641 gtaaaagtgt catggctatc cccagcattc cgttccatag accactaaac tgagcaaatt
    32701 caactaataa cgactccgat aaattcttaa tatctttaat atatttatcg gagttaacgt
    32761 aaataagcaa ttgaacgatc ccagcagtcc catttgataa gtatggagat acagaatttt
    32821 ctgatattaa tacaccccga tttccatcgc tatcttcaac taagctttct agaataaaat
    32881 caattccttt ctcaataatt tcgttatcat aagaaattga agacagatag aacaatactc
    32941 cagctaaacc atttaaccct aaattaactt ctgattttaa ttgcatcaaa acttcatcgg
    33001 atttatccaa aatcttatta tatttagtaa ttagtgtgtc ttgtaaagaa ataatattaa
    33061 caagttcttg attccaatca tcagatattg caatattagt atttaattta taagtacatt
    33121 gaaaatgata agaatagatg tcgttcctga tcatattaat agcctcttcg atgtctgaat
    33181 tctcactcaa aagatactca ataagcttat aaatattaga atttatgccc ttttgtagta
    33241 at
//
LOCUS       DARYXZ010000024        31392 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYXZ010000024 DARYXZ010000000
VERSION     DARYXZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31392
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..174
                     /locus_tag="TV186_001006"
     CDS             <1..174
                     /locus_tag="TV186_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1532411.1"
                     /translation="EAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIA
                     AGTIAIPKRKEED"
     gene            complement(420..734)
                     /gene="trxA"
                     /locus_tag="TV186_001007"
     CDS             complement(420..734)
                     /gene="trxA"
                     /locus_tag="TV186_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL1532412.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            914..2233
                     /locus_tag="TV186_001008"
     CDS             914..2233
                     /locus_tag="TV186_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL1532413.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2573..4909)
                     /locus_tag="TV186_001009"
     CDS             complement(2573..4909)
                     /locus_tag="TV186_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL1532414.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IEIAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(4982..5527)
                     /locus_tag="TV186_001010"
     CDS             complement(4982..5527)
                     /locus_tag="TV186_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL1532415.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5527..5838)
                     /locus_tag="TV186_001011"
     CDS             complement(5527..5838)
                     /locus_tag="TV186_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532416.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            5956..6864
                     /locus_tag="TV186_001012"
     CDS             5956..6864
                     /locus_tag="TV186_001012"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL1532417.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            6889..7488
                     /gene="lepB"
                     /locus_tag="TV186_001013"
     CDS             6889..7488
                     /gene="lepB"
                     /locus_tag="TV186_001013"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1532418.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7717..10116
                     /locus_tag="TV186_001014"
     CDS             7717..10116
                     /locus_tag="TV186_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL1532419.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10212..10697
                     /locus_tag="TV186_001015"
     CDS             10212..10697
                     /locus_tag="TV186_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532420.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TV186_001016"
     CDS             complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TV186_001016"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL1532421.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12152..14476
                     /gene="pflB"
                     /locus_tag="TV186_001017"
     CDS             12152..14476
                     /gene="pflB"
                     /locus_tag="TV186_001017"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL1532422.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14782..15060
                     /locus_tag="TV186_001018"
     CDS             14782..15060
                     /locus_tag="TV186_001018"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532423.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15224..16165)
                     /locus_tag="TV186_001019"
     CDS             complement(15224..16165)
                     /locus_tag="TV186_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL1532424.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16162..16917)
                     /locus_tag="TV186_001020"
     CDS             complement(16162..16917)
                     /locus_tag="TV186_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL1532425.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17410..18258)
                     /locus_tag="TV186_001021"
     CDS             complement(17410..18258)
                     /locus_tag="TV186_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL1532426.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKGSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18360..18812)
                     /locus_tag="TV186_001022"
     CDS             complement(18360..18812)
                     /locus_tag="TV186_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1532427.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18832..20031)
                     /locus_tag="TV186_001023"
     CDS             complement(18832..20031)
                     /locus_tag="TV186_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1532428.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20200..20859
                     /locus_tag="TV186_001024"
     CDS             20200..20859
                     /locus_tag="TV186_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1532429.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            20880..23165
                     /locus_tag="TV186_001025"
     CDS             20880..23165
                     /locus_tag="TV186_001025"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL1532430.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23271..23663)
                     /locus_tag="TV186_001026"
     CDS             complement(23271..23663)
                     /locus_tag="TV186_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL1532431.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23817..24074)
                     /locus_tag="TV186_001027"
     CDS             complement(23817..24074)
                     /locus_tag="TV186_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1532432.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24253..24627
                     /locus_tag="TV186_001028"
                     /pseudo
     CDS             24253..24627
                     /locus_tag="TV186_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24885..25667)
                     /locus_tag="TV186_001029"
                     /pseudo
     CDS             complement(24885..25667)
                     /locus_tag="TV186_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26184..27692)
                     /locus_tag="TV186_001030"
     CDS             complement(26184..27692)
                     /locus_tag="TV186_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1532433.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            27943..28839
                     /locus_tag="TV186_001031"
     CDS             27943..28839
                     /locus_tag="TV186_001031"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1532434.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28836..29099
                     /locus_tag="TV186_001032"
     CDS             28836..29099
                     /locus_tag="TV186_001032"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL1532435.1"
                     /translation="MKGEAGAPDTPQKPNDPLQSLEGGNSPIVEQNYGSTEGYHGQSG
                     ILEETEDTNPPGIILGGSGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29026..29832
                     /locus_tag="TV186_001033"
     CDS             29026..29832
                     /locus_tag="TV186_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1532436.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30204..31250)
                     /locus_tag="TV186_001034"
     CDS             complement(30204..31250)
                     /locus_tag="TV186_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1532437.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31252..>31392)
                     /locus_tag="TV186_001035"
     CDS             complement(31252..>31392)
                     /locus_tag="TV186_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL1532438.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9383 a         7384 c         6253 g         8372 t
ORIGIN      
        1 gaagctaaga agcctgaaca acctaaacca atgactaaac caggagctaa gaagcctgag
       61 caatcacttc catcaactgg tgacatcaga aatccattct tcacgcctgc agctattgct
      121 attatgatcg cagcaggtac cattgccatt ccaaaacgca aggaagaaga ttaaacaaat
      181 taacaatccc catatttcaa caatgataca caagccccta cttgtgtcca cctcaaaagc
      241 agtagccagt cgcgcggcta ctgcttttac tatgcttttt ttacaccagc tctgatagca
      301 gctaataaca aaaaagattg aagacacagc ttattgggtc cccgatcttt ttttggtcat
      361 acaaccaaca gcagctcttg aggcttgctg tccttctaag aggctgttgg cttgttgctt
      421 tagcttaatt ctgctacgat agccttgatt tgatccttgg tatggacgcc tgctacttgc
      481 ttgacaacct taccgtcctt tttgaacagc agggttggga tagacataat gccaaattgt
      541 tgagcagtat tgggattgtc atcaacatct agcttgacaa tcttaagctc agcttcgtca
      601 atttctgctg ctaattgatc aaggattggc gcttgcatta agcaagggcc gcaccaggtt
      661 gcccaaaagt ccacaaggac taggccttca ttagtttctg cttcaaatgt tgcatctgtt
      721 acgatatgtg ccattgtaat ctccgttctt atagtttata agcctatttt aggggaaaac
      781 gactgataat gcaagaatct gatacgaaga cctcggtctt atgatttaag aaaaatctgg
      841 cgtagccatt ttaagacaaa tacgctggcc tttgctacaa tgaccttatc ttaacaacta
      901 aaaggaggct actatggaag catacgagct tattgtgatt ggatttggta aggccggaaa
      961 aactttggct gccaaaatgg cgcagctagg aaaaagagtt gcccttattg agcagagccc
     1021 cactatgtat ggcgggactt gtatcaatat cggctgtatt ccaacaaagg ccttaatcac
     1081 tgctgctgag cataatgcta gctttgcaga cgctatggcg cacaaagata ctgttgttca
     1141 tcgtcttcgc caaaaaaatg agcagctgct agctcagtct ggtgtgacac tttacaacgg
     1201 taaggcaagc tttgtctcta ataagacgat tcaagtagaa gcagggcagg agcggatcct
     1261 cttagagggc aagcatatcg tgatcaatac cggagctgtt tcaaatcgct ttccgatacc
     1321 tggtctagca gatagtcagc atgtggttga tagtacaggg attctagctc tcactgagca
     1381 gcctcagcgc ttggctatta tcggtgcggg gaatatcggg ctagaggttg ccagccttta
     1441 tgccagctta ggcagcgagg ttactatgta tgaggctgca cctgctattt tagggcgcta
     1501 tgagccggtt gtcgctgagc tggcacagga ttacctggaa aaagctgggg ttacctttaa
     1561 gctctctgcg actgttgagc tgattgctaa tgatgaagca ggtagagttc tagtgactgc
     1621 taatggcaag acagaagcct ttgattgtct cctctatgct atgggacgta agcctgccac
     1681 tcaaggcctt ggcttggaaa acactgacat taagcttgat gatcgctatg ctgtcgtggt
     1741 agatgattat tgtcaaacca ctgtcgaggg gctatatgcg gttggtgatg ttaatggcgg
     1801 gcctcaattt acctatacgt ccttagatga tttcaggatt gtgtttgggc agctaacagg
     1861 cacaagccag tacaaccaca aagatcgggg ctatctgcca acaacagtct ttatcgagcc
     1921 gccactttca caaattggtc taacagaaaa agaagcaaaa gagcagggac tgccctacaa
     1981 ggctaatgag ctcttggttg ccaatatgcc acgcgcccat gtcaataacg acctcagggg
     2041 gatttttaag gtcattgtca atacagagac taatgaaatt ctaggggcaa ccttatttgc
     2101 taacaattct cacgaataca ttaacctgat taagatggct atggataacc agattccata
     2161 tacctatctc aaaaaccagc tctttaccca cccgtcaatg gctgaaaatc ttaatgatgt
     2221 ctttaacctt taaaagaacc tcaacctcac ctgcatagca ggtacaacag ccaaactatt
     2281 aaaaaaacaa actccttttt ggctgcttat cacatggata ggcggctagc aaaaggagct
     2341 tgttttttct tgtatccaat cagcaggcta gcagctgctc atggtctaaa ggaactagct
     2401 aggctgggac acgttggtag caaaagtcca gcaagactca ctagctgctg tcatgagctt
     2461 tgaagagcag cacttaggga acacgcccag tagctttctt tgggacgctt ggctcaccta
     2521 gggctcaatc agcttgagta aaaaggggct ttatttgaat caagaggatc aattagccta
     2581 gattagctat ggtacagcct gagccgccag cattttgcgg ggcatagcca aagcttttga
     2641 catgcttgtt gcgtcgcaag tacttgccga ccgcttcacg tataacacct gtaccaatac
     2701 catgtatgat gtcaacctga ctcatgttgt taagcaaggc ttggtcgata aaggcatcta
     2761 gctcctgcat ggcctcctca tagcgcttgc ctcgaaggtc taagcgagcg cgcggccctt
     2821 ttcctgtagc tgcttttttg acgaccttga cagctctctt cttaggctgc tgcgcttctt
     2881 cttttagctt aaccaagctg aattcgtctt ccttgagggt caacttgatc aggccaacct
     2941 gagcctccca cctcttgtcc ttaagctggg caagcaaggt tcctctttgc ccataggcgg
     3001 taacaatgat gtcatcaccc acacgaggag cccgccattt tttcgctttt ttcagcacct
     3061 tattttgcga caggctttgc tctggcgcaa gctgctttag gcgatgcttg gcttcgataa
     3121 tttcgtgcgg ctttagctct gccttttcat gcagctgact taaaatgcta tcactttctg
     3181 ccaaggctat atccacaatc tcacgcgctt caagggctgc cttttccaat tccttgtcct
     3241 tagcgtggga gaactcgtta tagagctttt taacagcacg attgaatttg aggttatcct
     3301 gctcgacctc cttgatatgc tcaaggcgct tgcggctttc taacgtttgc tgctctagtt
     3361 gctcaatgat acgattgaca tcatgatcag ttgcggtcat cgcctgagct tccttgacga
     3421 tgtgctctgc taagcccaat cgtctcgcaa tgtcaaaagc atttgagcga ccaggcactc
     3481 cttgcatgaa gcggtaagta ggctttaggc tgacattgtc aaaggccatg ctggcatttt
     3541 caacataggc tatctcaatc ccataggcct ttagctctgg gtaatgggta gtggccatcg
     3601 tcttaatatt ggtcagacgc agctgctcca aaatagccat agcaaggctg gctccttcct
     3661 gtggatcagt ccctgctcct agctcgtcaa agaggatcaa gctgtcactg tctgcctgat
     3721 tgagaatctc aacaatgtga gtcatatgac tggaaaaggt agacaggctt tgctcaatgg
     3781 attgctcatc tccaatatca gcataaatac cattaaaaac tgccaccctg gagcccttgt
     3841 cagccaaaat aggcagccct gactgggcca tcacctgagc aagccccaag gttttgagca
     3901 tgatggtctt accacctgta ttaggaccgg tgatcacaat tactgctaag tcatttgcaa
     3961 aatgcagatc atttgccaca gggttttgaa tcaaggggtg gcgcgcattg agcagctgta
     4021 agcttttatc gtcagaaatc actggcacag ttgcctgttt ggcttgcata taaaggtatt
     4081 ttgctctcac aagatctaaa tgtcctagta gccaagcgtt attcctaaga gatcgactat
     4141 gcggacgcag ctgctctgac agctcatgca agattcgtcc aatctcatgg cgttcatctg
     4201 tctgtagctg agtcagctcc tcattgagac ttacaagcgc tctaggctca atgtagaccg
     4261 tactgccaga agctgacatg tcatgcacaa cgcctgccac cttatgacga taggtgtttt
     4321 tgacaggcag gacacttcgg ccattacgac tagcaatcag gctctctgac aaataagctg
     4381 cctgtttttt taggatatcc tgcaggagct gacgactggc atgctccttg tttgatatct
     4441 gacgacgaat gctctccaat tcaggactag caaagccttc aacaaagcct gcgtcattaa
     4501 tggcttggag actcccctgt aagctaggaa agctctctat tttttcaaag agtgctttta
     4561 gagcgactaa atcaacattt tccaaatcag cgtaaaaacg acagacctct gccgacacct
     4621 gcaggagctt tttaactgct aaaagctctt gaatgctcag atctgcctct aaatccaaac
     4681 gctgcatgct ttctgagaca tctgatagcc ctcccaaggc aaaatggtgg tgctctacaa
     4741 aaatagccgc catttcctca agctctgtaa agtaagcctg tattttgtct ttattcgcaa
     4801 taggctccaa caagtcaagc tctagctgcc cctgctctgt ctgtaaataa ggccaaaatt
     4861 gctctttaac cttttcaaat tctaactgtt ctaaaatctt tttttccata gttcttatta
     4921 tacctaaaaa tcacttaaaa tgtgggacac taaacaaaaa gagaccagag agactctgac
     4981 ctcaaagaat agctgttacc cataattgcc tgagaatgct tgagataaag ggacaatgct
     5041 caaccaagag gcgagacaaa agactgccat gtaggcgccc ttgaataaag ggcatgggaa
     5101 tggtagcaag aacggtcaat gccatgctta aaaacaaaac cgaaaccatc accgccagca
     5161 agccactggc tagcttagcc tcaaagccat caaaataatc caccggcgca aggtgcacca
     5221 agacacccgc caatcgaacc acagcatagc ctactgtaga cagtataaaa aatgctatcc
     5281 ctgcataata aaccttatcc aattcaaaaa tattaatatc cttaaaaaat aaggtagctg
     5341 ctccctcagc aggattagaa taaggcaccc atagagccag cttgcctgcc agagccttat
     5401 agccatgatg ggcaaacaag agcgacacca aggccccaaa acaataaaag gtctgaagga
     5461 taagccctct attgtagcca atgtaaaagc tccaagaaag cagtaacaat ataagcactg
     5521 agagcatcat gacacctcat ctgtatctgc ttgactagcc ttttcctgaa tacctgccag
     5581 tgccttctca cgcagctcga caatctcagc ttcgattttt tcaatctcaa tctctctact
     5641 cagttgggct gacagggtat tgatggtcat caaaatagca acggtttcgt cgtctgcttc
     5701 tggcagacgc tccttgatgg cctgatattt ttcctttgcc acacgatcaa cctcttccat
     5761 aaagaggttg tctttgtccg ttgtcaatgt taatgtcttc tcaccaaatg ttaatttgta
     5821 acgattaata ttcttcatag gctcacccct ttagcattat accctaaaaa tgacttttcg
     5881 taaaattgtg aaattaatct gagattgcat ggaatgattt cccataacag gacattttat
     5941 gttaaaataa tgttcatgga caccttagtt ttcaaaatca attcccaagt cagcagcagc
     6001 ctgatcaagc agctagcacc ataccgcata agcaatgcca atccttacgt tagactggct
     6061 gccaaaaaag atggtgtcac actgatgctg tatacctcag gcaagctggt gctgcaaggc
     6121 agacaggctg caaagctggc tcaagagctt gatctgcaag aaacgcctgc tgatcagaga
     6181 cccgcaccct ccagcgcaca ggatatcccc ttaattggta gtgatgaggt gggaaatggc
     6241 tcttactttg gaggcattgc tgttgttgct agctttgtgc agccagagga gcacgccttg
     6301 ctcagacagc tcggtgtcga tgattctaaa aacctcaatg ataagagtat cgcccagatc
     6361 gctcctgtcc taaaaaagca tattcaacac agggcgcttt tgctatcgcc taaaaaatac
     6421 aatgaaatgg taggtaaggg gaagccctac aacgctgttt ctgtcaaggt tgctcttcat
     6481 aatcaagcga tttttctgct cttaaacgac ggagcaagac cagaaaaaat tgtcattgat
     6541 gccttcacaa gtcaggccaa ttatgacaaa tacctacagc aagaaaaaaa tcactttcgt
     6601 aatcccttga cctttgagga gaaggccgaa ggcaaatatc tggcagttgc tgtcagctct
     6661 atcattgcta gacagctatt tttagacaat cttgacaagc tcagtcaaga tctgggctac
     6721 cggttgccta gtggtgctgg gcgtccatct gatcagattg ccagtcaaat cttagccgcc
     6781 tatggtatgg caggcttaga gcattgcgct aagctgcact ttgcaaacac caaaaaagcc
     6841 caagcgctac taaaaaaaca ataatcttag aaaaataaag gaaaagtcat gaaacaattt
     6901 attaaagaat ggggagcttt tacccttttt atcctacttt ttggactctc acgtttgttc
     6961 ctatggcagc ctgtcaaggt tgatggccac tcaatggacc caaccctagc acatggcgag
     7021 aggctcatta tcttcaacaa ggctaagatt gatcgctttg atattgttgt tgccagtgag
     7081 gaggacgaga acggacagag aaaagagatt gttaagcgtg ttgttggcat gccaggtgat
     7141 aagctgtctt atagaaatga cactctttat atcaacaaca agaaaacaaa agagccttat
     7201 cttgatacct acctgacgag ttttaaaaag gacaaattac aatcaaccta tgcttacagt
     7261 gatctcttcc aagagctggc tgaaaatgct gctgccttta ccgtcaactc cgaaggaaaa
     7321 acagaatttg acatcactgt tccaaagggc gaatatttcc tactgggtga tgaccgcatt
     7381 gtatctcgtg acagccgcga ggtcggctcc tttaaaaagc aggacatcgt tggtgaggtt
     7441 aagttccgct tttggccact caataaaatc aatctcttcc ctagatagca ggcaagctaa
     7501 agctattttc tagcagggct gatataggct ctatgcccac agcagtaaag actcagggca
     7561 gcaatagcct ctatctatat ctgcttatct atccatacca agaggcttga tgtgctatcc
     7621 aagcactcag ctagctttag agaagcagct attgttgacg ttctaaaacc tgccgttgtg
     7681 caggttttcg actatcttgc acagaaaggt accgtcatgg aacacttttt tacaggcact
     7741 gttgaccgaa ttatctttga caatgcgtca aattttttca aaattctatt actggctata
     7801 gaggatactg atagtgattt tgatgaagct gacattgtca ttacaggcac tatggctgag
     7861 atcatagagg gcgaagccta taccttttgg ggtgagctga cccagcaccc aaggtatggt
     7921 cagcagctgc gcctgagccg ctatcaaaag gctaagccca cctcagcagg tctcgttagc
     7981 tatttttcca gtgagcattt caagggcatt gggcaaaaaa cagctgagaa aatcattgcc
     8041 ctttacggta ataatcctat tgatgagatt ttaaaaaatc ccagtcggct taatgagatc
     8101 tctagccttt ctaaggctaa tcgtgaagcc tttgtggcaa agcttaaagc caattatggc
     8161 actgagcagg tgattgctgc cttggctgat ctaggactgg ccaatcgctt tgcctttcag
     8221 ctatttgaca aatacaagga agaggctgtt catatcgtca aggacaatcc ttatcaactc
     8281 attgaggaca ttcaaggctt tggctttaag ctggctgata gcttagctga acagctagga
     8341 attgagagtg cctctcccaa gcgctttcgt gcggctctgc tgcattgcct gttggagcaa
     8401 tccatcaagc gaggcgacac ctatatccag gcacgtgagc ttttggcgct gaccattagc
     8461 ctattagagg acacaaggcc agtcgaatgc gacccagcta ttgtcgctaa tcagctaacc
     8521 cagctcatcg acgagggcaa ggttatgact attggcacgc gtgtttttga cagcagcctt
     8581 tattatgccg aagacggcat tcaaaagcat ctgacacgct tactacagca gcctctgact
     8641 aaggagccta gtcaagatac cattgaccaa gaaatccaag ccatacaaga ggagcttgct
     8701 ataacctatg acaagatcca aaagcaggcc atcagccagg cactgaccag caaggttttc
     8761 attctaacag gaggcccagg cacaggaaag acaaccgtta tcaggggcat tttacaggcc
     8821 tatgccagcc tgtaccagat tgacctgaaa caaaaggata ttcccattat cctagcagct
     8881 ccaactggtc gagccgctcg tcgtatgaac gaattaaccg gtctagcaag cgcaactatt
     8941 caccgccatc ttgggttaaa cggagacaat gattaccaag caatggagga ttatttagac
     9001 tgtgatttgc tgattgttga tgaattttcc atggttgata cctggctggc caatcagcta
     9061 ttaacagcca tcaattctaa tacccagctg atcatcgtag gagatagcga ccagctgcct
     9121 tctgtcggtc ctggacaggt actagctgac ttgctaaagg ttgatcggat ccctcacatt
     9181 acccttgaca agatttttcg ccaatcagag gagtcaacca ttgttgattt agccaaccac
     9241 atacgccaag gcattcttgc tcctgatttt tgtcagaaaa aggctgatcg ctcctacttt
     9301 gaagcgcaag cgccattcat tcccggcatg atgacaaaga tcgtacaggc tgccctaaaa
     9361 agtggcatcc cagctgagga aattcaaatc ctagccccta tgtacaaagg actagcaggc
     9421 atcaacagcc tcaaccagct catgcaaaac ctcctgaatc ctctagctaa tcagacagaa
     9481 tttctcttta acgagacggc ctttcgtaag ggagacaagg tacttcacct tgtcaatgac
     9541 gctcagctta atgtcttcaa tggtgatatt ggctatatca cagacctcat tccagccaaa
     9601 tataccgaat ccaagcagga cgaaatcatc atggactttg atggcaccga gatcgtctac
     9661 ccaagaaatg aatggttaaa aatcaccctt gcctatgcca tgagcattca caaatctcaa
     9721 ggcagtgaat ttcaggtggt aatcctgcct gtcacccgtc agagtggtcg acttctgcaa
     9781 agaaacctca tctacactgc catcaccaga tcaaaaagca agctcatcat gctcggagaa
     9841 atagccgcct ttgaagaggc aatcaaaaaa gaaggtgaca agcgacacac ctatctcgta
     9901 caaaggcttc aagtggctga agctgatgac catacagcag ctgcttcagt aaaggaatca
     9961 aatcagtcta gcctatctgt aatgccagct accagcccac aaaaggaaca agagcagcct
    10021 ccttatctgc tcacccctca taatttccta gctatagacc ccatgattgg tctaaccgaa
    10081 gatgatatgt taaccttttt taagaaaaaa tcataatata ttaaaaaagt aaggcacaat
    10141 ccttattcct atgctataat atccatgtat catcttaaaa gtacaataac ataacattca
    10201 aggagactta tatgatttca tacgaacaag tacgacaagc actcagaaca tcaactatta
    10261 cgatcattat catcaatgct atcagcatgg ttatcacctt gtttggactt gctggcattt
    10321 tctttttgaa gtctcaattg gataaacctg aatttcgtgc acaattttca gctgagcagc
    10381 taaggctatt tgaggttggc atatcaccct ttactatttt tatgtcagtg attagccttg
    10441 gattggttgt tttgaccact gtgctttgtg gctttaacct ctcaaaaatc aaacaaggtt
    10501 ccactgtcag ctatgttcct tacattatag ggattgtgct ctatcttatt agtatcgtaa
    10561 gccaactatt tagccaaatt gagcctgtct caatgatcat tgtcctagct gagcttgcgc
    10621 tttacggctt tgccttttac aaggctaaaa cccttaatga aaaagacaag gacaatcccc
    10681 aaagcattga agaataagca ggccataaag gtatgataac aagacttcct gtctgccttc
    10741 aaatatggct ctttgtcagc ccactacggt tgacaaagag ccttttttaa ccactaaaaa
    10801 agcaagagga aaattgataa tgtcctcttg ctttttttgt tagttgaatg acaggtccaa
    10861 caaaatatct gtcactttat cctttagtcc ggtcattgtg actcccaata agcggattcc
    10921 tgcctgatgc tcctccaggc tatcaaaaag ctctctagcc acctgatcaa tgatcctagc
    10981 atctcttgtt aactcaggta ggctaacccg cttggtcaag gtcgtaaagt cagcataccg
    11041 aaccttcaaa acaatgatcc ttcctagttt tttattcgcc tcaagcaaat cagcgacccg
    11101 tcttgcatgt ttagaaagct ctgccttaat atcagcctcc tggtagagga gcttagcata
    11161 ggtacgctca ctgctgatgg atttgcgcat acgattaggc ttgactggag aatgactaat
    11221 gcctctggcc tttcgataaa gctcatagcc aaagcgtcca aactgatcaa tcagggtcat
    11281 ctcaggaaca cgcaaaagat cctgcccagt gtaaatcccc atctcatgca gcctttcaac
    11341 tgttcgctta ccaacgccat gaaacttttc aatcggaagc ttttctaaga atggcagagc
    11401 atcatcagga agtactaggg tcagaccatg tggcttttca aaatcactag ctagcttggc
    11461 taaaaatttg ttataagaaa caccagcaga gcaggtcaac tgcaggctat tccaaatatc
    11521 atgctgaatc agtcttgcaa tctttaaggc agacttgatg cccagcttat tggttgtcac
    11581 atctaaataa gcctcatcaa tagacacagg ctccacctga tccgtataac gcttgaaaat
    11641 ctctctgata tcatagccaa tcctacggta cttagcatga tctccagaga taaaaatagc
    11701 ctgaggacaa cgctcgtagg cctcctttga gctcattgca gagtgaatgc caaaccttct
    11761 tgcctcgtag ttacaggttg atacaacgcc ccgtccacca ctttctctag ggttcttgcc
    11821 gatcaccacc ggcttgccct ttaattcggg attatctctt tcttccaccg cagcaaaaaa
    11881 agcatccatg tcaatgtgta taatcttgcg tgaggtgtca ttaatcagcg gaaaaataag
    11941 cataggtccc tccctcctac attatactcc tttaggcttt taaagccaag gcagaggatt
    12001 gtatgacagt tttcaactgt ttcagcaaac tgtaatataa aagaatcttg tatttgtcaa
    12061 gatttttgct tgggaaatcg tttcccctat ggtaaactta gattgtaaat gtaacagatt
    12121 ggacttgtta ctagatttta aggagaaact tatggcaact gttaaaacta acgcagatgt
    12181 ttttgaaaaa gcttgggaag gctttaaggg aactgactgg aaggaaaaag cgagtatatc
    12241 tcgttttgta caggctaact atacacctta tgacggtgat gaatcattcc tagcaggtgt
    12301 tactgagcgt tcattgcaca tcaaaaaggt cattgaggag actaaagctc actacgaagc
    12361 aacacgcttc ccatacgata ctcgtccaac ctcaattgct gacattcctg ccggatttat
    12421 tgacaaggat aaggaattaa tctttggtat ccaaaacgat gagctattca aattgaactt
    12481 catgccaaag ggtggtatcc gtatggcgga aacaactctg aaggaaaacg gctatgagcc
    12541 agatcctgct gtacatgaga ttttcactaa gcatgtgaca acggttaatg acggtatttt
    12601 ccgcgcttac acgtcaaaca ttcgtcgtgc gcgccatgcc cacactgtaa ctggtctgcc
    12661 agatgcttac tcacgtggtc gtatcatcgg tgtttacgca cgtcttgccc tctacggagc
    12721 agattacttg atgcaagaaa aggtcaacga ctggaatgcc atcactgaga tcgacgaaga
    12781 atcaatccgt cttcgcgaag aaatcaacct gcaataccaa gcacttggcg aagtggttaa
    12841 gttaggtgat ctttacggtg ttgacgttcg tcgtcctgct gaaaacgtca aagaagctat
    12901 ccaatgggtt aacattgcct ttatggctgt ttgccgcgtg atcaatggtg ctgctacttc
    12961 tcttggacgt gtcccaatcg ttcttgacat ctttgctgag cgtgaccttg cacgtggaac
    13021 cttcaccgaa tcagaaattc aagaattcgt tgatgatttt gtcctcaagc ttcgtaccgt
    13081 taagtttgct cgtacaaagg cttatgacgc tctttattca ggtgacccaa ccttcatcac
    13141 aacctctatg gctggtatgg gtaatgacgg tcgtcaccgc gttacaaaga tggactaccg
    13201 cttcttaaac acacttgaca atattggtaa ctctccagag ccaaacctaa ccgttctttg
    13261 gactgataag ttaccatatg ctttccgtcg ctactgtatg cacatgagtc acaagcactc
    13321 ttcaatccaa tatgagggtg tgacaacaat ggctaaggac ggctacggtg aaatgtcatg
    13381 tatctcatgc tgtgtgtcac cacttgaccc agaaaatgaa gagcaacgtc ataacattca
    13441 gtacttcggt gctcgtgtga acgtgcttaa agcccttctt actggactta acggtggtta
    13501 cgatgatgtg cacaaggact acaaggtatt tgacatcgac cctgttactg atgatgtcct
    13561 tgactttgat actgttaagg ctaactttga aaaatcactt gattggttga ctgatactta
    13621 cgtagatgcg cttaatatca ttcactacat gactgacaag tacaactacg aagctgttca
    13681 aatggcattc ttaccatcac atcaacgtgc taacatggga tttggtatct gtggcttcgc
    13741 aaatactgtt gacaccctat cagctattaa atatgcgact gttaagccaa ttcgtgacga
    13801 agatggttac atctatgact acgaaacaat cggcgactac ccacgctggg gtgaggacga
    13861 tcctcgctca aacgaattag ctgagtggtt gattgaggct tacactacac gtctacgcag
    13921 ccacaagctt tataagaacg ctgaagcaac tgtgtcactg cttaccatca cttcaaacgt
    13981 tgcttactct aagcaaactg gtaactctcc ggttcaccgc ggtgtttacc tcaacgaaga
    14041 tggtacaact aacctatcac aacttgaatt cttctcacca ggtgctaacc catctaacaa
    14101 ggctaagggt ggctggctgc aaaacttgaa ctcacttgca agccttgact tctcatatgc
    14161 cgcagatggt atctcactaa caactcaagt atcacctcgc gcgcttggta agacacatga
    14221 cgaacaggtt gaaaaccttg ttactatcct tgatggttac tttgaaaatg gtggtcaaca
    14281 cgttaaccta aacgttatgg acttaaatga cgtttacgat aaaattatgg ctggtgaaga
    14341 cgttatcgtc cgtatctctg gatactgtgt caataccaaa taccttacac cagaacaaaa
    14401 aactgaatta actcaacgtg tcttccacga agtgctttca atggacgatg ccgctgaagc
    14461 tatttcagga aaataagcta atcttagcta gctaagagcc tgtctgttga caggttcttt
    14521 ttttatcaca catgcaatag gtacagctgt cctcagcagc tgaataacca gcagagctgg
    14581 ttgaaactac tagcaagcct atcattatca ttgtgaaaat cagacgatta accttttcat
    14641 taaaaaaaaa aaaacgaaac tacggagaaa agctgatgag gagctcttta aggctatcag
    14701 tcaacatgtt aaactcttct taggaagcgt taacaataac taactgctaa gctaagcaat
    14761 tatctattaa ggagaataac aatgaaacga ctaaaaacac tatgcttgtt agctactgct
    14821 ataaccctaa ccctagctcc tatcagcaca agccagacaa caacacagac cgtatatgct
    14881 agtgaaactc atcaaaatct ttgtacgaac actggtaacg gatggtttaa atgtcccgat
    14941 ggacatggag ggtggacttg gcattttgac gaaaatcata agtcaaatca gcagtccttt
    15001 ttgggaggat tgttgggctt tgctttgtct ctatggggag ctattattag actcttttaa
    15061 gctctagctt aactaatcct caaacaacaa aaataagctc ttagagaact aagctctaag
    15121 ggctttttgc tgttctgata agtaaaaacc aagagacaag gacatcaaaa acaagcaggc
    15181 ctatcagata taccacctga taggcccact tgtgctctca ttcttatcta ggactatttc
    15241 tgtcaaaggt cctatgaata gcatcccgaa gctgtcgtct ctctttgatc cacaaggccc
    15301 tatcatcctt gtcataggtt ctattggtga gaaaaatcgc tgcctgctgc tcctttttat
    15361 tgagcatgat aaaaggccct gtatagcctg tatgactaat ccaatcaccc tctaggctcc
    15421 aacccaaaga cctgggcttt tcctgtctgc tatagctttg aaaaagtcta tccgaaaagc
    15481 tttccttcag gtaatgctca ataaaccgct ctaaatccct gatggttgaa aaaagccctg
    15541 ctgagcctgc atggtttccc aagaccttag ccttgggatc atgtacctct ccatcaagca
    15601 cccctttgac cgttggaact gcttctggcc ttgggccaaa ggaggtctca gtcattccaa
    15661 agggagtaaa aaccatctcc tgaaaaagct catcaagaga ctttccatga aggtgctcta
    15721 gcatgaagcc aagcaataaa aaattcacat ctgtgtaatg aaaggtctta tcgtccttga
    15781 cctgaagctg gtgcatcgct gctcttaatt gctgggcatt gagctgatct cgattgggaa
    15841 tataagggtc aagtccacta gtatgggtga gtagctgtcg cagtgtaacc tccagctttt
    15901 gagcgtcagg ataataatgc cttaaaggag tatcaagagc caaggcacca ctattgatca
    15961 tggctataca gacagtcgct actccgacaa ccttagagac actggctaaa tcataaacca
    16021 agcctttggt aacaggtctt tgaccatcaa gggtaccgat ataatgctcc tgccaaccgc
    16081 cacagcgaaa aagggctaag ctagccccat gatataagcc ttcctgaatc tgctggctta
    16141 ccttttctat gacttctaat gtcatttgac aaaccaaatt tcgatctgac ttgggtctga
    16201 aagaacaagc acccttgcct ttttatctaa ataaacctga caccctttgt cctcaaggta
    16261 ggtctttaga gcaagcaagt catagctatc tgacacctga aattctaaaa tctccaaatc
    16321 ccatgtgaca tgcgggacaa tcgtcaaatc ttgaccagcc tccctattaa actcaagcgt
    16381 gaccggcagg caatcaccaa aaatagactg ataaaaagct ctggattgct cgtcatctaa
    16441 aacatttaag acaatcagat caaagctaaa ctgactcagc cccctaaagt cagcttcctt
    16501 gtcaattgca ggaacatcat cgacaatgtc aagctccttg atatcgtcct ctgcatggag
    16561 taagaagcga tctccctctg gtgaggtgac ttcaaaggca tagccttttt ttcccttgaa
    16621 aatcaaatca tagtcaacgc catgagctag gagctgctca atgtccttag gagcagttgt
    16681 tttgataaca attgtattta ctttcttagg gccatctaca acgcgtgttc ttgctgctgg
    16741 agattcttca attacaaagc gttcttgtcc ttggccccaa gatgaaaaaa ttgatatcgc
    16801 gttttcctct gacactagcc ttaagcctag atttttttgg taaaaggcaa tattaaggtc
    16861 gcgattgtta acacgtaata ctggggtttt aaagacaata ttgtcaaata aagtcatata
    16921 ttcctcctaa tcctctgcta ttatagacaa aattccaatt tttgacaaga aattatatgc
    16981 tttttaaccg cctgtcacgc gctaccaagg caatatagca ctcacagcca tcaccagact
    17041 tactaggtcc aatcttcctt cgtgcgctct atcacaagca gctttcctta gcgtaactca
    17101 tgcacatatt ggtaaatgcg actttttcaa aatagcacat gaagtacccc tttaatttga
    17161 cttttcctta accaaaagcg agaacctttt ttagttctca cagtagcaat cacactcttg
    17221 aaatgtgatt tcgctctcct caataacaga tgataactga aattgcccgg attttcttat
    17281 ccacgcgcaa cttcaaaagc accttatctt cagcattagt aaggatacta ccagcttagc
    17341 tcagaccaga ttcagctggc tcttgctggc aagcttttat cacaaaaaag aaggcctaag
    17401 ccttcttttt tacttgatat aaaggaattt gaatgctgct actgctgcta ctgctgctag
    17461 cactggggca gcaaccggta cccatgagta ccaccatttt gaatccccct tggcttgtcc
    17521 aaggactgat tttggtaaga aatggtgaac caaacgaggg cctaagtcac gcgctgggtt
    17581 gagcgctgga ccagtaggac caccaagaga ggtcacaaga gtcatcacca agaaaccaat
    17641 ccccaagtga gctactgcaa gtgagcctgt cacgtaagga gagatttgcg ttgcagctgt
    17701 tgtttggtca tagccagcct ctaccagctt accaacaagc tccacaccaa agtaattctt
    17761 ggttaaggcc attgcgccaa aaaagaggac aaaggaacca acaaactcgt tcaaaaagcc
    17821 attaatgtag gctgccttac ggctgccctt gtcaccatca tcaactgctg aaatcgttga
    17881 gaaggatccc aaaatattgt tagggttgtc tgtctgcaca aaataaggct tgtacaccgc
    17941 aacaaccact aattggccaa acatagcccc tagcaattga gcaagaacat attgtaaaac
    18001 gtgtgcccaa gggaacaagc ctgaaactgc caagccaaag gtaaaagctg ggttaatgtg
    18061 atttccagaa acgttaccaa acataagtgc cggcatcatc acaccgaggc catagccaaa
    18121 ggcaatcaca agccagcctg agcggttacc ctttgttccc tttaagtcaa cattggcaac
    18181 tgctccattt cccaaaataa tcaaaaatgc agtggcaata aactctgtga tgtatttcac
    18241 agtccatgtt atttccatat tctctagttt cctccaaatg ataagtataa cagataccat
    18301 tttatcaggg atactagttc ttgtaaagcc tattgtaaga tattgcctgc ttaatatgtt
    18361 tacagtgttt tttcacaatt acggacaact aataagtctt ttttagcatg tcgcaggata
    18421 tactctgagg tcgatccaat cagcagacgc tcaaaggtat ttaagccagt tgctcctacc
    18481 atgatcaaat cagcctgctc cttttcaggt atgtcactag ctaagagctt tttagggttg
    18541 cctctttcga tgattttttt aatgctgcta acgcctctgc ctctagccat tttctcgtaa
    18601 tagcgcaaca cctccttggc atgctcctct tgtgtgtcaa agacataatc actaaccatt
    18661 gcatcaccct gataggcctt aacatcaata acatgagcca gcagtaagac cgcatcattg
    18721 cgaagggcaa cattaatggc cttctcaaca gctaattctg attcgtaaga gccgtccacc
    18781 gcagccagaa tccgtttata tttgcttatc atctttgtct cctttcgttg attagccttt
    18841 atcaatagcc tttgcttgtg tctttaggaa atacatgact gcgcaggcag ctggaatgag
    18901 ccctgccagc cagaacaatt gatgaaagga ctgcacacca gacccaagaa gcatatcctt
    18961 gatgagtccc aacagataag gtcccgcacc caagcccaaa tctagcccaa tcatataagt
    19021 agacatagcg gtattaaagc gatgctcctc aacccccttg atggaggctg cctgtccgca
    19081 ggacataaag gttccatagc caaagcctat caaagcaccc gaaagcagat agggaaggct
    19141 gcttgtcaca ctaccaagca ggaaaagccc tagcgccaaa aagagatagc tgggataaag
    19201 aacccactgc tcccccttaa cgtccatcaa gcgtcccata gcaggtcgtg tgatcgtaat
    19261 gatcaaggca tataccacaa agaaataggc tcccaccgtc gtcaaatgaa tgtctgttgt
    19321 gtataatttt tgaaagccta gcacagaagc ataggcaatc cccatcaaaa aggcaatcaa
    19381 ggtgataaat aaggcctttc gctcaataaa gctatcaact gtccaggatt ttgtttttgc
    19441 cagctgctct gagttgaggg caatatctgt cacaggaaag gcaaaggccc ctagcacaac
    19501 tactgcgatc aacacactgc acaaaataat aatcatccga aaatcaatgt gcaaattatc
    19561 cagcataaag gtcccaacaa aaggaccaat cgccgccgct aggcttgttg atagaccata
    19621 aaaattaatc ccctctccgc gcttgctagc tggaatatag gcagtcacaa tggtattggt
    19681 tgctgttgag acaacaccat agccaaagcc attaaacaag cgcacaaaat acatcatgcc
    19741 aatcgttggc atgaaaaagt aggctagcgt tgttaggaga taaaaaatgg cgcctcctct
    19801 tagcactaag cgtcggccaa aaacctccaa ttgcttgcca aaaatcagtc gagccagcag
    19861 ggttcctagg atataaatcc ccgtcgccag acctgcctca ctggtcttag ctcctaattc
    19921 cttagtcgca acaaaggcaa tgatcaccgt aaacaagtaa tagaccatat acacaataaa
    19981 atttaatact gtgatcccta taaaatgctt gttaaataat ttgtcttcca ctgaaaatga
    20041 gctcctccct atttcattaa cattttacaa aaaaatcaga taatgcccca tttcaatggt
    20101 ataatatagg tgatactatt aaacgacatt agcaaatgct aagcattgct gcagcaacaa
    20161 attatataat gataccagaa acacctctag gagaaaagcg tgaaccatca aatcttacag
    20221 cgttatattg acagtcataa ctttcctatt atcgaaaagg gctaccacaa atacctgacc
    20281 tttgaaagct tagaggagga ttttacgtat atcctaaagg agggcattgt caagcaaagc
    20341 gttctgtcaa aatatggcat ggaatttaac ctcaggtacg tcacaggcct tgagatcacc
    20401 tctgtgctta atactggcta ttccaaggac atgagagagc cctacaatgt tcgcatcgaa
    20461 tctgagactg ccagctttta taaggttcgt cattccacct ttttaaggga tattagcgag
    20521 gatatcgagc tgcagggcta tgtcaaggac ttttatcact accgcctcca aaaatcaatg
    20581 aaaaaaatgc agtgtatgct gacaaatggc cgtatcggcg ctatctctac tcagatttac
    20641 gatttaatga ccctttttgg acgccccttg gctaatggcc atatccttat tgattttatc
    20701 atcacaaatg aggagctggg caaattctgt ggcatttcga ctgccagcag tgtcagtcgt
    20761 ctcctaaagc agctcaaaaa agagggcatt attcaaatca atgaccagca tatcatcatt
    20821 accaatttag agaagctaaa ggataatatt gttttttaac gatttagaaa ggacgtccca
    20881 tgcgctataa tcaattgtct tacattccca ccagtctaga aacagctgta gctgagcttc
    20941 aggccctggg ctttgctgtc cagcaagagc aagcacccaa ggagaacttc gctattttcc
    21001 ttagaaagct attttttcat tttcaggata ccgattatcc cttgagccat atgattgcaa
    21061 gcaaggatct cgacctattg acctttttaa catctgatgc aacactgaca aaagaggttt
    21121 ttgatttagt ggccttacag gtccttggct ttattcctgc tgttgacttt accgatgcac
    21181 aggactttat acaaaagatt ggctttccga ttgtttttga cagccagcaa ttactactca
    21241 atttacatca gctgcttgca acccggcaga agtccggtgt gaccttgatt gatagccttg
    21301 ttagtcaggg cttgcttcct atggataatt gctaccacta cttcaacgga aaagccctag
    21361 caacctttga taccaccagc ctcattcgcg aggtggtcta tgtcgaagcg ccacttgata
    21421 ccgatcaaga cggacagctt gacctcatca aggtcaacat tatccgcccc aaggccagca
    21481 ctgctatccc aagcatgatg acagccagcc cttatcacca agggattaac gagaccgcca
    21541 acgataaaaa gctccatcgc atggaaggtg agcttagccc taaggctcct cgtaggatta
    21601 ccgttgagcc aactgatttt cagccgcttg ccaccaagcc ctcaaggctt cctgtcaatg
    21661 agtgccaaga gaccttcagc catatcagct cctacacact aaatgattat tttctagcgc
    21721 gtggctttgc caatctctat gtctcaggag tgggaacagc aggctcaact ggctttatga
    21781 caagtggtga ctacgcccag atcgaaagct ttaaggctgt tatcgattgg ctaaatggca
    21841 gagctactgc ttacacgagc cacaagcgtg actatcaaat caaggctgat tggtcaaatg
    21901 gcttagtcgc aacaactgga aaatcctatc ttggtaccat gtcaacagga ctggctacaa
    21961 caggtgttga tggcttagca gtcatcattg ctgaagctgc catttcttct tggtacgatt
    22021 attatcgtga aaatgggctg gtatgcagtc ctggtggcta cccaggagag gatctcgatg
    22081 tgctgacaga gctcacctac tcgcgtaacc tgctgccagg tgattactta cgtcacaacg
    22141 accattatca acagctgctg agccaacaat ctcaagctct cgagcgccaa tcaggcaact
    22201 acaatcaatt ttggcatgac cgcaactacc tgccacaggc tgatcgcatc aagtgtgagg
    22261 tcgtctacac gcatggccta caggactgga atgtgaagcc tagacaggtc tacaatatct
    22321 tcaatgccct gcctgatagc cttggaaagc accttttcct acatcatggt gagcatgtct
    22381 acatgcacaa ctggcagtca attgattttc gtgaggccat gaatgccctg ctctgtcaaa
    22441 aaatgctagg acaaaataat ggctttaccc taccaacaat catctggcag gataaccaaa
    22501 aagaacaaac ctggaaagag ctaacagcct ttggcggtca cagcaagcgt cagattgccc
    22561 taggcgatga tcatgtctta attgacaatc actatggcga agaggacttt aagcgctata
    22621 gcaaggattt tcgtgccttt aaagctgagc tttttgaagg caaggcaaat caagcagtca
    22681 ttgatattct gttagaagag gatctaccaa tcaacgggca agcctgcctt aagcttaagc
    22741 taaaatcaag tgaaaacaag gggattttgg ctgcacagct cctagattat ggcaagaaaa
    22801 aacgctttgc tgatatacct gctattcttg agctagacag cattgacaac gggcagcagt
    22861 ttgcacgtga agcgctcaag gagcttccct tcaaggacag cccataccgc gttgtcacca
    22921 agggtgtcct aaacctacag caccgcagcg acctattgac cattgaggat attccaaatg
    22981 accaatggat gaccatcacc ttccacttgc agccaaccat ctatcatatg gccaagggag
    23041 acaccctaag agtcgttctt tacacgactg attttgagca tacaatccgc gacaatagca
    23101 actatgccct aaccctagat ttggagcaat cctatctcct aatccctact gatgaggagg
    23161 aataaatcaa agcgcatcaa aaaagcctga gatcacaatg agctgcaccc caatcgttag
    23221 atcctttgtc taactgttgg agtacagctc aaagctctag gcttttttaa ctattttgaa
    23281 acctttttac cagcctcagc accagaatgc aggctgtaga cggactcgat atgaatcaag
    23341 cctgctgcct ttggtgcgcc catcttgcct tctgcccatt ccttggcagc ctcaaagaca
    23401 ggaccctctg taatgatttc cgcacgccct acaaagcgat aaccacgcaa ttgctcgcga
    23461 ttgacataag cgacctcaat tttaccatta gcctgaatat tagagcaggt ttggccgcca
    23521 gtattttcat tataaaccaa ggtttcatcg tctaacagtc tcatcgaacg cttagggcca
    23581 atattaggat taccctcatt atctacagtt actaccattg ctaattgctc agcaatcatt
    23641 tctttcattt cttctgttaa catataatct cctcttaatc gtttctatag tcagctgact
    23701 acgctttgat tatagcacag ttaagcagaa aagccgacaa aaataggtta gcttaaaaaa
    23761 gttttacagt ttacttaaga ttagaatgat tctcgctatc tagccatcac ccttgatcac
    23821 agtaaaaagg cgattagcaa gcaagcactc tttatttcat aaaatccgaa tcgtcgccca
    23881 aaaaaaatat catcaactga tatggtcaat gcctctgcaa tacctcttaa tttttcatac
    23941 ttagctcgcc taagcttttg cacatccttt tcatatctgg ctagtgtcct aacagaaatc
    24001 ccagttaacg ctgacagttc cttttgggtc tttttttgag caatcctcaa ttcctttaac
    24061 gttgcttttg acaatatttt ccctccgcct ctcatctcag gtaatattaa tgacagatga
    24121 caagtttatt atagacttcg gtttttatga agtcaagtct tttatcgcac tttccccact
    24181 tctttttcta aatcttttga tttagcttga tttgtggtat catatcctat atagaaataa
    24241 aggagaatgg aaatgtccga aaagaaaaca ttttttgcaa ctaatttaaa atatcttcgg
    24301 ctaaaaaaga atatggaaca attagaactt gctaaccttt taggacgaaa aagctcttcc
    24361 tcaatcagcg aatgagaaag aggaaagtac actccaaaat ctggtctcct gagtgacatt
    24421 gctgccatct ttgatgtcag cctgacagac ctcatggaaa aggatttaac actggaaaat
    24481 aagggagtga cttatcagct tccccaaaga gatttagtaa tgatttcaga gcagctatct
    24541 gaaaacaatt ataacaaatg gctggatttt ggtcaggatc tcttatctca tcaggataaa
    24601 gaagaaaatc acaagccaag caaataaaga gcctcacacg tcttattctc atcaagtttc
    24661 gaaaaatcac ctaccactca agcacacaaa aagccttggc agggcttcta agcataagaa
    24721 agctgtatca tatcaatacc tcagggacca tgatatgata cagctttttg tatctcactt
    24781 ttagacaagg tagccacata aagcttgcag atgacctacc tctgtattag ctaccacaac
    24841 caacagctag ctagactggc aggccctcta taagcctcag cggattatct aagcactccc
    24901 aacagctcca acaaaataaa gacataacca ataccattat ttaagatatg ggctactgtt
    24961 gaaaaataga tattcttctt ccaaacataa actaagccga gcaaaagtcc cagtccacca
    25021 tacacaacga tggaagatag ctcgctgaag gaatagatat gaaccaagcc aaatagcaat
    25081 gatgatccca acaatcgagc cagcagcata cctgtgcctg attggccctc accgattaaa
    25141 atcttgcgga aaataagctc ctcattgaag ggaccaataa tactcaccac cagaataaag
    25201 atcactgtct cgaagccctc actagcatta tagcgattag ctaaaacagc tgcattgctg
    25261 ctctcttcta aaggaaggct actgagcaaa atatttgcaa cataaagcac tgcaaaaatg
    25321 accaagaccc acaaggtatt tttgacccat tttgttgaaa actgccgcca gtccctctga
    25381 taatctgctc gataaagcca acagatccca agtgcaaaaa tcagcagatg tctcccgtaa
    25441 aataaaaagg tattcaataa aggcggaagc tcaatcacat tgctaacttg tctataaaga
    25501 tacacagcaa tgatatatag catgaccagt acagctgcac gatgacgttt gatggtatcc
    25561 aattactctt cctcaattct aataattgtc agattagcta ggctatattg ccatcagcta
    25621 atcttgatct taaatgtgac taatttacaa gcactcaact tttgaatcgg taaagctgac
    25681 agacagccct accctagctt caataaagct atcttccaat agtccttgcg ctcatcagaa
    25741 ctgtcaaagg cctgacccag ctgagtcaac agacttatcc agtcaacatc acacagaaca
    25801 agaccatctt accatatccc tgccaactat aaaagcccct aacctgacct atttgactac
    25861 taacagcaaa aaagcagctt aaaaacacca atcagacgcc accaaggact cttgatcagc
    25921 gcagctcgca cagacacctg aaaaatgaca gacaagcctc ttaaaagcac ctcagcaagc
    25981 tgagccaacc cttcacagaa tagacaaaca acaagagcta agtcaagacc tcaagctagc
    26041 agattacagg cagagacgct tgcaaggctt acccagcaaa aagcaacaga ctgataaagg
    26101 attcacacca cacagccaca agtcaagcag ctagcccaaa caaagcactg ctcaccaaat
    26161 cctactatgc tttctggtag cccttatcca ttcaaaatcg tatccaaggc ttcttgatat
    26221 tgcttgtctc gcaattctct gatcacctgt gataaatact ctgcctgata catcacaaag
    26281 tcaaaattga aatccagaat tttggtgttc tcattcaatg acagcctctc ctcgataaaa
    26341 gcagtcatct cagctgttgt cacaatcaag tcaaaatcag ttctccaagg caattcagcc
    26401 tctgacaaaa tattaaaacg atagaccttt gcaacacaag gactcacctg ttgcatgacc
    26461 aagctatata aaatatcaat gtttttcttg ttgatttcga tcactgctat ggctaaaggt
    26521 ggcagacctt ctctaacaag ctgttccagt cgcgtgcaaa gcaaatgcaa attagagcct
    26581 gtcagccgac caacaccaga aacccgctct gcccagctat taatcatcag ctcgatacga
    26641 ttggccaaga gcttactgcc ttgatattcc tccgcataat aatatttttg cgggataaag
    26701 agcgacaaat caaacaaggt cttacgaaaa taaggaatca aggtctgaat acaagccttg
    26761 tcaaaggcga tatagtggcc aaacaattga cgcagctcac ccagcagctc ttggtaagca
    26821 ggatcctcct gaatgatcgt caataaggcc gaagaatcct cctcagacca ttgtgtgatc
    26881 gaaaaagagt tgttaaccgt caaataaacg agaaaaatat aatcaatctc gctactggga
    26941 aagtccatat caagcaacaa tttcccctca cgcttgaaaa agtcctccaa atacccataa
    27001 agcgccaaag actttaagcg tttaaaaatc ccctcctgag gaatcgcaac gtcaaactct
    27061 ccacgcttcc aagatagcga caagagcaca tcaaaaaagc gaaacttctt atccagtaac
    27121 gggtgaggcg tttgttgctt tttgatcgaa aagataaagt catgcacaat atccagatca
    27181 tggtcagtca gctcatagat gacaatcccg tacttatcat gcaataaagc aatcaaatag
    27241 cggatacgcc actcctcacc aacaacacta ttatcctcta aggccaagcc gcactcctca
    27301 acaaagggct tcatgtgctg aatcagccga taagctgacg gtgtggaaat aaaatgctcc
    27361 ctagcaaagc ctgagacaga tttgacctta tagcaaggtg ccttgatcaa gagaaattta
    27421 agaatgtgca gccgtaccga ttggcggtaa atcgtcttca aaaacggttt gccccttttc
    27481 aaaacggtgc agcggacaat ggtgctatcc cactcaaagg cgatatctcc ttggaaaagc
    27541 tcctctaatt ggtggatata gcgctttatg ttagctaggc taaagcccgt cttttgctga
    27601 atggcgtgga aactgatcct ttttttacca agtagtatgg tcagcagcaa agcctgatga
    27661 ttaatcactg gttccaaata ctcttcaagc aaaacacttt ctcctcctta aaccatttcg
    27721 ttagcgtcat tatcataaca atttttacca aaaaagtgat gaaaaatatt taatatcagg
    27781 acgatttttc tgatagcctt tattataaca caaaagctca aggcaggtaa aacgataaag
    27841 aaatcaactt aaaactatga cacagtctca tctcatatga tatagttatt caggtttcct
    27901 aatggaaaac atattaacaa cttaataatg gagagaagaa agttgaaaac aaaatcattt
    27961 agaaaggtac tgacaacgtc agctacctgt attgtgctgg caacaagctt tgccggagga
    28021 accctaagag tctgggcaga gcagctttat tatgggtgga atgatggaac gagacaaagt
    28081 tcgccatatt ttttgtacgt atcgcctaaa aatgctccaa agcgtgaatt aaaagacgag
    28141 tatgttgttt attgctttaa caaaaaattg tattggccag atcaatggga atctatatac
    28201 agcaatttta atgacatcag atctccatat aacgatttac ctgtatatga gaaaaaacta
    28261 ggatatgatg gtatatttaa acaatatgct ccagattaca aaaaagatat tagtgatatc
    28321 gcaagtgctt tggtggcagt tttaagtaat ggatacccca ctaacaagtc acaactatca
    28381 actagctacc atttaaataa tgattcttct agaaaagtta ctcaattagc catttggtat
    28441 tttagtgata gtttaacaaa agaatacctt aaagatacgg gtggttataa cttaaacgat
    28501 atggaaaaaa aagctttaga ttttttaatc agtaaaggag aggattctaa gcttaaatca
    28561 gagcagagta attactcatt ggatatttat gtttatcaaa gtggcgggca tgaccatatg
    28621 aaagattacc aaaatcttct cggctctacc ttaattccta aagaaccgct aaagcctcag
    28681 ctaggtggtt ttagtggaca taatggaaat ggattaagcg gccttgaagg aggatcatca
    28741 ggttcacaag aaactaatga agatggtaag aaaggactta taggtttcca tggaggactc
    28801 tcaggaagcg agggcaaacg agatcctttc caggattgaa gggtgaggct ggtgcacctg
    28861 atacacctca aaagcctaat gacccattgc aaagtcttga aggtggtaac tctcctatcg
    28921 tagaacaaaa ctatggtagt actgagggat atcatggtca atctggcatt cttgaggaaa
    28981 ccgaagacac taacccacct ggtatcattt taggtggctc aggaaatgtc gaaacgagat
    29041 cctcatctga tggggcttgg cggtggtcta gctggcgaat caggagaaac gacacctaaa
    29101 ccaggacaga ctggtggtca tggaccaatc atcgagacaa cagaggacac acaaaaaggc
    29161 atgtctgggc aatctggcgg cactatcgag tcagaaaaca ccaaaaagcc tgaggtcatg
    29221 attggtgggc agggacaaac catcgaaaca acagaggaca cacaaaaagg catgtctggg
    29281 caatctggcg gtactatcga gtcagaagac actaaaaaac ctgaggtcat gattggtggg
    29341 cagggacaaa ccatcgaaac aacagaggac acacaaaaag gcatgtctgg gcaatctggc
    29401 ggtactatcg agtcagaaga cactaaaaaa cctgaggtca tgattggcgg tcagggacaa
    29461 atcatcgact tctctgaaaa cacgcaatca ggtatgtctg gacagtctgg agacactacg
    29521 gtcattgagg ataccaagaa gtctgagata atcattggtg ggcaaggaca aatcatcgac
    29581 ttctctgagg atactcagcc gggtatgtct gggcaatctg gaggcaccac aattgtcgaa
    29641 gacaccaaga agccgacacc taagcctaaa cctgcacctg cgccaattgt taatgacgaa
    29701 aaacctaaca aaggcactca gctcccacag acaaatgata tgaagcaact caccctaagc
    29761 atcatcggtg caatgtcaat gctgcttgtc ctatgtctgt ctctattcaa gcgaccatct
    29821 aaaaaagact aagcaacact gacaagtgat cattattgta cggacgttta caggcgggct
    29881 ttctgccctc ttaaaacacc gtacaacaac aaaacggtct aaatagaaat atccctcaag
    29941 ggttagacaa tcgctctagc ccttggggct ttttttgata cttataatag aagagagcaa
    30001 gcagtgacac tttctttttg ccctatatct gctaacacta gcggtatgtg cagttaccat
    30061 aggctatcaa ctcgtcgtgc aactctagag aaaagctgat acaaaaaaca agcaccagcc
    30121 ttgctgctga tgcttgctcc ggacttactg ataagccttt gtgatgtcct agctttataa
    30181 ccatatgcct attacctaaa ggtctagtct cctaatggtg ggctggctgg taaaagcaag
    30241 gagaaacagc tcccctttcc aagctggctc tcaacagcaa tatccccacc tagttggcga
    30301 gctaactgcc tagcaataga gagccccagc ccatgaccac cagtcttcat attgcgagag
    30361 gcctcaacac gatacaggcg cttgaaaatc aaaggcaggt cctctttttt gatcccttgc
    30421 ccctgatcaa taacatcaat gcgaatggac tgctcctgtt gataagcatg aatcgtcaaa
    30481 gccgtattag cctttgaata tttaagcgca ttgctgacta aattcagcat aatccgagac
    30541 aaagcatcat atcggctgct gatcttaacc acctcttttg ccacctcaat atgaacggag
    30601 cgtttttcct gctctaaggt caattgaaat tcggatagca tgtcaatcaa tagcttttca
    30661 agatagatga tttgaagctg ctgcttgtcg tcttgctttt gatcatttaa gctgaccata
    30721 tgcaattctt caactaattg attcaaacgg ttggtctgtc gtgagatggt gtttagatag
    30781 tgcctttcct cttcccttgg aataacgcca tctaaaatcc cctctacagt tgcttgaata
    30841 gaggtcaagg gtgtcttaat atcgtgcgac agctgagcaa tcatcatgga tttctcatgc
    30901 tcactctcac tcaatgactc aaagctgacc tttagctctg aggacatctg attaaaggct
    30961 tcctctagat ctttaaactc caaaggacac ttgatgagct gaccactatc aaagtttctt
    31021 tcagaaatag cctgtatctt tttctttagc cttttaagcg atgaaaaaac attactcaaa
    31081 aggatcatat tcacaattcc tccggctact gaagcaatta gagctattac taaaatatat
    31141 gaaatatcct caatggtaat gagcatttgg tttaacccaa caatcaggcc tgcaatagta
    31201 atcagcatag acattaaata gccaatgaca atgtacgttc ttaatcgcat gctacccctc
    31261 taatttataa cctagtcccc aaaccgtttt aatggttggt gtttgctcgg tactgtattt
    31321 tgccaagtca ttgcgtaggg aatgaatgtg aacatttaag gtattggtat catctaaata
    31381 ctcctcctcc ca
//
LOCUS       DARYXZ010000025        31131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYXZ010000025 DARYXZ010000000
VERSION     DARYXZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TV186_001036"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TV186_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL1532439.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TV186_001037"
     CDS             complement(1584..2021)
                     /locus_tag="TV186_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL1532440.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TV186_001038"
     CDS             complement(2008..3234)
                     /locus_tag="TV186_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1532441.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TV186_001039"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TV186_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL1532442.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TV186_001040"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TV186_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL1532443.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TV186_001041"
     CDS             complement(5505..6662)
                     /locus_tag="TV186_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL1532444.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TV186_001042"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TV186_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL1532445.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TV186_001043"
     CDS             complement(7553..8392)
                     /locus_tag="TV186_001043"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL1532446.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TV186_001044"
     CDS             8708..10276
                     /locus_tag="TV186_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1532447.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TV186_001045"
     CDS             10269..11009
                     /locus_tag="TV186_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1532448.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TV186_001046"
     CDS             11357..11473
                     /locus_tag="TV186_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL1532449.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TV186_001047"
     CDS             complement(11997..12887)
                     /locus_tag="TV186_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL1532450.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TV186_001048"
     CDS             complement(13150..14814)
                     /locus_tag="TV186_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL1532451.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TV186_001049"
     CDS             complement(14814..15179)
                     /locus_tag="TV186_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1532452.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TV186_001050"
     CDS             complement(15331..15519)
                     /locus_tag="TV186_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL1532453.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TV186_001051"
     CDS             complement(15979..16344)
                     /locus_tag="TV186_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532454.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TV186_001052"
     CDS             complement(16934..17815)
                     /locus_tag="TV186_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL1532455.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TV186_001053"
     tRNA            complement(18018..18103)
                     /locus_tag="TV186_001053"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TV186_001054"
     CDS             complement(18158..19084)
                     /locus_tag="TV186_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1532456.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TV186_001055"
     CDS             complement(19444..21057)
                     /locus_tag="TV186_001055"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL1532457.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TV186_001056"
     CDS             complement(21331..21897)
                     /locus_tag="TV186_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL1532458.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TV186_001057"
     CDS             complement(22164..23447)
                     /locus_tag="TV186_001057"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL1532459.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TV186_001058"
     CDS             complement(23796..25205)
                     /locus_tag="TV186_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1532460.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            25656..26495
                     /locus_tag="TV186_001059"
     CDS             25656..26495
                     /locus_tag="TV186_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL1532461.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(26591..27151)
                     /locus_tag="TV186_001060"
     CDS             complement(26591..27151)
                     /locus_tag="TV186_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL1532462.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(27164..27637)
                     /locus_tag="TV186_001061"
     CDS             complement(27164..27637)
                     /locus_tag="TV186_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1532463.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(27643..28392)
                     /locus_tag="TV186_001062"
     CDS             complement(27643..28392)
                     /locus_tag="TV186_001062"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL1532464.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TV186_001063"
     CDS             complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TV186_001063"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL1532465.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            29318..30682
                     /locus_tag="TV186_001064"
     CDS             29318..30682
                     /locus_tag="TV186_001064"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL1532466.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
BASE COUNT         9264 a         7451 c         5668 g         8748 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat actgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttggcgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat ttttttaatt tttatttcct
    25381 ttgctaaagc ctctaaaacc aatcaaaata atgttgcata agtatttgcc ttttatttat
    25441 ctcataatca gactcattcg ctctaatctt ttgcacatgt taatgtcatt tatttgcaga
    25501 cctacgcaac caattgcaca gagctttgtt tccttcgtca gaaaaacctc aataaaacat
    25561 aaacaagaag ccattactct tcttgataat gtttggtgat ctattttcaa ccaggacttt
    25621 ttttggtaaa ctagctacga tagaaaggag ttgccatgac gtttatatta acatacttta
    25681 atcagctaca cctagaaaat atcatggtgc ttgtgttttc taaattagtg tcaatcacct
    25741 tattattgat tttctttgtg atcttcaaaa aaatcacgac agctttattt gaaaaggcaa
    25801 tcgccaagtc attttcctat tcaagacaaa ctgaagcaag gaaaaaaacc ttatccaagc
    25861 tccttcacaa caccctaaat tatgttttct attttcttct catctattgg attttgagcc
    25921 tacttggtat tccagtatct agtcttttag caggagcagg aattgctggt gttgctattg
    25981 ggcttggggc tcaaggcttc ttgtctgatg tggtcaatgg cttttttatt ctgtttgaaa
    26041 atcaatttga agtaggagac accgtcacca ttgcaggcat tgaaggaacc atctccagcg
    26101 ttggtattcg aaccactcag gtgcgaggct ttgatggcac actacatttt attcccaacc
    26161 gcaatattac agttgttagc aacaaatcac gcggcaatat gagagctttg atcgatattc
    26221 cactttattc ctcaaccgat ctagagcatg tgacccaaat catcaaggct gtcaataagc
    26281 gagaggtgcc aaatttccca caaattgtcg gacagcccaa cattctagga ccacaaacca
    26341 atcccaacgg acaattcacc tttcgcgtta gcatttttac tgaaaatggg cagcaattta
    26401 cgatttacta tagcttttat aagctctatc aagaggcctt actaagggag ggtatcaagc
    26461 taccaactgc atctgccata tcacccttag cctagcagta aaaaccattg ctttcttagc
    26521 atacaaaagc cctatcccgc agccaggtca tcagacttag actgctagat agggctattt
    26581 cttttggctc ttatttccga ataggatcag gctgatacct ggctcttaca ccaccaatta
    26641 atttgggccg acttgctaag gcagtcacat gagcaccacc aagctctcgc tgaataggca
    26701 caagcggcac ctgtacacgc ttaacatgca taccaattga ggtatctcca atgtcaaggc
    26761 ctgcatgagc agcaatggct tcaacctcaa ctggctgctt catgtatttg aaggctgcta
    26821 attgaccact tcctccagca tgcaagctag gcagcacatt gactatttct agccgatatt
    26881 cttcagcaac actttcttct aataccaagg cacgattaat gtgctcacac ccctgaaccg
    26941 ctaaatgaat ccctctgaac gacaattcct ccaatataag cttcacaata acctcgccca
    27001 cctctaagct agaatgctgg ccaatacgac caccaagtac ctcgctagag gacagcccta
    27061 agacaaacag ttgccctttt ttgatagcac tacgctccac aatatcaagc aagatagagc
    27121 gtgcttcttc tctcaatact tttaaattca ttgaatcacc tgcttaatca tctgacactt
    27181 tgaccagctg ttttttgacc cctaaataca gcagatagcc tacacctatg ccaagggtat
    27241 tttgagcagc attccccgaa atttctgaaa tagcagcgcc cataccatac attggaatag
    27301 ctgcaagaaa atacagacca accattatca cagaagcaag gcccacgcca agaaagcgat
    27361 gcctgccagg caagcctgct aagtagccct gagccccatg agcaacaaga ctaatcagca
    27421 tccaattggg gtaacctgag atcaaatcaa gcaaaaaagc tgataagccc ccaacaagca
    27481 taccctcctt tttcccaaga gaaaaggcag tcacatacac ccctgcatct aaaagactta
    27541 aaaaacctgt cggcgtggca atactcacaa acctgcccag gacaactgtc agggcagtca
    27601 agatagacac aagagctagc tctcttgtct gtttcatatt tatcataaga caactccata
    27661 atcatttgac tgttgaatgg cttcaaaaac aaggtcttta gcctgctcaa cagccctaag
    27721 cggtgaatat cccttagcta aataagcagc aattgcagct gcaaagctac agccagcccc
    27781 actgttttgt ttggccaaga ctggcttttc taaaaagcac agggtttttg cgtcataaaa
    27841 tagatctagg gcaactcgtt gatcaaaacg attcccaccc ttgatcacaa ccctcttagc
    27901 ccccatctca taaagctttt ttgccgcttc taccatttgc tccctgctat taatagcaag
    27961 ccctgccaag cgttctgctt ctcttaggtt gggagtaatc actgctgtta agggaaaaag
    28021 agagcgcaaa gcctgtgtca tttccacaac tgtctgatct tgattttcct taaatactaa
    28081 aacaggatct aaaacaacag ggatatcctt ttttagctct aaaaacaggg ccacctgctc
    28141 tgctatttca ggtcttggca aaagaccaac tttgattgcc tgaaaaggaa tagctgctaa
    28201 gctagacaac tgctttgcca gcaaatcagt cgcaacaggg tgaatgctga aacctttagc
    28261 atcacagctt gttaagcagg tgatagctaa aaatgcaaag ctatcgagct gatgaagcac
    28321 tgccaaatca gcctgcaaac caccaccgct gaatatatca ctcccagcaa tcgttaatac
    28381 cttattcttc ataaatgatt tccttcaaat aaagaccatt accagccgct gtcggtccag
    28441 ctagctgccg attcttactc tctaaaacga gcctgatttg ttcaatgggc aaccgaccat
    28501 tgccgatctt aagcaaggtc ccaaccatat ttctaacctg cttataaaga aagccattcc
    28561 ctgaaaacgt aaaaacaaga aaaccagttt tagggtcctg agtgagggta gctgctgtaa
    28621 tggtacgaac cttattttta acagaggttc ccgcagctgt aaagcctgta aaatcatgcg
    28681 tcccaaccaa atccttaatc gcagcctgca ttttcgcaat atctaaggga taagggtaat
    28741 gggtcgcata atggcgcatc ataggatttt taggacgacc aatatccact aagaattcat
    28801 aggttttgaa atgcttatgg tagcgagcgt gaaaatcatc tgctgcaatc tccagactga
    28861 tcacatcaat atcatctggt gtctgggtat caagtgcaaa gcgaagcttt tcagggtctc
    28921 ttttttgctc caaatcaaag tgaatcactt gaccataagc atgcacacct gcatctgttc
    28981 taccagctcc atgaatctgt atcccttgac cacctgtcaa tttttgcagg gtcttttcaa
    29041 tctcttcttg taccgtacgt gcctgacttt gtctctgaaa accagaaaat aaggtcccat
    29101 cgtaggaaat aattgcttta tatcttgtca tgctattatt ctaccatttc ttccagccat
    29161 cagaaaagag catttacggc ttttgtcccc atacagtttt cgattagctt tgataatcaa
    29221 gcttgatttg acgccaacag gcaaaaaaag gctactgaca aggactagct tttctgctat
    29281 aatttctcta atattcaata agtagactgg agagcaaatg aaggtaacaa aatttggcgg
    29341 cagctcctta gcatctgccc agcagttaga aaaggtcttg gctattatca aggacgatcc
    29401 tgagcgtaaa atcatcgttg tctccgcacc aggcaaacga tcccctacag acacaaaggt
    29461 gactgatgca ctcattgctt attacaaagc ctacgtctca gaccgtcatt atcacaagca
    29521 tttggaatgg attatcaatc gttaccaaca aatctgtaat gacctaactc tagatagcaa
    29581 aatcatcacc caaattaaag cttccttaga gcaattggca cggcttccaa aagaacataa
    29641 tccctattta tacgatacct ttcttgcggc cggtgaggac aataatgcta agctagtagc
    29701 tgcctacctc aaggcaaatg gcttaactgc aagctatctc caccccaaag atgcaggtct
    29761 aatcgtaagc agtgagccac agcatgcacg tcttcttcca atcagttacg ataagctaga
    29821 ggccttaaag gatcatgatg acattcttgt tattcctgga ttctttggtg tgacaaatga
    29881 aaaccagatt tgtaccttct cacgtggtgg ctctgatatt accggctcca ttattgcagc
    29941 aggagtcaca gctgacagct atgaaaattt tacagatgtc aatggcatct ttgctgccca
    30001 ccctggtgtt gttaagcagc cacagacgat cactgaatta acctacagag aaatgcgcga
    30061 gttagcctat gctggctttt ctgtcctcca tgatgaagca ttaatccctg cttaccgagg
    30121 gaaaatccca atcgtcatca aaaacactaa caatcccagc cacccaggta caacaattgt
    30181 tcttgagcac cagaggaaat ccaatcccgt tgtcggtata tcaggtgatg atcactttgt
    30241 cagcattaac ctatctaaat acctcatgaa cagagaaatt ggatttgggc gcaagctcct
    30301 tcagatatta gaggacctca atatcagatg ggagcacatg cctacaggta ttgatgacct
    30361 atcaattgta cttagagaaa gagaattgac ccccatcaaa gaagaagaaa tccttcgcag
    30421 acttgtccag caattagagg ttgatgaggt gtccatcacc aggaaccttt ctattatcat
    30481 gatagtcggt gaaaacatga aaagtcatat tggtgtcaca tctgccgcaa caaaggctct
    30541 atctgaacat catatcaata ttgctatgat ttcccaaggc tcaagtgagg tatctgtcat
    30601 gtttgtcatc aatagcaccg atgaaaaaaa ggccattaga gccttatatc aaaccttttt
    30661 tagccctgat cgacccctgt aaagctccat ataacatctc ttgttaacac caagcttcaa
    30721 aaacagctca caagctagac agtactccta gcctatgagc tgttttgatg atctaaaact
    30781 atcaagatta agcatcggta gtaacgactt aatatgctca cagctatcat aaactctagc
    30841 tttaccttat tgaggaaaag aaaaccagtt ttcacctcag ctaagattaa caacaagcga
    30901 ttaagcactt gctaaaaaca gatagacttc aaaagtgaga catatgtata atttctacca
    30961 gatctaaata aatatagcag cagagcaccg agtttaataa gccatttctg acatgataaa
    31021 ctcgccaagc tctccacaga tcaagatttg ccttatcaat tgatacaaca gccagcattc
    31081 tcaaagatgc acaagatcca tcacagtcta gccatctccc tgcacagtaa g
//
LOCUS       DARYXZ010000026        30531 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYXZ010000026 DARYXZ010000000
VERSION     DARYXZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30531
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1435)
                     /locus_tag="TV186_001065"
     CDS             complement(<1..1435)
                     /locus_tag="TV186_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1532467.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TV186_001066"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TV186_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL1532468.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TV186_001067"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TV186_001067"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL1532469.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TV186_001068"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TV186_001068"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL1532470.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TV186_001069"
     CDS             complement(5344..6630)
                     /locus_tag="TV186_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL1532471.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TV186_001070"
     CDS             complement(6772..7143)
                     /locus_tag="TV186_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL1532472.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TV186_001071"
     CDS             complement(7130..7402)
                     /locus_tag="TV186_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL1532473.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TV186_001072"
     CDS             complement(7433..8944)
                     /locus_tag="TV186_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL1532474.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TV186_001073"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TV186_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL1532475.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TV186_001074"
     CDS             complement(12410..12979)
                     /locus_tag="TV186_001074"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1532476.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TV186_001075"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TV186_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL1532477.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TV186_001076"
     CDS             complement(14337..14702)
                     /locus_tag="TV186_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1532478.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TV186_001077"
     CDS             complement(14823..15020)
                     /locus_tag="TV186_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL1532479.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TV186_001078"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TV186_001078"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL1532480.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TV186_001079"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TV186_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL1532481.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TV186_001080"
     CDS             complement(17976..18749)
                     /locus_tag="TV186_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1532482.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TV186_001081"
     CDS             complement(18869..20092)
                     /locus_tag="TV186_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL1532483.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TV186_001082"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TV186_001082"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL1532484.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TV186_001083"
     tRNA            complement(21081..21154)
                     /locus_tag="TV186_001083"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TV186_001084"
     tRNA            21435..21506
                     /locus_tag="TV186_001084"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TV186_001085"
     tRNA            21539..21612
                     /locus_tag="TV186_001085"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TV186_001086"
     CDS             complement(21873..24458)
                     /locus_tag="TV186_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL1532485.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TV186_001087"
     CDS             complement(24581..26200)
                     /locus_tag="TV186_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1532486.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TV186_001088"
     CDS             complement(26280..27152)
                     /locus_tag="TV186_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1532487.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TV186_001089"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TV186_001089"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL1532488.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TV186_001090"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TV186_001090"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL1532489.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
BASE COUNT         9430 a         6201 c         5600 g         9300 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa atagacatga aatattgtga a
//
LOCUS       DARYXZ010000027        30046 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYXZ010000027 DARYXZ010000000
VERSION     DARYXZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30046
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..134)
                     /locus_tag="TV186_001091"
     CDS             complement(<1..134)
                     /locus_tag="TV186_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1532490.1"
                     /translation="MKSIIEHYQARPLGEERCYAVCLPLIWQEGRWQVLYEIRSQHIS
                     "
     gene            336..662
                     /locus_tag="TV186_001092"
     CDS             336..662
                     /locus_tag="TV186_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL1532491.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
     gene            649..1074
                     /locus_tag="TV186_001093"
     CDS             649..1074
                     /locus_tag="TV186_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532492.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            1093..2148
                     /locus_tag="TV186_001094"
     CDS             1093..2148
                     /locus_tag="TV186_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1532493.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(2252..4534)
                     /locus_tag="TV186_001095"
     CDS             complement(2252..4534)
                     /locus_tag="TV186_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL1532494.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            4666..5199
                     /locus_tag="TV186_001096"
     CDS             4666..5199
                     /locus_tag="TV186_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1532495.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TV186_001097"
     CDS             complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TV186_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL1532496.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(6541..6813)
                     /locus_tag="TV186_001098"
     CDS             complement(6541..6813)
                     /locus_tag="TV186_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL1532497.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TV186_001099"
     CDS             complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TV186_001099"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL1532498.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TV186_001100"
     CDS             complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TV186_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL1532499.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            complement(8676..10652)
                     /locus_tag="TV186_001101"
     CDS             complement(8676..10652)
                     /locus_tag="TV186_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL1532500.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TV186_001102"
     CDS             complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TV186_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL1532501.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            complement(12641..13105)
                     /locus_tag="TV186_001103"
     CDS             complement(12641..13105)
                     /locus_tag="TV186_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1532502.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TV186_001104"
     CDS             complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TV186_001104"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL1532503.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            14715..15386
                     /gene="sdaAB"
                     /locus_tag="TV186_001105"
     CDS             14715..15386
                     /gene="sdaAB"
                     /locus_tag="TV186_001105"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL1532504.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            15398..16270
                     /gene="sdaAA"
                     /locus_tag="TV186_001106"
     CDS             15398..16270
                     /gene="sdaAA"
                     /locus_tag="TV186_001106"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL1532505.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            16304..16939
                     /locus_tag="TV186_001107"
     CDS             16304..16939
                     /locus_tag="TV186_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL1532506.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(17000..17611)
                     /locus_tag="TV186_001108"
     CDS             complement(17000..17611)
                     /locus_tag="TV186_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL1532507.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(17867..18676)
                     /locus_tag="TV186_001109"
     CDS             complement(17867..18676)
                     /locus_tag="TV186_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1532508.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(18669..19511)
                     /locus_tag="TV186_001110"
     CDS             complement(18669..19511)
                     /locus_tag="TV186_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1532509.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(19487..20326)
                     /locus_tag="TV186_001111"
     CDS             complement(19487..20326)
                     /locus_tag="TV186_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1532510.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TV186_001112"
     CDS             complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TV186_001112"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL1532511.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(20884..21888)
                     /locus_tag="TV186_001113"
     CDS             complement(20884..21888)
                     /locus_tag="TV186_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1532512.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(21938..23221)
                     /locus_tag="TV186_001114"
     CDS             complement(21938..23221)
                     /locus_tag="TV186_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1532513.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(23223..24467)
                     /locus_tag="TV186_001115"
     CDS             complement(23223..24467)
                     /locus_tag="TV186_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1532514.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            24682..25095
                     /gene="yaaA"
                     /locus_tag="TV186_001116"
     CDS             24682..25095
                     /gene="yaaA"
                     /locus_tag="TV186_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL1532515.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            25097..26206
                     /gene="recF"
                     /locus_tag="TV186_001117"
     CDS             25097..26206
                     /gene="recF"
                     /locus_tag="TV186_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL1532516.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(26271..27134)
                     /locus_tag="TV186_001118"
     CDS             complement(26271..27134)
                     /locus_tag="TV186_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL1532517.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(27305..29734)
                     /locus_tag="TV186_001119"
     CDS             complement(27305..29734)
                     /locus_tag="TV186_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL1532518.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
BASE COUNT         9239 a         6557 c         5511 g         8739 t
ORIGIN      
        1 tgagagatat gttggcttct gatttcatat aagacctgcc atcgcccttc ctgccaaatc
       61 aaaggtaagc aaaccgcata acatcgctcc tcacccaagg gcctagcctg ataatgttca
      121 ataatgctct tcatctgtcc ttctccttat catatccatc actaagctac tttcatagta
      181 taaaatagta atcctttggt caagaaatgg ctccgattac tctctatgat atataaaatt
      241 tttatatata aaatattgac atattaaaac agaaactcta tacttaatat ataaaataat
      301 tatatataaa tacgaggcag gaagggagta accagatgta ttttccagta tctgctacct
      361 tgattgaatt tttgatttta tctattgtcg acaagcatga ttcctatggt tatgatatca
      421 gccaaaccat taagcttgtc gctaatatca gggaatcaac cctataccct attttaaaaa
      481 agctagagaa atcagactat ttaactacct atagtcagga acatcaaggt cgcaagcgta
      541 actattacac cattacagcc aaaggcgaaa agcagctgat tttcttaaag gaagaatggc
      601 aaagctacaa ggccacccta gatggcatta ttgaagggag attaaggcat gacaagagat
      661 gaatacctag cagagctaga caaataccta cgaaaattac ctaaagcaga ttattatgaa
      721 gctgctgaga actcaagtca gctagaactt aacgacggca gtatcaaaga ctcttctatc
      781 actgtagctg atacaaaaga agaaaacgac tatgactata cagacccctc cgagcttgct
      841 ataaatcatg tcacaatcaa ggagaaaaac acaattaatg gcggcgatat taatatcaat
      901 accacattag caaatccaag agatattgct tatcatgtca caacaagagg caacatcaag
      961 ctcagctctc gtttttcaaa cgccaagctt aacacagacg cagcaacagg agctacttca
     1021 tttcactctg acatagccaa tactgtcaat caaagcgacc tatcaattca ttaatcaagg
     1081 gaggatatca taatgactaa acaagatttt ctagacaagc taaagcagca gatcaaccat
     1141 ttacctcaaa aggattacca agaaatcatt gaccatttta cagagtattt tgacgaggct
     1201 ggtcctgacc atgaacaagc tattcttaaa gaactgggaa atccagagga cattgccaag
     1261 gagctattaa aagccttaga tctccccgaa aaaacagacg aagatgactg gacgaattgg
     1321 gaagttgaca acaaaacaaa gtcagaagca agctcacaaa agcttgagcc aatagttgac
     1381 attcgctata gtctgcttaa ccatgattta accattgaaa ctgctgacat tccttaccct
     1441 actatttcat acgatgataa tcgcatcaca ataagccaag atagtgacgg catgctcaat
     1501 atcattgaag actcagcagt acaaacaata cagtatggct ttcatttcct agaccgctgg
     1561 cttgcaaaat atcaacccat taccttgaca ctacctgtca accaccacct gaaaaaaatc
     1621 tctggagaaa gtgacaacaa cgatgtcacc ataaggcata tacattgtga tagcattgtc
     1681 tctaacactt acaatggaac gatttctatc agtcatttat cagatagcac tgtcaaccta
     1741 agcagcaaaa atgggaacat tattttagag cattgcaata tccagtctag taaatgtcaa
     1801 gccaaaaatg ctaacctcag ctgtgacaat agcaccctaa taaattgcca gctgaacaat
     1861 aacaatggaa acatcagatt agaagcaagt cagctaacag aaaccttcat tgaaaacaaa
     1921 aacggtaata tcatagggca gcagctgtcc ttttccaatg acatcactat catcaataag
     1981 aatggaatca ttgacatcaa ttgtcctaga gaaaacctca tctactatga cgtaaaggct
     2041 tcaaataata atggatttgt aacgattagt caagaagcag gtcgtcaaac accctttaaa
     2101 gcacagctta ccatttccaa taataatggt cttatctccg taagctaaac caaccataaa
     2161 aaaagcttct agaaagagct taaaccacaa tttctagaag cttttttatt atatctactg
     2221 tttaacgata acctgttatc tcagctatta tctaggacga ttgcttgtcc tttggacgat
     2281 aaatcagcac tcctatagcc ataaagctta acaaaaagcc aactaataca ctcgtctcta
     2341 aacctatctg ggcagttaat gatattgtct gacgaaggcc agagacaata taagacattg
     2401 gaagataagg atggagaatc tggaagatct gaccactcaa ctcaatagga taagaaccac
     2461 ccgcagcacc aacctgtagc aacagcataa ttaacgaagc aaaggcacca tatcgagcat
     2521 cccagctgac caatgcagtc actaaagcca tcaaggccca tccactcagc ataataaagc
     2581 ctaaggtctt gataccgtca ttagcttcaa agcccagcag ttgaagtgca gcgtaaagaa
     2641 taacagagcc aacggtcgaa atcatgccat tgatcagtaa tttttgcttt gcccaatccc
     2701 atctatcttt aatcggctta ccagataagg cctctgcaaa aataatattt gtagacaagg
     2761 caactaccat tagagacaca gcaatcatat aaggagccat gccaatacca ttggtcctaa
     2821 ccttatcctt gtccttctct gataacgcta ctggatcaga taccatatca gcattctggt
     2881 cctctaccca agccattgaa agctggtcag aagcttttga tagtgaggtc gttaagcttg
     2941 acagacctgt tgacagagtt gtcaagccat ctgtcaactg agagctgcca gaggagagct
     3001 gattggctcc aaaagctagc tgattagcgc ctactgtaag ctgctgtcca cctgctaata
     3061 attgactgga ttgatggtta agagctgttg cccctgtagc aagagtagac aggcctgctg
     3121 taagagcttc attcttagct gtcaattgat taaagccgcc agcaagagct tgactacctg
     3181 ataagagctg ggctgttgtc gctgagtgaa cagcccttaa accagttgaa agctctgaca
     3241 atgccttgcc tgtgctaggt aggatttgat cagcttgata agccagctga ttaacaagtg
     3301 ctttaaagtc cctcagttga tcagctacac cagcacttgt tgacatagcc tctagctcct
     3361 cagacatggc ttgcagtgat gtcaacatag cctttgctga tattgttact ttagttgaag
     3421 tattggaaat agctgagctc agctcctcct gctgctcaga gttgagacct tgataggtag
     3481 ctgtagcttg tagagcggct agctgattgt tcttgtcagc agtatcatct accacaagct
     3541 cctgcactaa acgcgtcata tcggctaaat gcttagcaat ggctcctgag tccacatttg
     3601 gtgccaaaga caaggaaaga ttggtcttta gctgctggat agcctgatta agctttggta
     3661 ggctagccat taaagcttga atattagctt gtttgtcttg agacagatca cttcctagag
     3721 ccaattgggt caagccagca tttaactgat tagcaccctt ggataaccga gaaacaccat
     3781 ctagatacgc tggcatatca gctgctagct gtcctaagcc cgcggtatca agctgaccaa
     3841 caccggctgt ataggcagct ataccactag atagattacc cgctccttga gacaagcgag
     3901 cacttgattc agacaaggtg ttcaaatgcc ttgacattag ctgactgctt gccctagcaa
     3961 ttactaagcc agcggctaat tgctgaccgc catttgaagc ttcctttaga ccagattgga
     4021 gctgatgcat gctcttaaaa acggaggtga tataggtctt ccttatattt ttagaaacag
     4081 cctctctcaa gtgattcata gcagattcac ccattttaga agcgataaag ctatggccct
     4141 tactagtttg atagctaaca atcagcttct ctggctgctg atctaatagc gtagtggcct
     4201 tttgtgacaa atcctttggc aacgtaatcg tcatataata acgacccttt tccaagccct
     4261 tttgtgcggt atctgcagcc acaaaatgat aatccaattc cttattttta gacatattgt
     4321 ctaccatatc gttaccaata gtcagtctct tgttattcaa gtaagcaggc ttatcctgat
     4381 tcacaactgc tacaggcaac tgatcaaccc gaccataagg atcccacatg gaccctaaaa
     4441 aggacaaatt atagagagct ggtactagag caaccccaat cattgtcact actagcttac
     4501 gatttttgat tattgctttt aatccttcta gcattatttt ttctccaaat agacatactg
     4561 ttcaaaaatt atgataaaat atattataca aataaagtga cattttacaa ggaaaaaata
     4621 aattttttag acataatgtc tacaagtgtt caaaaggaga taatgatgga tagccgcaag
     4681 cagcaaacca agaaggccat tcttaatgca atggtgagct tactaaaaac cgaaagcttc
     4741 gatgatgtaa caaccgttca gcttgctaaa atggcaggca ttagtcgttc tagcttttat
     4801 actcactata aagacaaata tgagatgatt gattactatc aacaaacctt ttttcacaaa
     4861 ttagaataca tttttgaaaa agaataccaa aacaaggagc atgctttttt agaagtattt
     4921 gaatttctca agcgagagca actactatct gctctgctat cctccaatgg tacccgagaa
     4981 atccaaagct ttatcattaa caaggttcgt ctgttgatca ctaccgatct tcaggacaag
     5041 ttcagtaagg acatcttgtc cccaaccgaa aaggaatatc gaagcatcta cctagcacat
     5101 gcctttttcg gtgtctgcca aagctggatt gctaaaggaa aaaaagaatc ccctcaggaa
     5161 atgactcgtt tcgtcttaaa aatgctatct aaaacatagt cctgcactaa tgatgtcaaa
     5221 tccagtacca aaaaacaact ttgtaaacta tttcttactg agtttataat gatctttatg
     5281 cctaacaata ccgacctcca atcgttagac ttttggtcta acctttgggg tcggtacata
     5341 aatcagctaa ccgctcaacc aaaaaagccc actgttgtgg gcttcttata atataaagtc
     5401 ttatcttaaa gcattttgtt gtagaattca acgacaagtg cttcattgat ttctgggtta
     5461 atttcgtcgc gctctgggag gcgagttaat gatccttcaa gcttttcagc gtcaaatgaa
     5521 acaaaagctg gacgtccaag agttgcttca actgcctcaa ggattgcagg aaccttcatt
     5581 gatttttcac gaacagagat gacttggcca atctcaacgc ggaatgatgg gatatcaaca
     5641 cgcttaccat caacaagaat atgaccatgg ttaacaaact gacgtgcttg acgacgagta
     5701 gttgcaagac ctaagcggta aaccacattg tcaagacgac gctctaaaag aagcatgaag
     5761 ttgaaaccaa gagttccttc tttgattttt gtagcttgta cgaataggtt acggaattgt
     5821 ttttccccca taccatatga aaagcgaagc ttttgcttct cagcaagttg caagccatat
     5881 tctgaaagct tgctacggtt gttagggcca tgctgaccag gtacgtagtt acgacgtgcc
     5941 aattccttac ctgtgcctgt caatgacaag ccaagacgac gtgattgttt ccatgatgga
     6001 ccagtataac gtgacatgta tcatgtcctc ctctaaaaaa tataacgagg aaataactgt
     6061 ttgaaaaatc ctgattcgtg caggaggttt tcgcctaaac agcaaaggtt actcaattta
     6121 gttaaccgcc tgttgacgag cttcatattt ttctgctgtt atttcacaca aaactaattg
     6181 taacatgaaa aaggtattga ttcaagtttt ttttacattt ttaatatcat atcatcaaaa
     6241 atggttagct gtaagctcaa agatgatgtt aatcatatgg caaacaagct tttacacaac
     6301 acttcccgag taaacaaggc tttttaatac cgataggaaa ttctttgaaa atagcatatt
     6361 atgttttgat atctaatacc gagagtctca gagtaactgc ttttcaagaa agctagtccc
     6421 tattattagt ccgggcttca ttcatttgct aataagttct tcaaggcttc aaattgattc
     6481 atatctttac acagctgtca acaaagtgta aagaaaaagc cctaaatggg cattgatttt
     6541 tcaatcaaaa taacgaatca gtgttttttc cgtcaaaata tctgaatagg tataagactc
     6601 aacataagaa ttattcgctt cccctgaagc atctgggttc ccctgatact caatgataaa
     6661 taaagaaggg taaacctcta tcaatctgcc aaccttattt ttttcacgct tacgaccatt
     6721 ttcaagtgtt aactcaacca actgaccttc atgagcctta atgtcttcct ttattttttt
     6781 cattttggca acatctgtaa atgcatcact cattctcttt ccctctttct tatctttcct
     6841 caaattgagc tattgtcgaa aatttattgt attccttttg aaacatcagc ttaactgtcc
     6901 cacgcgcacc tgccctattt ttctcaagaa tcacctcaat tgtattatcc tcaagagcct
     6961 cttctgtgct gtcgctttct ttacgataat aatcatctcg gtacaaaaat gcaacaatat
     7021 ccgcatcctg ctcgatagag ccagactcac gaatatcaga caaaactgga cgcttgtcct
     7081 gcctctgctc aacaccacga gaaagctgac tcaaagcaat aacaggcact tttaattcct
     7141 tagctaaaat ctttagctgc cttgaaatat cagaaacctc ttgctgacga ttttcaggtc
     7201 ttgtaccagt gatcagttgg aggtaatcaa tgacaattag ccctaagcct ccctcaacct
     7261 cctgagacaa tttacgtgcc cttgctctga tctcagtaat cttaatgcca ggtgtatcat
     7321 caatatagat aggtgcttct gccaaggctc cttgggcaat ggtcacatta ttccagtcct
     7381 gatcagtcaa ctgaccagtc ctcaagctat gtgaattgac cattccctca gcggccagca
     7441 tacgatcaac aaggctttca gctcccattt ctaaggagaa aatggcaact gctctctttt
     7501 gctttgtacc aacattttga gcaatgttta agacaaaggc tgtcttaccg actgcaggac
     7561 gagctgctaa aataatcagt tgatctgggt gtaaacctgt tgtaatcttg tcaagatccc
     7621 taaagcccgt tggtaaacct gtaacgtctg atgtctgctt agaacgaacc tcaagatttt
     7681 cataattaat ctttaaaacg tctgagatct tacgaaagcc actgcgattg ctatgctcac
     7741 tgatatcaac caaggccttc tcagcacttg caataatatc ctccgagtca gatgctcctt
     7801 cataggctaa gtttacagtc tctgtcaacc tattgatgat atcgcgtagc atagcctttt
     7861 cagctactat tttagcatag tattctgcat tggcactggt aggtacacta ttaaccagct
     7921 caacaatata agacaagcca ccaatatgtt gaaggtcccc ttgatcatca agaatcgtcc
     7981 ttaccgttgt tgcatcaata gcatcatttc gatcactaag ccttatcatt gccctgaaaa
     8041 tgaccttatg agaatactta taaaaatcct ctggaccgat aaattctcta acggtaatca
     8101 acttgtctgg ggaaataaag atagagccta gtacagactg ctctgccaat aaatcttggg
     8161 gttgaactcg taactcagca acttcaggca aactcagcac ctccaaatct tttttaggct
     8221 gatgtgctat gcctcagcaa tgtttagttt tatttcagct gtcacttctt tatgcagctt
     8281 aactggcact tcgataagac caatagcacg aatagggtga tctaaaacaa tatgacgctt
     8341 gtcaaccttg accttaaatt gcttttgcaa ttcctcggaa attttcttag ctgtaattga
     8401 gccaaaggta cgcccatctg gtccaacctt ttccttaaac tggacacgag ttttttcgtc
     8461 atctaagatt ttcttaacag ccttagcctc tgctaggatt tcagcctggg ctttttcctc
     8521 agctttttgc tgccctctta gctggccaat tgcttgactg ctagcttcct ttgctaaatt
     8581 tttcttaatc agaaaattct gagcataacc agtgggaacc tccttgattt ctcctttttt
     8641 tccttttcct ttaacgtcaa ctaaaaaaat gactttcatg actctacctc tcttgtttct
     8701 ttcattgtgt tatcaattgt ttctagtaac agctgcttag cctcgctaag actgatatgc
     8761 ttcatctgac acgctgctaa gttgaaatgt cctccgccgc caagcttttc catcattctt
     8821 tggacattga tcttactacg acttcttgct gatatagcaa tcttatcagc tcctgtctct
     8881 acaataacaa agctagcctc aatatgggcc attgatagta tggtatctgc tgccttacta
     8941 gcaatgacat tactataata ttgcccagca agcccagttg caacgataat ggagtcgcta
     9001 aggcgctcac ctctgagaat gatctcatta acctgcttat agtcatcaaa atcagttgct
     9061 gaaatatttt gaatttcgac gctatcacta cctctgcttc gtaaataact ggcaacatca
     9121 aaggttctac tggtgacacg tgttgaaaaa ttcttagtat ccagcataat accagccatc
     9181 aaaacacttg cttgaatctt gtttaagcgc ttcttcgcat tttgaaactg gattaattct
     9241 gtcactagct ctgcggcact gcttgcacca ctttcaataa aggtcaagat agcattatct
     9301 ggaaaatcat catctcttcg gtgatgatca acgacaataa catcttgaaa ttgctcgtaa
     9361 aattccttag acaaggttaa ggaaatctta gagtggtcca ccattactaa cagtgatcta
     9421 ggggtcgtaa gccccattgc ttgagaaata ctgataagac gtgtcttacc atcagcctgt
     9481 aagcgctcaa tagctctttc aatgtctgga ctcatctcat ccggattata gacagcaaag
     9541 ctgttttcaa taatgttact agcaaaaaat tgcatgccaa cagccgagcc taaggcgtcc
     9601 atgtccagtt tacggtgacc tacgataaac acattatcaa ccattttgat acggtctgaa
     9661 atagctgtca tcatggcacg cgtcctagtt ctagagcgtt taaccgtaga aacagagccg
     9721 ccaccaaaat agaccggatt tgtatggtct gcattttcac gaataacaat ctgatctccg
     9781 cctcggacaa gagcaatatt cagattctca agagcaacct gaccaatttg acaatgattt
     9841 tcctctccaa aggaaatgcc catacttagg gtcaatggta gctgcgcttc ttgggcttcc
     9901 tttcggaact gctctaaaat agaaaactta tcgtccatca gcccttttaa gatcttatag
     9961 tctgtaaaaa agtaaaaacg atccatatta acacgtcgat aaaatacctg cttagactcc
    10021 ataaactcag ctatgaaatt agccacaaat gaatttatct ttgacgtatc agcatcagat
    10081 aagtcatctg taatgtcgtc ataattatcc acagaaataa taccaataac tggctttagc
    10141 aagctagaat ctgctgattg tctactacca acagagctat caaaaaagta aaaaatacct
    10201 gatgccacat caatataaga cgtgtatcga ttgccagaaa cctcaaaggt ttgagaaata
    10261 tcacttttac gcttatcagt gagaagctgt tggatcatct gttcctgtaa aaaaccggcc
    10321 tcatcagtga aaatcagctc tgcgtaagga ttgtaccatt caatagcatt ggtttcttga
    10381 tcaaactgaa taacaccaac tggcatgtta tccagtaatg tttttaaatt attttctgtt
    10441 tgttcgttca atagctcaat gtggtctaaa tcagacaatt cgtaaacctt tttttgatac
    10501 caaagcaagg ccgcaacaaa caacaacact aaaaaaatag ctagtgtaat cagcattttt
    10561 gattgcatga ttctaacaca taaggctagt aagccgaata aaatcaactc catcataatt
    10621 aaatgaatgg tttcaaaacg aaatcttttc atctttaacc tcttaatccc gtattatacc
    10681 ataaaacagc cctgaaatac agagctgtca gtggttttga gattacaatt tgatgactat
    10741 tatgttttac ggcgagcctt tccattacct tcaaggtaaa ccattaaaat gctaatatct
    10801 gccggattta cacctgaaat gcgactagcc tgaccaatgg tttctggatt gattttctta
    10861 aatttttgcc ttgcctcagt agcaattgag tcaatagcgt cccaatcaat ggtcttagga
    10921 atccgctttt cctccatacg cttcatttta gcaacctgat caagggcctt tttgatatag
    10981 ccttcgtatt tgatctcagt ttctagtagc tcaatcagct tagcatctaa tccctcagca
    11041 gcaggaccta taaatgacac tacagtggca tagtcaacct ctggtcgacg cataaattcc
    11101 ttagctgtca ttgcgtccgt caaggactta aagccaagct tttgaacacg agcattggtt
    11161 tctttgattg gctttaattt gatactatct agcctcttta attcattgtc aaattgattt
    11221 ttcttgattt caaaggcaga ccaacgctca tcgtcaacca agccaatctg acgaccaatt
    11281 tcagtcaatc gcatgtccgc attatcatga cgaaggataa gacgatattc tgcgcgtgat
    11341 gtcagcaaac ggtaaggctc caaggttcct ttggttacca aatcatcaat cattacacca
    11401 atataagcgt cgctgcgctt taaaatgagc tcaggcttac cctgaacctt caaagcagca
    11461 ttgataccag cgacaaggcc ttgaccagca gcttcctcat agcctgaggt tccattggtt
    11521 tgcccagctg taaaaagccc tgaaatcatc tttgtttcaa gggtagcacg aagctgatga
    11581 ggtaatacaa tgtcatactc aatagcatag cctgttctca tcatctcagc attttcaagc
    11641 cccttaatag agtgaaccaa ttccttttgg acgtcctcag gaagacttgt ggatagacct
    11701 tgaacataga cctcctcagt gtcaaagcct tctggttcta aaaagagctg atgacgctct
    11761 ttatcagcaa atcgtacaat cttatcctca attgatggac aatagcgtgg gcccactccc
    11821 ttgacgactc ctgaaaacat aggtgctcga tataggtttt tagtgatgat atcatgacta
    11881 atctgattag tgtaggtcag ccagcaagga atctgattag ccaaataatc tttgtcctta
    11941 gacataaagg aaaaatgatt tggagtcaca tcaccaggct gaatctctgt cacctcataa
    12001 tcaatagaag aagccttgac acgtggtggg gttcctgtct taaagcggcc aatttcaaga
    12061 ccaagctttt tcaaattatc agctagtgtc actgaggcca agctgttatt cgggccagac
    12121 gaatatttca attctccaag gataatctca ccacgaagag ctgtacctgt tgttatgatc
    12181 actgcctgag ctgcatattt ttgccctgtt gctgtcagca ctccaacaac cctaccattt
    12241 tctactaaaa tatcatcaat catagactgg cgaagagtga ggttttcttg cttttcaaca
    12301 gtatgcttca tctcacgtgc atacaagctt ttatctgctt gagctcgtaa tgctcgaact
    12361 gccggtccct tacctgtatt gagcattttc atttggatat aggttttgtc aatgtttttc
    12421 cccatctctc caccaagagc atcaatttcg cgaacaacaa tacccttagc tgaccctcca
    12481 atagagggat tgcatggcat aaaagccagc atatcaagat ttatcgttgc taataaggtt
    12541 ttacacccca tacggctagc cgctaagctg gcttcaacac ctgcatgtcc tgctcctaca
    12601 acgatgacat cgtaggattc tgtaaattca tgtaccatat ctactccttt atctcaatat
    12661 gttttatatg ctgaggctgc ctgtcccaat gctttatagc cctttttaaa caactaggat
    12721 tgagccttat cttatctaga tcatcaagag caacccactc acaaacccta gtacaatcac
    12781 cctcaactac agaagggcta gaatcagata atagactcac aatataatga aactcaatct
    12841 gatgaaagtt cactccttct agacaaaatt gattttcaac cacaaaggct aactgagcaa
    12901 ctgaaacctc agctcctacc tcctctagaa cctcacgctt gacagcttct tctgtgcttt
    12961 ctccaacatg aatagcacca cctaaaagat aatagtcctc tttgggtgat ttggcaagat
    13021 aaatatagcc atccttaatt attaacgctg aagccctaac accaaagcta tggtctgcta
    13081 tccttgttct aaaatcctga accatctttt ctccttgaca ctgtttttaa gctataaaaa
    13141 tagtcaaaac ctgagaaagc tgtaagccaa aaagacttac aattcccatg agctttgacc
    13201 atcatcgtta ttgttaacct tattctatca aaatctgcca gcttgtcaag acttatcaga
    13261 tgacaaaacc gtcaacttta ttgacacatc tgtcaattaa catgtcaagc taaatatatt
    13321 gacaaggctc gccatcttta tacgccatat caataatacc accaccaaga cactcatgac
    13381 catcataaaa aacgactgct tgaccaggtg taatcgcacg ctgaggctca gcaaaaacaa
    13441 ccttagcttt gtctttcttg acatgaaccg tcaccttaga atctggctga cgatagcgga
    13501 actttgctgt gcattctaag gtgaattctt caggaacttc tcttgtaaac tgaatgacag
    13561 aagcgtcaag actagttgac attaaggact cgtggtaaaa gccttgacca acataaagga
    13621 tattttgtga aaggtctttt ccaacaacaa accaaggctt gttatctcca ccctgctgac
    13681 caccaatgcc aagtccccca cgttggccaa tagtataata catcaagcct gcatgctctc
    13741 ccatatcacg accatcaaca gtcatcatac gccccttttg agctggtaaa taatggctaa
    13801 gaaaggtctt aaaattcttc tcactaataa aacaaatccc tgttgagtct tttttctttg
    13861 ctgttgcaag gcctgcttgt tcagcaatag cacgtacctc tgatttttgc aggtgcccca
    13921 agggaaacat ggttttttgg agttgctctt gtgatagttg gcttaaaaaa taggtttgat
    13981 ccttaccctt atcaagacca cgcagcatat ggactacacc attctcatca cgtttgattt
    14041 gggcatagtg acctgttgcc acataatcag cacccaatgt catcgcataa tcaagaaagg
    14101 ctttaaactt tatctcctta ttgcacatga catcaggatt tggggtgcgt cctgaacggt
    14161 attctgctag gaaatactca aacactctat cccaatactc tttttcaaaa ttaacagaat
    14221 agtaaggaat accaatctga tcggctacgg ctgccacatc tttataatcc tcagtcgccg
    14281 tacaaacacc aaattcatct gtatcgtccc aattcttcat aaagacgcca atcacatcat
    14341 atccctgctc ctttaacagc aaggcagtta cagatgaatc aacaccgcca ctcatgccaa
    14401 caacaacacg tgttttcgag ttatctgtca tcatttattc tcccatcaat ataagataca
    14461 aggacatgag aaaaagaata gaacgaatca acttgcctaa acaagactct agcaaatggt
    14521 tcatttctat attttttgtc tttgtccaag tgttttctca aagctcgatt tgaaggtcga
    14581 tttgaagcgc cgctagacgc atgactatta taacagtatt gtctcttatt tccaacaata
    14641 tcttttttca taacaaacga catttgatta gcgatttgtt ataataaaaa ggataaaaag
    14701 agcatggagc atatatgaac acacaaaaat ttcaatcagt ttttgacatc attggaccag
    14761 tgatgattgg accatcgagc agtcataccg ctggtgctgt tagaatcgga aaggttgtcc
    14821 actccatttt tggagaaatt cctgatgagg tgacctttca tctatacaat tcatttgcta
    14881 agacctatca aggccatggt accgacaagg cactagtagc tggtattatg ggcatggata
    14941 cggataatcc aaacatcaag aattctcttg aaattgctca tcaaaagggc attaaaattt
    15001 attgggatat tttaaaggat agcaatgctc cccaccccaa tactgtaaag attagtgtca
    15061 aaaaggctga taaagcaatg agcattacag gtgtgtcaat tggaggagga aacattcagg
    15121 tcacagagct aaatggtttt tctgtttcct tgtctatgaa tactccaacc ttgattattg
    15181 tccatcaaga tatccccgga atgattgcta aggttacaga tatattgtca gctagtgata
    15241 ttaatatcgc tcaaatgact gtgactcgtg aaagtgcagg tgagaaagcc attatgatta
    15301 ttgaggttga ttctcgtgat tgtcaagttg ctgtcaagca gattgcaact attcctaatc
    15361 tgcataatgt caatttcttt gactagaaag gtatattatg ttttacacaa ttgaagagct
    15421 tgtcaagcag gctgatgata ggtttgatgg taatgtagca gagctgatga ttgctacaga
    15481 ggttgaaatg actggtcgaa gcagggcaga aatcctatcc atcatgtcac agcatttaca
    15541 ggtaatgaag gattctgttg tcagcggatt gacagcaacc aaatctatta gcggattgac
    15601 tggcggtgat gctcttaaga tggatcatta catcaaaaaa ggaaaggggc tttcagatca
    15661 aaccatttta acagctgtga gaaatgctat ggctgtcaat gagctaaatg caaaaatggg
    15721 acttgtttgt gcaaccccga ctgctggaag tgcaggctgt ctacctgctg tccttgctgt
    15781 tgctattgat aagctcaagc tatcagaaaa ggaacagctg gactttctct ttacagcagg
    15841 tgcctttggc ttagtcattg gaaataatgc ctctatctcc ggagcagaag gaggctgtca
    15901 agccgaggtg ggctctgcct ctgcaatgag tgctgcagcc cttgttaagg cagcaggtgg
    15961 taccgcttat caggctagcc aagcggtagc ctttgtgatc aaaaatctat tgggattggt
    16021 ttgtgatcct gttgctggct tagtcgaagt tccctgtgtt aagcgtaatg cattaggatc
    16081 aagctttgct cttgttgctg ctgatatggc attagcgaat attcagtcac aaattcctgt
    16141 agatgaggtt gttgatgcta tgtatcaggt tggtgccgca atgccaacag cctttaagga
    16201 gacagctgag ggaggattag cagcaacccc aacaggtaga cggtatagta aagaaatttt
    16261 cggagactaa tataatcaag taacgataga ctgaggagac gtcatgaaag caatcctatt
    16321 tgacttagat ggtactttgg tggattctag tataggaata ctaaatgcct ttgaatacac
    16381 ctttcaaaaa atgaaaatcc cttgtcctga tcatagcata ttatcgtctt acatcggacc
    16441 acccttagaa gcgacctttt cagcattttt taggaatcag catgatgtcg aggttgctat
    16501 aacacacttt agagattttt acagggaatt aggcatttac caagcaaggc tttattctgg
    16561 aatcacagag ctattagata atctctcgca agaaggtctt gacctctatg tgacaactag
    16621 taaatatgaa cctatggcaa ggcaaatgct tcaggattta acgattagcc attatttcaa
    16681 agctatccta ggctctattt ctaatcggtg tcacaagttg gatatcgtca aggcatgctt
    16741 acaagatttt gctattaata aaaaagaagc tataattgtt ggagatacca aatttgacat
    16801 gattggtggt aaacaagcag gcattacaag acttggagtt acttggggat ttggttgtca
    16861 agaggattta caagcacatg gcgcacaata cattggacac acaccccaag aggtgattga
    16921 gattatccag tcattgtaaa acgatactaa aaacctatca tcacacaaga tgataggttt
    16981 ttaacgctgt tatctgttct tagtagcccc aagctgataa gccctgtgca cgataggcat
    17041 ttaaggctga atttacctga tcctgaacgg ttgcagttga tccccagcct ggcatggttt
    17101 ggaataatcc tgaagcacct gaaggattag ctgcgttagg gtttccattt gactcacgag
    17161 cgataatggc ttcccaagta gcttgtggaa caccagtagc tgccgccatt tgagctgctg
    17221 cttcactacc gatagcccct gcggtattgc cgttagaaag gattactcca ttgctataag
    17281 ccactggtgt agctgcatac tgagcttgag gagcagcctc ttgcacagca ggactagcta
    17341 cctcagaagc tactgattcc tgagctggtg ctgcatcagc agaggaaggc tctgcctgct
    17401 cagctggctg ctccttggtt gcagcctttg ctactgttga tttttttgtt ttatgatgtt
    17461 tcttcacaac cttagtatca gaagctttag cataggaatc agtgtttaca ttttcacttg
    17521 aaaaagcaaa aactactgcg agcaaagcaa tagcagctgc tacaatgcca aaactaaaat
    17581 aacgttgttt caaaatgtct tgtttaaaca ttaaataaat acctcacttt tctctgttat
    17641 ccatattaac tgttaattat tacttgtcta tttaagatat attaaaaata ttacagcaat
    17701 attgatattc caagttttct agcctgatat cagtgttttt tgagcttaag aagctcaaaa
    17761 taaaaacaat gcctaagttc agacctgtgt aacagatgat ttaagcattg ttattattaa
    17821 taaattctag ttgctacagc ctaacaaagg ggctgctgta atatagctag gtgagccttg
    17881 agggactttt tagacagaaa aggaaaatcc ccaaaatgac taccaaaata atggctagag
    17941 tgtcttttaa ttgccagctt agcaggcggt attttgttcg actgtcaccg ccttgatagc
    18001 ctctagcctc catagcgatc gctaaagcgt cagctctttt aaagcttgaa gcaaaaagag
    18061 gaatcaaaat agggataatc gactttacct tttgaataag attgccttct ccaaaatcaa
    18121 cacctcgcgc tttttgcgca ttcataatac gagttgtatc gtccatcaag gttggaacaa
    18181 accgtaagct caaagataac atcaaaccga tctcatgggc aggtacctta aacctaacta
    18241 aaggcttcaa cagcgcttca acagcatcag ataagcttag tggggtggtg gttagggtta
    18301 acagcgtgga aaagaaaata atcaaaacaa atcgcatgaa aatcaaaatg gcttgactta
    18361 atcccaagct tgttatctta attattccaa gctgaaaaag aactgatcct ccctgtgtaa
    18421 aaaaaacttg aaaaagcgtt gtaaatagga taataccaat cataggctta acaccattga
    18481 aaaagaaaga ccattttatc tgtgacaaga aaatcagcag caaggtaaat gctaacagca
    18541 aaagattagt taccacatta ttggcccaaa aaataatgat aatatagata atcatagcaa
    18601 gcagcttgct tcttggatca agccgatgaa taattgaatt cccaggaata tagcgaccaa
    18661 gaatgagttt atccatgctt taatacctct cttaattcct ccaaagtaat gggtaaatag
    18721 ggtaaatcaa agccttgctt agccaggcgt tgggcaaagg ctgtcacctt agggacacct
    18781 aattgttttt cttttagcaa atcaatgtgt tgaaaaatag cctttggctg acctgataag
    18841 atgattttac cagcttcaag gacataaaca aaatcagcat aattagcaac atcgtccatc
    18901 agatgtgtca ccagtacaat ggtcatgcct gattgatgga gcgatttaaa aagactcatt
    18961 aattcctttc gccctttggg atcaagccca gcagtaggct catctaacac caaaatatcc
    19021 ggctgcatcg caagaatacc cgcaatagca accctgcgca tctgcccacc agaaagctca
    19081 aatggatttt taccaaatag ttcctctgaa atccctacta gggttaattt ttcacgcgct
    19141 aaagcttccg cctctttctg agaaacacca aaattttgtg gtccaaaggc aacatccttc
    19201 aaaaccgttt cctcaaaaag ctggctctca ggaaattgaa agactagacc aacctgctta
    19261 cgaataggct taatatcttt attttttgac tgactagtta tctccttgcc tgctaccgta
    19321 accttgccgg tggtcggcag atgcaagcca tttaagagct gcataatcgt tgacttgcct
    19381 gagccagtat gaccaataaa agccgtataa gagccgtcta caatatcaag attaacgtca
    19441 aaaagggcac gcccctcaaa gggtgtccct gcttgatacg tgtagcttac attttggaaa
    19501 tgaattgaca tagctgttcc tctaattcct tttctgtgag atagattccc tgtatagggt
    19561 agccgtcttt ttttagcata ttaacaacag aggttgtaaa aggaatatct aaacctagat
    19621 tgatcaattg attgccccta gcaaatagct cctgtggagt cgagacagac tcaacacgcc
    19681 cattgttcat caccaaagct cgatcactaa gagccacctc atcaagatca tgtgtaatag
    19741 atataacagt tagttggtat tcttgtctaa tagattgaat tgtccgaatc aactccagac
    19801 gcccctttgg atccagcata ctggttgctt catctaaaat gatgatcatt ggccgcatgg
    19861 caacagcacc tgcaatagca acccgctgct tttgaccacc tgataatctg gaaggctcct
    19921 tatccttaaa agcctccata ccgaccagct gcaacgcctg atgaacacgc tctatcatct
    19981 cctgatggga aacacctttg ttttcaagac caaaagcaac gtcatcttcg acagttgcac
    20041 caacaaattg gttatcagga ttttgaaata ccatgccaat tttatgacga atgtcccaga
    20101 cattgtcctc tgtaagaaga tcaccatcaa caaaaatctg gccggcttct gctttcaata
    20161 gcccatcaat taacctaaca acggttgact tgcctgagcc attatgccca atgatagaca
    20221 accactcgcc ttgtttcaca tgaaacgtca catcatctag ggtatatcgc tcctggtcct
    20281 gcttatactt aaatgtaaga ttcttaactt caataatatt tgacattgtt atttaaaggt
    20341 atccttaaaa agaaagcttg ctcctttgaa ataatcgtaa cctgaataaa tcgtaaacaa
    20401 tagagcaata tacagcaaaa cagtgcctaa aacagtccaa tgacacagta aaaagatgat
    20461 ggaaagcatc tgtgctactg ttttgatctt accaggcata gcagctgcta ggaccttatc
    20521 tccagtctca accaatagca aacgaagtcc tgtaacagct agctcacgac agataataac
    20581 cgctgacacc caagccggta ccagctctaa gcccactaac ataataaaag cactcatgac
    20641 aagcatcttg tctgccaatg gatcagcaaa tttaccaaaa ttagtaacaa cctgccactt
    20701 acgtgcaagg taaccatcta aataatcggt caggcttgcc actgcaaaaa taatcgctgc
    20761 aaaggtatgc caaccgactg tctttgaaaa agaggtgatc aacaaaaaca atggaatcat
    20821 gacgatacgg gcgagagtta acaaattggg aatattttct tttttgatca tgcttatacc
    20881 ttattattgt atcttcagtg tgatatagct gatatcagta cttgtcattg ctgataaatc
    20941 taggggctga ccatcaattg ctactgaaac accctttgtt acgcctagtg tcaacaagga
    21001 ttctgttgtc tcagcaggca aggtagtaga ataagtcgga ttgtcctttg ttagggtcat
    21061 accagcctca ccaatttccg aattagtgag ggaaatccaa ctgctctcag catcagtcag
    21121 tgacactgta acatcaacag cttcttttga tttagtaata ttagcaatca agtaattctc
    21181 tgcgccctct gttgtgatca ccgtcttagg ctcagatgag ctggacgctg ttgagtgact
    21241 gctttgtgat gacttaagaa aagacatctc agcctctttt gctttttgac ctttatcaaa
    21301 ttgcttccaa acagcaaaac caataacacc aacaatagcc acagcaataa gacctagtaa
    21361 ggctgatgga aaggctgatt ttttcgtttt agcactattt ccataacgac ttagccttga
    21421 agcactggtc tctctagtcc gtctatggtc agtagcctta aagtgactag ctgtaggagc
    21481 tgatttgctt gaggatagtg acgtcttgac aggaatcact agggtttctg gttgagtcct
    21541 tgaaggctct ggttgagcta ttttttcaga atagctattc tcttgtagcc tttttttgct
    21601 gagcttttct tcaacgattt gtgtgactga tggtgtacct gtttcctttt taaagctcac
    21661 ctgcagctga tacaagcgtt ttaagctatc aaagtctaag ccaacaatat cagcatattg
    21721 ctttagaaaa tgaccaaact tttcttctgg aatgattttg aactggtcaa gctccattgc
    21781 caatagataa tgcgaggaaa tgccagtttt agcttcaatt tcgtctaatg ttatgttttt
    21841 tccgacacgt gtttctctta ataattcacc gagacttgtt tctctcatac gagtacctca
    21901 aaaatattgt aataagacca ttataacaga ttttaagcta tttgggaaag actgtaaaat
    21961 ctgaagtagc tgcatgctca aaaaacaagc ttcctatttc gataatatcc tttaaagcta
    22021 gggtctcaat aatcctagga atatcaaaat aggtctcttg ctctgataaa tgaaggctaa
    22081 attggcttgc cagctgatca atagcgtcta agctttgcat aaaatcccca tacatttcct
    22141 ttttcactag ctctaagtgc tcctcattaa cgtctcttga gcatctaaaa tcggaaatct
    22201 tttttctaat gctgttagac attgcaatag gctgactagt atctgaagaa atcaatacaa
    22261 attggaaatc cctttgaatg tcaacctcta tatcaaagga gtcgtctatc ttgccctttt
    22321 cataccaatc ctgataggtt tttgacgtcc agccaaggag caccgctagg agcagtctaa
    22381 gagctacctg ataggtgagt agagaatact cgcttgacat tagctgaccg cgaaagccga
    22441 ctgctaattt ggcagtcgca acgtccatat caatagatct agacttgatc acagggtagt
    22501 aggtcaatgg agctatctgt acatcatact gcgtctgact tggttgacta tcttgaaagg
    22561 cttcaatagc tgtaaaggct tcttcaatgt caatatcgcc aataatcgtt aagaccatgt
    22621 tagaagggtg ataaaaataa gcatggctgt cagccaataa agagcctgta atgtccctga
    22681 tagactcctt ggtcccagca atatcaacag ctaagctggt attgggaaag aggttctgta
    22741 agataccact gtaagcctga taatcaggat cgtcctgata catctcaatt tcttgagtga
    22801 taatatgttt ttcacgatta accgactcct ctgtaaagct aggagctgct acaaattcct
    22861 gcaaaagtct cagactttct tgccattcat tgacagttga aaagaaatag ctcgttttat
    22921 caaaggttgt aaaggcattt gtttctgatc ctaactgtgt aaatgtaaga gcaatatcat
    22981 taccatcttt atcctcaaat agcttgtgct ctaagaaatg agcaacacct gacggcaagt
    23041 caaacctttg acaattgact gtaaagcttg tgtcaagaga accaaaacga gcagtcagca
    23101 tagctgtttt ctcagaatag ccctctttct ttatcaaata aacccttaaa ccatttgcca
    23161 attgaccgta gtgtaaggtc tctttaatgc tgggatagtc ttttttcagt agtgacgtca
    23221 tcttattttc cctctaaaaa atatacagct tgcagcttga gtagattagc tgtcctgaca
    23281 atatctagct tgctaacctt gtcaatctcg tcaagccaac ttgacaaagt ataggaagga
    23341 tctatataag atctcatgta ttccagctca atcaaggctt tactattatc ctcagatagc
    23401 aaggcgttat tttttagcat tagctttgtt ttcttgacaa ggctgcttga aaagcgcccc
    23461 atcttgatgt cattgagctc tttaaccatt agctgcaggg ctcttgtccg gtgctgtcta
    23521 tctatgccag cataagcctc aaataagcct gtgtaaacat caaatcgact accaatacta
    23581 taggccagcc cctccttctc acgaatttgg gtaaagaagc gagagtgtgt aaaggctcct
    23641 aatagaccat ttaacacaac taaggcataa tactctgctt gcccataaac cagcggaaaa
    23701 tgataggcta gctctaaaac agactgatta agctgctttt gctcgaccaa ttcgttgaca
    23761 acattgacag gctgctgtaa ataaaagaaa tctagctttt tcctgcgtcc ctcaaaggga
    23821 aattggtgta acaattgtac catacgataa tcatcaaaat caccaagaat aaaaatatca
    23881 atctgatcct cattcaacat tttatgaaat tcttgatagc ttgtgtaggc tgtttcttta
    23941 gcaattaact cagtattacc atattttgac agcttcaggc tatcattagc ataaaataat
    24001 tgcttggctt ttagggcact ataataaaag gaatcctcct tatctgcctc gacataggtc
    24061 atcaaatgtc ttttttcgat gtcaaatagt ttgggctggt actgagccac tgataacaaa
    24121 ggagaaaaaa ggatatcctt tagaaattga atcatttcgt ctagaagctt ctctccataa
    24181 aaagcatact gatcctgaat aaaggtaatg tcaatatcca caatatgaac caaacccttg
    24241 gttgacacat gagttgacag gcttgctcca tacatttgtg ctaatttttc tctaaattgc
    24301 ttggcagtag gataggtatc gttagccgtt gctaacattt gagctactaa gactcgcttt
    24361 gctaccgttt tttgattcaa atcacctgaa aagcgaaacg ttatctgatt cgttttaaat
    24421 gttttgtttt ttatcagatg aagctgaact ccctgaataa gtttcataat atttccttat
    24481 taataaatgt gtgatctcta gaattatacc atttttatcg ctattcgttg agtgttaaca
    24541 tcagtctggt agcctatttt gactctttat caaaatgcta tcctgtggct atagtctaga
    24601 ctttagaagg tcagcatttc agcattatta tttagtggct ttttatgcta taatgacttg
    24661 aatgacaaat tggagatgac tatgacatac acactattta ctgactttat taccctacaa
    24721 gctttattaa aggagcaagg tattatccaa agtggtggtg ccattaaagg ttttttagct
    24781 caaacagagg tttttttaaa tggtcaagag gaacaacgac gtggcaagaa gctaagagtc
    24841 ggtgacgtca tcaccattcc atcacagcac atcaagattg agcttgtagc gcctagtcag
    24901 gccgaaaaaa cagcctatga agctgaaaag gcagaaaaag agcgagttgc taagatggtt
    24961 aaacaaatga atcaacaggc taaaaaagca cagaccaagc aagcagctac taccaaaagc
    25021 aagcgtggtc aagctacctc agctgtaaaa gctaagtcta atcaccaaaa gcctattcgc
    25081 ttcccaggat tgtagcatgt ggatcaaaga actaaacctc acccattacc gtaattatca
    25141 acaagcctca gcagcctttt caccgggctt gaatgttttc attggtgaca atgcgcaggg
    25201 caagacaaat tttcttgaag ctatttattt tttgtcagta acaagaagtc atcgcaccaa
    25261 atctgataag gacttaatct actttgacga aagggattgc tctatatctg gaactcttga
    25321 gcgccttagt ggtcgtgttc agctagaaat actgctgtct gataagggac ggatcaccaa
    25381 gattaacacc ctaaagcaag caaagctttc tgattatatc ggagcaatga tggtggtcct
    25441 ctttgctcct gaggatctac agctggtcaa aggctctcct aatcttagac gaaaatttat
    25501 ggacattgac ttaggtcaga taaagcctgt ttacttatca gatttgtcac attacaatca
    25561 tgtcctaaag cagcgaaatg cctatctcaa aagtgttcat cagcttgata atgacttttt
    25621 atctgtgtta gatgagcagc tggttaccta cgggagtcgt gtaatggcgc atcggttggc
    25681 gtttgttcaa tcactagcaa aagaggcaaa caagcatcat caagctatct ctaatggcct
    25741 agagaagctt tcgatctcct atcaagcctc tgtgagcttt gagcaccagc aagagattta
    25801 tcagcaattc atgaaccagc tcaaaaccac tcatcaaaga gatttcttga gaaaaaatac
    25861 tggtgttggc ccccaccgcg atgatctggt tttttatatt aatgacatga acgctaattt
    25921 tgctagtcaa ggccagcatc gtagcctgat tttatcactg aaaatggcag aggttagtct
    25981 gatgaagcaa ttaacaggtg acaaccctat tcttctactt gatgatgtta tgagtgagtt
    26041 agacaatacc agacaaacaa agcttctggg agctgtcaag aaagaaaatg ttcaaacctt
    26101 tatcacaaca actagcttag agcatttgtc tcagctacct aaggacatta gtctctttaa
    26161 ggttaataaa ggaacaatag aacgagattc tatcatgatt gattaactga gcaaactaaa
    26221 aaaagggcac cttaatagtg acccttttta cggttaaatt agttgatact ctatgatttg
    26281 acgataccta agaggatagc gccaacaata aagcaaagga tacctgtaat gacccagcgc
    26341 atctcttttt tggtttttgt ctcacctaag aataaaatac ctccgacaat agagataata
    26401 gcgcccaatt gtgaaaagct aaaagcaatc gccagaccag cctttgaggc tgctagcagc
    26461 atgaagatat ttccaactcc ccaaagcaag ccaacaacac tatttttgat aacatactgg
    26521 tcaaacgata ccttaaacga cataaacatg gctgcaccaa gcaccattcc cactgccatc
    26581 ggtaaaataa ccgacaacac atcaaatttc ataatgttat tgaacagcac agcatacatc
    26641 acatagccgg ttgtcgagta ggttaaggct ctaaagccct ttgaaaaatc atgcaattga
    26701 ttacttgctg cattcgtctc gtcctgcttg cttgaaaaat aaaaaccaac aatcaaaaga
    26761 agtaaggcaa tcgtaccaac gacaaattga ataggcttgg tccactcatg aaagaccagc
    26821 acaccaatca ggctacctaa aactagctga gaaccactag acaagggatt tgctactgaa
    26881 acacccatat actgcatggc atgaaattgc ccagtctgac caacagacca gataatacca
    26941 cctaaaatcc caaaaatcca gagcttcata gacatctcag gtctgactac taaccaaaca
    27001 actagagcaa atagtaaagc tcctatggtc attccaaagg tctgctgtga gggtttaccg
    27061 ccaattttat tactaacaaa gccaatactt ccccatgcaa acattgggac aagtgcaaat
    27121 aaaatacctt ccaaatttac atctccttta caataagttg acacatgatg ttaacgataa
    27181 aagtgctttc atacggagaa ttattatagc ctatttcctt agaaaataca ataacatgat
    27241 gtaaaaaatc atctgctcac acgcttctcc ctaaaaaggt gtcaaagtag ctgacagagc
    27301 ttatttactg caatgctaga ggattattta atgaaaaccg tttgacctta tggctggctc
    27361 tagctggagc tttgttaggg acttttgtga cctgagttcc aaagcaatca gcaactagct
    27421 gactgaaata gcctaagcgt ttgaggagta gagcaagatg attaaccata gcactagctg
    27481 cttgaccgga catgcttgct tctatggtag ctttgacaaa ggatagctca acgatgattt
    27541 tatccagcag tctgccaacc atcttttgac tagtgatgat gtcatctaaa tcaagagcgc
    27601 tgtaaactcc tttttcgatc aatcgactga gatctccatg caagttttga agccgatgcc
    27661 ttgcggtatt gactcgctgt atcgtatcag tcaatgccgg tactagagga catacctcag
    27721 ctctggcaga agcaataccg gatcttatgc ggcaaggata taaagcaccc agatttcccc
    27781 aatagctcct tgtcgttgta gaggtttcat ctttgatttc tgttcgttca acataaaccc
    27841 tatctgaaaa acgtctctct aatactgtca cgatattctt aaagatattc acctcagtag
    27901 tccaataatc aagtgtatca aatagccttg aaaaggttga cgcataaaca gaggcaacct
    27961 ttctggaata gtcccgactc ttttgttcca cctgctcatc aaaggcttgg agaatatctc
    28021 tgacatcatc taaaagacct gttctttcta ggtaagcatc atagctgctt gggacacaga
    28081 cgacatcagc acttccttga aattgaccat tttttaggct gttgcctagc cagttatctg
    28141 tagctgtgac attttgtgat acccctagga tcagctcact ggtattgatt atcatttttt
    28201 ccagctctat gatatcctgt aattccacgc taaatacctc ttttaaggaa tcgctaatac
    28261 cgtcaacttt actttcacgt aaacccgttc cttcaaaggt cttatcactc tccttcaata
    28321 gctgacgact ggcctcatca ataatctgcc aagatttcaa aagtgtcgag cgaccgataa
    28381 tactatcaat ccagcctgac ttttcatgct gagcagatga ggcaagctga agcgattttg
    28441 tgtttaagct cgctaattct gaatcataca tggccagatt gaggcgatta ttattcacat
    28501 atgggatctc atcataggaa aagggatagt ctaggctagc cgaatgagac agcatatcaa
    28561 acaagtcctg ctgaccaact aatctctcca aagaactttg caggctatta aaagtatcgg
    28621 ttaggccatt tgtagcaagc agggctttga tgttttctga aactcgcttt ttcctctctt
    28681 caaaggagtc ttttatggca tcattttttg cctgacattt ttcagtaatg tggcgaatcg
    28741 tttgcaggtc gcctgatata gaggattgaa ggttttgtgc aaggttagtc aggacaccag
    28801 cattgatgac aatcgtttgc ttatcagaaa gcacaccgta ccgagccgat gttgacgaat
    28861 caaagtaatt tctaaagcct aagtacagct cctctacctt agtgtctaat cggttatcgc
    28921 tgtcaatatc aataggcaac aggacattag catgaacaaa ccggccattt acgtctgtca
    28981 tgttgccata ttgatcatac tgatagccat gccacatatg ctgtaagact atatcattga
    29041 ccttttttgt attgacaaca aagacctgac cgactgctcc ctccttttgg tcaaagccca
    29101 taccaatgat gtcatgcgga tccacatagt tgtaaatgcg gtcatgcaag agctttgcac
    29161 gttttctttg atactcatta agcacacgat aggtgttggg gccattgtag atatagactc
    29221 cagagatacg agataagttt ttatcactaa cagaggtaac accgtactga actgtcatgg
    29281 agcctagcga atgaccataa aactcaaatg ttgcgttagg gtattgcttt aatgtcttat
    29341 tggtaaaggt tgctgccttt cggagctgag ctgtcccttt agttggtgtc tggtccggta
    29401 aaagaatgcg catagccata ggcaaatcat tgcctaccca atctgcaacc acatctactg
    29461 ggtgtttctg ccactggtct gggccagtag agccccggta cagcatggtg acatgcttga
    29521 cctgagcata gtctgccttg gtaggatgag ggggaagctt gacatctgtc acgacatagg
    29581 cttgaaaacc tgatatcgaa tcctctatct gagacacata accgatggaa aactcagaat
    29641 tatcatcatc aattaaaact ggtgaaccta ctgtatgttt ttcatactct tcctcagcaa
    29701 tccgttgtct ctgttcgtct gtcaggatca tcattttcac tctcctttta gtagtttttc
    29761 taacttttct gagcgataat tactagcgat ctctaaattt ctttctaaat catatctact
    29821 aaggcgaacc cttaaataag tatctggatc atcattgata atcaggtgaa tagaaaaacc
    29881 tcccctggct tgaatgaact gtgaactgcc ccccaaaagt tagacataaa atctaacaat
    29941 tggggggcta tttttatgac attgagttat gaagacaagg ttcaaatcta tgagctacgg
    30001 cacattggaa agtccattaa atgcttatca gaaaagttta gtattg
//
LOCUS       DARYXZ010000028        29140 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYXZ010000028 DARYXZ010000000
VERSION     DARYXZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29140
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..397
                     /locus_tag="TV186_001120"
     CDS             <1..397
                     /locus_tag="TV186_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1532519.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            441..1106
                     /locus_tag="TV186_001121"
     CDS             441..1106
                     /locus_tag="TV186_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1532520.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDCIHTVRGVGY
                     IIK"
     gene            1103..2080
                     /locus_tag="TV186_001122"
     CDS             1103..2080
                     /locus_tag="TV186_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1532521.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TV186_001123"
     CDS             complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TV186_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL1532522.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
     gene            complement(3407..3844)
                     /locus_tag="TV186_001124"
     CDS             complement(3407..3844)
                     /locus_tag="TV186_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL1532523.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
     gene            4045..4737
                     /locus_tag="TV186_001125"
     CDS             4045..4737
                     /locus_tag="TV186_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1532524.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(5113..5589)
                     /locus_tag="TV186_001126"
                     /pseudo
     CDS             complement(5113..5589)
                     /locus_tag="TV186_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TV186_001127"
     CDS             complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TV186_001127"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL1532525.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7651..8349
                     /locus_tag="TV186_001128"
     CDS             7651..8349
                     /locus_tag="TV186_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1532526.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            8561..8893
                     /locus_tag="TV186_001129"
     CDS             8561..8893
                     /locus_tag="TV186_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL1532527.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            8908..10479
                     /gene="ffh"
                     /locus_tag="TV186_001130"
     CDS             8908..10479
                     /gene="ffh"
                     /locus_tag="TV186_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL1532528.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(10632..11855)
                     /locus_tag="TV186_001131"
     CDS             complement(10632..11855)
                     /locus_tag="TV186_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1532529.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
     gene            complement(12080..13051)
                     /locus_tag="TV186_001132"
     CDS             complement(12080..13051)
                     /locus_tag="TV186_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL1532530.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(13364..13804)
                     /locus_tag="TV186_001133"
     CDS             complement(13364..13804)
                     /locus_tag="TV186_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1532531.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(13801..14736)
                     /locus_tag="TV186_001134"
     CDS             complement(13801..14736)
                     /locus_tag="TV186_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1532532.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(15174..15587)
                     /locus_tag="TV186_001135"
     CDS             complement(15174..15587)
                     /locus_tag="TV186_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL1532533.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(15685..16440)
                     /locus_tag="TV186_001136"
     CDS             complement(15685..16440)
                     /locus_tag="TV186_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL1532534.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(16445..18940)
                     /gene="gyrA"
                     /locus_tag="TV186_001137"
     CDS             complement(16445..18940)
                     /gene="gyrA"
                     /locus_tag="TV186_001137"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL1532535.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            19132..20115
                     /locus_tag="TV186_001138"
     CDS             19132..20115
                     /locus_tag="TV186_001138"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL1532536.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(20320..21687)
                     /locus_tag="TV186_001139"
     CDS             complement(20320..21687)
                     /locus_tag="TV186_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL1532537.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYDVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(21937..22539)
                     /locus_tag="TV186_001140"
     CDS             complement(21937..22539)
                     /locus_tag="TV186_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL1532538.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(22540..23517)
                     /locus_tag="TV186_001141"
     CDS             complement(22540..23517)
                     /locus_tag="TV186_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL1532539.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(23520..24779)
                     /locus_tag="TV186_001142"
     CDS             complement(23520..24779)
                     /locus_tag="TV186_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL1532540.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(24791..25222)
                     /locus_tag="TV186_001143"
     CDS             complement(24791..25222)
                     /locus_tag="TV186_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1532541.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(25236..25829)
                     /locus_tag="TV186_001144"
     CDS             complement(25236..25829)
                     /locus_tag="TV186_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL1532542.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(25801..26649)
                     /gene="prmC"
                     /locus_tag="TV186_001145"
     CDS             complement(25801..26649)
                     /gene="prmC"
                     /locus_tag="TV186_001145"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL1532543.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(26646..27728)
                     /gene="prfA"
                     /locus_tag="TV186_001146"
     CDS             complement(26646..27728)
                     /gene="prfA"
                     /locus_tag="TV186_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL1532544.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(27770..28339)
                     /locus_tag="TV186_001147"
     CDS             complement(27770..28339)
                     /locus_tag="TV186_001147"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL1532545.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            28526..28711
                     /locus_tag="TV186_001148"
     CDS             28526..28711
                     /locus_tag="TV186_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL1532546.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            28766..>29140
                     /locus_tag="TV186_001149"
     CDS             28766..>29140
                     /locus_tag="TV186_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1532547.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         8613 a         6030 c         5495 g         9002 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tactttacta tttacaggat
      361 aacaagcaaa acctattaca atattattga aagataagac gagtggcgat ttttcgccac
      421 ttttttgata aaataatatt atgattaaag ctggaaaaat ttatattgtc gaagatgacg
      481 ctgctatctt aacaccctta aaagagcatc tgagtcagaa ctaccaggtt cttaccgtct
      541 ctaactttag agacattaag caagaggtga ttgattataa accggatatc atccttatgg
      601 acatcacctt accgtttttt aacggctttt actggacaac agaaattcgt aaaacgtcaa
      661 cagtgccaat tgtttttatc tcaagcagta atgatgagat ggatacggtc atggcactta
      721 atatgggggg agatgatttc atctctaaac ccttttctct aaccatttta gacgcaaaaa
      781 tcgcagcctt tttaagacgc tcacagcaat ttagcagtga tgatgtgacc atagatcaat
      841 ttaagctaca ttttgatggc accttatcta atggcacaga tagcattcat ttatcgccaa
      901 cagagcacaa aatcttaacg attttattta ctcacccgca gcaaattgtt tcaaaggagg
      961 atattctagc aaggctttgg gaaaacgaga gctttattga tcaaaacacg cttaatgtta
     1021 acatgacgcg tctacgcaaa aaaatatcag ctattggttt tgactgtatt cacacagtga
     1081 gaggagtagg ctatattatc aaatgataag agcatttttt aaggaatatt attcctggta
     1141 tatccagtat ggggttgtta tggctggtta tctgctgatc ttttggcttt ataggcttcc
     1201 tttaggctat tttaaagtga ctagcctaac catactaacc ttgctaatat tgcaaggttt
     1261 tggaaactat attaggttca aaaagaagat gaagatttta caagaattta tttatgtaaa
     1321 agaactagat cagctgcact cccctagcga acaagcctat aggtctttga ttattaagct
     1381 taaggaagca gaagcagagg tagcactgta ccaacttaac aaccaaaaga atacagaagc
     1441 actgattaaa atgtggtctc accaaatgaa gcttccccta gcggctatgt ccttaatgct
     1501 tcaaaccaat catattgata ttaaggatta tcagattcag gttctacgct tggagcatta
     1561 cctcaacaat ctattaagct atttgaagtt taaccagcat agtgatgatt ttcggtttca
     1621 ggtttgctct gtaaagcagc ttgtgacctc agttatcaaa aagtccagcc agacttgtat
     1681 cgctaagggg attagcattg cagttgatgg cgattggcaa ttgagcactg acaacaaatg
     1741 gctgtcattt gctctgacac aaatcattga caatgcaatc aaatattcta agccacaagg
     1801 ccacatcaaa gtcagcatta aggaaggcag tatttttata tcagataatg gtattggaat
     1861 actagaggaa gatttgccac gtctgtttga agaaggcttt actggctaca atggccatga
     1921 gcatcaaaag gcaactggtt taggcctctt tatgacaaag caaatccttg ataaattaaa
     1981 tttaaacata actatttcca gtcaagttga ccaaggaact ttagttgtaa ttcaaaaaaa
     2041 gcattctaaa cagaccaaat tctcgacttc tttgctgtaa aaaataacag ctataaatcc
     2101 ctataatagt gacaaagagg attaaaacat tgcaaaaaaa gactgaaagt acagattaca
     2161 taattttagt tatgtaaatt tataatttat ctagggcatt tttttgctca tcgttaacaa
     2221 tatgagtata gaggtctgta acttgggtcg aggcatgacc aagctgatga cttactagga
     2281 cctgtgactt tgtagtatca taaagtctcg ttgcaagcgt atggcgtagc ttatgaggag
     2341 ttacacgaat tttaaagcct tcagaatatt tacctaccat tttttcaatg cttgaggcat
     2401 ctatccgatt ggggagccca cgataggctg ttaaaaagaa ggctacatcc tgtttttctg
     2461 cttgatagcg gtcttttcga actgataaat aggcttctaa atgaggcttg gcaaaagcag
     2521 caacattgac cgaatctctc ttacctccct tacgggtaac ctcaaccagc atcatgttga
     2581 ggttgacatc cttaaggtct aggttaactg cctcggataa ccgaatacca gatgccagca
     2641 gtagggcgat aatggctagg tcgcgttctt tattttttcg gaaagaagcc tttgcccgat
     2701 ttgacagctt atattcatat tctttatcca catagtctaa aaatgccatc gtctcatcgc
     2761 ctaaaaaaag cttttgttta atattttcag ccctggctgc taaggtttct cttttctttt
     2821 tggttgccac ctttttcatg acatttcgat aaaaataagg ctctccatgc tcattttcaa
     2881 cctcctcagt aaggtattta tacaagctgg atagtgcaga aagggtacga ttaatggtgg
     2941 tttgcgatac ccccttttta gttgaataga tgttcaagga aggacgctca cgaagataga
     3001 gaataaaggc ttccatatcc tttttactca aatgctccag agtagtcaag tccacatcag
     3061 caatcctagc agcttttgat agatcagaat caattaacca ctcaaaaaag cgtttgtatt
     3121 ctttcaggta ttcgtacaag gtcgtaaagc tataaggaac agatagctta gattgataat
     3181 aatcaaggac ataccaaggc atgatgtttt tgtattcttc aattttagta agtagtaaat
     3241 cacgtttcat aataaattct cacaatgttt cgtcaacaaa tgaattatcc attggatatc
     3301 agactgatag tagtatatca catcttgggg tatttttcaa gaaaattata gtttttcgga
     3361 aagatataaa attatttaat agttattttg ctaagctaag gctgttttat ctgctacgat
     3421 gctgcttaaa aatatagtat ttactaacaa taaaattcaa gctaatcatt atggcttggc
     3481 tcaaaatgct ttcaacagaa ttaatgcttt cagaatcatg ttcaacaagg cttccaatga
     3541 cctctgggta tttttcgact aataaatagg ctaatagcat atctaagcct aatgttacta
     3601 ctctagctag gaaaaacatg gcaaatctaa acaagcgttt ttcagaagtt tgcttaaaaa
     3661 catagctatc gttcatcaag aaggcagcta tgatcgctat aatattggca aagcctgctg
     3721 atatggtggc ctgatgtaac catgaataga tgacataccg aaaaacaaaa taaagaatgg
     3781 ttgttagaag accagatatc aggtaatgac tgatttcaag tgataatttt tgtttgctaa
     3841 gcatttttct ttcctatgtg tatttatctt gactgttata ttttgatgga tctatataag
     3901 tataacatgt ttggcattaa acctaagaca gcttactgtc ttttcgatat aaacataaaa
     3961 agcttgaata ttcttataag ctatgttata ctctggtaaa gttaatactt tactagagta
     4021 tactgacaaa ggagatttat gctgatgttt tctggtattc aattaaaaac agcacgttta
     4081 tcaaggcata ttagccaaga acagctagga cagcttttag gagttaataa aatgactatt
     4141 tccaattggg aaaaggagaa aaatagacca aatcaaaagc attttgaaga gcttgtgagc
     4201 atttttcaat tacctgctga gtacttttat caagaaaatc gtcttttact tccctatagt
     4261 cagttaagcg cctctaataa agaaaaagtt atcagctatt ctgagagctt acttgaacaa
     4321 aaagaaaaaa taattgcttt accagctaag aaaaagacac tttaccctta tcgtgtttat
     4381 gaaaggttgt ctgcagggac tggctattct tactttggtg atggtaattt tgatgttgtc
     4441 ttttacgatg agcagttaga ttatgatttt gcttcatggg tttttggtga ctccatggag
     4501 ccaacctatt tgaatggcga ggttgttctc atcaaacagg atagctttga ttatgacggt
     4561 gctatctatg ctgttgagtg ggaagaacaa acctatatca aaaaagtata tcgtgaagaa
     4621 aatggtctgc gtttggtttc attgaacaaa aaataccctg ataaattcgc ttcctttgat
     4681 gacaatccgc gtattattgg aaaaatcatt gccaacttta tgcccttaga tgtataagcc
     4741 tttgtattag cttaaaagca tgactgttgt acaaccaaac tcattgcatg acattggtgc
     4801 attatttttg aagtggcttc tacttctttg atttactttt ctgcattaaa aagcccatta
     4861 aaggtttttg aaacttatta cttagacaaa ggctctatta aaaatcataa ccaaccggtg
     4921 gtggtttatt tgtcatgtac cttgcatttt gtgacagact tcataaaacg aacaaaacac
     4981 atcgctaaaa gattttacca tcttaaagtt atgtgttttt tgtataaaaa cttatctata
     5041 tgcttgatta accaactgag ataaatagat tattatttca tagagaagtt tgttatctaa
     5101 tccaaataat cgtattatcc tcttaagttc ctcaacatta taaccatcac aatctgttgg
     5161 cagtttattt ttttcaagcc acttatcaac cactgctatt cccaaagaaa ttgaaaaatc
     5221 tttttcttta tcaaacttac acaattccac tgccaaagtc aatacaaaat tcctgtgaat
     5281 attatcgtaa ttttcatcaa ataattgcct ttccaaaccc acaatagata gccgactaaa
     5341 tatgtatctc cctatttctt cgtcaatacc ttcagtagcc ttaatagctt cttggacaac
     5401 attattccag aaagcatttt tattacgctc ttctataaaa gttttaagtt tcattttgaa
     5461 aatatcagta atttgaccaa ctgctttatc aataacctat gaaacaatat tcttcatcat
     5521 tatgattttc tcctcgtata cataaataat tgtatctttg ctatataatt gtggtatctc
     5581 ttcaatcaac caatattgtt cttaaactat tccctcaaaa gccttccacc aaaacgatgg
     5641 aaggctttta aaccattcac ctaaattcaa caactccctt ttgaacttgc tattttagct
     5701 ttttagtatc aaagcagtat cactcaagag ttttttgttt ccacaaaccg caaaaaccca
     5761 ctgttttcaa cactttcatg gcagtaatat atttgcttct gtcactccca ctcaacggtt
     5821 gctggtggtt tgctggtgat gtcgtagaca atgcgattaa cgtggtcgac ttcattgaca
     5881 attcgaactg agattttctt tagaacttcc caaggcaatt gggcaaagtc tgctgtcata
     5941 ccatcaattg aggtgatagc acgaatagcg atggtatagt cataggtgcg accatctccc
     6001 ataactccga cggaacgaac acctgtgtta actgtaaaat attgccacac atcacgctca
     6061 agtcctgctt tagcaatttc ttctcgaagg atagcatctg actcgcgaac tgtttcaagc
     6121 ttttctgctg tgatctctcc catgacgcga atggcaaggc ctgggcctgg gaaaggctga
     6181 cgccagacga cttcatctgg cataccaagg gccgtaccaa gagcacgaac ctcatcctta
     6241 aagagtgtat tgaggggttc gattaattca aactgcatat cctctggcag accaccaaca
     6301 ttgtggtgag attttatcgt ttgagcagtt tctgttccag attcaatgat gtctgtgtaa
     6361 agcgttcctt gtgcaaggaa gtcaacgccc ttaagcttgc tagcctcgtc atcaaagacg
     6421 taaacaaact cattaccgat aattttacgt tttttctcag gatcctcaac gcctgcaaga
     6481 agatctaaaa agcgctttga ggcatcaaca cgaataatat tgagaccaaa tcttccacca
     6541 agcatttcca taacttggtc accttcattt ttacgaagaa gtccatggtc aacaaagata
     6601 caggttaatt gatctccgat agctttttgt aaaaggacac caacaactga agaatcaaca
     6661 ccaccagaca aacctagcaa aaccttacga tctccgactg tttcgcgaat tttagcaatt
     6721 tgcatgtcaa taaaattatc cattgaccaa tcaccacgtc caccacagat agagatagca
     6781 aagttcttca aaatatcatt accatagaca gagtgtctta cctctgggtg gaattggata
     6841 ccgtagagcc tcttttttgt attttccata gcagcgtaag ggcaatcgtt agaatctcct
     6901 acaagatgaa agccctctgg gatttctgta acagcatcac catgactcat caaaacaagc
     6961 tgctcatctg gagtgcccgc aaataatgct gatgcagaac gtaaacgtaa tgatgattga
     7021 ccatattctc ggtgacctgc ttgaccagct gggactacct tacctcctaa ggtatgtgtg
     7081 attagctgca tgccatagca aatccctaaa attggaatcc ctaattcaaa gatttcagga
     7141 tcaataccaa aggcatcagt tgcataaaca gaatttggcc caccagacag gacaatcccg
     7201 attggattga tgtcacgaag ctcttgcgca gtgatgtgat ggcttttgag ctcagaaaaa
     7261 acaccaaact cccgaatacg tcttgcaatc agttgattgt actgactacc ataatcaaga
     7321 acgataattt tttgaatatc attcaacatt gaaatttcag tcattataac cctttcatta
     7381 tataccagaa ccttgttagc tgatagtttt caattaattg tagcatattt tcactaaaaa
     7441 ggcattagct tttcaggtga tgtgatgaaa aaataagctt tttgcagaga tattaaaatg
     7501 aatgacctca actatcttat gtatgactac tattgtcagt cttagcatga aaaagctgat
     7561 tgatgatgag tgtttttggt aataattggg ctgctattta ggctgaaaat atgataaaat
     7621 aaaaccatca tcaccctcaa ggagtaaagc atgctgccag cttatataaa aattcatgac
     7681 gctattaaaa aagacatcga aaaagaagtt tggactattg gtagtcgcct gccaagcgaa
     7741 cgagatttag cagaacattt tgaggtcagt cgcatgacgt tgcgtcaggc aataacactg
     7801 cttgtagagg agggaattct agaaaggcgt gttggtagtg gtacttatgt tgccagccat
     7861 cgcgtacaag agagaatgcg tgggaccact agctttacag agatcgtgaa ttctcaggga
     7921 cgtaagccat cttcaaaact gatttcctat caacgtcagc tagcaagtga tacagaaata
     7981 aatcaattgc acttagaaga atcagattac gttattcgaa tggagcgcat tcgttatgca
     8041 gataaggttc ccttagttta cgaggtagca tctattcctg agaaatttat taaaaatgtc
     8101 aaaaaaactg atattacaga gcactttttc caaaccctaa cctcaaacgg ttatgaaatc
     8161 ggcaaaagtc aacaaaccat ttacgcgaaa atagccagtg agcgtgtcgc ctcttatcta
     8221 gaggtcgcta aggggcatgc tattttagca ttgactcagg tttccttttt tacagacggt
     8281 aggccctttg aatatgtgcg tagccaatat gtaggtgatc gctttgaatt ttatttagaa
     8341 aataattaat cataagcaat gatgtttaaa taacattgat aggaagtggc tcaccacttc
     8401 tttttttcaa cacttgtcaa gtatatcaat atttcaagaa cagttattaa aacaagctac
     8461 tattatcctc atttttgctc taagaaagct tcctgataaa aggctgatcg ctatcattta
     8521 ccactgttaa aaatgctcat gatgtgataa aatgaagatt atggaaattg aaaaaacaaa
     8581 ccgaatgaat gctctttttg aattttatgc tgccttattg actgataaac agatgaacta
     8641 tatcgagctc tattacgctg atgattatag tctggctgaa attgctgaag aattcggtgt
     8701 cagccgccaa gcagtttatg ataatattaa gcgcactgaa aaaattctgg aagcctatga
     8761 aatgaagctt catatgtatt cagattatat tgtacgtagt gaaatatttg atgatattct
     8821 tgcaaaatat cccagtgacc actatttacg tgacaaaatt tccattttaa ctagtattga
     8881 caacagagat taagaggagt tatagctatg gcatttgaaa gcctaaccca acgtttacag
     8941 gacgttttta agcacattcg tggtaaaaaa accttatctg aagccgatgt tcaggaagtg
     9001 accaaggaga ttcgtctagc cttattagag gcagatgttg cacttccagt tgttaagacc
     9061 tttatcaagc gtatacgtga gcgagctgtt ggccacgaaa ttattgatac ccttgatcca
     9121 acgcaacaaa tacttaaaat tgttaatgag gaattaactg gtatcttagg atcagaaacc
     9181 gcggagcttg ataaatcacc taaaatccct actgtcatca tgatggtggg cttgcaggga
     9241 gctggtaaaa cgacctttgc aggaaaatta gccaataagc tcatcaagga agaaaatgct
     9301 cgtccattga tgattgcagc agacatctat cgtccggctg ctattgacca gttgaaaacc
     9361 ttgggacagc aaataaatgt tcctgttttt gatatgggga caaatcattc agcagttgat
     9421 attgttgcca atggtttggc acaggcaaaa gagaaccgtc atgactatgt tttgattgat
     9481 acggcaggac ggttacaaat tgatgagaaa ctaatgggcg agcttcgtga ggttaaagca
     9541 ctagctaaac caaacgaaat ccttcttgtt gttgacagca tgatcggaca agaagctgcc
     9601 aacgttgcct atgaatttaa caatcagctc gatatcactg gagtagtgtt aacaaagatt
     9661 gacggtgata ctcgtggtgg tgcggccctt tctatacgtg aaataactgg taagccaatc
     9721 aaatttaccg gaactggtga aaaaatcacc gatattgaaa ccttccatcc agaccgtatg
     9781 tcaagtcgta tcttgggaat gggagacctt cttaccttga tcgaaaaagc aagtcaggaa
     9841 tatgatgaga aaaaatcatt agagcttgcc gcaaaaatgc gtgagaatac ctttgatttt
     9901 aatgacttta tcgagcaatt agaccaagtg caaaacatgg ggccaatgga agatctgtta
     9961 aaaatgattc caggtatggc aactaatcct gctctagcca atattaaggt tgacgacaag
    10021 caaattgctc gcaagcgtgc tatcgtttct tctatgacac ctgaggagcg tgagcagcca
    10081 gagcttttaa caccaagtcg ccgccgtcgc attgcagctg gatcaggtaa tagtttcgtt
    10141 gaagtcaaca aatttattaa agattttaac caagccaaag ccatgatgca gggtgtcatg
    10201 tcaggtgata tgactaaaat gatgaaacaa atgggaatca accctaataa cctccctaaa
    10261 aacatgccaa atatgccagg aggcatgcct gatatgtctg cccttgaagg aatgatgggg
    10321 caaggtggtt tacctgacat gtctgcattg ggtggtgata tggatatgag ccagctcttt
    10381 ggaggtggtc taaagggtaa gattggtcaa tttgccatga agcaggccat gaagcgtcaa
    10441 gctaataaga ttaaaaaggc caagaaaaaa cgaaaataga ctaaaagaat ggttgccttg
    10501 tattctgcct ctaatcgtta gatgctattc taatttggag tgcaggtcag tagcgaccat
    10561 cttttttata aatacaatca ctagatcttt ggttctaacc attaaacatg atatcatttc
    10621 actattagct gttagtgcct gtgctttaat tgctttctga tcttatatag caaattagcc
    10681 aagtgataaa aaggactgat tgctaggttg aattctccaa taaactcttc gatagttgga
    10741 ctgaaattgg acttaaatgc tgtcaatccg tccttgaagg agccatcaat gccgcccata
    10801 ttcgcccaag ctatatcatc atgataggca tccataaaga ctttaggata aagcaggtac
    10861 tgaggataaa actttttaaa gtcatcattc atgccagcat agagcatttc catcgtgttg
    10921 ccatatgaaa tcgataaaat gcccgcaatg acaacctcat ctggatattt atccaagaag
    10981 tccttgaatt ctgatagata acgctgaagc gattgctttt gatctgttag tctagccagt
    11041 cgcttttttt gatgcgcttg cgtttgagca agctcttgtt caacagcttt cagctgaagc
    11101 tcgtaattct tgagtttttc tggaagatta acctttgcta aatgcaaata agcattgtcg
    11161 ccataagtcg tcatcagctg tctaaaataa gcttcgtttc ttagagcaac tccttttctc
    11221 ttttcagtta aagagataag gtcagcaaat gtatggagat cagactgatt acctcgataa
    11281 gctatcacgc cacgttgcct agcatccttc atcaatcgct tggtatgctt aggaaaggac
    11341 gcttcaatat cagcattagt gtaacaattt gcttgaaaac gcggctgaat agtatcagat
    11401 agcttggttg ttgggcctgt ccaatgggca ccaaatcgct ttaaatgctt aataatggtc
    11461 agagccttgg aattatcagg tgctttctca ccaagctgat gctgctttag cagaatcata
    11521 ggatcaaatt taatcaaaag agctcttttt ttcttaccat atgccttcaa ggttttaatc
    11581 gtaaatgcca ctagatcagc attggtatag tccatcactg gacctcttgg aatataaatc
    11641 atcgtcatac caaacggcaa aggcttaatc agcaaggaca tagaagccac ctgattatct
    11701 ccctgaaaaa taccgatgcg ttcattttgc cactgatttt taacagctgc ccatgagctg
    11761 ctctgcaaga ggttaacctg ctggtgctgt ttgacaaatt ggtcatgctc ttgagctgaa
    11821 ataccgattt ttgaattaaa agctacattt atcatcatat ttcctcatct ttaagtatct
    11881 aaatatctga tcttgaaata gatctgcttc tacttaattt attcgaaaaa tagtttgaaa
    11941 aataattgct ttttttgatt ttcaatttga ttatttttag ctgctcaaat gaataatcga
    12001 tttcggttta aataagttta aaaaatagga ctaattccta atgaaatcag gaattagtcc
    12061 tactactttt atctatttat cagttaccca ttaggctgtc aatcaatcct ctaaagaaat
    12121 caataatttg ctgaaggatt ccctgtccag tctttaaggc ttcagtagca tcaaagttca
    12181 cgttgatatt tttaaaggta gatccggcct tttcaacaat actatccttt aaagcattca
    12241 gcgttttggt gaagttttca ttggaaatca cgccactatt tgagaggtta agcgcgaaat
    12301 tgataataag gttaatctga tcaggtgtta ctgccttggt taacccataa tgatctaagg
    12361 tttctgttac aatttggcgc accttttcct cattaacccc ttctccagcc tttgcgacag
    12421 cagctttaat atcagtaagc gcaacattta gcttatctgc atcatagcct gttttacctg
    12481 cattttcggt attgatatta gatagggttg atagctcctc ttgtgccagc ttcttgtttt
    12541 cctctgggac tttggcacca tttttttcga gtgaataata aataccggct aaagctgatt
    12601 ctccagtaac tgggattggt gcagctacag taatattggc atgctcaatg cccaaggtca
    12661 cagcggcgtt acgatacata tcttgcgtca ccttagtgat attttcaggt gttacaatag
    12721 ttaccttaag cgtttcttta gctcccagct tttgaatcct aactgaggaa taaagctgta
    12781 ggctcggatc atctgctaca ttcatgatac tagcataggc agttgtattt agggtgctta
    12841 atttgttatc agaagcacta ttgtagtgaa gcaaggccaa ggtttgctct ctttgctcag
    12901 cagacagtga atagcctaaa acgtaatcag gctgaacata ggtttcatca attacctgtt
    12961 gaacattatt agctgcagcg tgtactgttt gaagcataaa taccgaagcc aaagccatac
    13021 tggctgctat taatttcttt tgataagtca tttttctacc tcttttgtgt tataaatttt
    13081 cctttacgag aatcctccag aaaagacgat taaagccaaa gtatctaggt gcctagtaag
    13141 accgttttac ttagctctgc aaagggcaat attcctagtc tttttcaaaa tctaacgcct
    13201 ctattgtagc atttttacct caataagacg attaaaaagc tgaaacaaag catagctaga
    13261 atggccaagc actattttta caacaaaaaa actagtgcat aatggcagct tagatgtagc
    13321 tactatcact agtccaatga ttatcttatg cagcaaccag tctttatgat ctgaggtttt
    13381 cttgatggtt attgtccttt aaatagaaat aataatgatc atcagttttg atgacatagc
    13441 catttttaac ctcattaatc acgtcctttt gatcaaactg gtagtcctta ggcggtaata
    13501 actctgagga aaaaaggcta tcataaggca cctcaccatt gtaaaaatgg taatggtcac
    13561 catgagaggt aacaaaacca tcatccgaga tagacacaat aatttgctct gctgctatcc
    13621 cctcttcctt gctaacttca ttaggacttt tgtcagtctc tttctttaag gctttgcacc
    13681 ttttttccaa ttgatgagat gattttagct tcttgcctgt gctatcttgg gctttaaagt
    13741 cacaagcgga caaaggaaat aatagtaaga tagtgaataa cgataaataa gcttttttgg
    13801 tcatgtttca ctctccaata cacgatatag tgtttctaaa ttcattttta aatgctctag
    13861 ataagttttt tgatcagctg gaaccacctc aagcgggctt aggatatcaa ttgctacacc
    13921 gttactttga gccaaggttt tggctagctt atctgaagca ttttcttcga cgaaaatcgt
    13981 cttcacatca tattttttga taaagcggtc aatttgagct aattggcgag gactaggctc
    14041 ttgctcagga gatatccctg caattcccaa ttgctttaga tcaaatctct tagctaggta
    14101 ggaaaaggct gtatgctgtg tcacaaaggt tttcctacct agagattcaa acttttcctt
    14161 ataggtcttc actaattttt gagccttagc cttaaaacgc ttagcatttt gcaaataaac
    14221 tgccttgtga gcaggatctt tttgactcaa taaagctgca atctgctctg cctcttgact
    14281 agctaagata ggatcagtcc aagtgtgagg atcatacaag gcatcggtat tcattccttt
    14341 ttttatggtg aagtgctcca agccttgaac cttgtctaat gttagatgtg atgtcccctc
    14401 catgactgct aatccctttt tttccagctg tggtgccaaa tccgcagccc aagcttctaa
    14461 tatcttggaa tggtaaataa agacatctcc atcgtaaacc ttagcaacaa ctgtcggact
    14521 tggctcatac gagtgtatgc tagtgttttg ggcaatgacc tgaacatcat ttaaatcccc
    14581 gcaaatctcc tttgtcatag cataaatagg ataaaagctt gtttttatga ccaaaccggc
    14641 cttcctactg ctagagctct gatgacaggc tgatagaccc aaaagtactg ctaatagtcc
    14701 tactgcgaca attgttttct tgaatcctct aatcatatct actctcttaa ctagttaatg
    14761 acctaaaaag gataccatga tttaactgaa atgtcaatat tttatcattt tagcgcacga
    14821 cgtacacgca tgaagaaaat gcatgtaagc cttttttagc cccatgcatt ttttaatcta
    14881 tttctagcgt tttgacattg caatatcatc agtttgtcaa tttcaatgtg atgacttcat
    14941 cacattttgc taaaaaggcc atagtgatga taaaaaaccg ctaccagaaa gcgtaaatgt
    15001 cttcttgctt ttgtcgtgat tttagtgaac cgcctaccaa ctgaactgat gctggcttaa
    15061 ccatttcctg gccaccatca aaagcctgcc tctcaattaa caagcttact caaggaagag
    15121 gtgactgagc catgcatccg tcttagttat gactaacagc ttatcttggc atttcattca
    15181 tgtaattcca gtggcaggcc atcaggatca aaaaagaagg tcatcttctt accagtataa
    15241 tcatcatacc taagaggctc gacagcaatg cccttagcca ttaattgttc aatataagct
    15301 tcaataggct taacatgaaa agctaaatga cgaagcccac aggcctcttt gtcatattcg
    15361 ggcctaccga tacgcttagg cggtgcctga taagctggat cagtcttttt attgccaaaa
    15421 atctctaatt caatggctcc acattttaaa tccaatttgt aatcatgtct atcaggccgg
    15481 tgattttcac gaataatctc aaagccaagc ttattgacat aaaaatcctt agagacctca
    15541 taatccgaaa caatgatagc aatatgatga atagccttaa gctccatatg atttagttcc
    15601 tttattaaat aaaaaaagtg aaacaaagca atgccaagat tactttgttt cacccctcgt
    15661 agcgacccct cgcctagatt aggcttaggt tgacatctga ttgtaagagt gattaaaggc
    15721 cttcaaaaca tcgtcaggtg ctttgttaaa ctcatactcg tttttgattg ctcctttgac
    15781 aatgattcgc tctgttgcct cataatccgt acaggtgacc aaggttacct cctttagccc
    15841 tggtgtgtca ttgataacat ctattctctc aggtgtgacc gtaaagacgg cattgatctc
    15901 gtactcgtaa atacgctcct tatctgtaag gtaaatagac atcccttctt ttgctctttc
    15961 aagcggtgag aataacattt cagaagagcc tgttagtcca aaaatatgat gactggctaa
    16021 ggagtaattg ttttctcctc ccataacctg gtcctctttc atggtaccag caccgtatat
    16081 aagctctgtg ttgccaagcc ctttaaagat tggtaggtta ataccaagct ctggtatggc
    16141 aatacctcct attactggaa gctgctgggc gtccatttga gcctgtaaga cactttcggt
    16201 gctaactggc tgaactgctt gaaaatcaaa gcttgacttt gcttccttat tctttttaat
    16261 cgtctttttt gaaacctttg taacttgata tttattagaa ttccaagcaa tcagggtgtt
    16321 tctaatgggc ttgttaaata acaaggctaa gcctatgatt aacaataaga cgactagaat
    16381 acctctagca aaggacatct ttcttcgttt ttgtcttctc ctgtgggttc tttttgccat
    16441 tcatttactc cttgctagaa tttattggtg cttctgttaa agctgtatca gtctgagcga
    16501 ttgctgttgg atcgttgtct tcagcctgta ccaaggtaaa ggtaacaatc ttagaatctg
    16561 tatctagcct cataacctta acaccaagtg ttgaacggcc agtctgagaa atacttgaaa
    16621 cattggtacg aataatcaca cccttcgttg tgatcaccat aatatcctca ctgccatcaa
    16681 cagtcatcag gccagccaac tggccatttt ttgcggtgat attagctgtt ttgattcctt
    16741 ttccacctcg acccttagtt gggtattcgg ctgcactggt acgcttacca tagccatttt
    16801 cggtgatgac taagacctct tgcttgtcat tgatacgaga agctccgaca acccaatctt
    16861 cctcacgaag cttgacacca cgaacacccg tagcgctacg ccccatgcct cgaatggtag
    16921 cttcattaaa gcgaacagaa taacctgatc ttgttccaat gataatatct tcctgaccat
    16981 ttgtcaagag aacattaatc agctcatctc cttccttgag attaagggct cgtagaccat
    17041 tctgacgaat attgctaaac tctgatacct cagttcgttt gacaatccct tgctttgttg
    17101 taaagaagaa atatttatca agaatgtctt cttttttagc attgataatt gtttgaatgg
    17161 tttcaccatc atctagcttt agtagattga taacaggaag tccttttgca gcacgtccat
    17221 attctggaat ctcataggcc tttaagcgat agacgcgccc aaaattggta aagaaaagca
    17281 atgtgtcatg tgtacttgtt gagacaagct cacgaacaaa gtcatcgtca ttgacacctg
    17341 ttccctgtac accacgacca ccacgctttt gagatcgaaa ctcgtcttga gcaaggcgct
    17401 taatgtagcc attgtttgat agggtgatca aaacatcttc ttcctcgatc aaatcctcat
    17461 cttctaatga caatacctca ccaatcatca attctgtgcg gcgaggatta gcgtacttgc
    17521 gcttgatctc ctccatttct tccttgatga tggcttcgat acgctctggc cttgccaaaa
    17581 tatctgccaa atctgcaatc aaagccagta ggtcatcgta ttctgattga attttatcac
    17641 gttccaagcc ggtcaaacgg cgaagacgca tgtctaaaat agcctgactt tggcgttcag
    17701 acaagtcaaa acgagacatc aattctgctt gtgcgataat atctgtctcg ctattgcgga
    17761 taatggcaat aacctcatct agatggtcaa gagcgataag taagccctct aaaatgtgtg
    17821 ccctagcttc tgccttgtcc ttgtcaaatt gagtcctgcg tgtaatgacg tccttttgat
    17881 gtagaatata attatcaata atctgtctca gtgacaagat tttaggaatc ccgccttcaa
    17941 tggctagcat attgaagcta aagtttgtct ggagacttgt caatttgaat aggttattta
    18001 aaatcacatt agcagatgca tcgcgacgga cttcaatgac aaatcgtacc ccttgtcggc
    18061 ttgattcgtc acgaacagct gtaatgccct caatacgctt ttcttgggct aagcgaacaa
    18121 tatgctcatg gacctttgtt ttattaatgc cataagggaa ttctgtgacg acaatccgct
    18181 cccgtcctgt actagtggtt tcaatctcgg tgcgtgaacg caaaacgatt gatcccttac
    18241 cagtctcata agccttatga attcctgaac gtcccatcac caaggcacct gtaggaaaat
    18301 ccggccctgg aagaacctcc attaaatctc tggtagtgca gtcaggattt tccatgacca
    18361 tcttaacagc gtctatggcc tcagctaaat tatgaggtgg aatattggta gccataccaa
    18421 ctgcgattcc ggtggcacca ttgaccaata aattggggaa gcgagccggt aagactaagg
    18481 gttctctttc attaccatcg tagttatcct gaaagtcaac agtattttta ttaatatcct
    18541 ttaagagctc tagcgcgatt ttgctcatac gagcctcagt ataacgctga gccgcagcac
    18601 cgtcaccgtc catagaacca aagtttccat gaccatcgac aagcatgtga cgatagctcc
    18661 accactgggc catacggacc atcgcttcat agatggacga atccccatgt gggtggtact
    18721 tacccatgac atcaccggta atacgagcag attttttatg tggcttatca ggtgtgacgc
    18781 ctagctcatt catgccataa aggatacgac gatgaacagg ctttaagcca tctcgtacat
    18841 ctggaagtgc tcttgctaca ataacgctca tagcataatc aatgaaactc gttttcatct
    18901 cacttgtcag attgacgtca actaaatgtt tatcttgcat ttaaggaatg ctccttttct
    18961 agtcaatact cttttaatta taccataaaa tccttatttt ttctgattgg aaacgctgtc
    19021 cgaaaacaat tttcataatt tggtcgaata tcatgacaaa gacattaaaa tgtgttaaaa
    19081 taagatcgta tgagcaattt gctctaacta aaatgaagga gatgtttaga aatgactgca
    19141 actaaacaac ataaaaaagt catcttggtt ggcgatggtg ctgtaggctc ttcttatgcc
    19201 tttgcactag taacccaaaa tattgcccaa gagcttggta ttattgatat ttttaaagaa
    19261 aaaactcaag gagatgctga ggatttaagc catgcgcttg cctttacctc ccctaaaaag
    19321 atctatgctg ctgattatgc tgactgtcac gatgctgacc tagttgtttt aacagctggc
    19381 gctcctcaaa agccaggtga gactcgtctt gaccttgttg agaaaaatct acgtattaat
    19441 aaagaagtgg ttactcaaat tgtggcctca ggctttaagg gaattttcct tgttgctgct
    19501 aatccggtgg atattttgac ctattcaacc tggaaattct caggtttccc taaggaacgc
    19561 gttatcggtt ctggaacatc acttgactca gcacgcttcc gtcaggcact tgctgccaaa
    19621 attggtgtag acgcacgttc tgttcatgcc tacatcatgg gtgagcatgg agattcagaa
    19681 tttgctgttt ggtcacatgc taatgttgca ggggttggat tgtacgactg gcttcaagct
    19741 aatcgtgacg ttgatgaaca aggcttggta gacctcttta tctctgtacg tgacgcagct
    19801 tactctatca tcaataaaaa gggtgctacc ttctatggta ttgcagtcgc cctagcacgt
    19861 attacaaaag ctatccttga tgatgaaaat gcagttcttc cactttctgt tttccaagaa
    19921 ggccaatacg aaggcgttga ggattgctat atcggtcagc ctgctattgt tggtgcctat
    19981 ggtattgttc gtccagtcaa tatcccattg aatgacgctg agcttcaaaa aatgcaagct
    20041 tcagcaaacc aattgaagac tattatcgac gaagccttct ctaaagaaga gtttgcgtct
    20101 gctgctaaaa actaattaaa aaatgaatgt gttagatctt gctctaacgt tttggaatca
    20161 ctacaaaaag cctaatccaa tcggataggc ttttttcatg cgtctaacag cgaggtgcaa
    20221 gacaaagcac gctttcatta agcatcgtgt gtgctatgct tatagtctta agtcacaaaa
    20281 aagacaacca gctttatgag ctggctgctt attagcttgt tattcagcac caagtgctgc
    20341 cattgtaatg tagttatatg gcttgttaaa gtgcggtaag aagaaaatat cagtcaaagc
    20401 taatttctca atggtcactc cttcttggat agcaagtgag aacatatgaa ttcccattga
    20461 aatatcttca tgtgaggcca tttgagcacc tagaatacga cgtgattctt tatcgtagac
    20521 aatcttaatg gttacttgga agttaccatg ctcgataaat tctggttttt gattgtcagt
    20581 gtattctgtt actgctgcat caaagccaag gcattttgct ttctcaagag ttaagccagt
    20641 tgataccatg tgcaagccgt agatagagat accatttgat ccctgcacac caataccctc
    20701 aagagctgtg ccacaagcgt tatgagctgc gacaatccct gtacgaacag catttgaagc
    20761 aagggcaata taattggtat cgcgagttgc gttgtcatag atggttgcac aatcaccgat
    20821 tgcataaatc cctggaatag atgtttcttg gtgtttgtta acaaggaagg caccattacg
    20881 gaaaagctca atcttgccag caccaagagc tgtatttgga cggaagccaa ctgcaaggat
    20941 aaccatatca acatcatatt cattcttatc agtgattagc ttttcaacct tgccatcacc
    21001 agcaacctct ttgacagttt ccccaaaggc caactgaata ccatgctctt ctaggttttt
    21061 agacatgaca tctgtcaaat cacgatcata gtagcctgct agacaagtat ccgcaacatc
    21121 aatcagaata acctctttgc ccttacgttg gaaggcttct gcaagctcta caccaatgta
    21181 gcctgcacca acgactgcaa cgcgcttaat gtctttgttt tctaatttcg aaatgacatc
    21241 tgctgaattt tggtacaatt taacgaattg aagattttca agtgttgctt caaactctaa
    21301 tgagccctct ttgatttctg cacctttaat tggtggcaag ataggctgtg aaccagttgc
    21361 aaaaattaat ttgtcatatg actcaacatg ctctttgcca tcaacaaggg ctgtcactgt
    21421 tttagcatcg tagtcaatag attgaactgg tgattccatg taaaccttag caccaaggga
    21481 ctctagctct tccttatttg agtagaataa gccctctggg ccagaaattt gttcgccaat
    21541 ccaaagtgcc ataccacagc ctaagaatga aatatttgag ttttggtcaa atacaacaat
    21601 ctcattagca tcaccatagt ttgttaacat agtcttgata catgccgtac ctgcgtggtt
    21661 tgcaccgata acaacgattt tactcatatg attatgttcc tcatttcaca atttatatta
    21721 ggtctctatt ataacacagg gaaaaagcgc ttccaactaa aatgctcatt tttcttgctt
    21781 ttttataccg ttttttagtc aataaataag acagcctatc atttgttgaa gggtcgtaca
    21841 aagaccggtt tgcttcagtt aagtcaagac gacattctta ttcaactatt ttcccaaatt
    21901 cattacatga ttaagaccat tttttgtcgt taacttctaa aaaagactca taagctcaat
    21961 caggtaaaga ttgacatgta cctcttgagc ataataaata ttgccgccgt tgcaataaag
    22021 ctttccacca gagaggaggg ctaaggggtg gtaataaaaa taggtttttc cagtagtatt
    22081 tcctaggctg ggtgcaacga cagttctaga atagttagtg gctagttcaa ttgtatgctg
    22141 accgccattt ttagcaacgt aatcaatata ggcggttcca aaattgtaag cttgaacagc
    22201 tgtccaaggg tctacgccgg ctttttctgc taaagctaaa ttgtgagata gcaatctgac
    22261 accatactca atgctagatt gactatcggt gatcgaatcc cttatgccag agctgctttc
    22321 gcttgactgc ataacgtcag cttctcctcc cttagtttcc gtgtatatca tggctagtac
    22381 cagatcgacg tctgctttgt taccgttttc tgctaaaata cgctctactg ttggcttgta
    22441 ttgtaggact ctgtgcacat tcttatgaat ggtaactgct tcgtacaggc aaaaaatgag
    22501 gacggctaat cctaagatac gctttaacac tctaaacatt tagttatttt tgatatcctc
    22561 tatatttttt atcaatatgg aataggttcc gttgtcattc aagataaact ctactgactc
    22621 agcatcttga taaactgcat tagggacaag aagctcaatt ccatttgaca gcgacagctt
    22681 ttgcgtctct agctttttta gctgtctaga atgatcaata tcactgacct gaattggttc
    22741 gggaatcatt tccttgacct gatccacaaa ggttaacctt gcagtcaggt tctggtcaaa
    22801 taattgatct gctagctttt ctggagatag agctgtttct tcttctagat ttttagccag
    22861 tgctactttc atctttgatt gaaaagcaaa gtcatcttgg ttaaaattct cggcaacctt
    22921 ttgagcggtc tgctcaagca tttgaataga ttttttgaca gattgctcag gtgttacctt
    22981 tagcagcttc tcagaaaagt aatgagcaaa gcttccattg tgcttcatgc gtttttcgat
    23041 taagtagtaa tagcctgttt gacggttaat gaccaaggct tcatcaggtg cctgagtagg
    23101 gcttggcaaa ttattttgcg tgatcgtaat aggattttca tgatcgtctg atagatgggc
    23161 aaaatgctct tttagggcaa tgcgtaaaaa ggccagataa ggcactcctt ccttatcaaa
    23221 ctgaataaaa accaaatcgt ttgtcttttg atgttcagaa gcgacaaatt cttccttcca
    23281 aagcttggca attgttactg atgtttccaa aagctctgta ccgattgtgg taaaaaaagc
    23341 atgatcagct tctaattgcc cacgtttagc gtcgtcagaa aaaaccttgg ctaatttttt
    23401 gcgaaaatac tcatcaattc ttggtgttat agctactaaa gcatctgata agatcagctc
    23461 ggtatcgttt ggtgtgaatt ggtggatcac aattcctttt atataaatat ctagcattgt
    23521 tagttcttct tgtataatgg gaaggcgtca gtcaatcggc gaacctcata acggacctct
    23581 tcaaggattt caggctgctg gtggttaacc aaggccttga taattaaatg agcaatagtc
    23641 ctactttcgt ctactcccat tccacgactg gtaatggcag cgcagcctat gcgaatgcct
    23701 gatgttttaa agggagatag ggtctcaaaa ggaatagcat ttttgttaag ggtaatatta
    23761 acctcatcaa gcaaggcttg agcaagcttg ccattttcaa tcaccttagt cacatcaaca
    23821 aggaaaagat ggttatctgt accgcctgag atcagacgaa aacgatcatc cttggcaaaa
    23881 acctctgcca ttgctgctgt atttgctata acagcccttg catagtctgt aaaggcagga
    23941 tcaagcgcct ccttaaacgc aacagccttc gctgctatga catgctccaa aggcccaccc
    24001 tgtagaccag ggaaaatagc tgcattcatt ttccttgaaa ttgcttcatc atttgtcaaa
    24061 agcaggccac cacgaggacc acgaagggtt ttatgagtgg ttgaggtcac aatatgagca
    24121 taaggtactg gattttgatg cagacctgct gcaaccaagc ctgcaatgtg tgccatatcc
    24181 accatcaaat aggatcccac ctggtctgca ataaaacgaa attgctcaaa atcaatctgc
    24241 cgagaatagg ctgaggcacc tgcaacaatc aacttaggct gaacagcctt agcttgcttt
    24301 aggatagctg cgtagtccag cttttcagtt tccttatcga cagtgtagcc gacaaattga
    24361 taggtttttc cagaaaaatt gacaggtgag ccatgtgtca agtgacctcc agctgccaaa
    24421 tccataccaa gcacagtgtc accagcatta atcagtgcca tataagcagc agcattggcc
    24481 tgactaccag aatgaggctg aacgttggca taggctgcac caaagagctt tttggcacgc
    24541 tcaatagcaa ggctttcaac aatatcaaca tactctgtgc cgccataata acgcttgctt
    24601 ggatagccct cagcgtattt gttggtcaag acagagcctt gtgcttgcat aacagccttt
    24661 gagaccatat tttcagaagc aattagctca atattatgct cttgcctgtc ctcctcggcc
    24721 tgaatagcct cccaaagctc ctgatcatag tctttgtagt tctcgttgtt aaacatcatt
    24781 attgtctcct ctataatagc ttcataaatc gtaattgtgt cttatcatct acatagctca
    24841 gcttacggta aaaggcatgt gcctcggtcc tgtgactagc agaattaagc cgaataaagc
    24901 ttactttctc ctgcttagcc ttctcctcta aagcagctag taagcgacga ccgatacctc
    24961 taccttgatg gtccagcctc actgctaagg ccaaaatatt aaagcctttt tccgagtaaa
    25021 gcgactcgta gcattcagca tgcagatagc ctaagagcag attggtctta gtatcagcat
    25081 agcccagcaa ataatgatgc ttatcggatc ttagtttttc caattggctt tttgtcaatt
    25141 caagagaaac cttgtacccc aaggattgat cattaatgtc acaaatagct tgacaatctg
    25201 tttgatctag tggtcttagc atagccttac ctcctctaaa atggcagctc tggaacctta
    25261 gctaataatt gctccttagt aatagcacct tgtcgtaaaa tactgacctt aggtgacgat
    25321 aaatccaaaa tagtagaatc cttccctgtc aaataggcat catcagcata accatcaacc
    25381 tttccatcaa atgccttgac aatgtcatta aagcattttc cactctttga gcctgacagg
    25441 ttagcagatg gcccaatcaa gggacccgtt gctctgataa ttttagctgt gagagggtga
    25501 ctgggtagtc gaaagccaac tgtttttagc ccagaattaa tccaataggg tgtctgggca
    25561 ttggctttta ggataatcgt aagtggacca ggtaaaaaag cctcgtacag cttgttaaga
    25621 taggcaggct gctgcttaga aaaagccaaa atactctcaa aatcagccac attaaggttc
    25681 atagccttgt cgcgaggcct ttttttgaga cgataaacag cattaacagc ctcttcattt
    25741 aaggcctgag caaaaagacc ataaactgtc tcagttggta aaataagagc tccaccagcc
    25801 ttaattgtct ctatcaaatg tgttatcatc aacaaccacc attctttctt tacccagcat
    25861 atccttaagc actctgatac gcttttgagg gaaacgcttg gataagagcc tttttaagcc
    25921 ttctccctgc ttgtagccta tttcaaaata gagcttacca cttgtcgtca gataagcact
    25981 agcttgttcg ataatgcgtc ggtaaataga aaagccattt tctgcagcaa ataaggccaa
    26041 atgcggctca gattgataaa cattcaagcc aacctcgtcc ttatcctcat aggcaatata
    26101 gggagggtta gaaacaatga tgtcaaactg ccctgatagc ttgctaaaaa ggtctgactg
    26161 ctcaaaggct atctctacat gatgatctaa agcgtttgag taagcaaggc tcaaggcatc
    26221 agctgaaata tcagaggctg tgacctgcca gttaggtctt gcttttttta aagcaattgc
    26281 aatagcacca ctgcctgttc caatgtctaa aacggatttg cgagtagcgt cattttcctt
    26341 caagataagc tcaactaatt cttccgtctc tggtcttggg attagcacgc gcgaatccac
    26401 tgcaagcacc agatctctaa aataagccct gcctgtgata tattgtggcg atacatgctg
    26461 gctaagcgct aaaaaaatcc gctctaataa ggcttgatcc tctgaagtga cctcttgatt
    26521 ttgatgaagc aaaaagtcaa ggcttgtcca ctgctttaat tctttaaaaa cataggcgag
    26581 gttttcacga tcctcaccta tgttttctag cctgtcttcg taggctctta gttgcttagc
    26641 atagttcatt ggttatttag cgattctaat ttctgagttt gatcatatag cactaaagcg
    26701 tcaacaatct cgtctaactt tccagacaaa atggtgtcta atttttgcag ggttagaccg
    26761 atacggtgat ctgtcacacg attttgtggg aaattatagg tccgaatccg ttcagaacga
    26821 tcacccgtac cgatagttga tttacgctct gcgtcctgct cgtcctgtgc gatctgtgca
    26881 aaatgatctg ctacacgtgc ccgaataatc ttcatagcct tgtcacgatt cttttgctgc
    26941 gttctttcct cttgcatctc aaccttgatg tttgttggga gatggacgat acgaacagcg
    27001 gttgccacct tgttgacatt ttgtccgcca gcaccagaag catggtaaat atcaatacga
    27061 aggtcctttg gatcaatgtc gtactcaact tcttctacct ctggcatgac taagacagtc
    27121 gcagttgaag tatgcacgcg cccttggctt tctgttacag gaacacgctg tacgcgatga
    27181 gcacctgatt cgtattttag cttggaataa acagattgtc ctgaaaccat agcaacaacc
    27241 tctttaatcc ctccaacacc attataggaa gcctccatta cctcaaagcg ccagccttgg
    27301 ctttcggcaa atttttggta catggctaag agatcaccgg caaatagagc agcctcatca
    27361 ccacctgcgg caccacgaat ttccaagata atatttttat catcatttgg atctttggga
    27421 agcagcaaaa gctttaactt gtcctcatag gcttccttgg cagacttggc ctcttttagc
    27481 tcctccttgg ccatctcttc aatgtcagga tcgccgccgg cttccttaat catctcctca
    27541 gcgtcatcaa tggattggat aatagcctta tactgacgat aagctgctac tgtttctcgt
    27601 gtgctagcct cttcctttga cagagccata aaacgtttgg tgtcagaaac aacctccgga
    27661 tcacttaata attcgcctaa ttcttcataa cggtcctcaa cggcctgtaa ttgatcataa
    27721 atattcatta gggggtattc tctcctcttt ttacttgttt tagttgttat tagattggtg
    27781 ggtgaaaata atgcttgcga caaactggaa tataggtctc attgccacca atttgaatct
    27841 gtgctccctc ataaacgggc ttaccatgtt ctgttcgcaa taccatagtt gcttttttgc
    27901 tgcaatattg acagatggtt tttatctcat caatcttatc agctaacagt aacaggtatt
    27961 tggagccttc aaacaattca ttttgaaaat cattttttaa gccaaaggcc atcactggaa
    28021 catttagctc atcaaccaca cgtgctaaat catagacatt ttgcttgctt aaaaattgac
    28081 attcgtcaat caagacgcaa tagggcttct cctgcaattc agcaataaat gcaaaaatat
    28141 ccatatcatt cgaaattggt acagcctcac gacgcatgcc aatccgacta gaaacaatgc
    28201 caaagccatc acgtgtgtct agcgcacttg tcataatcac aacaggcttc ccctgttctt
    28261 cataattgtg tgctaccttc aagatttcaa tggtctttcc tgaattcatt gttccatatt
    28321 tgtaatataa ttgagccaaa atggagattc ctaccttctt cttttgtcct acttattcta
    28381 tcatatttgt ccctatttgg cgattgcctt atctgaaaat cttattttca caacagctaa
    28441 atcctgtgct gttgagctaa ggttaggctt tttgaagctg acatgctaca atagaggtat
    28501 cattaaaaaa aggagattga ctattatgcc atttgtaacg attgacctgt ttgaggggcg
    28561 tagccaagaa caaaaaattg ccctagcgcg tgaggtgaca gaggttgttt ctcgtatcgc
    28621 acaggctcca aaagaagcga ttcatgttgt aatcaatgac atgcctgagg ggacctattt
    28681 cccgcatggt gagatgaaaa ccaaagccta atgcctaagt cccacttatc taggtgggct
    28741 tttcctattt gaaaaggagg gcctgatgat agctactgat cagatcaaga tgatgggaac
    28801 aatcattgat atttgcattg actcatcaaa agcaaagcag caagcagcta ctatccgaga
    28861 gctactaacc ctttacaatc accgtttttc ggccagtgac gacagctctg aattaatggc
    28921 aatcaaccat atggcaggta ttcagccagt gcgtgtgcat tcagatttgt ttgacttaat
    28981 ctcaatcgga aaagagcata gcttggctta tccaagcaac cttaatatca cacttggtcc
    29041 tttagtgcaa agctggcgca tcggcttttc agacgctaag cttccagatg aagcaactat
    29101 tgatcgcaga ctaagactaa ccaatcctaa tcatatcatc
//
LOCUS       DARYXZ010000029        28088 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYXZ010000029 DARYXZ010000000
VERSION     DARYXZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28088
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..547)
                     /locus_tag="TV186_001150"
     CDS             complement(<1..547)
                     /locus_tag="TV186_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1532548.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGE"
     gene            889..1572
                     /locus_tag="TV186_001151"
     CDS             889..1572
                     /locus_tag="TV186_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1532549.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            1574..2311
                     /locus_tag="TV186_001152"
     CDS             1574..2311
                     /locus_tag="TV186_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1532550.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            2755..4449
                     /locus_tag="TV186_001153"
     CDS             2755..4449
                     /locus_tag="TV186_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1532551.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            4561..5415
                     /locus_tag="TV186_001154"
     CDS             4561..5415
                     /locus_tag="TV186_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL1532552.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            5412..6266
                     /locus_tag="TV186_001155"
     CDS             5412..6266
                     /locus_tag="TV186_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL1532553.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            6550..7890
                     /locus_tag="TV186_001156"
     CDS             6550..7890
                     /locus_tag="TV186_001156"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL1532554.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            7868..8083
                     /locus_tag="TV186_001157"
     CDS             7868..8083
                     /locus_tag="TV186_001157"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL1532555.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            8083..8952
                     /locus_tag="TV186_001158"
     CDS             8083..8952
                     /locus_tag="TV186_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL1532556.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            8945..9772
                     /locus_tag="TV186_001159"
     CDS             8945..9772
                     /locus_tag="TV186_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL1532557.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            9759..10229
                     /locus_tag="TV186_001160"
     CDS             9759..10229
                     /locus_tag="TV186_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1532558.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            10247..11908
                     /gene="recN"
                     /locus_tag="TV186_001161"
     CDS             10247..11908
                     /gene="recN"
                     /locus_tag="TV186_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL1532559.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVIAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            12129..13001
                     /locus_tag="TV186_001162"
     CDS             12129..13001
                     /locus_tag="TV186_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1532560.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            13139..13990
                     /locus_tag="TV186_001163"
     CDS             13139..13990
                     /locus_tag="TV186_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1532561.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            13983..14825
                     /locus_tag="TV186_001164"
     CDS             13983..14825
                     /locus_tag="TV186_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL1532562.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            14803..15390
                     /locus_tag="TV186_001165"
     CDS             14803..15390
                     /locus_tag="TV186_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL1532563.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            15488..15763
                     /locus_tag="TV186_001166"
     CDS             15488..15763
                     /locus_tag="TV186_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL1532564.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(15824..16528)
                     /locus_tag="TV186_001167"
     CDS             complement(15824..16528)
                     /locus_tag="TV186_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL1532565.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(16839..18047)
                     /locus_tag="TV186_001168"
     CDS             complement(16839..18047)
                     /locus_tag="TV186_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1532566.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(18102..18995)
                     /locus_tag="TV186_001169"
     CDS             complement(18102..18995)
                     /locus_tag="TV186_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1532567.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            19364..19537
                     /locus_tag="TV186_001170"
     CDS             19364..19537
                     /locus_tag="TV186_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532568.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(19582..20517)
                     /locus_tag="TV186_001171"
     CDS             complement(19582..20517)
                     /locus_tag="TV186_001171"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL1532569.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            20760..21455
                     /locus_tag="TV186_001172"
     CDS             20760..21455
                     /locus_tag="TV186_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1532570.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            21564..22085
                     /locus_tag="TV186_001173"
     CDS             21564..22085
                     /locus_tag="TV186_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL1532571.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            22480..23019
                     /locus_tag="TV186_001174"
     CDS             22480..23019
                     /locus_tag="TV186_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532572.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            23158..23928
                     /locus_tag="TV186_001175"
     CDS             23158..23928
                     /locus_tag="TV186_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL1532573.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            24040..26094
                     /locus_tag="TV186_001176"
     CDS             24040..26094
                     /locus_tag="TV186_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL1532574.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            26106..26702
                     /gene="recR"
                     /locus_tag="TV186_001177"
     CDS             26106..26702
                     /gene="recR"
                     /locus_tag="TV186_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL1532575.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            26850..27896
                     /locus_tag="TV186_001178"
     CDS             26850..27896
                     /locus_tag="TV186_001178"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL1532576.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT         7737 a         5190 c         6929 g         8232 t
ORIGIN      
        1 tttcaccgcg ttgtccttgc tcgccttttt caccgcgttg tccttgctca cctttttcac
       61 cgcgttgtcc ttgctcacct ttttcaccgc gttgtccttg ctcgcctttt tcgccgcgtt
      121 gtccttgctc acctttttcg ccgcgttcgc ctctgtcacc cttagggccg gctggtcctt
      181 gttcaccttt aggacctgtt tctccggttt cgcctttatc tccacgtggt cccataggcc
      241 caacaggacc ttgctctccg cgttcccctc taggtccggc aggccccaca ggtccctgag
      301 gaccaccttt tttagcttgt agttctaagt tttgtaagta ggtttgcatg aattgtctta
      361 atgtatgtag gtatactctt acttcgccat ctccgagtcc gtccctaatt agttcagctg
      421 gatctggata ggactctaat cgcgtataat cttcagctcg ggcatttcca gctgttccta
      481 ggctggccat tgttgctagg gcaatggctg ctgagcagac gctgtacttg cgtattgttt
      541 ttttcatctt tctctccttt gatgatagta tcattacttt ttcaaaattc tttcccgaag
      601 aagagtttaa catggtagct tgctatgaga aacagctagg cgccactttg tctccgtagt
      661 ttttttaatt caatgctgaa tcgtctgatt ttatcagagg gttattgttt ttaaaggcga
      721 ggagttgctt tgctcagcta gtctagcaag ttcacaggtc agcttatgtt tcttatcaag
      781 cttgtttgtt tttgagaata tttttcgata aaaagatgtt gtattaatat tcatgttata
      841 gtataattat attcgttgcc atgactttat gaatgttagg agataggaat ggattttacc
      901 tttttaccca aatactgggc ttatttcaat tatggtgtgc ttgtaaccat gatgatttca
      961 gcctgtgttg tcttttttgg cacgattata ggtcttttag tgaccctgat aaaacgcagt
     1021 catatcaagc ctttgtcttg gcttgtcagt ctttatgtct ggatttttcg tggaacgccg
     1081 atggtggtac agatcatgat tgcttttgct tggctgcatt tcaacgatct gcccattgta
     1141 ggctttggtg tgttggattt ggatttttca agactgcttc ctggtattat tattatttcc
     1201 ttgaatagcg gtgcttacat atctgaaatc gtcagggctg ggattgaggc ggtgccaaag
     1261 gggcagctgg aggctgctta ctctcttggt atccgtccta agaacgccat gcgctatgtg
     1321 attttgcctc aggcctttaa gaatattttg ccggccttgg gcaatgaatt gatcaccatt
     1381 atcaaggata gtgccttgct tcagacgatt ggtgtgatgg agctttggaa tggagctcag
     1441 tcggttgtga cggcgaccta tctgcctatt acacccttgc tgtttgcggc cttttattac
     1501 ttgatgataa caacaatatt gtcgcaatta ttaggctgct tggagcgcaa gctagcacag
     1561 ggagggagat aagatgactg agacagtgat ttcgattcgt cagttgcata agagctttgg
     1621 caagcatgag gtgctaaaag gaatagacct gaccattaat cagggtgagg ttgtggtgat
     1681 tattgggcca tctggctcag gaaagtccac gctattgcgc acgatgaatt tgcttgaggt
     1741 gccaacaaag ggacacatca gctttgaggg cgtcgatatt acggataagg caaatgatat
     1801 tttcaagatg cgtgagaaga tgggcatggt ttttcagcag tttaatctgt ttcccaatat
     1861 gacagtgctg gaaaacatca ccctgtcacc catcaaaaca aaaggaatgt caagggctgg
     1921 cgcggagcag agagcttatg agctgcttga gcgagttggg ctgagagata aggctgctgc
     1981 ctatccggca agcttatccg gtggtcagca gcagcgcatt gcgattgcgc gcggcttggc
     2041 aatggatccc gatgtgctgc tctttgatga gccgacctca gcgcttgacc ctgagatggt
     2101 gggtgaggtt ttggctgtta tgcaggattt ggcaaaatca ggcatgacga tggttattgt
     2161 aacgcatgaa atgggctttg ccaaagaggt ggcggatcgc gtgattttta tggacggtgg
     2221 tcttgtgatt gaagagggca gtccagttca ggtatttgaa gctcctaagg aggagcggac
     2281 caaggacttt ttgagcaagg tattgtcata gctggcgcag ctaaagggca gcatgtcacc
     2341 tcaaggtctg gctattagtc aattggctgt ttgttttggg cattttgttt gtaaaaggct
     2401 tagaaagtct ggttggtgct gtagccatat ctggctttgc tacgcttggg ctgctagctg
     2461 gtcagtgggt atcatagtga ttggaggtgt ggtctcttta ttggtcaaca ttgctgtggc
     2521 aggctagcac aggggctttg cttgttgtgc tgggtaaggg gtttcatttg catgactgtt
     2581 aacattgctt aattgatgaa ttaggttgac ttttgtttta ttgtttgata ctattcaggt
     2641 aagtctgtca ttagaaagcg ctttgctttt ttgatgatgg aaatcatgat catatgatca
     2701 cgtcttaggt aatatgttgt tgtcaacatg gtggtctgaa agtaggagga taatatggac
     2761 tacaaagctg tttatcagga gtggctgcac aatgattttt tcaatgaaga aatcaaggca
     2821 gatttagagg cgattaagca tgatgaggct gagattcaag accgttttta taaggtgctt
     2881 gagtttggga cagcaggact tagaggaaag ctcggtgctg ggaccaaccg tatgaatatt
     2941 tacatggttg gtaaggctgc gcaggcttta gctaatacca ttattgatca tgggccagag
     3001 gcagtctcac gcgggattgc catcagctat gatgtgcgct ataagtctaa ggaattcgca
     3061 gaattgacct gctcgatcat ggcagccaat gggatcaagt cttatatcta caaggggatt
     3121 cgtccgacac cgatgtgctc ttatgcgatt cgtgccttga actgtatctc tggtgtcatg
     3181 attactgcta gtcacaatcc tcaggcctac aatggctaca aggcttattg ggaagagggg
     3241 tcacagatcc tagatgacat tgctaatcag atagcggttc atatggacgc tattgagcgc
     3301 tttgaggacg ttaagcagat accctttgag gaggcattgg caagtggtct gaccagctat
     3361 attgatgata gtatagagga ggcctataag aaagaggttt taggcttgac catcaatgat
     3421 actgatattg ataagtcagt gcgtgtggtt tatacacctt tgaatggcgt tggtaatttg
     3481 cctgttcgtg aggtattgaa gagacgaggc tttgatcatg tctttgtagt gccggagcag
     3541 gaaatgccag acccagattt cacaacagtt ggttatccaa atccagaggt accaaaggcc
     3601 tttgcttatt cagaaagact agggcaagaa gtaggagcag ctattctgat tgcgactgat
     3661 ccggactgtg atcgtgtggc actagaggtt cgagctgctg acggtagtta tgtctttctt
     3721 aatggtaata agattggtgc tttgttgtcc tactatatct tttcacagcg tcatgctagg
     3781 cataatcttc ctgacaatcc tgtccttgtc aaatcaattg taacagggga tttatcaaaa
     3841 gctattgccg ctaaatatga cgttgaaacg gttgagactc ttacaggctt taaaaacatc
     3901 tgtggtaagg ctaatgacta tgacatcaca aaggagaaga cctacgtctt tggctatgag
     3961 gaaagcattg gtttttgtta cggtaccttt gtgcgtgata aggacgcggt tagcgcctca
     4021 atgatggtgg tagaaatggc tgcctactac aagcaaaggg gtcagtcact cttagatgtg
     4081 cttcaagaca tttacaagga atttggctat tacaatgagc gtcaggtagc gctagagcta
     4141 gagggtgttg aggggcagaa gcgtattgca cgtatcatgg aggactttag aaatgagcct
     4201 attgagcatg caggtgctat gagcttgaag accattgtag actttaagga cggctacctt
     4261 gattttccaa agcaaaattg tttgaaatat tattttgatg atgggtcatg gtatgcgctg
     4321 agaccatctg gaacagagcc taagatcaag ctttacatct atactattgg tgaaacagag
     4381 gcagacagca ttgctaagct agacgctatt gagtcagctt gtcaagcaaa gatggacagt
     4441 gtcagctaat tgttcaagct ctgcaacaga aaatcagcta atcaataagc aaaaaggaaa
     4501 aggaagtgac agtgcttcct tttttcgtta taatagttaa aaaattagca aggagtgcat
     4561 atggtacaga ttattgatgg gaaggcccta gcacagaaaa tgcaggcagc attggctaag
     4621 aaggtagaga gcttaaaggc agaaaaagga attgttccag gccttgttgt cattctggta
     4681 ggagacaacc ctgctagtca ggtttacgtc cgtaataagg aacgcgctgc cttagcagca
     4741 ggctttaaaa gtgaaaccgt tcgcttgtct gattcagtct gtcaggaaga gttgatagag
     4801 ctcattgagc aatataatca agatgatacg attcatggta ttttagtgca gcttcctctt
     4861 ccgcaccata ttaatgacaa aagcattatc cttgctattg atcctaaaaa ggacgtcgat
     4921 ggctttcacc ctatgaatac aggtcatctg tggtcaggtc gtccgaatat ggtcccttgt
     4981 actccggcag ggattatgga gatgtttcat gactatggta tcgaacttga agggaaaaat
     5041 gctgttattg tcgggcgctc aaatattgtt gggaagccta tggcgcagct actgttggat
     5101 aaaaatgcta cggtaacgct tacccattcg cgcacgcgcc gactggcaga tatttgtcgt
     5161 cgtgctgata tcttgattgt tgctattggt caggggcatt ttatcacaaa ggagtttgtt
     5221 aaagagggtg ctgttgttat agatgttggt atgaatcgtg acgtcaatgg gcgattgatt
     5281 ggagacgtcg cctttgatga ggtgtcagag ctggctagca tgattactcc tgttccgggt
     5341 ggtgttggac cgatgaccat tactatgctt ttggagcaaa cctatcaagc agctctaaga
     5401 agggtgagtc aatgattata gatcaatcgt ttgttgctag ggttgttgtt ccgcggcagg
     5461 ctgactccca taaggggagt tacggcagag tactgttagt aggtggcttg tatccatacg
     5521 gtggtgctat tattatggta gcgctggcct gtgttcatag tggtgctggc ctagtaactg
     5581 ttgcaactga tagagaaact attgctgcct tgcatagtca tttgccagag gcgatggcta
     5641 ttgcggtaga tgatgaggaa ttactgttat ctcagctagg tatggcagac ctgattttga
     5701 ttggtccggg gctgtcggag aatagcagag cagctaggct gtttgaattg gtccttgcac
     5761 atgtcgctga tcatcaggta ttggtcattg atggctctgc cttaaggctt ttagcgaaaa
     5821 gggcagctga tgttaagcag ctgaggtgcc ctcttgtgtt aacgccacac caaaaggaat
     5881 gggaggcgct gtcaggttta gcgattgatc agcagtatga tgctgccaac caagcagctc
     5941 tcaagcattt tccaagggct acgattttgg ttgctaaaag ctcagcaacc aagatttatc
     6001 atggcaacca gatctaccgg ctaagagtgg gcggacctta tcaggctaca ggtggtatgg
     6061 gggatacctt ggcaggtatg atagcaggaa tagctgtcca gtttccagag tcaagcttgg
     6121 tggctaaggt tgcttgtgcg acctatctgc actctgcgat tgctgatgag ctggcaaaga
     6181 ctgcctatgt ggttttgccg actgctatta gctatgagct tcctagatgg ctaaaggcaa
     6241 tcagcacagg ccagaagcta ggttgaggct gtgctgcgag gtcgtttggg aaaagcggtt
     6301 aattggtagg catgacagca gctggtttca gtcgtttagc tattttgagt ttagagctgc
     6361 tagcttaaga ctgggtgctg ctttatgatt caaggaagct atcattggaa aaacttgtgt
     6421 caagctgtag aagccctagc tggcttcttt ttttgtctct tttttgctca ctatttatgt
     6481 ggaaacatga tataattgca ttagtataca gttggagcag ttaggcttca tgaagtgaaa
     6541 ggtaaactga tggcagacta tttatccgtc actcagctga caaaatattt aaaattgaaa
     6601 tttgatcgag acccttatct ggagcgtgtc tatctcactg gtcaggtatc taatttcaga
     6661 aaaagaccaa atcaccaata tttttcctta aaggacgagg gagcggtgat tcaggccacc
     6721 atgtgggcag gagcttataa aaagcttggc tttgatttag aagagggcat gaagctcaat
     6781 gtggttgggc gtattcagct ctatgagcca aatggctcgt attcaatgat cattgaaaag
     6841 gctgagccag acggtattgg tgctttggcg ctgcaatttg agcagctcag gcaaaagctg
     6901 gctggtgaag gcttctttga tgagaggcat aagcaggccc tgccgcaatt tgtgacaaag
     6961 gtaggtattg tgacgagtcc aagtggggct gtgattcgtg atattatcac aaccatctca
     7021 aggcgttttc ctggggtgag tattcttttg tttccaacaa aggttcaggg tgagggggca
     7081 gctcaagagg ttgctgctaa tattactaag gctaaccagc gtgaggatct ggatttgttg
     7141 attgttggac gcggcggtgg ctcgattgag gacctgtggg ctttcaatga ggaaatcgtt
     7201 gttcaggcta tttttgagtc tcgcctgcct gttatttcca gcgtaggaca tgagacagat
     7261 acaaccttgg ctgattttgt ggctgatcgc agagctgcca ccccaaccgc agctgcagag
     7321 ctggcgacac ctattacaaa aacagatatt gtctcttgga ttgctgagca gcagagccgg
     7381 tcctatcaag cctgtctgcg ctatatcaga caagggcagg agcgggtgga taagctttct
     7441 tattctgtta ttttcaggca gccagagagg ctctatgatg cttatagtca acgcttagat
     7501 aggcttacga cctccttgat gaccactttt aaagagacat tatcaggagc taagcaggag
     7561 cacttgattt tggagcatcg tttagcctct gtcaatgtac aggcaaggct tgagcgttat
     7621 caggatcgtc tggcaactgc gcatcgtctc ttgatagcca atatgaccaa tcaatatgac
     7681 agtaagctag caggctttga gcgagctcaa gctgccttgc tgtcgcttga tacgagccgt
     7741 atcattgccc gcggctatgc cctgttaaaa aaggacggtg tagtagctgc ttgtgttaag
     7801 gacattaaaa agggagatca tcttagtatt atcatgcgtg atggtcaatt agaagtagag
     7861 gtagaagatg tcaacgaaaa aaatatttga agagcgttta caagaattag aggctattgt
     7921 gacgaggcta gaaaatggtg atgtgccact agaagaggcc atctctgaat ttcaaaaggg
     7981 tatggtgctg tccaaggacc ttcaaaaaac cttacaagca gctgaaaaga cacttgttaa
     8041 ggtcatgcag gcagatggca cagagctaga aatggatgcc taatggataa gctaacaaga
     8101 attaatgcca cgattcatca gtattatgac aggcagtcta ctgtttcagc agatctggag
     8161 gaggccattt tatattctgt tgatggtgga ggaaagaggc tccgtccact catgttattg
     8221 gagctgctag agggctttgg tcttgccttg acagacgctc attacgcggt tgctgctgct
     8281 gttgagatga ttcatacagg aagtttgatt cacgatgatt tgcctgctat ggataacgat
     8341 gattaccgtc gcgggcgact aactagccac aagcaattta atgaagcaac tgctattttg
     8401 gcaggagata gtcttttttt ggaccctttt gctctaatcg caggggcaga tttgccggct
     8461 gacctgctgg tgcaattgat tcagcagttt tccttagcgt caggaacctt tggcatggtc
     8521 ggtggtcagc tcttggacat gaagggtgag catcagctgc tggatattca ggagctatct
     8581 gatattcatg ccaataaaac agggaaattg ttgacccttc cttttgtggc tgcgggtatc
     8641 atagctgagc agtcagcaga cgttttgtct tgtctgtggg aggctggtag gcttgttgga
     8701 caggcctttc agataagaga tgatatatta gaccttacgg ctagctttgc tgatcttggc
     8761 aagacaccgc aaaaggacct tgctgctgca aaatcaacct atccgagtct gcttggttta
     8821 gagcgctcaa gggctatttt ggaggagtct ttgagtcaag cgctagctat ttttagcaga
     8881 ctagaaaggg aagaaggctt tgagtctcag gctattatca aaaggatcga ggggttgcga
     8941 ctaaatggct aaagaaagag tagatgtgct agcctataga cagggacttt ttgaaacgcg
     9001 agaacaggcc aagcgcggtg tgatggctgg gctagttata tcagctataa gtggcttacg
     9061 ctttgataag cctggtgaaa agattgatga ggggatcgaa ctaaggctca agggtgagaa
     9121 gcttaagtat gtcagccgag ggggtctcaa gctggaaaaa gccttgcagg tctttgggat
     9181 ctctgtgcag gataaggtga caattgatat tggtgcttca acaggtggct ttacagatgt
     9241 tatgctacag gcaggagcta ggctggttta cgctgttgat gttggaacca atcaattggt
     9301 ctggaagctc aggcaggata gtcgtgttcg aagcatggag cagtacaatt ttcgctatgc
     9361 aaagctagca gatttttcag aaggtcagcc agcctttgcc agcattgatg tgtcctttat
     9421 ttctcttagc ctgatactgc cgacattgca ctgtattttg caggaagggg cagaggctgt
     9481 tgctctgatc aagccacagt ttgaagcagg gcgcgagcag attggcaaaa aagggattgt
     9541 caaggataga ctgattcatg aaaaagtgat taagcaggtg gcagatactg ctcttaattg
     9601 cggatttatc gttaaggggc ttgatttttc gcctatccaa ggtggtcatg gcaatattga
     9661 atttttggct catttagtca agggaaaggg ctccaaggct attgatgatc agctcataca
     9721 gagcgttgtt agcagtgcac ataaggaatt taaacagcat gaaaaagagt gaacgattag
     9781 atttaataaa aaaaatggtt ttgtctcatg agattgagac tcagcatgag ctattaaagc
     9841 tcctagctga ttatgggcta gagctaactc aggccactat ttcaagagac atgaatgaaa
     9901 ttggcattgt caaaattcca tctggaactg ggcgttatgt ctatggcttg tcacaggata
     9961 gtggcaagcg ggtggtgcaa aggcctgcct ctatcaaaaa aacgattttg gaaatgtctg
    10021 aaaaaacagc gggcttggag cagcatattc acctcaacgt tgttccaggc aatagcaagc
    10081 taatcaaacg ttatttgatg acagactttt caggtcaatt gtttagcctg attgcagatg
    10141 atgatagttt gctgttgatt gcaaaatcag aagcagacgc tgatcatatc cgtcaggaat
    10201 tgtccctttg gatgcaggga ttggtctaaa aaatagagag aagccgatgt tattagaaat
    10261 ttccattaag aattttgcta tcatagagga aatctcttta aactttgaaa acggtatgac
    10321 cgtactgact ggggagacag gggcaggaaa gtccattatc attgatgcga tgaacatgct
    10381 gctgggtgcg cgcgcaagca ctgaggtgat tcgacatggt gctgataagg cagagattga
    10441 gggcttcttt tcggttgatg ctaatcctca tttagccgct gtgctggcag aatcagggat
    10501 tagcatggaa gaggagttga ttcttcgtcg tgatattttt gctaacggtc gtagcgtcag
    10561 ccgtatcaat ggtcaaatgg tcactgtcag caccctaaaa aaacttgggc agtttttagt
    10621 ggatattcat ggtcagcatg atcaggagga attgatgcgt ccacagctgc accagcatat
    10681 tttggatagt tttggagatg aggcctttga ccagctcaag cagtcctatc agcagatttt
    10741 tgatcgctat aaggctttgc gaaggcaggc tcttgagaag caaaaaaatg aaaaagaaca
    10801 tcaggcgcgc cttgacctgc tggcctttca gataggggaa attgaggcag cagatttggt
    10861 tagaggagaa gatgacctgc ttaaccaaga aaggcagcga ttgctcaatc acaaaaagat
    10921 tgctgatacc ttaaccagtg cctacctttc cttggataat gaggactttt ccagtctctc
    10981 acaggtccgc tctagcatga atgagttgct gtctattgag gaccttgccc cagagtatca
    11041 gcttatatca gctggtgtgt cagaggctta ttatattctt gaggaggtca caaagcaatt
    11101 atctgatacc atcgaccagc ttgattttga tgcaggcaga ttgcaggaca ttgagctgcg
    11161 tttagacagc attaatagtc tgacaagaaa atatggcggt ggtgtgaatg atgttttgga
    11221 ctactatgcc aatattacca aggaatacca gttattaagc ggagatgacc gttcctctga
    11281 tgagctagaa agggaattaa aggtccttga gaagcaactg gtgatgactg cctcacagct
    11341 aagtgacaag cgtcatgccc tggctctaga gctagaagcc gacatcaaag ctgagctgag
    11401 agagctttat atggaaaagg cggactttaa ggtccacttt acaaggtcaa agtttaatcg
    11461 agaaggcaat gaaagcttag aattttatat ctcaaccaat ccaggtgagg gctttaagcc
    11521 gctggttaag gttgcttcag gtggtgagct ttcccgcttg atgcttgcta tcaaggctgc
    11581 catttctaaa aaagaggaca agacgagtat tgtctttgac gaggtggata ctggagtttc
    11641 aggacgtgtg gcccaggcca ttgctaaaaa aatatataaa attggcagct atggtcaggt
    11701 attagcgatt tcgcatttgc cacaggtgat tgctattgca gataaccagt attttatttc
    11761 caaggaaagc aaggaggagt cgacagtgtc taaggctaag ctgttgacac aggaggagcg
    11821 gatcgaggag attgcgaaga tgattgcagg agctgatgtc acagagacag caagaaatca
    11881 agcgcgtgaa ttgctaggta aggactgagt atcatagcaa aagcagaaca gtagctttag
    11941 agcaagcttg cctgctgcac ttgtcgctac atgttcagaa tgagccacct gaaaggcaag
    12001 caagaaggct agctcttatg cgtatgctat cagaagctaa gtctttttgt ctcttgcatt
    12061 ggcgagtgat tgattgataa tattatgata aatagaagga ctaaaagaat actgactgag
    12121 gaggtaaaat gctgaaaaaa agaatgggct tggctagtct gctagtgttg atgacctttg
    12181 tgtatcagtg ctgttcagtt actgctgagc agtattccga tactgaggtt gaggtgctgc
    12241 agattagcga ggagaaaagc cagatcatgg aaaatcaaga ggcgcttaaa gacctcacca
    12301 cgtcgtctga tcagctaaag aaggaagctt taaagcctaa agaggcagct accaacaaga
    12361 gcaagcaaga ggcttcgaca gtttatttag ctgaggacga tcctgtaacc attgatagct
    12421 ctgacgagga aagcaatcaa gatatcatag cggattctgt tcctgatttg gttattaaag
    12481 gtgatcaggt ggatgtatct gaggttatgg tctctgtaaa ggaggattca tcgaaagttg
    12541 ctaagcaaag aactgacgca gcgcagcggt acagtatagc caagcatcaa ttgacccaaa
    12601 agcttgaggc ctttaatgcg gcaacggacc aattgctgac catgattgct aaaaaatctg
    12661 atttgactgg tcagtattat gtggttgggc attcgttggg agaaatgctg gctgctcaaa
    12721 atgagaaaaa gcttgctgag caattagtca tgcaacaaaa gcacaaaaaa ggcttaggct
    12781 catcagtcac tattttagac gaattaggac gtgtgatttc tgacattagt ggtcataaag
    12841 gcatgcttcc ttttaatcgt aagatcagct ttaaggtaca tcaagtcaga tacgatcttc
    12901 cactaactgg tgatcgaaca gtgctacctg cccagctggc tggcttactg cttttactaa
    12961 taggtcttat gctgcctaaa gtagctaaca agaaaagcta agatatggtc ttggcttttt
    13021 tatcttttaa gagggtgagt ttttgacaga tgttttagct aacaccaaga gctagatacc
    13081 agctttgctt tatttttaaa ggagtgataa aataaagaga cgataaatga ggttagaaat
    13141 ggaacttaag atgggaacta ttaaaattgt tgcagattca tcaatgacga ttgaaccaga
    13201 gctaatcaaa tctcttgata ttacggttgt accgctttct gtcatgattg atagcaagct
    13261 gtattctgat aatgagctaa aagaggaagg gcaatttcta cagctgatga gagctagtaa
    13321 gtcattgcca aaaactagtc agccaccggt agggcttttt gcagatattt atgagcgatt
    13381 ggtcaaggag ggggcgacag ctattgttgc cattcacctc tcaccagctc tttcaggaac
    13441 aattgaggca tcacgtcagg gagctgaaat tgcagcagca ccagttacgg tattggactc
    13501 aggctttaca gatcaggctt tgaagtttca ggtggttgaa gcggctagac tggctcaagc
    13561 tggcgctagc cttgaggaaa tccttgaggc ggtagaggat attaaacgaa agacagagct
    13621 ttatataggg gtatcagcac ttgagcactt ggttaagggg ggacgaatcg gtcgtgtgac
    13681 aggcttgctt agctccttgc tgaatattcg tgtggtcatg gaaatgaaaa atgataccct
    13741 gcaaacactt gttaaaggac gcggcaataa gacctttact aaatggctgg atagctatct
    13801 agcagaaaat agccagcgac agatagctga ggtggccatt tcctatgctg gtcagaggga
    13861 ttttgctgat agcctgaaga agacaatcgc tacggtcttt gatgggccaa ttactgtttt
    13921 ggagactggc tcaatcattc aaacacatac tggcgagggc gcttttgcgg tgatggttag
    13981 atatgaataa gcgagggttt ttgggaggcc ttatcttctt tttcagtgtt tttgccttat
    14041 catttgtgat attagctgtc cttattccaa agtctgaccc acagctgaag aaaagtgatt
    14101 ttctaaaaaa taagaagata agcctcaatt atattgctat tggagactcc ttgacagagg
    14161 gagtgggtga tctcaccaac caaggaggct ttgtgccctt attgtctggt gatcttggag
    14221 actactttaa tgctaccgtt aatactgaaa attacggtgt ttccggtaat accagccagc
    14281 aaattttaac gagaatgact gagaacaagg agatcacaga gcagctcaaa aaagctaatc
    14341 tcatgacatt aacggttggt ggcaatgatg tcttggctgt tattcgcaag aacttagcta
    14401 atcttaaggt atcaagcttt aaaaagccag caaggcaata ccaagagcgc ttacgcaaaa
    14461 tccttgattt ggccagaaag gataatcagg atctgccgat ctttgtttta ggtatctaca
    14521 atccttttta tttgaatttt caggagctaa cagaaatgca gacggtcatt aatgactgga
    14581 acaaaaaaac acaagaggtt gttgatgact atgaccatgt ttactttgtt ccaattaatg
    14641 atctattgta caaaggagta gatggtaaag agggcattgt ccagtcaaca ggagagcaaa
    14701 caacgattgt gaatgatgct ttgttttcag gggatcattt tcaccccaat aacacaggct
    14761 accaaatcat gtcagacgca gtaatggaga caataagaaa gaatggaaaa gaaattaaac
    14821 cttaattggt ggaaatgggc ttttttgcta ttattggctt ttaatgcagc ctttttagca
    14881 gttattggaa gtcgtattat acaaataaga gagcctaagt ctgagctgat caatcaaaaa
    14941 gcagcaaaga atattaaaat agggacctta acaaccacta aagagcaatt aaatgaggca
    15001 gtcgttagct acctaaagga ttttcagacg gaaaaaatga cctataaggt gtatgccacc
    15061 tcctcgacca ttctctttga aggaacctat cagctcttag gatatgaggt gccgttatac
    15121 atttattttc agcctcatcg cttaaccaat ggtgcgatac agctgcaggt tctctccttt
    15181 tctgtgggga ccctttcttt gccggaaaag gacgttttgc aatacttgaa atccagctat
    15241 aagctgccaa aattcgttga agtcttacct aagcaatcgg ctattattat caatctacag
    15301 caattggaaa atgatgccaa catctattta aaggctcaaa agattgatct tgtcaaggat
    15361 gatattcgat ttgacatcta taagaaatga gtctaactaa cgtttaatac ttgacctgtg
    15421 gctgtttttt agatatgata atatctgtta aagcgttaag cttactaatt atttggagga
    15481 ttgttaaatg gctaacaaac aagatttaat cgcaaaggtt gcagaagcaa ctgagcttac
    15541 aaagaaagat tcagcagcag cagttgacgc tgtcttttct gcaatcgaag cttttcttgc
    15601 tgaaggtgaa aaggtacaat taattggttt tggtaacttt gaggttcgtg aacgcgctgc
    15661 tcgtaaaggt cgcaacccac aaactggtga agaaattgaa attgcagctt caaaggttcc
    15721 agcattcaag gctggtaaag ctcttaagga cgctgtaaaa taataaatca aaaaaagccc
    15781 tatctcatta agctgtttag cctgtgagat agggcttttt ccattaagga aggagtcttg
    15841 tttcaataag taatcttgtg tgatcgtctg aaagattagc gccaataatt tctaatgtgc
    15901 actgtcttgg gaacaagagt tccatttcat aaggataaaa tgagtagggc tgtacaaaag
    15961 cagcctggct gccttgaggg acctgaattc ttaattccac tgagcgatgt ggcatagcag
    16021 catttttgat ggctgtagta ctcataaagc cttgctttgt ataatgagtg cctggcttga
    16081 tcgctgatag gatctgcgga tcaaaggtct tatcatggta gtaacgagcg agttcctctt
    16141 cagaagtgcc caattctgtt aagaatgttt cataaacata gcgatagacg atgatattcc
    16201 aagggatggt tagcttatga gtagcactat caagtaaggc tacagactgc tgcagctggg
    16261 catccaactg gctggtatct cccatcacct gttctagggc taggttaata gggctggcag
    16321 aggcgtatgt atactgatac atcatctttt tttctgcttc tgtaaaggct gtttgagacc
    16381 tccagcgatt ggtgataatg tatttggtaa catcaggctc actaaattta taataaggct
    16441 taaagctatt cccatagggc tcaaaaacaa ctgtttgtcc ttcatcataa gactgtgcct
    16501 tgatggttga aggctgaacg acaagcaacg ataagaaaaa tgtaaacaag catagtgtac
    16561 gaatagctat cctttgataa gataactttg cgttatgatg ttgatgagtc atttagcttt
    16621 tcctccttta cagtagtgcc aagagtgtca tcacctaatg atgatgtctg ttgctaacag
    16681 gattagcctt agttgaaatg attacaaact tccttaatgt aacaaacata ataaaaataa
    16741 attatttttt tattatatat tagttaagct cagatgacaa gctatttgat ttttttctga
    16801 gataatgtta caagggattt ctaacaccaa tgactaactc agatgaaggg ctttttcttg
    16861 gaggattgcc tatagttaca atagtaggca agactggcag tcgccatgat acctattcca
    16921 ataacagcaa aggttgctag atgaacagag gctggtatac aggtcatgat ggtagttgcc
    16981 agtggcatta agagaatagc agttgtgacg attgagctaa agactcgtcc tagcaatgcc
    17041 tcaggaactt ttttttgaac gatagaaaag aagtgaatgt taaagattgt taaaaagcat
    17101 tcaaaccata aattcccaag ggcaatcaca atgactggaa gcttcaagag agccatagct
    17161 gttattagaa gcatccctag gccactaagg cctagggata ggagtaagct ttgctgatta
    17221 tttttaaaga gcttgttagc cataaaagct cctaagatag cccctaaagc tcccatcgaa
    17281 agaagactag catagcttga ttggctgcct agcagctgat tcgaaaaagg aattaaataa
    17341 ttgaaagcag caataaagaa attcacaaga gaagcaataa tcaacaaaga aaaaatgtca
    17401 ttgtcatggt agatgaattg cagcccctcc ttaatatctg ttaaaagctg aagcctattg
    17461 ccttggctgc tctgtttagt gatgtgcctt tctttgtcct tgattgtata tagacataga
    17521 aaggacaata gaaagctaat gctatctaga gccaaggctg ttttgatgcc aaagcaatcc
    17581 atcactaaaa aagcaagcat tggtgaggaa atactgatga tttgagatac gatttctagc
    17641 tgagcattga aatgaacaag tctttctgtt tcaactagtg tgaccacata ggctcgaaaa
    17701 gcagttccag agaaggcata cgatattgct aaaagagcat taacagtgat aagcccataa
    17761 agcatgatag tagggttagc tatcagggct aaaagtccgc agctgatagc tccgatagca
    17821 tctgtccaca ataacaattg tcgtcgttta taacgatcag caatggcgcc accgatagga
    17881 tttaagatga gtgaaataag gccttcagct agctgataat aacccaaata ttgtcggcca
    17941 gttgctccga gtccagcaat cccgctgctg ttgctgtagt cgtaaacagt attgcctatt
    18001 ttgttaatag ctcgacttgc gagcagctgg tagtcgtttt tgcgcatgat aaaacctcca
    18061 aaagattatg tggttttatt ataaatcagt tttttagggt cttatgtttt tttgcaaata
    18121 aggctagagg aggctacaaa tctttcaaaa tccttttggt aattgtgcgc taggtgagga
    18181 caatccaggc tctcaaaaat ggaaatagca gtagtcatat ccttaatgcc agacaaacac
    18241 tgtcctcttt ggtagtcctc taagcccttt aaaaataaaa agatggtttt ttcatatagc
    18301 ttggtttcat tattgagtag ggctagtatc tgcttttgat aatagcgcgc atagtcaagc
    18361 tgatgtcggt ggatacaggt ttcccaaata ttgagaaggg tgatggtaac caaatgctta
    18421 ttggttgaaa tgctttcgta gtaggtatga ttgtttagaa tttcctttcc cattttatct
    18481 aataagggaa tatcaataaa aagatagaga tttccaatta aaatcagctc atagatatgc
    18541 cagctttcag tcctaaaaag gtagtcagtg acctcatcaa gataagcctt aggaaaagga
    18601 atgctaggat tgcatttaca gataaagcct tggagtagaa tgctgtttaa atagtaacga
    18661 ttggtatcag gatcagcttg gtgctttgcc aattcctgct tttgcagctg cttgaatccc
    18721 tcaatatcgc gtgcatattc cagcttgatc agctgcgaca tgaattgaat ttgctctgtc
    18781 tgtttgaagt tggcagctat gtccataaat tcgctgattt ccacttgcat gctgtctaaa
    18841 gctgttaaaa actttgttac tgatagatca gattcgccgc gttcaaagcg ggataactga
    18901 gacaaggaca cgtctttact ggcaagctgc tgtaaggtga tatttctgtt ttgtctaatg
    18961 ctgcgaaatg cttttcccaa ctgatgatta gtcatatttt ttcctcctct aatgagtata
    19021 tcatgtaagg cttctgttgc tgtattttcc cgtatgtgca aaccttgaaa cttgtctgct
    19081 gccgccacaa aggcatgaaa acatttacac tttttgatag ctatttttat cattgatgta
    19141 gtctttttcg caacatttgt acgggatcat cagattaaaa ttaagaaact gatgatgtga
    19201 cactgtaaac atgctaaaaa tatgttgaac aatgcctgta gctggaaaat gggtacatgt
    19261 attttcttca tgcctgcgtc gtgacctgct gctattaaag cttgcttgaa agggaaaaag
    19321 agcttataat agcagtgaga acattaaaaa tgaaagtaga gatatgccaa taattgttat
    19381 ccttggactt gctatctttt cggtggttaa ggtcattatt tttctatgct tttataaagc
    19441 atttgagaaa aaacaactaa agaagctaga acaggatcaa aaagaaacca agcaggcgat
    19501 tgaccaagag gagtcaaaaa aagcctttcc cttttaacat aaagctagaa aaagtctgag
    19561 acctttcgtc tcagactttt tttaaggctt atattgtaat tgaccacgaa aatcgtctag
    19621 tgtctggtag cccttttcag ccataatgtc ttgtagctcc ttagtgatac gcttaaaaat
    19681 agctggacct tcctggtgca gtgctgttcc aatttgtacc atagctgcgc cgcataggat
    19741 atgctcaaag gcatcacgtc ctgttttgac accgcctgtg ccaatgatct gaatagaaga
    19801 gttaagccgt tggtaaaagg catgaacatt agccagggca gttggcttga tgtaatcacc
    19861 accaatacca ccaaagccgt ttttaggctt gatgacgacc tgctcatcat caataaccaa
    19921 gccattgcca atggaattaa cacagttggc aaaggctaag gggtattgat tgaaaatggc
    19981 tgcggcttgg tcaaaatgga caatatcaaa ataaggaggt agcttgatgc ctagaggctt
    20041 ggtgtaatag gaaaagatct tttttaggag ctgatctgtg gcttcaaagt cataggccag
    20101 ctgaggctta cctgggacat tagggcacga caggtttagc tcgacaagtc cttgataatc
    20161 agaggcctga atagctttta ggatagtctc ggtttcttca gcagacatgc ccacaacaga
    20221 taaaaagtgg tgcttgcttg cttgatcctt ttgcatttct gtgacaatat ctaaataata
    20281 ctggtagcca tgattaggaa gtcccattga attgattgag ccaagtgctg tatctgcata
    20341 gcgaggctca gggttgccct gtcgaggggc tagagtacct gtttttgtca caaaggaccc
    20401 agcctcagag gcctcaatgg ctagcagctc ttccttggtc atgcaataca ctccagcagc
    20461 gttcatcagg caattattaa aggcaaatgt agcgattttt gtggcagtag aaaccatgtt
    20521 ttcctccatt tttagacaaa ttttttctat tctatcacta gggcatgaga atagcaaggc
    20581 atttttgcaa aatacttgct tgaaggcttt cttttgtgag gttttagcgt ttttcatgat
    20641 attaacaaaa tgattttcaa taaagagagg aatagactag cttttttgac ctattttttg
    20701 taaaatagga gttgtaaaaa ggcaagaagc ctttaaactt aataaggaga tattaactaa
    20761 tggtaaaatt ggttttcgct cgtcatggtg agtcagaatg gaacaaagca aaccttttca
    20821 ctggttgggc tgacgttgat ttgtccgaaa agggaacaca gcaggctatt gatgctggaa
    20881 aattgatcaa ggaagctggt attgcatttg atcttgcctt tacatctgtg cttaagcgtg
    20941 ctatcaagac aactaatctt gcacttgagt attctgatca gctttgggta cctgttgaaa
    21001 aatcatggcg cttgaacgag cgtcactatg gtggcttgac tggtaaaaac aaggcagaag
    21061 cagctgagca atttggtgat gagcaggttc atatctggcg ccgttcatac gatgtgttgc
    21121 ctcctgatat ggctaaagat gatgagcatt cagcacatac tgatcgtcgt tacgctcatc
    21181 ttgatcattc tgttattcca gatgcagaaa acctgaaggt aacactagag cgtgcccttc
    21241 ctttctggga agataagatt gcaccagcct tagttgatgg taaaaatgtt tttgttggag
    21301 cacatggtaa ctctattcgt gcccttgtca aacacatcaa gcaattatca gatgacgaga
    21361 ttatgaatgt ggaaatcccg aacttcccac cgcttgtgtt tgaatttgat gacaagctaa
    21421 atcttactgc tgagtactac ctcggtggtg aataatgctg tgaggccaga cctagctctg
    21481 gctttttttg ttatgtgata aaaaaggcgt ttccaacaga aatgtgatat gatagttaaa
    21541 aagtggtaaa agaagggaat cttatgaaag taaaggaacg ccgagaagct attacagata
    21601 ggttaagcca agcacaagaa gccatctcag caactagctt agccaaggca ttgggagtta
    21661 gtcgtcaggt gattgtcgga gacattgcct tacttagggc gcagcagctt gacattattt
    21721 caacaccaaa gggatatatc ctgtcaaatg ctttgtttag tcatcactat tctgctagaa
    21781 ttgtttgcca gcatggacct gagcagacaa ggcaggagtt ggagttgata ttagcacatg
    21841 atggcattgt gaccaatgtg gaggtagagc accctattta tggcatgctg acagcaccgc
    21901 ttaacattaa aagctcagct gatatcaata actttattga aaagctcgga gcctctaagg
    21961 cagaattatt gtcgtctttg acagagggtc tgcacactca ccttttgtcc tgccctgatc
    22021 aggaggcatt tgaagagatc aagagagatc tagcagctgc aggcattctc tatggtgaac
    22081 aataatctga tagcagctgg cttcacaggg atttagtctt ggcttgatag ccaatgtccc
    22141 tcttttgtcg taggtgatag ggaccgcagg acagctccta gatgctgagg ccaaagtctt
    22201 gtggctgggc ctcaaatgag gttaaaaggg aaggaagctg ctatggttat ggtgaaaggg
    22261 ctagatttac ccttactttt ttgctaggat aatcttttat gctgttaggc cgcagggctt
    22321 ggtgctgcaa tggctgagat gtgtctgtct tttgtcttag cttttggtgc ttgagaaggg
    22381 ctgggattga gcttatgctg tggttgtttt ttgatttgct aggtgtcttg acatctgtcg
    22441 cgtttttggt tatactaacg actagtaaaa ggagatatta tgaccaaaaa accaacacaa
    22501 ctgattgcct actcttctat tttggtggcc tttgccatct tgattccgat gataatgccc
    22561 attaagctta ttattggccc ggcttccttt accctagcta gtcatctgcc cttgttttta
    22621 gccatattta tatccattcc ggtagcgatc ttggtgggga taggaacagg tctgggcttt
    22681 ttgctagcag gatttcctat gattattgtt atgcgagcct tctcacacgt gctttttgca
    22741 gctattgcgg cttttatgct caaaaggcag cctaaatggc tggaaacacc gttaagaacc
    22801 tttgtttttg ggattatagc aaatgtgatt catggcctag cagagttttt agtggtttat
    22861 ctgatgacag caacagcagc aactgatctt tcttattttt ggtcaatgct aatgcttgtt
    22921 ggctttgggt ctttgctgca tggtatggtg gatttttatc tagccttatt tatctggcgc
    22981 ttcttaaggc agaagggtca tctatcagtg acaagctagg atttctgtga gtatttatgt
    23041 tttagtagcc aaggctgtta caggctgagg ctcttttttc tgaaagcgct tgcatttttt
    23101 tgaaaaaatg ctatactaaa gagtgcgttt gtaaatatac taacaaaagg agatgtcatg
    23161 aaaacaccag aacagatatt agccgcgacg attacgattg gtgagcataa ggttgcaaag
    23221 ccttttttgg ctaaggctat tttaggcttt attggcggtg cgatgattag tttgggctac
    23281 ttattgtatg ttaggattgc agctagtggg ctggagacct ttggcgcttt ttctagtatt
    23341 ttgggtgctt gtgcctttcc gattgggctg atcattattt tgatggctgg cggtgaattg
    23401 atcacaggca acatgatggc ggtgtcggca gccttttttg caaaaaagat taaggccaag
    23461 gacttgatgg ccaattggct ggtgattacc ctttttaata ttttgggagc cttgttcgtt
    23521 gcctttgttt ttggtcattt tctgggtctg acagctactg gcagctttaa agaagaggtc
    23581 attgaggtgg cccatgccaa gcttgctgca actcctctac aggctattgt ttcaggaatt
    23641 ggctgtaact ggtttgttgg cctggcgctt tggctgtgct atggcgctag tgatgcgaca
    23701 ggtaagctcc ttggaacctg gtttcctgtg atgacctttg ttgcccttgg ttttcagcat
    23761 agtgtggcca atgcctttgt tattccggcg gctatttttg agggtggcgc cagctggatc
    23821 gattttgcga ctaattttgc tctcgtttat gtgggcaatg tccttggcgg tgctatcttt
    23881 gttagtctct tttattacaa ggcttatgat cactctaagg aagcctgatt agtgctgtta
    23941 tatttttaga ctgggagacc ttattctcag tcttattttt atattttgtg ataaaatagg
    24001 aaacgacgtt taaaaaggag gagttgataa gcatctaata tggcatcatg gataaaaaag
    24061 aaaaaagcaa gcattcctag gcgaattcat ctcctttttt tggtgattgt ttttttgttt
    24121 gttgccctga ttttgagatt ggcacaaatg cagatttatg agaaggattt ttacaaggca
    24181 aagctgacag cgtcaaccgt ttacaaagta aaaagctcta tgccaagggg aaccattttt
    24241 gaccgtaatg ggaaggttct agtttctaat cgtatcaagg acgtggtaac ctatacgaga
    24301 agtcccaagg ctagtgctaa ggacattaag gctttggctc atcagctagc tgcttatatt
    24361 agctatcctg aggctaaagt gacagtcaga gccaaaaagg attattattt ggcagatcca
    24421 gaggcttatg ctaagacggt tcaagcctta ccccaaaagg acaaggtgga tcgctttggt
    24481 aataaattag tcgaagcaca gatatatcaa aatgcggcag cctctcttaa ggaaacagac
    24541 ttgacctatt cagaccaaga gctaaaggtt attgctattt ttaaccaaat gaatgcagca
    24601 gctgttttta gcactgtaaa gctcaaaaca tcagccttat ctgagcagga tattgccatc
    24661 attatggcca ataagtcaaa attaccaggt atttcagttg ggacagactg ggagcgtcag
    24721 gtggaggaga caagccttgc tgctattatt ggaagggtct ctagtgagga agccggtctt
    24781 ccaaaggaag aagcaaaggc ttatcttaaa aagggctatt cgcttaatga tcgtgttgga
    24841 acctcttatc tggaaaagca atacgaggag gtccttcaag gaaagcatga aatcagagaa
    24901 atcaaaacga gcagatctgg tgaggttatt tcagataaaa tagtcgaaaa gggtcagatg
    24961 gggcggaacc tgaagttgag cgtgccactt gattttcaac agggcgttga gcagatcttg
    25021 aatcagcact tccagacaga gctcaaaaat ggtcaggctg cttactcaga agggatctat
    25081 gctgtggcgc ttaaccctaa tacgggagcg attttagcga tggcaggtct atcacacaat
    25141 cccaaaaccg gtgagcttca aaaggacgct ttagggacta ttactgatgt gtttacacct
    25201 gggtctgttg tcaagggggc gaccttggct gccggctggc aggctggagt gattcagggg
    25261 aatcaggtct tgattgatca gccgattcaa tttggtggct cccagccgat taattcttgg
    25321 tttaccagcg gtcagcaccc tattactgct agtcaggcgc tggaatattc atcaaatact
    25381 tacatggttc aggttgcctt aagaatgatg gggcaggatt acgtgactgg tatgaccttg
    25441 gccaatactg gtatgaagga aaccatgaaa aaattgcggg cagcctatgc cgaatttggc
    25501 atgggagtgg caactggcgt tgatttgcct ggcgaatcca gtggctacct catagatcaa
    25561 tataatactg caaatgtttt gacagaggcc tttggtcagt ttgataacta tacaaccatg
    25621 caactggccc aatatgtctc aactattgct aatggcggca gtcgccttgc gcctcacatt
    25681 gtagaaggca tttatcagga taatgaccag tcaggaccag gtaagctaag taaggctatt
    25741 gagactacct tgttaaacaa ggtgcactta gctgctgata gtttagcgat tattcaggac
    25801 ggtttttatc aggtggtcaa tagcggtagt ggctatgcta caggtagggc tcttgcagga
    25861 ggtcctgtta ccattagtgc taaaaccggt accgcagaaa cctatgctaa ggataaaaat
    25921 ggtcaggctt tatctacctt taacttgaat gttgttgcct atggtccgag tgctagtcct
    25981 caaattgctg ttgctgtcat gtatcctcat gcgacagact ctctagccaa ggcacatcaa
    26041 tacgtggcta aggatatcat taatttgtac atgaagatgt ataaaaacca ataaaggaga
    26101 aacgagtgct ttaccctata ccaatcgcaa aattaattga aagctattct aaattaccag
    26161 ggattggtgt taaaacagcg acaagattgg ctttttacac cattggaatg tctgatgagg
    26221 atgtgaatga ttttgccaaa aatttattag cagctaagcg agaattaacc tattgctcta
    26281 tctgtggcaa tttgacagat gatgatccct gccatatttg cacagatagc agtcgggata
    26341 aagagatcat tttagttgtt gaggattcca aggacgtttc tgccatggaa aaaattcaag
    26401 aatatcatgg ctattaccat gtgctgcatg gcttgatttc tcccatgaat ggggttggcc
    26461 cagatgacat caatctaaag agcctaatca cgcgtttgat ggctggagag gcaacagagg
    26521 tcattgttgc aacgaatgcc acagcagatg gagaggcgac tgcgatgtac atctcacgtc
    26581 tcctaaagcc tgctggtatc aaggtgacgc gattggctag aggcttggca gtaggatcag
    26641 acattgaata tgctgatgag gtaaccctgc tgcgagcgat tgaaaatcgg acagaattat
    26701 agcttagccc attttcagct ctctgtcatt agcccttatg ccatgtgata aggccataaa
    26761 ggaaggcaga ttttgtcaga gtcttttgaa aagcaagctc gtttttgtta taataagtgg
    26821 tagtctaatt cagataggga aggttatcaa tgtctaaaca aaccttaatt ttattatacg
    26881 gagggcgttc ggcagagcgt gaagtatcag tgctttcagc tgagagcgtg atgagagcag
    26941 ttgattacac caaatttttt gttaaaacct attttatcag ccagacaggt cagtttatca
    27001 agacacagga attctctagt cggccgacct taacagaaag gctgatgacc aacgacacta
    27061 ttaggctaga gcagcagata aggcctagtg atatctacga ggagggggct gttgtttttc
    27121 cagtcttgca tggccctatg ggagaggacg gttctattca aggcttttta gaggtgctaa
    27181 aaatgcctta tgtgggaact aatatcctct catcaagtgt tgcaatggat aagattacca
    27241 ccaaaagggt cctagagtca gctggtatcc cacaggttgc ttataccgtt tatattgagg
    27301 ggcaggattt agacaggtgt ctggcagaga ctgaggcagt cttaagctac cctgtgtttg
    27361 ttaagccggc caatatgggc tcatctgttg gtatttctaa ggcagaatca gaggaggagt
    27421 tgcgtgcagc tatcctgttg gccttgacgt atgacagtcg tatcctgatt gagcaagggg
    27481 ttttggcaag agagattgag gttggactgc ttggtaatac cgatgtcaaa tcaacccttc
    27541 caggagaggt agtcaagaat gttgactttt atgattatca ggccaaatac attgataatg
    27601 agatcacaat ggctattccg gcagctattg acgaatcagc tatgacaagc atgcgtacct
    27661 acgcagaaac agcctttaag gctattggtg cttgtggcct gtcgcgttgt gatttcttcc
    27721 ttggtcagga cggtcagatc tacctcaatg aattaaatac catgcctggc tttacgcagt
    27781 ggtccatgta tcccttgctc tgggagcata tgggactgag ctatgctgag cttattgagg
    27841 agctagtcag attagcacag gaaatgtttg aaaagcgtga agggcattta atataagaga
    27901 caaaggacgg aaggagatat agcaatcctc tgtcctttcg tttggcctga ttggtagcgt
    27961 tttttggtca gaagccttta aagccctatc gtctacggtt ggctgtgcca gctttagcct
    28021 gtctatgaag gatcagcctg taggcataaa gtgaaataga aagaatattc ctaatatgtt
    28081 atgctata
//
LOCUS       DARYXZ010000030        28033 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYXZ010000030 DARYXZ010000000
VERSION     DARYXZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28033
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(298..813)
                     /locus_tag="TV186_001179"
     CDS             complement(298..813)
                     /locus_tag="TV186_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1532577.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
     gene            complement(815..2326)
                     /locus_tag="TV186_001180"
     CDS             complement(815..2326)
                     /locus_tag="TV186_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1532578.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            complement(2316..3041)
                     /locus_tag="TV186_001181"
     CDS             complement(2316..3041)
                     /locus_tag="TV186_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1532579.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            complement(3570..3992)
                     /locus_tag="TV186_001182"
                     /pseudo
     CDS             complement(3570..3992)
                     /locus_tag="TV186_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4136..4642)
                     /locus_tag="TV186_001183"
     CDS             complement(4136..4642)
                     /locus_tag="TV186_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532580.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            complement(4644..5570)
                     /locus_tag="TV186_001184"
     CDS             complement(4644..5570)
                     /locus_tag="TV186_001184"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532581.1"
                     /translation="MNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVAREKL
                     INTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDNGA
                     VSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGRGK
                     SGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSFDQ
                     IGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSMES
                     TGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            complement(5712..6134)
                     /locus_tag="TV186_001185"
     CDS             complement(5712..6134)
                     /locus_tag="TV186_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532582.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(6457..6717)
                     /locus_tag="TV186_001186"
     CDS             complement(6457..6717)
                     /locus_tag="TV186_001186"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532583.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(6732..8540)
                     /locus_tag="TV186_001187"
     CDS             complement(6732..8540)
                     /locus_tag="TV186_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532584.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(9181..10080)
                     /locus_tag="TV186_001188"
     CDS             complement(9181..10080)
                     /locus_tag="TV186_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL1532585.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(10092..10901)
                     /locus_tag="TV186_001189"
     CDS             complement(10092..10901)
                     /locus_tag="TV186_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1532586.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TV186_001190"
     CDS             complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TV186_001190"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL1532587.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(11736..12476)
                     /locus_tag="TV186_001191"
     CDS             complement(11736..12476)
                     /locus_tag="TV186_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1532588.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(12480..13778)
                     /locus_tag="TV186_001192"
     CDS             complement(12480..13778)
                     /locus_tag="TV186_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1532589.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(13790..15136)
                     /locus_tag="TV186_001193"
     CDS             complement(13790..15136)
                     /locus_tag="TV186_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1532590.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(15581..17026)
                     /locus_tag="TV186_001194"
     CDS             complement(15581..17026)
                     /locus_tag="TV186_001194"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL1532591.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(17628..18341)
                     /locus_tag="TV186_001195"
     CDS             complement(17628..18341)
                     /locus_tag="TV186_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL1532592.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(18469..18975)
                     /locus_tag="TV186_001196"
     CDS             complement(18469..18975)
                     /locus_tag="TV186_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL1532593.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            19358..19636
                     /locus_tag="TV186_001197"
     CDS             19358..19636
                     /locus_tag="TV186_001197"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532594.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TV186_001198"
     CDS             complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TV186_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL1532595.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(21225..21671)
                     /locus_tag="TV186_001199"
     CDS             complement(21225..21671)
                     /locus_tag="TV186_001199"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL1532596.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(21873..22640)
                     /locus_tag="TV186_001200"
     CDS             complement(21873..22640)
                     /locus_tag="TV186_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL1532597.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(22802..24598)
                     /locus_tag="TV186_001201"
     CDS             complement(22802..24598)
                     /locus_tag="TV186_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532598.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISASKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(24598..26307)
                     /locus_tag="TV186_001202"
     CDS             complement(24598..26307)
                     /locus_tag="TV186_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532599.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(26300..26749)
                     /locus_tag="TV186_001203"
     CDS             complement(26300..26749)
                     /locus_tag="TV186_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1532600.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            26959..27978
                     /locus_tag="TV186_001204"
     CDS             26959..27978
                     /locus_tag="TV186_001204"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1532601.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         8374 a         6756 c         5153 g         7750 t
ORIGIN      
        1 ctctattttc ctttttcagc ccttgtatac tggggaggat ataatagccc ccctaaaata
       61 aaatgtgcta agcaatatga gaaacaggtc gctgagcttt tcttttattt gccacaaggc
      121 acatacgaca gctgttaaca tttaaataga ggttaaaaga taggacaatc aaagcctgct
      181 gattgctgac aataataaaa gcaccccaag gcattgaccg acttagccaa gtgctggggt
      241 gcagtttttt catatgacct tttagttgtc atcaaggact ggatcgatag cctctagcta
      301 gagagtagcc tttagcctaa cttggccgac ttctgcccta gcagcaactg ctccagcatc
      361 agcaagacgc atatcagcaa tgtcctgtga gtttgtaaag acaaccataa cggtgctgtc
      421 tttttgagca gcttcaagca ctggcaaaga gacctgagcc aataactgcc cagctactac
      481 ctcctgacca gcaacaatat cagagctaaa ggcagcttct cccagctcaa cagtatcaac
      541 accgatatga atcaagacct caagaccagc tggagtaacg atgccataag catgcttggt
      601 cggaaaaacc gtcatgaccc ttcctgttac gggtgcataa atagcgccct cctgaggaat
      661 aatagcaaag ccatcgccca ttagcctttc tgaaaagaca ggatcactga cactggtaat
      721 aggaactaat tgtcccttag ccactgataa aatacgatcg cttaacgcat cagctttttt
      781 tgctgataat aattgcttcc acttctttat catgttaatc ttctctacct aatagttgat
      841 tgatttcttg actatacaag atagccttac caccataaat agcctgaatg ccatttttaa
      901 catctaatac agctgttgct cccagtgagg ttaaaacatt cttgttaacc aagctgctat
      961 ctgacagaga cactctcaag cgagtcgcgc aagcggttac atcttcgatg ttagcttgtc
     1021 ctcccaaagc ctcaataata gctaatgaca cctcacgaag tgatgagctt tgagtattag
     1081 tagtctctgc ttgtccttct gcttctacct gagctaccat tcccggtaca gcaacctgga
     1141 atttgctcac aaagaattta aagacaaagt aataaaccat aaaccacacg ataccaacag
     1201 ggataacaag tagccagttg gtatgatcat ttccttggaa cacaccaaag attaaaaagt
     1261 caatcaaacc acctgagaag gaattaccga tacgaatctt taataaatca gcaactaaga
     1321 aagaacaacc atctaagaaa gcatgaacta catagagcca aggggctaca aataaaaagg
     1381 caaattcaat aggctctgtg atccctgtta gtaaggaagt caaggcacta cttgaataaa
     1441 agctaccaac ctttttacga ttagcctttg gaatagcgtg atacatagca agacaggcag
     1501 caggtagtcc aaacatcatg gttgcaaaac gtcctgcaaa aaagcgtgtc ccgtaagtaa
     1561 acaagtcggt atggttagca tcagccaatt gcgcaaagaa gatattttgt gctccttgga
     1621 tagtctcacc tgctacaacc tcactaccgc caagtgatgt ataccaaaac attgggtaaa
     1681 tggtgtggtg cagccctact gctcctgtca gacgtaaaaa gaaaccgtac aagaatgttc
     1741 cgatgctccc catatccgca attttttcac caaacactac taggagattt tgaataggtg
     1801 gccaaatgac atagaaaaca ctaccaatca caatcgctgc caatgaggaa acaatcggaa
     1861 taaaacgaga gccgccaaag aagcctaaaa aggctggcag ttcgatcttt cggtacttat
     1921 tgtgaaggct aacaacaact aagccaaccg tcaaagcccc taaaacaccc gtatcaatct
     1981 gagcgtcctt tgctgaaaaa agagtcagat agccgctaat ggttgccgta aagaccaaat
     2041 aagccacagc acctgaaaga ccggctgttc ctttatctcc gttggctaag ccaacagcaa
     2101 caccaatcgc aaaaatcaag gcaatattag caaaaacagc gttacctgct gtgctcataa
     2161 tggtaaaaat agcctgtagc catgcttgat ttaatatcgg aaattgtgca atggcattgc
     2221 tatttgacag ggccccacca atccccaaca acaaaccagc aactggtaag attgagatcg
     2281 gcagcataaa ggcttgaccc aattttgaaa atttcttaaa atccatgtga tttctcctcc
     2341 ttcttgagag ccgccacaaa gcgctctgca atttcctttg gtctggtaat agcaccacca
     2401 accacaatac cagctactcc caaagcctga acagccctgg cctcctctgg actatgaatc
     2461 ttgccctcag ctatcactga tacccctgca tcacacaagg cacttatcag ctccatatcc
     2521 ggacctgtcc cctgacgact ataaggcgta taccctgata aggtcgtccc tacaaaatct
     2581 ataccagcct cataggctac tagaccctct tcaagcgtac tgatgtctgc cataaacagc
     2641 tgctctgggt acttcttcct tatcgatcga ataaagtccg ctatcgctaa gccatcatga
     2701 cgctcccttt gcgtacaatc caaggctatc accgctacat ctaaggccgc taaggcgtct
     2761 acctctgcca tggttggcgt gataaagggc gcttgcggag gatactcctt tttgatgatc
     2821 cctatgattg gcagatccgt caccgcttgg atttccttaa tatctcgaac cccattagct
     2881 cttatcccta ctgctcctgc ttcctctgct gcctttgcca tcagaggcat gatacctcct
     2941 gcctctgaat agagaggctc gcccggcaga gcttgacagg aaacgatcag cccgtctttc
     3001 agagctgtca gtagctctgc cttgcttggt ttttcaagca tgctttctac tccttttatt
     3061 aattttagag aacgttcaca tctttattgt agcagatatt aaaacacttt caatagacag
     3121 cccactttta ggaagtactt tcattttcag agaaaaatcc ttgttttctg aaagtatatt
     3181 caatagcctt aagtatggca aagagctagc ctattgagct atttactaat tgatacaaca
     3241 acagcaaaac cttacaagac ataccttctt accataaaag cctttttgcc agccagctaa
     3301 ggccaaatac ggcaatatgt ctcaacaaga actaccttag gtcctattat tgcttgataa
     3361 gcttgacaaa gagacaaaaa agagagaacc agtccagtcc tctctcgcac ccagcttttc
     3421 aagctctaca atacccgtag tgggtaactc caccgcaagg gttatatata gaacttttga
     3481 ttgtacccaa aaataaccac ttttcaccta cctaatacag ctaacaacgg cccctaacat
     3541 agctgccctc agatccgcta tcttaaacat tatttcaaag gactgacata atcatctggc
     3601 agttttccct tccaatctat ccatttttgc tccgcaattg gaattagttt tcttagctct
     3661 tcttaggtaa acagttccca actggttgga tctgcaatta atgctattgg ggatctttgt
     3721 agaaatgctt tatcactagc tattttctcc tcttctgttg gcagccagca gttatttttg
     3781 acataaaaat ctatttctaa taaaaatttt cggtcacttt ccagtaattg gaaaagctca
     3841 ttagggagtt tatacactac tcgttgtaca gcaattcctc cttcttctct gactagataa
     3901 tattctccct gatgcttcca aacctgttgg ccataaccct tgatttcctc atattgacta
     3961 acatcttccc atgttaattg actgcgtgcc atgtgtgtta tctttcgttt ttatagctta
     4021 atcgataaat actgctcaat ctttttccaa taataccctt acctcgtctg attgaaaagc
     4081 atactctatt tttatttaag ctatttcaaa tccatttttc aagtattcat ctaaactatt
     4141 tgcaattttg agcttcaaga taagactgta cctgaggaat tttttgaaac atgtttttta
     4201 taaaaccaac catcgctttt tcatcatcag tcacgatatt ttcaggagat aaccttttaa
     4261 cagaaaaaac taaatcaggg atcataggat taaaatcaat ataaaaggaa aagttcttct
     4321 ttagtagttt gttgttcttt tgatagaaaa tatatgacac aacttgatat aattctacaa
     4381 cattttttga agttgagaat tgagacagta ttctttcagt ttcatgtggg ataatgctat
     4441 ctcctaaatc atacaaggga tacaagcagc gctcaataag cacatttata tctgtgatcg
     4501 attgaaaata tgagtcttta gcatttattt taaacccaga atcccctcta aagcacttct
     4561 ctaagtgtcc ctttgaacga gcatctaagt aaagttgtcg acgtctttca tcaacgtcat
     4621 tgttaaaaaa tgtttgtgtc atattaatta cctaattttc taattataaa ttgtccttca
     4681 acaatctttt tagtgccatc tttcaaaacg attgtaggat tattcaaggt ataaattcct
     4741 gttgattcca tacttaataa tacatcctcc aattttaagt tactagtatc aatagatggc
     4801 atcattaatt cagactgtga caaagccata tttttacctg cccaagtttt agcccctgga
     4861 atatttaaaa gtgaagaacc tggagtttta ccagtaactg ttctcacttc accgatttga
     4921 tcaaaagatt taacaaactg aggactatat tcatactgaa atgcaccaga caaatactta
     4981 ccttcatcta cccctttgat agcctctatc ataccggaag aaactaaatt accactacta
     5041 tcataaagta atgctatatc ttcagccata cttgttgcaa aatttcccga tttacctctt
     5101 ccaatggtac catattgctc aattgcatta tacaaatctt gaccattcac aattgatgat
     5161 gcacctgtct taatataaag ctgttttata ttctttataa agccatctaa atatatatag
     5221 ttcttatttg aatacatctt ataaaaatct gcttttgtag aaacagcacc gttatctact
     5281 gataattgag cataatcatc taatgtttct acaaattcat cagcctgtct tatcgaaacc
     5341 caactatttc ctttaagatc cctattaaaa atttctatgg ctttctccct aaatgtgata
     5401 agatttagat cagcattctg ttttcttaaa gtattaatta acttttctct tgctacatag
     5461 ctcttaaacc ttgagctctc tgttgccagc ctgctgtttt caaggttctt caaaagctgc
     5521 tggcggttgt aggtcggttt cgtcacccta gctgctattg gctcattcaa gctaaaccgt
     5581 ctggcggcgc ttggagacgc ttggcattgg cttcaaggtg acgagctact ccctgataag
     5641 ctgtcgcagg ctaattatta agaacatgct ttaaaatagc agagctaatc tcggctccgc
     5701 tatcttaaac attatttcaa aggactgaca taatcatctg gcagttttcc cttccaatct
     5761 atccattttt gctctgcgat tggaatcagt tttcttagct cttcttgggt aaaaagttcc
     5821 caacttgttg gatctgcaat taaggctatt ggggatcttt gtaaaaatgc tttatcacta
     5881 gctattttct cttcttccgt tggtggccaa caatcatatc gcaatttaaa agcaatctcc
     5941 cctaaattcc gttttccttg ctccaataat tcaaataaat catacggcag ctcatatact
     6001 actcgctgct cagctatacc accttcatta gtcactagat agtaagttcc ctgacgcttc
     6061 cacacctgtt gaccataacc cttgacttcc tcatattgac taacatcttc ccactctaat
     6121 tgactatgtt ccatgtatgt tctcctttac ttgtactgat atctttcata actccctctg
     6181 gcatatcacc cggataagta cgacctccag gtcgccacca gctattagca cccttttcat
     6241 taccacttgg aatagaaatc cctttctccg aaacaacctc tggtgaaaca tctaagcgat
     6301 agagcggatc attgccaaga taaccctcgt cgaagccgag taagctttca taaaagattg
     6361 atgcatagtc agcttactct tgttcctcct ttcttcagtt ttttatcata atttcatctt
     6421 aaaatttaat caattcgagc aatctaatct cactcatcat ctccttttcc tatttaggca
     6481 tacttctaag tccttcaaag tttttaaaat tggactatca tactgtgttg tatcatcaac
     6541 aaattgtcta gctaaacttg aaaaattaat attcccaaca atccgattat tatcaatatc
     6601 attagtcaaa acataaagat ctcttaatat tcctgaatag tttttttgct tgggatactc
     6661 aagttctatt aactctctaa gcctttgtgt atattgaaaa cagttattat tatccataaa
     6721 tttctccttt tttagttagg aacgatcctt atttcttgaa tccactccaa tggccaccga
     6781 ttgggaagta agacctgatc tccacctcca attaaggttg ttcctgaaga tttaaccgtc
     6841 tgtggggcaa ccttgccaat attcaattga ctcccctttg gtattttaat tacagcctca
     6901 tattgtctag tatttttcca ttctggaagt aaagctgtat ctatttttgc ttgtatacga
     6961 ttagttgcag gcaccgttgt gacaaaaccg cctccagcat ctgacgcccc tccaaaagtc
     7021 ctataaagtg ttatttcctc acctgtaata actgttctat agtgactatc tgtaaatgaa
     7081 tctgcaatcc aaccaggaag attttcctta gccccaactg ttactttact atctatttga
     7141 gttggatatt ttgtaacact ttcttttttt atatagcctc cgaaattaga actctctctc
     7201 gccagcctgc tgttctcaag gttcttcaaa agctgctggt gattgtaggt cggtttcgtc
     7261 actctagctg ctattggctc attcaagctg aaccttctgg cggcacttga ggcggcatag
     7321 cctgctagga tattccctac caaggtagct ctttgggcat cttgctcact gccgcctaag
     7381 agcttggtgc catgatagct ggcctgacca ccgataaagc cgccaacctc accgatcgta
     7441 aactctgtca agcccttggc aacactcttg gtctgaccaa tcagaattag tgctgcactg
     7501 gctgttgtga acagcccgcc gatctggtga taaagcctgt cattccccat gaacaaggta
     7561 tcccgaaggg gattggtagc cactgtaagc ccatcgccaa cgctacctag ataaatgttg
     7621 tgcccagcct catacaggtt cgacgcccca taagcaactg taccactgcc aacaacaaag
     7681 gccccaacca ccaagggagt cgctgcccct gctgtcatga cgatagccgc aaccccaacc
     7741 gctattgtca caaggctgag tgctagatct atccagccct gcttggccct gtcctctgca
     7801 gctactgcct caaaacgggc atgatcccgc tcctgcgctg cttggagacg cttggcattg
     7861 gtctcaagat gacgagccac cccctgataa gctgtcgcaa agcgttttat ggtgttgagc
     7921 tgtcctatat ccccaacctg atagctccca gcccgcttgg gcttactgct gtactctgct
     7981 atcaaggcct tggtcgaagc caaaagctcc ttgaaggcgg ccaagtcctg actggcatga
     8041 ttgctttcgt attgaatgat ggcctcgtcc aagcgatgga tatcagtgat cagctcacta
     8101 taatccacta ctgtcttggc atgactgaca ccagagtagt gaaccaggtc tgataactta
     8161 gctctggtat tctgtagtag ctcaagctga tccttgaggt gggcctgcga gagccgaagc
     8221 tctgactgca gggtcttaaa gacctgaccg ggtaactggg catgactatt actgtctatc
     8281 tggtaatagc cgtccttata cagcaagagg ctagctgagt aatcattcat caggctttgc
     8341 agggtttgta aaagtgtccc atgcacctca ctcagatagc tcttgattga gctagcggtc
     8401 tgaccctgaa ggcgactgtc tccaatcaag gctgacaggg cggtctggat actcgttatc
     8461 ccatctcccc aagcactgat cgtggtttgg gtgctttgtt gaagggaggt aatctcatca
     8521 tatttgatat tatagctcat ttcttcccct aacgttttca atgcgatatc aaaatgtttc
     8581 accaataata gcaatacatt tctttaatat acctctttta ttatatcaaa aaaaacttaa
     8641 tgattatcac accaagctaa gagcattgat gggtaataac atatagctta tccaaccttg
     8701 ttagcaggag tattacaaat aatgtattgc caagaggaaa agctgatata aataggtggg
     8761 acaaacgtgg tcaagaaaac ctttaacacc aagaaaacca tgataattct tgataacatc
     8821 aaatagtgcc tcagctaaat gattatgatg acctttacca aatcattctt tattatctgc
     8881 aagaaaagaa cagtgacatc tcttcgatcc gattacgaat ataaatcaag cttcaaaacc
     8941 gctcttagta cctttattcg ttgccaaaaa tatctcattg aactctctta ttcaaacgct
     9001 aagctagaag caaccaataa actgagcaaa aacataaagc ggcaagcttt ggctttagga
     9061 acttcaaagc taagattccc aatactttta acatcacaaa agagagcacc aagctggtcc
     9121 tctctagata ttagttatta gtcaccccac tacagttgac attgagcctc tttgatgaca
     9181 ctagtcgtga attagtgaga caacaacata gcgattaggg tcgttgccct ctgaatagct
     9241 ctcaacccca tcaatagcag aaactgtttt atgaacaatc tttcgctcgc tgttactcat
     9301 aggatccatg gtataatctt gaccagactc aagcacacgc ttggatacct ttttggtaaa
     9361 gtcaatcagg gtttctgtcc gatgctctac ataatcatga acattcaagg agacagaaaa
     9421 attcttagaa tagcggtcat gtaagaaatt ttgggccagc aattgcagtg atttcaaaac
     9481 cttaccatga tagccaataa cacgacctgc ctctggtgtc tctatctgaa gattgatctg
     9541 acgacgattg ttggtcctct caatagaggc ttcaatatcc atctcataga taatcttggt
     9601 cacatagtca gaaatctcct gtgcagctag ctcaatatcc ttactcatgt ccgctgcagc
     9661 tggatccagc tgactcgcac cagcagctga cgacacaggc tgtgcctttg actgagtagg
     9721 agctgactga gctgtgctta atggacctgt tggctgatga gcatcagact cagcagccct
     9781 tctgtcttgt gatcgaacag ccttcatctc ctcaagctcc acctcatcgg ggttaataac
     9841 cggtgcattt tgacggttga tctcctctgg aacactacgt acggcttttt tatcagcctt
     9901 atagactgtt ttttcattaa tgccttcaat atcaacctga gctggctttt taccaaagcc
     9961 caaaaagccc tttttctcct ttgaaatcac cttgatgtgt gcttttagac gtgacaaccc
    10021 caactcttga agtccttttt caattgcttc ttcaacagtc ttacctgtaa acaataccat
    10081 atcctaaact cctattttct tttcattgct ctcttacgag cgcgacgttc cttagctcga
    10141 cgctcttttt cttcatctgc taaacgttgc ctttcggcaa taaccttaaa gggattatta
    10201 aacagcaaga gctgaacaac ctgaaaggca ttggaaactg cccaataaag caccacacca
    10261 ctggccagat taaagcccat aaagaagatg aacacaggca tcacgtaggt catgatcgtt
    10321 atcatggccg tcttttctct agccgctaga ttggttagcc atgttgataa aaaggtaaag
    10381 acagccgcta aaataggcag aataaagaga tgatcatgtc gcgccagctc aacccataaa
    10441 aaggtgcctt ctcttaagaa agccacacga gtcagagact gaaacaaggc aaacatcacc
    10501 ggcatctgaa tcagcaaggg caaaaggctc atgtaaggat tgacaccata ctttttgtac
    10561 agagcttgac tttcttcagc tagcttcata cgagttgctg tgtctttagc agcatatttt
    10621 ttttgcaggg cctttagctc tggttgaatg tcctgcattt tctgccctga cttgatttgc
    10681 atgttaaaca atggcagtaa aagcaagcga atcattatcg taaataggat aatcccaatc
    10741 ccagtcgatc catcaaagga caaccattgg atcgccttgg caaaaaaata aaccaattgc
    10801 tcccagctac tagatgattg tgctgtcacc tctccacgcc cacaggctac tagtagcaag
    10861 acaagcggca ctagggctgc tgttttaact ctttttttca atctcaaaac cttcctcaag
    10921 caattttgct agctttaaaa catgatgtaa attttgtttg actgcttgat aatctaattc
    10981 ctctgcacct ctcctagcaa taacaacgaa atcctcagac ttgaggtgat cacccagctc
    11041 cattaaaaca tgtcgtatct tgcgctttac cgcatttcga gtaacagcat ttcctagctt
    11101 tttgccaaca gaaatccctg ctcgaaaatg cttgtgctcc cctttcaaat ggtaaatgac
    11161 aaattttcga tttgccatgc tctgaccaag cttaaaaatc gcctggaaat ctttctctcg
    11221 cttgacacga tagcttttct tcaaaactta actcccatat ctaaattatt accattatac
    11281 cataaaacat taaaaagcct caacccttat caatgggcct ataataagag attggaccca
    11341 ctatctaaag gatcagaaca aaaaatgctt ttagtgaatc acggtagctg tcaagtcttg
    11401 atagccttat caatcatact agcaaagaaa caaaaaaata aagcccggta aaccgagctt
    11461 tatctccgct gacttgagca tcagcaaata tgatatccaa acaaagacaa ctgaaacaat
    11521 cattttaata acaagcagcc atatcaaaaa tactatttgt ttatggagag agagagaaaa
    11581 caatattttg attgaattgg ggatggacca ctccattacc taatgatttc gtaaatcttt
    11641 attcatacta gacattatag cgaaaaatca ctaaaaaaga tgacaatttc ctgaaatgtt
    11701 catttttcgt cctaaaatgt cattcaactt aatttttagc gaaaagactt ccacttttca
    11761 aaaagctgtt tcattctcaa acgagagacc atacaagaat caccattttc aaaatacacc
    11821 aattgcttag ccttatcaat tcgaacaaca ttgtcaagat tgaccaagta agaacggtgg
    11881 cataaaaaca gcttaggagc taccgcatga atctcagata agttcccata aaattctaag
    11941 cgctctgttt gcgtccacag gcacaccttg tgaggcgttg ttgcagttgc aaaataaaga
    12001 atgtccttat aaggcagctt taggcgggtc tgcggggtct caaacaaaaa catctcttct
    12061 acttgacgac tcgacatcat ctcataggtg tagcgaatac attcctcaat gcgctcttta
    12121 aattgctgac tatcaaccgc tttatcaata aaatccaagg cagacacctt gtacctaaag
    12181 gaaatagggg cgaactctga atgcgtcgtg acaaaaacaa gcacagcatt gggatccttc
    12241 tggcgaatat ctgaggctag ctctagccca cttcttgatt tgtcaccaat ttcaatatct
    12301 aaaaaataca gctgatgatc tcctctctcc tgaatgctat caaacagctt ttgaggattt
    12361 gaaaacacct ctaattgatt atgaggaatc ctaccctctt ctaatatgga cgccacaatg
    12421 gcctcaatac gactttgttg aatcagattg tcttccagaa taaaaatgtt tagcatggct
    12481 tatctcattt ctaacaattg tctcaaacgg tagtgatcac ttttggttga aaaggtgatg
    12541 tggggatagc gctctaacac agccgagaac tgtagcaggc gcttatgagc atggcttcct
    12601 agctccaatc ggctagcatc aaattgcttg gcaatatcaa cccgcttgag ccttgtacta
    12661 ttttcaatga taaaaaatcg cttgccatct tgattaaaat aggcaatgga taaaaaagga
    12721 cgagagctgc ctttagctga caaaatagca ttatcaataa ctaccttgaa aagaacgatg
    12781 acatctaaca gcctgacaga agagctagca agcgtttcag gaatatcgat gtaaacagca
    12841 atgccctgca gctttgcttc taatagcttg gcatgcaata ggctgcgaat caccgaatcc
    12901 tgaacattat caagggctga taattcaggt gttagctgcc tgatagagct tgctgattct
    12961 tggataactg tttgatagac cttagaaata gcagctatat ctccactatc aatactatcc
    13021 tttagactaa ttagaatatt ttctgaatca tgcttaatag ccctgatctc acgacaaagc
    13081 cgctcaatat actgattgtg cttttcaagg taagcaacac gctccttttg tgccagagcc
    13141 aatctttgag atagctgatc cttagcaaag cggtccagct tgacaatgac ccagatgagc
    13201 agcatgaggt aaagaaaaat catgacagag cggtaacgaa aataaatctt gaaaaaatct
    13261 ccttggatat tgatcatgca gtgaaccatc acatagtaga aaagtaaggc tgcattcatc
    13321 caaaagaccc acttctttag cttgtcctca ctgataaact taatcaaggt caaatcaacg
    13381 ctaaaaatat agctaaacag gtaaaaggcc ggcaaaacca atgcatgaca gaccatcaat
    13441 agacctatgt cattattgat ttgatgaatg ctgtagccta aaaccgctgg caaaaggaaa
    13501 gagccaataa tacgaaagag cagctcaaca atcataatcg caaacaagcc attaaacaga
    13561 tgctcagaag cctttttatg aggtgcaaag ccaacactga cagcaacaaa caccagctga
    13621 tcaactagca gcacatgatc cagcagcaga ttagcaacaa caaagcaggc accaaccaaa
    13681 agcaatgatc taacagctag cttaatgcct gaaaatgtcg aaaagatgac ccagctattc
    13741 acaaagatca gagcataaaa gaatgacata cctagcataa aataaaactc tactctttct
    13801 ctatttttgg catgattagg gtctgactaa actgataatc atgactcctg gtgcgcaagg
    13861 atagctcagg atatttctgc aaaatccgct tggcattaga caagcctatc cctcgaccgc
    13921 tcccctttga ggaatagccc tcttcaaaaa tcctactaat catgaccctt tcgtccttgg
    13981 tcgtattggt tacggtgaaa atctgctgat catcagataa aaagtaggct atcgccactg
    14041 ctggctgggc tgtctctaga gcagcctcaa tagcattgtc acaaaaaata gatacaagca
    14101 gcaataaatc aagctctgag atatagctat cccgaatccg atctggaact tctaggctta
    14161 aggcgattcc tgccttctca gccttaatga tttttgatga tagcaagctt tttatcgagg
    14221 atacactgat tttactgagc tttgaaatat tgtaatgctt atcgtcccaa taatccgtcg
    14281 cctcatctac cgtttgggca tagacagtct gtacatctga cacagagcca gagtcaatag
    14341 cctgccccag cctttctagc ctcttgaggt aaactagctg aaatacctta acacccttat
    14401 aaagcttttc tagatgcttt ccataggttt ccagattagc aatataagcc tgctgttcct
    14461 tttttaattc ctgttttaag aattcctttg attgatgatt aaaataagac agtaaataaa
    14521 tcaacaatag ggtaaagatg agaaacagca ccttataaga cgttgacatc attatcgggg
    14581 atttaaggtc aagaaaggga tcagtaaatc ctaaaatcat aaagagatca atatagtagg
    14641 ccaaactaaa gagcaaaaac aagctataaa agctactggc cttatcaaac ctgtcagctt
    14701 taacaatctg cttgtaatcc tttcccacaa aataattaat caaagcaaag cttgggaaaa
    14761 tcatcacata agcaataaag tctaggacaa ggtgtctgac atagctgcca ttaactgaaa
    14821 aaatataggg aagtacaatc gctaaaataa agcgtgataa caaatcaaca aacactccgg
    14881 gaacaaaggc caagaataga gcctttaagc taaagcaggg ccgcttttct aaggctaata
    14941 cagctagcag caataaagga tcaattatca agggcggcaa taaagcaaac tgattcaaaa
    15001 agagagctgc tgtcaggaca aaaatctgct tccaaagtgc cagtttaatg tctgataaaa
    15061 aggaaaaaat actaatttct gtcacataat aaatcatcag tgatagtaat aaaaagagat
    15121 aataaatatc agtcattctg cctccttacc aactttatta ttttaacaca ctttgtgtca
    15181 atccctatta tatgaatttt ttatataatt cagcaagcgc aaaaacagtc catagctggt
    15241 ttgtgacagc gtttgcaaat cagatgtcaa tcattaaagc aaattaaaat atctgaccag
    15301 ccttacctta tctagggaaa aatattgtat aacaaataat ctaagaaaac cagtgacaat
    15361 ttaatattta ttttaataat atcttccacg ctcatcaaaa attaagcaga taagcctgct
    15421 ggattatgac atctagctat gcgctactgg gcgtcgtgtc gctagctcaa gcacactaaa
    15481 aaagaatgaa gcaaacatca gatatctcat ctctgcttca ttcatgatgt tatttatgat
    15541 catcgtccag cctagaccaa actactagct gcgatagtgt ttaaagcata ttggcaatat
    15601 gctcaatcga ttgttcacgt ccaaggaggt aaatggtatt tggcagctct gggccatgca
    15661 tttctccaga aacagcaata cgaattggca taaagaggtt cttgccctta atgccggttt
    15721 ctttttggac agccttgatt tgtgggaaaa tgttttctgg cttaaagtcc tcatctgaca
    15781 tcgcctctag cttttccttg aaggccttca gaactgttgg aacagtctca gctgccatca
    15841 cttctttttc ttttgcggtc agctctggga aatctgagaa aaataaatca gtcaatggaa
    15901 caatctcatc agcagagctt aattgaggct gatagagctc aactagcttc tctgcttttt
    15961 cagtcaagcg gcctgctgct tcaagaaatg gcttacaaag cgcatataca gcgccaagat
    16021 cagcatgctt aaagtactca ttgctcatcc agtccatttt tttctgatca aaggctgctg
    16081 gcgacttgct aagacgaatc tcatcaaata aggcaatcaa ttgctcacga gaaaagatct
    16141 cagcctcccc gccaggattc cagcctaaaa gggcaataaa attaaagact gcctctggca
    16201 tatagccttt tttgcggtaa tcctcaataa actgcagggt attggtatca cgctttgata
    16261 gctttttacc tgtctcagaa ttaatgataa gggtcatatg accaaagacg ggtgcttccc
    16321 agccaagcgc ctcgtaaacc atcaactgct ttggcgtatt ggcaatatgg tcatctccgc
    16381 ggataacgtg tgagatttgc atatcgtgat catcaataac aacagcaaaa ttgtaggttg
    16441 gatagccgtc ttttttctgg attacccagt caccaccgac attgccaccc tcaaatacga
    16501 tatcgccttt taccatgtct gtccatttgt aaacaccagc ctcattgacc gctaaacgaa
    16561 ccgtaggcac aatacctgct gcttcacgct ctgcaatata ggccgccttt tcatatgctg
    16621 acatgccaag gtattcattg acatagcgag gtgtttcacc agctgcctct tgacgctcac
    16681 gctctgctgc cagctcctcc tcagtcacat aagacttgta agccttgcct tctgccaata
    16741 attggtcaat gtattgttga taaagggcta gacgctctga ctgacgataa cgctcgtgcg
    16801 tctcaggact ttcgtcccaa tctataccaa gccattttaa attttccagc tgagaacgct
    16861 cgccgtcctc gacatgacgc ttacgatcag tatcttcaat acgaataata aagtcaccgc
    16921 catgatgacg agcataaaga tagttaaaga gcgctgtccg cgcatttccg atatgtaaaa
    16981 ggcctgttgg gcttggtgca tagcgcacac gaattggttt agacattctt tttctcctat
    17041 ggtttcattg aaagaaggga tcctgggcta taaaccgttc ctacggtagg cttgctctat
    17101 gagaaaatgg tcgataagga acaaaaatac agctaatccc ttggaaatct aaagatttca
    17161 atcgctccta ttatagcaca acttcaagca ttgggcgaca aaaatcaact tagaacagct
    17221 gcataacgaa aatgcatgta accattttct agctacatgc attgttttca tctacttctg
    17281 atattttgat atcatcagct gttcacattc agcttaattg tagcctgaat tgatttgaaa
    17341 aagaccatac cactgatgag aaaatcgcta tcaaaaacgt aaagatcctt atgcgtttgg
    17401 cgtggcctag agctaggata gctctataag cagctcattg gcaagcagtg ctgcctcttt
    17461 caatagcttc atagcatgcc tagctataga tattagtcag gctattgacc tgcattgatg
    17521 tcaagctaca ccccagcaaa gaaagcgaca atatactctg gcaaccacga acctgtcata
    17581 tccatttcaa tccatcaatt ggcaaggctt ggtttacttc caactgctta atggccgcct
    17641 gtgacaatat agctctgtaa aactccagca aattgctgaa ggttcaggct ttgcacatag
    17701 acatctccgt atccgctaaa ggtattgacc actccctcac ctgtaccaat agactgcata
    17761 aagccatttt ccaaatgaat atcataatcc aaatcctgac tccaagccac cacatggcta
    17821 ttatcaatcg tcatgctgtc gccatgaagc gtgatttttt taatcgaacc aaaagcattg
    17881 accaataggg ttccttctcc ttgtgttgac atcacaaaga agccaccctg accgctaaat
    17941 aaggccttac caagtttttg gcgcttcatg gtgtagtgag ctgagccatc taaagccaag
    18001 aaggctccgt cattcaaacg gtattgatct acccctagct caagagcaat aacctgacca
    18061 ggcattgaag gggcaagcgc tagcttgcca ctaacatcat tagcaatcgc ctgtgtgata
    18121 aacatggatt ctcctgaaac cattgaacgg ccaatggcac caaccagctt gccaagacct
    18181 gagccacgcc cattgagctt ggtgtttaag ctgattgacg gtgtgtggta aaccatactg
    18241 cctttttgta gaaagacaga ctcccccatg tccaaatcaa tttcaacaag aggaaactgc
    18301 atgctgctgt caatagtata ggtcattcga ttataggcca taacaccact cctttgtatg
    18361 attttgttga tacaatcaag tatagtcttt tttggcagca ttgtccacta gctactgtcg
    18421 ccgccattcc taaccagtct caaagccata ctacaaaccg atcagctgtc aggatttcgg
    18481 catcgccacc tgagacatac gtccagtggc aacatcatag accgcaccac taatgaccac
    18541 gtcttttgga atcaacggtg attgctgcaa tatagccata tcctcacgaa cacttgcttc
    18601 cacatcagta aaggggagaa aatcacagtc agacacatct actcccagag tatcatgaag
    18661 ctgcgctgta aaggcttcat tggtaaaggt ttgcgcccca caatccgtat gatgaagaac
    18721 aacgatctca cgcgttccca gctgctgctg cgaaatcaca agagaccgaa gcatgtcatc
    18781 tgttatccgt ccaccagcat tgcgtaaaat atgggcatca ccaagcgcta aacccaaggc
    18841 ctgcgccaca tgcagtcttg agtccataca ggtcacaata gctaccttag ttttgggctt
    18901 taggggcaaa tgagcagtcc catgtaaggc gacataggct tcattggcag ataaaaagcg
    18961 ttcaaaatat gacatgaata cggtcctccc agactaatct ctaagctatc tcagccttga
    19021 gctgtctgtc tatcttatca tcttttgcct gaaatgtctg aatgctgaac tgctttttaa
    19081 cacaagcaga tagcactagc ctaactgaaa ccagaggtag gtgagccagc cttgacattg
    19141 gaagcaagct tagcagcccg ccctttgagc cgctaaagta agggcagcaa gaacgtgaca
    19201 aaatcagtta attgtcattt taattaaaaa acgaaactac ggagacaaac tgataaattg
    19261 ctatttctcg ctatcagcca gtatgctaaa ctcttctcag aaggccttgg cagtcgctag
    19321 ctgctaagcc aataatacta aattaaggag aatagcaatg aaacaaacaa aaataatctg
    19381 cttattggct gctgctgctg tcctaaccct aggtcctatc agcacaggcc agacacaacc
    19441 acagaccgta tatgccagtc aggttagtgg agacagctgt atcgatctag gtaatggatg
    19501 gtttaaatgt cctaaggata ttggaggatg ggacattctt tttaatcaag attaccaagc
    19561 gccttcacga tcgccatttt tcacttggat ttcaggctgg tttaacttta tatggcagtg
    19621 gtttaaaagc ttctaagatc tactaatacg ctatccatat cataaggctc ttagaggcta
    19681 gctctctaag ggctttttgg ttctacggaa cactataagg accttccaat actactggtc
    19741 ttaaaataaa aaagactagg aatagctccc ctagtcctca tgttaaaaac aacaacctaa
    19801 gtaaagacag cctttaagac ctctcctact gtcgtcacac caacaacctc aatccctttt
    19861 ggcagatcaa tcccctgcaa tgagcttttc ggagcgtaaa gcttggtaaa gccaagctta
    19921 gcggcttcat taatccgctg ctcaatacgg gtcacacgcc gaatatcacc agtcaagcca
    19981 atctctccta aaaaggcctc ctgagggttg gttggttttt ccttgtagct agaggcaatg
    20041 gccacagcaa ctgccaagtc aatagcaggc tcatctagct tcacaccgcc tgctgacttg
    20101 aggtaggcat cttgattttg tagcagcagc ccacatcgct tttccaagac agccataatc
    20161 agactgacgc gattaaagtc caacccagtt gtcgttcgtc tagcattacc aaaaacagtc
    20221 ggtgtcacca aggcctgcac ctcagctaaa atcggtctgc tcccctccat ggtgacaacc
    20281 acagcagagc ctgttgcgcc gtctaatcgt tcctctaaga acacctgact gggattgagg
    20341 acctccacta gcccacctga ttgcatgtca aaaataccaa tctcattggt tgagccaaaa
    20401 cgatttttaa ccgctcgcaa gatacgaaag gtatgatgcc tctcaccctc aaaataaagg
    20461 accgtatcaa ccatatgctc cagcatgcga ggccctgcta gggtgccctc cttggtgaca
    20521 tgtcctacaa taaaggttgc aatatgatta gacttagcta gctggagcag ctcagcagtg
    20581 acctctcgaa cctgactgac cgagccctga acacccgaaa tctccggact catgatcgtc
    20641 tgaatagaat caataatcaa aaaatccggc tgaatggctt caatctctgc tcgaatagcc
    20701 tgcatattgg tctccgcata gaggtaaaaa tcattgtcgg tctgtcccaa acgatcactg
    20761 cgcatcttga tctgctctgc cgattcctct ccagagacat ataaaacagt tcccttatcc
    20821 gcaagctgga tagaaacctg caagagcagc gttgacttac caataccagg atcaccacca
    20881 atcaaaacca agctccccgg cacaacacca ccgcccagca cacgattgaa ctcattcatc
    20941 tctgtctgga tacgctggta gcgaacgcca ttgatatgct ttagcttgat gggcttactt
    21001 ttttctccag tcaggctaat acgggcattt ttgacgtcct tgacctctgt ctcctctaca
    21061 aaggaagacc aggcagagca attagggcag cgccccagat atttgggtga ctgatagcca
    21121 cattctccac agataaacct cgcctttttc ttagctataa cacatttcct ccttgaatct
    21181 aagcatcaac tggctacaag cacgtgaagc agcctgctaa taccttatcc tcctgtcgaa
    21241 ccaaaaccac ctgtccgctc accaccagcc tgatcaccat cagcaatcaa aaaaggcata
    21301 aatacgccct gaacaatgcg ctcaccagct gacaaggtaa tggtttgatc cgtaatattt
    21361 ttcatctgag caaaaatatg cccttcattc gcagggttac catagtagtc accatcaata
    21421 acacccacag aattgatcag aaccagtccc tttttacgag gattgctgga gcgatcatag
    21481 agataaagca cctcaccgtc ttgcatatac gccttgaccc ctgttggcac aagtacaatc
    21541 tcacctggtg caatgctggt ctcctctgca acagataagt catagcctgc tgcatgagct
    21601 gtctcacgtt ttggtaataa atcagtatca gtaaagcctg acacaagctc aaagcctcga
    21661 atccttgtca tgattaacct caagagccct tgtcagtgcc tgcagcagct gtaaaatcac
    21721 ctgccaggac agcagacaaa agcactctta tcccttttct ttttttagtc ctcttattat
    21781 aaaatattcg taaaggaata gcaaaaaagt aggggctgca ccccaaaaat caccgactgc
    21841 ccccctctat aacgcaacaa aatgcaagag ggctaaatct ccttgccggc atagctaaac
    21901 cgaatccttg gaaaatcagc ctccaaatcc ttatctgcca taaaagcctt ggcgtccttt
    21961 ttcacctgaa ccagatcaat cccttgtatg tttgcagcat agacgcagcc gcaatagcac
    22021 tggcggtaaa tatcatattc ctcacacatt tcgaccgacc tgcgatagcc attatttttc
    22081 ttgaaatcac taggcaaata cttagtggtg taaacctttt gcacatcaat gcctacatcg
    22141 ttaatcgtct gtgagttttt atgagggctg atggtcaagg cactagcaaa ataatcaaag
    22201 cccagctcca cagccttttg tgccgtcttg tccaagcgat aatcaaagca aacacgacaa
    22261 cgatccccgc cctcagactc tttctccaag cctcggacag tcttgacaaa ttcatttggc
    22321 acataatctg cctcgataaa ctgcacgcta ttacctgttt tatcgttgaa ctctgctaca
    22381 aatttctgag taacataggc cctgcggtgg tattcgtcct ttgggtgaat atttgaatta
    22441 gcaaaataaa ccgtaatatc agcgtactgg gttaaatatt ccagcgtgta ggttgagcag
    22501 ggagcacagc aaacatgcat caaaatgcga ggacgtatag actccctcgc ccagaccttg
    22561 gtcatctgct gcatgacccg atcatagttt attttctggt ttggattcat tctagctaga
    22621 atctcttgta agtcaatcat tacatcttct accttctatt gtctgtctct tttattatag
    22681 cacattgcct tgacatgctt tgcatcaaaa aactccgcca aagcggagtc gatcggcaaa
    22741 agctgttttg atggttttta agaataacaa cagcagctta tgtaatgatc atttttagaa
    22801 gctactcaaa cacaaactga ttgtgataaa gctcggcata aaagcccttt tgccttagca
    22861 gctcatggtg acttccctgc tcaataacct taccgtcctt tagaacgatg atttcatcag
    22921 catttaaaat ggtttttagg cggtgggcaa tcacgaagct tgtgcgacct gccacgatag
    22981 cctccatagc cttttgaatc ttactttcag taacagtatc aacatttgat gttgcctcgt
    23041 ccaaaatcaa gacctgagga tcggttaaca gcgtacgagc aattgaaata agctgctttt
    23101 gaccagttga aaagacattc tcatcatctg acacctgagt ttggtagcca tcaggcaagg
    23161 acatgataaa ctcatgaata tgcgttgcac gcgctgctgt ctcaacctct ttttggctga
    23221 ttgtctgatt accaaagcgg atattatcag caatagtccc agaaaacaag actgactcct
    23281 gtaggacaat accaacccgc tgacgcagac tatccaagtc atattcccta atatcacgac
    23341 catcaaaggt aatagagcca gcatcaacat cataaaaacg attaatcaga ttcatgatcg
    23401 tggtcttgcc agaccctgtc ggtccaacaa cagcaaccat tttccccttt gaagctgaaa
    23461 tcgacacatc tgacagaatt ttttgtcccg gcagataacc aaagtcaaca tgcttaatct
    23521 caaccccttc ttttaatgct gtaaagacag gagcatgctc agggcgaacc tcttcttttt
    23581 catcgaacat ttcttggata cgaccagcac ctgtaaaggc cagctgcaat tcaccccagc
    23641 tagaggcaat ctgcataatc ggttgataat actgctgtga atactgaaca aaggtcacca
    23701 ccaagccaag agcagcagct gttgacatgg acttgtcacc aaggacaatg gttgagccag
    23761 caaagatgac aatagctgta ttcaaaagac tcatcccatt catcacagga aacagcagac
    23821 cagcaaaaag gcgtccctta aaggttgctg cacgcaccct ctcattgtgc tcaataaagc
    23881 catcaatagc atcctgttgc accccttgaa caataatagc cttctggcca gaaatcttct
    23941 cgtccatgta agcatttaaa gcactgacct ccttttgctg caaatcagta tatttgcggg
    24001 ccattgtaat gatgacaacg agaagaataa gcgccacagg ggttgaggct atcgttacca
    24061 aggccaagcg actatcctgc ctaaacatca tcagcactag accaatatac aaagcaatat
    24121 ttgtcaagac ctgaatcaga gattggttca tggagttttg aatattatca agatcactgg
    24181 taaagcgtga tagaatagca ccgtccttgt gactatcaaa aaagccaact gtcaagcgct
    24241 ccaatttgcc aaataagccc ttacgcatgc gattggtcga atgcgaaata acccttgtaa
    24301 agaggagact ataaataaga ttagccactg ctgtaaagag ataagccaac aatagctttc
    24361 ccataaccgt cctaaaaggc gccatagagg gctcaactaa gggctgaccc gtcattttgc
    24421 taagcgcctg agccttgtaa tagcgctgca cccattctcc cagctcagct agagagtctc
    24481 ccaaaaagac aggggcctta acctgcaggt aggttgccag gacaatagca aagaatatca
    24541 caacaaaaga gagcttataa cgtttaaaat aaaaccagaa aaatcgcagg atcttcatta
    24601 gttctcctct cttccctttt gagtttcgta aatttcacga taaatcggat tggaagcaac
    24661 cagctcagca tgcgtccctt ctccaatcaa tcgaccatta tcaagaacaa gaatcttatc
    24721 tgccttgaca actgacgata ttttttgtgc gatgatgact gttgttgtct ctttgagctc
    24781 cttattcaag gcctcctgaa caagcttttc agatttggca tctagagctg atgtcgaatc
    24841 atcaagcacc aaaatcttag gattgttaat cacaccacga gcaattgaca ttctctgctt
    24901 ttgaccgcca gaaaaattat tgccacgctc ttctacctca ctctggtagc cagcgtccat
    24961 acggtcgata aattccttgg cctgcgcaat gcgtgctgca ttttctaaag ccaattggtc
    25021 agcataggga ttgccctgac gcagattatc cgcaatagtc ccagaaaaaa gaatagcctt
    25081 ttgcagcaca atagagacgg tgtcgcgcag agtctcttga ctgatgcttg gcagagcctt
    25141 accaccaatc aggatttgcc cttcctgtgg gtcaaacaaa cgcggaatca gctgcgcaag
    25201 ggtcgacttg ccagcacctg tcgcaccgac aataccaacc atttgaccgg gctcaacctc
    25261 aaacgaaata tgctttagag tggcttcact gtcatttgga taggtaaagc tcacatcatc
    25321 aaagacaata ctgcctgtca gctcctcctg ctcatggtta acaaaggtca tagcaggctc
    25381 tgtttctaaa atctccctga tccgaccaat cgaggtcaag gcacgacttg cctgcattcc
    25441 cataaaacca accatcgtga tcgcaaagct gatttgtccc atataggtca taaaggaagc
    25501 catatttcca ataacagcag gatctgtttt gaccagccct gaaaccagat acaaggacaa
    25561 ataaatggcc atgtaagaca ccaacatcaa aataggctgc atgattgaaa agccatagcc
    25621 gataaacaaa ttcaagccca gtaggtcatt tgaagcctcc ttaaatgtgt catactggct
    25681 tttttcctga acaaaggact tgaccacacg cacaccgcgt aggttttcct tagcaatctg
    25741 attgatccta tccatcaagc gctggaagat cccaaagcga ggacccatct ggctcatcac
    25801 cagcccaatg actaccattg tcatcacaac cacaagcacc aagacccacc aaaggctcgg
    25861 taaggcctgc accgctaaaa taaaggcacc gacaaataaa atcggcaagc gcaacaatat
    25921 ctgaaaaagc atcatcacaa agttttggat ttgattaata tcatttgtca ttctaacgac
    25981 aagatttcca gcattgaagg cttccacatt ggcataagaa aaggattgga tctttctaaa
    26041 ggtctgctca cgaatatcag cagatacccc ttgagcaatc ttggcagaca agatggtatt
    26101 gaccgcacct gacaccaagc caatccctgc tatcactaac agccaaaaac ccacctctgc
    26161 aatccttgtc tgatcatttt ccataatagc agctagaaca tctttgaggt aatgtggctg
    26221 gagcagggca ctggctacga ccccagaaat catcactagg gacagagccg cataccattt
    26281 atacttcatc acagcatttc taagcatctg tatctccttt ataagctcgt atattttgtt
    26341 tcagctgatc gataaccttt tttaccgtca gcagctcttc tcttgaaatt tccttgaaaa
    26401 aatagcgctc aatatctctg cggcactcct ttaataccgg cagcttagcc ctaccagccg
    26461 aggtcaagac aacctgcttg cagcgcttat ctgtagccga ggcaacaact cgaataaagc
    26521 catttttttc catacgcttc accagattac tcgtaaccga ttttgagatt tgaagctcct
    26581 tttcaatgtc cttgacaaaa atgtctctgt cttgatggca atgcaaaaag acaagaacat
    26641 gcccttgtgg accagcaaga tgctggaggt catacttttt agcaatctct tcgctaattt
    26701 gctcaacctg atgggtcaat tcacgaagct cagcaatgat tcttggcatt tccttcctcc
    26761 ttagttctca tgataaccat tttagttctc ttgggaacta ttgtcaacca aaaaggctta
    26821 cgatctgact atcttccctg ctacttaccc tttgctagca ccactgagct gacaggctag
    26881 gccagcagac cttttctatt agagttaggc cttgtcttat gatataataa ggtgattagc
    26941 tcttaaagga gaataaaaat gccaaaacaa aaggtagcca ttttgggacc tggctcttgg
    27001 ggcacagccc tggcacaggt cctaaatgac aacggacatg aggtccgact atggggaaat
    27061 atccctgaac aaatcaacga aatcaacaca cgccatacta atagtcatta ttttaaggac
    27121 attgtcctag atgaagccat caaggcaacc cttgatttga aggaagcatt ggctgatatt
    27181 gatgctatat tgtttgttgt gcctaccaag gtgactcggc ttgttgccaa gcaggtcgct
    27241 caggtcctag accacaaggc tattgtcatg cacgcctcaa agggattaga gcctggaacc
    27301 catgagcgcc tctcaacgat cctcgaagag gagatccctg cccagctgcg cagtgaggtc
    27361 gtggttgtgt ctgggcctag ccatgccgag gagaccatcg ttcgtgacat taccctaatc
    27421 actgcagcct caaaggacat cacagctgct aggtatgttc agaccctctt tagcaaccac
    27481 tacttccgtc tctacaccaa tactgatgtg atcggtgttg aaaccgctgg cgctctcaag
    27541 aacatcattg ctgttggagc cggtgctctg catggccttg gctatggtga caatgccaag
    27601 gctgctgtca tcacacgcgg tcttgcggaa atcacacgac taggggtcaa gcttggggca
    27661 gaccctctga cctatagcgg cctatctggt gttggtgatt tgattgtcac aggaacatct
    27721 gtgcattcac gcaactggcg agctggtgct gctcttggtc gcggcgaaaa gctcaaggac
    27781 atcgaaaaca atatgggcat ggtgattgaa ggcatttcca caaccaaggt agcctacgaa
    27841 attgcccaag agctaggggt ttatatgcca attaccagcg cgatttacaa atctatctat
    27901 gaaggtgctg acattaaaga aagcattctg ggcatgatgt caaatgaatt tcgctcagaa
    27961 aatgaatggc acacataagg aaccacaaat caaggaggaa ctcatgacaa aggtcagaaa
    28021 agccattatc cca
//
LOCUS       DARYXZ010000031        25999 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYXZ010000031 DARYXZ010000000
VERSION     DARYXZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25999
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(7..369)
                     /locus_tag="TV186_001205"
     CDS             complement(7..369)
                     /locus_tag="TV186_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1532602.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TV186_001206"
     CDS             complement(347..781)
                     /locus_tag="TV186_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1532603.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TV186_001207"
     CDS             complement(768..1058)
                     /locus_tag="TV186_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1532604.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TV186_001208"
     CDS             complement(1015..1440)
                     /locus_tag="TV186_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL1532605.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TV186_001209"
     CDS             complement(1418..1741)
                     /locus_tag="TV186_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1532606.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TV186_001210"
     CDS             complement(1742..2728)
                     /locus_tag="TV186_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL1532607.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TV186_001211"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TV186_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL1532608.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TV186_001212"
     CDS             complement(3829..4476)
                     /locus_tag="TV186_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532609.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TV186_001213"
     CDS             complement(4478..6481)
                     /locus_tag="TV186_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL1532610.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(7018..7383)
                     /locus_tag="TV186_001214"
     CDS             complement(7018..7383)
                     /locus_tag="TV186_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL1532611.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(7444..8490)
                     /locus_tag="TV186_001215"
     CDS             complement(7444..8490)
                     /locus_tag="TV186_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1532612.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
     gene            complement(9054..9608)
                     /locus_tag="TV186_001216"
     CDS             complement(9054..9608)
                     /locus_tag="TV186_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532613.1"
                     /translation="MRLKKLIYSSIAALAILTYGTISANADASIPEIDQTEVITILKS
                     DGYLNIDEGTQEVTITEKYKQAVLSSIDLDRQEAIFTENSVTIRDIFSPRSFTGVNKI
                     VFTWKGYDLYLDSTNANRLSALGWGSTALSGLIPDPIVSKVLAAALGVVSASISYANA
                     AGRGVIVAFVGTFPRGVIHWVASQ"
     gene            9877..10087
                     /locus_tag="TV186_001217"
                     /pseudo
     CDS             9877..10087
                     /locus_tag="TV186_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10179..13814)
                     /gene="rpoC"
                     /locus_tag="TV186_001218"
     CDS             complement(10179..13814)
                     /gene="rpoC"
                     /locus_tag="TV186_001218"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL1532614.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(13905..17471)
                     /gene="rpoB"
                     /locus_tag="TV186_001219"
     CDS             complement(13905..17471)
                     /gene="rpoB"
                     /locus_tag="TV186_001219"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1532615.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            complement(17733..20033)
                     /locus_tag="TV186_001220"
     CDS             complement(17733..20033)
                     /locus_tag="TV186_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1532616.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            20138..21394
                     /locus_tag="TV186_001221"
     CDS             20138..21394
                     /locus_tag="TV186_001221"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL1532617.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAHEDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            complement(21429..22238)
                     /locus_tag="TV186_001222"
     CDS             complement(21429..22238)
                     /locus_tag="TV186_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1532618.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(22231..22950)
                     /locus_tag="TV186_001223"
     CDS             complement(22231..22950)
                     /locus_tag="TV186_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1532619.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKPRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            complement(22953..23396)
                     /locus_tag="TV186_001224"
     CDS             complement(22953..23396)
                     /locus_tag="TV186_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL1532620.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            complement(23466..24317)
                     /locus_tag="TV186_001225"
     CDS             complement(23466..24317)
                     /locus_tag="TV186_001225"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL1532621.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            complement(24532..25056)
                     /locus_tag="TV186_001226"
     CDS             complement(24532..25056)
                     /locus_tag="TV186_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1532622.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            complement(25550..>25999)
                     /locus_tag="TV186_001227"
     CDS             complement(25550..>25999)
                     /locus_tag="TV186_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1532623.1"
                     /translation="QGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKG
                     EQGQRGEKGEQSQRGEKGEQGKDTKPSAPKAPEQSPAPQVPKTSEQQSASPKVPAPKS
                     APSKSAAPAAQKGILPATGETNHPFFTLAALGVIASAGLLTLKRKNN"
BASE COUNT         7809 a         6192 c         4886 g         7112 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta atccattttt ataaaaaaat aacattatat
     6841 catgcctcaa atgattttat cataatgagg ctcgctatgt tgttttctct atcccaatca
     6901 ggcactgcta gattagacat ctttccagac aacaaaaata gcctaaggtc agctctctaa
     6961 ttagctgatc ttaggctatt tgagtgataa tagatttgac tgatagctgt aagcctctca
     7021 gatgcttaat ttacagctaa gggaggcttg tgggcagtca tttctttgct caaaatatga
     7081 ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag agtgatactg
     7141 ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc aaaaggtagc
     7201 caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct gccattcttc
     7261 ctcaaaataa gccagtgcag caggccagct gtcaaacgat ttctcctgaa caatatcgtc
     7321 ttgccaacca tctataaacc accaaggctc ccagtctcca tacatttcaa tcacttgata
     7381 catgttctca tttcctctat tgcctattat agccgaagaa agatattttt aaaaaacatc
     7441 tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca gcagcataag
     7501 ggcctctgag caaagatgag tagctagcag ggtcatgaga aagaccagtt tcccttttgt
     7561 ggccggggca agctggtagg gccttagcag aaatagcgaa cattcgataa acattgggtg
     7621 caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt tagacagaag
     7681 gctgatacgg acactggcat tgaataaaaa ggtagtaaac agcgcagaaa gcaagaagaa
     7741 atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggcca ataagatcag
     7801 gcaaacagcc gcctttctca tatacctctg agaaaaaagc gacgatgaaa agtgatcata
     7861 gagcaagcag cccgcacaaa gataagcagg ggtgtaaaaa ataccattgc gacttgtttg
     7921 aaaaatgtgc atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta aaaaatgaga
     7981 ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg ttaccttctt
     8041 accaaaggtc ttcagagaaa gctgaacaag cacccacccc agccataaag caggaatata
     8101 ccacagatga tagcacatcc caaaataact aagggctaaa cacaagccaa ggggaagata
     8161 atgcttaggc agacgaagcg actcaaaaaa ggcataagca taagggaggt aaatcagaga
     8221 ccaaagcaaa taggttttta gtatttgctt gaagtactgc ttttcccgat tcgcctctct
     8281 aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg ccattcttcc
     8341 taaaaagctt ttcaaaaaga aatgcagcgg ctcatactga aacagcctac cgctatgaat
     8401 aacaataacc attatggcaa aacagtattg taacaggctt accacagagg tattgaggct
     8461 gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt aagagattaa
     8521 tatacgtata acttttagta tttatcgcat ttgtctctca ttttgattaa tattgttttt
     8581 atcatagcgt aatataacca attaatctaa tgattttagc ataacaaaag gagctaaggc
     8641 tagctcctga acatcacaaa agagcagacg aacttcatct cctctcgtgc ttagatataa
     8701 gccacccact acagttaaca tggagccata aaacgaagga attaactcct tcgttttctt
     8761 tcaatttttc ttggaatatt tttatagact tttcttacgg atatagtaag aataactacc
     8821 agcaataatg acataattca ataaaagaca taattaatca caacttgatt gtctttctaa
     8881 caaatccatt ccctgcctgg atcattagta tacgaaaaaa atgataggta aaactatacc
     8941 caataggcag aaaaaaactt tccaaaaaat agtattattt ttaaataatt tatcaacaaa
     9001 caccaataat atcaaattaa ttgctaaaca cagtattttt aaatataatg ctatcattgt
     9061 gaagccaccc aatgtatcac acctcttgga aaagttccta caaaggcaac aattactcct
     9121 cttcctgcag cattagcata agatattgat gcagacacaa ctcctaaagc ggctgcaagt
     9181 accttagata ctatagggtc tggaataaga cctgacaaag cagttgatcc ccagcctagt
     9241 gcagataatc tattcgcatt ggtactatct aaataaagat catagccttt ccaagtaaaa
     9301 acaattttat ttaccccagt aaatgatcta ggactaaata tatctcttat agtaacagaa
     9361 ttttcagtaa aaattgcttc ttgtctatct aaatcaatag aagataaaac tgcttgttta
     9421 tatttttctg ttatagtaac ttcttgagta ccttcatcaa tatttaaata cccatcagat
     9481 tttaaaatag ttattacttc agtttgatca atttctggaa tagaggcatc agcattagcc
     9541 gaaatagtac cgtaagttaa aattgcaagc gcagcgatac tagaataaat aagttttttt
     9601 agtctcataa tctactcctt tttaatctct aaaattaaaa caaacaatct ttaccggtaa
     9661 tagttaattt tactactaaa aataaactcc tttctggtaa aatgaaccac ctaagaaacc
     9721 tacatgtaca gaataacata tattttcctt aaaaataaga ctatatttta aaaaaacaaa
     9781 tgataaaatt aaattttgga agcttttttt ataataaaat aatttatcga tttttccact
     9841 attaagttat ttttgattaa catttttaaa atagttttgt ctatctacat acaatataaa
     9901 gactatatca ctaatgccat tgaactacct tattctaacg ccaagtttga agcgactagc
     9961 aaactgatca aagacatcaa gcgcaatgca tttggattca gaaacgttga caatttcaag
    10021 aaacttatct atgcttgctt tgaacatgac aaaagagaag acgaccttcg tctcctctcg
    10081 tgcttagtta tcagtcacct actatagttg acatggagcc caattaatct aatgatttta
    10141 gcatgataaa aggagctaag gctagctcct tttatttctt attccttaat aattgctggc
    10201 tcttctgtag cttcagcttc ttcgataacc tcaacctcat tgatagcttg cggttcaatg
    10261 ttacggtaac gaaccatacc agtacctgct ggaatgatct taccaatgat aacattttcc
    10321 ttaagcccca atagatggtc ttttttgcct cggatagcag cgtctgtcag cacgcgagtg
    10381 gtttcctgga aggaagctgc tgataggaat gagttagtct caagtgaggc ttttgtgatt
    10441 cccataagca ctggacgaga ggtcgcagga atacctccag agataacaat ctccttattg
    10501 gcatctgtaa agtctgcaat atccattaag gttcctggca gaagatctgt atcacctgga
    10561 tccatgacac gtaccttgcg aagcatttga cgaaccataa cctcaacgtg cttgtctccg
    10621 atttctaccc cttggctgcg gtaaaccttt tgaacctcag caagcaagta ggtctcaact
    10681 gacaaggtat cacgaacctc aaggaggtgc ttaggctgga ttgacccttc tgtaagggca
    10741 gctccacgat tgacctcatc accaacctca accttcatac gcgctgtaaa tggcacaaca
    10801 tattcaccca tgcctgtttt accttgaacg tagaccttct tagtacgagt tgatgcgtcc
    10861 tcttcaatct caataacagt ccccttaacc tctgtgataa ctgcttcccc tttagggttg
    10921 cgcgcttcaa agatttcttg gatacgagga agaccctgtg tgatatcggt attagaggca
    10981 acccctcctg tgtggaaggt acgcatggtc agctgagtac caggctcacc aatagattgg
    11041 gcagcgatag taccaacagc ctcaccaacc tcaaccgcat cacctgtcgc taggttgata
    11101 ccgtaacagt gacgacacac tccatgacga gtagcacagg taaatactga gcgaatggta
    11161 acctcttcaa caccagcatc aacaatcttg cgagccatgt cctcagtgat taattggtca
    11221 gcaccaatca atacctcacc agtttcaggg tgcttgactg atttacgagt gtatcgaccc
    11281 tgcaagcgct cctcaagtgt ttcagtgact tccttgccat ctgtgatagc tcgaataaga
    11341 aggcctcggt ctgtaccaca atcgtcctca cgaatgatga catcttgcgc aacatcaact
    11401 aaacgacgtg tcagatagcc tgagtcagct gtcttaagag ccgtatcagt cataccctta
    11461 cgagcaccat gagttgagaa gaacatttcc aaaacagaca agccttcgcg gaagttagac
    11521 aggataggaa gctccataat acggccatta ggagcagcca tcaagccacg cataccggca
    11581 agctgcgaga agttagagat gttaccacgc gctcctgagt ccatcatcat aacgattggg
    11641 ttcttaggat cctgtgtttc aatcagacgc ttctcaaggg cttcttttgc ctcgcgccat
    11701 gttgttgtga ctgcaacata gcgatcatca tcagtcatca agcctcgacg gaaggcctta
    11761 ttaatttcct caacacgatg gtgagcagcc tcgatgatct cagccttgtt gtcaataacc
    11821 ggaatatcag cgatcccaac cgtcaagccc gcaagggttg aatgatagta gccaaggtcc
    11881 ttcaagcggt caagaaaggc cgatgtttct gttgtacgga aacgcttgaa ggtttccgca
    11941 atgatgttac caagattttt cttcttgaag ggcacattga tcggtaagct atcaataacc
    12001 tcctgaatat tctgacctgg cttcaagaaa tatttatctg gagtgccctc tgtcaagtta
    12061 gcattatttg gctcttggag gtaaggaagg tcctctggca tgatgtcatt aaacaagatc
    12121 ttaccgaccg ttgtcaccat gattttgtgt ctttgactat ccttccaaag cttgcttggc
    12181 atactgtcaa cagcaatacc aacacgacta tgaaggtgaa catagccatt acggtaagcc
    12241 attaccgctt cgtccttgtc cttaaagacc ataccttcgc cttcacgacc agcatcttcc
    12301 attgttaggt agtagtttcc tagcaccata tcctgagaag gtgttacaac tggcttaccg
    12361 tccttagggt taagaatatg ctcagcagca agcatcaaca aacgagcctc tgcctgtgct
    12421 tcctctgaaa gcggcacgtg aatagccatt tggtctccgt caaagtcggc attgtaggcc
    12481 tcacacacaa gcgggtgaag acgaagagcc ttaccatcaa taagcaccgg ctcaaaggcc
    12541 tgaatcccta atctgtgaag ggtaggtgcg cggttaagca ggactggatg ctccttgata
    12601 acctcttcta gaatatccca gatacgctca tcgccacgct caaccatacg cttagctgct
    12661 ttgacgttgc cggcaaattc gcgggcaaca atctcacgta tcacaaatgg cttgaaaagc
    12721 tcaatagcca tctcacgtgg tacaccacat tggtacattt ttagcgttgg acccacagca
    12781 ataactgaac gacctgagaa gtcaacacgc ttcccaagca ggttttgacg aaaacgccct
    12841 tgttttcctt taagcatgtg gctcaaggat ttaagcggac gactaccagg tcctgtaata
    12901 ggacgaccac gacgaccatt atcaatcaaa gcatcaaccg cctcttgcag catacgcttt
    12961 tcattttgca caatgatacc aggcgcatta agctccaaca aacgtgctaa acgattatta
    13021 cggttaatga cacgacggta aaggtcattc aagtctgagg ctgcaaagcg gccaccgtcc
    13081 aattgcacca taggacgaag atctggtgga atgaccggca agatgttcag gatcatccat
    13141 tctggcttat tgcctgattt atgaaaggca tcaagcacat ctaaccgacg aacagccttg
    13201 atacgctttt ggcctgttgc tgtttttaat tcttccttta gctcagcaat ttctgtgacc
    13261 aaatcaacac gctttaggag gtcttgaata gcctctgccc ccattttagc aatgaatgag
    13321 ccatgtccat attcttggat tttttcacga tattcacgct ctgtcaatag tgattttggc
    13381 tcaagcggtg tgtcctttgg atcaataacc acataagccg caaaatagat tacctcctca
    13441 agagcacgag gactcatatc aagagtcaag cccatacgag atgggattcc cttaaaatac
    13501 cagatatgtg agacaggtgc cttcagctca atgtgtccca tgcgttcacg acgaaccttt
    13561 gcacgcgtta cctcgacccc acaacggtca cagacaatgc ccttatagcg aatacgttta
    13621 tatttgccac acgcacactc ccaatccttg gttggtccaa aaatgacttc gtcaaaaaga
    13681 ccctcacgtt ctggttttaa tgtacggtag ttgattgttt caggtttttt aacttcacca
    13741 taggaccatg aacggacctt acttggtgaa gctaatgtga tttgcatact tttaaaacga
    13801 tttacgtcaa ccactagttt tacctttctg cctttgatga cttactagca gctagggcaa
    13861 atagccctag tctagtcatt atttctgtta caaatgttta tgatttagtt gtcttcagtt
    13921 gattcagcaa tatcttgagt ttcctgagcc tgcttttcac gcgctttttc aagatcgtca
    13981 acgtgcatca cgtcatcgtc ttcgccttca tcaagatcac gaagctcaac ttcattatcg
    14041 tcttcatcaa ggacacgcat atcaagacca agtgattgca attctttcac aagaacgcgg
    14101 aaagattctg gtacaccagg ctttggaatt ggcttacctt tggtaatcgc ctcataagct
    14161 ttcaagcgac cattcacatc gtctgactta taggtcaaga tttcctgaag aacgtttgaa
    14221 gcaccataag cctcaagagc ccatacctcc atctcaccaa aacgttggcc accaaactga
    14281 gctttacctc caagcggctg ttgggtaacc agtgagtatg gtcctacaga acgcgcgtga
    14341 agcttatcat caaccatgtg gtgaagctta atcatataca tgacaccaac tgacacacga
    14401 ttatcaaacg gctcaccagt acggccatca taaagaacag tcttagcatc gctatccata
    14461 cctgcttcac gaacagtttc ccaaaggtcc tcagacgtag ctccgtcaaa gaccggtgtt
    14521 gcgatatgga tacccaaatt acgagcagcc atacctaggt gaagctccat aacctgtcca
    14581 atgttcatac gagacggcac cccaagaggg ttcagcatga tgtcaacagg ggttccgtct
    14641 ggcagatatg gcatatcctc aaccggtaca atacgtgaga cgacaccctt gttaccatga
    14701 cgcccggcca ttttatctcc gaccttgatt ttacgctttt gagcaatgta aacacgcacc
    14761 agcatattaa cacctgattg aagctcatca ccatttgcgc gtgtaaagat cttcacatca
    14821 cgtacaatcc cgtcaccacc atgaggaaca cgtaacgagg tatcacgaac ctcacgtgat
    14881 ttatcaccaa agatagcatg caggagacgt tcttcagcag aaaggtcttt ttcaccctta
    14941 ggagttacct taccaacaag aatatcgcct tccttgacct ctgcaccgat acggataata
    15001 cccatttcat caaggtcctt gagggcttct tcaccaacgt ttggcacttc acgtgtgatt
    15061 tcctcaggtc caagctttgt gtcgcgtgtt tctgattcaa actcctccaa gtgaacagag
    15121 gtataaacgt cctccttcac aagacgctca ctcatgataa ccgcgtcctc aaagttgtac
    15181 ccttcccagg tcatgtaagc aacgattgga ttttgaccaa gagccatctc acctttttcc
    15241 atagaagggc catcagcgat aaagtcaccc ttttcaacaa tatcacctat tttaacaagg
    15301 gttcgttggt tgtaggcagt accagagttt gaacggcgga attttgtgat gtggtaaaca
    15361 tcaagtgaac cgtcctcacg acgcacctct actctttcag catctgaaaa gacaacctta
    15421 ccattatgct gggcaattac cgcagcacct gaatcatgag ctgcttgata ttccataccc
    15481 gtaccaacat aaggagcctt tggatcaatc aatggcacag cctgacgctg catgttagct
    15541 cccattaggg cgcggttgga gtcatcgttt tcaaggaaag gaatacatgc tgtcgcaaca
    15601 gcgactacct gcttaggaga cacgtcaaca aagtcaacct gactagcagg aaactcttgg
    15661 ttattacctt ggtgacgtcc catgacaatc tcttcagcaa aggtaccgtc tggattgagc
    15721 ttagaattag cctgagccac tgtaaactca tcctcttcat cagcagttag ccaaacaatc
    15781 tcattagtca ctcggccaat cacacgatca accttacggt aaggggtttg aataaagccg
    15841 tatttgttca gatgtccaaa tgaagacagg ttattaatca aaccgatatt tggcccttca
    15901 ggtgtttcaa tcggacacat acgaccatag tgagtgtagt gcacgtcacg cacctcatag
    15961 ccagcacgat cacgtgtcaa accaccaggt cctaaggcag acaaacgacg tttgtgcgac
    16021 aactcagaca atgggttgtg ctgatccatg aactgtgata gctgtgaaga accaaagaat
    16081 tctttgacag ccgccgttac aggacgaatg ttaataatct gttgtggagt caacacatcg
    16141 ttatcctgta cagacatacg ctcgcggaca ttgcgctcca tacgagcaag accaatacgg
    16201 aattggttag caagcaattc accaactgca cggatacgac gattacctaa gtggtcaatg
    16261 tcatcgacct ttccaagacc ttcagcaagg ttaaggaaat aagacatctc agccaaaata
    16321 tcagccggag taagggcacg aaccttatca tctgggttag cattaccaac gatcgtcacc
    16381 acacgatcag gatcaactgg tgaaaccacc ttgaattttt gtaggatcac aggctctgtc
    16441 accaccgcat aatcgtttgg tgtgtagaca aacttgttca aatccccatc aagctgctct
    16501 tcgattgact caatcacact acgagtcatc tctgttccag cctcaaccag aatctctcca
    16561 gtctcactat ctattagatt ttcagcaata atttgattca aaagacgtgt cttgatgttc
    16621 agctttttat taatcttata acggccaact gctgccaagt cataacggcg agcatcaaag
    16681 aaacgagctg tcaaaaggct gcgtgagcta tcagctgtct ttggctcacc tggtcttaag
    16741 cgttcataaa tttccttaag agcctcatct gtacgtgaat cgctttggtt tttatgaata
    16801 tccttttcaa tggtattgcg aacaagctca ctatcaccaa aaatatcaat aatttcgtca
    16861 tcaccagaaa aaccaagtgc acgcactagc gttgtaaatg ggattttacg cgtacggtca
    16921 atacgagtat aagcaatatc ctttgagtca gtttctagct ctagccaagc accacgatta
    16981 gggataactg ttgagccata accaacctta ccatttttat caaccttgtc attgaaataa
    17041 acaccaggag accgaaccag ctgagaaaca ataatacgct ctccaccgtt gatgataaag
    17101 gttcccattt cagtcataat cggaaaatca ccaaaaaaga cctcttgtgt tttgatttcg
    17161 ccagtttcct tattaatcag gcggaaggtc acaaagattg gtgcagaata gcttgcatca
    17221 tggatacgag cctcttcaag ggtatattta ggctccttaa attcgtaacc aacaaactca
    17281 agctccatcg tgtctgtaaa gtttgagatt ggaagcacat cttcaaatac ttccttcaag
    17341 cctgaatcta agaaatcttg gaatgaatca gtttgaattt caatcaaatt tggtaaatca
    17401 agaacctctt tgattcttga aaaactacga cgggtacgat gtttcccgta ttgaacgtca
    17461 tgtcctgcca agtttttagc tcctttttct ttttaagctt tgctatcaag caaacaattg
    17521 caacatcaat atttgtctta agtggtattt ttagaatctt taaatttttg ttacaaaatt
    17581 gatttttatc taaaaatagg cacaaaaaga gcagctaaat cggaccttat cagtgtgatt
    17641 taactgctgt tctttctagc tggacaatat ttcagctaga ttagacgaca aatagttata
    17701 gatattatac actatttgtc tggaaaatac aactaatttc ttctaccact aaaacctccc
    17761 caggcttttt gatagtctgc gtctgttcca ccaatggcaa acctataggt agttgctccg
    17821 ggtccctttt gagcccaaag gctggttgtt agctctccac cgatggagat ggtttggcca
    17881 ttgatcgtca ctgtacccgg ctttagacca gtggccttca agacagaagc cttgataaca
    17941 ccaggatcca gtgaaaaccg ctgaccaagg ccaaaaagat tgggatcagc ctgactgatg
    18001 gcattaacca aataagccat ataatttgaa ttattattgt atcccgtcag tggtgcaagc
    18061 gaggtattgt catcatggcc tgcccaacca cccaaagtaa cccttggagt agctaagacc
    18121 agccagacat cggtataatt ttcggttgtt cctgttttac ctatccagtc agcacctgca
    18181 aggcttgggt tgatccctgc taatcggctt ttaaaagtgg ttgttgcccc agatgaaatc
    18241 ggccctctca agagctcctg taaaatcgtt gctgtcggag ctgagaaaat acgaaccggc
    18301 ttggcctcat gctgataaac aacggatcca tcactagctg tgatactagc caccatatat
    18361 tgcttttgat aaagaccatt attagcaatc atctgataag cattggtctg ctgggctacc
    18421 gaggtctcaa tcccaccacc aagtggcaga ctttcaatgg aataatcagc aatccgatat
    18481 cccattttac tcatatagtt ttcaacatca acgcccttat cacgcagcag cttttgagtc
    18541 caaaaggctg gaatattcca tgaggtatta agcgcctcct gcaggggcat cattgctgtt
    18601 ccttcactat cgacgtgcat gattttttga ccgctggaat aggtcgtcgg atagttggat
    18661 aggacactag cacttcccat taatccctga tcaatggcag gtccataagc aataatcggc
    18721 ttaatgctag agcctggaga gcgaacagta ttaaaggcat gattgttttg attttgagca
    18781 tagtctctcc caccaataaa gcccaaaaca gcacctgtag cattgtccgt taggacattg
    18841 cccatctgca ctgtcccagt gccatcatct aacaagccac caaactgagc tgccgctttt
    18901 tgcatcacct gatggattgg cttattgatt gttgttttga cagtgtagcc gccatgctgc
    18961 agctcagtta aggctcgctc ctcataggca gccttagtct catcattttt taaatcttta
    19021 gcaggcacct tatctcgctt aatcagatag ctatacatgg ccttttgtgc ctctgccaag
    19081 acagaatagt agaggtaatc atgagtattg gcagtgactg tttcaggttt gataaaatca
    19141 ttgctaatag gatatgcctt ataatcacga tattcttttt ctgtcagcac acctgttcga
    19201 tacatattgt agaggacatt ttgctggcgc ttaatcccat aggccatatc atcggctgat
    19261 tttaactgcc ctgtcggcaa atacggcgaa taaacaatcg ggctttgcgg aagccctgcc
    19321 aaaaaggccg cctgcggaac cgtcaaatcc ttggcagaga ctccaaaaat gccacgcgca
    19381 gcctcctcca cacctgcaat gttttgtccc ttattattac gaccaaaagg cgacacgttt
    19441 aaataatgtg ataaaatatc gtcctttgac atgtaacgct ctaaggccag tgcatagata
    19501 atttcctttg attttcgcct aaaggtcgga tcatcgccca agacttgctg cttaatcaac
    19561 tgctgtgtca gcgtagagcc accacttgac tccccaaagc ccaaaacaga ggccagagtc
    19621 gcacgaaaaa tcgcctttgg cacaatgcca ttatggcgct gaaagttgtc gtcctcagtt
    19681 gagacaatag cctttttgat attgtctgaa atcgcatcat tagcaaccgg tgtcctaagc
    19741 agatccgtat caatgcctga aatcaagcta ttatctgaat aggtaatctg tgacatcatg
    19801 gtcaatgatt caacctgctt gacaagactt tccttacttg gaatttttac cgagtcaatt
    19861 tgactggcta aatagccaaa ggccatacca gcacccagca tgccaaataa aaagacagct
    19921 acataaaaaa agctcgacat gaattttaat gtgcgcaaaa agaccgttcc aaaatcaact
    19981 aattctaatc gctgatgatt tttgcttgtt tgattctttt tccatttcac cataacgtac
    20041 ctcaatcttc attataccaa actttgatta agcttgcaca gccacagtca tttttgatat
    20101 aatgattcgg aaatcataaa gaaaatggag aaagcctatg aatatttttg aagaactcaa
    20161 agctcgtggc ttggtctttc agacgaccga tgaagaagcc cttgtcaaag cattaacaga
    20221 agggcaagta tcctattaca ctggctatga tccaacagct gatagcctgc atcttggtca
    20281 tctcgttgcc attttgacat cacgtcgctt gcagctagca ggacacaagc cctacgctct
    20341 tgtcggtggg gcaactgggc tgattggtga tccgtccttt aaagacgctg agcgtatcct
    20401 acaaaccaag gaaaccgttc ttgattggag ccaaaagatt aaagaacaac tctcttgctt
    20461 tcttgacttt gacaacggtg aaaacaaggc tgagcttgtc aacaactatg actggttctc
    20521 acagattagc tttattgact tccttcgtga tgtcggcaag cacttcacta tcaattacat
    20581 gatgagcaag gattcagtga aaaaacgtat cgaaaccgga atttcctaca ccgaatttgc
    20641 atatcaggtc atgcaaggct acgattttta cgagctaaat gctaagcaca atgtgacact
    20701 gcaaatcggc ggctctgacc agtggggtaa tatgacagca ggtaccgaat tgctccgcaa
    20761 aaaagctgac aagactggac atgtgatgac agtgccattg attacagatg caacaggtaa
    20821 aaaattcggc aagtcagagg gtaatgcgat ttggcttgac gctaaaaaaa catctcctta
    20881 cgagatgtac cagttctggt taaatgttat ggacgatgat gcggtacgct tcctgaagat
    20941 cttcaccttc ttatcacttg atgagattgc tgctattgag gagcagttca acgcagcacg
    21001 ccatgagcgc cttgctcaaa agacacttgc gcgtgaggtg gtgacactgg ttcatggaga
    21061 ggcagcctac cagcaagccc tcaatattac cgaacagctt tttgcaggag ctatcaaaaa
    21121 cctttcagca gctgagctta agcaaggctt aagcaatgtc cctaactatc aggttcaagc
    21181 agaagacagc ctaaatatcg tggatatgtt agtcacagca ggcatttcac catcaaaacg
    21241 tcaggcgcat gaggatttac aaaatggcgc gatctacctc aatggagaac gacttcagga
    21301 tctggattac agcttatcta cagcagatcg cattgacaat cagttgaccg tcattcgccg
    21361 cggcaagaaa aaatacgctg tactaaccta ctaatcacag acagctagga aaatcttgct
    21421 ttggatgatt atttttgacg tataaaggac agcaggttaa ccacaaggaa gatcgcaata
    21481 aaaatcatcg taatggtcgc acttgccggc gtttcccaaa aataggacaa gaaaatacca
    21541 gacagcatgc ctgtaaagcc aatcataatc ccaagaaaaa taactgattt aaagtttttc
    21601 ccaagccgca tagcaatact tgctggcaaa accataatcg ttgataccaa aagggcccct
    21661 gccgctggga tcgttagagc aatagcaaca cctgtcacaa tattaaacaa gacagacatg
    21721 acacgcaccg gcaagccatc gacgtaggct gtgtcctcat cgaaggtcaa gatatacatt
    21781 ggacgaataa ataatatcgt caaggctaaa ataatcaaag caatgacaaa taaggcagca
    21841 acctgctccg tactaatagt aatgatagag ccaaaaaggt attgctccaa gctcatacta
    21901 gaagagctag ttgacttact catgataatc aaggaaatag ccagccccaa ggacattagg
    21961 atagctgtcg aaatctccat atagtgctta taaaccaccc taagatattc tagcaagatg
    22021 gcagctagca ccaccacaat aatcgttgtg aaggttggcg aaacaccaag aacaacacca
    22081 aaggccacac cagccagaga aacgtggcta agcgtatcac tcaacaagct ttgacgacgc
    22141 aaaatcaaaa agatacccaa aatcggagca aagatactga tcgccacaac agccataaca
    22201 gcacgctgca taaaatcata agataaaatc tcaagcatgg aatgaccctc ctttgctctc
    22261 atcagcctca gcatcatgaa tgttgaagca acgccaagga agccgttgat ttctaatcaa
    22321 atgaatattg cgatcagcat aagccttgac ctcctctggg tcatgtgtaa tcatcaaaac
    22381 agccttacca tgtctatgag cgctgtggtg catcaactca taaaaagtat ctgttgttcc
    22441 actatccatt cctgtggtcg gctcatcaag cacaaaaata tcggggtcag aagcaaacat
    22501 acgcgcaata accacacgct gcttttgacc acctgataga ctccctattc tcttatgccg
    22561 actatcccac atgccaacag actccaagct tgtccgaaca tgctcctcat cgtgcttact
    22621 tagtctggta aaccaaccac ttctaggata tctgcctgat ttaacaaatt cataaacagt
    22681 cgacggaaag cctgcattaa agctggcaac ctgctgtggc aagtaagcaa ttctcagctt
    22741 tttcccatga atgttctgtt tagctatagt cacctgccca gcccttggct ttaaaatccc
    22801 caaggtcgcc ttgatcaggg ttgacttggc agcaccattt tcaccagtca atgtgacaaa
    22861 ttctccacta tccaaatgat agctgattcc ctctaaaaca ggctcactgt catactggaa
    22921 cgagagattt tccaccgata tgtatctcat tattaccctt ctaactcctc cgcaaaagca
    22981 gtgataaatt tttcaacaat cacctgctcc tccgcagaaa aatgtgccaa caaacgatga
    23041 taaacagcta gtgttttatc gtgatgatgt gtatgctcct tagcgattgg ccttgctaga
    23101 tcagtcagtt caaaataggt tactcgagca tcaacggtat cctttgttcc tgctagcatt
    23161 tcttgcttga tcaagccttt aatcgcttta gttactgctg cttgactgat atttagcctt
    23221 tttgccaaat ctgtattggt tagcttttcc tgtgacaaaa gcatcaaaat atgctcctga
    23281 gtatttgtta atttgacatc actctgacaa gccccaaaga gcagctcatg ctgattttca
    23341 gcctttaaca aaatacgatt aaccaaatta tcaagctttt tttctaaaat tgtcatgatt
    23401 tccctctcct cattaaccag ttaattataa catgacgccc caaaagacgc aacttcaagg
    23461 ctgatctaca gcgttctaac cttgtagact tccttacaaa agcctttcag gctattcacc
    23521 acacgattgg cctgcttttc tgtttgacat agggcaaata ccgttggacc acttcctgtc
    23581 atcagggcaa tgtctgctcc tgactgcagc attttatcct taaccttttg aataaacggc
    23641 cgtttagcaa tggaaatatc ctctaaggaa tttcccatcg ttgcaagcaa gcgctgataa
    23701 tcacctgcct caatggctga aaccagatcc tcaatcggca ctcgagatat cgtctcacaa
    23761 tcaatatccc aaaaaatcgt tctagtagaa atgccaaatt ctggcttcac tagaaccacc
    23821 caagaggaca agcggccatt gattggctta accacctcgc ctttgccagt cacttgggcg
    23881 cagcctgcaa aaagacaata aggcacatcg ctaccaatct gcatgccaat gtcaatcatc
    23941 tgacggggac taagctttag ctgccacagc tgattcaatg ctctgattgc tgcagccgca
    24001 tcacttgagc cacctcccat accagcacaa acaggtaccc tcttatccaa gaaaatagag
    24061 acacctgttg agatttgaaa tcgctctttc agcaaataag ccgccttgta aacgtcattg
    24121 tgctcattaa taggcaatct agggcaatta gaggtcaata aaatcctatc ctcctctaaa
    24181 tgatccactg taatataatc acaaagatct acactaacta gaaccataga taggtcatga
    24241 tagccatctg gtcgcttgcc ttgaatatct aagcctagat ttatttttgc aggagctctc
    24301 tcaatgattg cagtcataat actcctttat ttgatgtcat tatagtatca aatatacaca
    24361 atcttcatga aaaattcaaa taaatacagt tagtatctaa tgatgcatag acagcgtgtt
    24421 tgtatcaaaa cagccaacca tttgtcccta ctagcgtgag gcttcaccag atcagcagcc
    24481 aaaaaacgac aactactagc atagcaagca aagctaagac agcagcagtc tctatgacca
    24541 cttgatcgct ccatattgcc ccactaactc aaagcacata tcaatcttgc tcttaaagta
    24601 gggaataaaa ataccagcat caatcatggc taaaatctca tcacgactag cccatcgaac
    24661 agcctgtacc tcctctgtct gaagaactag cttccttaca tcaacagcct gcaaaatcaa
    24721 aaaagtatcg tcaaagccat tatcaaaggt aattgaaaaa tgaggcctta caccagctaa
    24781 atcaagagta agtcctagct cctccttcag ttctctcatc actgcctctt gtgacgtctc
    24841 acctgcaaga gcgctgccgc ctaccgttat atcccaatag ctgggccaac cctctttatc
    24901 cttttgccgc tgctgaatca gcatttctcc cttgtcatta aagacacagg cgtgaaccac
    24961 taaatgataa gcaccctcta caaaagcagc tccacgctcc atgagtctac cagtcttaag
    25021 acgattcatc gtataaatgt cccaatactc aaccatacaa acacacctcc tgatacagct
    25081 attaccagat ccagtatatt aatcatatca caataagcat atccaaaaca accaggtcca
    25141 gacaaaacaa caattaccaa cctagcttaa ttcttttttc tacaattccc taccttaaaa
    25201 tgcctcgcat agaaaatgga caaaaagatc tgttttcccg agacgtatca aaaagctcac
    25261 cacgctaaca aactggtagt taagatcccc aagcgtctta ctcagttaac gatatggtga
    25321 tacacacagc tgacttgcct catcatatta gttacaaaaa accttaaagg ctcaacccaa
    25381 aagcacacca actacatcac cccatgaaag aggaagacaa aacatctact gctgcaagca
    25441 aaaagagacc ccattagggc ctctctagtg ctcatatcag cttttaaact aatcaatcgc
    25501 cttcaagcta aaggctatca tttagtagga gaaagttgca aaagctaatt tagttgtttt
    25561 ttctttttag agttagcagg cctgcgctgg caatgacgcc gagagctgca agggtgaaga
    25621 atgggtgatt tgtctctcct gtagctggta atataccctt ttgagctgct ggagccgctg
    25681 atttgcttgg tgctgactta ggcgctggta ccttaggact agctgactgc tgctctgaag
    25741 tctttggtac ctgtggagca ggagattgct ccggggcctt tggagctgat ggtttggtat
    25801 cctttccttg ctcgcccttt tcaccgcgtt ggctttgttc acctttttca ccgcgttggc
    25861 cttgttcacc tttttcgcca cgttggcctt gctcgccttt ttcgccacgt tggccttgct
    25921 cgcccttttc accgcgttgg ccttgttcac ctttttcgcc acgttggcct tgctcgccct
    25981 tttcgccacg ttggccttg
//
LOCUS       DARYXZ010000032        25264 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYXZ010000032 DARYXZ010000000
VERSION     DARYXZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25264
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            162..377
                     /locus_tag="TV186_001228"
     CDS             162..377
                     /locus_tag="TV186_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1532624.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            377..1240
                     /locus_tag="TV186_001229"
     CDS             377..1240
                     /locus_tag="TV186_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532625.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1313..1807
                     /locus_tag="TV186_001230"
     CDS             1313..1807
                     /locus_tag="TV186_001230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1532626.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            1811..2221
                     /locus_tag="TV186_001231"
     CDS             1811..2221
                     /locus_tag="TV186_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1532627.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            2181..4658
                     /locus_tag="TV186_001232"
     CDS             2181..4658
                     /locus_tag="TV186_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL1532628.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            4660..5685
                     /locus_tag="TV186_001233"
     CDS             4660..5685
                     /locus_tag="TV186_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1532629.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            5651..7939
                     /locus_tag="TV186_001234"
     CDS             5651..7939
                     /locus_tag="TV186_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1532630.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSKVSYRTLTDDEKYDNNQN
                     DKGKNYNDYVKNPKSKNKRYKNYVKDTFSKERMKSENQKKYVRSNFDDEEFTRNKDTK
                     NNLFQDVNNKRKTTDKNSSRKRKGKFENKEKKISKLQQKKQRQEQKLKNKGIDGKSQS
                     AKSAVIATGMAKRYLESGKEDNAGVGTAYKVTDQVENISRKIYYHGKKKNLKRQKKIT
                     KLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQFFKRRQYKNQIQKKYKDSVKNR
                     IKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFMLFQAGSMMMNMGTGMVSNTVST
                     TYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGYDEYIIKGKEKIGHNVHELLSY
                     ITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIRYRTVTSSYTDADGNEHTESHE
                     EPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYETLFLTQGNMGEVFGNIDLINSN
                     GGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGFIGGNACDMY
                     RNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVGIYIGDGKVMDNIGHIRVTTLD
                     DWIATFCKHHPVGFGFPPSVQK"
     gene            7952..8239
                     /locus_tag="TV186_001235"
     CDS             7952..8239
                     /locus_tag="TV186_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1532631.1"
                     /translation="MNKKYRKNIEKQKDIQKKIEELQLKQEMLKEEQEEMENIEVLKE
                     YRSIDISIDDFLEMMRRYKKEEKQEKMKLQEMRNTENHNNMEENHENQMEE"
     gene            8244..9680
                     /locus_tag="TV186_001236"
     CDS             8244..9680
                     /locus_tag="TV186_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1532632.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            9933..10526
                     /locus_tag="TV186_001237"
     CDS             9933..10526
                     /locus_tag="TV186_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL1532633.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     IQSYSSYKERDIHSLYDIAMKMGIENKVREVMEVAYE"
     gene            10519..11361
                     /locus_tag="TV186_001238"
     CDS             10519..11361
                     /locus_tag="TV186_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1532634.1"
                     /translation="MNKAKLTALCHKVSKEVGLSFNAVMLYYFLESILKKLAGSKYSE
                     RFIFKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYEL
                     QNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEI
                     IIKAYPIETMLAEKIQTIYARGFLNSRSKDYYDLYIIYKLKDKDVNVEILREACRKTF
                     SYRKTEFDIGKIIDLLEKLKINEAFLKRWQAYSRKNLYAKDITFEEVLDNGIKMVEKI
                     KNEN"
     gene            11533..13245
                     /locus_tag="TV186_001239"
     CDS             11533..13245
                     /locus_tag="TV186_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL1532635.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            13249..13800
                     /locus_tag="TV186_001240"
     CDS             13249..13800
                     /locus_tag="TV186_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1532636.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            13842..14588
                     /locus_tag="TV186_001241"
     CDS             13842..14588
                     /locus_tag="TV186_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1532637.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            14605..>25264
                     /locus_tag="TV186_001242"
     CDS             14605..>25264
                     /locus_tag="TV186_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1532638.1"
                     /translation="MNDLIKNYENIPDEMKKEKRWCLYKIIQRDGKNTKLPLMPNKEP
                     AKSNDKATWNSYEDCIMALKHNVGEGLGFFLGDGYIGIDIDKVSDDIMEYNTNHHVSS
                     MTADFLREVSTYAEISPSKTGLHFIGKGEVPGERKRYKNLEIYDKDRFFTVTGNVIKD
                     RDRSKIESIDSELKPLYEKYMPKTNKISAENKRSPTVTSYNGDQDILEKLFDRGYFSY
                     AGEDLRQIYYGNYERYFNSQSEADFFMLQRLLYYTGNVEMAISFMESSGLKREKWYKR
                     RGNTDYIHYIADKAISSINQFYDWEKVYTSKEKIEEKRYENKKKKEGDTVPRYEFDEV
                     KQILDFAKEEFKENIDRYETYLKVMGNNYKYPYFNQLSIYTVNENATACAEYDYWKSI
                     GRNVNRGEKGIPVLDIEREKIKYIFDASQTVSLNHNISEVKLWEYSNNKHVAALDTLI
                     DVFKEKNSNLIFSTEDKINTIVSLYTKQLLNKVLNSLSDETLKENKKVQILHFLEESA
                     KVSVYERMGVAFSGDIEKLEMLSNVSSMQDIDRLLFFTSNNVKRILMDISREISKVEE
                     REKISEIQKREQTNSIAERYTNVTDEINGNTEIIENEKERNEGGLEDERNRSIGEEGV
                     HPRKRDLYTDRKRESIRETGRDLQIGENGGWSGSISSEYENAGENKRKQTEPIWQGET
                     EISQRGETRGISDYADGRNFNGSFDRYSGTSGGFPEYRRAEDERSLENDHRNAGSGLS
                     EIHRTEEELGYDTNKNGYGTDHLGIDEYRKENIQKIEQNHVENEEKEVERTSFSFAQN
                     VGVQGRFELPMQQEEIGAVLIHGGNEDNLHLKVLAEYSKEKSMEELADFLQKTFQGGN
                     GYELNGNKVCAWYEMDGIHLSNDVSSRENPMQILPWKDAAIRIGELIDYGKYSTNVEV
                     AEAFSFERAELSEKLWFLKGDLSDEVKNQFLPILNEKQRNGYPEKTEYLTKKLEDKEF
                     RVNLKEEYIEFFKAYKENSNVLRFHNHDLDDISKRLDDLELPRKEFTSTLIELPAIQG
                     FITEDEIDRYLSSGSNVSGGKERIYNFFREAHTTEERANFLKDEYGTGGQTHALSRAR
                     GSSEWHDAKGIKLEKENCKDIILKWNQVVKKIDNLIENGKYIQEDVYTEQESIKTEEE
                     YFDEDTYTEQNSKENEQDWQREQEILLIQDEREVSYEEAEEIYERQAEIEHNAFATGV
                     ENNISSTQSNKDYWIVEFNEGSNLIEKNYAGEVVTKKLLDEIKVLDEKIRVHNKTVGE
                     DEYGEMTDEWVGYSKFYFDHIVDGKVEEHFRMDIGDGNEVNQRDFQYLYEQIEPEKEN
                     KEYGMDSIDSVIKDILEKESMTVVSSKDDYIKLFPYFRNFVYTDGLRLDEYNPFEDDE
                     NISDLIRLTFFQNNDGEYRVVYNNADSLLYSSNVDYFLEKIEAEKVRLEDNIAEIPNE
                     DKIAVKVGNYYAVVEKERVKDISLEETGVRVYPKENNFEGKIYPLYRGSTFEESAKID
                     KLFDEIAIGMKEVNLTDLNDVFYLENQGLYEISSDRVTEEKAGYDFEVASFNEQFPDY
                     YNDIYVYNRNLKIDGANQNIAYINRENEIHFNVNLPEEEKAKVLEIRDKKEVLSTLIF
                     KDVKEVGEYQFHPQSEEFILNELSISEEKLKAPEHITDKIDKKEGYEAELVLDMKNKE
                     LRQHLRYNGYMLSSNVAVSYDSYKAILKNLSYLLDDNHRNIMLTGYVNEQIEKDKAKE
                     ERKEPVYQEGMNVRYQGKEYIISEIQDYKTYKTIKLDDSEGYLNGFITGSEIIPFRNE
                     RELDLEIISTTEKLQEQSINGEDLILLDIEEYNKKGLSVIFQNKEYEITGNNFNPVGM
                     SRLQLVSNTEKLMTEISYTPQRPVANLYAKKDLLERFNLNEKNSEKSIEAKQMSLTDI
                     FEEQDTTKGKEEISSEKERVPVNIGAKVIYQGEEYTVSAFEYNNILEKNDIWLNPVSK
                     NNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSELLHHSLDVINDKGSVIANQFIVK
                     VDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQIDGDGNNLKLTKHKKETIDKKLKS
                     YHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEYEEKLKEEERYAPDDKYLGGIPP
                     INYKITKEDEILPPSERLKNNIEAIKVLKEIEERHSHATKEEQDILSRYVGWGGLSDV
                     FDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAFYTPKIVIDSIYQAVLNMGFESG
                     NILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGRIASRLYPNAKIQIKGFEETTFS
                     NNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFAKTLDKVRSGGVVAFISSSGTMD
                     KKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVTSDIIFLKKRDRLVKLDEEWVKL
                     GTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLACVADENSTLKEQLDTAIKNIKG
                     SYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYFRENSVMQKLNLNKNDEEKVRAY
                     LGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDEFSKKYGILNSKANKKLFREDAN
                     YSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHTDNLTEALILSISQKGKVNFEY
                     MEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSSAIDLGDFSRSYVTADEYLSGN
                     IRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQGSETLKKELSSLNYQRQKLLEVM
                     PKELEASEITVRMGATWIPEKDYKSFMFHLLKTSASNRWNIDIKYTNFTGEYRVEGKS
                     IDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYDQVIDENGKKSSVLNQKETMLAR
                     SKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIRLREYDGSNLTFDGMNPEIELRP
                     HQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHIVEQFG
                     REFNELYPAANILCATEKDFTPDKRKRFCSRIATGDYDAVIIGHSQFEKIPISKQRQE
                     YELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKGLEAKLKKLNDDYRKDDVVTFEE
                     LGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQKSSDMLMKCRYMDEITGNKGIVF
                     ATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSWASTFGETVTAIELNPEGNGYRS
                     KTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNAHYETIKTKPTEEQKQILETFSE
                     RADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINPLLPDDPNSKVNTCVNNIFSIWD
                     KYRDEKSTQLVFCDMSTPSSEFNIYDDIKEKLTKMGIPKNETEFIHNAKNNKEKDKIF
                     DKVRKGEIRVLLGSTQKMGAGTNAQNKLIATHDLDVPWRPADLEQRKGRIVRQGNEND
                     DVHIFRYITENTFDAYLFQTLETKQTYISQIMNSKTPVRVAEDIDEATLNYAEIKALA
                     TGNPLIREKMDLDVEVSKLKMLESNFKSN"
BASE COUNT        10144 a         3137 c         5253 g         6730 t
ORIGIN      
        1 aaaagagaga tgggataaat aaaatgaaaa atataataaa atcaataagg ataagaagtc
       61 caactttaag aaaattgaat agcaaaagtt taacgattgg aagagaagat ttccagtcgt
      121 ttttttatga aaataagtaa aataatgagg aggaataaat tatggatttt tttgtacagg
      181 cagtaaatgt gcttaaaatt ttggttatgg caatcggtgc aggacttggt gcatggggag
      241 ttatcaactt acttgaagga tacggatcag ataatcccgg tgccaagtcg caaggaatca
      301 agcaattgat gagcggtgga ggaattgttt taatagggct gaaactaatt ccgctacttg
      361 ctaatgtctt gagataatgt ttgatttatt tggaaagata gaagagtttt tcaaggatat
      421 tatgattgat attattaaag ataatctttc tgcaatgctt gtggatatta atgataaagt
      481 aggaaccgtt gcaggagaag tgggaaagac tccgagttct tggaactcgg aggtcttcac
      541 cttcattaaa tcaatcaata ccaatgttgt tttacccata gcagcgataa ttctaaccgc
      601 aatactttgc atagaactga ttcaggtggt aatgagaaaa aattctatgc acgatacgga
      661 tacctttgaa ttttttaagt acattattaa aatgtggata gctgtatggc ttgtgtctca
      721 tgcgtttgat ttttcaatgg cagtctttga tgtggcacag tccatgatag gaaaggcagc
      781 aggtgttgtg gggacaagtg cgaatatcac accgggaaat tttgatgcta tggtagaagc
      841 ccttaaaaca aaggaacttg gaacactcat tgggattgca ctggagacgg gattagttaa
      901 attttcttta acgattctat caatcttaat cactgtaatc ctatatggaa gaatgattga
      961 gatatatatc tattgctctg ttgcggcaat tccattttct acgatgggaa ataaagaatg
     1021 gtcaaatatc ggaacaaact atataaaaag tctatttgcc cttggacttc agggactttt
     1081 catcctaata ttttttggaa tttacgcagt cttagtcaaa accgtaaact ttacggatat
     1141 ccacacaagt attttacagg tattggcata tggattgatt cttggagtaa tgatgatgaa
     1201 atccggaagt atagcaaagg cgattttaaa cagtcactaa aggactttag ttcaaaatga
     1261 gcaaaagttg atgaaataat cagaacaaaa aatataatta ttggaggtaa gaatgaataa
     1321 aataaataaa aaaacaagga ttttgatagg agcaggctca gccctttcta tcgggacaat
     1381 tattacagtg ctattaaaaa agaaaacgaa aaaattatcc gatcttgaag aagatgattt
     1441 tgactttgat tttgatgaaa tagaagaaga ttcttgtgtc aacgataaat ttgctacaga
     1501 aaatgataaa gatgatacag taaaaggaga aatagatttt ttagtagatg aatcaaagac
     1561 ggagaacgaa aagcaagaag agtttagaga tttatcggta aaggtaatgg atcttcttct
     1621 aaaagaagta atttcaatga gtgaaacctt aaatttggta aaaagagata ttgatagaat
     1681 aggtgaagta aaagcattgg ttgaagaact ggaaaactgt aaagaagaaa ttatctcact
     1741 ttgggagcac atggaaaagt tatccgattt aagagaagaa attaccggca aaaagaatag
     1801 aggttaggct atggcttatg taaagatacc aaaagacctt acaaaagtaa aaaccaaggt
     1861 agccctgaat atgacaaaaa ggcagcttat aggttttagc atagcagggc ttatcggttt
     1921 tcctgtatat atgctgtgta aaaattttct tagtacagat atttccatga ttataatgag
     1981 tatagtagtt ctacctgttc tttttgtaac gctttatgaa aaggacaatt taccttttga
     2041 aaaacattta gcatatatcc tcaggtttca taaaagtaaa aagatcaggc tatataaagc
     2101 gaggagcatt tatcatacag agagagcaaa aaagcaagat ataggaaata aaaataaggc
     2161 aagcggaagg aggaaaaaag ttgaacaaag acaaaagaaa aaaacaggaa caacgaatta
     2221 aaaaggatga gttggagctt aggaaaaata gaaaggagct atccgaactt aaaaaaacag
     2281 gaaagaaaaa aacaaagtct aaaacaaaag ggaaatcatc gaagaagaat gggtggtttc
     2341 ctttttttat gaaagaggag aaaaaagaaa ccgtacagga taccattcca tataagcgaa
     2401 tgttaaaaga cgggatttgt caaattgaaa agaataagtt taataaaacc attcgatttt
     2461 tggacattaa ctatcgctta atggaagaaa tagaccaaga gggaatattt tcggaatttt
     2521 cttcttttct aaatttcttt gactcatctg tggaagtgga gttcagctat atcaacagta
     2581 tcggagaaaa tgaagaaatc aataaactga ttgatattaa ggaaaatata gatgatttta
     2641 atgaaattag aaacgaatat agacaaatgc tcttaaatca aagcagcaaa gggaataatg
     2701 gattatcaaa gagtatgtac attaccttta ccatagaggc ggaggactta aagcaggcaa
     2761 aaagtagatt agagcgaatg gaaatggatg tattaaacaa ctttaagcag atgggagtga
     2821 aagcctatgt gttagatgga gaggaaagac ttaaaacaat tcatgacatt ttaaatccaa
     2881 atgataaact tgttttttcc tttgaggatt tgaaatacag cggactgacg actaaggaat
     2941 acattgtacc tccgtctttt aacttttcca agccgacgta ttttaagaca ggagaagtct
     3001 ttgcggaagt aaatttttta cagcttttag catcagatat taaagatgag atgttatcag
     3061 agtttttggc attggaagaa aatatgattg ttacttttca tatcagagca atcgaccaga
     3121 tggaagctat taaacatgta aaaagaaaaa taacggattt ggataagatg aagcttgagg
     3181 aaaacaaaaa agctattcgt gcgggatatg atatggatat cttgccaagc gaccttgtaa
     3241 cttatggtgc agaggcaaag aacttgctat cagaactaca aaaccatgat gaaaagatgt
     3301 ttctcataac aattttattt atgaacacga gtaaaagtaa ggggaaactc gataatacgg
     3361 tatttacctt aaagtccatt gcaaatagac ataattgtag tttgaaaaac ctaaattata
     3421 gacaagaaca agggcttgtt gcaagccttc cacttgggat aaatgaagtg gagatagaac
     3481 gaggacttac cacaagtgca gcagctattt ttataccatt tacaacagaa gaactcttta
     3541 tcaagggaga aagcctatat tacggactaa atgcactaag cagaaatatt attatggcgg
     3601 acaggaagaa attaaagaac ccaaatggtc taatcttagg aacaccgggt tctggaaagt
     3661 cctttgcagc caaaagagag attactaatg cgtttttgat tacagatgat gatattatca
     3721 ttgcagatcc ggaagcggaa tattctccgc ttgtagaggc actaaaagga caagttatca
     3781 gaatttctcc gatttcaaaa gactatgtca atccactgga catcaatatt gactatgcgg
     3841 atgaagataa tcctttgtct ttaaaatccg actttatttt gtccctattt gaattggtgg
     3901 ttggagaaaa gaaattaagt gcagaagaaa tttctgttat agaccgttgt ttaccaattt
     3961 tatataaaac ctactttgaa aatcctgtgc cggaaaatat gccaatttta gaggatttat
     4021 ataatcttct tcaaaaacag gaagaaatag taggaaaaaa gcttgcagta gaaatggaga
     4081 tctatgtaaa aggaagtctt aatgtattta atcatagaac gaatgtagat acaaataaca
     4141 gagtggtttg ctatgacatc aaagaactgg gaaaacagct taaaaagata ggaatgttag
     4201 ttgtgcagga tcaagtttgg aatagagtta caattaacag agcaagtaaa aaagcaacca
     4261 gatattatgt tgatgaattt catcttttgt tgaaagaacc gcaaacagcc aattattcga
     4321 ttgaaatctg gaagcgtttc agaaaatggg gtggtatgcc aacaggactt actcaaaata
     4381 tcaaagacct tcttgcaagc ccggagattg aaaatatttt tgataatacg gattttattt
     4441 taatgcttaa tcaagcagga acagataggg atattttagc caagaagctc aatatctcca
     4501 agcatcagct ttcttatgta acaaattcgg gggaaggaga aggacttatc ttttatggaa
     4561 atacgattgt tccttttatc gatcagtttc caaaaaatac aaaactatat tcactaatca
     4621 caaccaaacc tgaagaagta aaaaaggcag gtgaatagga tgagtgtgag cagaagtaaa
     4681 gaggaattca tcaaagaaaa tacaaataaa attatttgtt cggatgcact tgaaacttta
     4741 agaaaaattc cagacgaaag tataagctgc tgcattacat ctcccccata ctacaggctc
     4801 agaaactatc ataaagaagg tcagatagga agagaatcta cagtagaaga atacttggat
     4861 agattgttac aggtatttcg tgaagtaaga agagctttaa aaaaagaagg tacttgcttt
     4921 atcgtaattg gagattctta tgctgattca ggaggtggaa agggacaata cattgatcct
     4981 aaatatccaa aggcaagaaa tggaagtaac gctttagcta cagaaaatat ctcagggtac
     5041 aagtcaaaag atttaatggg aataccttgg agattagcgt tacttctaag agaggatggt
     5101 tggtatctgc gttctgatat tatctggcat aaggaaaatg ctatgccgga ggcgtgtaga
     5161 gatagaccta ctcgttccta tgaacatatt tttttactta cgaaatcacc aaaatactat
     5221 tatgactatg atgctatggt agagccgatg aaagaagtca gtaaaaaaag atatgtaaga
     5281 ggaagaaaat cggataataa atatctgaaa gaaaattccg gagcaaagtt gcaaaaaatc
     5341 aatgaagcaa gaaaatatgg agaatataag ggcgataatg tcccgcagtt tcgtaataaa
     5401 agagatattt ggactatcaa taccacatct tttagaggca atcattatgc aacatttcca
     5461 ccgaaacttg ttgagatttg tatgattgca ggttgtccta aaaatgaaat tgtacttgat
     5521 cctttcattg gaagtggaac ggtcggattt gtggcacttc gtcataacag aaagtacatt
     5581 ggaattgaat taaatgagga gtatgtaaat cttgcaaaga atagaatcag tgaggaggtg
     5641 aaaaaattta atgaagaaca aaaacaagag gtacaaaaag aatagagaaa aactcttaaa
     5701 tcaagaaata cagtctttac aatctcaaac tcaagataat tatgaaacag gatcctcaaa
     5761 aaatcagaat gaaaccttgc tgaaagacga aacttacgat aagaaacaat ttttatctga
     5821 aaagaagtta tccaatcatt tggataatag acatataaat aattattcgg atagaactat
     5881 atcttcttat tgcttgtcgg atacgggaaa tataaatcaa aataggtctt cctttcaagc
     5941 tgaaaaacat aaaaaaaaga tgcaaaagca gataaataaa tttcaaaagg gagaaaagga
     6001 agtctacgat cctttatcaa aagatatgga taatgatggt gtaatagaca ggtatgatgt
     6061 ggattttagg gatagcaaag tatcatatcg aactcttaca gatgatgaaa agtatgataa
     6121 taaccaaaat gataaaggaa aaaattataa tgactatgta aaaaatccaa aatctaagaa
     6181 taagaggtat aaaaattatg taaaagacac attttctaag gaaagaatga aatcagaaaa
     6241 ccagaagaaa tatgtgagga gcaactttga tgatgaagag ttcacaagaa ataaggatac
     6301 gaaaaataat ttatttcagg acgtaaataa taaaagaaaa actaccgata aaaattcatc
     6361 acgaaaaaga aaaggaaaat ttgaaaataa ggaaaagaaa atatccaagt tacagcagaa
     6421 aaagcaaaga caagagcaaa aactgaaaaa taagggaatt gacgggaaaa gtcaaagtgc
     6481 taaaagtgca gtaatagcaa cgggtatggc aaagaggtat ttggaaagtg gaaaagagga
     6541 caatgccgga gtaggtactg cttataaggt tacagatcag gtcgaaaata tttcaaggaa
     6601 aatatattat catggaaaaa agaaaaattt aaaaaggcaa aaaaagataa caaaattagg
     6661 taaaagcatt gataaacagg agaagaaact cttttttcaa aagaatatgg aagagatgaa
     6721 aaaaagcgtg gattaccaaa atacctcaag gctcagacaa ttctttaaga gaaggcaata
     6781 taaaaatcag attcaaaaga agtataaaga tagtgtgaaa aacagaataa aaaaatcctt
     6841 tatagagggc agtaaaagat ttggcgaatt tgtaaagggc agagggaaaa agataatatt
     6901 tctatcactt ttagcggtag gaatattttt tatgttattt caggctggga gcatgatgat
     6961 gaatatggga acgggaatgg taagtaatac tgtttcaacc acctacttat catcagaaga
     7021 caccttaaaa gaaatcaatc agaggttttc atctttggaa caggctttgc aagaagaaat
     7081 ggacagtgtg gaggaaaatc atccgggcta tgatgaatat attatcaaag gaaaagagaa
     7141 aattggtcat aatgttcatg aactcttgtc atatatcaca gcccgttatg gaattgtaaa
     7201 gaatatttct gaagtagaaa gtgaactaaa acatctgttt caaaaaatgt atacgctgac
     7261 ttataaagaa gagattgaaa tcagatatag aactgttaca tccagctata cggatgctga
     7321 tggcaatgaa catactgaaa gtcatgaaga gccgtatgag tataggaaac tcattgtaac
     7381 cttagaaaaa agagagatgg acggaattat tagagaagca tttaagcgtt atcctaataa
     7441 tttggcacac tatgaaactt tatttttgac acaaggaaat atgggagaag tatttggaaa
     7501 tattgacctt ataaattcaa atggtggaat tggtggtggt aaagagtatg aagcatcaag
     7561 tgaagtgcaa aagaaaatag tgaatgccgc ttatattaca ccatctccag gagcaggttg
     7621 gtgtgccatg tgggtatcac aggtctatca aaatgcagga cttggattta ttggaggaaa
     7681 tgcttgtgat atgtatcgaa attatacttt tacttctgat aggtcaaagt taaaggttgg
     7741 aatgcttgtt gcagttgaaa gtagcagtag tggtagcagt ttaggtgtta cctatggtca
     7801 tgtaggtatt tatatcggag atggaaaagt aatggataat atcggacaca taagagtaac
     7861 taccctagat gattggattg caacattttg caaacatcac cctgtaggtt ttggatttcc
     7921 accatcagta caaaaataag gagggaatat tttgaataaa aaatatagaa aaaatataga
     7981 aaagcaaaaa gatattcaga aaaaaataga agaactccag ttaaaacagg agatgttaaa
     8041 agaagaacag gaagagatgg aaaatattga ggttttaaag gaataccgaa gtattgacat
     8101 ttctattgac gattttttag aaatgatgag acgttataaa aaagaggaaa aacaagaaaa
     8161 aatgaagtta caggaaatga gaaatacaga aaatcataat aatatggagg aaaatcatga
     8221 aaatcaaatg gaagaataaa aaaatggcga taacattgtc cggagtaatc tttttgatac
     8281 ttgctttact tggaacaatg cttttcaatc accagattgt ttttgcacaa ggtagtttaa
     8341 tcccgacact gattagtccc acagaagttt tagctcaaac taaagtggag gttaagataa
     8401 aatatatatt taaggatgag agtgtatata aggaagaaat aattgaagta gaaaccgggc
     8461 aagttcttga cagtggggac ctaccaatgt tagaggataa tatgaaattt attgacgaat
     8521 ttttgttcta taaagtaaag ggagacggta cagatgagat tatccgtaaa gtagaaaaaa
     8581 ttacagttaa ggataaagaa attcagacag aagaggaaaa gccaaaacag gacgaaagca
     8641 ctgagacgga agataaaaaa acagaagata agggaacaca gacagagctt tctaaagatg
     8701 atatttccaa aatggaaaaa gaggcaaaag agcttcagga taaacttgat aaattaaatg
     8761 gtgaaatcag ggataaagac aaactaagcg ataaacagaa agaaaaaatc aaagaccttg
     8821 aagctgagat tgaaagtctg aaagaaaaaa tgaagaaaga taagggaaat aaagacttat
     8881 cagaagatat gaaaaaggaa atagataagc tgacggaaaa ggtgaaagag cttgagaaaa
     8941 agccaactga aacaaacaaa gctcctgtaa catcacagtc tgttacaccg attagtccta
     9001 tttcagggat taagacaagc tcaggtattt cttctcaaac accacagagt tccggtaaag
     9061 gttcatctga tgcagtaagc tccggcaata ctacaaaaga tacaggtaaa actgaatcaa
     9121 aggagaaaga aaaggaagtt cgctatccca ataagctgac accgaaagct cctgctaata
     9181 acagtagtca ggattcatca atggacggtg caagtagcaa tgtaaatacc aataagggtg
     9241 tggcttcagc tccgtcaaag gcaagaggaa ctgttacaga aaataaagat aatgcgaata
     9301 atgattatcc aattcatcat ggggatagca gcgataacaa agaagcagat aagtattcag
     9361 cagatgcaag acaatttatt actttccaga caaaatccgg aaagacattt catttaatca
     9421 tcaatcacga tgagcaaagt gaaaatgtaa tgcttttgac tgaagtatct gaagatgatc
     9481 ttctgaatat ggtagagaag aaggaaaacc cgcaagaaga aatcaaaaaa atggaagaaa
     9541 cggtaccgga aagcgaagta aaaaaagaag agccgaaaaa ggaagaaggt aaaggtagcg
     9601 gctcatatat ttttttagga atcatcgttc ttgcagtagt tggagcagga tattacttta
     9661 aaatctacaa gaaaaagtag gaagatgatg attatgatga agatgaggaa gaatatgatg
     9721 aatttgaaga tgagtatgaa aaagaggacg atacagaaga tttggaagaa acagtagaag
     9781 aacagcataa catagatgat atggcaatcg actcttatga tgaagaagat gaggaataaa
     9841 gttataaaaa gagaaatgta aaccctgatg ttgcgtttac acttaaaaaa tggtataatg
     9901 caagtgtaaa cgcaacaaag ggggtggatg ggatgaatta tgaaaataaa attgaaaaat
     9961 atttgaagca atcaggtgga attattacaa cagcatactg taaggaaaat aatataccga
    10021 cgatatatct cagtcgacta ttgaaagatg ggagattgtc aaaagtaaga aaaggaattt
    10081 atataacgaa agatggggat tacgatgagt attatttctt tcaacatcag tataaaaagg
    10141 cgatattttc ttatgaaaca gcactttacc tgcttggaca aacagataaa attccttgga
    10201 gtatcgatgt aaccgtttat aacggatata aatttaatga aaaaccgaac ggtttcaatg
    10261 ttcattatgt aaaaaaatca atttatgact taggggtaac ccaaaaacct acaatgtttg
    10321 gaaataaagt taaggtatat tcatatgaga ggacactctg tgattttatt gctcataaag
    10381 aagaaatgga tatagaggtt tatgtaaaac ttattcaatc atattcctct tataaagaaa
    10441 gagatatcca ttccctctat gacattgcaa tgaaaatggg aattgaaaat aaagtaagag
    10501 aggttatgga ggtggcttat gaataaagct aaattaacgg ctctttgcca taaagttagt
    10561 aaagaagtcg gtctttcgtt taatgctgtt atgttatatt attttttaga aagtatttta
    10621 aaaaaattag caggaagcaa atatagtgaa cgatttattt ttaagggcgg ctttttgtta
    10681 tcaagtgtag ttggaattga ttcaagaagt actgtagata tagactttct tttgagaaat
    10741 atgcaactat cagaagaaaa tattgttcaa atgctgaacg aaactttaaa accggaagaa
    10801 ttcgacgata ttttttatga attgcaaaac attgtgccaa tcaaagaaga agatcaatat
    10861 ggaggatttc gtgcaaatat cttatgtaaa atggaaaata taagacagat tgtaccactt
    10921 gacattgcaa caggagatgt tattacacct catccgatag attataagta tgtgagttct
    10981 tttggagaag aagaaataat aatcaaggct tatccgatag aaactatgct tgcagaaaaa
    11041 atacaaacta tttatgcaag aggattttta aatagtagaa gtaaggatta ttacgatctt
    11101 tatattattt ataaattaaa ggataaagat gtaaatgtag agatattaag agaggcttgc
    11161 agaaaaactt ttagttatag aaaaacagaa tttgacatag gtaaaatcat agacttactg
    11221 gaaaaattga aaataaatga agcctttttg aaaagatggc aagcttattc aagaaaaaat
    11281 ctgtatgcga aagatataac ttttgaagaa gtattggaca acggaataaa aatggtggaa
    11341 aaaataaaga atgaaaatta gcatataacg gttttacaat gaaaagaagg cgtcaaacat
    11401 ttttttgtaa gttagttccc aaacaggaaa atggattaaa aaatagaaaa tgaaatatat
    11461 aaaactttaa aagacaattg gagaaatgca aactctgatt gtcttttttc atgtagaaaa
    11521 aaggaggaat ttatgcaaac actggtgata agtgaaaaac cgagtgttgc aataagcata
    11581 tcaaaggtgc ttggagcaac aaaaaagaaa gacggatata atgagggaaa tggatatagg
    11641 gtaagttggt gtgttggtca tttaattcag atggcaaatc cggatgctta tgatgaaaag
    11701 tatgccaagt gggatatggc tgatttaccg attattccca aggactataa gtatgaagta
    11761 gcaaaggcaa ccaagaagca attcaacatc cttaaaaagc tgatgaatga taaagaaatt
    11821 gatacggtta taaatgcttg cgatgcaggt cgtgagggag agagcatttt tagacttgtt
    11881 tataatcaag tgaattgtaa aaagaaaatg aaacgccttt ggatttcatc tatggaagat
    11941 agtgcgatta aagagggttt tgatcatcta aaagacggaa agaaatatga caatctcttt
    12001 gaatcggcac aggcaagagc cattgcagat tggttagtcg gaatgaatat tagtagactt
    12061 tattcctgct tatataatca aaattactct gtcggtaggg tgcagacgcc aactcttgcc
    12121 atgattgtaa aacgagatga cgagatagca aactttaaaa aagaaaaata ttatactgta
    12181 gagctatcta tggacggttt tatactttcc acagacagaa ttgatgataa ggtagcagca
    12241 gagcagctaa tcaatttagt tggtgataag attgaaatta ccgatgtcat tcaaaatgaa
    12301 aagattacaa agccggattt accttttgac ctgacaacac ttcaaagaga gtgcaataaa
    12361 tattttggat actcagctaa gcagactctt gattatgctc aaagtctgta tgagaagaaa
    12421 cttattacct atccaagaac agacagtaga tgccttactg aagatatgat tacaagtatg
    12481 ataaataaca tattgggaca aaatgacttt gatacagggc gtattaaggt catttttaat
    12541 tcaagcaagg taacggatca tcatgctatt ataccgacag taagttcaat gagtgaagat
    12601 ttattgagta ttccggagag tgaagcaaaa gtgtatggac ttatttttaa taagttacac
    12661 gcaagtgtgg gctatccttt aatcgagaat acaacaaaga ttgtagtgac ttttgacggc
    12721 tttaaattta caagttccgg aaaagtaatt aaggatgagg ggtttactaa gtatttaaag
    12781 gaatataaga cgaaaaagaa tgaagatata gaacttccaa atgtaaatat aggtgatagt
    12841 cttaaaatca aggataaaga aatcaaagaa aaatatacgc aacctccaaa acattttacg
    12901 gaaaacacct tattaaaaag catggaaaca gcaggaaatg acgctttaaa aaaaggtatt
    12961 gaggttgaaa gaaagggtat tggcacaccc gcaactcgtg cagggattat agaaaatcta
    13021 atttacaaag gctttattca aagagataag aaaaatcttg tagctacaca taaaggaatt
    13081 agtcttataa caattgttgc agacaacttt aaatctgctg aaacaactgc aaagtgggaa
    13141 atggagttgt ctgatatttc tcaagggaaa tcttcaaagg aagaattttt aagaagagta
    13201 gaagctgaga taagaaatga attatcccgt tataaaaagg attagtctat gtttgatact
    13261 ctaataaaat ttagtaaaga cagagaaaaa ttggattttt atgccacaga taaaagggca
    13321 attcatgaac ttttaaaaag agagcagttt ctatctccta tttatgagcc ggcttgtgga
    13381 atggggcata tcggaaaagt tctggaagaa tacggttata aggtaaaagc tacagatatt
    13441 tgttataggg gatatggaga agaaagagaa gttgattttt ttacagtaac agaaaatata
    13501 ttggatatag taaccaatcc accatatttt tgtgcaagtg agtttttaag gcacgctctt
    13561 gaaatatcag gacctaaagt aaagatagca atgctatttc ggttggcttt tttggaaggt
    13621 caatcaagat atgaattatt taggaaatat cctccaaaga gagtatatgt attttccaaa
    13681 aggcttaatt gtgcaaaaaa cggagaattt gagaaataca aaagcagtgc tattgccttt
    13741 gcctggttta tatgggaggt gggatacaaa ggtattacgg agttaaggtg gattagataa
    13801 aaggatggaa taaaacaact gaaaaaacga aggaggatag tatggataag aatgaagtat
    13861 tacaatcaca ggaaaatcag acaaaggaag ttatgcagga gattaaagag gaatatacca
    13921 aaacagctga ctttttagaa gaacatataa atcagcagct tgtgattgct aaggaaatga
    13981 aagaagagat gcaaaataag gactttgatg taaatatcaa agaattgaaa gcactcaaag
    14041 aagaaatcac cggattaaaa gctgaaatta aacgattaaa cgaaatggaa aatataactt
    14101 ttggttcatt gattataaga gatatcaaat ctgtaggaaa tacccttatc aatttacagg
    14161 aaaaagcggt aggaagtatt aaacatctgt atgataatat gaaacatcag ctttcctata
    14221 accttaccaa agcacaggaa aaatttgtac agatgaaaat aggaattgta aaaggattgg
    14281 taaattccat gcaggatttt atcaaggatc aacaaaagaa actggatagt tgcttagcaa
    14341 aacttgataa tctatctaaa gaaattcaaa aagatgaaga aaaactggaa aaaggcaatc
    14401 tgaataaaga gaaaaccctg ataaaaaaaa gggaacaaag catagaggaa aaagaaagtc
    14461 aaaaggaaaa gatggagaaa aaaccgtctg tgctaaaaaa attaaaggaa aatcagcaaa
    14521 aaatcaagca ggaagaaaag aataaagata taaaggcact taaaaaagat aagggaatgg
    14581 aactataaaa aagaggtggt agttatgaat gacctcataa aaaactatga aaatattcct
    14641 gatgagatga aaaaagagaa gcgttggtgc ctatataaaa tcattcaaag agacgggaag
    14701 aacacgaaac ttccactaat gccaaataaa gagccggcaa aatcaaatga taaagctaca
    14761 tggaatagct atgaggattg tatcatggca ttaaaacata atgttggcga agggcttggc
    14821 tttttcttag gagatggata cattggaata gatattgata aagtaagtga tgacattatg
    14881 gagtacaata cgaatcatca tgtaagctct atgacggctg attttttaag agaagtttcc
    14941 acctatgctg agatttctcc atcgaaaaca ggactacatt ttattggaaa aggagaggtg
    15001 ccgggagaaa gaaaaagata taaaaatctt gaaatttatg ataaggatag gttttttaca
    15061 gttaccggta atgttataaa ggatagagat aggagcaaaa tagaaagtat tgacagtgag
    15121 ctaaagccct tatatgaaaa atatatgcca aagacaaata aaattagtgc tgaaaataaa
    15181 agaagtccaa cggttacttc ttacaatggg gatcaggaca tattagaaaa gttatttgac
    15241 aggggatatt tttcatatgc aggagaagat ttaagacaaa tttactatgg taattatgaa
    15301 cgctatttta acagccaatc ggaggctgat ttttttatgc tacaaaggct gctttactat
    15361 acaggaaatg tagaaatggc aatatcattt atggaaagta gcggactgaa aagagaaaaa
    15421 tggtataaaa gacgaggcaa taccgattat atccactata ttgcagataa ggcgataagc
    15481 tctatcaatc aattttatga ttgggaaaaa gtatatacat caaaggaaaa aatagaagaa
    15541 aaaagatatg aaaataagaa gaaaaaggag ggagatacag tgccaagata tgaatttgat
    15601 gaagtcaaac agattcttga ttttgcaaaa gaagaattta aagaaaatat agacaggtat
    15661 gaaacttatc tcaaagtgat gggaaataac tataaatatc cgtactttaa ccagcttagc
    15721 atatatacgg taaatgaaaa tgcaactgct tgtgcagaat atgactattg gaaaagtata
    15781 ggaagaaatg taaatagagg agaaaaagga atacctgttt tagacattga aagagagaag
    15841 ataaagtata tctttgatgc aagtcagaca gtaagtttaa atcacaacat ttctgaagta
    15901 aagttatggg aatatagcaa taataagcat gtagctgcct tagatactct tatcgatgtt
    15961 ttcaaagaaa aaaacagtaa ccttatattt tctactgaag ataagataaa tacaatcgtt
    16021 tcactatata caaagcaatt actaaataag gtacttaatt ctttaagtga tgaaacttta
    16081 aaggaaaata agaaagtaca aattcttcat tttttggaag aatctgcaaa agtatcggta
    16141 tatgagagaa tgggagttgc attttccggt gatatagaaa aattagagat gctttcaaat
    16201 gtttcaagta tgcaggatat tgacagatta cttttcttta cttcaaacaa tgtaaaaaga
    16261 atacttatgg atataagtag agaaatttca aaagtggaag aaagagaaaa aatttcagaa
    16321 attcaaaaaa gggagcagac aaatagtatt gcggagcgtt atactaatgt tacagatgaa
    16381 attaacggaa ataccgaaat tatagaaaat gaaaaagaaa gaaatgaagg aggtttggaa
    16441 gatgaaagaa accgtagtat tggcgaagaa ggagtacatc ctagaaaacg agatttatac
    16501 accgatcgta aaagagagtc cattcgagag acagggaggg acttacagat tggagaaaat
    16561 ggaggatgga gcggaagtat tagttccgaa tatgaaaatg ccggagaaaa taaacgcaag
    16621 caaactgaac cgatttggca aggagagact gaaatatctc aaagaggaga aacaagagga
    16681 atatcagatt atgctgatgg aagaaacttt aatggatcat ttgatagata ttcaggaaca
    16741 agtggaggat ttcctgaata tagaagagcc gaggatgaaa gaagcttgga aaatgaccac
    16801 agaaatgcag gatcaggact ttctgaaata cacaggactg aagaagaact tggatatgac
    16861 actaacaaaa atggctatgg aacagatcat ttgggtatag atgagtatcg taaagaaaat
    16921 atacagaaga tagaacaaaa tcatgtagaa aatgaggaaa aagaagtcga gaggacttct
    16981 ttttcttttg ctcaaaatgt aggagttcaa ggaagatttg aattaccaat gcagcaagaa
    17041 gagattggtg ctgttttaat tcatggagga aatgaggata atttacattt aaaggtttta
    17101 gccgaatatt ctaaagaaaa aagcatggaa gaattagctg attttcttca aaaaactttt
    17161 caaggaggaa atggatatga actaaatgga aataaggttt gtgcttggta tgaaatggac
    17221 gggatacatt tatccaatga tgtttcctca agagaaaatc ctatgcagat tttaccatgg
    17281 aaagatgcag caatacgcat aggagaattg attgattatg gaaaatacag tacaaatgtg
    17341 gaggtagcag aagccttttc ttttgaaaga gcagaacttt ctgaaaagct gtggttttta
    17401 aaaggagatc taagtgatga ggtaaaaaat cagtttttgc caattctaaa tgaaaaacaa
    17461 agaaacggat atcctgaaaa aacagagtat cttacaaaaa aattggaaga taaagagttt
    17521 agagtgaact taaaagagga gtatatagag ttttttaagg cgtataagga gaactcgaat
    17581 gttttaagat ttcataatca tgatttagat gatatatcaa aacgattaga tgatttggaa
    17641 ctgccaagaa aagaatttac ctcaacactt atagaattac cagcaataca gggatttatc
    17701 acagaagatg aaattgatag atatttaagc agcggtagca atgtatccgg cggaaaagaa
    17761 agaatatata acttttttag ggaagcccat actaccgaag aacgagcaaa ttttttaaaa
    17821 gacgagtacg gaacaggagg acagactcat gctttatcaa gggcaagagg aagtagtgag
    17881 tggcacgatg ctaaggggat aaaacttgaa aaagaaaatt gtaaggatat tattttgaaa
    17941 tggaatcagg ttgtaaaaaa aatagataac cttattgaaa atggaaaata tattcaagaa
    18001 gatgtatata cagagcaaga aagcataaaa actgaggaag aatattttga tgaagatacc
    18061 tatacggaac aaaactctaa agaaaatgaa caagattggc aaagagaaca ggaaattttg
    18121 ctgattcaag atgaaagaga agtatcttat gaagaggcgg aggaaatata tgaaaggcaa
    18181 gcagaaatag aacataatgc ctttgcaacc ggtgtagaga ataacatatc gtcaactcaa
    18241 agtaacaagg attattggat tgtagaattt aatgaaggct caaatctgat agaaaaaaat
    18301 tatgccggag aagttgttac gaaaaaattg cttgatgaaa tcaaggtgct tgacgaaaaa
    18361 attagagttc ataataagac tgtcggtgaa gatgaatacg gagaaatgac agatgaatgg
    18421 gtaggttatt ctaaattcta ttttgaccat attgtagacg ggaaagtaga agaacacttc
    18481 agaatggata tcggggatgg aaatgaggta aaccaaagag attttcaata tctttatgag
    18541 cagattgaac cggaaaaaga aaataaagaa tacgggatgg atagtataga tagtgtcata
    18601 aaagatattt tagaaaaaga atctatgact gtggtatcaa gcaaagatga ttatataaag
    18661 ttatttccat attttagaaa ctttgtatat accgatggtc taaggcttga tgaatataat
    18721 ccgtttgaag atgatgaaaa tatttcggat ttaattcgac tgactttttt ccaaaataat
    18781 gatggagaat atagggtagt ctataacaat gcggacagtt tactgtattc aagcaatgtt
    18841 gactattttt tggagaaaat agaggctgaa aaggtaaggt tagaagataa tatagctgag
    18901 ataccgaatg aagataaaat tgccgttaag gttgggaatt actatgctgt tgtagaaaaa
    18961 gaaagagtaa aggatatatc cttagaagaa acaggagttc gtgtttatcc gaaagaaaat
    19021 aactttgagg gaaaaattta cccattgtat cgtggcagca cctttgaaga aagtgcaaaa
    19081 atagataaac ttttcgatga gattgcaata ggcatgaaag aggtcaattt gaccgattta
    19141 aatgatgttt tttatcttga aaatcaagga ctttatgaaa tttcatcgga tagggtaacg
    19201 gaagaaaaag ccggatacga ttttgaagtg gcaagtttta atgaacagtt tcctgattac
    19261 tataatgaca tttatgtata taacagaaat ttaaaaatag atggtgctaa tcaaaacatt
    19321 gcatatatca atagagaaaa tgaaatacat tttaatgtaa atctaccgga agaagaaaaa
    19381 gcaaaggtgc ttgaaattag agataagaaa gaagtcttat caactcttat ttttaaagat
    19441 gtaaaggagg tcggcgaata tcagtttcat ccacaaagcg aagaatttat cttaaatgaa
    19501 ttgagtatat ctgaagaaaa attaaaagca ccggaacata taacagataa gattgataag
    19561 aaagaaggct atgaggctga acttgttttg gatatgaaaa acaaggagtt aaggcagcat
    19621 ttaagatata acggatatat gttaagtagc aatgtggcgg tttcctatga tagttataaa
    19681 gcaatactta aaaatctttc ttatctgctt gatgataatc atagaaatat tatgcttacc
    19741 ggctatgtca acgaacagat tgaaaaggat aaagcaaagg aagaaagaaa agaacctgta
    19801 tatcaagagg gaatgaatgt aaggtatcaa ggcaaagaat atatcatttc agaaattcaa
    19861 gactataaaa catataaaac aataaagcta gatgattcag aaggatattt aaacggcttt
    19921 ataacgggca gtgaaattat tccttttaga aatgaaagag aacttgattt ggaaatcata
    19981 tctacaacag agaagttaca agaacaaagt ataaatggtg aagatcttat tctgttagat
    20041 attgaagaat ataacaaaaa aggactttcc gttatctttc aaaataaaga gtatgaaatt
    20101 acaggaaata attttaatcc tgtaggaatg agcaggttac aacttgtctc gaatacagaa
    20161 aaactgatga cagaaatttc atatacacct caaagaccgg tcgcaaatct ttatgcaaaa
    20221 aaagatctcc ttgaaaggtt taatttaaat gagaaaaata gtgaaaaaag tattgaagca
    20281 aagcaaatgt ctttaacaga tatatttgag gaacaggata caacaaaggg aaaagaagaa
    20341 atttcaagtg agaaagaacg tgtacctgtc aatatagggg caaaggtaat ctatcaggga
    20401 gaagaatata cagtaagtgc ctttgagtat aataatattt tagagaaaaa tgatatatgg
    20461 ctaaatcctg tatcaaaaaa taatcatcaa attccgattg taagtttttc tgacagagaa
    20521 gagctaaatg aaaagctcat tgttatagat accaatctta acttaggaga agacaagtcg
    20581 gaactgttac atcatagttt agatgtaata aatgataaag gttctgtgat tgccaatcag
    20641 tttattgtaa aagtcgataa tcaaaacagg gaacttacag tatatagtga acaaaatcct
    20701 aatagtcata gagaatttga actttctttt gattatctaa acgggcttgg gcaaattgac
    20761 ggagatggaa ataatctaaa acttacaaag cataaaaaag aaaccattga taaaaaattg
    20821 aaaagttatc attcttggaa agaagatggg gaaaaaagag gaattccggg aatagcaggt
    20881 tcttctatta cttcacctat tactgatgaa atgttttggc agatgaaaga atatgaagaa
    20941 aaattaaaag aggaggaaag atacgcccct gatgataagt atttgggagg tattcctcca
    21001 atcaattaca aaatcacaaa agaagatgaa atcttgccgc cgtccgaaag gcttaaaaat
    21061 aacatagaag ccatcaaggt attaaaagaa attgaggaaa gacatagtca tgcaacaaag
    21121 gaagaacagg atattttgag tagatatgtc ggctggggtg gactttctga tgtctttgat
    21181 gaagaaaagg gaggacaatg gaaagatgca agagaattct taaaagaaaa tctatcaccg
    21241 tctgagtacg atgcagcaag ggaaagtacc cttacagcct tttatacacc gaagattgta
    21301 atagacagta tctatcaagc cgtattaaat atgggatttg aaagtgggaa tatcttggaa
    21361 ccaagtatgg gaactggcag atttataggc aatcttccag acagcatgaa aggcagtaaa
    21421 ttttatggtg tagaacttga cagtataagt ggtaggatag caagtaggct atatcctaat
    21481 gctaaaatac agatcaaagg ttttgaagaa acgacttttt caaataatct gtttgatgta
    21541 gcggtgggaa atgtaccgtt tggagaatat aagatagttg atcgtgagta tgagaaaaac
    21601 aattttctta ttcacgattt tttctttgcc aaaaccttgg ataaagtacg ttccggtgga
    21661 gtagtagcct ttataagttc aagtggaact atggataaaa agagtgaaga tatcagaaga
    21721 tatatttcag aaagagcaga gtttttagga gcaattagac tacctaataa tacttttaaa
    21781 ggcgaggcgg gtacggaagt aacaagtgat attatttttc ttaaaaagag agatcgactg
    21841 gtaaaacttg atgaagaatg ggtaaaactt ggcactgacg aaagaggact gacatataac
    21901 aaatactttg tagataaccc tgatatggta cttggaaata tggaagaaat atcaagcaga
    21961 tttggaacaa gtcttgcctg tgttgcagat gaaaatagta ctctgaaaga acagctggat
    22021 accgccatta aaaacattaa aggaagttat gagaagatag aattaaataa tgaatttgaa
    22081 gtggaaacca ttccggctga tgacagtgtg aaaaattatt cttatgcagt aattgatgat
    22141 aaggtatatt ttagagaaaa ttccgttatg caaaaattga atttaaataa aaatgatgag
    22201 gaaaaagtaa gggcatatct tggaatagaa aaagcattaa gacaggtaat tgcttatcaa
    22261 aaagaagatt attccgatac ggaaattaag gagaagcaag gggagttaaa tcgtatttat
    22321 gatgagtttt ccaagaaata cggaatttta aacagtaagg cgaataaaaa actgtttcgt
    22381 gaagacgcta attattcttt actgtccact ttggaaaagc tggataaaga aggaaacttt
    22441 atagaaaaat ccgatatctt tacaaaaaga acaataaaaa aagcagtagc catagagcat
    22501 accgacaatc tgacagaagc acttatccta tctatttctc aaaaagggaa agtcaatttc
    22561 gagtatatgg aaaagctcac tgaaaaaaca agaggagaaa tcattgaagg attaaaggga
    22621 gaaatattct taaatttaga tggatttgat ccaagtgata cgactccttt ttcttcagcc
    22681 atagacttgg gagatttttc aagatcttac gtaactgctg atgaatattt atctggaaat
    22741 atcagagata aaatagaagt aatagattcg tatataaaga atgtagaaca tgaatttgaa
    22801 caaaatgaac agcttgaaaa tattgatgca gatgtactga aacagggtag tgagacttta
    22861 aaaaaagaac tgtccagttt aaattaccaa agacaaaagc tgctagaagt aatgccaaag
    22921 gagcttgagg caagtgaaat aaccgttaga atgggagcaa cttggatacc tgagaaagat
    22981 tataagagct ttatgttcca tcttctaaaa acatcggcat ctaatagatg gaatattgat
    23041 attaaatata ccaattttac aggggagtac agagttgaag gtaaaagtat agataaagga
    23101 aacgaccttg ccaatttcac atacggaaca agcagagtaa gtgcatataa actgattgaa
    23161 gatacattaa accttagaga taccaatgta tatgatcaag tcattgatga aaacggaaag
    23221 aaaagttctg tactaaatca aaaagaaacg atgcttgcaa gaagtaaaca ggaaattatc
    23281 aaagaagagt ttaaaaattg gattttcgat gatatagaca gaagaacaag gcttgtaaaa
    23341 gaatacaatg agaaattcaa ttcgataagg cttagagaat atgatggaag taatttaact
    23401 tttgacggaa tgaatcctga aatagagctt agacctcatc aaagagatgc gattgctaga
    23461 ggacttttcg gtggaaacac cctacttgca catgaagttg gagctggaaa gacttttgag
    23521 atgataggaa ttgctatgga gtctaaaagg cttggaatga gtaacaagtc aatgtttgta
    23581 gttccaaacc atattgtaga acagtttggt agagagttta atgaactgta tccggcagca
    23641 aatattcttt gtgcaacaga aaaagacttt acaccagata aaagaaaaag attttgctca
    23701 aggattgcaa ccggtgatta tgatgcggta attatagggc attcgcagtt tgaaaagatt
    23761 ccaatttcaa agcagcgaca ggagtatgaa cttcaaagtc agattgatga aattatagat
    23821 tttatcgaag aatataaaag gaatagagat cagaaattca ccgttaagca gcttgaaaaa
    23881 acgaaaaaag gactggaggc aaaactaaag aaattaaatg atgattatag aaaagatgat
    23941 gtcgtaacct ttgaagaatt ggggatagac aagctatttg tagacgaagt tcatgctttt
    24001 aaaaatttgt acgtttttac aaaaatgcgt aatgtagcag gaattacaac cacagattct
    24061 caaaaatcaa gtgatatgct gatgaagtgc agatatatgg atgaaattac cggtaataag
    24121 ggtattgtat ttgcgacagg aacccctgtg agcaattcta tggcagagct ttataccatg
    24181 cagcgttatc tccaatatga cgaacttaaa aaaatgcact tgcaacactt tgattcttgg
    24241 gcatctactt ttggagaaac tgttacagca attgaactta atcctgaagg gaacggatat
    24301 cgaagcaaga caagatttgc aaaattttat aaccttccgg aactgatgaa tatggtcaag
    24361 cagtttatgg atataaagac tgctgatgta ttaaatcttc ccgttccaaa tgctcattat
    24421 gaaacgataa aaaccaaacc gacagaagaa caaaaacaaa tccttgaaac tttttctgag
    24481 agagctgata aggttagagg aaaacaggtg gattcctctg tcgataatat gcttctgatt
    24541 actaatgacg gaaagaaaat ggcacttgac caaaggttaa ttaatccatt acttcctgat
    24601 gatccgaaca gtaaagtaaa tacctgtgta aataatatat tcagtatttg ggataaatat
    24661 agggatgaga agtccacaca attagttttt tgtgatatgt caacaccatc aagtgaattt
    24721 aatatttatg atgatataaa ggagaagctg acaaaaatgg ggattcctaa aaatgaaaca
    24781 gagtttattc ataacgcaaa gaacaacaaa gaaaaagata agattttcga taaggtacga
    24841 aagggtgaaa ttcgtgtgct tctcggttca acgcagaaaa tgggagcagg gacaaatgct
    24901 caaaataaat tgattgctac ccatgatctc gatgtaccct ggaggcctgc ggatttggag
    24961 cagagaaaag gaagaattgt aaggcaaggt aatgaaaatg atgatgttca tatctttcgt
    25021 tatattacgg aaaatacctt tgatgcgtat cttttccaaa cacttgaaac caagcaaact
    25081 tatatatctc aaataatgaa ttcaaagaca cctgtaagag tagcggagga tattgatgaa
    25141 gctacattaa attatgcgga gattaaagca cttgcaacag gaaatccgct tattcgtgaa
    25201 aaaatggacc ttgatgttga ggtaagtaaa cttaaaatgc tggagtccaa ttttaaatcc
    25261 aacc
//
LOCUS       DARYXZ010000033        24218 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYXZ010000033 DARYXZ010000000
VERSION     DARYXZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24218
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            310..2454
                     /gene="pnp"
                     /locus_tag="TV186_001243"
     CDS             310..2454
                     /gene="pnp"
                     /locus_tag="TV186_001243"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL1532639.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
     gene            2447..3199
                     /locus_tag="TV186_001244"
     CDS             2447..3199
                     /locus_tag="TV186_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL1532640.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            3211..3747
                     /gene="cysE"
                     /locus_tag="TV186_001245"
     CDS             3211..3747
                     /gene="cysE"
                     /locus_tag="TV186_001245"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL1532641.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            3865..5208
                     /locus_tag="TV186_001246"
     CDS             3865..5208
                     /locus_tag="TV186_001246"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL1532642.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            5201..5608
                     /locus_tag="TV186_001247"
     CDS             5201..5608
                     /locus_tag="TV186_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL1532643.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            5825..6613
                     /locus_tag="TV186_001248"
     CDS             5825..6613
                     /locus_tag="TV186_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532644.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            6662..7408
                     /gene="rlmB"
                     /locus_tag="TV186_001249"
     CDS             6662..7408
                     /gene="rlmB"
                     /locus_tag="TV186_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL1532645.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            7409..7927
                     /locus_tag="TV186_001250"
     CDS             7409..7927
                     /locus_tag="TV186_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL1532646.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            8111..8971
                     /locus_tag="TV186_001251"
     CDS             8111..8971
                     /locus_tag="TV186_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1532647.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            9510..9956
                     /gene="rplM"
                     /locus_tag="TV186_001252"
     CDS             9510..9956
                     /gene="rplM"
                     /locus_tag="TV186_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL1532648.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            9976..10368
                     /gene="rpsI"
                     /locus_tag="TV186_001253"
     CDS             9976..10368
                     /gene="rpsI"
                     /locus_tag="TV186_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL1532649.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(10483..11574)
                     /locus_tag="TV186_001254"
                     /pseudo
     CDS             complement(10483..11574)
                     /locus_tag="TV186_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(11628..12146)
                     /locus_tag="TV186_001255"
     CDS             complement(11628..12146)
                     /locus_tag="TV186_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1532650.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            12299..12583
                     /locus_tag="TV186_001256"
     CDS             12299..12583
                     /locus_tag="TV186_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1532651.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            12592..13077
                     /locus_tag="TV186_001257"
                     /pseudo
     CDS             12592..13077
                     /locus_tag="TV186_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            13129..13416
                     /locus_tag="TV186_001258"
     CDS             13129..13416
                     /locus_tag="TV186_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1532652.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            13431..13721
                     /locus_tag="TV186_001259"
     CDS             13431..13721
                     /locus_tag="TV186_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532653.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            13714..14076
                     /locus_tag="TV186_001260"
     CDS             13714..14076
                     /locus_tag="TV186_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1532654.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            14076..14432
                     /locus_tag="TV186_001261"
     CDS             14076..14432
                     /locus_tag="TV186_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1532655.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            14776..16320
                     /locus_tag="TV186_001262"
     CDS             14776..16320
                     /locus_tag="TV186_001262"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL1532656.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            16322..17578
                     /locus_tag="TV186_001263"
     CDS             16322..17578
                     /locus_tag="TV186_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1532657.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVV
                     NFRRGSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVP
                     KGTVIVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFA
                     RGSTLKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQY
                     AYFRDKLLTFTAEGVYTDSTVQTRPN"
     gene            17583..18188
                     /locus_tag="TV186_001264"
     CDS             17583..18188
                     /locus_tag="TV186_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1532658.1"
                     /translation="MTWVFGPIKVELGAVCDVVRGNGLQKKDFVNEGYPVIHYGQIYT
                     FYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVGKALVWEGAEDVCIGGH
                     SCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKNLEKAIIILPPVYEQGR
                     IVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
     gene            18203..19411
                     /locus_tag="TV186_001265"
     CDS             18203..19411
                     /locus_tag="TV186_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1532659.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     AAIYLSDVIGSAENTDLKFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMKATDEIED
                     EKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYG
                     RWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNS
                     FDSIYRFKED"
     gene            19414..22509
                     /locus_tag="TV186_001266"
     CDS             19414..22509
                     /locus_tag="TV186_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL1532660.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            22677..24128
                     /locus_tag="TV186_001267"
     CDS             22677..24128
                     /locus_tag="TV186_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1532661.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
BASE COUNT         7395 a         4266 c         5487 g         7070 t
ORIGIN      
        1 gcaggtcttt ttttgctgcg tcatcagcgg cttagcgtgc ttggctgtag ggctatagtg
       61 ataaaagaga gtgctgctgg tattgacagc cctttcaaac tttttctagg aatgcctttt
      121 agggtcgtga atttttaact attttatggt aaaatgtagc agatacgtcg tttgatacaa
      181 agaggagtgt gtaattcctt acagattgct ctttgtagca aaacaacgta tagccataaa
      241 aaataaaagg ctagcaagct ttggtcgggt caaacggcta tggtaggcta gctcgttcaa
      301 ggagaaagaa tgtcaaaaca aacatttaca acaacctttg caggcaaacc acttgttgtt
      361 gaggtcggtc aagtagccaa gcgagcaaat ggtgccactg tcgttcgtta tggggagtct
      421 acagtgctaa ctgctgctgt catgtctaag aagatgtcaa caggagactt tttcccgctt
      481 caagtcaatt atgaagaaaa aatgtatgcc gcaggtaaat ttcccggtgg ctggatgaag
      541 cgtgagggac gtccgtcaac agatgcgacc ttaaccgctc gcttgattga ccgccctatc
      601 cgtcctatgt ttgctgaggg ctttcgtaat gaggtccagg tgattaatac tgtcctgtct
      661 tatgacgaag atgctagtgc ccctatggct gctatgcttg gtagctcatt agccctatcg
      721 atttcagata ttccttttaa tgggccgatt gctggtgttc aggtggccta tgttgagggt
      781 gaatttatca tcaatcctga taaggcccag caggaggctt cattattaga gttaaccgta
      841 gcaggaacaa aagatgcgat caatatggtt gaatctggtg ctaaggaatt gccagaggct
      901 attatgctag aagcactttt ggttggccat aaggctatac aggagttgat tgcttttcaa
      961 gaagagattg ttgcagcggt gggcaaggaa aaggctgagg tagagctatt acaggttgct
     1021 gctgatttgc aggctgagat catagagact tacaatgctg atttgcagca ggctattcag
     1081 gttgaggaga aaaaagcacg tgaagccgca accgaggctg tcaaggagcg tgtcatagct
     1141 gcatacgagg agcgttatgc agcagacgaa gagcatgacc gtatcatgcg tgatgtggct
     1201 gaaattttgg agcaaatgga gcatgctgag gttcgtcgcc tcatcactga ggataaggtt
     1261 cgtcctgatg gtcgtcgtgt tgatgagatt cgtccgcttg ctgctgagat tgatttctta
     1321 ccaagggtgc atggctcagg cctctttacg cgcggtcaaa ctcaagcttt gtctgtcttg
     1381 actctagccc caatgggaga tactcaaatt attgatgggc ttgagcctga gtacaaaaaa
     1441 cgcttcttgc accactataa tttccctcaa tattctgttg gtgagacagg ccgctacggt
     1501 gcagcagggc gtcgtgaaat tgggcatggt gctttaggcg agcgcgctct tgcacaagtc
     1561 cttccaagcc ttgaggcatt tccatatgct attcgtctag tggctgaggt attggaatca
     1621 aacggttctt cctcgcaggc ctctatctgt gcagggacgc ttgctttgat ggctggtggt
     1681 gtgccgatca aggcaccggt tgcgggtatt gctatgggac ttatctctga tgggaccaat
     1741 tatactgttt taacagacat tcaggggtta gaggatcatt ttggcgacat ggacttcaag
     1801 gttgctggga cacgccaagg gattacagca ctgcaaatgg atatcaagat cgaaggtatc
     1861 acccctcaaa tcctagaaga agccttggcg caggctaaaa aggctcgctt tgaaattctt
     1921 gacttgattg aggcaaccat tgctgagcct cgtccagaat tggcaccaac agcaccaaag
     1981 attgatacca tcaagattga tgttgataag attaaggtgg ttattggtaa gggtggcgaa
     2041 accattgata agattattgc tgagacaggt gttaagattg acattgatga ggaaggaaat
     2101 gtttcaatct actcaagtga tcaggacgct atcaatcgtg ctaaggaaat cattgctagc
     2161 ctagtacgtg aggctaaggt aggagaggtc taccatgcta aggttgtccg tattgaaaaa
     2221 tttggtgcct ttgttaacct ctttgacaag acagatgcgc tggtgcatat ctctgaaatt
     2281 gcttggagcc gcactaccaa tgtctcagat gttcttgaaa tcggtgaaga ggttgacgtt
     2341 aaggttatta aggttgatga taagggacgt attgacgcat caatgaaagc cttggtgcca
     2401 cgcccgccaa agccagaaaa atcagaagca aaaaaagaag gcaaacatga ctaatacaaa
     2461 tgaactagat attcgtttaa gagcctttat caatgcccct gataattttt tagatagcgt
     2521 ggccttggtt aatgcttttc accagtatcc ggtgtgggca gcaaaaaagc cctatgctat
     2581 tgagattgaa ggggtaagga tttttcctgt attcacagat aaggacgaca tggcgacctt
     2641 taaagaggag caaaagagtg cacaagctca gtattgggta gagcgctctg ctcttactgt
     2701 cttggaggag gctgttcatg caggtgctgc tgggctaggc tttaatctca agaaaaaggg
     2761 agattttggc aattctacag tgttcaagtc tgctgatatg attcagttta tgaacaatta
     2821 cacaacgatt ttgaatacct tgatgagtga tgacaatagc gcagcagata ccctggatag
     2881 gctttatctg gtgccggcct ttgtttaccc taaggaagag gagcattact atgacaggct
     2941 ttttccaacc atgtcaactc cagaggggaa gcgttatgtt cctgcctttt caaatcttca
     3001 gagcttcgct aaatggtaca atcaagagga gtttggcggc ctttttagga aatcaggtgg
     3061 tgttatctta acatggaaga tagcagacat ttatcagcca agaaatggca ataatgacat
     3121 agacgagacc tttggggttg ctattgaccc ctttgatgat cagcagattc ttgttgattg
     3181 gtctgatatt gacacataaa aggagtttaa atgggctggt ggaaggacaa tattgatatt
     3241 gtaaagcaac tagatcctgc tgcacgtagc accctagagg ttatcctaac ctaccctgga
     3301 ttaaaggcct tggcagcgca caggctgtca cattttttgt ggcagcatgg ctttaagctg
     3361 ctggctcgaa tgcatagcca gttttggcga ttttggacac agattgaaat ccacccagga
     3421 gctaggattg cttcaggtgt tttcattgac catggggctg gcttggtgat tggtgagacg
     3481 gccattgttg aaaaaggagc catgctttat catggagtga cgcttggtgg aactggaaaa
     3541 gatcgaggga agcggcaccc tactgttcgt gagggggcac tgatttctgc ccatgctcaa
     3601 attatcggtc ctgtcgagat tgggaaatcg gctaaggttg gagctgcagc tgttgtgttg
     3661 actgatgtac ctgctggcgt gacggtcgtt ggcattccag cccaaattgt tcgagtgcat
     3721 gagaaaaagc cctcaaggca ggattaatag ttttctctag aggcagtcag ccaaaaaacg
     3781 ggagagttag agccctatgc ttacctcagt tgctgacagc ttgcgcagtc taggagaaaa
     3841 ggataaaaac aaaagggaaa agtgatgata aaaatctatg ataccatgac cagaagtctg
     3901 cgagagtttg taccaataac tgataaggtg gtcaatatgt atgtctgcgg gccaacggtt
     3961 tacaattata ttcacattgg caatgcacgt tcggctgtgg cctttgatac gattcgtcgc
     4021 tactttgaat acgcaggcta tacagtcaat tacatttcaa attttacaga tgtagacgat
     4081 aagattatca aggcagccaa ggaatcaggt gtatcaccca aggaattggc ggacagattt
     4141 attgctgcct ttatggagga taccaaggca ctcggtgtga agccggccac caaaaatcca
     4201 cgcgtcatgg actatatgga cgagatcatt gcctttatcg ctgctttaat caaaaaaggc
     4261 tatgcctatg agtcggcagg tgatatttat ttccgcgtgg caaaggcatc aaattatgcc
     4321 agactggcta ataaaacgat tgctgatttg gaggctggtg ctagtggtcg tacagatacc
     4381 gaaactgctc tcaaggaaga tcctttggac tttgccctat ggaaatcagc aaagctaggc
     4441 gagatttctt gggcaagtcc ttggagcgcc ggtcgtcctg gctggcatat cgagtgctct
     4501 gtaatggcaa ccgagctttt gggagatacc attgatattc atggtggtgg cgcagacctg
     4561 gaattcccac accataccaa tgaaattgct caatcagaag caaaaactag caaaactttt
     4621 gccaattact ggatgcataa tggctttgtt aatgttgaca acgaaaaaat gtctaagtca
     4681 ctgggcaact ttgtgactgt tcatgatctg ctaaagacgg tggatgggca aacgctacgc
     4741 tttttcttgg ctactcagca ttatcgtaag ccgattaatt ttactgaaaa agctattcat
     4801 gatgctggag ttaacctcaa atacttgaaa aacacgcttc agcagcccac agtagccact
     4861 gcagatgcta gccagcttgc tgcctttatc actgccttca aagcagccat gaatgatgat
     4921 tttaatacag caaatgggat tacagtctta tttgacatgg caaaatggat taactccggc
     4981 gcctattctg aggctgtcaa atcagcattt gaagagatgc tagctgtttt tggcattgtc
     5041 tttgaagcag aaagcctaga cacagagatt gagcagctga ttgctgagcg tcaggaggca
     5101 cgtgccaatc gagattttgc aagggcagat gctattcggg atcagttggc agctcagggg
     5161 atcaagctgt tggatacaaa agaaggtgtg aggtggatac gtggctaatt cagttgatgt
     5221 caatttgatt aatggcattg cccttgcctt tgttggtgat gctgtttatt cttactatat
     5281 tcgtcgtcat ctgattttcc aaggccagac caagccaaat aagctccact accttgcaac
     5341 aaaatatgtt tctgcaaagg cacaggcttc tctgattcag gccatgctag aagcacaact
     5401 attgaccgaa aaagaaaaag acatctacaa acgaggccgc aataccaaca gccataccaa
     5461 ggctaaaaat gctgatgtag taacctatcg tatgtcaaca ggctttgaag ctattatggg
     5521 ctaccttgat atgacaggtc agacagaacg gctagaactg ttgatccagt ggtgtatcaa
     5581 gcaggtggag aacagtcctc aatcataatg atgaatcatc taaaacattc tctgtgtcac
     5641 tagcgatctg ccatcgctca aagtcatgag agtgttttta tgttgtgttt aaaagttatg
     5701 tcacaatata gatacacacg aaacataaaa taaatatttg taacaaaaac gtaacaaaac
     5761 tattgaaaaa ttttccgaat agtttataat gaaagagtca taataaaatg ataggagaat
     5821 gtctatgaaa ccaatgagaa acgtagcctt agttatttca gcaatgttac tgttaagctc
     5881 acaggccttt gtatcagcag tagcagcaca ggacaatcaa ccaaccatag cagttcaagc
     5941 acaggcagca gctgaggcca atgtcagtgc tcgtatgcgt tcagatcagc ccgttattga
     6001 agctaacatt gctaccagtc agccagttag ccaaagcact gaggctacta ttttactaaa
     6061 ggatgccaaa ggcaacgcga ttaatagcac agcctatacc atgcaggctg gtcaaagccg
     6121 gttttcagta tggtttgacc ttacgaacct aaaggttagt gattatagta tatcagtgag
     6181 tgttcctgat aaagaaaagg cctttagtgg tagctcagca cctattcatt ttgatggaaa
     6241 gccaaccaaa aataccccag agacagaaca gaaaaacagc aatccagtac cagctaataa
     6301 ccagcctaaa cccgctgcta gcggcagggt gacaagcact gagcaacccc aaaatgtgcc
     6361 tagcgcgact gctagcgcca atcatatgac aagaaccaat catcgatctg ataaggtcct
     6421 aaaggcaagc tcaagcaaca caccatcagc tgccaaatca atagactctg ctgagaaagg
     6481 caagggcatg ctttctgata gcacagccca agataaagag caaaaaggct ttccttggct
     6541 gctatcatct ctaattgcaa ttacagcagc tgctttactt gctcttgtca tcaaagctgt
     6601 tcacaggaaa taaaaagagc agcaagagct attttattgc tttcgtggta taataaaaac
     6661 catgaaagct aaagaaatca atgaaaccaa ggatattgtt tatggcgtcc atgccgttac
     6721 cgaaagccta ctagccaata ctggaaataa gctttacatt caagaggatc tgtgtggtaa
     6781 gcatgttgat cacatcaagg atttagccac tagtaagaag gtgtctatct cttggacaaa
     6841 aaagaaagct ttgaccgaaa tgacagcagg agctgttcat cagggctttg cgcttcgagt
     6901 gtcagccttt gcttatactg agctagatga gctgctagag ctggcacagc aggaggataa
     6961 tcccttgctg ctcatcctag atgggctgac agatcctcat aattttgggt ctattttaag
     7021 aacagccgac gcaacaggtg tttgtggtgt gattatccct aagcatcgtg ctgttggtgt
     7081 gacaccagtg gttgctaaga cctcaacagg agctgttgag catgttccaa ttgctcgcgt
     7141 gacaaatctt agccaagcat tggatcagct aaaagcaaat ggcttttggg tcttcgggac
     7201 agatgtaact ggtacaccat catacaagtg gaatacctca ggcaagctgg ctttgattat
     7261 tggcaatgag ggtaagggca tttcagctaa catcaaaaaa caggtagatg aaatgattac
     7321 cattcctatg atgggtcatg ttcagagctt aaatgctagc gttgcagctg ctattttgat
     7381 gtatgaagta tttagaaata aattatagat gaaaaaaaga ctattgctgg ttgatggcta
     7441 taacatgatt gccttttggg aatcaactcg tcagtttttt aagacaaacc aattggatca
     7501 agctagaagg atcttgctaa ataagctgaa caactatgcg cattttgatg atagtgacat
     7561 tatttgcgta tttgatgctc agtatgttcc aggacttaga cagcgttatg accaatatag
     7621 gatttctgtt atttttaccg aagaggaaga aacagctgat agctatattg agcggactgc
     7681 tgctgagcta aacaccgctc taaccatggt agaggtggct actagtgatc tgaatgaaca
     7741 gtggacgatc ttttcccaag gcgccttgcg tgtcactgct aaagagcttg agcagcgtgt
     7801 taatgctgtt aagtcggatt tagataagct gtcacaggat attgatctta aaaagcctag
     7861 actgggtccc tttgatcaag ggcagcttaa tcagctcaag gactttatga atcgattaga
     7921 tgattaataa gcttatcttg ctagcttttc taggtatgat tctccaggct gctagagcag
     7981 ctcatacgat ctaacggtga tcatttctga ggcagctggt tcttattgct ttcttagctg
     8041 atattttttt gttatactat gagaaaatca tttgattatt aaacgataat gacgttactt
     8101 gggagttcag atgacatttg tattgatgac agattcaaca gcggatttag attctttttg
     8161 ggcaaaggag cataacatcg atatagtagg cctaactgtt gaatgtgatg gcaaggttta
     8221 caagacggtt ggtccagata gattaacgag tgatgctttg ctagctatga tgaaaagtgg
     8281 gagccagccc aaaacaagcc agataaatgt tggtcagttt gaagagattt ttcgacatta
     8341 cgcagctgat aaccaagctc ttttatatat cgccttttct tcagtcctat caggtaccta
     8401 tcaaagtgct gtcatggcac gtgagctggt tttggaggac tatccggacg ctgtaattga
     8461 gattgttgat agcttggctg cagcaggagg agagggctat ttgaccatgc tagcctcgga
     8521 ggcgcgtgat aatggaaaaa gcctattaga aaccaaagcg ataatagaag gtattttgcc
     8581 tcgcttacgc acctatttct tagtagatga tctttttcat cttgtgcgag gaggacgctt
     8641 gtcaaaaggc tctgctttta taggcagcct agtgaatatt aagcctctct tatggattga
     8701 tgccagcgga aaattagttc ctattgccaa gattcgtggc cgtaaaaagg ccattaagga
     8761 aattgctgac agagccacaa aagatattgc tgattcaact gttgttgtgt cctatactag
     8821 tgatcagact ggggcagatg acctacgaga acagctatta gcacatgaag gtatcagtga
     8881 tgtctttatg ctgccgctcg gaccggtgat tgctgctcat acaggtccag ataccttagc
     8941 ggtctttgtc atcggcaagg aaaaaagata aaaagaaaag gattgaagcg cttgtttcaa
     9001 ttcttttttg tcgactatag cttgttttag ctgtgatgcc gcttaagagt atgggtgttc
     9061 gcatttttta tttttaatca aaagttagaa tgaattgttt gacaatgaag gtgcgcgtgc
     9121 aggtaaggaa ctagcataac agaacagggc tttttgattt gccagaagtc agatgtcaaa
     9181 tgttttagca gttgacagga gctttggtca ttccaccact aatctttgta ttgttatttg
     9241 cataggagct aacaggaact gagcggattt tttggaggga agtcaaggct aatagtccag
     9301 ctcaaaagca agcctgttct tcttgtgaaa aagcaaaaat aatcaaagaa atagagctaa
     9361 accacttgac tatcagttaa gaagtttgat actatagtag acggtattgt ttaccccatt
     9421 tgaaaggccc cggaaccttc caaatacctt cgatggaccg gaacatccat cactaatgta
     9481 aacaaaaacg aattcgtata ggagaaatca tgaacaaaac aactttcatg gctaaaccag
     9541 gccaagttga acgcaaatgg tacgttgttg acgcaacaga tgtgccactt ggacgccttt
     9601 ctgcagtagt tgctagcgta cttcgcggaa agaacaagcc aactttcaca ccgcacactg
     9661 atacaggtga ctttgttatt gttatcaatg ctgagaaggt taaattaact ggtaaaaaag
     9721 caactgataa ggtttattac actcactcaa tgtacccagg tggcttgaaa tcaatcactg
     9781 ctggtgagct tcgctctaaa aatgccgttc gtttgattga aaagtcagta aaaggcatgc
     9841 ttccacacaa cactcttgga cgtgcacaag gtatgaaatt aaaggtcttt gttggcggtg
     9901 agcacactca tgctgcacaa caaccagaag tacttgatat ttcaggactt atctaagaga
     9961 aaggagcatt aaataatggc acaagcacaa tatgcaggta ctggtcgtcg taaaaacgct
    10021 gttgcacgcg ttcgtttagt tccaggtact ggtaaaatca ctgttaataa aaaagatgtt
    10081 gaagaataca tcccacatgc tgacctacgt ttagtcatta atcagccttt tgcagtgact
    10141 tcaactgaag gctcatacga cgtttttgtt aacgttgtag gtggtggtta tgctggtcaa
    10201 tcaggtgcga ttcgtcatgg tatcgctcgt gcgcttcttc aagtggaccc agatttccgt
    10261 gactcactaa agcgcgctgg tcttcttaca cgtgacgcac gtatggttga acgtaaaaaa
    10321 ccaggtctta aaaaagcccg taaagctagc cagttctcaa aacgttaata tccagttata
    10381 ccaacgtttc agagcacttt gcgaagtttt cgcaaggtgc ttttttgttg aaaaaagcac
    10441 cttggtaatc tgttgagacc tagttttaag agaggttaag ttagaatgac tataagtatc
    10501 taaagtcatc tggctgctag catgacctag acgcttagcg gtattaactg ggtcaattcc
    10561 catttcaatc atcaaggttg cgtgagtgtg cctaaaccca tgtgggctaa tctttttaag
    10621 attatgcttt cgtataatgc gttttagaat attgttgata tagtcagcgt gtaagggttc
    10681 tatctcacca tctctgttgc agtatgtaaa cataaattct ttgtcgagag aaaggggctg
    10741 tactgataat tgcccctttt ctttgctagt ttcctgtttc catttgttga ggatagaaca
    10801 ggtttcatca tcaagataga tagagcgtac tgagaatgta tttttagttc ctttttcaat
    10861 ggcatgacca tctattcttc ctaaactttt gctgactgtt aatagttgat tctcagaatc
    10921 aaaatcttcc catttgaggg cgtagagctc tccttttcgt aacccgctgt atgctagtaa
    10981 tcgaaataga gcataatgtt tataaggttc attttctaaa atgattgtca aaaaatgatg
    11041 caactcgtta actgtccagt agttctcact gacagttttt ttgagtttag gcataataac
    11101 tttgctcata ggattacgtt caatatgatt catattgatg gcaaattcaa aggttttaga
    11161 ggtgtatgac ttgatttgct tcatgttctt gaatgatttc gctttatctg tgataaaggt
    11221 ttggcagtct agcggactga tttttgaaat ctttttctct ccaaaggttg gaagaatatg
    11281 aaggcgatat aaatcggccg ttttagctgc agtagttgtt tcaacggtat ctttgtaagc
    11341 ttcataccac ctttgatata gttcttggta agtataggtt gtttgagcag taagatgggc
    11401 aaaagttcca ctattcagct gatgattaac agcagtttca tgagctttgg cagctttacg
    11461 cgtcttgaat cctcgtttag tgtaatattt tttcttaccg tagtcgttta gaccaaggta
    11521 aactttaaca aaataggtaa ttccttttgt agattggtat ttgtgtacag acataacagt
    11581 tctccgtttc taagttttcg gagcttatgt aattgagaaa tattagtcta ttttctgtca
    11641 cgatctgctc gtctaatttg aaactcttcg gtttgtatcc atgttttcca aatatccgat
    11701 ttttggcctt ggttattcat aaacttaatt aagtctttga taaaggtttc ttcataatcc
    11761 attaagtagt tagaaagaat acgtctaaag tcatctgaga aaacctcgtt taagggcata
    11821 gacaaatgaa tctctcctag ttcgattcct ttcttaagct tctccatatc gcttttaaaa
    11881 ggtgttacag aagtaatttc agatgtcttg aaactatcag tgacgatttt taaatttgac
    11941 ggagcgtact tttcttcgtc aattccaagg atgtatgcca ctgagacacc aaaataatcc
    12001 gctaactttt gagcattctc ttttttaggt tttcgtattc cttggttata gctagatagt
    12061 gttgggtagg atatatctag cgcttcactg atacttttta tttttttgcc actttcttct
    12121 ataagtttag ctatattatt agtcatagat tcctcctaat tgatattcta ccacatttaa
    12181 tacaaaaagt ataataccac ttgacaagaa tacaaaaagt atttataatt taaaatgtat
    12241 aataaaatat acaaatttcg gagtttattt aattgagaaa tggaaacgag gtaatgatat
    12301 gtctgaagaa gcgactttag ttgttcaact tcccaaagtt ttggaaaaac aattaagggc
    12361 acattatgat gaaatggttt ctacagctat tgaaagagcg ctagaggata aagaattata
    12421 taaacctatg gttcggatgg cagccctttc tagatggctt gatgtgtcaa cgacaacact
    12481 tcaaaagtgg acgcgagaag gaatgcctac aatggttatt gatggtgtga ctctgtacga
    12541 taaacgtgcg gttacacgtt ggttgaagca atatgaaaga tgaggtaaag aatggctaat
    12601 agacgaatgt tgagtaaaac ggtggtgcag atacaacgat ttttacgcct accacttgaa
    12661 gcgcaggcgc tttactgtca cttggtagtc aatgcagatg atgatggtat tgttgaagct
    12721 tttcctgtta tgcggatgat taatgctaat gaggacagtt tgaatttatt aactcttaag
    12781 cagtatttac tcttgttaaa caatgaaatg gtttacttta tcaaggattt ctttgagcag
    12841 aataccatca aagcagatcg ttacacaccg agtagtcatc gtcaacttct tatagattat
    12901 ctgaaggata atcagttgtt ggagtgtcta aatctaggac cacgcttgat taattatctt
    12961 caaaatactc ggctccaagt tggagccagt ctggatccag atgggaaccg caatataatt
    13021 aaagataaga taagtaaaga taggataggt aaagataagt taagtcaaga taagatagga
    13081 ttagataatg atccaatctc atcacaactg actgatgaca tctggttaat ggaaacacta
    13141 tggcatcgag aattaaccca acaggagaaa gtattattag aaggattcgc ggttaatgat
    13201 tctttattgc agttagctat tcagaaaaca gaggagcttg agccaaagaa acaaaacatg
    13261 agttatgtca aagggatact aatgaattgg gaagctagag ggtttataac tgttgaccaa
    13321 gtgatagcat ctgaagaaga ctaccgtcca ttagaaattg caaatgtaga agtttcagaa
    13381 gatttcttag cagctatgga tatatggaaa gactagggga ataatgagtt atgacagtat
    13441 attatcaatt agaaaatatg ttagtggctg ggtttaagtc acaagatgag tacgaccgct
    13501 atcaggctct caagagggac tatgaagggg agtcagagga ctatagcttt tcaatcagag
    13561 aaatcacaaa tcaacttgaa atcatttgtc agacctcaga gaatgatttt ccgaacttat
    13621 cagaagcatt aatgattgat tatttagaac tggtaggaga gttgaaacga tatgatacta
    13681 atcaggcaga caggtattta gggatggttc gtcatgtctg aacgtatcag aactatttta
    13741 aagaagtttt atgtgacgga attgcagaat gaagtactta atcaactagt aaatgataca
    13801 ggcttgcaaa cattctctaa ttatgctcgt cggatgcttt ttaaggaaac atcactcttt
    13861 atgcgatttg atgaatctca gtttgatgag ttgatttatt ctttaaggcg tattcaaaat
    13921 aatttaaggc agttatctaa aattgcagag cagtctcaag atagtcaagc ctacagagct
    13981 atggactata gcagaaggtt agtttcacat tatgaaaagc agttaacgcg ttaccacaag
    14041 aaaaagaaac ggaaattatt atctaaggga gcttaatgga taaaaggaga attaggaacg
    14101 taattaaaca agtctttttg tctgaagaag aaaatcaaaa actgttagag aaaatgaagc
    14161 aagatggctt cacaaacttt tctctttttg ctagaaagca attattaaaa cctgattttg
    14221 aaacttggct agttagtttt ccagaatatc agccgctgac tggcaggtta ctatctgttg
    14281 gtagaacaat taatggcatc gctaaaagcg caacacagtt tggaaaaatt tcccaacatg
    14341 atttgatgga attaggtcag ttgatggagg aacttgtaga actggtagag aaacaagtga
    14401 aggaagacaa gcaacgaata gccaagaagt gatagtcgtt cagtcatttt ggtagaatag
    14461 ttttaaataa aacaacaaaa acgctgatgg tagtcagcgt tttttagcat gtaattgtaa
    14521 aaaatccttg tacggacaat gtgcggcacc gtataaagta cgggaaatca ctaaaaatgg
    14581 agttaggtct ttgcgagctc agatagtgta tacacactat cgtaaaaata gaaccatcag
    14641 taaaggtcag actgacactt tttgattgat gcttatattt tattttgggg caaagcccca
    14701 aaccccttga gaaaacgtgt gagaagtagg gaaaaatggt ataatagaaa tattaaagac
    14761 tgtgaggatt tgaagatgtc agaacaagca caaaggcaag agttgcaccg caaaatctgg
    14821 gcaatcgcag atgatgtccg tggtgcggta gatggttggg atttcaaaca atatattttg
    14881 ggaatccttt tttaccgttt tatcagtgaa aatttcaaga cttatatcga gggtggtgag
    14941 gacttcaact atgaggagat tccggatgaa gtaatcacac ctgaggttaa ggatgatgcg
    15001 attaagacaa aggggtactt tattatgcct gcgcagcttt tttccaatgt tgtgaaaaca
    15061 gctcgtagta atgacaactt aaatacggaa ctcaaggata tttttgatgc cattgaggcg
    15121 agtgctatgg gttatgccag tgaaaatgat attaaaggtc tttttgatga cgtagacacc
    15181 agaagtaata agctaggaag taccgtccca gagcgtaatg aacgcttagc ccttatccta
    15241 gaaggtattg ccagccttga ttttggtagt ttcgaggaca atcatatcga cctttttggc
    15301 gatgcctatg agtttctgat ttctaactac gcttctaacg ccgggaaatc aggcggagag
    15361 tttttcacac cgcagagcgt gtcacggctc ctagcacgta tcgtcatgtt aggcaaggat
    15421 gaaaagaaca aaatcaataa gatttatgac cctgcttgtg gttctggttc tctcttgctt
    15481 caagccaaaa aacaatttac ggagcatatt atcgaggatg gtttttatgg tcaggaaatc
    15541 aacatgacca cctacaactt ggctcggatg aatatgttcc ttcataatat caactacgac
    15601 aagtttagca ttgagcgtgg caatacgctg ctggacccta agcatggcaa tgataagccc
    15661 tttgatgcta tcgtgtccaa cccgccttat tcaatcaagt gggttggtag cgatgacccg
    15721 acgctaatta atgatgaccg ttttgcacca gcggggattc tggcacccaa gtctaaagcg
    15781 gattttgctt ttatcatgca tagcctttct tatttgtcca ataaaggcag agcggctatt
    15841 gtgaccttcc ctgggatttt ttatcgtggt ggagcggagc aaaagattcg tcagtatttg
    15901 gtagacggaa actttgtcga aactgttatc caattgccgg ataatctcct ttttgggacg
    15961 tctatcgcta cctgtatcct tattcttgct aagaataagc cgacaacaga tgttctcttc
    16021 attgacgcta gccagcagtt caaaaaagaa accaataaca atgtcttgac agaagagaac
    16081 atcgagaaaa ttctgaaaag tgttgagcat aagaataatg aagagtattt tgctcagctc
    16141 atttcccaag aaaaaattgt ggaagctgac tacaatctct ctgtatctac ctacgtggaa
    16201 aaagaggata cgcgtgagaa gattaatatt gatgtattaa acaaagaaat tgctgagacc
    16261 gtgaaaaata ttgaccgatt gcgggcagag attgataaga ttgtcgagga gttgagctga
    16321 tatgacctac attgatgaga tgattaaaga gctttgtcct gacggagtgg agtggaaaga
    16381 gttgggtgaa gtcgttgact acgaacagcc aacaaagtat atcgtaaaat ctaaggaata
    16441 cagcgatgat tattccattc cagttttgac agcaggtcag acatttattc ttggatacac
    16501 aaatgaagta actggtattt atccagcaag taaggaacat ccagttatta ttttcgatga
    16561 ctttacgaca gctagaaagt gggtggattt tgaatttaaa gttaagtcct cggcgatgaa
    16621 actactctct atcaagtcag accgtcaaga tgatgtttca ataaggtatg tttggcacta
    16681 tttaggaaca ataaaataca caccagaaca gcacgcacga cagtggatag ggactttttc
    16741 taaatttaaa atcccccttc ccccactaga aattcaaggg gagatagtta aaatacttga
    16801 caaattcacg gaacatgtta cagaattgac cgcagaattg accgcagaat tgacctttcg
    16861 acagaaacaa tattcttatt ttagagataa gctcctaagt tttgatgatg aaagtatggg
    16921 aggggcgaac gataaggttt acactgtcca gtggaaaacg ctgggggagg tggtgaattt
    16981 taggagaggg tctttccctc agccttacac agatatgtcg ttctatggtg gagaagatgc
    17041 ccaaccattt gttcaagttg tagatgttgc tgatgaagga tttagactga atactaaaac
    17101 gaaaaaaaca atttctcaaa aagctattcc aaaaagtgtt tttgtaccta agggaaccgt
    17161 tatcgttacc ttgcaaggca ccctaggaag ggtagcggtt acccagtatg atgcttatgt
    17221 cgatagaacg ttagcaattt ttgacggtta taagcaagaa gttgataaac gctatttcgc
    17281 acaccaattg aagtttattt ttgacagaga aaaagaattt gctagaggaa gtactctgaa
    17341 aacaataaca aaacaagaat tctcgaattt caaaatccca gtccctcctc tggatattca
    17401 gcgtcgtatt gtccaagttt tggataattt tgatacggtt tgtaatgacc taaatatcgg
    17461 gctacctaag gagattgagc ttcatcagaa acagtatgcc tattttagag acaaactctt
    17521 gaccttcacc gccgaaggcg tgtatactga cagtacagta cagacaagac ctaattaggc
    17581 tcttgacttg ggtttttgga ccgattaagg ttgagttggg ggctgtctgc gatgtggtgc
    17641 gtgggaatgg tttgcaaaag aaggattttg ttaatgaggg ttatcctgtt attcattatg
    17701 gacaaatcta taccttctat ggattgagtg ctcgcgtgac gaaatctttt gtgtcaccag
    17761 aagttggtca aaaattgaaa aaagctaaaa ctggtgatgt gattgtagct actacttctg
    17821 aaaatattga agatgttggt aaagcacttg tttgggaagg tgctgaagat gtttgtattg
    17881 gtggacactc ttgtgtattg cacacggaac aaaactcgaa gtacttgctt tattattttc
    17941 agacaactgt gtttcaaaag caaaaggaaa agttagtgat aggaactaaa gtgattgaac
    18001 tgtatcctaa aaatttagaa aaggcgatta ttattctccc acctgtatac gaacaagggc
    18061 gtatcgtctc cattcttgac aaatttgata cactaacttc tgaccttacc caaggtcttc
    18121 cgaaagaaat tgagcaacga cagaaacagt atgagtattg gcgggattta ctacttaact
    18181 ttccgtagga ggaagaatag atatgggaaa tgatatcaaa tttgaaaatt tagaacagat
    18241 ttcggataat attatttcta gtaataagaa agttcatttg ctatatgcct ataatgctac
    18301 tgggaaaact aggctttcta tggaattgaa aaataaggta aatgagactg atagtgatgg
    18361 taatagcatt aagcacattt tatatttcaa ttcatatacg gaggatcttt ttacgtggga
    18421 taatgatttg gaaaacgatg aagatcgata tttgatttat gataaacgaa cttattttgg
    18481 aaatttcctt gaagagcaac aacttttcga acgtgctgta gacaattttc aaaagtatgt
    18541 tggtagatct attgatattg agttccaaga tgttattgaa acagttaaag atgagttcgg
    18601 aaatgttcaa aaagataata ggggtgaggc actaacaatt agtaataaaa agagtataag
    18661 atttaaagta gatgggcata caataaaggt gtctagagga gaagagagga tttttgtttg
    18721 gtcagttttc ttaacgctcc ttgaaattat tattgaagat ttgactgagt ctgctgatac
    18781 ctcagaattt tcaaaaatga actatatcta tattgacgat cctatatctt ctttggatga
    18841 tactaatatt attaatgctg caatttattt gagtgatgtt ataggtagtg ctgaaaatac
    18901 tgatttgaaa tttgtcgtct ctactcatca agcattattt tataatgtac tttataatga
    18961 aatccgattt gatagaagaa tcaagaaaaa ggttttttac gtcatgaaag ctactgatga
    19021 aattgaggat gagaaacaat ttaaatattt gttgacagat gttgaagggg attctccatt
    19081 tggatatcat ctcagagtga gagaagaatt gagaaaagca attcaagatg aacaggtaga
    19141 gaaattccat tttgctcttt ttagaaacct agttgaaaaa acagcaacat ttttaggata
    19201 tggacgatgg gaaaatatct tgttaggttt agatgttgct ggacatgtta taacatctga
    19261 aaatattaaa ctctatacac aactgattga tttatacact cataataggc atgctgattt
    19321 agaatataga gaattgcctc cccaagagaa aaatactctt ataaatttat ttaatagctt
    19381 tgattcaatc tatcgattta aagaggacta actatgactg aaatcatcca aacagatact
    19441 attttagagg ctaagaactt cattgtactg gaaaaataca ccaagttgga aaagcctagc
    19501 acctatcaga cggaagcaga cttggagcga gagctggtta gcgatttgcg gcagcaggga
    19561 tacgagtacc tcaacaatct gacgacccca gaagctctct tagataacct aaagacccag
    19621 atggaagccc ttaatggcgt ggttttttct gaggcagaat ggctgcgttt tttagaggag
    19681 tacctcaata agcctagtga tggtttgatt gaccgcaccc gaaagctcca cgataaccac
    19741 atctacgact ttatctttga cgatgggcat atccaaaata tttatctctg ggataagaaa
    19801 aatatcagtc gaaataagct tcaggtcatt aaccaaatgt ctcaagttgg gacttcaagt
    19861 aaccgttatg atgtgaccat tttggttaat gggctaccct tagtacaaat tgagcttaaa
    19921 aagcgtgggg tggctattcg tgaggctttc aaccaggttc accgttacag taaggaaagc
    19981 tttaatgagg aaaattcgct cttcaagtat ctccagattt ttgtcatttc aaatgggacg
    20041 gatactcgct attttgctaa taccactaag cgagagaaaa attcttttga ctttaccatg
    20101 aattgggcac taaaaaataa tgagccaatc aaggatttga aggattttac agcgaccttc
    20161 ttcagtcagc agacactctt aaacattctc atcaactact cagtttttga tactagtgat
    20221 accctcctaa tcatgcgtcc ctatcagatt gctgcgacgg agcgcatcat ctggaagatt
    20281 cgttcggcca ttgatagcaa aatcaagagt ggtcctgaga ctggcggcta tatctggcat
    20341 acgacggggt ctggtaagac cttgaccagt tttaaggctg cgagactggc gactgagatg
    20401 gataaagtgg acaaggtttt ctttgtggtt gataggaaag acttggacta ccagactatg
    20461 aaagaatacc agcgtttttc acctgactca gttaatgggt caaatagcac agctggactt
    20521 aaacgcaata tcgaaaaaga tgacaataag attgttgtga cgacgattca aaagctcaat
    20581 aactttatgt ctagtgaagc acagcatgag atttacaaca agcaagtggt ctttatcttt
    20641 gacgaatgcc actgttcaca gtttggcgag gctcaaaagc gcttaaaaca aaagtttaag
    20701 aagtattgtc agtttggttt tacaggcacg ccgattaaag ttgaaaatgc tttaggcagt
    20761 gagacgacag cttctgtatt cggtcgggag cttcatgcat acgtcattac tgatgctatc
    20821 cgtgaccaaa aggtgttgaa atttaaggtg gattataatg atgttcgtcc acagtttaag
    20881 tcgttagaaa ctgagcaaga tttagggaaa ttatctgctg ctgaaaataa aaaagcccta
    20941 cttcatccaa cacggattac agagatttcg gcttatattt tagaacattt taatcaaaag
    21001 acacataggc aaaacggtaa aggatttaac gctatgtttg ctgtgtcaag tgtcgaggcg
    21061 gccaaggctt actaccaaga gttgcaagac caacaagctg gaaaagctaa accattgaag
    21121 attgcaacca tcttctctta tgcagcaaat gaggagcagg ctgcgattgg ggagattgat
    21181 gacgagactt tcagccctgc tgacttgtca gatattagta gtaaggaatt tttgagcgga
    21241 gcgatttccg attataatcg cctttttcag actaatttta gtatcaatgg caatgagttt
    21301 caaaactatt accgtgattt agctaagcga gttaagtctg gagaagtgga tttgctgatt
    21361 gtcgttggta tgtttttgac tggttttgat gcaccaacct tgaatactct ttttgtggat
    21421 aaaaacttgc gttatcatgg gcttattcag gctttttctc ggacgaatcg gatttataat
    21481 gcgacaaaga catttggaaa tattgtaact ttccgtgatt tggagaaggc tacgacggat
    21541 gctattaagt tgttcgggaa gacggagacg gctgatattc tgttagagcg ctcttacgag
    21601 gactacatga atggctacat tgaggctggt caagagcaaa aaggatattt ggaagtcgta
    21661 aaagaattgc aggagagatt tccagatcca acgactatta tcaaagaaag tgataagaaa
    21721 gaatttgtga ccttgtttgg tcagttcttg cgcttggata atatcttgca gaactatgat
    21781 gatttcatga gtttgcaggc tttgcaagag ttagatgtta cagatataga ggctttggca
    21841 gatttcaaag gacgttttca tttggatgac gaagcagttg cagtactctc tcaactggac
    21901 atcccaagtg ttcgtgagat tcaagattat cgctccgctt acaatgatat caagtcttgg
    21961 tatgacaatg agcggcgtaa tcagcagaat aacgattccg aaatcgactg ggatgcggtt
    22021 gtctttgaag tggagttgtt gaaatcacag gaaatcaatc tggactatat tctggaattg
    22081 atttttgaaa ccaaccaaaa ggtatctgac aaggatcaac tcattgaaga aattacacga
    22141 actatccgtg ctagtctggg tcagagagct aaggaaagtt tgatcgtgga ttttatcaat
    22201 gccagtgact tggacagttt ttctgagaag tcagatatct tggagcaatt ttatacattt
    22261 gcccgtcaaa aacaaaaaga agcagtggct aatttgattg agactgaggg attgaatgta
    22321 gagagtgcta gccgctatat tcagatgtca ctcaaacgag agtatgccag tgaaaatggt
    22381 aatgctctca atgaagcact tcctaagatg agtccgctca atcctcaata tcgtaccaaa
    22441 aagcagatgg tgtttgaaaa aattgtggat ttggtggaga tatttaaggg gattggtgga
    22501 gaaatttaat tattattatt tcttctagat atagaagaga taaactttaa attagagctt
    22561 gaaattttaa gaaatattaa ggcatcatat cagtagtata aaaagctgac ttataattta
    22621 tttggaaacg acagttaatc ctaaaatacg atgcttgata tggaggaggc ttaaacttgg
    22681 aaaataaaaa ggatttaatt caaaccttag cctactacca attctcacta gaaaaccaat
    22741 acttggatag aaaatcagca cgaaagaagc cgcaagaatt actcaagcat ctgattgctt
    22801 ttgccaatgc ggacggcggt cagttggtta ttggtattga agatgagaag caggacaata
    22861 ttatcactgg tttcaaggat ggcagagctt atcccataga cgatttcaaa aaaattgacc
    22921 atgagatgcg ggagactcct ctggatttgt ctttagagga aatccctgtg ctaaatcata
    22981 agggagaaga tgacctgatt ttggttattt ctgttgaatt atcgtcgaac cgagtgattg
    23041 ctgcgcctaa tgatgaggtt tatctgcgtc agggcgatga atcggttaaa ttaagctatg
    23101 agcaacgtac tcagcttagc tatgataagg gccaacgttt ctttgaagat gaagtggtac
    23161 ctgatgcgac cttggaagat attgatgatg ggttagtcca ggacttcaaa aatcggtttg
    23221 atatttcaga gcgctccatg gaagaagttc ttaaagcaag acgattcttg gttaatggta
    23281 aattaactaa ggcagcgatt ctactctttg ccaaatatcc atcagcgttt tttccacaag
    23341 ctcgtgttcg ttttcaacgg tttgacggga cggatatggg aacaggcagt agctttaatg
    23401 ttattaaaga agtaactttt gatgatgctc tgcccacctt aattatcaaa gtgcgagatt
    23461 ttatccgtac tcagctgcgt gaatttcagt acttagacga taatgggcaa ttccagattt
    23521 tgcctgagta tcctgaattt gcttggtttg agggtgttgt caatgcggtg actcaccgtg
    23581 attactctgt ctatggggat cacattcgtg tactcatgtt tgatgataga ctggagattc
    23641 atagcccagg gaaattacca aatatcgtta ccgttgacaa tatcaagcat gaatgttttt
    23701 ctagaaatcc tcggattgcg agaaccctga ctgaatttgg atgggttcgt gagatgaatg
    23761 aaggagtgaa gcgtatctat tctgagatgg aatcagcttt tcttcatgaa cctaaatatt
    23821 tagaaccagg taataaggta gttttgaccc ttgaaaataa catcgtgagt cgacatctcc
    23881 gaacacgaga tagtttggaa aaacaatttt ctgattttgg aaatctgact gcagatgaac
    23941 aagctatcgt tcactacatg tataattctg gcgataaaat gacaacagca aaggcgattg
    24001 agttgacagg gagaagtcgt tcgtttgttg tcaaaatgct acatcatctt cgtgatttag
    24061 aaatcatcac ttggtttggt tcaagtaaaa atgaccgtaa tcaatattat cttttagttg
    24121 ataaatgatt gcagccagga tacttattag taataagaat acagtagaat acagaaaaag
    24181 tggtgttcca taaaatattg atcaccactt ttgattat
//
LOCUS       DARYXZ010000034        23221 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYXZ010000034 DARYXZ010000000
VERSION     DARYXZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23221
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..351
                     /locus_tag="TV186_001268"
     CDS             <1..351
                     /locus_tag="TV186_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1532662.1"
                     /translation="RGEQGPKGDRGEQGPKGDRGEQGPKGERGEQGPKGDRGEQGPKK
                     EPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLPSTGDTSQSFVAAALGF
                     IASAGLLVFKRKKN"
     gene            877..1767
                     /gene="rapZ"
                     /locus_tag="TV186_001269"
     CDS             877..1767
                     /gene="rapZ"
                     /locus_tag="TV186_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL1532663.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            1764..2741
                     /locus_tag="TV186_001270"
     CDS             1764..2741
                     /locus_tag="TV186_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL1532664.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            2738..3649
                     /gene="whiA"
                     /locus_tag="TV186_001271"
     CDS             2738..3649
                     /gene="whiA"
                     /locus_tag="TV186_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL1532665.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            4009..5406
                     /locus_tag="TV186_001272"
     CDS             4009..5406
                     /locus_tag="TV186_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL1532666.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            5646..7196
                     /locus_tag="TV186_001273"
     CDS             5646..7196
                     /locus_tag="TV186_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL1532667.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
     gene            7467..8195
                     /locus_tag="TV186_001274"
     CDS             7467..8195
                     /locus_tag="TV186_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1532668.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            8207..9382
                     /locus_tag="TV186_001275"
     CDS             8207..9382
                     /locus_tag="TV186_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL1532669.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            9392..10387
                     /gene="lacD"
                     /locus_tag="TV186_001276"
     CDS             9392..10387
                     /gene="lacD"
                     /locus_tag="TV186_001276"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1532670.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(10429..11148)
                     /locus_tag="TV186_001277"
     CDS             complement(10429..11148)
                     /locus_tag="TV186_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1532671.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            11288..13051
                     /locus_tag="TV186_001278"
     CDS             11288..13051
                     /locus_tag="TV186_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1532672.1"
                     /translation="MKQFCIKEQFYLDGKPFKILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDDVFVTGNFGSNASKQF
                     ASMQDFFQAHQKQWPLMCMEFWLGWFNRWNEPIIRRDSKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQERLKECYPQLS
                     FAEPMISSTMALESIKLSARVSLFKTIKNVSAIKKSFYPCNMEELDQPTGYLLYRTHL
                     ARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEGETTQLDILVENMG
                     RVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHFPLDFQELDWIDFSAGWTDEVPGFY
                     AYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRFWKVGPTLSLYIPKGLLKQGQNRLL
                     IFETEGQFSESIRLTKEPIYK"
     gene            13069..13554
                     /locus_tag="TV186_001279"
     CDS             13069..13554
                     /locus_tag="TV186_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1532673.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            13600..14481
                     /locus_tag="TV186_001280"
     CDS             13600..14481
                     /locus_tag="TV186_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1532674.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            14468..15286
                     /locus_tag="TV186_001281"
     CDS             14468..15286
                     /locus_tag="TV186_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL1532675.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            15290..15694
                     /locus_tag="TV186_001282"
     CDS             15290..15694
                     /locus_tag="TV186_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL1532676.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(15798..16058)
                     /locus_tag="TV186_001283"
     CDS             complement(15798..16058)
                     /locus_tag="TV186_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL1532677.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(16183..17115)
                     /locus_tag="TV186_001284"
     CDS             complement(16183..17115)
                     /locus_tag="TV186_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL1532678.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(17125..17553)
                     /locus_tag="TV186_001285"
     CDS             complement(17125..17553)
                     /locus_tag="TV186_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1532679.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            17811..18836
                     /locus_tag="TV186_001286"
     CDS             17811..18836
                     /locus_tag="TV186_001286"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL1532680.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            18897..19343
                     /locus_tag="TV186_001287"
     CDS             18897..19343
                     /locus_tag="TV186_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL1532681.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            19672..19965
                     /locus_tag="TV186_001288"
     CDS             19672..19965
                     /locus_tag="TV186_001288"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL1532682.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            19946..21177
                     /locus_tag="TV186_001289"
                     /pseudo
     CDS             19946..21177
                     /locus_tag="TV186_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            21323..21670
                     /gene="rplS"
                     /locus_tag="TV186_001290"
     CDS             21323..21670
                     /gene="rplS"
                     /locus_tag="TV186_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL1532683.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            22185..22256
                     /locus_tag="TV186_001291"
     tRNA            22185..22256
                     /locus_tag="TV186_001291"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22218..22220,aa:Arg,seq:cct)
     gene            complement(22380..23183)
                     /locus_tag="TV186_001292"
     CDS             complement(22380..23183)
                     /locus_tag="TV186_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1532684.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
BASE COUNT         6578 a         4463 c         5396 g         6784 t
ORIGIN      
        1 cgtggcgagc aaggaccaaa aggtgatcgt ggcgaacaag gaccaaaggg tgatcgtggc
       61 gagcaaggac caaaaggtga acgcggtgag caaggaccaa aaggcgatcg tggcgagcaa
      121 ggtccaaaga aggagccaga aaaagacacc aagccatcag tgccaaaggc accagataat
      181 atggctgcac caaaggctcc ggagaagaag aaccctaaag caccggctcc taagtcagct
      241 ccaaaggcat cattgccatc aacaggagac actagccaat catttgttgc agcagccctt
      301 ggctttatcg ctagcgcggg cttgctagtc ttcaaaagaa agaaaaacta agctagctaa
      361 agactgtaaa caagcctcaa ctgttacagc aagcctcttt gacatcttgc agataagagg
      421 atttcttagc gaatgaagtg tgtctaaagt cagatactct gctggactag cagtagctga
      481 tctccctgaa aatcagttat gctaaagcat tgagccttag ttgcaaggct taggtgtgac
      541 cttccaaagg aagctgcttt tgcctgtatc actttaggaa gatatctaaa agagacactt
      601 ttttcacgct gaagctaagc tagcttttcc tatgacaaat atcctataac aataaactcc
      661 aaacaaaaga gaggtcaaat ggtacctctc ttttacttag ctttaggatt gatagattct
      721 aaaggcttcc ttgtttcttg atcaagaagt ccttactgat agagtctgtc ttagccgggc
      781 ttatatggta taatacctaa tggagataag aaaagtcctt aacaaataga gtttcatcta
      841 ttgttacagg agcaaccaag tgaaaggaga tgctacatgt cagataaaca aatcaatttg
      901 gttattgtta caggaatgag tggcgccggc aaaacagttg ccattcaatc atttgaggat
      961 ttggggtatt ttactgttga taacatgcca ccagctttag tgcctaaatt tttagagctg
     1021 cttgagagga ccaatgaaac ccaaaaggtt gctctggtag tggatatgcg cagcagacgc
     1081 tttttcaagg agattaactc tatcttagat catattgagc taaatgccaa cctcaagcta
     1141 cggatcctct ttcttgatgc gactgatagt gagctagtgt cacgctataa ggaaactaga
     1201 agaagtcacc ctctggctgc tgatggtcgg gtgcttgatg ggattcgacg agaaagagag
     1261 ctgttagtcc cgcttaagag catgagtcag catgtggtca ataccaccga tctaacccca
     1321 agacagctgc gtaaggtgat ttcggatcag ttttcaagcg agtcagacca agcctcattt
     1381 agaattgagg tgatgagctt tggctttaaa tatggcctcc ccttagatgc ggaccttgtc
     1441 tttgatgtgc gctttttgcc taatccttat tatcaggtgg cgctaagaga gcagacaggg
     1501 cttgatcagg ctgtttttga ttatgtgatg actcatcaag agtcagaggc cttttataat
     1561 catttgttag gcttgattgt tcctattttg cctgcttatc aaaaggaagg caaatcagtg
     1621 ctaaccattg ctattggctg tacaggtggt cagcatagaa gtgtcgcctt tgcccatcgc
     1681 ttggcccaag acttgacagc agactggccg ctgcatgaga gtcatcggga catcaatcgt
     1741 cgtaaggaaa cggtaaatcg ctcatgagaa atcctaaaat aacggtgata ggaggaggaa
     1801 caggtattcc tgttatccta aaaagccttc gcaaggaggc ggttgacatt actgcggtgg
     1861 tcactgttgc tgatgatggt gggtcatctg gtaagctgcg caatgccatg cagcttaccc
     1921 cgccaggtga tttgcgcaac gtcttgttgg ccatgagtga catgcctaag ttttatgagc
     1981 gtgtgtttca gtatcgtttt aatgaggcag atggtgctct agctggtcat cctctaggca
     2041 atttaattat cgcaggtatt tctgagatgc agggatccac ctataacgct attcagattt
     2101 tgacgaaatt tttccatatc accggcaaga tttttccctc aagcgagcag cccttgacac
     2161 tgcatgctgt ctttaaggac ggtcatgagg tgtcaggaga aagctctatt gccagctacc
     2221 aaggcatgat tgaccatgtc tatgtgacca atacctacaa tgatgacctg ccaaaggcca
     2281 gtcgtaaggt ggttgaggcc attctccaaa gtgatatgat tgtgcttggt cctggttcct
     2341 tgtttacctc tattttgccc aatcttgtaa ttccagagat caaagaagcc ctgagagtaa
     2401 ccaaggcaga ggtggtttat atttgtaaca ttatgaccca gtacggtgag acagagcaat
     2461 tttccgatgc ggatcatgtt gcggttttaa atcagcatct gggcagggac ttaattgaca
     2521 ctgttttggt taatgttgag caggtgccaa aaagctatat gaattccaac caatttgacg
     2581 aatatctggt ccaagtagag catgactttg caggtctgtg taagaccgca aagcgtatca
     2641 tctcgtctaa ttttctgcgt ttggagaatg gcggagcctt tcatgacggg cacttggttg
     2701 tagaagaatt aatgaaccta gttaggataa ccaagctatg agttttacga caactgttaa
     2761 agaagaattg attcatttat ctgcttctga tcaaacagaa ttatcagcaa tcatcaagct
     2821 ggctggtagc ctaggcttgg ctaatcagag cttgaatttg tctatcacaa ctgaaaacgc
     2881 taagattgct cgctacatct atgcgcttat cgaagacacc tatcatatca ttccagaaat
     2941 caggtaccat caaaagacca acttgaaaaa aaatcgtgtc tatacggttt atttggataa
     3001 gcaggtggat aagctcttag cagatttaaa gctggcagat tctttttttg gcattgagac
     3061 aggtattgag cagcaggtca tgtcagatga tgatgctggt cgggcctatc tcaagggtgc
     3121 ttttttagcg gcagggactg taagggatcc agaatccggc aagtatcagc tagagatcta
     3181 ctctgtctat ctagaccatg ctcaggattt ggcccagctc atgcacaaat tcatgctaga
     3241 tgccaaggtt atcgagagaa aaaatggtgc agtaacctat ttgcaaaagg ctgaggacat
     3301 catggatttt ctcattatta ttggtgccat gtcgtgtaag gaggagtttg aggctgttaa
     3361 gcttttgcgt gaggcgagaa atgacatcaa tcgggccaat aatgcagaga ctgctaatat
     3421 tgctaaaacc atcaccgcca gcatgagaac cattaataat attatcaaaa tcatggatac
     3481 gattggctta gacagcctgc cagttgagct gcagcagatt gcccagatga gagtagccaa
     3541 cccagactat tctcttcaac aaatcgcaga ttcgcttgac tttgccatca ctaagagtgg
     3601 ggtcaaccat cgcctgcgaa aaatcaataa gctggcagag gatttataaa gacagcttag
     3661 cctttttcag gctgataaaa aagggggtaa ggtgatacga acaagccgcc ttttaaggca
     3721 tgccttgttg agctttctct aggctgttga tggagtgatc tcaaggcgct tttgttactg
     3781 tcattccaac aggctatctg attttgggat gacttcttac taataagctt ttctaatggc
     3841 tggctgacaa cgattagcga tatagttaag gcttatcgtg attcaacaag aggctttagt
     3901 ctcttttttg cttgtcagaa ttattttttt aggcttttct tacaaatgag aggacaatgt
     3961 gacaatctgt ggtatgatat tagtaatgaa tacaaaggag aacaaatcat gtcatgcaca
     4021 actattcttg tcggtaaaaa agcgacctat gatggatcaa caatcgttgc tcgtacagag
     4081 gattcacaaa atggggaatt tacccctaaa aaaatgacag ttgttagacc aaaagaccaa
     4141 cctagacact atcaatctgt cttgtctagc tttagcatgg agctgccgga tcagccgatg
     4201 gcttatacct cggtgcctga tgccctagga aaggacggta tctggggaga agcaggtgtc
     4261 aataccctca atgttgctat gtcagcaact gagaccatta cttcaaatgc tcgcgttctt
     4321 ggagcagatc ctcttgtttc ctctggtatt ggagaagagg acatgctgac cttggtgctt
     4381 ccttatattc ggtctgcaag agagggtgtt cttcgtttgg gagctatcct agaagcatac
     4441 ggtacctatg aggctaacgg tgttgccttt tctgatgagc atgagatttg gtggctggaa
     4501 acaataggtg gtcatcattg gattgcaagg cgcgttcctg atgatgctta tgtcactaat
     4561 cccaaccagt ttggccttga tcactttgaa tttaacaatc cagaggaata cctgtgttcc
     4621 aaggatttaa aggactttat tgccaaatat catctagatt tgacctatag caacgagcat
     4681 tttaaccctc gctacgcctt tggtagccaa agagataagg atcgccatta caatacacca
     4741 cgcgcttgga ttatgcagca atactttaat ccggagtttc tgcaggatcc gcgcagcttt
     4801 gaacttcctt ggtgccaaag acctgatcgc aaggtgacca ttgaagacgt taagtacgtg
     4861 cttagcaatc attatcagga caccccttat gatccttacg gcccagaggg aacgccgact
     4921 agtcgaaaat cctttaggcc gattggtatt aaccgtacga gtcaaactgc tattttacat
     4981 atccgtccca acaagcctaa ggaaattgct gccattcagt ggatggccta tggttcgatg
     5041 ccctttaata caatcgttcc gctattcacc caggtcaaga ccattccaga ttattttgca
     5101 aacactgttg aaaatgtttc cacagacaat ttctattgga ccaatcgctt gattgcagcc
     5161 ctggctgatc ctcacttcaa gcaccatgaa gcagatttgg aggactatct cgaaaaaaca
     5221 atggccaagg gtcatgccat gctgcatgct gttgaagcag cgctagtaaa aggtcagccg
     5281 gttgacctag aagaggccaa ccaaggcatg agtgatgaca ttcaggcaga tacacaggct
     5341 ctgctcaata agatcctctt tgatgctagc aatctcatga ccaaccgctt tagcctaagc
     5401 gactaagtaa tctcaatagt caaacgagct catatcatta tagatatggg ctcttagctt
     5461 gaaaaggata gtagagcggt cttatagtca gactaattaa tggtaacgat gagtccagtt
     5521 aaggtaaaaa aagagcactt agctaatgca aaaaaagtaa aaaacttgca aaagaatgat
     5581 attgtgttat acttaaccag taaatattaa gagctatttg cgatatgata tatagaggag
     5641 gaatcatgaa aaagaagtat cttttaatga tgagtgtgct cggtgtcttt tttgcgggac
     5701 agatcagtca agcaaaacag gtcctagcag atagtaaggt caaaattgtt accaccttct
     5761 atcctgttta tgaatttacc aaaggcgttg tcggaggtga gggaaatgtg tctatgctga
     5821 tgaaagcagg aacagagcct catgattttg agccgtcaac aaaggacatc aaaaagatcc
     5881 aagatgccga tgcctttgtt tatatggacg ataatatgga aacttgggtc cctgatatga
     5941 agaaatcact gacttctaag aaggttacgg tgattaaggg aacaggagat atgctattgg
     6001 tagctggctc tggtcacagc cacgagcatg accatgacga tgccgataaa aagcatgatc
     6061 atgaccacga cgaggaagga cacagccatg cttttgaccc gcacgtatgg ttgtcacctt
     6121 atcgcagcat caccgttgtc gaaacaattc gtgatggtct atctaaggcc tatcctgaca
     6181 aggctgacca cttcaaatct aatgccgctg cttatattga aaagctcaag gaattagata
     6241 aggagtatag tgacgctttt tcagctgcca agcaaaagag ctttgtgact cagcacgcag
     6301 cctttggtta tatggcgctt gattatggct tgaaccaaat ctcaatcaat ggtgtcacac
     6361 cagatacgga gccttcagct aagcgcattg cagagctatc aaaatacgtc aaaaaatatg
     6421 acattaacta catttatttt gaagaaaatg cttcaagcaa ggttgccaaa accctagcca
     6481 aggaggctgg tgtcaaatca gctgtcctta gtccgcttga aggcctaact gaaaaggaca
     6541 tgaaggccgg caaggattac tttaccgtta tgcgtgaaaa cctcaaaacc ctacgcttaa
     6601 caactgatgt agaaggaaaa gaaattcttc cagaagagga taccactaaa actgtttata
     6661 atggctactt taaggataag caggtcaaag accgcaaatt gtctgattgg tctggtaact
     6721 ggcagtctgt ttacccattc cttcaagacg gtacattaga tcaggtatgg gactataagg
     6781 ctaaaaaatc taaaggaaaa atgaccgcag ctgaatacaa ggattattac accactggct
     6841 atcagacaga tgtcagtcat atcaagatta atggtaagaa aaataccatg acctttgttc
     6901 gtaatggtga aaataaaacc tttacttata agtacgtcgg taaaaagatt ttgacctatc
     6961 caaagggcaa tcgtggcgtg cgcttcatgt ttgaagctaa ggagccagac gctggtgaat
     7021 ttaaatatgt tcagttcagt gaccatgcta tcgcgccagg taaggcggag catttccacc
     7081 tatactgggg tggtgacagc caagaaaagc ttcacaaaga gctagagcat tggccaactt
     7141 actatgatgc ggacctatca ggtcgtgccg ttgcccaaga aatcaatgct cattaaccac
     7201 tcaaaagact aggcagttca atcggcctag ttttttcttg tcttagttgc tgtataggac
     7261 ctaaatgctg atagctggtc ttaagattta tttttaattt ttctaactat atttaggttg
     7321 tatttgtttg ttaataccaa atccattgtt ttagggatta tatagaatta atatgttaaa
     7381 tattttaata tttttcaaaa aagtattgac ttttagattg taatataata ttatttaagt
     7441 ggttataata agttagaggt gttagtatga taaaggaaca gccactctac ttacaaattg
     7501 ttgatgtatt agaggtcaaa attagaaata ccatgtcagc taatgataaa ttgttatcag
     7561 aacgagagct aagtgactta tttggtgtta gtcggataac cattagattg gcacttaagg
     7621 agctagagct gcgtgggctt atttacaaac agcagggcaa ggggacctat gtatcaggca
     7681 taaaggagcc tgctacagac ctgtcctcag cctatagctt taccgaagag atgaaaaagc
     7741 aaggtcgtaa gcctcaaaca gtcattcttt catttgaaaa aatcaagacc acagcttact
     7801 tgtctggtat gttagattta gatgttgata ctgatgtttt tgagctagag cgtctaagga
     7861 ttgcagatgg aaagccatta atgtttgagc gcacttatat acctgaaagg ggatttgagg
     7921 cgataacgat tgatttattg gaaaaaaagc ccttatatga tgtgtttgct gaggattttc
     7981 aggaagctat ccgattggct gatgaggagt tttacgctag tatcgctcta gattatgaag
     8041 caaagctatt agggatcaaa aagggggatc ctgtgctgca tattatgcgt aagacctata
     8101 atgagaaaaa taggctaatc gaatttacct ttagtattgc tagagcagac cagtttaggt
     8161 accgtatcca gcaccaccct aacaagaaga tataggaggt aaggaaatgt ttacaaaaac
     8221 acaagcagaa ctagagctac ttggcgcagc tatcaccact agagaaatca agcagcagcc
     8281 agagctatgg tcagaggtct ttgagtcttt tctgaagcaa aaaaaagacc tcttagcctt
     8341 ttttgacagg attattgaaa gcgctaacag aaacaaggta aaaattattt ttacaggagc
     8401 tggaacttct gaatacattg gcaataccat ttgtcattat ttggagatga ctggtgacag
     8461 ggaaaattat ttatattaca gcattgcttc cacagacctt gttgcagctc caagccagta
     8521 tctctttgaa gaggatacag tcgtgcttgt ttcctttgca agaagtggca atagtcctga
     8581 aagtgtcgct gctgttagtc ttgttaatca gctggtgtca aatccttatc atttggtgat
     8641 aacctgtgcc aaagaggggg ccttagctca aaatgctaag aaggacaaaa ggagctattt
     8701 attcttgctg cctgaggcct caaatgacgc tggctttgct atgacgggaa gctttagctg
     8761 catgatgcta gcggccttgt tgatttttga tcaagcgcat tcccttgagg agaaaaaatg
     8821 ctatttagat cagattgtag gtatggtggc agctattatt cagcaggagg ctgatttaca
     8881 aaagctggtt agcttagagt ttcaacgctt ggtttacctg ggatcaggag ccttagcggg
     8941 gcttacgcaa gaggctcaat tgaagatttt agaattaaca gctggcaaaa ttgcaacagt
     9001 ctatgactcc tcaatgggct ttaggcatgg tccaaagtca tttattgatg atcagacatt
     9061 ggttattggt tttgttagca atgatcctta tacgagaagg tatgaccttg atgttttaga
     9121 agagataaga gaggatgcta ttgctgttga tacggttgca ttacagcagc aaggaggtga
     9181 gggctttagt gggcattgct ttggcttaga ctcgtcaatg ctattgccag atgcttattt
     9241 ggcctttccg cttgttttta tcgcccaaac gcttgctttg ctgtcgtcta ttaaggttaa
     9301 taatttacca gatactcctt cggccacagg aacggttaac agggttgtcc aaggtgttaa
     9361 gatttatcac tattttaagt aggagaacaa gatgtaccat ttatcaaaag ctaagtatcg
     9421 tcttcttgaa aaggtcagtc gtaagggcat catttcggcc ttggcctttg atcaacgcgg
     9481 ggttttaaag cgcatgatgg cagcccacca agacacagag ccaactcctt ggcaaatcga
     9541 agccctaaag gctctggtat cagaggagct aaccccctat gcctcctcta tcctgctaga
     9601 ccctgaatat ggcctgccag ccaccaaggt gcgtgatgag aagtctggct tattattagc
     9661 ctatgaacaa accggctatg acacaaccac cactagccgc ctgccagatt gtctggtgga
     9721 ctggtcagtc aagcgcctca aggaggccgg agctgacgca gtgaagttct tgctgtacta
     9781 tgatgttgat ggtgatgagc gtattaacca acaaaagcag gcctatatcg agcgtatcgg
     9841 ctcagaatgt caggcagagg agataccatt tttccttgag ctattgacct atgatgaggc
     9901 gataacagac aatcagagtg tagcttttgc caagctaaag gcacacaagg ttaatgaggc
     9961 catgaaggtc ttttcaactg agcgctttgg ggttgatgtc ctaaaggtag aggttcctgt
    10021 caatatggcc tatgttgagg gctttgcaga gggtgaggtt gtttacagca aagaggaggc
    10081 tatgcaggcc tttcgtgacc aagaggcagc tagtcacttg ccctatattt atttgagtgc
    10141 gggtgtatca gctagtctgt ttcaagagac cttggttttt gcggcagagg caggagctag
    10201 gttcaatggt gtgctgtgtg gtagggccac ttggtcagga gcagtagcgg tgtacatgtc
    10261 agagggcgag gaggcagcgc gtcaatggct tcgcacagag ggttttgaaa atattgatcg
    10321 tctcaatcag gtgcttgaga aaacagccag cccttggaca acaaagctta ctcttgatga
    10381 agcctagtaa aggcatgata aaagcaatac taggacattg cttctgtatt attggtaatc
    10441 actggaggac aaggcgtact tgaaaaattg ccaatgcttg taggactcgg tgtactctag
    10501 aatacggcca ttatctgtcg accgagtgag cttggtttga aggacacaag gagtgttgtc
    10561 tatcatgttt aaaaatgtag cgacatcttt aggcatgtga tccgtcagct gtgtttgctg
    10621 ggtgaagctt tgtgatcgca tttgaatgtg aaaatccaaa aagaagcgct tataaagcga
    10681 ctggtaatca gctaaatcac gctcagggca cagcaggtaa tcatgaggaa tataagatag
    10741 ctggtataaa tagggctgct gattaatcgt tcgtgtacgg gagatggtgt agtaaaattc
    10801 cgttttatga agtttcaaga gatttagata gtagggatca tttcccttaa ctacactaag
    10861 gacagtcacc tcctcttttt gatccttaaa ggtacctaga taggaaaatt ggactagctg
    10921 ttcttttctg gtacgggtaa tgaaggttcc aagtccctgc cttcttctga taaagccttc
    10981 tttttctagt tctttaaggg ctcgaatgat ggttatggag ctaacatgaa agcgtttaat
    11041 cagctcggct tcggtataaa atttgtcccc ggtatggtag tggccattca gaatttggtt
    11101 ttgcaattct tctttgatta gtcggtactt tgggtatttg atggtcatag ttactcactc
    11161 aataattgtt tagtacgatt atagcaaaaa tagtaagctg atgtcatatc ttaccagtta
    11221 ttgctcagat agcttgtcaa tcagtcattg atcaaaggct gatggttaat gaataaaagg
    11281 agataatatg aagcaatttt gcataaagga gcagttttac cttgatggca agccgtttaa
    11341 gatattatca ggtgccattc attactttag aatagctcct gatagctggt ctagggtgct
    11401 ttatcagctg aaggccttag gctttaatac agtagaaacc tatattcctt ggaatatgca
    11461 tgagccaagg aagggacagt ttacctttga ggggattgca gatgttgagg catttttgga
    11521 tttggcacag gaatgtggcc tatatgctat tgtcagaccc tctccttata tctgtgctga
    11581 atgggagttt ggtggtttac cggcttggct attaactgaa aattgtaggc tcagatcaag
    11641 cgatgaggtc tttcttaagc atgtatcaga ttattatgat gtgttactac caaagctggt
    11701 gaagcgtcag ttagataatg gcggcaatat tctgatgttt cagcttgaaa atgagtatgg
    11761 ttcttatggt gaagaaaagg cttatttaag aaaattaaaa gagcttatgc ttgctaaagg
    11821 cattagtgcc cctctcttta cctcagatgg gccttggcca gccacgctag catcagggag
    11881 tctgattgac gatgatgttt ttgtgacagg caactttggg tcaaacgctt caaagcaatt
    11941 tgccagtatg caggattttt tccaagcaca tcaaaagcaa tggcctctga tgtgtatgga
    12001 attctggttg ggctggttta atcgctggaa tgagccaatc attcgaaggg actccaagga
    12061 agctgttgat gcaatcatgg aagctataga gctaggcagc attaaccttt atatgttttg
    12121 tggtggcact aattttggct ttatgaatgg ctcgtcagct cgtctgcaaa aggatttacc
    12181 acagataacc tcctatgatt acgacgcatt actagatgag gcagggaacc cgacaaagaa
    12241 atataccctg ctgcaagaac gtctcaagga gtgttaccct caattatcct ttgcagagcc
    12301 aatgatcagt tctacgatgg ccttagagtc tatcaagttg tcggcaaggg ttagtctttt
    12361 taagacaatc aaaaatgtaa gcgctatcaa gaaaagtttt tatccttgta atatggagga
    12421 gctagatcaa ccaacgggct acctactgta tagaacgcac ctcgctagac atagcaagga
    12481 ggagcggctc agggtcattg atgctagaga ccgcattcag ctctttttag atgaaaagca
    12541 cgtgaaaacc cagtatcagg aggaaatcgg tcaggatata ctgatacatc aagagggtga
    12601 gaccacacag cttgatattt tagtcgaaaa tatgggacgt gtcagctatg ggtacaagct
    12661 gacagcacca agccaacaaa aaggattagg cagaggctta atggctgact tgcattttgt
    12721 aggtgattgg gagcattttc cactagattt tcaagagctg gattggattg atttttctgc
    12781 aggttggacc gatgaggtgc caggatttta cgcctatgat tttgattgtc agcagccggc
    12841 agatacctac cttgatttga gtcaattcgg aaaaggaatt gcccttgtaa atggtgttaa
    12901 cctaggacgt ttttggaagg tcggtccaac attatcgctt tatattccta agggactatt
    12961 aaaacaaggt caaaatagac tgctgatatt tgaaacagaa gggcagttta gtgagtcaat
    13021 tcgtttaact aaggaaccaa tttataaata gataaaagga gaaaacttat gacaattgtt
    13081 gcagcacgta ttgacggccg gttaattcat ggtcaggtag ctaatctatg gacgacaaag
    13141 ctaaacatta gccgtatcat ggtggtcgat aatgaggtga ttagcaatga ccttgaaaaa
    13201 acagcactga agctagccac acctagcggt gttaaattat ctatcttatc tgttgaaaaa
    13261 gcagccaaca atattttgga agggcgctat gattctcaac gcttgttgat agtagccaga
    13321 aagccggata gctttttgga gctgattcaa aaaggggttg ctatttcaga gttaaatgtc
    13381 ggcaatatgt cacagacacc ggagactcgt ccagtaacgc gttctattaa cgttgtagac
    13441 gaggatatag aggcattcaa ggctatttca gccaaagggt gtcatctcat tgcccaaatg
    13501 gtgcctaatg atgccccagc agactttatg ccgctgttgg ataaggttga ttaagatgtg
    13561 tcaaatcaaa aacgaatctg tttcaggagg taaaagctta tgattcaatg gtggcaaatc
    13621 ctattattaa cactctactc agcttatcaa atattagatg agctaacaat tgtctcttct
    13681 gcaggctcac ctgtatttgc aggatttatt tcaggtatca tcatgggaga tgtgcaaacc
    13741 ggtctttgga ttggtggtag ccttcaattg atggtgcttg gtgttgggac ctttggagga
    13801 gcttcgcgta tcgatgcaac ctctggtgcg gttattgcga cagccttctc ggttgctcaa
    13861 ggcatagagc cagaattagc gatttcaacc attgcagttc cggtagcggc cttgctggtt
    13921 tatactgata ttctaggacg cttttcaacg accttctttg ctcaccgtat tgaccgccat
    13981 gttgaaaact ttaactaccg aggcatcgag cgtgattacc ttatgggagc tgtaccttgg
    14041 gccctatcac gtgctctgcc ggtattttta gcggtctctt taggtggtgg tgcggttgat
    14101 acagttgtta agttcattga ccattatgaa tggctagcaa atggtctaac tcttgcagga
    14161 aaaatgcttc caggcttggg ctttgcgatc ttgcttcact acctaccagt taaacgtaat
    14221 ctccattatc tggctttagg ttttggcttg acagcaatgc taacaaccat ttacaccaac
    14281 cttcaggtag ctggaggcgc ccttgcagga gtagccaagg atttcaatgc cgcaccattc
    14341 aaggggctgc caatgattgg tattgctatt attgggcttt ccttggcaac cctccattat
    14401 aaaaatggtc aacaagcacc tgtagctgaa caaaaacctg gggtatcaga aagtggggaa
    14461 attgaagatg acgaaatcta attataaatt aaccaaacag gattttaatc aaatcaataa
    14521 gcgcagcctg ttcacattcc aatggggctg gaactacgag cgtatgcagg gctctagcta
    14581 tctttacatg attttaccac agcttcgtaa gatttatggc gatggaactc cagagctaaa
    14641 agaaatgatg aagacgcaca cgcagttttt taacacatca aatttctttc atacgattat
    14701 cacaggaatt gacttggcgt tggaggaaaa tgaaggactt gcctcaaaag atgctgttaa
    14761 tgggattaaa acaggcttaa tggggccatt tgctccaatt ggtgattcgg tctttggctc
    14821 cttagtacca gctattatgg gctctatagc cgcaggtctt gctaaagaag gggtttggtc
    14881 agggattact ggtgtattga tgtgggtatg tactcagatg atcatcaatg tgtttcgttg
    14941 gaagcagctt gaaattgctt ataaagaagg tacaaagctc gtcaccacca tgcgtgataa
    15001 gctaactgct gtagtagatg cagcctcagt catgggagta ttcatggtag gggccttaat
    15061 tgcaacaatg attaattttc agtttaccgc agcacccaaa attggagaga aagttatcaa
    15121 tattcaagat ttaattgata ccatttttcc acgtctagtt ccagccttat ttaccggagg
    15181 tatcttctgg ctgctagggc gtaagggcat gtcaccaact aaggcaattg ttgtgattat
    15241 tttatttgcc ttagtgatgt cttatttcaa tattttagga gtatagctga tggcgcaaac
    15301 cttaattctc attagtcatg gagctttttg tcgagagcta aaacagagta cagaaatgat
    15361 tatggggcca caggacaata ttttaacagc agagctgcaa ccaaacgaag gtgccgatga
    15421 ctttaaagaa aagcttttaa ggctaattgc aggtttagat gacgtccttg tgtttgcaga
    15481 tttgatgggt ggaacaccct gtaacgttgc cagtcgtttg ttaatggaag gacatcagtt
    15541 tgagctgtac gcaggcatga atatgccaat ggtcattggt ttcattaatg cctgtttgat
    15601 cggtgaagcg tttgatttca aagcctttgc ctgtgacaat attcaccatg tcaataccat
    15661 tatttcagct ctagcagatg atgatgacga ctaaccaagc tcgcttattt gtcacgcacc
    15721 ttacggagcg aaacggacca agagccgcat aatcaaaaaa gacactgcca aatcttggca
    15781 gtgtctttgc tgtaagctta ttttgctgcg tttgcgtctt tgagaccgta tttcttgttg
    15841 aaacgatcca cacgtccatc ggcttgtgta aacttttgac gacctgtgta gaatgggtgt
    15901 gagtctgatg aaatttctac acgaacaaga gggtaagttt ccccttcaaa ctcaatggtt
    15961 tctttagagg tcttagttga accgctaagg aatttgtagc ctgtagttgt atcaaggaaa
    16021 acaactggac gataatctgg atgaatgtct tttctcatct taaaaaagtt cctttctgcc
    16081 atgatactgt ccgtatcata gttattaact actctagttt aacaaaagtt agtaagcttg
    16141 acaagctttt tctatcacta ttcatcaata agatgataag tcttatgtta agagatcaat
    16201 cagctcttgg tagatttgct cattttcctc taagcctgat gacgtggcac cgctagcaag
    16261 agggtgcccg cctccttgat gacgcttagc aataccattg atgacctttt ctttactgcg
    16321 catgcgtact cggtactggc catctggcag ctcaacaaag ataacccaag cctgcaccac
    16381 gtctattttt ccaggagcag agacaatcgc tgagctttct gccaagctaa taccaaagga
    16441 atttaggacc tcctggctaa gcagtaggcg ggctgcacca ctgtcatcta tatcaagctg
    16501 ctcaaaaaca tagccttgta gcttggcaat tttaagtgga aaggaatcca tctgcctcga
    16561 aatagcagca aagtcaaagg cataatttct taattggctt gcaatggcca gtgttttact
    16621 gcttgttgag gcatagagaa agcgtcctgt atctcccaca atgccagtat ataatagtct
    16681 agctgcctca tcagttaaag ccaagccttg gctaaaggca aattcagcaa taatctcact
    16741 agcacttgag gtcttggtgt caacgtagga gagatcacca tagacatcat cgttagggtg
    16801 atgatcaatt ttaatgaggc aagcgcccat tgtgtagcgc tcatcatcaa tgcgggggcg
    16861 attggcagtg tctgtaacaa tcactaaagc ttccttataa tcatcgtcgg acacctgatc
    16921 catgagacta atccaagcca gactaggctc atcaaagcct gttatcagga cctttttgtc
    16981 agggaaatta tgcctgataa tctctttaag tcctgcttgg ctccctagag catctggatc
    17041 ggggttttgg tgccgatgaa tgatgatggt ttgatagtgc ttaatgtgtt ctaaaatagt
    17101 ttgaaacgtt gtcataggta tcctttagtt tttgatcata tcaatgtgag gaatattgtc
    17161 ttccagataa atctcagaga ctgctttaaa cccaaatgag ctgtaaaaag gctcaagata
    17221 agcctgcgct tgagcgtaga cgggaagctt tggaaagtgc tgttgacaat aggctaaggc
    17281 ttgatgaact aagtcacgtc ctagtcctgt tcgccttgca ttttgtgcta ccagtactcg
    17341 tcccagcttt atgctattgt cagttgggat taagcgacag taggccctaa gctctgaatc
    17401 aacctgcttg aaaagatgga tagctttttg atccaaatcg tcaatatcag gatagggaca
    17461 ttgctgctca accacaaaaa cagccacacg ctctttatag atggcaaaca attcatcttt
    17521 tgttaactga tcaaatgctt taacaaccca cattagctag cctccaaaat cactggtaca
    17581 atttccttta tgataacata atagcatata tcagccataa tggaacgaaa aaaacctgac
    17641 tcttaatgga cgatgtcgtg atgataatta catcttgtct caaaagctgg taatcatcac
    17701 aggcacagaa aaatgtgccc cttctgttgc tttttgagaa aaagttcact tgctttttgg
    17761 tagttttttg gtatcatact aaaaaataga cttaattaag gagatacagc ttggaaacaa
    17821 aagatttaaa gaagcttgct aaagctgagc tgcactgcca tttagacggt tctttgtcat
    17881 tagacactat tcgtcagttg gcggctttgg cgcaggtaga tgttcctcaa gatgattctg
    17941 agttaaagca gctggtaacc gcaccggaaa cctgtgaatc cttgatggat tatttaaaaa
    18001 cctttgatgt tatcagacca ttattacaaa cgcctcaggc tttaacattg gctgcttatg
    18061 atgttgtgaa gcaggctgcc cttgaaaatg tcatctacat tgaaattcga tttgctcctg
    18121 agttgtcaat ggatcagggc ttgaccgcca ctcaggtggt agaggcagtt ttaaaaggac
    18181 tcgagcaagg acaaaaagag tttggcattg tcgctaaggc tattgtgtgt ggcatgcgtc
    18241 agtcctcact agacattagc agagagattt ttgcaaatgt cttagagtgg gccaataaag
    18301 gcttggtagg ctttgatttt gcaggcaacg agctggactt tcctccagct gtcttagcag
    18361 atttgatcaa agagacgcag gcctatgggt taccatttac gcttcatgct ggtgagtgtg
    18421 gctgtccaaa ctatattgtt gatgctattg atttaggtat caaacgctta gggcatgtga
    18481 cggccattca taaccaaaag gatttattgg ccaagtttat cgccaatgat gtgacagcag
    18541 agctgtgctt cactagtaat ctacaaacca aggctgctag gactgttgag gactttcctt
    18601 atatgcagct aaggcaggct ggcgctaaat tatccattaa cacagacaat cgaacagtat
    18661 ccgataccaa tctgacaaag gaatatgaac tgtttgtcaa gcactttgag acaagcgtca
    18721 cagacttttt agagcataat cgtgatgcta ttaaggctag ttttgccagt ccggctgaaa
    18781 aagaagcttt attggatcgt ttggaaaagg cttatcagtc ttacatcaag aaataatgct
    18841 tttcttggca aagtatgata aaatatactg acatttagtt attttgggag gaaattatgg
    18901 cattagccaa aatcgtttat gccagcatga caggaaatac tgaagaaatt gctgatattg
    18961 ttgctaataa attgcaagaa ttgggacatg atgttgaggt tgacgagtgt acaacagttg
    19021 atgcttcaga gcttgaggct gctgatatgg caatcgttgc gacctatacc tatggtgatg
    19081 gggacttacc agatgagatt gtcgactttt atgaggactt gcaggatttg gatttgtcag
    19141 gcaagatcta cggtgtcgtg ggctctggtg atacctttta tgattatttc tgcaaatcag
    19201 ttgatgattt tgacgaacag ctcgctgcca ctggtgccac taagggagct gactcggtta
    19261 aggttgattt agctgctgag gaagaggata ttgctcgcct agaatccttt gctgagcaaa
    19321 tgtcacaggc attagaggca taagtaagac ttttgataca gattggtaaa acggtcagtg
    19381 gaggcttgcg ttttttacca ccaaatgcat gaaaaactga tattttctga tcgttttttc
    19441 atgactatgt gctctttttc aagaaaagtc atgccattat tagcctgaat gcaaacaatt
    19501 gatagtgtca aaatgttgat catatagtaa aaaaatgcat gtgactagaa agcagttaca
    19561 tgcattttcg tcatgcgttt gtcgtgaggc attttggggg ttacttgctt actgagctga
    19621 aattcactat aataaaaaga taaataaaga aaagaagaag ttaggtgaat gatgggatta
    19681 gagaccatac gacaagacat taatgctgtt gatcgtcagt tgattgcttt gctggaaaag
    19741 agaatggtct tggctgacca agtagcggcc tataagcagg tacatgatgt gccagtgctt
    19801 gatcaagagc gagaggctga ggtcctaagg agcgtgtcac agcagattcg gcataaggcc
    19861 tttgagcctg ccattcttga gctatttaag acaattatgg cagtatcaag gcgttatcag
    19921 gctgagcaaa tagcggttgg ttcaaatgat gatgaagcct attaaaaaca atcaagacat
    19981 cagtataggt gataatgtct atttggcttt tgcagccctg ctcgttgggg tggtggtagg
    20041 tgtgatagat actgtttttg gacaaggctt gttgctcttg tctgctgttc gtgatgctca
    20101 tctcatttac ctgttaccct gcttagctct tgctggactt gtgattgtgt tcttatatga
    20161 gcaatatggc caaatcgcta agcaggggat gggcttagtt tttgatgtgg ggaatggtga
    20221 aaaaacaaga ctaccactgg tgttgattcc gttgattatc ctctcaacct ggctgacgca
    20281 tttatgtgga ggcagtgctg gtcgtgaagg cgtagcggtt caaattggag cgacaggtca
    20341 catttttttg gacgtcttag acatcttaag gacaagtcac agctgttttt agtcatggga
    20401 atggccgcag gctttgcggg cttatttcaa acgccaatga cagcggttgt ttttgcctta
    20461 gaggtcctgt tgctaggaaa tataagctat ttagccttgc taccttctct tatagcagcc
    20521 tttaccgcct cttggacctc tcattgccta ggcttagaaa aattttcagt cccgatagcc
    20581 aaggccttga aaatcacccc gataaccttt gggaaattag tgctactagg ccttattttt
    20641 ggcttggctg gtaatctttt tgcctccttg ttagcaaggg ctaagccata cattgcagca
    20701 aggctgccaa atccttatta tcgtgtgttg cttgttggtg gttttctatc gcttagcctg
    20761 ctgctgtgcc attacgggcg ctatagtggc ctagggacta acttaattac agcggccttt
    20821 agtcatcagc ctattgctaa ttatgattgg ctattaaagc tcttgtttac cattatcact
    20881 ctctcggctg gctttcaggg cggtgaggtc actccacttt ttgctattgg tgcggcttta
    20941 ggaattgtcc tagcaccatg gcttggcttg ccggctcagt tggctgcagc ccttggctat
    21001 gctgcggtat ttggcagtgc caccaatacc tttttagccc cgatatttgt tggattagag
    21061 gtttttggtg caacaaacgc aactgcttac tttatcgtga tagcctttgc ttatatggtg
    21121 agccgaaggc attcaatcta cactaagcaa agggtgacca ctagcatcgc ttcctagtgt
    21181 cttggtcagt tttttggaga aaatagcttt acaagtgggg cttattttgt tacaataggc
    21241 tccgtgtgta atggacgcac aaaaattacg gctaatccgc taagactcgc gcttaagatt
    21301 agtaagataa ggagaataaa caatgaatcc attaattcaa agcttgacag agggtcaact
    21361 tcgtactgat attcctagct tccgtcctgg tgacactgtt cgtgtgcacg caaaggttgt
    21421 cgaaggatct cgtgaacgta tccagatctt tgagggagta gtcatttcac gtaaaagtca
    21481 aggtatctca gagatgtata ctgttcgtaa gatttctagt ggtatcggtg tagagcgtac
    21541 cttcccaatt cacacaccac gtgttgaaaa gattgaggtt gtgcgtcatg gtaaggttcg
    21601 tcgtgctaag ctttactacc tacgtgcctt gcaaggtaag gcagcgcgta tcaaggaaat
    21661 tcgtcgctaa aaagagcata cgagaggttt ttcactgtct tatgaaagga ctgctggagc
    21721 agcagggtct ttgggacaag ctttttttcg caggtatgtg aacctacgct caattcaaga
    21781 catatcaaag gctcattcta tgatagagtg ggctttttga ttgtgatcat gctttagtgc
    21841 ctaaataaat gacagcagcc tgactaatga aaggcttact tgactttgga aatgctcaag
    21901 gcttgcgcta ccagatagaa gctgacatca tgccatagca gtcaagggga agaaggacta
    21961 gattttttgg cgaggtgttg atctgtgacc ctgatgttgt tgggaatatg agagtaattt
    22021 aaaatttcgt cttgcattct acctttttct aggttacaat agacaagtaa cctgattagt
    22081 gaagctaaaa gacgtagcga tgggttctaa aaaagaatga ttctggcgtt tttggctaac
    22141 ctaagctgat agctttgcta ggcagtgtct tagtcatctg gtcagtcctg ctagtttaac
    22201 ggataaaaca agcgcctcct aagcgctagc tgtgggttcg attcccgcgc gggacattaa
    22261 aaacaaagta aaaagagtct gagaaggttt gagctgcccc taattgttag atttttttct
    22321 aactcttgaa gtgtgggtca aagactattt gtctcaggac tctttttaat tggtttttac
    22381 taagctgctt catctagttc ttcagttgct aagttgtttc cttcttctgt atgttggttt
    22441 tcatcaagta gcattcctgt gcggtaatct aatgctgcca aaggtgatac attatccaga
    22501 acaactgagg ttataccata atgatcaacg gattctttgt tgcctcccaa tttgatttgg
    22561 aggagctctc cgttttgatc aattccaacg tactgtaaca ctacttgacg aggaactaat
    22621 tcatcattct gataaatagg agttacctta taatctagcc aaaagttagg gtgtatggct
    22681 aaccaattgt ctagtctatt ttcataataa agcattccta aaggattttt atcactaaaa
    22741 cctgtattaa ggtattttgt catagtaact aaatttttgg gttcatcatt taggccgcta
    22801 aactgataac cgactagatg tccgcgatcc attaaccaag tctttttccc tctagaatta
    22861 atgacttgat agttatgcca gccgggagga ttaaatctaa gcgcttttct tttgagagtt
    22921 ggttcatctt gatctttgag ttgtatgtgt gcataggtgg ctctttgtaa atgatcaaga
    22981 tctcccagag ctatttggta ttttccagta aacggtaaaa ttcctggtat ttcggtagct
    23041 tttgttccca atgatatttc cgttgtatct gggaaggttc taagttttct tgcagattga
    23101 acagagttag ctgtgaaaat agtcagaata gttaacaaaa caattgttag acttttccag
    23161 ttacggcgac gtgatttaga catatcaatg ccctcctttt tttgtttacg agttaagtat
    23221 a
//
LOCUS       DARYXZ010000035        23205 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYXZ010000035 DARYXZ010000000
VERSION     DARYXZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23205
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..376)
                     /locus_tag="TV186_001293"
     CDS             complement(<1..376)
                     /locus_tag="TV186_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000600261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1532685.1"
                     /translation="MILGETYRKMREEKGISISSLAGYEISKSQISRFELGETEISIF
                     KLLYLLEKLGITFEEFLLACNNYEPSEFNTLIKAVQNSAYNNKVETLISMIEQENKLF
                     EETNSHYHKLNSIFIQSIISGLD"
     gene            1012..2496
                     /locus_tag="TV186_001294"
     CDS             1012..2496
                     /locus_tag="TV186_001294"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL1532686.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            2536..3837
                     /locus_tag="TV186_001295"
     CDS             2536..3837
                     /locus_tag="TV186_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1532687.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            4217..4525
                     /gene="rpsJ"
                     /locus_tag="TV186_001296"
     CDS             4217..4525
                     /gene="rpsJ"
                     /locus_tag="TV186_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL1532688.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHNYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            4823..5449
                     /gene="rplC"
                     /locus_tag="TV186_001297"
     CDS             4823..5449
                     /gene="rplC"
                     /locus_tag="TV186_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL1532689.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            5474..6097
                     /gene="rplD"
                     /locus_tag="TV186_001298"
     CDS             5474..6097
                     /gene="rplD"
                     /locus_tag="TV186_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL1532690.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            6097..6393
                     /locus_tag="TV186_001299"
     CDS             6097..6393
                     /locus_tag="TV186_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL1532691.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            6411..7244
                     /gene="rplB"
                     /locus_tag="TV186_001300"
     CDS             6411..7244
                     /gene="rplB"
                     /locus_tag="TV186_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL1532692.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            7356..7634
                     /gene="rpsS"
                     /locus_tag="TV186_001301"
     CDS             7356..7634
                     /gene="rpsS"
                     /locus_tag="TV186_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL1532693.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7650..7994
                     /gene="rplV"
                     /locus_tag="TV186_001302"
     CDS             7650..7994
                     /gene="rplV"
                     /locus_tag="TV186_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL1532694.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            8007..8660
                     /gene="rpsC"
                     /locus_tag="TV186_001303"
     CDS             8007..8660
                     /gene="rpsC"
                     /locus_tag="TV186_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL1532695.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8664..9077
                     /gene="rplP"
                     /locus_tag="TV186_001304"
     CDS             8664..9077
                     /gene="rplP"
                     /locus_tag="TV186_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL1532696.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            9087..9293
                     /locus_tag="TV186_001305"
     CDS             9087..9293
                     /locus_tag="TV186_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL1532697.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            9318..9581
                     /gene="rpsQ"
                     /locus_tag="TV186_001306"
     CDS             9318..9581
                     /gene="rpsQ"
                     /locus_tag="TV186_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL1532698.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9606..9974
                     /gene="rplN"
                     /locus_tag="TV186_001307"
     CDS             9606..9974
                     /gene="rplN"
                     /locus_tag="TV186_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL1532699.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            10058..10363
                     /gene="rplX"
                     /locus_tag="TV186_001308"
     CDS             10058..10363
                     /gene="rplX"
                     /locus_tag="TV186_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL1532700.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            10387..10929
                     /gene="rplE"
                     /locus_tag="TV186_001309"
     CDS             10387..10929
                     /gene="rplE"
                     /locus_tag="TV186_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL1532701.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            10945..11130
                     /locus_tag="TV186_001310"
     CDS             10945..11130
                     /locus_tag="TV186_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL1532702.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            11463..11861
                     /gene="rpsH"
                     /locus_tag="TV186_001311"
     CDS             11463..11861
                     /gene="rpsH"
                     /locus_tag="TV186_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL1532703.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            12183..12719
                     /gene="rplF"
                     /locus_tag="TV186_001312"
     CDS             12183..12719
                     /gene="rplF"
                     /locus_tag="TV186_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL1532704.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            12822..13178
                     /gene="rplR"
                     /locus_tag="TV186_001313"
     CDS             12822..13178
                     /gene="rplR"
                     /locus_tag="TV186_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL1532705.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            13197..13691
                     /gene="rpsE"
                     /locus_tag="TV186_001314"
     CDS             13197..13691
                     /gene="rpsE"
                     /locus_tag="TV186_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL1532706.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13706..13888
                     /gene="rpmD"
                     /locus_tag="TV186_001315"
     CDS             13706..13888
                     /gene="rpmD"
                     /locus_tag="TV186_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL1532707.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            14090..14530
                     /gene="rplO"
                     /locus_tag="TV186_001316"
     CDS             14090..14530
                     /gene="rplO"
                     /locus_tag="TV186_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL1532708.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            14547..15851
                     /gene="secY"
                     /locus_tag="TV186_001317"
     CDS             14547..15851
                     /gene="secY"
                     /locus_tag="TV186_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL1532709.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            16003..16644
                     /locus_tag="TV186_001318"
     CDS             16003..16644
                     /locus_tag="TV186_001318"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL1532710.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16762..16980
                     /gene="infA"
                     /locus_tag="TV186_001319"
     CDS             16762..16980
                     /gene="infA"
                     /locus_tag="TV186_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL1532711.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            17006..17122
                     /gene="rpmJ"
                     /locus_tag="TV186_001320"
     CDS             17006..17122
                     /gene="rpmJ"
                     /locus_tag="TV186_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL1532712.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            17140..17505
                     /gene="rpsM"
                     /locus_tag="TV186_001321"
     CDS             17140..17505
                     /gene="rpsM"
                     /locus_tag="TV186_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL1532713.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            17523..17906
                     /gene="rpsK"
                     /locus_tag="TV186_001322"
     CDS             17523..17906
                     /gene="rpsK"
                     /locus_tag="TV186_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL1532714.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            17953..18891
                     /locus_tag="TV186_001323"
     CDS             17953..18891
                     /locus_tag="TV186_001323"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL1532715.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            18906..19292
                     /gene="rplQ"
                     /locus_tag="TV186_001324"
     CDS             18906..19292
                     /gene="rplQ"
                     /locus_tag="TV186_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL1532716.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(19510..19741)
                     /locus_tag="TV186_001325"
                     /pseudo
     CDS             complement(19510..19741)
                     /locus_tag="TV186_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20597..21847
                     /locus_tag="TV186_001326"
     CDS             20597..21847
                     /locus_tag="TV186_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532717.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            21837..22712
                     /locus_tag="TV186_001327"
                     /pseudo
     CDS             21837..22712
                     /locus_tag="TV186_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22733..23026
                     /locus_tag="TV186_001328"
     CDS             22733..23026
                     /locus_tag="TV186_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1532718.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT         7161 a         4137 c         5109 g         6798 t
ORIGIN      
        1 tatcaagtcc agaaatgata ctttggataa aaattgaatt taatttatga taatgagagt
       61 ttgtctcttc aaacaattta ttttcttgtt ctatcatact tattagtgtt tcgactttat
      121 tattgtatgc agaattttga acagctttta ttagtgtatt aaattcagat ggttcataat
      181 tgttacaggc gagcaagaat tcttcaaagg ttattccgag tttttctagt aaatataata
      241 acttgaaaat agaaatttcc gtctctccta attcaaatct tgaaatttga gattttgaaa
      301 tttcatatcc tgctaatgaa gaaatagaaa ttcctttttc ttcccgcatt tttctatagg
      361 tttcacctaa gatcatagat tatctccgtt tgtagttaaa aagtggaaag cgtgacaaat
      421 gatgagaaaa agttacaagt tacttaaatt gattcttgat attatcatta ttataggttt
      481 atgtcaataa tttttgtaga ttgcatgaag tataatgcct ataagttttt agtactcaat
      541 tttatgattt aatatttaaa ttaagcaata gtcaagtcac ctttcactaa gaaaaatcac
      601 ttgattattg cttagttttt tctaatggag gatttttagt ttagaagctt tgagtttaga
      661 cctcaaaact tagatatgga attcgaaagg cagtcactgc tgtcaacatt actttgggaa
      721 agttcctata agagactttt cattagactg aagtagcttc aatagctcta aaactaccta
      781 gactcaagta acaacaagtc cttagaattg attttctaag ggcttttttg ctgcctcaag
      841 gtaaagacat gttcagcaac aaattgactg gctagaccag tcctttattt atgctgatgg
      901 cttgagactg ctgggttatt agcacagaaa atggctgtct ccaaatccta gaaggcttat
      961 gattggaata tgatataata gtcaaaagaa atgatgaggt gatgtgaagc aatgccaatg
     1021 atgtaccaat caacaagaaa tgcagctaat aaggtaacag ctagtcaagc gattttaagt
     1081 ggcctagcag atgatggtgg cttgtttact cctacaagca tgccagtgct ggatctagat
     1141 tttgaggagc taaagaccaa gtcctatcaa gaggttgcca agcttatttt atcagccttt
     1201 tttgatgact atactgaagc agaattagat gcttgtatct cttctgccta tgatgataag
     1261 tttgatacag cagtgatagc acctctagct acgttaaagg attatcataa tttggagcta
     1321 tttcatggct caaccatcgc atttaaggac atggctctat ctattttgcc ttatctcttg
     1381 acaactgctg ctaaaaagca aggtgtggag cgaaaaattg cgattttaac cgctacctca
     1441 ggtgatactg gtaaggcagc aatggcaggc tttgttgatg ttccgggaac ggatattatt
     1501 gtcttttatc ctaagtcagg cgttagcagg attcaggagc tgcagatgat cacacaggcc
     1561 ggtcacaata cccatgttgt ggcgattgaa ggcaattttg atgatgctca aacagaggtc
     1621 aagcgcctgt ttaatgaccc tgatttgcgt gagcggctag cagctcaaca gatacagctg
     1681 tcttcggcca attcgatgaa tattggtcgt ttgattcctc aggttgtcta ttatatttat
     1741 gcttatgccc agttggtaag gcatcagcga cttgaagctg gagagacgat taacatagta
     1801 gtgccgacag gaaattttgg caatctactg gttgcctact acgccaaaga aattggactt
     1861 cctgttgcca aattcatctg tgcttccaat gaaaacaatg tcttgacaga tttctttgct
     1921 agtggtaggt atgataaaaa gcgtcccttc aaggtgacta ctagtccatc aatggatatt
     1981 ttggtgtctt caaatttaga gcgcttggtt ttttatttac taggcaatga tgcccaaaag
     2041 acagcagtat taatgaagag cttggcagaa acaggtcagt atcagctagc tgatgcagat
     2101 cagtctatcc ttgatttatt tgcggcaggc tttgcaacag agcaagagac tgctaaagag
     2161 atcaaaacga tatttgagtc tgatcattat gtgcttgacc cacatacagc tgtagcttca
     2221 gctgtttatc gtgcttatcg ggagcaatca ggtgactcta gaccgactat tgttgcgtca
     2281 actgctagtc cttataagtt tccgcgggta gttgtggaag ctattagtgg tcagcaggtt
     2341 gccagtgatt ttgaggcgct tgagcagttg gctgatatat caggtgtagt cgtgccacaa
     2401 gcggtcaatg gcttacagga ggcgcccatt cgtcatagcc ttttagtgac agtagcagat
     2461 atgcagcagg cagtagaggc ttatcttgga gtataggagg cataaaggag ctccctttca
     2521 attgatatga atataatgac tcacaataga aaaaagatac tgtccttggc ccttccatca
     2581 atggcagaaa atatattgca aatgctgatg ggaatgatag acaattattt ggctgctcaa
     2641 attggactta cggctgtttc aggcattgcg attgctaata atattctgac gatttatcag
     2701 gcccttttta tcgcattagg tgctgcagtc tccagtctca ttgctagaag cgtaggagag
     2761 caaaaccatt ctaaagaaat cgactacatg gcaaatgcta tcttagtaac gggggctcta
     2821 tcagttcttc taggcttgat gtccgtagtg ggacataaaa gcatattagc ctttctggga
     2881 gcagctagtc tggtagctag acttggtggg cagtatttag ccattgtcgg tggaatgatt
     2941 cttagtcttg gtcttttcac gagcttaggt gcgattattc gtgctaaggg ccagcctagc
     3001 attcccatga aggtcagcct tttaactaat ttgctaaacg ctgtattttc agccctttct
     3061 ctttacatat ggggatttgg agtgataggg attgcttggt caactgttgc atcacgtctc
     3121 attggagttg ttattctatg tcactttctt cctattaaag aaattattaa acgttttgct
     3181 aatcccttag ataaagagat ctttagcctc tctcttccag cggctggtga gcggctcatg
     3241 atgcgagctg gtgatgtgct gattgttact attattgtta gatttggaac agaggccttg
     3301 gcaggcaatg cgattggaga aaccttaact caatttaatt atatgccggg acttgctatg
     3361 tcaactgcga cagtcatttt agttgccaat cagttgggca gtggcaaagg ggctacaata
     3421 gcgaaaactg taaaagaaac ctttttgtta gccaccctga tgatgcttgt tatgggcttg
     3481 atcacttatt tgctaggccc taatctactg cccttattta cagcagatgc caaggctcag
     3541 caggctggta tggttgtctt agtcttttct cttttggggg taccagcaac agccgggacc
     3601 ttggtttata cagcagcctg gcagggtatc ggacaagcta agcttccctt ttatgcaaca
     3661 acgattggta tgtggctggt tcggatttct ttgggctact ttattggagt aaccttaaat
     3721 tatggagtaa taggtgtttg gcttgcgact attttggaca atgctaccag atggctcatt
     3781 cttgcagtgg cttttaagaa gcagcaaagg cagctttttt cggactgtca tagctaaact
     3841 ttgtatttag gtctcaagac ttctgagtgg tgactttcct tttgggagtc agccactgtc
     3901 atcagaatgt aaagtacgcc tgaggctctg tttgctaata gcttctctta tctgcggaag
     3961 atcaaagagg attgctggaa cagctgaggt ttgtcttcaa tctggcttgc cctttcttag
     4021 ggcaagtttt tttgaaaaaa tcccctgaaa ggcttgcaat gccttattaa ttctgctatt
     4081 atattatggt gctgtaaaaa tacagcttta gctgtgatac gagaggttgc gacacgctcg
     4141 gttgcattgc cacgtgacag gtgtcggttt tctcgaggag ctagcctatt atcgtaaata
     4201 gacgagagga gaaaagatgg caaacaaaaa aatccgtatc cgcttgaaag cgtacgaaca
     4261 ccgtacactt gatacagcgg cagaaaaaat cgttgaaact gcaactcgta caggtgcaac
     4321 agtagctgga ccagttccac ttccaactga acgtagtctt tacaccatta ttcgtgcgac
     4381 tcacaattat aaagattctc gcgaacaatt tgaaatgcgt acacacaaac gtcttattga
     4441 tattgtgaac ccaacgcaaa agactgttga tgcacttatg aaattggacc ttccaagtgg
     4501 tgtcaacgta gaaatcaagc tttaattgtt tgaaacatga gtgaggaacg agttcatatc
     4561 taattgaaca caggctaaac tctgtgtgaa aaagagacac agccgttcta attttaatta
     4621 gattacggat gtggctacct gtaggtgtaa atcttcctag aaacagaagt ttcttcgtca
     4681 gatttcctat tttcactgtg agtttgacgc cttaagtatc ttgctttgag cataaaaaac
     4741 gctcgtaaaa aacttttttg agcataaaaa acgctcacta aaaacttttt gaaatattat
     4801 taagaaaagg aattattttc tcatgacaaa aggaatctta ggggaaaaag tgggaatgac
     4861 tcaaatcttc actgaatccg gtgaatttat ccctgttact gtcatcgaag caactccaaa
     4921 cgttgtgctt caagttaaga ctgttgaaac agacggttac gaagcaattc aagttggttt
     4981 tgatgataaa cgtgaagtat tgagcaacaa acctgccaaa ggccatgtag caaaagctaa
     5041 cacagctcct aagcgcttca ttcgtgaatt caaaaacatt gaaggcttag aagtaggtgc
     5101 agaaatcact gtggatatct tcgcagctgg ggatgttgtt gatgtaactg gtacttcaaa
     5161 aggtaaaggc ttccaaggtg ttatcaaacg ccatggtcaa tcacgtggtc cgatggccca
     5221 tggttctcgt taccatcgtc gtccaggttc tatgggacct gtttcaccaa accgcgtttt
     5281 caaaaacaaa catttggcag gacgcatggg tggcaatcgt gtaactattc aaaatcttga
     5341 aattgtacaa gttatcccag aaaagaacgt tattcttatt aaaggtaacg taccaggtgc
     5401 taagaaatct cttatcacca tcaaatcagc agttaaagct gctaaataat aagaaaggag
     5461 aaaacagtta aaaatggcaa acgtaaaact atttgaccaa actggtaaag aagttagcac
     5521 agttgaatta aatgatgata tctttggtat cgaaccaaac gaatcagttg tttttgatgt
     5581 tgtaatcagc caacgtgcta gccttcgcca aggtactcat gcggttaaaa accgttcagc
     5641 agtatcaggt ggtggacgta aaccttggcg tcaaaaagga actggacgtg ctcgtcaagg
     5701 ttctatccgc tcaccacaat ggcgtggtgg tggtgttgtc tttggaccaa ctccacgttc
     5761 atatggatac aaacttccac aaaaagttcg tcgccttgct ttgaaatcag tttactcagc
     5821 aaaagttgct gaagataaat ttgtagctgt agaaagcctt tcatttgcag caccaaaaac
     5881 agctgaattt gcaaaggtgc tttcagctct tagcattgat acaaaagtac ttgttcttgt
     5941 tgaagaagga aatgaatttg cagcactttc tgcacgtaac cttccaaacg tagctgtggc
     6001 aacagcagcg actgcaagtg ttcttgatat cgtaaacgca gacaaacttc ttgtaacgaa
     6061 agaagcaatc tctacaattg aggaggttct tgcataatga atttgtacga cgtaatcaaa
     6121 aaaccagtta ttactgaaaa atcaatgtat gcccttgaag aaggtaaata cacatttgaa
     6181 gttgacacac gtgcgcacaa actgttaatc aagcaagctg ttgaagctgc atttgacgga
     6241 gttaaggttg caagcgtcaa tactgttaac gttaaaccaa aggctaagcg tgttggtcgt
     6301 tacacaggtt ttacttcaaa aactaaaaag gctatcatca ctcttacagc tgattctaaa
     6361 gcaatcgagt tgttcgcagt tgaagctgaa taatctaagg aggaaataac gtgggtatta
     6421 aagtttataa accaacgaca aatggccgtc gtaacatgac ttctttggat ttcgctgaaa
     6481 tcacaacaag cacacctgag aaatcattgc ttgtttctct taaaaacaaa gctggtcgta
     6541 acaacaatgg tcgcattaca gttcgtcacc aaggtggtgg acacaaacgc cattaccgtt
     6601 tgattgactt caagcgtaac aaagatggtg ttgaagcagt tgttaaaaca atcgaatacg
     6661 atccaaaccg tactgcaaac attgcacttg tacattacac tgacggagtt aaggcttaca
     6721 tcatcgctcc taagggtctt gaagtaggtc aacgtattgt ttctggacca gatgcagata
     6781 ttaaggttgg taatgcactt ccattagtaa acattcctgt tggtacagtt gttcacaaca
     6841 ttgagcttaa gcctggtaag ggtggagagc ttgtacgtgc tgctggagct tctgctcaag
     6901 tacttggtca agaaggcaaa tacgttcttg ttcgtcttca atcaggtgaa gttcgtatga
     6961 ttcttggaac atgtcgtgca actgttggta cagttggtaa cgagcaacaa tcacttgtta
     7021 acattggtaa agcaggacgt agccgttgga aaggtatccg cccaacagtt cgtggttctg
     7081 taatgaaccc taacgatcac ccacatggtg gtggtgaagg taaagcacca gttggacgta
     7141 aagcgccatc tactccttgg ggtaaaccag cgcttggtct taaaacacgt aacaaaaaag
     7201 ctaaatctaa caagcttctt gttcgtcgtc gtaacgaaaa ataagcggca aatctagcat
     7261 aagcttattc aatcattccg ccagctcggt agagtttgag cttgctctca tgctcaagcc
     7321 gctgtggtac attatttaaa ggagaaaact acaaaatggg acgtagtctt aaaaaaggac
     7381 ctttcgtcga tgagcatttg atgaaaaaag ttgaagctca agctaatgac gaaaagaaaa
     7441 aagtaatcaa aacttggtca cgtcgttcaa cgattttccc aagtttcatc ggatatacaa
     7501 tcgcagttta tgatggccgc aagcatgtac ctgtgtacat tcaagaagac atggtaggtc
     7561 acaagcttgg tgaatttgca ccaactcgta cctacaaggg tcacgcagct gacgacaaga
     7621 aaacacgtcg ttaataggag gaggacacaa tggcagaaat tacttcagct aaagcaatgg
     7681 ctcgtacagt gcgtgtttca cctcgtaaaa cacgtttagt acttgatctt atccgcggta
     7741 agaaagttgc tgatgcaatc gcaatcttaa aattcactcc aaacaaagca gctcgtgtta
     7801 ttgagaaaac tcttaactca gcaattgcta acgcagaaaa taactttggt ttggaaaaag
     7861 ctaacttggt agtatctgaa acatttgcaa acgaaggacc aacaatgaaa cgtttccgtc
     7921 cacgtgcaaa gggctcagcg tcaccaatca acaagcgaac aactcacgtt acagtagttg
     7981 tatcagaaaa ataaggaggt aaaatcgtgg gtcaaaaagt acatccaatt ggtatgcgtg
     8041 tcggaatcat tcgtgactgg gatgcaaaat ggtatgctga aaaagaatac gcggattacc
     8101 ttcatgaaga tcttgcaatc cgtaaattca ttaacaaaga attggcagag gcttcagttt
     8161 caacaattga aattgagcgt gctgtaaata aagttattgt ttcacttcac actgcaaagc
     8221 ctggtatggt tatcggtaaa ggtggagcaa atgttgacgc tcttcgcgct cagcttaaca
     8281 aattaactgg aaaacaagta cacatcaaca tcatcgaaat caaacagcct gatcttgatg
     8341 cccaccttgt tggtgaaaac attgctcgtc agcttgagca acgtgttgct ttccgtcgtg
     8401 ctcaaaaaca agctattcaa cgtacaatgc gtgctggagc taagggaatc aaaactcaag
     8461 tttcaggtcg cttgaacggt gcagatatcg cgcgtagcga aggctactca gaaggaactg
     8521 ttcctcttca cacacttcgt gcagatattg actatgcttg ggaagaagca gatactacat
     8581 acggtaaact tggtgttaaa gtttggattt atcgtggtga agttcttcca gctcgcaaaa
     8641 acactaaagg aggcaaataa cagatgttag tacctaaacg tgttaaacac cgtcgtgagt
     8701 ttcgtggaaa aatgcgcggt gaagcaaaag gtggaaaaga agtatcattc ggtgaatatg
     8761 gtcttcaagc tactactagc tcatggatca ctaaccgcca aatcgaagct gctcgtatcg
     8821 ctatgactcg ttacatgaag cgtggtggta aagtttggat taaaatcttc cctcacaaat
     8881 cttatacagc taaagctatc ggggttcgta tgggttctgg taagggtgca cctgaaggtt
     8941 gggtagcacc agttaagcgt ggcaaggtta tgtttgaggt tgctggtgtt tctgaagaaa
     9001 tcgctcgtga agcacttcgt cttgctagcc acaagctacc agttaaatgt aaattcgtaa
     9061 aacgtgaagc agaataagga gaagacatga aacttgaaga aatcaaaaag tttgttgctg
     9121 agcttcgtgg cttgtctcaa gaagagcttg ctaagaaaga aaacgaactc aaaaaagaac
     9181 ttttcgacct tcgttttcaa gctgcagcag gtcaactaga tcaaactgct cgtttgaacg
     9241 aagttaaaaa acaaattgca cgtgtaaaga ctgtgcaatc tgaaatgaaa taatagattg
     9301 ggaaaggagt attctaaata atggaacgta atcaacgtaa aacccttgtt ggacgtgttg
     9361 tatctgacaa gatggacaaa acaatcactg ttatagttga aacaaagcgt aaccacccag
     9421 tctatggtaa acgtatcaac tattctaaaa aatacaaagc acatgacgaa aagaaccttg
     9481 ctaaagaagg cgatatcgtt cgtatcatgg aaactcgtcc actttcagct acaaaacgct
     9541 tccgtcttgt agaaatcgtg gaagaagctg ttattatcta atcaaactaa aaggagacaa
     9601 ttgaaatgat tcaacaagaa actcgcttga aagttgctga taatagcggt gctcgtgaga
     9661 tcttgactat caaggttctt ggtggttcag ggcgtaagtt tgctaacatc ggtgacgtca
     9721 tcgttgcatc tgtaaaacaa gctactcctg gtggagcagt taaaaagggt gatgttgtta
     9781 aggctgttat tgttcgtaca aagagtggtg ctcgtcgtcc agacggttca tacatcaaat
     9841 ttgatgacaa tgcggctgtc attattcgtg atgacaagac tcctcgtggg actcgtatct
     9901 ttgggcctgt tgcacgtgaa ttgcgtgagg gtggctacat gaagatcgta tcacttgcac
     9961 cagaagtact ttaattttaa tcattaaaca aactaagtcc cctaggctag cctagggtgc
    10021 ccataggggc gtaagaaaat aataggagaa acccataatg tttgtaaaaa aaggcgacaa
    10081 ggttcgcgtt attgctggta aggacaaagg tgttgaagct gttgttctta aagcacttcc
    10141 aaaagtaaac aaagttattg ttgaaggcgt agccatcatc aaaaagcatc aaaaaccaaa
    10201 cagcgaaaat cctcaaggtg ctatcgttga aaaagaagca ccaatccatg catcaaacgt
    10261 tcaagttctt gataaaaatg gtgttgctgg acgcgttggt tacaagtttg tagacggcaa
    10321 aaaagttcgt tacaacaaaa aatcaggcga agtgcttgat taatcacgaa ggaaaggaga
    10381 agcataatgg caaatcgttt aaaagaaaaa tatactaacg aagtaattcc tgcgttgaca
    10441 gagaagttta attacacatc agttatggct gtgccaaagg ttgagaaaat cgttcttaac
    10501 atgggtgtgg gtgacgctgt atcaaacgct aaaaaccttg aaaaagctgc tgcagaattg
    10561 gcgcttatct caggtcaaaa accacttatt actaaagcta agaaatcaat cgctggcttc
    10621 cgtcttcgtg aaggtgttgc tatcggtgcg aaggtgacac ttcgtggcga acgcatgtac
    10681 gaattcctag acaagctagt tagcgtttca cttcctcgtg ttcgtgactt ccatggtgtt
    10741 ccaacaaaat catttgatgg tcgtggtaac tacactcttg gtgtgaaaga acagcttatc
    10801 ttcccagaaa tcaactttga tgatgttgat aaagtgcgtg gtcttgatat tgttatcgta
    10861 acaactgcta acactgacga agaatcacgt gaattgctta aaggtcttgg aatgcctttt
    10921 gcaaaataat agggggtaac taaattggct aaaaaatcta tgattgctaa aaacaaacgt
    10981 cctgcgaagt attctacaca agcttacact cgttgtgaaa aatgtggacg tccacattct
    11041 gtttaccgca agtttaagct ttgccgcgtt tgcttccgcg agttggctta caaaggccaa
    11101 atcccaggtg ttgttaaagc gtcttggtaa aatgatgatg tgagagcgtt aagctaccta
    11161 agcaaaaata ggaaaattga cgaagagtct aaatactcta ggaaattttg cacctaaagg
    11221 tagtagcttg aactcagttc aaatgaacaa ataatactat cagatattat gtctgattcg
    11281 atgcaaaggc aaagtgtcaa tttgaacacg ggcgaaagcc ggtgtcaaaa agataaacat
    11341 tccttggagg ttttccctcc tgcggaagtt tcctattttg actttggctt ttagcgccct
    11401 ttgtatcatc gattaactag caagtgcagc ttgcaaacta ctagtaagag gagaataata
    11461 aaatggttat gactgaccca attgcagact ttttgacacg tattcgtaat gctaatcaag
    11521 taaagcatga agtgttagaa gtacctgcat caaatattaa aaaagggatt gcagaaatcc
    11581 ttaagcgtga aggctttatc aaaaacgttg aagttattga agatggcaaa caaggaatta
    11641 ttcgcgtatt tcttaagtac ggtcaaaatg gtgaacgtgt catcactaac ttaaaacgtg
    11701 tttcaaaacc aggtcttcgt atttattcta agcgtgagga tgttccaaag gttcttaatg
    11761 gactaggaat tgcaattatt tcaacttcag aaggtctttt gactgataaa gaagctcgtc
    11821 aaaagaacgt tggtggagaa gttatcgcat acgtttggta atttaagaga caaaagccgt
    11881 aacgaacaat ctaaaattag aaaattattg tggcttgctt gcaaacaaaa tagtttgtct
    11941 attttagatg gcagttcgtc ggctgtgctc aaatgatgaa cactatcaac atagcaaacg
    12001 taaaagaact aattgaacat gggctaaagt ctgtgtgaaa aagataaatt tttctagaaa
    12061 ccttggtttc atagtaatgt ttcctatttt cactttgcct tttacgccct aagtatctta
    12121 gttcaccccg tgaaaactcg tcgcgtaagc ggcctgataa tttaacagga gaaaaaatta
    12181 atatgtcacg tattggtaat aaggttatta ttatccctgc aggcgttgaa atcattaaca
    12241 acgacaatgt tgttactgta aaggggccta aaggagagct cactcgtgag tttaacaaaa
    12301 atattgaaat caaagtcgaa ggaaacgaaa tgactcttgt acgtcctgac gactcaaaag
    12361 aaatgaaaac aattcatggt acaactcgtg caaacttgaa taacatggtt gttggagttt
    12421 cagaaggttt caaaaaagag cttgaaatga agggtgtcgg atatcgtgca cagcttcaag
    12481 gctctaagct tgttctttca gtaggtaaat ctcaccaaga tgaggtggaa gctccagaag
    12541 ggattacatt tactgtagct aatccaacat caatttcagt tgagggtatc aacaaagaag
    12601 ttgttggtca aactgccgct tacattcgta gcctacgttc accagagcct tacaaaggta
    12661 aaggtattcg ttacgttggt gagtatgtac gccttaaaga aggtaaaaca ggtaaataat
    12721 gttcttagtg gaatatggca taggcttgct tatgtcatgc tctacaagct caattgataa
    12781 tttgtcggaa agacaaactt aaatattaag aggtgaaaat tgtgatttcg aaaccagata
    12841 aaaacaaaat ccgccaaaaa cgccatcgtc gcgttcgcgg taaactctct ggaactgctg
    12901 atcgcccacg tttgaacgta ttccgttcta atacaggcat ctacgctcaa gttattgatg
    12961 acgtagcggg tgtaacgctc gcaagtgcat caactcttga taaagaagtt tctaaaggaa
    13021 caaaaactga acaagctgtt gtagtcggca aacttgttgc tgaacgtgcg gtggctaaag
    13081 gtatttctga agtggtgttt gaccgcggtg gatatctcta tcatggacgt gttaaagctt
    13141 tggctgatgc agctcgtgaa aacggattga aattctaata gggaggacac aaaataatgg
    13201 catttaaaga taatgcagtt gaacttgaag aacgcgttgt tgctattaac cgcgttacaa
    13261 aagttgttaa aggtggacgt cgtcttcgtt ttgcagctct tgtagttgtt ggtgatggaa
    13321 acggacatgt tggattcggt actggtaaag ctcaggaagt accagaagct attcgcaagg
    13381 cagttgaagc tgctaaaaag agcatgattg aagtgccaat ggttggcaca acaattcctc
    13441 acgaggttta cactaacttt ggtggagcta aagtattgtt gaagccagct gtagaaggtt
    13501 ctggagttgc tgctggtggt gcggtacgtg ccgtcatcga attagcaggt attgctgata
    13561 ttacttcaaa atctcttggt tcaaacactc caatcaacat cgttcgtgca actgttgaag
    13621 gattaaaaca gcttaaacgt gcagaagaag ttgccgcact tcgtggcatc tcagtttctg
    13681 acttagctta agaaagggga tcatcatggc tcaaattaaa attactttga ctaagtctcc
    13741 aatcggacgt aagccagaac aacgtaaaac ggttgttgcc cttggacttg gtaaattaaa
    13801 ctcttcagtt atcaaggaag ataatgctgc tattcgtggt atggtgacag caatttctca
    13861 cttggtgaca gttgaagatg tcaaataaag agttagctag aaatctctga tttcttgcat
    13921 tagcatgcag aaccggcttt tgtgagttat tcctttgaat gacaagcagt ggtcggttgg
    13981 tgcatatagc atcaggctat gacatagctt gatcatgtat aggcgagttt ctatggagag
    14041 tcctttccct tcatagaggc gctagcattt tacaaaaaaa ggagaaaaaa tgaaacttca
    14101 tgaattgaag cctgccaaag gctctcgtaa agtccgcaat cgtgttggac gcggtacttc
    14161 atcaggcaat ggtaaaacat ctggacgcgg tcaaaaaggt caaaaggctc gtagtggtgg
    14221 tggcgtacgt ctaggctttg aaggtggaca aacacccttg ttccgtcgta ttccaaagcg
    14281 tggatttaca aatatcaaca ctaaagagta tgctcttgtt aaccttgatc aattaaacgc
    14341 ttttgaagat ggcacagaag taactccagt tgttcttaag gaagctggaa tcgttcgtgc
    14401 tgaaaagtca ggcgttaaaa ttcttggtaa cggcgaattg actaaaaaat tgactgttaa
    14461 agcagcgaaa ttttcaaaat ctgctgaagc agccattact gctaagggtg gttcaataga
    14521 agtcatctaa tgaggggata ctcattatgt tcttaaaaat actcaaagac gcattgaaga
    14581 taaagaatgt tagaaataaa atatttttta caatctttat tatccttata ttccgtattg
    14641 gaacacatat cactgttcct ggtgtaaatg caaaaagctt agagcagctg agtgagcttc
    14701 ccttcctaaa tatgttgaac ttggtcagcg gtaatgcaat gagaaacttt tcagttttct
    14761 caatgggtgt tagtccctat attacagcct caatcgttgt tcagctattg cagatggata
    14821 ttttgccgaa gtttgttgag tggggaaaac aaggtgaggt tggccgtcgt aagctaaacc
    14881 aagcgacgcg ctatatttcc cttgtcttag cctttgctca atctatcggt attacagcgg
    14941 gttttaacac cttatcaagt gtggccctag tcaaaacacc agatgtaaga acctatttac
    15001 tgattggagc tttactgaca acaggtagtg tgattgtgac ctggcttggt gaacagatta
    15061 ccgataaagg ctttggtaat ggggtgtcta tgattatctt tgcaggtatc atttcctcta
    15121 ttccaaatgc tattgcaacc attcgtgagg attattttgt caatgtgaag tcaggtgacc
    15181 tacagtcatc ttatatcgtt gttggtattc tcattcttgc agtgcttgct atcgtctttt
    15241 tcacaacgta tgttcagcag gcggaatata aaattccaat ccaatataca aagcttgttc
    15301 agggtgcgcc tacaagctca taccttccct taaaagtaaa tccagctggt gttattcccg
    15361 ttatctttgc cagctcgatt acaacaattc caagtacgat tatcccgttc tttcaaaatg
    15421 gcagagatat tccatggttg acaactttgc aaggaatttt taactatcaa tctccaacag
    15481 gaatgattgt ttatgccttg ttaattatcc tgttttcatt cttctatacc tttgttcaag
    15541 taaatcctga gaaaacagct gaaaatctac agaagaattc gtcctatatt ccaagtgtta
    15601 gacctggacg agaaacagaa gaatttatgt catccttgct aaagaaattg gcaactgtgg
    15661 gtgctatctt cctagcattt atatctcttg ttccaattgc ggcacaacaa gctcttaacc
    15721 tatcttctag tattgcatta ggtggaacta gcttgctgat tttgatttcg acaggtatcg
    15781 aaggtatgaa gcagcttgaa ggttaccttc tcaagagaaa atatgtcgga tttatgaata
    15841 ttacagaata gaatatgggt tgacactgtc aaccttctat tttgttttta aatgacaata
    15901 agatttacag agccttggtt cctatcttct tattgccatt tgaaaacaaa aacaaggaaa
    15961 actaaatttc ctattatctt tatgtcaaaa gaggagaaaa agatgaatct tttaatcatg
    16021 ggcttacctg gtgccggtaa gggtacacag gctgcaaaga ttgttgaaac ctttgagctt
    16081 attcatattt caacaggaga tatgttccgc gctgcaatgg ctaatcagac tgaaatggga
    16141 gttcttgcga aatcttatat cgataagggt gatttggtgc cagatgaggt aaccaatggt
    16201 atcgttaaag aacgcttagc acaagctgat attaaagaaa agggatttct tttagatggc
    16261 tatcctcgta ccattgagca ggcacatgcc ttagatgaaa ccttaaaagc attgggactt
    16321 acgttagatg gtgtgatcaa cattgaggtt gaccctgcgt cactcattga caggcttagc
    16381 ggtcgtatca tcaacaaaaa aacaggggaa accttccata agatctttaa cccaccagtg
    16441 ggagactata aggaagagga cttttatcaa cgtgaagatg ataagcctga aacagttaag
    16501 cgtcgcttag atgttaatat tgcacaaggt gagcctatta tcaagcatta tcgtcaagca
    16561 ggcattgttc gtgacattga cggaaacaag gacatttctg aggtctttgc tgacataaaa
    16621 aaggtcatcg aaaacctgaa ataaattcca gaaaatcgct tgcgaaagtg attttatcgt
    16681 gatatactag actagtctga cttataattg ttacctctgt gctcagagga catcaaatcg
    16741 aaatttaggg ggtacttttg cgtggcaaaa gaagacgtga ttgaaattga aggtaaagtt
    16801 gtcgaaacta tgccaaatgc aatgtttact gttgaattgg aaaatggaca tcagatttta
    16861 gcaaccgtat caggaaagat ccgcaaaaat tacattcgta ttttagtggg tgatcgtgtt
    16921 actgtagaga tgagtcctta cgacttgaca cgtggacgta tcacataccg ctttaaatag
    16981 tcgaaataat tggagggatt aaaacatgaa ggtaagacca tcggttaaac caatttgcga
    17041 atactgcaag gttattcgtc gtaacggtcg tgttatggta atttgtccga caaatccaaa
    17101 acacaagcaa cgtcaaggat aagatagaaa ggagaaaaaa tggctcgtat tgctggagtt
    17161 gatattccaa atgataagcg tgtagtaatt tcacttacct atgtgtatgg aattggtctt
    17221 gcaacatcta aaaaaatctt agcagcagca ggtgtctctg aggacattcg tgttaaagat
    17281 ttgacatcag atcaagaaga cgctatccgt cgcgaagtgg atacaattaa agttgaaggt
    17341 gatcttcgtc gtgaagtaaa cctaaatatc aagcgtttga tggaaatcgg ttcatatcgt
    17401 ggaattcgtc accgtcgtgg acttcctgta cgtggacaaa acacaaaaaa caatgctcgt
    17461 actcgtaaag gtaaagctgt tgcgattgca ggtaagaaaa aataaaatag gaggtaaaaa
    17521 aattggctaa accaacacgt aagcgtcgtg tgaaaaagaa catcgaatct ggtgttgcac
    17581 atattcacgc tacatttaat aacactattg ttatgattac agatgtgcac ggtaatgctt
    17641 tagcatggtc atcagccggt gctcttggtt ttaagggttc tcgtaagtca actccttttg
    17701 ctgctcaaat ggctgcagag gctgctgcga aatctgcaca agaacatggt ttaaaaactg
    17761 ttgaagttac tgtaaaaggt cctggttcag gtcgtgaatc agctattcgt gccctagctg
    17821 ctgccggtct tgaagtaact gccattcgtg atgtgactcc tgtaccgcat aatggtgctc
    17881 gtcctccaaa acgtcgtcgt gtataatcac agtaacaaat agtacacaag tttcgtttcg
    17941 aggggtgaaa gaatgattga gtttgaaaaa ccaataataa caaaaattga tgaaaataaa
    18001 gattacggta gatttgtaat cgaaccactt gaacgtggat atggtacaac tctaggtaat
    18061 tcacttcgtc gtgtactctt gtcttcactt ccaggtgcag ctgttacatc aatcagaatt
    18121 gatggagtac tacacgaatt tgatacaatc ccaggtgtac gtgaagatgt catgcaaatt
    18181 atccttaatg ttaagggact tgctgtgaaa tcatacgtcg aagacgaaaa gattatcgag
    18241 cttgatgtag aaggtccagc agaggtaaca gctggagata ttctcacaga tagcgatatc
    18301 gaacttgtta accctgatca ttatcttttt actattgctg atggttatac attgaaggct
    18361 tcaatgactg tcgctaaaaa acgcggctat gtaccagcag agggtaataa aaaagatgat
    18421 gcacctgtgg ggacgttggc agtagattca atctatacgc cagtaaaaaa ggttaattat
    18481 caagttgagc ctgctcgtgt aggtagtaat gacggctttg ataaattgac tattgaaatc
    18541 atgacaaacg gaacaattat tcccgaagat gccttaggtt tatctgctcg agttttaatc
    18601 gaacacttga atttatttac tgatttaaca gatgttgcaa aggcaactga agtgatgaag
    18661 gaagctgaaa aagtgaacga tgaaaaggta cttgatcgca ctattgagga acttgatttg
    18721 tccgtacgct catataactg cttgaaacgt gccggtatta atactgtctt cgatttaaca
    18781 gaaaaatctg agcctgaaat gatgaaggtc cgtaaccttg gacgtaagag tcttgaggaa
    18841 gtaaaggtca agcttgctga cttaggtttg ggactaaaaa acgataaata acataggagg
    18901 ataaaatggc ttaccgtaaa ctaggacgca ctagctcaca acgtaaagca atgcttcgtg
    18961 acttaacgac agatcttttg attaacgaat caattgtaac gacagaagca cgtgcaaagg
    19021 aaatccgtaa aacagttgaa aaaatgatta ctcttggtaa acgtggtgat cttcatgctc
    19081 gtcgccaagc agctgcatac gttcgtaacg aaatcgcatc agaaaactat gatgaagcta
    19141 ctgataaata cacatcaaca acagctcttc aaaaactttt ctctgaaatt gcgcctcgtt
    19201 atgcagaacg caacggtgga tacactcgta tccttaaaac agaaccacgc cgcggagatg
    19261 ctgctccaat ggcgattatt gaattagttt aatttttatc aattttgttg agtgttatga
    19321 tgatggagca gttcctttaa gctgttctta gtctagctct ggtctaccgc taggaccttt
    19381 cctagcggta acactcacca tgttgagaat aagtaacgct tgtttacgaa aggtctctaa
    19441 gctgtaggtg cccttcgtaa gcaggcgttt tgttgtgact ccatgttaac tgtagtagat
    19501 gactaatatc taatatctag agaggatcag cttggtgctc tcttttctga tattaaaagc
    19561 attgggaatc ttggttttga agttcttaaa gctcctaaag ccaaagtctt tcgcttgatg
    19621 tctttggtca tcttgttagt ggtctccggc ttagcattgg aataaggtag ttcaaagcat
    19681 tggtgatgta agatctatac ttcctgaagg tcttgaaaac cgttttgaag gtgtgattga
    19741 cctgtagcgg gagtagatta gatcaatggc gtttggctgc tttgaaaatt taggtgacaa
    19801 ttgtttttgt atctttgttt aaaaatggta taatattaaa acattaaaca aaatgtacat
    19861 aaaaaagcca tataaaagaa tgatattaag ataatgtgat caatagtttt agaaaatgaa
    19921 tgtgtaaggt taaggtatgc ccccttgata taatgctagt tttacgaaga ggcattctgt
    19981 acagacataa tgcactctta caaatgatac ggtaattgct caacaaggcg caacagcctt
    20041 ggcaaatgta atatttgcct tagctagcag cgaattagtt acgcttgata catagacaag
    20101 ggtttctggc atacagcagc agatggtgtg cctgtctcag agagtggctg cttggcttat
    20161 cctattcatg ttttaaaact tacaggaggt gttatgtggc ctttggtcga tggatattta
    20221 gctaggtgaa cagctattag ctgtaaatat gaggtaggag ctttagtttg catgatgtta
    20281 aatgaattga aacagactta ggaaagcttg gcttagcaac tatcacgcaa gttcttaaca
    20341 acgataaaga tcgtatggga aaatatgatc aagcatcaac ggacatgaga tgtgttttat
    20401 gaagaaacca ttatactttt ataagactta tttagttgtt tttctttgcg gacttgtttg
    20461 aggagtagtc tacataggca ataggctcag gcttacagca cttaggagac attagagcat
    20521 gagaagcact aactggctag tgatagaaaa gtaatagcac agtgttttta taactaacaa
    20581 gaggagtaga cattctatga gtattgacat gtatttgagc ttatctgaag agcaggcaca
    20641 gagtgtagag gctgtcttag ctaggcgaca aacagcctat caatccttac aggagacctt
    20701 gatccaattg atttctaaca gtcctgattt atcagggcgg acctatgatt ctgctaaggc
    20761 ttatagtagt caagtgctaa ttcctttgtt aaaggggtgt atgcttttag atgaggcgat
    20821 tataacagcc tgtaagaggc tacctagtga gtaccgtagt caggtagacc aaattgattt
    20881 gaaggagagt gatctggttg agcgtattgc ccagttcgat catgtgattg gtcggtacat
    20941 ggatttgatt agtattgaat acagtagaga ggagcctagc tattcttata tctctcattt
    21001 aagatcagct gagcagctcc atcgggccgt taagcggcgt cttgaggaga tattgcgaag
    21061 gctaaggcat tttgatacca actcagttca ccttttttcg actattcaga ctttggcagc
    21121 agcggtacaa ataggcatgc gtcaagctag gacctcgtgg catgcaggaa gtcaggtatt
    21181 tgtgatttca gaggatatgg catgggccga tacgattaat tctaagtggt caaaaagtaa
    21241 agggttaagc tatcttagtg attatgttta cgacccagat gtgctctcta agagagcagc
    21301 tattaatcac tcttggatta aaacaggcta tactatgtct aaaaattttg gcaaagctgt
    21361 ttcaaaagat tatacaaaag caagcttttt gagctatggt aaggcagcca aggcgactgg
    21421 ctggacttct atggcagtag atactggaat aactagtgta agggaataca ataagaaaaa
    21481 tagtagagcc tatggcagtg agggcaaggc gcttattcat gctagtgtgg ctcaaatcaa
    21541 gagcatggga cctatagaag gggcgataat tggcagtaaa gctggacctt ggggagcatt
    21601 aatggggttt gttacaggag gcattaatgt tacttgggga gtagtgcatc cagagtctaa
    21661 ggacaacatg tttttatgga tacaagataa aatggatgat gtttacgatt cgattgttca
    21721 gacagatctt ggcaaaggga cgcaccatgc taaagaaagt gtcaaaggtc atatcggtcg
    21781 agctattgta aggacatggg actttgtcag tcaatcattt ggtaaaggag tgggctatga
    21841 catttaaaga tcagcttttt agtgggacgt ttgagcaatc aaaaaagatt gtgtctaaaa
    21901 gtatattgac agaagaaggt gcgcagattg gagtattctc atctatgagt ctatggaaga
    21961 gaataacagg cttgatgatg ttgccattat ttgctatttc atatggagta ggagttgtgt
    22021 tacctgaaca ctttcaacaa tcaacagaag gagttcaagc tatttcattg gctgcaatag
    22081 agattattgc cagattagga cagttcagtc gatactttat catttgtttt atttgtatgt
    22141 ctgttggatt aattattagt aatatccttc caaagcctaa ctaggcttat caattattat
    22201 atggcaatgc tactcttatt atacttagta ttacaactat tatctcagcc ttccctttaa
    22261 ctgctggcct tacaattgca gcttttggct ggatcggttt tttgcttcag ctattgcttt
    22321 gcctttattt gtggaaggtt tgtgtcatag ataagtgtca acagctacgc acagcaattt
    22381 atcaagaaag caccatagca cctgattggg gcagtaagct agtaagcttt attaagtctt
    22441 atggtggtat cttattaggc ctctctgttc tcaaccgctg gactctcaat ctaggagagc
    22501 tagtcaagga aagccctggt ttgttgagtt ttctgtacgg ctggattttt ctattgttca
    22561 tgtttttgat gctatttgca ctgggtcaag cgttaaaaaa taccatcata gcctattatt
    22621 tttttagata tcaaaaagaa taccgcaagc attttaatat aagcgatgag cagtggtacg
    22681 gtaaatggcg tttaaaaata ttattaaaat aaacgatata aggagtaatc atatgcaaaa
    22741 agaattatta ccgttaggaa gtgttgtcta tctagaggga gcaacaagca agctaatgat
    22801 tgtcggacgt ggtcctatat ttgaatctaa tggccaaaat gtctacagtg attatgttgg
    22861 agtaatgtat ccagaaggga tcaatccaga agacgcgatt tttttcaacc atgaagatat
    22921 tgcaaaaaca gtctttgaag gcttcaagga cgaagaagaa caacgctttt tagaagtgta
    22981 ttctgattgg gagagtactt tagaaatttc caaaataaag ctatagatga actgtagcag
    23041 atatatttgt cagtagattg tcatgattat attgaaagat tatgactttc tctggcttaa
    23101 atacctctaa agttccaaag tttagaaaag gctttaaaat gagtgttata atagcattta
    23161 tgctcattaa ataaaggtag catttcaata gaatcggtaa aaaaa
//
LOCUS       DARYXZ010000036        22770 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYXZ010000036 DARYXZ010000000
VERSION     DARYXZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22770
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(92..562)
                     /locus_tag="TV186_001329"
     CDS             complement(92..562)
                     /locus_tag="TV186_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1532719.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            783..1633
                     /locus_tag="TV186_001330"
                     /pseudo
     CDS             783..1633
                     /locus_tag="TV186_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1969..2259
                     /locus_tag="TV186_001331"
     CDS             1969..2259
                     /locus_tag="TV186_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL1532720.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            2273..3412
                     /locus_tag="TV186_001332"
     CDS             2273..3412
                     /locus_tag="TV186_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532721.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            3409..3891
                     /locus_tag="TV186_001333"
     CDS             3409..3891
                     /locus_tag="TV186_001333"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL1532722.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            3888..4475
                     /locus_tag="TV186_001334"
     CDS             3888..4475
                     /locus_tag="TV186_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1532723.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            4472..4954
                     /locus_tag="TV186_001335"
     CDS             4472..4954
                     /locus_tag="TV186_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532724.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4979..5494
                     /locus_tag="TV186_001336"
     CDS             4979..5494
                     /locus_tag="TV186_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532725.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            6128..7762
                     /locus_tag="TV186_001337"
     CDS             6128..7762
                     /locus_tag="TV186_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532726.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7903..8796)
                     /locus_tag="TV186_001338"
     CDS             complement(7903..8796)
                     /locus_tag="TV186_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1532727.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8780..8971)
                     /locus_tag="TV186_001339"
     CDS             complement(8780..8971)
                     /locus_tag="TV186_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532728.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9206..10960
                     /locus_tag="TV186_001340"
     CDS             9206..10960
                     /locus_tag="TV186_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1532729.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            11101..11481
                     /locus_tag="TV186_001341"
     CDS             11101..11481
                     /locus_tag="TV186_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL1532730.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            11519..13852
                     /locus_tag="TV186_001342"
     CDS             11519..13852
                     /locus_tag="TV186_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1532731.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13901..14053
                     /gene="rpmG"
                     /locus_tag="TV186_001343"
     CDS             13901..14053
                     /gene="rpmG"
                     /locus_tag="TV186_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1532732.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            14065..14241
                     /gene="secE"
                     /locus_tag="TV186_001344"
     CDS             14065..14241
                     /gene="secE"
                     /locus_tag="TV186_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL1532733.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14632..15177
                     /gene="nusG"
                     /locus_tag="TV186_001345"
     CDS             14632..15177
                     /gene="nusG"
                     /locus_tag="TV186_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL1532734.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
     gene            16220..17737
                     /locus_tag="TV186_001346"
     CDS             16220..17737
                     /locus_tag="TV186_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1532735.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
     gene            18019..18882
                     /locus_tag="TV186_001347"
                     /pseudo
     CDS             18019..18882
                     /locus_tag="TV186_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            19471..21972
                     /locus_tag="TV186_001348"
     CDS             19471..21972
                     /locus_tag="TV186_001348"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL1532736.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            22159..22650
                     /locus_tag="TV186_001349"
     CDS             22159..22650
                     /locus_tag="TV186_001349"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532737.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYFDEGYSARQGINDLKS
                     LEN"
BASE COUNT         6698 a         4142 c         5054 g         6876 t
ORIGIN      
        1 tcaaggcttt tgcaggagat ttatgaaaaa gaaaaattta ggatagtgta agtataagct
       61 agtttcctta agaaaagctt aactgaagca attaatcgta gagatgggtg attgttttga
      121 cgactttttt ctccttgtca gaccaataat gaaggcgttc aaaagatcct tgtcgccagt
      181 agagtggtag cctttgtcga atatcctctt gcatgtctag cttatctaga tcagcaatag
      241 catgccattg tggtaggccc tctcgtgatt tagttagcag cttgccttca aaatcttcgc
      301 aaagaaagtc ataataaaca tagcgctcag gcttatcagg attggtaaag cctgagattc
      361 cctttaattg cagatttaag gcggttaagc cggtctcctc ctttagctca cgcactgccg
      421 cttcaaaaaa ggattctgag gtgttaacct tgccacccgg ttggatccag ccaggaaaat
      481 cgtcatgctg gcggttgaga agtaggatct tgtcgccctc cttgacacag atattaaccc
      541 aatttttgat gacttcaagc attagttacc tcgtttttag ttttatttta tcaaaaaaag
      601 atcagtatga atagctgaga gatttattga tatggtcata atggcttcag atagttttac
      661 tgctgcttta gccatctgca taaataatat aaaaatacca tttcacatca ttatttaata
      721 gatttattat catattaatg gtataattat gttaaattag aactatgtgt agagagagta
      781 taatgaatag tacagatttg atgagactgg gagagcttta taaggagctt cgtattgctc
      841 gtggacttag gctaaaggac gttgctagag acaatttatc agtttcacag ctatctaagt
      901 ttgaaaatgg ccagagcatg ctggcagctg acaaactact attagctatt tcaggaatcc
      961 atatgacatt cgctgaattt ggtcatgctg taaatgggta taaagtcagc gatttttttc
     1021 agttaggcac caaggttgcc gagctacaaa cagcatcaga tatagatgga ttgaaggagc
     1081 ttctgagcca atataagggt gatgacattt tttctgttta taatagatta aatgaattaa
     1141 tcattaaaag tgctatctac tcacttgatc caaatgttaa aattgaagaa tcagacaagc
     1201 aattgttgac agaatacctt tatagtattg aagagtggac ggagtatgag ctatacattt
     1261 ttggcggttg tttggctatt ttatctgatg aggatatgat ttttttggga aaagcattta
     1321 tcgaacgaga taagattttc ctttctcttc cacaacatag aaaggcagct cacatcactc
     1381 tcttaaatat tatcatgaca aggcagcttt ttatgttgat ttttttatta aaaagctgga
     1441 ggagttgatt atctatcaag atatgttcac tatagtgagc ttaaattttt ttaagaaaat
     1501 atatacctac ttaaatgaag aaagtaagca taagagcgac attgaagatt atattaatct
     1561 tgttaaacag cttggcaacc ctcagtttgc ccaaattcta catcggacgc tatcagtgat
     1621 tctagatagt taatactaaa aaagtagccc aatcgtttgg tggctacagt ggccaaggcc
     1681 accaaataga caaaagggct aataagaaaa taaaagcttt tcgcataata tctcacctcc
     1741 ttgataagga tattatacaa aggggaagct tcaatctcaa acattcgcaa atatgaaaat
     1801 attaacaaaa gcatcatcat atttgcgaat atcgagaata tgataattgt cgtgatataa
     1861 ttactgtgtt aatgatttag ctaggcatta ataaatctaa atatagacta caggcaggtc
     1921 gctcgttata ctagtttgag ggccaatggt ctgggtagga ggaagcgtat ggcgacatta
     1981 gagcgacatc ataaaatgtt attattgtca atggcattag gggcagcgag ctggttagca
     2041 ctcggattga ttagcttgcc aaatcttgca ggtgctttag gaataagtac tgctaatgcc
     2101 aatactacag ttaatttgtt gagtgcttat agtacagttt ctagcgttgt tgcaatcgtt
     2161 ggtgctgtta cgggtgtagg gtctattgga gctggaattg cagctaccgt tttatacctt
     2221 atcaaacaaa aaggaaaggc tgctgctgct ctctggtagt taattgtctg atatgaagca
     2281 tgttttcaaa tatcataaag gcgacatttt agggtatctc aatattgttg ggtttaccct
     2341 tttgttttat ggctcagtga taggtatgat aatgttcagg gattatttga cctatgatgg
     2401 agctggttct ctaatatcga cctttattct ggtatcagga acctatcatt ctgtgaaatc
     2461 aacatttcca tatgaaggga agcgtcatcc aacttttata ttaacaccct attatctatt
     2521 taagcatcta ttgctttcag ttacaaaggt ttatgctttc cagatccgag tggttactat
     2581 aggaatcatc tgtttagcaa tagcctttcc ggagcagctt gtttggatag ccttgtctgt
     2641 gctagcagta tttatatatt ggctatcgct tccgctagta gccatttttc gagtagctgg
     2701 acgactcctg aatcttctca tgatttatgg tatgtatctt aatcaggagc tgctggtcat
     2761 tgcttgtctt tgtttaaatg tggttattct tgtgcttagt gttacgatta atgtacatta
     2821 tccctaccaa tggctggcgg tgagagctag gaaggaagaa aaaacaatta ccttgttaaa
     2881 gcttgttatc aatacgataa cagatcattt agctttaatg gttctgttta gtattttctg
     2941 tatagctgtg acctatttca cgcaaaggct gctgctaagt tttgattatt ctagctttag
     3001 cataccagtt tttttcttat ctgcttctac ctatatcgcg ttactagagg ttatggtcgg
     3061 taaaaatatt aaggagcttg agttagaccg gggcttggct gttttacagt ttctgaatag
     3121 ggatatcagt gtttacaaag cttatcgcaa cagccaattc ttgctttctg ctcacatctt
     3181 agctgttatt catacaggat gtgccatagg cttactacca tttttactaa atggtcaagc
     3241 tgctcttttt ctgtctaacc tagtgatgat ccccttcatc tactttatat cattttgcta
     3301 tttcgtgaaa tcactaaaaa tagttgctgg tgatttgtca gtgtttaggt gggttattct
     3361 ggttttgtat tttatactag tggtcattgc aatggtaggt agtcgtttat gataatgagg
     3421 aaatttttaa gatattatat cagttttatt attttctcaa tagcaattgg gattttaatc
     3481 ggtttgctga tcaccagtga tactgtcata ttatctaagc cagagcgggg ctgggatttt
     3541 actctggagg ttttgaagaa taatagcaat aattttttgt cctatatttt cctcttcttt
     3601 ttgtccccag ccttgcaatt gattgatttg gtatcagttg ttatacaaat tactctagga
     3661 atgaggaagt ctggatttct aataactgcc ttgggtttgt ttccgcatgg tttgctggag
     3721 atccctaatt ttctctttta tcaaggcttg agtcaatata tgctatggac tgttttgact
     3781 gaaaaaagca tgacgtcctt cttagaaaga gaaagaagat atgtaaggta ctatcttata
     3841 tcgtattatg ttttgttaat tgctggtatt atggaagggt tactcggatg aaaatagtaa
     3901 atgaaagcaa gtcattttca aacagaaaaa tcttaaatca catatccttt gactttagta
     3961 aagggctgta taaggttgaa gggaataatg gtagtggtaa aaccactttt ttgcgcttgt
     4021 tagcaggctt agaacggttt gatagcggcc atcgcttaca gcataaggga gatattctat
     4081 atcttgatac taatgctatc ggtgtagttc ccttaactat tgaagacaat ctgacattat
     4141 tatggaaaac ctttaatgcc tctcctgatg aggagacctt gtctgtgatt aatcagttct
     4201 ttggagaacg gttactagat cattatctga cggcttctgt aggaacaaag gctaaggtgg
     4261 gcttatcctt gctttttgta aaggattggg attatatttt catagacgaa gccctatcaa
     4321 cgcttgatgg gtttagtctt gatatggttg caggaagatt attagcatta aaagaaaagg
     4381 ctactgtttt ttacgtttct cataatctat cacaccagca gctattgtca gaatcacagg
     4441 tgatttatct taatggaaaa ggagaaatct attgaaaggt aatcctttta atcgtaatct
     4501 ttcttggtta atagcctatg tgctattact ttcttgttat gtattcatat tagtagatgg
     4561 tggtttttta aaaaacagcg ttcaagaatt ggaagtcctg ctcggccaaa catcactagc
     4621 tataaagctg tttttgatgg tgatatcaat agcttttagc atcatatctt tactggttga
     4681 gtatttttta agcaaatttt tagtgctgct ttttattgaa gctggcatcg tttctttaaa
     4741 tgatgttctt actgctaaat cagtgacttt agtgatccat ttatctgctt tgctattgaa
     4801 gctatctccc tctccacttt ttcagtttgt agtgaatgct ttagggattg tgatcatgta
     4861 tggattgagt atcaagagac aaggaaatag gacaactgct cttttgtttt gtttaccctt
     4921 tacactggat attctagcaa cattgttgct ttagtgattt tgagttggag gaaaagtaat
     4981 gaaaaaaatc ttatatttat cagtactttt aggaacgtca attctagcaa cattgattaa
     5041 aatttataac actttttttg caaagctaaa ggcttcatca ggtcattcaa ctgggaatat
     5101 agagattgat gcccttttat ctgagtctag actagtgttg gaaaggcagc atgccttcac
     5161 aacaaatgga atcaacaagc tattcgttat gatgatgagt ctaatgctgt tattagcctt
     5221 atactatctg ataaaaaagg atttgaaggc cgtctatagt tatttgcttt acctggtgtt
     5281 aaccttggtt catgcaattt atagcttctt ttcgttaagt cccttggcaa agctttattc
     5341 tgatgatatg ctgggggcta caatccagac gggagagaaa gctaaattga ttttttcagt
     5401 ggttcttttt cttctttatc tgcttattgt tgtggccaat aatagagtaa aatctagtgt
     5461 agaacccgct tcatctattg ggatagatgt gtaatacctt tcatattatg acctttaaag
     5521 ccttttagct tctctaattt tcagagtaac taggaggctg tttgtgacgc tctgagcgtt
     5581 ttttcgtttc tatcaaagtt tagctgcgtt aatgctatct atttccgtag ctgagataca
     5641 agatattata atatgtgttg tcataccata aaaacacctt acaggatatt ttatgatcaa
     5701 tcctccttga attaagcttt ctttaagcaa gggtgtgtat actagccgta atcctaaata
     5761 attggttacc taatgataac taattttttc ataacctcct tcctaaaaac gatgtcaggg
     5821 cagtcaggat tgattgctgt tatggcatcg tttttgttgt actttgatag gggatctagc
     5881 tgtatgttaa atagcctatc aggattgagt ggcgaagatg atcaggagtc tcttggctct
     5941 aggttatgct gctgtttcat gagaaacagc tcttgatgat caatttaggt agtattagtg
     6001 gtggtcatct tagcctttta ggctttgagc tgctttatgt ttgctcattt ttaatatgtt
     6061 agtgtttaca caaataattc tcattttttg atataataga aaaggtaagg aagggtagga
     6121 gataaggatg acaagatttt ttcaaaaaaa acaggccaaa agcttagcca ttggttttgt
     6181 gagcttgttt gctgtgctca ttgggtatgg agcttttcac tattctaagg ccagtcgtat
     6241 caatgcctat ctacaagcaa ggtcatcagg ctctgggcag gtgcttgaaa atatcaagga
     6301 atacctcgtg tgggcagata ccaatgagca gctgaccaat gatcaagcaa gatacaccag
     6361 ctttaagaga tacagtaagg cagagctagt aagcaagcgt cagcagctgc aaacagcaac
     6421 tgcagctgat gatatgtatg tcaaatcggt tggtcgcaaa tttttgattt tccctgatta
     6481 tcgcatagca gtgaagcctg tagccttgac aatcaagacc aatgtgccaa atgttgatat
     6541 cttgttgaac cataaaaaga ttgctgtatc acagtcagag gattttagca caactattga
     6601 aagactgccg gctgctgatt ataaggcgag tattaatggc tattataagg atcgtaagat
     6661 taaagtcagc aaggcctatg atggcaagaa ccatacacta gatttgaggg ttacctttaa
     6721 gacatttacg gtaaccagca atgtcagaga tggcgagctt tatattgatg gcgagcgcgt
     6781 ggaaactttg aaggctgggc agcttcagct ggaagaatac cctgtgacag aaatcgcaaa
     6841 ggcctatatt aaaaagacct ttcctgatgg cgagctaacc tccagcaagc attcccttgc
     6901 tcctgttgct gagggctccc agctagagat taacattgat cacctcttga ctgaggaaca
     6961 ggcgggacag gtgttggtgg cagcctttga tcaattgctc acctatctca atcaagggca
     7021 ggatccagca ggtctttcaa ctgtttttga gcaaggggct aataatgctt tttacaaagg
     7081 cttgaaggat tccatcaaag caaaatttca aactgatacc agaaaggctt ctcggttaag
     7141 cattccgtct attttgttaa gtaagctaac tcaaattggt aagcagtctt atctagtgga
     7201 ctttacagct gtttatgatt ttgtttacga taaggaaact gatcctgaaa aaggcacctc
     7261 agggaatgtt cgtcaagact tgactggtaa gctgaccctg aaaaaatctg gggatagcta
     7321 ccttgttagt cagtctggtc ctaaaaatat tacagttgcc agcgaaaaaa atcaggtcaa
     7381 gccgtctatt ttcccagagg ggctagtggg aacctggata ggacatcgtt cggacatgac
     7441 ctttacgatg atattggcta aggacggcag catcacaaca accattggaa acaaaaatgg
     7501 gaatggctca cagaccacta agtctgctaa aattaccaag gtagaggaaa aaggagatgg
     7561 cttgttcctc tacactgtag ctccagatgc tgatatagca gctcttgttc caggaggtgg
     7621 attgggtggt gtcaatgtca aatacgcttt tggtgtcaaa tggagtggag atgtcgctac
     7681 gatagtggtt tggcagacag caaataatgc ggcatttgat tacagtaagc caatgcttgg
     7741 ccctgacatg aaaaagcaat aagtacttta ccctacaagt tggtctagca tttattgcta
     7801 ggaggaatca gcataaagaa aaagcctctc ttttaatctt ttgtggttaa gaagagaggc
     7861 tttttagtat agggctgact gtatgaggag caaccgatgt aatcaattta gctgctgtag
     7921 tccttcttta aagcttttag acggggcagt gaccctaatc atctcttgag ccaaggggtg
     7981 tctaagggtt agctgatgag cgtgcagcat gagacgctcc gctttttgcc tgctatagag
     8041 gggatcacca attagagggt gtttatgatg agcgagatgt actctgattt gatgtgttcg
     8101 tcctgtctct aggcgacagt tgactaggca ggtctgatca aaggcttgta ataaggctag
     8161 atgggtgatt gcctcttgcc catgcttact atcaaccaca cgcttgcgcc tatcgtggcg
     8221 gtgacgtccg attggatcgc gataggttac tgtttgctgc tctagctgac cttcgattag
     8281 ggcccaataa tctcgcttaa tgtctcgatg ctccaatagg cgatttaaga tcggaaggat
     8341 aaagggattt ttagcaaaga gaatcgctcc actagtctcc atgtctaagc gatgaaccac
     8401 atagcaggtc ttgccagtat aggcagagac atggttgagc aaggcgagct cagtgggctc
     8461 attgccatgt gttttcatgc cctcgggctt gttgacaatg atgaggtgtt cgtcctgata
     8521 caggcaatcc actaggccag gcttacccat taagatgcct ttatcagggt agtcttcttg
     8581 gtcaaattgt agcttgatgt gatcaccctg cttgacaggg ctctgccagt taatcagctc
     8641 atcattgacc caaacatgct ttttgatgcg caagaaatgt ctgattttac ggggaatcaa
     8701 tagcctatct tctaataact ccttgacagt tgtcgcttga taggggttaa tgaaggagat
     8761 ctgaaagccc atctcaggct tatttgctgt tgtcattgag ccagtcatgg tatttttcaa
     8821 tcaaattgat ggccatttgg gttgcaagag ttacagagaa agcctcggtt ccctcgcgct
     8881 cgtcactggc aacctctaag cgtgtctcat catagacagc cttgaggctc tctgctgaca
     8941 gggtttcttt aaaagcttga aatttgttca tgatcatgtc ctacctttct aaatgtttgt
     9001 gacaatgcta ttatagcata tttttcatca aagctaatca tttgctcgat gatttgtgct
     9061 gcgctaacag cgtgattctt ttgagaaaaa ataagattag ctattgtgaa attgtctgtc
     9121 ttttattata ctaagaatag tctgataaat atattattta aggacacgat aacattggga
     9181 ttatgaatca tttaggagaa tactattgaa caagccattg ataaaatcct gtttgcttgc
     9241 tctattgacc ttggccggct tgaccagtat ggcagcacag gctgatgtca acacttacaa
     9301 ccaaggtagg acatataacg atacacccta ttattctgct tatcatcact actatgacca
     9361 cacgagggat actgctgaca atggtattga taattggggt cgtctgacac gctatcacta
     9421 ttacagagag acctattatc agcttgaggc cgagcgtcag cagcttgtta ggacttactt
     9481 ggagttgaag gcttcatatg atgatcaggt ggctcttagc agtcaacgac tacagcagta
     9541 ccagtctggc tggtctgatc tccaatcacg ctttgagcag ctcaggaaaa ccaatcctgt
     9601 tgtaggcggt gattatcgga ttgttgagct agagggcaat tttcaaagct atcagacctt
     9661 gctgcagcag ctttctatgg ctgattttgt cagccagtac aaagataggc tggatacctt
     9721 gactagactt gatacagagc gagctaggct cattgacacc tggtgggaaa gtgatagcaa
     9781 ttactcagat ctcaatacca atctaacact agtcaatggc tatatcaagg agctgaatca
     9841 ggctttacag gagcttctta aggaccatca aggtaaaatg acatcagatc tgcagacctt
     9901 gggtgaccga caggccgagc ttgctagacg gctgacagat atagaaagca ggcctaagag
     9961 acaggctacc agtcaacctc gtggttcaca gacacattgg cgatcagccc ctagagctga
    10021 tgttgccttg tggaatgaat tgcgaaacga aggagattat gcttctgcta cgacagacaa
    10081 tgctttgcca ttgcagcctt atcgagcgga cttaacagct gttcatgatc tagaagcctt
    10141 gcaagcacaa tctgatagag cacaccgctt gcgggcaaag gaaattgtct ttacactgca
    10201 gcgttctaac attagtcgtc agggcgatat agatttgtca ggagccatta cagcatttat
    10261 caaagaaaag cttctcgtca ctccaaatgc gcgtggggta tcatctggct ttaggtggca
    10321 aatgcaaacc tatgacaatg agcgcttaac catcactcta atgcctcaat attatatgac
    10381 tgatgatcag tacaaggagt attacgacca tctcaaggct tggacagctc agcatatcca
    10441 gtctaccgat acagaggttg agaaaattga taagattcaa gactatatca tgacaaacta
    10501 ccactatgcg accggcaagg ttggaggagt gacccgtact ggcatttctg tgcagacgcc
    10561 atatgccttt atcaaggaca aggaggctgt ttgtcaggcc tatgcacaga tgtttaagga
    10621 catgggacga ctagctggac ttgatgttca ttatattcaa ggctatggag acccagttgg
    10681 cggcttatca agtctacatg cttggaatat cgtcaaggtt gatggtcaat attatcatat
    10741 tgacctgact tggaatgata ctattgacag caccaatcac aatcatacct acaccctgcg
    10801 aggcaatgat tttatgagca aaacacattt gtggaatgct gcctatgcga tctcagatag
    10861 tgactatgct gcttatccta ggaggagctt cctgagatat gggacctatg cgactaacta
    10921 ttcaagaaat acattttatc caggatacag ttatgcttaa taatagctaa taccatcaaa
    10981 agccctagaa agcttgcttg attctttcag ggctttttga tatgtcatgg tttttggtat
    11041 aggattttga aagaaattgt tataatagga taaaatgctt atgtaacagg agaaaataaa
    11101 atgaagagta ttagacgcta tgatgtcaat gaagagtggg cacatactgg cttagtagag
    11161 gcaggcgatt tttatttttt aaattattgt gtaggaaatg tcggtcaaga tattgaggct
    11221 caaattaacg gtgcctttga tgaaatggag cgtcgtttgg ggctggtagg gctgacgcta
    11281 gaggtcgttg ttcaaatgga ttgcttgttt agagacattt ggaatgtgcc agttatggaa
    11341 aaaatcatca aggagcgatt taatggcaaa tacccggctc gtaaatttct tcaaacagcc
    11401 tttgctcatc agggtggtcc ggacggcttg ctatttcagg tagatggggt tgcttattca
    11461 aagcatatct ccgtatccta aacaatatga cttggaggct tagtagtatc ataaggctat
    11521 gacattttta gaattattac aaaagaaatt ttttccaaaa aaataccaag aaaaacaggc
    11581 cttaaaggaa agggcagccc agcatatggc tgacaaagag gctactactc aggctactgc
    11641 cactgctttg gccgatcagg aggcacaggc agggcagact gagaggcaat cagtccttca
    11701 acgcagcaag tcctatgggg tcaaaaggaa aaatcggccg atctggcttc aaaggctgga
    11761 ggcgattttg ccatcgcagc aaggtcctat tcgccgcttt cttcgtcgtt accatgttgg
    11821 taaaatcctg ctgattttga tgggtacctt tgtcttgctg ctggggtctt acctttttta
    11881 cctttcaaag acagctaagg tttctgactt gcaggacgct cttaaggcga cgacagtcat
    11941 ctatgaccgc aagggagaat atgcaggcag tctttctggt caaaagggga cctatgtgga
    12001 gcttgacgct atttcagatg atttggaaaa ggcggttatt gccacagagg accgtacctt
    12061 ttataccaac aatggtatta atttcaagcg ctttttattg gctattgtga ccgcaggacg
    12121 ctttggtgga ggctcgacca ttactcagca gttggctaaa aatgcttatt tgtcccagga
    12181 gcagagcatt aaaagaaagg cgcgtgagtt tttcttagca cttgaattga ccaagaaata
    12241 cagtaaaaat gacattttga ccatgtatct caataattcc tattttggaa atggtatttg
    12301 gggtgttgag gacgccagtc aaaaatattt tggtacctca gcagctaatc taaccttgga
    12361 cgaggcagca acccttgccg gtatgctcaa gggacctgaa atttacaatc cctattactc
    12421 aatcgaaaag gcaaccaacc gtagagatac tgttttgtca gccatggttg acgctggaaa
    12481 aatcagcaag cagcaggcac aagaggccca agctattggt atggggaacc gtttagcaga
    12541 cacctatgtc ggcaagacag atgattatca gtacccatct tattttgatg ctgttatcaa
    12601 tgaggctatc tcgcgctatg gcatctcaga aaaggatatt gtcaatgatg gctacaagat
    12661 ttacacagag ttggaccaaa attaccaagc aggcatgcag accaccttta atgaggatag
    12721 cctatttcct gtgtctgagt ttgacggcag ctcagctgag gcggctagtg tggctctaga
    12781 tcctaaaacc ggagctgtca gggggcttgt tggtcgtgtc aatagcacag aaaaccagcc
    12841 ctttagaagc tttaactatg ctactcaagc caagcgtagc cctgcttcaa cgatcaagcc
    12901 cctagttgtt tatactcctg ctgttgcagc aggctggtca ctggagcacg aactgccaaa
    12961 cagcgttcag gattttggcg gttatcagcc gcataattat ggcaattacg aatcagaaac
    13021 aattcctatg tatcaggctt tggctaattc ctacaatatt cctgctgttt caattctgga
    13081 tcagttgggg gtggataagg cctttagcta tggtgaaaaa tttggtttga agatgagtga
    13141 aaccaaaaag gagcttggag tggcgcttgg tagtggtgtc accaccaatc cgcttgagat
    13201 ggcacaggcc tatgcagtct ttgccaatgg tggtgtcaag catattgccc acctgattac
    13261 cagaattgaa aatgctaagg gcaaggttat caagaccttt acagacaaaa ccaagcgggt
    13321 tatcagtcaa tcagtggctg ataagatgac tagcatgatg cttggaacct tttctaatgg
    13381 tacagctgtt aatgccaatg tctatggcta tactctggct ggtaaaacag ggaccacaga
    13441 aactgacttt aacccggacc tttccggtga tcagtgggtc attggctaca cgccagacgt
    13501 tgttatcagt caatgggttg gcttcaatca aaccgatgag catcattatt tatcagattc
    13561 aagtgcgggc actgcctcag caatttttag cacccaagcc tcttatatat tgccatatac
    13621 caaaggaagc caattcaagg tcgataacgc ttacgctcaa aacggtattt cagcggttta
    13681 tgggattaat gagaccaata cgcaagcagg tattgattct caatccatca ttgatagtct
    13741 tagaaagtca gccgaggaag cttcaaagtc tatttcagag gcagttgatc aatctggtct
    13801 cagagaaaag gcgcaaagta tctggaagag tattgttgac tactttagat agcttgcgaa
    13861 aatatctaaa tcgtgttaga ataatcacta cggaggcgtt atggcacaga aaaaagcaag
    13921 cctagcgtgt gtagaatgtg gcagccgcaa ttattctatc gggattagta gcacgcctag
    13981 accaacacga ctagaagtca ataagttttg caaatattgt aaagcataca ccttacacaa
    14041 agaaacacgt tagaggagag cctgatggga ttcattagtg ggatttttaa gcttttaagg
    14101 gatacaactt ggccggatcg taagcagcgc tggaaggact ttatttctgt ccttgagtat
    14161 acagcattct ttacggtaat catctttatc tttgaccagt tgctatcaaa aggcatttta
    14221 tcattgatta atttattcta agtcattgca atgatgagac ctgttatgat taaaattgct
    14281 tggaaaagcc taggctgaaa caatcgtttc ggcctttttg agtgcgatgg gcaggttgta
    14341 ctctgataga tgcaagacca atagaccacc tactatgcgg gtgcgtaaag gggttgatag
    14401 ctaccgatag ttaagggcta tagcaagtag aaaggcttgc agctcagctg atccgctgtt
    14461 atgactaaag gcattgacca gaaaggttcg ttggcagcca acaaagtgct cttaccctgc
    14521 tatgaggggc tattaatgcg ttgacagcca atccttcttc tattataatg aaagtgtgat
    14581 aacagcaatg caaaggccag cagaggcttt tttataatga aaggaagtaa catgttagat
    14641 tcttttgata agggctggtt tgtccttcaa acttactcag gctatgaaaa taaagtaaaa
    14701 gaaaaccttt tgcagcgtgc tcaaacctat aacatgctag acaatattct ccgcgttgag
    14761 attcctaccc aaacggtaaa tgttgaaaaa aatggtcagg tcaaagaggt tgaggaaaac
    14821 cgcttcccag gatatgtttt ggttgagatg gttatgactg atgacgcttg gtttgttgtt
    14881 cgtaacacac caaatgtgac aggctttgtc ggatcgcatg ggaaccgctc aaaaccaacc
    14941 cctctacttg aagaggagat tcgtgctatc ctgttgtcaa tgggacaaac tgttgatgtc
    15001 tttgatacca acattaaaga gggcgatatg gttcaaatca ttgatggcgc ctttatcggg
    15061 caagagggtc gtgtcgtaga aattgaaaac aacaaggtca agctcatgct taatatgttt
    15121 ggctcagaaa ccttagcaga ggtcgagctt taccaaatcg cagagctatc gtcctgatag
    15181 gctcctaaag ctattattca taccataaaa aataaaaggc tggcatcggc tctctaaaat
    15241 accgatgtta ggcctttttt gttggtcttc tacaaccaag actcaaatta accaaaccct
    15301 aaaaagagtc atttttcctt cgctttttaa gtctctaact gatcgcccta gcttattttt
    15361 aatctagtaa tcgcaacagg tcaagagtta aatgatatcg cgccgttatt gattggtata
    15421 gacaaaaata cgctcaaaaa aagaaaaaag gataggtaat atagtcctgg tttgcttgat
    15481 agatggtggt tggcaaccaa ccattcgagt actttcctta actataaact cctaatcaat
    15541 tctagcgttt aaaaaataag attattcttg gagggaagca aagagcttct ctcctttttg
    15601 agttgtagca ttcttgatcc tgatcttata agcagagtcc tgtttgccgg gctgttgaga
    15661 tgaataaggg catttctata gtgattatat agtgttgcag atgtgtgtat ggtttaaggt
    15721 ctaaataccc ttcaagctta gttcttgggt agtcagttcg gattggctgg ctgattttta
    15781 agcctttaat ggcttagtgg taagacaaac cagattacat ttgctaaaaa gtccctaagg
    15841 ctacaatcat tttttgtgac taatataaaa actagacctt ttgggatttg taataattta
    15901 gattattgtt tttaaaatta gcaaatatta aacgcttttt tattgaagat acagatgata
    15961 gtaatggcag agctaaaaaa taagagaaaa taaaaaaagt ctacaattta taatgtaata
    16021 aaaaaatgag ttgactgttg tgttttaaag gcttttgtct atttgtaatc ggttaatttg
    16081 caaacaattc taaggtattt ctggctaata gtatgctata atgtaatact gttctacaac
    16141 cgacattaag agttaatgaa atagtgttgt gttgtggtaa gtttttaatc aggaagagta
    16201 tatttaggag ctagatacca tgtctataga gaatctcttt accaagcagc agtggcgaga
    16261 gcttgagttg attactttat taagtgaaac gaaaaatcca ttatattata aagatgcttg
    16321 tcagatgctg gattgttcgg ttttaacgct gcaatcgtgt atcacgaatt ctgtttttat
    16381 ggaagattta ggcaagctgt tctacaagga ttctcaattt catattcatt acaatcatca
    16441 aagtggctta aaggaggttt atcggagagc cttgctagag tctccttctc ttcagttgat
    16501 gtcggccttg ttttttgatg attttgcgtc attagatgat cttgcagagg cactttttat
    16561 tagcttgtca accttaaagc gcttgattcg taaaaccaat ctctatttaa aagagcattt
    16621 tgatattatc atttcggcta agcccattcg tgtagttgga gatgaataca atattagact
    16681 gttttacatc aagtattttt cagaagcata taccttttct gaatggcctt ttgcttctct
    16741 acttaatgaa aaccaccatg agcaatttgt tcaattaatg gcatctttga tagaggttaa
    16801 gattgatttt gcgatttttc gtcaactcaa gctattaagt gcggttaatc tcattcgcta
    16861 cctcaaaggc tttaaaattg ggaagcataa agcactgagt agtctttcat tggagttgtt
    16921 acaggattct caggagatga aaaagctgtc gcatttgttt gtgcttaaat tttcagtacc
    16981 gcttgatgag cttgtcttgt cagaaatgtt ttccaattat ttagatgatg atttggtatt
    17041 agaaaaatcc ttgcaggtag ataaggttaa ggaggaggtt ccgggtcctc agtccttgct
    17101 gagctggata gatttgctta gtgaaatgga gggagctaca ggtattgtat tgccaaataa
    17161 atatgaggtt gccagatatc ttcatgccac tgttatttta ggagtggagg atattagtga
    17221 aagctttctg atttacgatt ataaaaagga ttacttggcc ttctttaagg agcattatac
    17281 ctatgtttat tttaggttta ccgattatgt gaagaggcta tttaaggacg gggatatgga
    17341 gcttgctact aatttgctca acaatttggt ttattccttg ctgatagcct gggagaattt
    17401 ctttttaacc atgtgtgaat tgatgaaaaa accaaagctc ttgattatag aaagaagtca
    17461 tggcagtacg ggaagctttt tgaaaaaata cattggtgaa ttttttgaga ttaccatttt
    17521 tgataaatta accatagaag ccttgtgtct acagcatgac tatgacgtca ttattactga
    17581 tacggtcatt aggggctgtg agcatgctga tatctttttc tttagtcgat ttgtgccaac
    17641 cgttatagtc gccaagctta accattatct aagaaaacga atgggtagta tctttgaaac
    17701 gaaaacaact aacaagcttg ggaacatcgg ctattgatag atatcggtat atttcattaa
    17761 aatagccaca acttgtcatg gtgtaaaatt agtgagcttt gttaatccaa taaaattagg
    17821 tagaatatag ctataggcca acgtgtaatt cccttaggga gtaggtgctt tggtctggga
    17881 aagagaaaaa taaaaaggag aaacaaacaa catgaagagt tgtaaatcaa ccctagttta
    17941 gataaaaaga ttaattcttc tattggtatc aaaggaagta attttatttc ctcaaaactt
    18001 ttagcgaatt taaagactcg catcgactct gaagctactt tgaaagcaga aacaactcaa
    18061 ttgaaagccg atatagaaag agaaaaactt acttctaaag aattaagcac taaactggaa
    18121 gaggtaacat cagatcgtga taatgctctc agtgaatctg ccgatcttgc caacaaactc
    18181 tcagtagctc aagcagaagc agatcgttta agtcaggctg ttgatagtct gggtcgattg
    18241 actaactctg ctaagcgtga gctcacagag aagcttgctg agattgatca attaacacag
    18301 gacaaggtta aagcagagac tgaccttgaa actgctaatg ctaacatcac aacacttcaa
    18361 gaggagctgg caggtgctaa ggctaatgtt gataagcttg caaaggaaaa agctgcggca
    18421 gatcaggcac ttgctgaagc taatgcaaga gtatcaaatc ttgggcaaga ggtagcagca
    18481 gctaataata gagtggctga ccttgaagcg caattagctg aaaaaacagc cgagcttgat
    18541 gtggttaagg cagacaaggc agagcttgag gctaaggtta aggagcttca aagcctgctt
    18601 gagcaaaagg atcgtagcaa tgctgatctt caagctaaca ttgagcgctt gaagcaggag
    18661 cttgctgaca agtttaagga tcaggcacag cctcgttcta agactcctca ggcatcgaac
    18721 tcggttgcaa agcaaaaagc aagtaagcca gccgcaaaac cagcaggcca gctaccatca
    18781 acaggtgaag ctactgcaaa tccatttttc actgctgctg cagttgcgat tatgacaagt
    18841 gcaggcctag taacagtcat gccaaaacgc caaaaaaatt aagctattct caattctctc
    18901 ccctttaact attgttttat agcattttac taatggacat tggcattcct ataaactcta
    18961 ttgagcttct tatctgatag caaggataag gggcttttta gtagcttagc aagcactcct
    19021 tggtcaagct caatacctct ttgagagctt aaaactagag ctagaccaga tctaaaacca
    19081 agtgagatga tagcggatat ttggctgttt tatgagttgg ctcgtaaggc ttgagcttat
    19141 gcgtcgcaga gacgcgctat ctagtctaaa gggctttagc aatgtcgtga caaacgcatg
    19201 aagacagtta cactttctca tagcgagttt ttatcatcag tatagttttt ttggcaatat
    19261 gttatgaaat agtcaaatag caatcgagaa actggtgata ttgcaatgca aaaccgctga
    19321 acatagatta aaaaaatgca tgcagctaga aaatggttac atgcattttt gtgatgccga
    19381 cgtcgtggca gcaatattgc ttgcccattc ctaaaagtct gatatcgtgc tataataaga
    19441 agactagact ttttacatgg gagaattcac atgacatttt acaatcacaa agccattgag
    19501 cctaagtggc aggccttttg ggctgataat cataccttta aaacggggac agatgcctca
    19561 aagcctaaat tttatgcttt agatatgttt ccttatcctt ccggtgcagg tcttcatgtt
    19621 gggcatcctg agggttacac tgcaactgat attttaagcc gcttcaagcg tgcacagggt
    19681 tataatgtcc tccacccaat gggctgggat gcctttggtc tgcctgctga gcaatacgcg
    19741 atggatactg gtaatgaccc tgctgagttt acagcagaaa acattgccaa ctttaaacgt
    19801 cagatcaatg ctcttggctt ctcgtatgac tgggatcgtg agatcaatac aactgatcct
    19861 agttactaca aatggacaca gtggattttc acaaaattgt atgaaaaagg cctagcctat
    19921 gaagctgagg tgcctgttaa ctgggttgaa gagctgggaa cagctattgc gaatgaggag
    19981 gttctccctg atggcacatc agagcgtgga ggctatccag ttgtccgtaa gcccatgcgc
    20041 caatggatgc tcaaaatcac agcctacgca gagcgcttgc tagcagatct ggaggaagtg
    20101 gattggccag agtcgatcaa ggatatgcag cgcaactgga ttggtaaatc aacaggggct
    20161 aatgtaacct tcaaggtcaa agataccgat aaagacttca ccgtctttac cacacgacct
    20221 gataccctgt ttggtgcaac ctatgctgtt ttggcaccag aacacgcctt agtagatagc
    20281 attactacag cagagcaagc gcaggctgtt gctgagtaca aacgccaagc gagcctcaaa
    20341 tctgaccttg ctcgtaccga tcttgccaag gaaaaaacag gtgtctggac aggagcctat
    20401 gcgatcaacc cggtcaatgg caaagaaatg cctatctgga ttgcggatta tgtgcttgca
    20461 agctacggta caggtgctat catggcagtg ccagcgcatg atgagcgtga ctgggcattt
    20521 gcaaagcaat tcaatcttga gattattcca gtgcttgaag ggggcaatgt tgatgaggct
    20581 gcctacacag aggacggtat tcacattaat tctgacttcc tagatggtct tgataaggct
    20641 tgtgccattg ctaaaatggt ggcgtggctg gaggagactg gtgtcggtca tgaaaaggtc
    20701 tcttatcgcc tacgtgactg gctgttcagt cgtcagcgct actggggtga gccaatccca
    20761 atcattcatt gggaggacgg tacctcgaca gcggttcctg agcaggacct accacttgtt
    20821 ttgccagtga ccaaggatat tcgcccatct ggtacaggag aatcaccact agctaacttg
    20881 actgactggc ttgaggtgac ccgcgaggat ggggtcaaag ggcgtcgtga gaccaacacc
    20941 atgccacagt gggctggctc aagctggtat taccttcgct atattgaccc acacaatgat
    21001 gagcaattag ctgataagga cctgttaaag caatggctgc cagtagatat ttacattggt
    21061 ggtgctgagc acgcagtgct tcatctgctt tatgcacgct tctggcacaa ggtactctat
    21121 gatctgggtg tagtgccaac caaggagccc ttccaaaagc tctttaatca aggcatgatt
    21181 ttgggaacca gctatcgcga ccatcgtggg gccttggtcg caacggataa ggttgacaag
    21241 cgtgatggta gcttcttcca catggaaaca ggcgaggagc ttgagcaggc ccctgctaag
    21301 atgtctaaat cactgaaaaa cgttgtcaac ccagacgatg tggtggagca gtacggagca
    21361 gataccctgc gtgtgtatga aatgtttatg gggccacttg atgcgtccat tgcttggtct
    21421 gaagaaggcc ttgagggagc acgcaagttc ctagatcgtg tttaccgttt gatcacgaca
    21481 aaggaaattg ttgcagaaaa tagcggagct ttagataagg cttaccatga gactgttaag
    21541 gcagtcacag aacaaatcga aggcatgaaa ttcaatactg ctattgccca gctcatgatt
    21601 tttgtcaatg cagccaataa agaggacgag ctttatgtgg catacgccaa aggcttcgtt
    21661 caattgctag ccccatttgc cccacaccta ggtgaagaat tatggcagat cctgacagct
    21721 tcaggtcaat ccatctcgta tgttgcatgg ccaacccatg acgatagtaa gctcgttgaa
    21781 aatgatgttg aaatcgttgt tcaaattaaa ggaaaggtca aggctaagct tgtcgtggca
    21841 aaagacctct caagagaaga gctagaaaaa gtagccctag cacatgataa aatacaggct
    21901 gaaattgcag gcaaggaagt ggcaaaggtc atcgttgttc ctaataagct cgttaatatt
    21961 gtggtgaaat aaagacccta gcaaaaaatg ccttccttat aattttgagc ccaatactat
    22021 aaaaagctga taaccactcg tttacatgag tggttattct tgttttgtaa cacgctatta
    22081 aaactgatat tgaagaagct tgaagataat agtaaaataa aaccctaaac ttatttaata
    22141 aatggaggat ttttcaacgt gaaaaaatta gttttagcca gtgcagcagc acttgtatta
    22201 gcaggagcaa ctgtaagtac aggaacagta agtgcgaata gttcaagata taattatacc
    22261 ggttggaatc aaggtgggta ctcatggaaa tatttgcgcc taagaaataa aaatccttat
    22321 tcacgtcgta cccttacaga agactattct gatcaaagaa agaatgaagc aaaagatagt
    22381 attaaagaat tgagtaagct tagtgataaa gagaaaaaga attttgctga tagaattgat
    22441 gctttgactg acacctatgc aatcagctct attctatcag aagctaaaaa taagaataat
    22501 gactatttag aatttgataa agaatatgag gctttattca attcaaataa gtataagtta
    22561 gaaatagaga aaataaagga tcgtgtgtac tttgatgaag gttactcagc tagacaaggg
    22621 attaatgact tgaaaagtct ggagaattaa acagtagaca gatttattat ttatcaaaat
    22681 aatccaactg aaagtctatg ttttaaggaa gcttattaag gtataattta taagaaaaat
    22741 ggttcagaat agtatttttg gaccattttt
//
LOCUS       DARYXZ010000037        22722 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYXZ010000037 DARYXZ010000000
VERSION     DARYXZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22722
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(72..2753)
                     /locus_tag="TV186_001350"
     CDS             complement(72..2753)
                     /locus_tag="TV186_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL1532738.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TV186_001351"
     CDS             complement(3101..3487)
                     /locus_tag="TV186_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL1532739.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TV186_001352"
     CDS             3568..4869
                     /locus_tag="TV186_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1532740.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TV186_001353"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TV186_001353"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL1532741.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TV186_001354"
     CDS             5903..7117
                     /locus_tag="TV186_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL1532742.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TV186_001355"
     CDS             7117..8352
                     /locus_tag="TV186_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1532743.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TV186_001356"
     CDS             complement(8561..9319)
                     /locus_tag="TV186_001356"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL1532744.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TV186_001357"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TV186_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL1532745.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            11732..14878
                     /locus_tag="TV186_001358"
     CDS             11732..14878
                     /locus_tag="TV186_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532746.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
     gene            complement(15172..16265)
                     /locus_tag="TV186_001359"
                     /pseudo
     CDS             complement(15172..16265)
                     /locus_tag="TV186_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(16249..16719)
                     /locus_tag="TV186_001360"
     CDS             complement(16249..16719)
                     /locus_tag="TV186_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1532747.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            complement(17032..17355)
                     /locus_tag="TV186_001361"
     CDS             complement(17032..17355)
                     /locus_tag="TV186_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532748.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            complement(17356..17748)
                     /locus_tag="TV186_001362"
     CDS             complement(17356..17748)
                     /locus_tag="TV186_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1532749.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            complement(18011..18424)
                     /locus_tag="TV186_001363"
     CDS             complement(18011..18424)
                     /locus_tag="TV186_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532750.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            complement(18417..18845)
                     /locus_tag="TV186_001364"
     CDS             complement(18417..18845)
                     /locus_tag="TV186_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532751.1"
                     /translation="MSEEQYLPVKESLGYRNLKIALMNVFSIDLDKFTIIEGEFENFG
                     FHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDT
                     EKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            complement(18842..19246)
                     /locus_tag="TV186_001365"
     CDS             complement(18842..19246)
                     /locus_tag="TV186_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532752.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
     gene            complement(19505..19927)
                     /locus_tag="TV186_001366"
     CDS             complement(19505..19927)
                     /locus_tag="TV186_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532753.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            complement(19909..20538)
                     /locus_tag="TV186_001367"
     CDS             complement(19909..20538)
                     /locus_tag="TV186_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532754.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            complement(20797..21120)
                     /locus_tag="TV186_001368"
     CDS             complement(20797..21120)
                     /locus_tag="TV186_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532755.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            complement(21121..21540)
                     /locus_tag="TV186_001369"
     CDS             complement(21121..21540)
                     /locus_tag="TV186_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1532756.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEIN"
     gene            complement(21976..22563)
                     /locus_tag="TV186_001370"
     CDS             complement(21976..22563)
                     /locus_tag="TV186_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532757.1"
                     /translation="MIDKIKNILFDVRLSANKIENEIIFYNGFPEDSVSLSFAGNKCI
                     IEEIHRDNRIRLMETTSEYHAILYCVAILDQIFNTSKNIKITREIKEYIQEGNIIAAE
                     QLLSEKLDPTLFSLGSVEKDKLTLVKENNAYSLIFNDVQILTDLSSLRAYIVLFNYTK
                     KLERAKELYARALHDLPDCKLEFNQFVEYYLIGRN"
BASE COUNT         6838 a         5012 c         4152 g         6720 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgaggacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaatct ttcatgtgtc tatcgtggtc gatgatcgca gagttagctt gttaatattt
    11341 tctatctttt ttattatatt ttgttaattt tataatctat ttaactattt taaaaattta
    11401 cttatttaaa tcacaaaaca ctgttataat aacgttttaa ggctatcaat gattaagaat
    11461 tttccaaacc tatttatcat ttctaggatt aaagaaaata tatattgaca tattctgatt
    11521 ttttaatatt atggaataag agagacaaaa tagtcaaaaa ggagggatag gatttttagc
    11581 accgtaacaa tatcatcacc acagcatcaa gagctaagga gggtaaatag tctttctatt
    11641 ttatagtatt tgcgagtata gttttaaggc tagctattct tttcccagag ttttgaatca
    11701 ctttatttta ttgtaaaagg actttataac gatgaaacta aagaaaataa tagcactagc
    11761 atgtgttgga atattaacat tacatcagct ctctccagca attgtttatg caactactga
    11821 tacttctgat ggaatagccg ctacagttaa tgcaggtgat acagctgctc cttctgccga
    11881 ggctaagcta tcacaactga tgactgatac ccaagcctta tttacagata actcctgcag
    11941 taagctggca agtggtgtca cacaagaaaa aatagatacc ttaaagcaaa aggcgactga
    12001 ctcaacagag cctgaaaaag agcaaatcct aggtctacta gataaggcag ctagcctatt
    12061 acagcagttt accctacaag ggttaggcaa tggtgtcttt gctcaacttt acttctatgc
    12121 tgatggcagc tacactgcaa gtttggtcac taaaaggggc cagcctcact cttatttctc
    12181 tactaattac gctacgataa ccattcttaa taacaagaag gaaaccgtct attcaaaaga
    12241 atacgccggc aatgtttctc aggtagcaca aacagaagag cttgagctaa aagaaggcta
    12301 ttacctcatc atcaataaac aggagcctaa ccgcttctac actaaccata atgacgctct
    12361 aaagcaaaac aataccaacc cttatactta tgtggtgaga gatgggcagc ttgagcgtat
    12421 tgatgatagt aatagaacgc tgcgcttcct tggcttaggc aatgcagagt atgcaacctt
    12481 aagggttgat tacaatgcct ctaccctaac cctcaaaacc aagcagacca agccacatgt
    12541 ttacttcagt ggatcttatg aaaagcttga ggtgctggat acagaaaatc aagtaatcta
    12601 cacaaaggac tttattggaa ctcaagtcct cgaagctaaa acagagacta ttccttttaa
    12661 agtaggctac aagatccgct tgacaggtag tgagcaccat accagagtga aattctacga
    12721 tgattatgcg gtagaagcgc cattaacact ctctaaaaat caagcaacct taaagcttct
    12781 tgaccactca ctagagctaa tgaggtctaa aacaggctca gagcttgagt ctgaggtact
    12841 gactctattt acagatgagt ctacaagtaa gctagcaagt ggtgtcacac aagaaaaaat
    12901 agatgctctt aggaaaaagg cgactgactc aacagagcct gaaaaagagc aaatcctaag
    12961 tttacttgat aaggcagcta gcctgctaca gcaatttact ctacaagggc taggaaatgg
    13021 tatatttgct cagctctact tctatgctga cggcagttac actgcaagct tagtcactaa
    13081 aaaaggacag cctcactctt acatcgctaa caattacgct accctaacca ttctcaatga
    13141 gaaaaaagaa accgtttatg ctaaggaata cgtgggtaat gtttcccaaa cagctaaaac
    13201 agaaagcctt actctcaagg aaggctatta cctagtcatc actaagcagg agcctaaccg
    13261 cttctacact aaccacaatg acgctctaaa gcaaaacaat accaaccctt acacttatgt
    13321 ggtgagaaac gggcagcttg agcgtattga tgatagtaat agaacgctgc gcttccttgg
    13381 cttaggcaat gcagaatacg caaccttaaa ggttgactac aatgcctcta ccttaactct
    13441 caaaaccaaa aaggctaagc cacatgttta cttcagtggg acttacgaaa agcttgaggt
    13501 cttagaccta aaagacaagg ttgtctacac acaagacttt attggaaacc aagctctaac
    13561 agccaaaaca gagactattc ccttcaaggt gggctacaag atccgcctaa ctggtagtga
    13621 gcaccatact agagtcaaag cctatgatga agaaaacaag gctgtttctc ttagcctccc
    13681 taaaaataag gcagagattc gaatcaccaa gggtggtttg gcttctgtat ttgcactaga
    13741 ggctaaagct actaatacac tcgtacaagc cgttgaaaaa agactaacca aggaaaaaat
    13801 cgaggacttc aagaagcaag acgacaagca taaagccttt attgattggt tgctcaaaga
    13861 taatgaagca atgcaattat atcttggtgc aggctatgcc cattctgcag cacagggtgg
    13921 catgtcatca taccaattca aaaacaccta taacctcacc aatgagctag aagcattgga
    13981 attgtggttt aagatttggg ataaatacga aacctcacat caaggtattc agctcaaaat
    14041 ggccattgcg gttgccttgg aatttaacaa gcctgtaggt gcttggtaca atgaaagccg
    14101 caagattgat ccacttgaaa gatttgcaac ctttgcagag gctgagcagg gcaatatcct
    14161 atttgaagat ttttacagct taactgttga gcaaatccga aatgtcgtca atgctaaaat
    14221 tactgatgag gacatgaaat ggttaagaca atacgttgaa accaataagc ctgctatgat
    14281 taaccgtaat gatattacta agggctattc actgatcagc tatgtcatga ccaacccaga
    14341 aacaggtgtg agcgtccaaa gctctggctt ttacggacca aatccaacca tcaaggaagt
    14401 catcaaatat ggtggtgtct gcggtgctat gtctaaatta agtagtgtgc tagcacaggc
    14461 ttatggtgta ccagcctttc ctattggaca accaggtcac tgtgcttata tctacttaaa
    14521 tgctgaccat acctatcagc tcggctatga tgtctcaggc tggacaggct gtggtaacta
    14581 caacacaaca cttccttatg tccaaattca taacgtctac tctcttaata tagacgctta
    14641 taatgcctca gaatatgaac gatataaggc tgaagcagct actgacaagg agactaagct
    14701 taatcattta gatgctgctc taaaggcaga gccattaaac tataaagcat ggaatgacaa
    14761 gctagcattg gtagcctcag accaaacagc atatcaaagc actctaaatg acatgaagtc
    14821 tgcattgaag gattatccag ttattatcaa taatttagaa aaagatacta aacagtaagc
    14881 taagcccttg ggcttaaaag aaggctagct aaaactatac ttacaaatac tataaaatat
    14941 aagagtctca gcttgaagga catgctcaat tgagagagct gcttcaagct tttttgattg
    15001 cagcaaagca aaaagcccca gaagcagtga tcaaacactg acctccaaga gccttttgac
    15061 gtcttttgac ctaagctgga gcttttttaa gcatcgattt acttaatcta atctctttta
    15121 ggctttttat cctttgcctg atgcgcttga ttagcagcac aagcttttta tttacttggt
    15181 tagctgatga tagggctgaa tggcaacaga ctgaccaata tttgaggcat aaatccaatc
    15241 agctgttttt aaggaggcaa actgctcagc cttgccggtt aaaataatgc cagcaaactt
    15301 agctgttttg acattgcgat tgttttttag aaataaggcc acatcctcct gctcacttaa
    15361 atgagatcca ttagcgccgc cataggtact attaatccaa tgattgtcag ctgcctcttg
    15421 tagatagtgc ctgaaggtat cataggaatt ttgcagagcc accgttggac tgactggctt
    15481 atcgtaagca gcattaagct tagacaaatc agcctcgctg tcctttttta ggatatcgtt
    15541 tattttttta tctaactgct tttgctcctt gtacgtcata ttagccttcc agtttggctt
    15601 aaagccatat aaattagcag ggaaaagccc tgaggtgtca tagctgcttt ctgtgccaat
    15661 ccagatccaa ttcagcttta gctggtctgg aaccagcttg actatgtccg ataataaata
    15721 aggcttatca aaggtaatgg ctacctcaat cgcctgtcct gacatgtcag caataaagtc
    15781 taggtcctgc gttggcttgt catagttgct ttctgtgatc ttggccttag tgttgaagaa
    15841 gcgaggcatt ttataatgtg tacctcttgt gtaggttgac cgtccatcat cacctgaaac
    15901 aaggtattca ttggtatagt ccatctctct ctgggtaaag gcaaggaata aggagctcta
    15961 tagggctcaa acggtaccga aatcccagca atatccttgg tccgctcaga atgaagctca
    16021 ccagtaaact gcgaattggc attgtaaaag aagctattaa catcaatatt gggataagca
    16081 atttgtatac gattgttgta ataagccatt aaatactgac cgttcatgct tgtcaatcga
    16141 tttaatccca tatagcccag tacaagagct actaaggcta agccagcact cagcactaca
    16201 tatttaaggg tcagcctcct tttatggcgc ttagcaatgg cttcaaaatc agttgaaatc
    16261 gtcataggta taacctgctt tctttagttt ttctttaagg catcgtcttc cccgcatcaa
    16321 gttgaccttg acgctgctaa ctgaccaatg gagcagagac gccatttcct tgactgatag
    16381 gtcctgaaag taataaaacg acaagaccca gcggtatttt tctggcaatt cattgactgc
    16441 tgtataaagc ggctcataat tggggtggtc aaattcaaca accctttctt gatgaaaaaa
    16501 atccctttgg agaatatcca agtaagcctt atcccgccta tatcggtcaa tgtattttct
    16561 aacagcaacc cgatacatcc aggcacgtat tttttcagga ggcagagcaa ggtcactctc
    16621 aagcattttt aacaaaacgt cttgactaat atcacgcgct agctccttag caacacctga
    16681 tctcactagg taggcaataa tttccttaga ataagccact agctctcttt cataagcatc
    16741 tagcctgata attctcccct cccttcttca cctatataac gaacgactgc ttcatttggt
    16801 tacaaaaaaa tccccaaatg gagattttta gctctatcat ttctgtagtg ggtaagtcca
    16861 ccatggagat tatagggctt ttttatatga caaaattcaa attaagtgca acacttttcc
    16921 ataaaagagt tcataagata gtttccagtc gggacatttc ctaggaccat tatttcattt
    16981 atcttcccac tctaattgac tacatgccat gtatattctc ctttacttgt attaattttt
    17041 tgaccacaaa ggagaatcgt aatttacagg catgccctct tccacatagt acctgttgat
    17101 ttggatatct aaccgaagtt tttcaagaaa tttttcttta gcctcttgaa atgtttcaaa
    17161 tgttaatttc ttattataac tagctctatc catagttgca tacacaacat ataagccttg
    17221 actattatca tattcaatga cagtttccca ttctcctggt ctctctttag aaaaaatgga
    17281 ataccttaga ctatcataac ctaattgatg gactgcttct aatagttctg ccttttgatg
    17341 atctaaattt ttcatctact ttatctcctt aattaaaccc aatttttcat accaacttac
    17401 agaagttcct aactttattt ggatacctcc accagagcca aagacaagat caatcattcc
    17461 tttttgtgga gttgctatgt ctaccagtga aaaatcaaat ctattcatta atagatttaa
    17521 ctcttttttt ctactatcag ataaattatg gtaacccttt tcaacatttt ccatattaat
    17581 atccttaaga accttatatt gatgataatt ttgatagtcc tctgggtatg gtaagcctcg
    17641 cttgttaaat ggtataacct tacggtcaac gattggactt gtgaatgttc ctccagattc
    17701 tccatatcta tcaagtaaat cacctgtttt taggaaagct ggagtcatga taggccttcc
    17761 ctttacatca agactaaagc cattatagtt tggccaatta atagaaccat cagccttaag
    17821 gtaatttcta tatcggacag gaattggtgt tccggtagct ttatcaatgt cattggacag
    17881 ataagcatat tttccatctg gcatggtgat tctttctgca aaataccttc cctttaactg
    17941 gtattctctt cgaaggtatt ggtaaatact gttcttcact catctatatg ccctccagaa
    18001 gtgattagaa ttattgttcc tcttcacatt tttgatccag ataatccttc aaaacacgca
    18061 taacatattc aacagatttc agatccagtc ctaagcacca tcttatattt tcacttacat
    18121 ttttatcaga aattaaataa gaaagtgata caattttttg aaatgactgc tccggatatt
    18181 taggattagg taaacttaca ctgaataaac caccttctcc agcttggaat tgaatattct
    18241 taccagtatc ataaattccc atcatcattt cacaattttt atatgtaaag acaaagttaa
    18301 aattctcatc ttctccttca tgtatagaaa tttcatcaag gttggctgaa aaaatagtcc
    18361 ataaagcctg tttaacgttc ttataaccta agctttcttt tattgataaa tattgctcac
    18421 tcatttttca ataaaacctt tgcttcgtct gaatctaaat aatcttttag aatggccaac
    18481 gctatttcga gacgatgctc gtatcttcca aaagcatagt caactgcttc tattttttcg
    18541 gtgtctgtta aaagactttc taaggttacc ctatcaagaa aggatctatc aggatacttt
    18601 ggattaggaa gtgaaatcat caattgtcct ccttctccat attcaaattg tctattctta
    18661 ccagttgatg taatccagat tatgatttct ttattgttat aatttaaatg aaaaccaaaa
    18721 ttttcaaatt ctccttcaat aattgtaaac ttatccaaat ctattgaaaa aacattcatt
    18781 aaagctattt ttaagttacg atatcctaag ctttccttta ctggtaaata ctgttcttca
    18841 ctcatttata tgccctccaa aacctttcaa atttttcaat attatatcca ttttctgcta
    18901 aaatctgaat ttctttagca taagacttcc cgataccact aacatctgcg attgattgag
    18961 cagtatatgg attagacgtt aatataaatg tttttctttt ctcaatttgt tttatcaaaa
    19021 attcacgatt aaccctttga gctagcttag aatccactct cgacatcgca ttccaaccat
    19081 cacttccggc atcaaagtaa gttaacttat tttgatgtgc aatttgttca tacgaagtaa
    19141 cgctgtttgc ttcgtaatat cccagcaaag ctgttttggt ttttgcattg tgggtggtca
    19201 gctcggttaa tttggccacg tcagcttctg tatagttctt actcatactt tctgcgtaag
    19261 ccacaatgcg agactcatca aaccgaacct ttgtgtctag taccttttca gaaagggtta
    19321 ttttcgctga tttcgtcact ttagctgcta tcggctcatt caagctgaac cttctggcgg
    19381 cgcttggaga cgcttggcat tggcttcaag gtgacgagct actccctgat aagctgtcgc
    19441 aggctaatta ttaagaacat gctttaaaat agcagagcta atctcggctc cgctatctta
    19501 aacattattt caaaggactg acataatcat ctggcagctt tcccttccaa tctatccact
    19561 gttgttcagc gattggcact aattttgata attcttcttc tgagaacaga gacacactag
    19621 tagggtctgc aatcagcgca gttggtgtgt caataacaaa ttttctatga ctttgcttct
    19681 tttcctcttc tgttggtggc caattaccat cttgtagctt tgaatgaaca tctccaagac
    19741 tacgttctcc actttccaac aattcaaata agtcatacgg taactcatat actactcgtt
    19801 gaacagcaat gccaccttct tcggcaacaa agtaatattt cccttgatgc ttccacaccc
    19861 tttgaccata gccctttacc tcctcatatt gactaacatc ttcccactct aattgactgc
    19921 gtgccatgtg tgatctcctt tctttgtact gataccttgc ataactccct ctggtatatt
    19981 ccccggataa gtacgacctc caggacgcca ccagctattt gccccttttt cattaccact
    20041 tggtattgaa acaccttttt gtgaaacaac ttctggtgaa acatctaagc gatagagggg
    20101 accatcttct aaataccctt catcaaagcc taagagtgtc tcataaagac ggttatttcc
    20161 ctttcctatc tcctggataa tatccgcgtc cttggtactt aaccaaaaac tattgcctaa
    20221 atcgtcacca actaaaccgt cttggtaatc tacattgggc ttaaatttct gaaatctagt
    20281 tgcaccgtta tcaaattgtt ttctatgaaa tccaatataa tctggactgt agactttctc
    20341 cacatttgga cgatcaccct tggatattgc caatatacta tctgatgttt ttcccggaag
    20401 atactctatc ttcggtgcct tctcagatat ttctagaatc cttactcgat ctgacggact
    20461 aagtccagcc tttgcgtatt tgtgccattg aatatagcgc tgactatcct caggactcat
    20521 gcctgcaagg gttgtcatga atttttctct tgctacataa ttcttaaacc ttgagctttc
    20581 tcttgccagt ctgctgttct caaggttctt caaaagctgc tggcggttgt gggtcggttt
    20641 cgtcacccta gttgctattg gctcattcaa gctgaacctt ctagcggcgc ttgaggcggc
    20701 aagtcctcct aggatattcc caactaatgt tgctctttgg gcgtcttgct cgctgcctcc
    20761 taaaagcttg gtgccatggc atacaataca tgaaactcat tcattccata gtggtgaggg
    20821 atattctgta ggttcaccta actgcttttt taaccgatta gattctataa ctaattctaa
    20881 ttttttaagc aattcatgct tggcatcatc aaatttacga tattccctgc tatgaccaat
    20941 gatatatgat cgctcatctc ttccttcaac atagaatttt ccattttttt gataaagatg
    21001 aaatgcccaa ggaagtcgct tttcttcatc aaataaaaca taatgtaaac tctcaaaacc
    21061 tcgattttta attgcttctt caatatcttt tttccaattc aatatatttg tattatccat
    21121 ctagttaatc tcctttaata aacccatttt cttgtaaata ccaacacctg tcggaaattt
    21181 aatctgaatt cctccacctt gcccaaatac tttggtaatc tcacccttct gaatattagc
    21241 taaatcatca aaggaaagat tccatttttt catttctaca gatatttgtt ttcttataat
    21301 ctcttcagat tgataatacg cattaacaat atttttcttc gtcaaatcca ttactaattc
    21361 gtacttataa tagtcttgat atccttctgg gtagggtaat ccacgtttat taaatggtaa
    21421 tgtcacccca ttttctatcg gactggtaaa tcgaccacta cttgatccat atcgatcaat
    21481 gatttgacct gctttgagag tgacctgctc cgttatagga ttacctaaat tatccaccat
    21541 aaagccatcg gcatttggcc atttaatatg gcctgcttcg tcaacaaaag ctctagagcg
    21601 aaccggaatt tgcttgcctt caaaatagtc agatgaaaga taacctatct ttccatttga
    21661 aatagtggtt ctttctgcaa aataccttcc ctttaaccgg tattctcttc gaagataatc
    21721 atcaaacctc gagctttctc ttgccagcct gctgttctca aggttcttca aaagctgccg
    21781 gcggctgtag gtcggtttcg tcaccctagc tgctattggc tcattcaagc tgaaccgtct
    21841 ggcgacgctt gaggcggcga atcctcctag gatattgcct actaatgtag ctcgctgagc
    21901 atcttgttcg ctgcctcctg ccatgactgg gcatctgaac tcaaaatgcc atatggtatt
    21961 tcaatagttc ttttattaat tccttcctat caaataatat tctacaaact gattaaattc
    22021 taacttacaa tcaggcaagt catgtagtgc tctagcatat aattcttttg ctctctcaag
    22081 ttttttagtg taattaaata aaacaatgta agcacgtaat gaacttaaat cagttagaat
    22141 ttgcacatca ttaaatatta aactataggc attattttct tttacaaggg ttaatttatc
    22201 tttttccaca gaccctaatg aaaaaagagt aggatccaat ttttctgaga gcaactgctc
    22261 agctgctata atatttcctt cctgtatata ctctttgatt tctcttgtaa tcttgatatt
    22321 tttactagta ttaaagatct ggtccaaaat tgcaacacaa tataaaatag catgatattc
    22381 tgaagttgtt tccattaacc tgattctatt atctctatga atttcttcaa tgatacattt
    22441 attacccgca aatgataaag atacactatc ttcaggaaag ccattataaa atattatttc
    22501 attttctatt ttatttgcgc tcagcctaac atcaaaaaga atgtttttta ttttatcaat
    22561 caattctaat ttctcctttc ttcaccaaat cagttatgtc atctaaaaaa ccatatccat
    22621 tagctcttga atactatatt tatcaactcc attaggttta tacttcacaa attgatctga
    22681 aacctcacca gcatatactc aaataaacat agtatcctct ga
//
LOCUS       DARYXZ010000038        20895 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYXZ010000038 DARYXZ010000000
VERSION     DARYXZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20895
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            126..1541
                     /locus_tag="TV186_001371"
     CDS             126..1541
                     /locus_tag="TV186_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1532758.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
     gene            1743..5494
                     /locus_tag="TV186_001372"
                     /pseudo
     CDS             1743..5494
                     /locus_tag="TV186_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            5723..6628
                     /locus_tag="TV186_001373"
     CDS             5723..6628
                     /locus_tag="TV186_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL1532759.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            6612..7496
                     /gene="isdE"
                     /locus_tag="TV186_001374"
     CDS             6612..7496
                     /gene="isdE"
                     /locus_tag="TV186_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL1532760.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            7498..8520
                     /locus_tag="TV186_001375"
     CDS             7498..8520
                     /locus_tag="TV186_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1532761.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            8517..9299
                     /locus_tag="TV186_001376"
     CDS             8517..9299
                     /locus_tag="TV186_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532762.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            9345..11108
                     /locus_tag="TV186_001377"
     CDS             9345..11108
                     /locus_tag="TV186_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL1532763.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            11101..12783
                     /locus_tag="TV186_001378"
     CDS             11101..12783
                     /locus_tag="TV186_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532764.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            12764..13357
                     /locus_tag="TV186_001379"
     CDS             12764..13357
                     /locus_tag="TV186_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1532765.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            13354..14034
                     /locus_tag="TV186_001380"
     CDS             13354..14034
                     /locus_tag="TV186_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1532766.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            13971..15425
                     /locus_tag="TV186_001381"
     CDS             13971..15425
                     /locus_tag="TV186_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532767.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            15789..17804
                     /gene="recG"
                     /locus_tag="TV186_001382"
     CDS             15789..17804
                     /gene="recG"
                     /locus_tag="TV186_001382"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1532768.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(17924..18889)
                     /locus_tag="TV186_001383"
     CDS             complement(17924..18889)
                     /locus_tag="TV186_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL1532769.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            18961..20349
                     /locus_tag="TV186_001384"
     CDS             18961..20349
                     /locus_tag="TV186_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1532770.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            complement(20635..>20895)
                     /locus_tag="TV186_001385"
     CDS             complement(20635..>20895)
                     /locus_tag="TV186_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1532771.1"
                     /translation="AKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIPDKEEVD
                     LIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
BASE COUNT         5598 a         4151 c         5093 g         6053 t
ORIGIN      
        1 aataagaaaa ggcccttacc tttatccgag tattaaggca ttaatacaaa aaatcttgca
       61 ttttattttg cttcaatgtt ataatgtagg ttagaataga gcagaaagaa gtgattgaat
      121 actaaatgag aaaaaataaa ttattaagaa tgataatgct gatgactctt ctggtacctc
      181 atttagagac cgcaagagta ttggcagagg atacaggagc tgaagccagc caggttccag
      241 ctactgctaa tgaggctgca atcgcccaga ctggtgagtc cacttcgaca gcagctgcta
      301 cctcagctac tgacaactcc tcatcaacca ctgagactac tcccaacagt ggagaacctg
      361 gagcaacggg gtcatcaagc aatacagcta gctctggatc agcttctggt tctactggac
      421 agtcgacacc tactagtcca gcagctagcc ctcagccagc ccctgaagtt gctacacagg
      481 catctcagcc ggcactgaat attgttcctg ctgctcctac agttgatttg tccttgactc
      541 tggccctgcc ttctgtaaat acctatgctg cttatgtgac gcattggagt ggtcagagtg
      601 cttataccca taacctcttg tctaggcgct atgggatcaa ggcagagcag cttgatagct
      661 ttttaaagtc taccaagatc aagtatgatg agaagcgaat taacggtgct gccttgctgc
      721 aatgggaaaa aaagagtggg ctagatgtgc gggcgattgt agccattgca atgacagaaa
      781 gtgagctagg aaccaaggga aatgcaacct tactaggctc taacatgttt ggctatgcgc
      841 tttttgacct tgattcgaaa aagccaaatc agtttaatga tgagcttgct attgttaagc
      901 tgacacagga gacgattatc aaaaatagca accttaattt tgagcagcag gatcaaaagg
      961 ctgataaatt tgccaaaaag cagttgaact ttgctagtga tggtggtctt tacttcacag
     1021 ataccaatgg cattggcaag cgtcgcgctg agatcatgga aaaattagat gcttggattg
     1081 atcagcatgg aggcacgcca gagattccgg ctgagctgaa aattcaatcc tcttcaagct
     1141 ttgctgttgt tcctacaggc tacaagctgt ctaagagcta tgatatttta agctatcagg
     1201 cgtcaagcta tgcttgggga caatgtacct ggtatgttta taatcgcgct aaggagctag
     1261 gctatcagtt tgattccttt atgggaaatg gtggtgactg gagatttaag tctggctaca
     1321 gtatttctaa ggagccaaag gtaggctatg cggtttcctt tgctccaggt caagcgggtg
     1381 ctgacggtct ttatgggcac gtctctattg ttgaggatgt cagaaaggac ggctccatcc
     1441 tgatttcaga gtcaaattgt cttggcttag gtcagatttc ataccgcacc tttactgctg
     1501 agcaggccaa ccaattgact tatgttgttg gaaaatcata agtaatcttc ttgctttaaa
     1561 ggcgagaagt acagaatttt tgtaagaaaa aatccagctc tgttgcaggg ctgttttttt
     1621 ctttgcttta ttgtgaaaaa aatctcaaat tcaatcttga caaaggcttg acaacataat
     1681 aaattaagtg agattaataa aataattaaa tggctaataa catttttaga aggttcgaaa
     1741 taatgaaaag tatcaataag tgcgccattc ttgctttatc aacgctggct cttgcccagt
     1801 ctgcccagac ggttcgctca gaggctactc aagtctcttc aagtcttgtg acgactgtca
     1861 agcttaagga taatatttta ttgttcgagg agatcggtcc ctatgcggac aagtcagagg
     1921 ggaagctcta ttataaaaat atcgagaaaa ttctcattga tggtaaagag tatgacaaaa
     1981 agctggaggg tgactatagc tatgacatca attaccaagg aatcaaggta aacgctaaga
     2041 acatcacaga aggacagcat cagctgcgca tcgtcaataa gactaacgga ggcattcttg
     2101 tggtctttga caagaaagga aatgatgtta cctttgtttc tgccaagcct tcagatgata
     2161 ctactgcttc accgcagcaa gctgctgcta agacagaaaa gcctgctaag gtaactagcc
     2221 atgatggctt agcgacccta tcatttatca ccaaactaga gacaacagaa ggagagcttc
     2281 tttttccgga aattgatcgc tattccagca ccaagcaaat taaggaatta gctcatcaaa
     2341 tcacaaagat caaggtcaat gaccaggact ataaggattt ggtctatgat tcagtaaagg
     2401 acaagcctgg ctatgtgtct gacctgaagg ggcttcatct tgggacgaca gctttcaagg
     2461 agggagaaaa caaggttgtc atttcctcac aaagctttga agatgtcatc attacagtga
     2521 aaaagtcagg ggagcaatac acctttgttt ctgctaagca aaagcagaga caaggatccc
     2581 agcaggaagc accgcaggga cttgatttta ctaagctgga aagcgcgatc aaggaagctg
     2641 agcgtatcat tgctagcgag gccaataaag aacaggtcaa ggacttgtct agcaagcttc
     2701 aggtgatcaa ggagtcctat cgtcagattg acaatgaaaa attgctcaag gagacctatg
     2761 agcttttgat ggatagtatc aagtcctatc agggaactga tctggctgtt acggatctaa
     2821 aggcaggaac ctatacctta acctttaagg ccaataagga aaatacagag gaagcctcaa
     2881 tgctgcaggg agcatttgat aagaaggcca agctggtcgt caaagaagat ggcaagatgg
     2941 agatttcatt gctcaataca gctctagggc aatttttgat tgacttttcc attgagagta
     3001 aagggcagta tccaacctct gtccgcactc aggttggtga acgcgatatt aacaataact
     3061 acattagagt gaatttaccc taccgattga ggagctggac aagcttcaca agggtgctgt
     3121 gctagtatca gctatgggtg gtcaggaaag cgacctacat cactatgaca aatacaccaa
     3181 gttggacatg acctttagcg ctacagcaag taagggctgg acaggctatc aggctgagat
     3241 tgacgacaag gaaaaagggg tcggctctga gcgtcttgaa aaggttttgg ttaagcttgg
     3301 taaggacctt aacggtgatg gcaaaatgtc acctgaggaa attgcgaaga ttgaaggtga
     3361 gctgcgccta gaccactatg atttgacaga tatttcactc ttaaagcatg ctaagcatat
     3421 tactgagctg cacttagagg gcaatcagat tgcaagcatt ccaaaggaaa ccttcagtca
     3481 aatgaccaat ctaaggttct taaatcttcg cagcaatgtg attacaaccc tagataagga
     3541 tacctttgct cataacagcc agctaaaaga gctctatctc tcaagcaact atatgccaaa
     3601 tctggaggaa ggactattta gaaatcttgg tcagctggat cagctagatc tgtcaaaaaa
     3661 tagaatcagc gtgattcgag atggtgtctt taatggtcta tctcgcttga cctccttggc
     3721 cttggctgaa aatatcatta ctgaattttc agaaaatgct ctagcttcac ttgataatct
     3781 aaacttcttt gatgtttctg aaaaccagtt gggcagcctg ccaagctcct tgagtaagct
     3841 aactaagctt tcttatatcg ttgccaatcg aaaccaggtt ttagatattg ctaatattga
     3901 ctttagtcat atgccaaact tattaaccgt tgacttggca tcaaatgagc taactaaaat
     3961 cccacaggga gccttcaagg ctaataagca gctatcaaag cttaatgtct ataataacct
     4021 tttaacgaat attagcgaag ctgattttgc agatctaaag gcattggatc ttgatcttaa
     4081 gtttaactgc ctaagtggcg ttagtgataa gcttagacag atcatgggaa caaataagct
     4141 aaacccacaa aagcaatttg ctaatctatc tgcgacttta aatcatcaag cgatgaccta
     4201 tcaccaaggg tttagcctgc ttgatttgta ttattgggag cagcagacac tctcaagcac
     4261 cgaagcagaa attagctctg ttgaggatta caataaacgc cttaaggcaa gctcgtcaga
     4321 catcattgcc ttattaaatg agcgttatgc tgactgggat attgtggtgc aattgcagaa
     4381 aaaaacatca accggtcaat atgtcaccgt tgatgagaga cgcttgaata acgatccaca
     4441 agatgagctt caaggctcct ttgacctaaa gggagcaggt gtttatcgtg ttcgtaaggc
     4501 tcttatcacc aaggaatttg ctaagaagcg tgagcatatt tatctgacct ctaatgatgt
     4561 tgaggtcaag gaggatcagc ttgcaggtag tgaccagtct aagggcttgg atattaataa
     4621 gcttgaagat ggtgtctact acatcaaggc aagcatgctt aaaaatgatt tgcagtcaga
     4681 atcaatgtct catcaggcta ttgaccaccg cgtcaaattg attgtgaata agggtgtcta
     4741 tagcctagag gtgaccttta agggcatgaa gatcggtaac ctgacagggt atctcggaga
     4801 gttgagctac tttgttgatg gctaccaaag ggatttgact ggcagaccgg ttggtaagac
     4861 agaaaaagca gaggttgtgt cctactttac agatgtcaca ggcaagcccc tgtcagacgc
     4921 ttatggcagc aattacccac aggtgttgag atttaggctg attgatcagg ctaaaaagga
     4981 tggcttggta cctcttcgcg tctttgtgcc aattatggac gctatctcta agggaacagg
     5041 cttccagaca gtctttatga agttggatct tcaaagcctg acaaaggata aggcacaatt
     5101 gccacactca gaggacaatc agggacatgg taccataggt gagctcttgc agcctcacac
     5161 aggtatcatt ggtggtcata caagtcctgc tattcctaat ttgaccaatc ttttgactaa
     5221 gaagtcagct gctccaagca gtaatgccaa ggaggacgct aagaccggta cagataagct
     5281 taagagcctg atttcttcac ataaggcgtc taaggctggt acaggcaagg cctctaagca
     5341 ggctgctaag actagagcca aagctaaatc taaggctgct aaacatagtc aggagcagat
     5401 gaaagctgat catcgcggcc atatcattat cggtctagca agctttattg tcatagcagt
     5461 tggtctcatt cttggtagga aaaaattatt ttaagtcagt agagagtctg tttgatgcac
     5521 taagagcttg gtttaatcgc ttgtagtcat caaggcttat caacgatacg taaaggcatg
     5581 cctgtttcta atgatttctt aagcttaccc ttggtaagtg aggaatgggt atgcttttcg
     5641 tatttgaggt gttataatag tcaaataaga gtaggtcttg gcctgcgtct aaatctatgc
     5701 cttatttgat tgtcgtaagg aaatgaagat cattaatgag gaacatatga taaagagatt
     5761 attcaaaaaa ttaatgggtg gcttggtggt attgctggtt tgcctagcag ctataggagg
     5821 taaggcctat gctgataagg gtgagcttta ttcctgtgtg attaggcgag attatcgtca
     5881 cccggtttca gggcaaattg aagatagcgg tggtgagcac gcttttgaga ttggccaagg
     5941 tatggtggaa ggaacagttt atagcaatgg tatgctagag gtaacctcgg ctggggattt
     6001 gtatctgacc tttcgcatga gtctagctga tttttcaggt aactaccaat tttgggttca
     6061 gccgggtggt acaggggctt ttcaggcggc agcctacagt gtcaccaagg ttggcactga
     6121 taccaatggc acaacaaagg atattgcgat tgctttgcct gatgtcaata cggttgttag
     6181 aggcagcatg tacgtagagc ctatgggcag agaggttgtc ttttacctgt caccatctga
     6241 gctacaagaa ggctacagtg gagatatggt agctagcttt gcagcaggag aagccaagac
     6301 ggatcatgcg gtgacagctc ctgcaaaggc agatgagaag aaagctccta gtaaaccgga
     6361 ctcaaaagac gccaagtcag ctcctaatcc ctcagcaagg ccagttggtc aatcaagcag
     6421 tcccaaaaaa cagtcaaatc cctctaagaa gggtcaggca gttggtttga gcacttcgct
     6481 agataaaagt aagcaagagt cgtcccaaaa gccagtaaat aatccattgc cagttctggt
     6541 ttactatgta ccaacagctc ttttgttgtc aggagccttg gtcttgttta taaagaaaaa
     6601 gagaaaaaac aatgaagaaa gtcattaagc ttattggatt agctgttttg tccttggtgc
     6661 tatctgcttg tgtggatcag caccctaggg cagagaaaaa ggctgataag gagagaattg
     6721 ttgccacctc tgtggctgtt gttgatattt gtgatcggct aagcctagat ttggttgggg
     6781 tctgtgacag taagctatac caattgccaa agcgttacga tgctgtcaaa aggatcggtc
     6841 tgccgatgaa tcctgatatg gaggttattg cttctctaaa gccaacgtgg atactcagtc
     6901 ccaattctct gcaaaatgat ttagagccta aataccagca attggatacg gaatatggct
     6961 ttttgaattt aactagcctt gaaggcatgt accagtcgat tgatgatttg ggggacttgt
     7021 ttgatcgcaa aaaggaagct aagcgcttgc gggctgatta tgaggagttt taccgggcct
     7081 ttaagaaaaa gcataaaggg caaaaaaagc ctagggttct tattttgatg gggcttcctg
     7141 gcagctatct gattgctaca aataaatcct atgttggtaa tctgcttgag ctggctggtg
     7201 gtgagaatgt ttatcactct gaggacaagg aatttttgtc tgccaatcca gaagacatgc
     7261 ttcagcagca gcctgagctg attttgcgta ctgcccacgc cattccagac aaggttaagg
     7321 acatgtttga taaggaattt gctgaaaatg atatttggaa gcattttgaa gctgtcaagt
     7381 ctcagcaggt ttatgattta gacaataccc tttttggcat gagtgctaag tttaactaca
     7441 aagaggcttt gaaccatctg tcacaaatct tttatggagc aaaggaagtc aagtaagatg
     7501 cagcaaggta gtcaatattc tgatcaagtc acagcagcaa gaaaaaggac cactagactg
     7561 gtctatatgg ttctattgct catgctgctg tttggtttaa tgctatatgc ggtctctgtt
     7621 gggggcttat ctgtttctta tcagaggatc tttaatggct tatttgtagc atatgattca
     7681 gaggtagccc ttatttacga tttacgcttt ccaaggattg tgattgcttt attggctggg
     7741 gcggggatag caacatctgg ggtcttgttt caggcgattt taaaaaatcc tatttcagat
     7801 ccggcgatta ttggggtttg cagtggggct agctttatgg tcttgttatc tagcctgctt
     7861 ttgccgcagc tcttgtttta tggtcctttg ttatcatttg tgggaggctg tgtttctttt
     7921 ttgatgattt ataccttgtc ctggaagaag ggcttgcagc cgatacgcat cattttgaca
     7981 ggaatagcta tcaacgcctt gtttttaggc ttgtctcgtg cgattactga tttttcaaaa
     8041 accagcaatc cctttgtcaa tgcgctgttg tcaggaaata ttagtcaaaa aacctgggca
     8101 gatgttggtg tgctgtggcc ttatacagtg cttggcctgc tgcttgcgat aggcctagca
     8161 aggcagtgtg atctactgct gctaaacgat ggcttgattc gtaatttagg cattgatagt
     8221 aattacctgc gcttaggaat ctcgttggtt gcggtcttac tagctgctgt ttccacctcg
     8281 attgtgggtg tggtgtcatt tttaggcctg attgtgccgc atattggccg ccttttagtt
     8341 ggcagtaagc atagctatct cattcctttt tctgccctgc ttggcgcctt tgtctttttg
     8401 ctggcagata ccttaggaag gcagttgtgt tatcccttgg agattagccc agctgttatc
     8461 atgagcattg tcgggggacc ttattttatt tatctgttaa ggaggtctga cgtgatatga
     8521 gtcatgagca aggcttgatt cgtgtagagg atttgtcctt tacttatcgt gataggccta
     8581 ttttagatag gctgagcttt accattccaa aaggcaagat aacgacaatc atgggggcaa
     8641 acggctgtgg caaatcaacc ctactaggtc tgctgactaa aaatatcccc gttaagtctg
     8701 ggcaaatttt cttagaggga caagctatta gctctattag tcttaagcag tttgcccaaa
     8761 aagtagccgt tgtgcatcag gataatcagg cggtagcaga tcttctggtg ggtgatttgg
     8821 tggctgtggc aagccaagcc catcggcgtt tttttaaggg atcaagtcaa gaggacgatg
     8881 acattgttgc ttgggcctta gaggtgacta atctaaggga attggccttt agggaaatgc
     8941 aggagctatc tggtggtgaa aagcaaaggg tctggattgc tatggcgctt gcccaaaaaa
     9001 caggtgtctt agtgcttgat gagccaacca cttatcttga tattaagtac cagctggaca
     9061 ttttagccct catcaaaaaa atcaatcagg agctaggaat gaccattatc atggtgttac
     9121 atgatattaa tcaggccttg gctgtttcgg attgtgtgct tgggctgcaa aaaggtgcca
     9181 tctatgccca aggcagtcca caggaggttc ttgatcaggc ttttgtggag gcggtttttg
     9241 gggtgagctt gccctttatt gaaaagcagg ataggcgatt tgttcttacc actttatgag
     9301 acaaataaaa aatgaatgat agataggaat aaggcgacga ttatatgaac gatacaactg
     9361 aaaaaatatc acgcgcaaag aaaaaaatgc ttttaaggcg tttaaaggag cgtattgctc
     9421 ctaagcgttt tttgctttat gtgtcggcct ttttatcttg gctgcaattt ttgatgcgtt
     9481 taatgagctt ttacttaatt gctaagcaat tcacagcctt tttagcaggt caagccctgc
     9541 aattgacaag gctgcttgtt atccttttga ttttaaatgc tgttggcttt ggcttggcga
     9601 tgattgcaaa gcagctgcag ggcctagctt cgcaatttgc gcgtgactcg ctcaagcaat
     9661 ccttttttga tgcctttatt gctatggacg ggcaatttga tcagcagtca acagaggctg
     9721 atgtgttaac ggttgcctca caagggattg atagcttgga tacctattat tcctattacc
     9781 tatcgcttgc aatgctaaca gcttttaatt gcacaacggt cttactgctt gtttttttga
     9841 tctatcctat agggggcttg gtctttatct tgtctttgcc cttgattccc atatccattg
     9901 ttgctatgca aaaacgctct aaaaggatca tgaaccatta ctggtcaacc tatatggacg
     9961 ttggcaatct atttatggac gatctcaagg ggctaaatac cctttattcc tatcaggcag
    10021 atgaaaggta tgaggaaagc tttgtcaata aggcagaggc ctttcgtaag gctaccatgc
    10081 agctcttggg ctttcagctg caagcggttg gctatatgga cgctgtcatg tatcttggca
    10141 ttggcttatc tggcttttta gcggttcagg ctctgtcagc tggtggtata tccttttttg
    10201 actttctctt ttttatcctg attgcaacgg aattttttgc ccctattagg gagcagggct
    10261 atggcatgca cctagtcatg atgaatacta aaatggcaga tcaaatcttt ggctttttag
    10321 atagcgttga ggctgttgac caagacaagg gagttgcctt accggccttt gatcgtattg
    10381 atattcaaga tttgtccttt tcacatgggg aaaaggcttt gctaagagac atcacgatga
    10441 ctatcaaaaa gggtgagcta acagctgttg caggtgtttc aggacagggt aagactagtc
    10501 ttgcacagct cctgttgaag cgctatcagg cagatagcgg tcagatattc cttggtgatg
    10561 tgacgattga tctggcttct aaacaggcca tcaatcagga aatactctac gtttctgacc
    10621 agtcaacgct gcttaatatg agtatttatg agaaccttgc tatggcagct cagctgacta
    10681 gaaaggagct gcttagctgg attgatgagc atggcatttt gagctttatt tactggctac
    10741 ctgatgggat tgataccatt gtaggtgaga atggctgtca cttatctgca gggcaaagac
    10801 agcaggtgat ttgtgctagg gccttattga gccagcgttc ctgttatatt tttgatgagg
    10861 ctacctcaag tcttgatgct gagaatgaag ctgctattca cagactgctt cagcaattgg
    10921 ctaaacaggc cattgtaatt gtcatcactc ataagatgaa atatttgaag caggctgatc
    10981 aggtgctctt tttaagccct gagcagtctg ctagcttggc tagcccaaga gagctttacc
    11041 gccatcattt ggcctatcgt caattagttg atacacaagt agaattggag gcaaatcttt
    11101 atggttaaga gtgattacag cacctaccgg ctagttttac gattgcttgc tatgatgaag
    11161 catttgctgg cttggatagc tctggcggtg atgtttgcag tgctgggctt tgtgcttacc
    11221 gttggcattc ctaccagctt agcctatctg ggcttagagg tgatggctgg tcatgctatt
    11281 acctttaaat ggctttatct atttgttgct atggcactgc taagggggct tgttcgttat
    11341 ggagagcatt attttgggca ttttgttgcc tttcatagcc tggcagcctt tcgcaggatt
    11401 gtctttaaaa agctaagagc actctcgccg gcacgcttag acagtcagga cagcgggcac
    11461 ctgttaaaga tgattggcga ggatattgag gccttggagg tcttttttgc ccacacgctt
    11521 gcccctattt gtacggcgtt tatttcagct agcttgatgg cctattacct ttggcaggtt
    11581 agctggaagt tagccttggg ggctattgtg acctatgtgc ttttggctgt tattattcca
    11641 gtgtattttt caaacgtcct tcaatcactg ctcaaaaagc aaaatgaagg gcgcagggct
    11701 tatgtgtcaa gctttttaga gagtctcaga tctgttaagg atttgctgca atttcaaagc
    11761 attgagaagc gctttaagct cttatccaat cagagcaagc atgttaatgc gcttgatcgt
    11821 caggtggcac aggctcaatt tttacaaatg gcgataacct ttttggctct tggcttgtct
    11881 attttgacct ttgcttatgt tactcttttt gagctgagtc agcagacggt gacgtttgct
    11941 ggtgggttgc tggcttttgt tgcctttaca gcctcctttg cacccttttt agaattgggg
    12001 cgtttgccgc ttggcttcaa gcgtgccatg aatgctgcta ggaatgtctt tcagctttta
    12061 gatgaagaag cgttagtaga taagggagat cagcgtattt cctcggtaac aaggattgct
    12121 gttgaggatc tgacctttgc ttatcccaag catcaggaga ctatttacca ccacttatcc
    12181 gtcgcttttg aaaagaaagg cattatcggt attcagggag agtcaggctc tgggaagtca
    12241 actctgatga agatcattat gaaatggtac aattggcaag ctggtcatat tttcctgagt
    12301 gaggttgaca gtcaaacgct aaatgctgct tccctacagg ctaactttgc ctatgtccca
    12361 cagaatgcgc agctatttca gcaaacactt cgtgacaata tcacacttgg tcgtaaggac
    12421 atttcagatg atgatatcat ggaacttgct gaggcctgtg gcatgaagga gcgtatccta
    12481 gcctgtgatg aggggctaga taccctagtg agaggatcag cagacttttc agctggtgaa
    12541 gcccagcgct tggaattgat gcgggctcta ttgaagcggg cggattgcta tatttttgat
    12601 gagccaacat caaacttaga ttcgctgaat gaagccatct ttattgattt gattaaaaag
    12661 cattgccggg gaatggtctt tttgatttca catcggccat ccaccttggc ctgtgcagac
    12721 cagctatttt gtgtgagaaa tggttttttg aaggaggtaa acaatgaaag ggttaaccat
    12781 taaagatatc atgacaacag gcgcctttgc cgccctctat ttcgtttgtg tggggctagg
    12841 agccatgctg agcattctgt ttgatcgctc aggcaatatg ctctatgcgc cagcctttgc
    12901 ggccttgctt ggcgggccag tttatatgct attaatcgct aagctgcaga cctttggacc
    12961 gataagccta gtaggaatta ttatgggaag ctttttcttt ttgacaggtc atttttttgc
    13021 ttcaatgcta ccagctattc tttttggctg tttggcagat ggcatagccc ttttaggaaa
    13081 atatcaatct agactagtga atctcttgtc ttatcttgtt tttgcctttg ttaacagtgg
    13141 tcctattatt ttaatgtggc tgttgaagga cgcctatatc cagagtcttt tagcgcgtgg
    13201 taaggacatg gcatatgtta accgtatcat gtatgacttt accgttgcaa atgtcagctg
    13261 gtttgttggt gttgtccttc tttgtgcctt agtaggtggc ctttttggtc aatacctgct
    13321 gaaaaagcat tttgctaagt caggaatgct tttatgaggc ttgatgttcg cacaaaattg
    13381 ctcctgttaa ttctagccaa tgcctgcttc ttttttcgga ttgatggctg gctggggacg
    13441 atgattatag gtgttttgct tggcattttg ttttggcttg gtcaagggcg tctggcaatc
    13501 ggtatgacac tgctctatgc cttactgctt gctttgtctg tattgccgct tcatgtgctg
    13561 ccagcctatc tgtttaggct gctgagcttt gcagctgttg ctggtcaatt gctttaccca
    13621 tctgtgcttg ctgctttgat ttttgtcaag acaacgactg cctacgagct tgtgcatggg
    13681 ctgcgaaaat ggcatgtgcc agaggtttgt ctgttgactc ttgctgtcat gctgcgtttt
    13741 ttacctaaga tcaggcaaga aggaaagatt attcggcaat ctctgaaaat caggggcatt
    13801 ttcttggaca gctgggctat tgtcagacag ccaaggcggt atatggagta tctcttggta
    13861 ccgctgttga tgtcattgct gagaagtagt caggacttaa ccattgctag cctaacaaaa
    13921 gggctagcaa tcaaaaaggg agcaagtgag tgcttcgtat cacatctatc atggaaggat
    13981 tggggggtac agatttggat atttgtgacg atagcctaca tggttctcca gtgatcaagg
    14041 caaagcagct gcagttttcc tataccaatc gtaggcagac tgcctgtgag ctcagggatt
    14101 gtcagataga ggcaggtcaa tttatcgtgc tttgtggtca gtcaggctca ggcaagtcaa
    14161 cctttcttaa gctgctcaat ggcttgattc cagactattt ttcaggacaa ttacaaggaa
    14221 gtctgaaagt actgtctcat caggctggtc aggctagtgt tgaagtgctg tcaaggcagg
    14281 tttcctctgt ctttcaaaac ccagccagcc aatttttcta tcgtgaggtc aagcatgagc
    14341 ttgtttttcc ttgtgaaaat caaggcttag agccagctct tatccttgag aggctggata
    14401 ccttggcagc tgattttgac atcaaggact tactagaagc agatatgctt aagctatctg
    14461 gtggtcaaaa gcagcgggtg gctattgcag cagctatcat gcaagggaca gctatcatgg
    14521 tttttgatga gccaacagcc aatttggacc atgctagtgt agcagcggtc aaggcttatt
    14581 taaagcagct taaggctgct ggcaaaacca ttattgtcgc tgagcaccgc ttgcattatt
    14641 tgctggattt ggcagaccat ttttactatt tttcagctgg taggctagag cgcgtattaa
    14701 gccccaagga tctgctagct ttgccagatc aggaacgtga ggagctagga ctaagacgat
    14761 gtgagttgac tgctgtgact aaggctttgc gggcaaaaac tgtttttgag cattatgatc
    14821 cagagcatgc cttgcaaatc aagcagctag aggtcaaggc aggcagcagg gttttgtatc
    14881 acctcaatca gctcagcttt ggtgcagggc aaatcactgg cattaccgga gctaacggtt
    14941 tgggaaaatc gcagttggct ttatatctgg caggtatttt tgaagcaaaa gaggccaaga
    15001 tcagctatct gggtgtcacc ctgcctgcta aggacaggct ttcaatcaca agcctagtgt
    15061 tgcaggacgt tgggctacag ctattttcgg agacggtaga aaaggagctt aatctaggtc
    15121 atcatagaca tcaggctact gatgatttgg tgaataggct tgggctttct cagcttctag
    15181 acaagcaccc tgccagccta tcaggtggtg agcagcaaag ggtgatgatt gctgccagcc
    15241 tcttgtctga caaggagatt gtcattcttg atgagccaag cagtggctta gatctgctgc
    15301 aaatgcaggc tctggttagt cttttaaagg agctaaagca gcaaaaaaag gtagtgattg
    15361 tcatctctca tgacgaggaa ttactggatc aagcctgtga tagtatctat cagttgagca
    15421 ggtaaaggcc tagccttgct caagcggtct ggtgctgtat tggtgatggc tttatcgctc
    15481 cttggagcag caggtgttcc tgcttgatct gataaccact agctgcgatt gaccaatcac
    15541 aagccgccaa ctcttgacaa gctagcagta gctatcacaa ttctagggca tatcttggcc
    15601 tagcaagcag tgctgtattg tttatatgcc actcttcatc ttttagttag gccgtcctag
    15661 cggccgcact aagggtgtgt taggatcggc taatacctca aggcatctac agtaagaaaa
    15721 cgagcctctt cctttttgga gaggctcttg atttttgata taataatgaa aaagaaagcg
    15781 aggttgagat gctgttaaag agttcgattg ctaatttgaa gggtcttggt ccaaagtcag
    15841 ctgagaaatt tcaaaaatta ggcatttatc agatcaagga cttgctactc tattatcctt
    15901 ttcgctatga ggattttaaa agcaagtcag ccttagagct tttagatggt gaaaaggctg
    15961 tccttacagg tagagttgtg actccaccaa gcgttcaata ctatgggttc aagcgtaatc
    16021 gcctgagctt taaattgaag cagggggagc ttgtgattag tgtcagcttt ttcaatcagc
    16081 cttatctgct tgagaaaatc gtcttggatc aggaagtggc tatctttggt aggtgggatc
    16141 aaaaaaaagc agccttgaca ggtatgaaat tgctcatgac cttagaagat gatttgcagc
    16201 cagtttatca tgtggcgcag gggatcagtc aacccaccct gattaaggcg atcagatcag
    16261 cctttgatag cggtgcctta gctcagctgg aagaaaattt accagagccc ttgattcaga
    16321 aataccgcct gctgccgaga caagctgctg tttatgccat gcattttcct aaacatatgg
    16381 aggattataa gcaggccctg cgccgtataa aatttgaaga atttttctat tttcagatga
    16441 atctgcaggt tttaaagctt gctaacaagg cagagggcaa tgggttagcg attccttttc
    16501 atcagcaggc agtggcaaaa aagattgctg ctttgccctt ttcactgacc agagctcaac
    16561 aaagaagcct ggaggaaatc ttagcagata tgacctcagg ggctcatatg aaccgtctgt
    16621 tgcaggggga tgtcggctct ggcaagacag tgatcgcaag ccttgccatg tatgctgccc
    16681 aaacagcggg atttcaatcg gcactcatgg tgccaactga gattttagct gagcagcatt
    16741 acgatagtct ttgtcagctc tttccagatt tgtctattgc cctgttgaca tcgggtatga
    16801 aagcagctga aaaaagagca gctttatcgg ctattgctga tgggtctgtg gatatgattg
    16861 ttgggacgca tgccttgatc caagacgcag tgacctatca taagctaggg ctggtgatta
    16921 ctgatgaaca gcaccgtttt ggggttaatc agcgtcgctt gtttcgcgaa aaaggcaaca
    16981 atccagatgt tttgatgatg acagctactc ccatacctag aaccctagcc ataactgcct
    17041 atggtgagat ggacgtttcc attattgatg aattaccggc agggcgaaag ccaatcatca
    17101 ctcgctgggt caagcatcgg caattagata gtgtgctggc ctgggtaaag accgagcttg
    17161 ctaaggggac acaggcctat gttatctctc ctttgatcga agaatctgaa actctagatt
    17221 tgaaaaatgc ggtagcttta gaggctgagc tgaaggatta ttttaaagct tcagctagtg
    17281 ttgccttgat gcatggcaaa atgaaggcag acgacaagga gatgatcatg cagcgcttta
    17341 aggctaagga gattgatgtc ttggtgtcaa caaccgttat tgaggttggt gtcaatgtgc
    17401 caaatgccac catcatgctg atcatgaatg ctgaccgctt tggccttagc caattgcatc
    17461 agttgcgtgg tcgtgttggg cgaggcagca agcaatccta tgctattttg gtggcagatc
    17521 ctaagacaga ctcaggcaag gagcgtatga ccatcatgac aacgactaat gatggctttg
    17581 tgctggcaga ggctgacctc aagctgcgtg gctcaggaga gatttttggg acccgtcaat
    17641 caggtttgcc agagttcaaa acagctgata ttgtagagga ttatcatatc ctagaggagg
    17701 caagacgagt cgctgctgag attgttgcag ctaaggattg gcagctggac cctagatggg
    17761 ctccgatttt ggctaatctt cgtgtcgctg atcagtttga ttagatgtga ggctgacttg
    17821 ctggacagag ctaatataaa aacacgacaa gaggttctta gctgaccgag tcgtgctttt
    17881 tgtgctatag atgaggagta gtagcctgtg attataggag agcttagcct tcgatataat
    17941 ccttcagctc ttgacctgta agcccagcgt tgagggcgat gagcaatttt aacctggcct
    18001 taggggcatt tagctccttg acaaacataa caccagccct ttttaagctg gcaccacctc
    18061 cgcgataagc ataaactggc tctgctatgc cattgaagca gcgcgagacc aagacaacag
    18121 gaatcccaga ggcgattaat ttttcgagct cagatactgc taggggagga acatttccag
    18181 cgccgagggc ctcaatcact agtccctgaa tcctatcagg tgtcaaaagg cttaaaatac
    18241 ttccatctcc cataccagca taggccttga taatcggaac tgtgccagaa atatgacgaa
    18301 gctcaaagcg aacccttggc tcagcagtct taaagaacag taaatcgtcc ttcatgacga
    18361 ctcccaaagg gccatgagtc ggtgtttgaa aggtcgaaac attggtggta tgcgttttgg
    18421 tgacatactt agcggcatga atttcatcat tcatcacaac cagcaccccc ttgcccttgg
    18481 ctttctcatg gctggctacc ctaagcgctg ttaggtagtt atagatacca tcgcttccaa
    18541 tctcgttggc cgagcgcata gcacctgtga taacaatagg caactctaca ggcagcacca
    18601 ttgtgtctag aaaataagca gtctcttcta aggtatctgt accatgtgtg atgaccactg
    18661 catcaaactg actagccctt tgttgaatgt aatgatacat cttgagcatg tggtgagggg
    18721 tgatgtgcgg gcttggcaga tttaaaaaat ccacaacagt taggtggata tgctccaggc
    18781 taaggccaac ctgattcatt ggattgtttt gatttgggct caccttgcct gcttcatcag
    18841 cctgcattga aatggtgccg ccggtatgta agacgaggat ttccttcatt tgatactcat
    18901 acttctttca atttatgata taatttattt tatcacaaat agaagagaga acagaaggat
    18961 ttgacaataa aagcagtctt tttcgacatt gatggaaccc tgcttaatga tcgaaaaaat
    19021 gttcaaaaaa cgacgcaaag ggctattcag caattaaaaa aacaaggtat tatggttggg
    19081 ctggcaactg gtcgtggacc tgcttttgtg cagccctttt tagaaaattt tggcttggat
    19141 tttgcagtga cctacaatgg tcaatacatt ttgacacgag acaaggtctt gtatcagaac
    19201 cagctgccaa agtcaaccat ttataaaatc attcgctatg ctagcgataa aaagcgcgag
    19261 atctccttag gaacagcttc aggtcttgct gggtctcgga tcattgatat gggaaccagt
    19321 ccatttggtc agatggttag cagtattgtg ccaaggagtc tggtcaagac ggttgagggc
    19381 agctttaaaa acctcatcag acgctttaag ccgcaaagct tcagcaatct tgttaccatt
    19441 atgagagagc cgatttatca gattgtcttg gttgcttctg ttgatgacac ccaaaaaatc
    19501 aaggaaagat tcccgcatat caaggtaacc agaagcagcc cttattcctt agatttgatt
    19561 tctagcgggc agtctaaaat caagggcatt gaacgcttgg gcgagatgtt tggctttgag
    19621 ctctcagagg tcatggcctt tggcgactct gataatgact tagaaatgct ctcaggcgtt
    19681 ggtgttggtg ttgcgatggg aaatgctgag gcagtggtta aaagcggtgc tcactttaca
    19741 acagcttcaa ataacaatga tggtatctct aaggcgctgg cgcattatgg cttgattcat
    19801 tttgatgtgg aaaaaagctt taaaagtcgc gatgataatt tcaacaaggt caaggatttc
    19861 caccgcctga tggacggaga cacgattgaa acaccaagag gctattcctt aaaggaggct
    19921 ggctatcgag cagattttaa ggtagaggaa cttgtggaat ttctttatgc agccagtcaa
    19981 ggggataagc atcgcttttc tcaggctttg atagacctcc atgctgccct tgataaggca
    20041 gctaagaagg tgcaggccaa ggagcaccca gagtcacccc tggttgggca ggttgatgct
    20101 ttgacagatc tgctttattt tacctatggc tcatttgtat tgatgggagt ggaccctcag
    20161 cccatttttg agaccgtcca tgaagccaat atggggaaaa ttttccctga tgggaaagcg
    20221 cattttgatc ccataacgca taaaattcaa aagccagatg actggcagga gcgctatgca
    20281 ccagagtcag ccatcaaaaa agagttggac aagcagcttc aaaaatcatt gcagcgcttg
    20341 gaaaaataag gctgtcttta ttttagaggc attaaaaagc accttgagct gtgagttgat
    20401 ctcctagctg ttaagcattt ggcctaacac ttggggtcac ttcacttatt agctcagggt
    20461 gctttttgat gtagactaga caccctcaat aaaagggccc ttaagtctag ctagtggtaa
    20521 ttagtatatg agagcagtag tcctttagta gccttgtgag ctgaggctaa gggctaggta
    20581 tggttacttc acttaggctg caaatgcttc tgacagctga gagaattcgt cttgctacag
    20641 ggttttgtca tgctctcgaa ccactaatag gtcaaccttg gcatgacgaa ggatatattc
    20701 agatgatgat ccaatcagca accgctcaaa ggtgttaagc ccagttgccc caaccataat
    20761 caaatcaacc tcttctttgt cagggatatc gtgcgctaat agcgttttgg gattgccaaa
    20821 ttcaatcacc tgcttgacct cagtcagccc tgcctcgcgt gcttgttttt caaaatcccc
    20881 caagacctct ttagc
//
LOCUS       DARYXZ010000039        20402 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYXZ010000039 DARYXZ010000000
VERSION     DARYXZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20402
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(85..1350)
                     /locus_tag="TV186_001386"
     CDS             complement(85..1350)
                     /locus_tag="TV186_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL1532772.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TV186_001387"
     CDS             complement(1364..2221)
                     /locus_tag="TV186_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532773.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TV186_001388"
     CDS             2564..3856
                     /locus_tag="TV186_001388"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL1532774.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TV186_001389"
     CDS             complement(3971..4744)
                     /locus_tag="TV186_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL1532775.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TV186_001390"
     CDS             4869..5615
                     /locus_tag="TV186_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1532776.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TV186_001391"
     CDS             5630..6610
                     /locus_tag="TV186_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL1532777.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TV186_001392"
     CDS             6849..7169
                     /locus_tag="TV186_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1532778.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TV186_001393"
     CDS             7194..7502
                     /locus_tag="TV186_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1532779.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TV186_001394"
     CDS             7513..8817
                     /locus_tag="TV186_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1532780.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TV186_001395"
     CDS             9098..11515
                     /locus_tag="TV186_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL1532781.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TV186_001396"
     CDS             11530..12198
                     /locus_tag="TV186_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1532782.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     VEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TV186_001397"
     CDS             12323..13414
                     /locus_tag="TV186_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL1532783.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TV186_001398"
     CDS             13921..14973
                     /locus_tag="TV186_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL1532784.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TV186_001399"
     CDS             15002..15580
                     /locus_tag="TV186_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1532785.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15778..16686
                     /locus_tag="TV186_001400"
     CDS             15778..16686
                     /locus_tag="TV186_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1532786.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16922..18268)
                     /locus_tag="TV186_001401"
     CDS             complement(16922..18268)
                     /locus_tag="TV186_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1532787.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(19308..19412)
                     /locus_tag="TV186_001402"
     CDS             complement(19308..19412)
                     /locus_tag="TV186_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1532788.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
     gene            complement(19792..20307)
                     /locus_tag="TV186_001403"
     CDS             complement(19792..20307)
                     /locus_tag="TV186_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEL1532789.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFNCFYRAFKRYLK
                     YRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNNLNNYKAVIKQYPHKTIVLKNQKQL
                     NHYMNSIQHDS"
BASE COUNT         5780 a         4094 c         4555 g         5973 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag caaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggtaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aacaaaacct cggagacaaa ctagccagca gctatttctc atgagtaatc aacatgttaa
    15721 aatcttcttt ggagatatta gacaaccata attattatat catcaaagga gagaaagatg
    15781 acaaacaaaa caaagcgtac aggattggta cgcaagtacg gtgcctgctc agcagctatc
    15841 gccttagcag ctcttgcaag cctgggagca ggtaaagcag taaaggcaga ccagccagca
    15901 gcactaaaat atccagaacc tagagactat tttcttcata ctcgtgaagg tgatgttatt
    15961 tatgatgagg atataaaaag atattttgag gatttagaag cctatttaac agctagactt
    16021 ggtgggattg ataaaaaagt agaagaagct gcccaaaagc caggtattcc aggtcctact
    16081 ggccctcaag gtcctaaggg agacaaagga gatccaggtg cccctggtga gcgcggtcca
    16141 gctggaccaa agggcgatac gggcgaagcc ggaccaagag gtgagcaagg cccagccgga
    16201 caagctggag aacgtggacc aaaaggagat ccaggtgctc caggtcctaa aggtgaaaag
    16261 ggtgatactg gtgcagttgg tcctaaaggt gaaaaaggtg ataccggagc aaccggacca
    16321 aagggagaca agggcgaacg cggtgaaaaa ggcgagcaag gccaacgtgg cgaaaaaggc
    16381 gagcaaggcc aacgcggtga aaaaggcgag caaaaaccaa agggtgatca aggaaaagat
    16441 acaaaaccat cagctccaaa agcacctgaa aaggctcctg caccaaaagc tccaaaggct
    16501 tcagagcagt catctaatcc taaagcacca gctcctaagt cagcaccaag caaatcagcg
    16561 gcaccaacag gtcaaaaagc agccctacca gcaacagggg aaatcaacca cccattcttc
    16621 acccttgcag ctcttagtgt catcgctagc gtaggcgtcc taactctaaa aggaaaaaaa
    16681 gactaagcta gttattgtat ctttcctgta tgacactagc taacagctaa tcacaaacac
    16741 cagagagagg tcttttctga cctctctttt atatacactg agcacatgct tacctcaaaa
    16801 agacagtagt ctaagtttga ctactgtctc aaaaatcatt tttatctaaa gctttgatca
    16861 gcttgacaaa tggtagagaa ggacttgatt tctaaggcct ttgacctcag tttgactttt
    16921 gttaattttc cttacgtttt atagctgcta caccagctgt agccataact gcaagtgcag
    16981 ctgcggtgaa gaatgggttc acagcctcac ctgttgctgg caattgatta gtcgttttct
    17041 tcatctcagc tttagctgct gctgctttag aagctgtgtg agctggcgct gctactttac
    17101 ctgcttgatc agctttttca ggactgagtg gtttagcctc tggcttagtt tctggtttgg
    17161 tttctggaac tttaggtgcg tcttcttgtg gttttgaatg tggacttgat tttttaatat
    17221 ctttagcatc tagggcaacg cttctttcct cacctgttgt agcttgagaa agctttttgc
    17281 cgttgacaaa aatctcatag aaagtgccat ctagaagccc tttagaaaat acagctttgc
    17341 catcagctcc tgttgttact ttctctatca cacgacctac tctatgcttt agagtgactt
    17401 cttgtcctga taaaggttca gcatcttcat tacgaacgat aacaaccaaa ggtgttttac
    17461 tgtattctgg ctcaactgtt ccttttccgt caacagtaaa gctagctgaa tgcttgtcgc
    17521 catcaacacc tgttcgtaca gtatagcctt gaggaacgcc attcacaaaa attgataaac
    17581 ttcttcctaa aggaagcttg tcaaaaacag cttgtccttt ttcatctgtt gtcacagtcg
    17641 caagtgtttt tctgccactt gttatatcta ccacttggac gtcttttcca gataatactt
    17701 taccctcagg gtctataact gttgcggtaa aagcaaagct accttcaata acatcatcat
    17761 gatggtggtg tgcatgatca ctgtgatgac tactctgccc atcgtcaaaa ggcttagaaa
    17821 catcaatctt atccaataaa ataacatgat gatgatcgtc atgtggatac atcaaggcct
    17881 taccctctga agtatccaat aattgaatct tgtctaatgg caagcctgta tttttggcga
    17941 tataagcttt ttttacggca ataatatctt cagctgattg attagtgtct agcggtaatt
    18001 tatcagctgc tgctacagga tttgcggttt ctgatgcttt tgtaattggt ttatcagcca
    18061 tcacctcagt gctgtcagat aactgttgat tagctgtatc tgcagtatct ttatcctcac
    18121 ctaacctcgg ttggactaca gtgtgattat ccactgctgg tgattcatca gcaaatgcta
    18181 ctgacgagtt agttgacatc gctaaaccag cagccattaa agcagctggg ataagtaaag
    18241 agtatcgggt aacttgattc tttttcatta ataactcctt ataactatta ttcattttaa
    18301 ttaattaacc agttaactat atcaatctat caaaaaaaat atagtatgtc aacctcttaa
    18361 agtgatttaa tcagaacaaa cgtatgaaga aaatcatttg gtgaaaaaga agcttatttt
    18421 agctgaaata gatccattat aaaagaggtg tcgtgaagta actcaatatt cacctatttt
    18481 tgtcgcaagt attctaatag gaatagaaaa agggcagttg cttgcaacaa ctacccaatg
    18541 taaaaccgtt aaagacggtg acagaaaata actgttaact gaactacctc aaaagttaaa
    18601 ccaaagatct aaccgttgga tgttggtttg tagagcggtt atttttttat tgttatgttt
    18661 acaacgacta agctcatcag tgtaagggaa agggacttcc atattaagaa gtatatatac
    18721 atcctagatg agacgtgtaa tgaatgggtt gaacaaatag ttgcttaatt ttgggataag
    18781 ggttataata aaaatagaaa aagggcagtt gcttgcaaca actacccaat gcagaaccgt
    18841 ttgagacggt ggctggtttt atagttaaaa gataaccgtt aactcgccaa agttaaggac
    18901 ggttattttt tattgtcatc tttgaagatt tgatagcaca agctgataag cgcaatagta
    18961 aagctactaa agcctaaaag gatttatacc acttcaaaag ctgtcaatgc tttgactcat
    19021 cctttctgtt agattttgat gaactgccca taggcctcac ctacctttca gaaataagag
    19081 ccaccgtctt aacctttctg ctttatcatt atagcatatt gttattaagg ttgactattc
    19141 agactcgtct aaagaagtgt aatagttgct taattttggg ataagggtta taatgaaaat
    19201 agaaaaaggt agttgctcga cacaactacc catgcagaac cgtttaagac ggtggcatgt
    19261 tttatgttat taaaaaataa ccgttaactc gccaaagtta aagacggtta ttttttattg
    19321 tcatctttga agatttgata gcacaagctg ataagcgcaa tagtaaagct actaaagcct
    19381 aaaaggattt gtaccacttc aaaagctgtc aatgctttgg ctcctccttt ctgttagatt
    19441 gtgatgaact gcccataggc ctcacctacc tttcagaaat aagagccacc gtcttaactt
    19501 ttctgccttt ttattatagc ataccctatc tctgattgac tagcttaaga aggaggggat
    19561 gtgatttgga tacaaatttt tgttaacttt tttaaagtct ccaaatgatt taaaaaaatg
    19621 atattaatgc tctaagtaag aatattaata atatggtttt accacttatt gtatgaggta
    19681 tcatttctaa agagttattt ttcagacaga aggcttgtta aagcaaacag aagcaatact
    19741 aaaggcatta gatgataatc aaggcctttt tcatgtctta aaatgagtat actagctgtc
    19801 gtgttggata gaattcatat aatgatttaa ctgcttttga ttttttaaaa cgattgtttt
    19861 atgaggatat tgtttaataa ctgctttata gttatttaaa ttattttttg agcgtccgtc
    19921 taacagaatc catttcataa attcaacatc aaatttttca ttacagtttt cagccatatc
    19981 aggacgtgtt tgtcccctat attttaaata tcgcttaaaa gctcggtaaa aacaattaaa
    20041 tctattaaag ttaaaatata taatgtgatc agcctctctc atacgctctt cataaagaca
    20101 gcttgaataa ttaccttcaa taatccaatg tttttgtgac ataaatgttg atatatcaga
    20161 gaccatttga ctaactgttc gctcttgcca gtttgatgca aaatgaattt tgtctaaatg
    20221 aagtacagca caattgtagt gttgacctaa aacatttgct aaagtcgact ttccagaacc
    20281 actatagcca attattacaa ttttcaatct ttgtctcctt tgtcaatgct gtactttgac
    20341 ttatattata gcataaagaa tatattttgg ggacaaatcc tctttagaca agcaaaaaag
    20401 cc
//
LOCUS       DARYXZ010000040        20022 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYXZ010000040 DARYXZ010000000
VERSION     DARYXZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20022
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..1230
                     /locus_tag="TV186_001404"
     CDS             <1..1230
                     /locus_tag="TV186_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1532790.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLD
                     KKQSNSFNIFRKAGFGL"
     gene            1242..2744
                     /locus_tag="TV186_001405"
     CDS             1242..2744
                     /locus_tag="TV186_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1532791.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2725..4302
                     /locus_tag="TV186_001406"
     CDS             2725..4302
                     /locus_tag="TV186_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL1532792.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4304..4510
                     /locus_tag="TV186_001407"
     CDS             4304..4510
                     /locus_tag="TV186_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532793.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4507..4926
                     /locus_tag="TV186_001408"
     CDS             4507..4926
                     /locus_tag="TV186_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1532794.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5123..5392
                     /locus_tag="TV186_001409"
     CDS             5123..5392
                     /locus_tag="TV186_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532795.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5428..5595
                     /locus_tag="TV186_001410"
     CDS             5428..5595
                     /locus_tag="TV186_001410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532796.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5777..6400
                     /locus_tag="TV186_001411"
     CDS             5777..6400
                     /locus_tag="TV186_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1532797.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6411..6791
                     /locus_tag="TV186_001412"
     CDS             6411..6791
                     /locus_tag="TV186_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL1532798.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6794..7843
                     /locus_tag="TV186_001413"
     CDS             6794..7843
                     /locus_tag="TV186_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL1532799.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7854..8120
                     /locus_tag="TV186_001414"
     CDS             7854..8120
                     /locus_tag="TV186_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532800.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8130..8483
                     /locus_tag="TV186_001415"
     CDS             8130..8483
                     /locus_tag="TV186_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1532801.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8480..8788
                     /locus_tag="TV186_001416"
     CDS             8480..8788
                     /locus_tag="TV186_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532802.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8769..9134
                     /locus_tag="TV186_001417"
     CDS             8769..9134
                     /locus_tag="TV186_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1532803.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9131..9520
                     /locus_tag="TV186_001418"
     CDS             9131..9520
                     /locus_tag="TV186_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1532804.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9530..10121
                     /locus_tag="TV186_001419"
                     /pseudo
     CDS             9530..10121
                     /locus_tag="TV186_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10183..10542
                     /locus_tag="TV186_001420"
     CDS             10183..10542
                     /locus_tag="TV186_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL1532805.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10584..10913
                     /locus_tag="TV186_001421"
     CDS             10584..10913
                     /locus_tag="TV186_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532806.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10930..14184
                     /locus_tag="TV186_001422"
     CDS             10930..14184
                     /locus_tag="TV186_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1532807.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14216..14995
                     /locus_tag="TV186_001423"
     CDS             14216..14995
                     /locus_tag="TV186_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1532808.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14992..17049
                     /locus_tag="TV186_001424"
     CDS             14992..17049
                     /locus_tag="TV186_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1532809.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17049..17756
                     /locus_tag="TV186_001425"
     CDS             17049..17756
                     /locus_tag="TV186_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1532810.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17758..18372
                     /locus_tag="TV186_001426"
     CDS             17758..18372
                     /locus_tag="TV186_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532811.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            18383..>20022
                     /locus_tag="TV186_001427"
     CDS             18383..>20022
                     /locus_tag="TV186_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1532812.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDAAKIRVINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLLNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT         6745 a         3508 c         4504 g         5265 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaaagataaa
     1081 aaaacaaatg agtatattaa cgacccagtc gatagttata accactgcat tgacgcgatt
     1141 aggtatgcga catctaatca tttcttgaca ctggacaaaa aacaatccaa tagctttaat
     1201 attttccgca aagcaggttt cggactctag aaaggagaac aatgttatac acagaaacgt
     1261 ttaaagacag cacaggtaat gctaaattac ttgagtttag attccatcgt gagtctcgta
     1321 tgaggtatca gacaagcgat ttaagcggcc tttttgacga agggtataaa ctattgcttg
     1381 actatatcaa acaccacgaa agcaagcaaa aaccacgcat acaggagctt ttagactatg
     1441 ctgagggtaa taatcataca gtctgcgaat caggccgcag acgagaggct gatatggcag
     1501 acagtcgtgc tatacacaac tacggtaagt atatctcgac ctttaagcag ggctatttag
     1561 ttggaaatcc tatccgcgtg gaatatgagg acaatgatga tgctaaaaaa caattgttca
     1621 aggagctggc ggataaaaat aacttccacc aacttaaccg tagacttgtc aaggatttat
     1681 ccaaggtagg ccgcgcctat gaacttatct atcgcagcat ggacgataag acagaggttg
     1741 tgcgattaga tccacgagaa acctttatta tctatcaagc tgatgttggg caagctagcc
     1801 ttgtgggtgt gaggtactat aacaagagtc agctggatag aacaaagaaa acagttgagg
     1861 tctacacaga taacgagatc atttactttg attatgatgg gcaactgaca gaggttgata
     1921 ggcggccaca catttttaaa tctgtaccta tcacagagta tctcaatacg gacgatggcc
     1981 ttggtgatta tgagacggag ttgtctttaa ttgacttgta tgatgcagct caatcagaca
     2041 cagcaaacta tatgcaagat ttgtcagatg caatcttggc tattattggt cgagtatcgt
     2101 tcccgagtta tgtagacacc aaggaaaaag ccattgaata tctgcgtgct atgcgcaaag
     2161 ctaggttgct aaatttagag ccaccagtgg ataccgaagg tagagaaggt tctgtagatg
     2221 ctaagtatct ctataagcaa tatgatgtca acggcacaga agcttataaa gatagggttg
     2281 tgcaagatat ccacagattt accaacacac cagatatgtc agatagcaaa tttgcaggca
     2341 cgcaatctgg agaggcactc aagtggaaag tctttgggct tgaccaagag cgtgtagact
     2401 tgcaagcact gtttgagcaa tctctaaaac gtagatataa gcttatcgca agagttagtg
     2461 agctgttaaa agaaattgac ggatttgaca ttagcaaact taaaattact tttaccccta
     2521 acttaccaaa atcgctacat gaaaaaattg aagcttttaa agcacttgga ggggagttgt
     2581 cgcaaaaaac aacaatgtct attacagata ttgtggaaaa tcctgataaa gagattgctt
     2641 ccatcaacga tgaggctaaa aatcgtagtt tattggcgca aaagatggag tcagaaggta
     2701 gaatgacgga tagggagtta gctcgtgact acaatcatga ataagagtaa atattggcgt
     2761 gatcgtgtta aaaaagaaat ggacgcaaaa gaggcagatg atatctccct tgaacagtcc
     2821 atgaaacaat tacacaatta tcattttaga aatatcgaaa aagaaattga gtcattttat
     2881 caacgttacg ctgataaaga gaaaatagac atcgcagaag cccgtaagag agtttctgag
     2941 cttgacattt ctgcttacca gaagaaagct aaggaacttg ttgtaaaggc tgagaagcta
     3001 cgaaaagagg gtaagacagt aacgagagat gactttaccc accaagaaaa tgcagacatg
     3061 gccatctaca atttagcgat gaaaactaac gctttagaat tgttgcgctt gaatatcgac
     3121 ttggagatgc aggagctcgc aaatggcgaa cataagctaa ccaagacatt tcttgacgaa
     3181 ggataccgca aagaggttga gttccaagcg ggattgttag gactgtcggt tgctagccaa
     3241 gcaagcgtga aagggttggc tgacgcagtt attaacgcta atttcaaagg cgcaaaatgg
     3301 tcggatagca tttgggacag acaagataaa ttacgcagca ttatatccca gagcgtacag
     3361 agtgctatct taaaaggtaa aaatggttta actattgcaa gggatattag acgagagttt
     3421 gatgtgtcag tgtcttatgc aaagcgaata gcaatcactg agcatgcaag ggtgcagatg
     3481 gaagttagta gattatccat ggcggagaat ggctttgcta tgtttgacat tatcccagag
     3541 cctaaagcat gtgatgtttg taaagacatt gctaaacaag gtccatatca catggataag
     3601 tggcgaacag gggaaaacac gccgcccatc catccttatt gcaggtgtgc agttgttgga
     3661 gtggaagaag aaaatagtag taatcatgaa tcacttgata agcttattaa aacagagtat
     3721 aatcaaagta tgaaagagtc atcgacttat gctcgtaacg ttttgtcggc agtgtcattg
     3781 atagagcctc gaattacatc gcaaattaag catattgtca agcaatccaa cggtaattta
     3841 caaggacttg attttagatt aaaaagtcta gattctttgg ccagaaagat ctctactgat
     3901 agcttgttgg acgatatttc accggaagaa gccgcaaaca acataaatga tgcattacgc
     3961 tatacagctg tatttaaacc agataatttt tttgatgatt atcatagcat gaaaaatgca
     4021 ttggtcagag atggttttaa aatcgaaaag gtgaaaaata cttggctaga tgatggtcca
     4081 tataacggtg ttaatactgt tgtatcaaaa gacaatgtca agtttgaaat tcaatatcat
     4141 acccaagaaa gctttgattt aaaaaacggg aaactgcatg aattatatga ggagagaaga
     4201 cttcctaata taacacgaaa acggaaggct gaactagaca aaatgatgtt tgagcttagt
     4261 aaatctttaa ctaaacctaa ccaaatagaa agggtgaatt gatatgatta caaaatattt
     4321 ttttataaaa accgaacacc ccaaaattgt tagatattct aatgggttaa cagaagttta
     4381 taacagcgca aaaggctggg aagaacaaga agcttggtac gatcgtctat tctttagcga
     4441 tttcagtgat tttgaagagg ttacagaaaa agaagctaaa atgtttattg cgggattgac
     4501 agcggcatga gtattgtgga gctagctttc agagtggcta aaaaagccca ccttggacag
     4561 gttgataagg ccggtgtcga ctatattaag caccctataa ctgttgcaag ttttgtaaaa
     4621 actgatgaag aaaaggcaac ggcttatctt catgatgtta tcgaagatac aagtttgact
     4681 ttacttgact tggaagagta tgattttcct cgaagtgtta tagaggcagt tgatatactg
     4741 acaaagaaaa aaggacagga ttatcaatcc tatctaaacc ttgttaaaac aaataaactt
     4801 gcaagaactg taaaattagc tgatttaaaa cacaattctg atttatctcg tctctctgaa
     4861 gtaactaaca aagatttaaa acgctataaa aaatatcaag aagctatcaa atatttaaac
     4921 aattaaacaa caacagacgg gcaaccgtct ttttttgtac cccaaaaaca ggaggaaatg
     4981 atgttgaaaa tagtgaaatt tttgaaatat gtttggattt ataagtgtaa acctgtcagt
     5041 ccaagtcttt atgcatcgag tcggattgag tacttcaaac ctcttggtta ttactgggaa
     5101 aaagcaacga taggagaaag caatgaataa acgaatcaaa aagaaacgta aactagaaac
     5161 agtagtagtg atgctggttg cggaaaatgc cttgcaggct gaagcgctca taaatcaaaa
     5221 caaagaaatc atggagctaa aatcaatcgt tgagcgaaac gctctggcaa caaacgaaga
     5281 gttagcgact gttaaagaca ccgttttaga caaccaatca gttatcaagg caattggtga
     5341 cacggttgac tacatcaagc aaaattacaa acgtaagtgg gggaagaaat gaagtatctc
     5401 aagaaaaagt aatagtaagg agttattttg aaagtcaaag agatagcaca ggtgtttaat
     5461 gaatattcgg atttttttgt ggtacaaaac ggtaaatatc tacctggtga cagaactagt
     5521 ttttttctag attgcgaatt ggaaatcaaa gaaatatcta tcggaattcc tgattgctta
     5581 attattgaag tataaaaaat tcaaagtcgt agcaatacgg ctttttattg tgccctgagc
     5641 atggcctaaa aaggctcaaa ttaatcacta gcgtggcttg tggataaata cacctaatag
     5701 agactagaaa acatgaggcg cccgttttcg tggctctgca gtgtgtttaa aagcaagact
     5761 agcgtgggag gaaaaaatga ataaaaaact attagaaaaa ctttttaaat gtgctccaga
     5821 tactggcaca ggttcaggag gagcttctga tgcagatagc caacaatccg aaacagatgg
     5881 agaaccatct agtgaagaca gctttaaagc tccacagtcg caatcagagt tagatagcta
     5941 tacgaataaa gcaatccaaa aggcattgga aaatcaacgc aaagatgaag ctaaacgaat
     6001 agaagaagct gtaaaagctg ctttagataa agaaaaagac tactccaagc tatctgaaga
     6061 agaacgtcag cagcgtgaat ttgaagatag taagaaagcc tttgaagctg aaaaagccaa
     6121 gtttgaacac gataaacttg tagtccaagt cgaaaaggat cttatcgcaa agggattgcc
     6181 ttctgagttt gctgaattgc ttgctacaaa agatgcagaa aatgcgctag agcaagtcaa
     6241 aacattcgaa gcagcattta aaaaagcagt agctgatgaa gttaaaaaga ccgtacgaca
     6301 acttactcca tcaactgggg caggtgcaat atcaacacaa acaaactatg gggcgaactt
     6361 ggcgagtaag atcgcacaac aaagcaccac attattttag gaggaaaaaa atgaataaac
     6421 gtaaagtaac aacatcaaaa gagattctcc acaatctcga atacgaagct attacagtca
     6481 ctttagattc aagcacagtt ggcaaaaaag ttattccagc cggtacagtt ttggccggtg
     6541 tatcggattc tgtttttaaa gatcgcaaac aaaaagtaaa aactgtggca aatcacgagg
     6601 tcagcggaga gagcaatatt tgtggaattt tgttaaccga tgttgatttg acagatggtg
     6661 ataaagcagg tgcttgtgtt tatcgcggta ctgtcaacgc agataaactt gctgattcat
     6721 caattgcaga aaattttacg gaattggcga caaaactacc acatgttgtc tttattaagg
     6781 gaggtaagta agcatggcat tgatccacga aattatcaca tcggaaaaca tcaaaggttt
     6841 ttataatgct aaaaatgaga acattgataa aacgttaggg gaaaaagcat tcccaccaaa
     6901 acagcaatta gggcttaagc tatcctttat caagggtgcg gcaggaaaac ctgtgacact
     6961 taaagcggcc gcttttgata ctaaagtacc tctacgtgac cgcatggcag ttgagctgct
     7021 tgacgaagaa atgccttact ttaaagaggc tatgcttgtt aaagaggcag accgtcaaga
     7081 gcttaacatt atatctcaaa caaaaaatag tgatcttatt gacacagttt tagcggcaat
     7141 ttataacgat aaggtaacgc ttatcgcagg cgctaaagca cgtttagaag caatgcgtat
     7201 ggaagtgctg tctaaaggta aaatccacgt cgcatcaaac ggtgtcatga aagactttga
     7261 ttatggacta gactcttcgc aaacaactaa gccaagtgtt aaatggtctg aggcagagac
     7321 cgcgacacca cttaaagaca ttgaaggtgc aattgaaaaa atggcagaac gtggctttgt
     7381 gccagaagca attatcatga actctaagac atttagtttg attaaaaacg ctaaatcaac
     7441 tcttaaaatc atcaaaccaa tggcaccaga tggggcagct gttaccaaag gtgatttgac
     7501 gacttatatt gctgatgaac taggactcaa aattttgttt aaagatggta tgttcattgg
     7561 tgacgatggc aaatctcgta agtatttccc agatggcttt gcaactttgg tacctaacgg
     7621 caaccttggc tacactgtgt ttggcactac tccagagcaa tcagatctca tgggtgggca
     7681 cgcaacagat gcagatgtgt cgttggttga gactggtatt gcaatcacaa ctactaagac
     7741 aactgatcca gtaaatgttc aaaccaaggt atctatgatt gctttgccgt cattcgaacg
     7801 attggaagaa gtgcaaatta tcgactccat tgaccaagta taaggagggg gttatggctg
     7861 aagttattaa aacttttagg gataaagaaa ccactaacac ttactacgta ggagacgatt
     7921 acaacggaga ccgcattgat gagttgacag ctaaaggata cctatctggt gataaggttt
     7981 ctgctgccgc tatagagatt gaccttgaca aattaaaggt tgacgaaatt agagcaaaac
     8041 ttgatgagtt aggcgtcgct catgacccta aactaaaaaa gccagaatta ttagaacttt
     8101 tgaaacagtc agctagctag gaggtgttta tgcaaaagat aaacacagat agcattatag
     8161 ctaacgtaaa actcgattta ggtattgatg acaccttgca agacagtttg ctcaatatgt
     8221 tgctaaaacg tgttacagac cattttaaag cggaatacgg cgttgatgat atagacaacg
     8281 ccttttcgtt tgttttggaa gactgtctaa ttgctaggtt taatcgcaga gggtcagaga
     8341 gggctaagtc ggaagaggta gagggtcata aaacaaccta ctatgacttt ttaaatgagt
     8401 ttgagcctta cgacaaaatg attaagtcca accttaattt gattaaggat aattctcgta
     8461 aagggggatt gtacttttta tgagatatgc agataggatt acgtttgtta aggcgacaga
     8521 tgaacaatat gaccctgatt taggtgagta cacatatacc gaagtcatga tcaagacatt
     8581 gccttgtttt gtcatggact taggtatggc taaatctgtg cagattttcg gagactatca
     8641 aaaaacacga aaagttgttt atttgcgcca accttatacc gatttgttag atcactgtct
     8701 ctacaaaggc aaaaagtaca aggtacaggt ggataagcaa tttaatactg ttttttatct
     8761 ggagggagat gattctattt gtagctgata tatctttaaa agtagttgga acgacagggc
     8821 taaagaataa acttgaactt attgccaaaa aagaggctgt caagaagatt gttagagata
     8881 atggaaaaca actacacagg aaaatggtcc aaaaggcagt atttaccaaa ggtcattcca
     8941 ctggtgctac cagaatatcc atcacaatgc agattggtga tgatggtttt agtgttacag
     9001 taaaacctgg cacgcattat gcaggttatt tagaaaaagg cactcgcttt atgagtaagc
     9061 aaccttttgt gttgccagct ctaaaagagc aaaaagtaaa attcagaaaa gatttggagg
     9121 cgcttgtcaa atgattaaaa ctagagatca atctattttt gacgagatgt ttaagcgtat
     9181 tcagtcttta ggttttaaag tttatgatta caaaccgatg actgaggttc cttatccgtt
     9241 tgtggaaatg gaatctactg atgcagaata tattccaaat aaagatgaca ttaaaggctc
     9301 tgttgacctc gtactgtctg tttggggatt gcaaaaaaaa cgaaagcagg tgtctgatat
     9361 ggcatctgct attttttcac aagctatgtc agtggctagt tctgacagct tttactggtc
     9421 gttaaatatt cgtcaatcat ctatccaagt gttagatgac acaacaacag tgacacctct
     9481 caagagagcg attgtcacat taagatttaa tttaagatag gaggtcgcaa tgccaggacc
     9541 aagtagatta ggatccaaag atgaagacca ctccacacaa gaaaggaagg aaaaaatggc
     9601 agcgcaagat caagtacaat tagaagcaaa acaagggatt catgcaatcc tattattccg
     9661 tttgttaaaa gaagcatcat cagaaaaagc agctaaactc gcttttcaaa cggaacacga
     9721 agttggtaaa agtcgtgatg tcgacggtca aaagactaaa gatggtatta tccagtctgt
     9781 cggagcttta gaatacgact ttaaagcaac atctatttta gccaaaggtg acaagttagc
     9841 agcaaaacta gaagaagcca tggaaaaagg tgagcttgtt gaaatttggg atattgattc
     9901 cgaaaaagca agtgaagaag cttgatagca aaggtaaata tccagctacc tattaccaag
     9961 gttacatttc aagtttcggc gctaagaaaa atgcagaaga aaatattgaa attgaaatgg
    10021 aatttgccat taatggcgtt ggtcaaaaag gatttgcaac attgaccgaa gaacaaaaag
    10081 cagctgtaca gtacaaattt aaagatacaa cagcaggtta atcaacaagg ccagttaatt
    10141 actggtcttt tatttttaaa tttttaaagg gggaaaagaa taatgcaatt ggaaattaaa
    10201 ggtaaaactc ataacatcaa atttggcaca cgatttgttg ctgaaatgga taagaatcac
    10261 attgcagaac gtgaagggat gaagtttggc gctggtttgc aatcaactgt tccgtttttg
    10321 tttgagcgta acgttgtgac acttgctgag attatctata cagggacaat cacagagtca
    10381 ccacgaccaa gcttaaatga tatttacgac tacatcgatg aggctgaaga tattgagaag
    10441 cttttcgatg atgttttaga tgagttgcgc caatctaacg cgtcaaagtt gtttatcacc
    10501 aaactggaca aaaacatagc ggagatggca accgaagctt aaagagttca accaaaaatt
    10561 attcttcaca agaaagcttt gagatgattg tccttaattg tgttagatat cttggcatga
    10621 ctgacattaa tgagattggt cggttgactt tgtatgaata tgatttattg atgataggta
    10681 aagcgctagc ctctgtagac gaggcatata aagctcacaa gcaagcttgg ataaatcacc
    10741 aggtctcagc tacgaggctg gtcggtggtg gtaaaaacaa aagagaagtt cctgtttata
    10801 aaacattcaa ggaatttttt gattatgaaa cagaaatcaa gaagataacc aatgaaattg
    10861 atgaaagcta tgacaagaaa gcaatggatt tacttttaaa agccaacctt taaatagaaa
    10921 ggaagttaaa tgggagaatc ttattcagtt gaagcggtgt tgacagcggt tgataaaacc
    10981 tttggtaaga ctttaaaatc agcagttcaa tcaattgaag gactagaaaa gcgttcaaaa
    11041 ggcttctcgg cggtgtctca aaaggctggg tctatgttta aaagcatgct tggagctaac
    11101 ttagcaggtc aagctattac agcgctagga cgtacagttt catctggact tatttcgatg
    11161 atcggcgaaa tgaatagctc agcaaaagcg tggaaaactt tcgatgccaa tttagcagat
    11221 atcggatttg gcaaacagca aattcttgaa gctaaaacag ctatgcaaga ttacgctact
    11281 aaaacaatct actcagcatc agatatggcc agcacatatg cacagttagc tgctgttggg
    11341 gtaaaggata ctgggaaact cgtaaaagct tttggtggtt tggctgcatc tgctgaaaat
    11401 ccaaaacaag ctatgaagtc aatcagtcag cagatgacac aagctgtggg aagacctaca
    11461 gtagcgtggc aagatttcag aataatgctc gagcaagctc cagctggtat ggctaaagtg
    11521 gccaaagcta tgggcaaaaa ccttaatgaa cttgtagccg acattcaggc tggtagagta
    11581 aaaactaaag acttcctaga agcagtaaaa caagctggta acgacaaaag cttccagaag
    11641 atggcgactg aattcaaaac tgtggaccaa gccattgatg gcatgcgtga aggtttatcc
    11701 aataaattgc aaccagcttt tgaaaaagtg aaccaatttg gaattagagc gattgaagca
    11761 atcgggaaac aactcgataa aatcaatttt tccaaatttg ctgcaggcct tggtaaattt
    11821 ctcgagggcg tgaacattga tagtattatt tcaagaatat caacatcaat ttcatctatc
    11881 gtttctaaaa taaaaggatt ctgggacgga tttaatcaaa ctggagcaat cagcgctttt
    11941 tccggtgctt tacaaagtgt ttggggagcg ttaaaaaata ctgctaaagc catgagtgga
    12001 ggaagctgga agaccttcgg gtcaatcatt ggcgaaattg ttaaacatgt ttctaatttc
    12061 gcaagagtga ttggagatgt cgttggcaag atggatccga gtagactaaa aagctggata
    12121 gctactcttg cagctgttgg tggtggattg aaaatctttg agaaattaac aggtcaaagt
    12181 gttattggat cttttttaga caaaatcggc tcaaaattca aaatatttgg aaataaagcc
    12241 aaagaaggga cagaacaagc ctttaacgga gtcaaaagaa gtggtggcat tatcagtaaa
    12301 atctttaacg gtttgggtaa tatcgttaag tctgccggta cagcgatagc gactgctgca
    12361 aaaggtatcg caactggttt ttctatcgcg tttaaggggc ttgggtctgc catttctatg
    12421 gtaccgccag ctacatggct agctttagga gcagctattt tagcggtagg agcggctttt
    12481 gccttggcag gaactcaagc tgatggcatt agtcaaattt ttaaaactgt tggcgatgtc
    12541 gttgtacaag ttttacaaca ggtcactaac agtctagcta ctctaattcc tattattgta
    12601 agcgctattg gctccatatt accaattgta gcaggggcta tttctcaagt cgtcgcagca
    12661 gttgctggcg gattatctca gattattaca gctgttgcta atggtgtatc aactattatt
    12721 ggggctttca caggtctact tggtggtgtt tctagcgtca ttacctcaat tagtggtgtt
    12781 atccaatcgc tggcaggtgt aattacctca gtatttaatg gcatagcaac cattatttcg
    12841 tctgtagggt ctgcaattaa agatgtatta acgggtctcg gcagtgcttt taaaggattc
    12901 ggcaacggtg taaaatcagc cttagaaggc gttgggacag taatcaaatc atttggtagt
    12961 gcagtcagaa atgtccttga tggtgttgcg catattttcg attctatggg taatgcagct
    13021 cttaatgctg gtcgtggcgt caaagaaatg gctaaaggca tcaagatgct tgtagattta
    13081 tcgcttgctg atttagtcgc aacgcttgga gcagtcgcga caggtcttgg gaatatggct
    13141 ggctctgccg gtcagatgac tacgttaagt tctgccatga gcgaagtagc caatggtatg
    13201 gcgcgtctag gaacaagcgc tacgatagca attactggat taacagtttt tgctactact
    13261 ataacaacta ttcagaccgc aattgcaact ctaccaacaa tcctaactgc agccgctagt
    13321 ggttttaggg agatcgggga ttcggcaact gcagcagttg gtcgaatcca gacttttgca
    13381 gctggtacaa ctgttgttgc atcagcgttt gctagtatgc aatctatgat tcgatctgcc
    13441 atggctgcaa tagtaagcag cattataaca tcatttaacc aagctgcctc tcaaatacaa
    13501 tcaattttat ctcgggtgct atctcaagct aggacatttg gatctcaact agagcaacaa
    13561 atgaggcaat cgggacagcg ttcaggacaa aatcttgctc aggggttgtc ttctcaacaa
    13621 ggtgctgtta ttaatgctgt ttctagcatg gttaatgccg cggtatcaag agcaaatgca
    13681 ggtgctagtc ctatgcgtca agctggagcg tacatcggac aagggcttgc gcaaggtatg
    13741 tattcagcgc taggagctgt aacagcagca gcaaacgctc ttgtagcaca agctgagagg
    13801 gcagcaagag ctaaggcgat gattcactcg ccatctaggt tatttgcaaa acgagttggt
    13861 caatatatcc ctcaaggggt agccatgggg atatataaaa acgctgatgt cgttgatgat
    13921 tctgtaggtg agctatttga tagtatcaat agctttgatt ttaatattgc ggatagattg
    13981 acaagtattg gcgctagatt ccaaggtgtt gtcaaatcag aaagttcgca atcgttgtcg
    14041 cagcaacaag agtttgtaca tacagctcaa ccagcgtatg taaactttag tttaggcgga
    14101 aacgaatacg aagcatttgt aagtgacatc actaatcgac aagcaaaaat tgaaaaaatc
    14161 agactaaaga gaagcagctg gtagttgttt ctcttagttt tatgaaagga gtaaaatgta
    14221 cgaatttaac gatactatca gagggactcc gaaagttact ttcaatttaa aaacaacaat
    14281 tggcgaaaag gtattagaag aagagctcaa taatgattta ggtaccttta ggacattgac
    14341 cgtttctggt cgtgatatgg tggacttaga acaccagaca acaagtgttt tagggcgaga
    14401 tggcgagtat ttccacaatg ccacagttga agtcagaaaa ctagaaataa aagctaaaat
    14461 tactggaaaa gataaccggt caatgcgttt gcaatatgaa aaattaaaca gattaattgt
    14521 tagtcataat caagtttttt tatcattttc agacgagccg gacagaaatt atctaggcat
    14581 ctttaaatct aaagatatac cagaagaagt ttctaacgaa caaatcattg gcttggtttt
    14641 catctgttat gatccattta aaatgtcaga tataaaaacc aaaaaaggta atactgttca
    14701 aaatgatggc ctatttaata caaaacctat cataactctc aacctctcat catcaacaaa
    14761 agaaattagg ctgctacacg tcgaaagtca aaagtatatc agattaactg gtacttatac
    14821 tactgacgaa atcaagattg atatgacaac aggtaagatt acccagaacg gccgtaatat
    14881 tcttagtgat ttagacatgg ttaacagtcg ctattttgat ctattacctg gtaaaaacac
    14941 tttgcagtgt gataatgcaa cgattacagc tgatttcagg gaggtttatc tatgatttat
    15001 ctctttgata agctggagca attagttgct actgttggta ctgatgactt gctctcatgg
    15061 cattttaagg tcaaaaataa tgattgggat caagctagtt ttgaggtacc tgttgattat
    15121 gacattgagc cttttgttta ctttggtttt tttaactatg atccaagcca aaaagaggac
    15181 gtttttaaac tctttaaagt cattgattac aacctagaag atagcaagta ttataaaggc
    15241 ttagataagg ctgagagtga ccttgatact attgctatta tcaaagacaa gcgctttaga
    15301 caatcgtccg cagatgcttg tattgatgga gctttagagg gcactggtta tcaagttggt
    15361 aaagttgagg gcatttccga gatcaggacc cttagctatt attacatcag cccacgagct
    15421 gccatgatca agatgataga agcttttaac tgcgaattta atgtcagata cacctttgtt
    15481 aataacaaaa ttactagtcg ctatatcgac cttaaaaagc gatttggcaa gccaacagga
    15541 aagcagtttg agcatgggaa taacttatta aaagtcgtct atgaggaatc aacagatgac
    15601 atcgtgactt gtctgattgg ccgaggcaag ggcgaggaaa tccaatatga tgaaccagag
    15661 gcaaaggaag ttgaaggaca cttaccagag gcagaaaagc gtcaaggtta tggccgaaga
    15721 attgaattta gcgatgttgt ctggtcagtc gaaaaaggcg actcgataga caaaccagct
    15781 ggtcaaaact ttgtggcgct agatagtgcc agagaagaat acggattgtc tcaaaatggc
    15841 gagctaaaac accgatgggg ggtctttgtc aacgaggaaa ttgaggacaa ggcggaactc
    15901 ttaaaagcca catgggatca attgcagcgc ttatcaatac ccatcagaat ttacaaggcg
    15961 gaaatcttag atattggccc cgaaacgtgg aaaggtgact cagtagccat tatctacgat
    16021 gaggtaaaaa tagcttttga aactcgtgtt gatgagattg atattgataa gctaaacttt
    16081 aacaggtcgg tagtaactct cggtgattat agcgttgtcc aaaaccgcga agcaaggtca
    16141 cgcaaggaag ctgtccaaaa catgatcaat gatagcatag aaaacatcac cggccttggc
    16201 atgaacttac aagaattttt tcaaggtatt gaggaaaaaa ttgccactgg caaaaaagag
    16261 atggaagaca attggcgtaa ggttaacctt gaatttgata actttaaaaa attaatcgaa
    16321 caagagggac gtaactttag agagcgttta gaagctgaaa caaaggaact agatgaacgc
    16381 aaccaaaaag aactcgatga atttcgcgaa accctcaaaa atctgtcgct gcccgaggaa
    16441 gccattaaaa aaataaccga ggccatcaaa gttgatgata tcccatcgct aaaacaaagt
    16501 tttgacgagc tcaaaaacga agtcagcaag aacagcgaaa aatctcgctt aaatgctgaa
    16561 atcatcggca cgaacggtaa gacccgctat aacaaaaatc tcttggttgg tgaacctaat
    16621 cgcaccaaga cctatgatca ggattttgtg gagatagaag caaatgacgg tggttttaga
    16681 cgcggtgaga catacacgat tagctttagt cagacatgtg agttgctaaa aaaagtggct
    16741 atcacgctga cgcagccgca taacaaaggt ctcaagctgg tgctgacacc aaccaaggct
    16801 aagatggagg cgcagacttt tgacctaacc aaggacatag aggttatcag cgtctatcct
    16861 ttgagctaca gagctgtttt aacaggtgac tggtataaat ctaagcagat ggattttaat
    16921 gcggcagaag tgcaggattt agctctggag atgtcttata gagacgttgt cgatagcaat
    16981 aatgctagtt tgattttgga ttggtcctca aatccagatg ttatttttga tggaaatgga
    17041 ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg acaaaaaacg
    17101 agtgggagtc tagtgacatc attttgccac aaggccagct tgtctatgag tctgacacag
    17161 gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat caaggtggac
    17221 cacctggggc acaaggtccc caagggccag ctggcgaaac cggtccacaa ggcccaccag
    17281 gccctactgg tcaacgtggg gaaacaggcc cacagggtcc acctgggcca caagggccgc
    17341 caggagcgga cggtaaaatg acgtttgagc agctcacacc agagcaaaaa cagcagctta
    17401 aaggtgctgg catacaaagc atatcattgg attatgaggg ctatttgaca atacagctag
    17461 ataatggcca atcgtttaga tcagatatta gcttaaaagg tcctcaagga gagccgggga
    17521 tcaatggtat ggacggtcca agaggcgcaa cgggtcccca aggaccagct ggtgatccgg
    17581 cgagcatacc tgacgatgtt gtcagacgtg gtgagttagc tgcatatttg cttaaatcag
    17641 agtataaagc caaaggcgca ggctctgggc taagctacaa agttgtcact caatcagagt
    17701 atgatgatct gtatgattac agcgacaatg agttgatact cgtgacggag ggttgacatg
    17761 gcatataagc tttacactaa agctgatgtt ggtgacaaca tgttgcttgt tgttggccat
    17821 ttgcctgaca atacaaagcg attaaaaatc cagcgtgaga cgttagatgt attgagtatt
    17881 acccactata gctcttatga tatggtacaa ctcaagtcga cagtcaaaag atcccacagc
    17941 aaaaatacag ttgttactct tgtagctgca gctgctagca agcccaaagc taagccaaag
    18001 cacgttttaa actttgctaa ggctaataag gtctatctag gcagcactcg tgtaatagcg
    18061 gtttatctgg gtgatcgact gctctggtcc gacaaagaca gcagcgggaa caaaactgtc
    18121 tctgttgtgg ggagtcttga tatcagacaa tcacaaaaaa tgctgtattt gtacttaata
    18181 gcgtcagaca ttgcagatgt caaaagcaag cgcattaaat cgatagcgat aaatggcgtt
    18241 aacctgtcaa gcgctgcaca aatcaatttt gaggatagcg actattattg tctagtgaca
    18301 atcgagcgag ttgctaacat caaagagatc aaaaatatag cgcaaaaaaa caaaatcacg
    18361 ctagagtttt aggaggtaac aattgagcag agacccaaca attgtaatag acgagacaaa
    18421 cctcgttatt ggcacagatg gccgcatgca ttacacgttt actgctagtc aagacaacca
    18481 aaaggtcagg ctaaaaagca actgtttagg cacagcgcat tttaaccagc tgatgattga
    18541 gcgaggagac caagcgacgg actacgttgc gcccgttgtt gttgagggta caggacaggc
    18601 aacaggcgtc tttaaaagtc tcgaggagat gcttagtggc ctaaagtcaa ttaaactgga
    18661 gctaacagat accaaaaact caaatctgtg gtcaaaaatc aaattgacga caaatgggct
    18721 tttgcgtgag tatcatcatg atcatatctc gaccgagatt gtcgagacag cagctggtat
    18781 tgccaaacgg attgtcgatg atactggcca aaagctggca ctaatcaatg agactatcaa
    18841 aggtgttaag cgtgagtatc aagacgcaga tagacagcta tccgcgagct atcaagcaag
    18901 tatcgatggc ctcaaagccc agctggccaa cgacaaaatt ggcctacaag ctgagattaa
    18961 gctgtccgcc caaggcttgt cgcaaaaata cgacgatgag ctgcgcaagc tatctgccaa
    19021 gattacaacg acatctagtg gtactacgga agcctacgaa aacaaactcg agggcttacg
    19081 ggctgagttt actcgtagca accaaggcat gcggacagag cttgagtcgc aaatcagcgg
    19141 cctaaaagca gtacagcaat caactgcaaa acaaatctca caagagatca aggatagggc
    19201 aggggctgtt agtcgtgtgc aacaggatct agatagttac caaagacgct tgcaagacgc
    19261 agaggataat tacagtagct taacccagac cgttaaaggc ctgcagtcaa ctgttagcga
    19321 tcccaaaggc aaaatccagt cacgatttac acagctgcaa ggtcaaattg agcatcgtgt
    19381 gactagagat ggggttatga gtatcatcaa cgagtcaggc gatagcatta agctagcgat
    19441 ccaaaaggct ggtgggattg atgctaagat gagcgctaaa gagattatct cagcgattaa
    19501 tcttaatggt tatggcgtca gaatctccgg tgagcgtatt gcgctggacg gtaatacgac
    19561 cgttaacggg gcttttggag ctaaacttgg tgagtttatc aagctcaaag ccgatcaaat
    19621 tattggtggt tcgattgacg ctgctaagat tagagtgatc aatcttaacg ctagcagcat
    19681 tgtcggctta gatgctaact ttatcagggc taaaatcgaa catacgatta caagtttgct
    19741 tgagggtaaa gttatcagag ctcgcaacgg agcgatgatg attgacttgt taaactctaa
    19801 aattgacttt aacagcaacg ctaccattaa ctttaataac aaggacaatg cgcttgtacg
    19861 taaagacggt acccacacag cctttgtgca ttttagcaat gccacgccaa aaaattatac
    19921 aggtagtgcg ctttacgcct cgatcgggat aacctcgtca ggtgacggga ttaacagcgc
    19981 gtcgagcggt cgtttttgcg gtgctaggtt ttttaggtac gc
//
LOCUS       DARYXZ010000041        19997 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYXZ010000041 DARYXZ010000000
VERSION     DARYXZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19997
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..159
                     /locus_tag="TV186_001428"
     CDS             <1..159
                     /locus_tag="TV186_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532813.1"
                     /translation="TYAVTDKRLFREHEFATKREAMQFIRELELANDKRATEYYLREW
                     RDANGRYV"
     gene            137..421
                     /locus_tag="TV186_001429"
     CDS             137..421
                     /locus_tag="TV186_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEL1532814.1"
                     /translation="MLMEDTFKKIKELEAACQDRTDNIKKPSHYQGRHGMEAIDVVKN
                     FAACPEHEEGFYWGNAVKYLLRYHAKNGVEDLKKARQNLDWLIEKLEEVE"
     gene            446..658
                     /locus_tag="TV186_001430"
     CDS             446..658
                     /locus_tag="TV186_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532815.1"
                     /translation="MSFRLSWEINGQTVEVIGDYKTLKAAYDSIKVHVKDRDKFASPY
                     YRIWQKGAVHFVDYGKHNAFYKIEER"
     gene            663..863
                     /locus_tag="TV186_001431"
     CDS             663..863
                     /locus_tag="TV186_001431"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532816.1"
                     /translation="MMDTETLEAVYDALQLSLPKIIDMLKAASATRDDAYKEGVLDGA
                     DLIADTVIKAIGQMIDPEADHG"
     gene            856..1083
                     /locus_tag="TV186_001432"
     CDS             856..1083
                     /locus_tag="TV186_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532817.1"
                     /translation="MAKDDFLTGFVLTLLAACVFAAGFVIGSDCSSEHYEQQMTDLRM
                     QLVSTQQQLKQSREQNQRQTKRIAELTGNGG"
     gene            1094..1783
                     /locus_tag="TV186_001433"
     CDS             1094..1783
                     /locus_tag="TV186_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1532818.1"
                     /translation="MEIKCGNCLQLLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGFDLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLVVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVAGLEKTQH
                     PTQKPVALMRDIITRHTTKGAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAK
                     KRIAELTGNGG"
     gene            1787..1969
                     /locus_tag="TV186_001434"
     CDS             1787..1969
                     /locus_tag="TV186_001434"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532819.1"
                     /translation="MPELINTADLQTPIEALENNLDFFKSFYNDERFEDMENAKKLIE
                     RYEKAISILTEVQNES"
     gene            1959..2117
                     /locus_tag="TV186_001435"
     CDS             1959..2117
                     /locus_tag="TV186_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532820.1"
                     /translation="MKVKDLHKVLAKVDPELEVWINEKDGGVITKAKNVMTWNEHPNK
                     FFINAETQ"
     gene            2136..2717
                     /locus_tag="TV186_001436"
     CDS             2136..2717
                     /locus_tag="TV186_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1532821.1"
                     /translation="MNIEEAIKYFEDKRKDYIVSPSVIHVSTVEVINILKQIKLDKPK
                     PEIPQFVADWIEGHKADYITWEKADKADFVFRCINDLFNFGADMHTYDFDVSYEISKW
                     TQEHAYGFIVAVLFGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFSEIIDT
                     DFYSREDVRLTESEIRKDFDWAWERGFAKGVKE"
     gene            2714..2881
                     /locus_tag="TV186_001437"
     CDS             2714..2881
                     /locus_tag="TV186_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532822.1"
                     /translation="MNKSEIKNLVDRLSDLIDKCENDFEAMVFNPDGTFDLLLASHSA
                     LSKVLRGEVTE"
     gene            2878..3093
                     /locus_tag="TV186_001438"
     CDS             2878..3093
                     /locus_tag="TV186_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532823.1"
                     /translation="MKSYQKRFVEEYRQLTQRLSKLDKMLKKYAQGTLGFEPDCPIRL
                     LQEQRRVMSEYVDILEARAKFEGVDLE"
     gene            3167..3604
                     /locus_tag="TV186_001439"
     CDS             3167..3604
                     /locus_tag="TV186_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEL1532824.1"
                     /translation="MGNIPTPKANNFLEELKTIPDLIETLERDANLMSRSLIKSPQWS
                     DMRVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
     gene            complement(4109..4486)
                     /locus_tag="TV186_001440"
     CDS             complement(4109..4486)
                     /locus_tag="TV186_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL1532825.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(4538..4723)
                     /locus_tag="TV186_001441"
     CDS             complement(4538..4723)
                     /locus_tag="TV186_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL1532826.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            4839..5174
                     /locus_tag="TV186_001442"
     CDS             4839..5174
                     /locus_tag="TV186_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1532827.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            5337..5804
                     /locus_tag="TV186_001443"
     CDS             5337..5804
                     /locus_tag="TV186_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL1532828.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            5819..7573
                     /locus_tag="TV186_001444"
     CDS             5819..7573
                     /locus_tag="TV186_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1532829.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKMVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            7570..7740
                     /locus_tag="TV186_001445"
     CDS             7570..7740
                     /locus_tag="TV186_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532830.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            7733..7999
                     /locus_tag="TV186_001446"
     CDS             7733..7999
                     /locus_tag="TV186_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532831.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEVLRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            8033..9253
                     /locus_tag="TV186_001447"
     CDS             8033..9253
                     /locus_tag="TV186_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1532832.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAYISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            9231..9896
                     /locus_tag="TV186_001448"
     CDS             9231..9896
                     /locus_tag="TV186_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL1532833.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            9921..11108
                     /locus_tag="TV186_001449"
     CDS             9921..11108
                     /locus_tag="TV186_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL1532834.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASVEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEGLRFEGKDEVLIPLNQTTPVDPKTDGVKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKESGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQTLDTLKDKNGRYLLQDSITSASGKVFLGKPVFVLSDDVIGED
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            11253..11555
                     /locus_tag="TV186_001450"
     CDS             11253..11555
                     /locus_tag="TV186_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1532835.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            11552..11899
                     /locus_tag="TV186_001451"
     CDS             11552..11899
                     /locus_tag="TV186_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL1532836.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            11896..12273
                     /locus_tag="TV186_001452"
     CDS             11896..12273
                     /locus_tag="TV186_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1532837.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            12270..12740
                     /locus_tag="TV186_001453"
     CDS             12270..12740
                     /locus_tag="TV186_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532838.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLMNVRKYRYFDFYLKERGKNGKSKIWTT"
     gene            12712..13302
                     /locus_tag="TV186_001454"
     CDS             12712..13302
                     /locus_tag="TV186_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1532839.1"
                     /translation="MGKVKFGLRDFQYAVLGEDDNVATKKGGIKKLPGMKSAKLDITN
                     ELVTVSADDGPYVVLSGGITETKLEIEVLDLTTDARKDFFGIKVAAGVEKYNKNLTPN
                     NVACIFRTSDENGKAIWVGLLKGKFNLPGMETQTKEGSPNPKADTVTGNFVSRGTDGD
                     VLVIGREESHEFNYEAFAGFVFAGATDIKKGENFEM"
     gene            13354..13680
                     /locus_tag="TV186_001455"
     CDS             13354..13680
                     /locus_tag="TV186_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532840.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            13728..13877
                     /locus_tag="TV186_001456"
     CDS             13728..13877
                     /locus_tag="TV186_001456"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532841.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            13890..17813
                     /locus_tag="TV186_001457"
     CDS             13890..17813
                     /locus_tag="TV186_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1532842.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRALATETSVFTRFGKAAEKIGGKMKSLGDSVAGVGAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGIKTGDILSFSRTMIDLGESTNLSAEEAASSIAKIANITGLTSKEY
                     SRFGSSVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQTLSAIETAVINGGEDLTKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDELGLSGIRQSNMLKSLGLASETLGKALGISNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIIKWGLIAAAAGPALSIFGKGVGIIGSTIQGIGKMSQGLGALSGWLRTFKTGA
                     AAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGTAVSATEANALSNFKKKVDETNTSLQMFEAGAGSVKKVTEAFDDLVGSIEKLAQSK
                     LDKNINLAKKLGLSEETINALKSKTESVVNNVKSMNTQIKAIMEKHNGDMSQLSSAEK
                     ELVLRNQREMITAQLDLMKFSASEKKALTAALNNELDALNARQLEKVSENTVKMLDKE
                     NSAYKTKKAELKEILKQFGSDTSKLSAEELAARQEVLNRLTELNMQHNLKTKALNDQY
                     LAIQRERVQRLKESGKSQEEIHQGISQMASDMAQKLGISYDDAYRKLAYYTEKSGETL
                     KVLSRNTANATAEVAAANAQWDSLFTSDNPQQSLNELLSTAEGWNSFEIMVKNADVEP
                     TGRAALAEMLVAGGQWENMTLEQKKLVVDGQQAMIEIFDSKELLAQWQALTPEEKVLL
                     AKNLTQEPTMSAQQALDSVKQTVPADVNASDKTAGETQSAQNKIDNVKQRVPADVKAS
                     DKTGPDVASADRAVNSPKQKSPAVIRAQDNASGVAEGVIGALARIPRSVTTTITTFVR
                     KIFGHEKGTDFHPGGLAMVNDQKGPLYKELVTLPTGESFIPSGRNVILPLPRGSKVLK
                     ASRTKQLFPHYASGIGFDDTKIASLTTRLKSVQDKGQVIINTDPQLAELIKLLKDRDD
                     RNVTNNYTVNATNSSSSEDMFSQENMRRLLRELAYYTNGEGGRLA"
     gene            17813..18520
                     /locus_tag="TV186_001458"
     CDS             17813..18520
                     /locus_tag="TV186_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1532843.1"
                     /translation="MRYIEFNGTKSNDLGLLLERERSIKSTNNDIDLIEVAGRDGVLI
                     KDNERLKAVEQDFPFSLVGDVTVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQAKPILKIKGTGN
                     GVLTINDFETGLENVQGELVIDMERHLVYKDVLSAWDNIVRTEHHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            18517..>19997
                     /locus_tag="TV186_001459"
     CDS             18517..>19997
                     /locus_tag="TV186_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1532844.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKATRERNGNYSLYIKYP
                     LDGAFAHLFKEEMKIKSDAGRRTKWQTFEINRVLRNSKEHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKTPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEHEKPEEQLVTLPEFIIDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQQQIDKRNQR"
BASE COUNT         6794 a         3288 c         4533 g         5382 t
ORIGIN      
        1 acttacgcgg ttactgataa aagattgttt agggagcatg agttcgcaac aaaaagagaa
       61 gcgatgcagt ttattagaga gctagagtta gctaatgata agcgagcgac agaatattat
      121 ttgagagagt ggagagatgc taatggaaga tacgtttaaa aaaattaagg agcttgaagc
      181 tgcttgtcag gataggacag ataacattaa aaagccatca cactatcaag ggcggcatgg
      241 catggaagca atcgacgtgg ttaaaaactt cgcagcttgc ccagagcacg aggagggttt
      301 ttattggggc aatgctgtta agtacctttt gcggtatcac gctaaaaatg gtgttgaaga
      361 ccttaaaaaa gcacgtcaga accttgattg gttaatcgag aagttggagg aagtggaatg
      421 ataccaaaat ttagagtgtg gaagaatgag ttttagatta tcttgggaaa ttaacggcca
      481 aaccgttgag gttataggtg actataaaac actaaaagca gcctatgact caattaaggt
      541 ccacgtcaaa gacagagata aatttgccag cccatattat cgcatatggc aaaaaggagc
      601 tgtacacttt gtggattatg gaaaacacaa tgctttttat aagattgagg agaggtgatt
      661 aaatgatgga tacagaaaca ctagaagcag tatatgatgc tttgcagcta tccttgccaa
      721 aaataatcga tatgcttaaa gcagcatccg cgaccagaga tgatgcttac aaagagggtg
      781 tactcgatgg cgcggatttg atagctgata ctgtaataaa agctatcgga caaatgatcg
      841 atccggaggc tgatcatggc taaagacgac tttttaacag gttttgtact tacactttta
      901 gctgcttgcg tttttgcagc aggatttgtg attggatctg actgtagtag cgagcactac
      961 gagcaacaaa tgacagactt gcgtatgcag cttgttagca cgcagcagca gcttaagcaa
     1021 tctcgtgagc aaaaccagag acagactaaa cggattgcgg aattgacagg aaatggggga
     1081 taaaaaacac tacatggaaa taaaatgtgg aaattgctta caattactaa cagagttaac
     1141 tgatggatca atcgatatgg tgataacaga cccaccatac aacatatcag taaaaaataa
     1201 ctttgctaca atggggcgga caggtataga ttttggtgat tgggataaag gcttcgactt
     1261 gttaagttgg attgatattg caagtcgaaa attaactaaa aatggtggaa tggtgatctt
     1321 caacgattgg aaaaatttag gagatattgc aagacattgc gaaaagacag ggttagtagt
     1381 aaaagatatt tttcgttggg tcaaagataa ccctatgccc agaaacagag atagaaggta
     1441 tattacagac agcgagtacg ggatatgggt cgtccgaaaa aattccaagt gggtatttaa
     1501 tcggaaatcg gaaaaatatg ataggccgga atacagatat ccaattgtag ccggactgga
     1561 aaaaacacag caccctactc aaaagccagt agccctgatg agggacatca ttacgcgaca
     1621 cacaacaaaa ggggctgttg ttttagaccc ttttatgggt agcgggtcaa ctggagtagc
     1681 ttgtctactg acggagagag actttattgg atatgagcta aataaagatt actttaatat
     1741 cgcaaaaaaa aggatagcag aattaactgg gaatggggga tgaaatatgc cagaattgat
     1801 taacacagcc gacttacaga caccgataga agcactagaa aataacctag atttttttaa
     1861 aagtttttac aacgacgaac gctttgaaga tatggaaaat gcaaaaaaat tgattgagag
     1921 atacgaaaaa gctatatcaa ttttaaccga ggtacaaaat gaaagttaaa gatttacata
     1981 aagtgttagc taaagttgac cctgaacttg aagtttggat aaatgaaaaa gatggagggg
     2041 ttataactaa agctaaaaac gtgatgactt ggaatgagca tccaaataag ttttttataa
     2101 atgcagaaac acaataatgt taaccgaggt acaaaatgaa catcgaagaa gcgataaagt
     2161 attttgaaga taagagaaaa gattatattg tatcaccaag tgtaatacat gtatcgactg
     2221 ttgaggtcat aaatatttta aaacaaatta agttagataa accaaagcca gaaattccgc
     2281 agtttgtcgc tgattggata gagggacaca aagcagatta tattacgtgg gaaaaagctg
     2341 ataaagcaga ttttgttttt aggtgtatta atgacctctt taatttcggt gcagatatgc
     2401 atacctatga ctttgatgtg tcttatgaga tatcaaaatg gacgcaagaa catgcctacg
     2461 gttttattgt tgctgttttg ttcggctaca caataaaaaa agaaaagctg tatattgttg
     2521 agatccctaa tcctaatagt ggcatagaac acaaacatat tgcactagca aggttagcga
     2581 atggaaaact tggattttca gagatcatag atactgattt ttattcaaga gaagatgtcc
     2641 gactcaccga gtcagaaatc cgcaaagatt ttgattgggc ttgggaacga ggttttgcga
     2701 aaggtgtgaa ggaatgaata aaagcgaaat caaaaattta gtagatagac taagtgattt
     2761 aattgataaa tgcgagaacg actttgaggc aatggtattt aacccagacg gaacgtttga
     2821 cttattactc gcaagccatt ctgcgttgtc aaaagtgtta agaggagagg taacagaatg
     2881 aaatcatatc aaaaaagatt tgttgaagag tacagacaac ttacacaacg tttgtcaaag
     2941 ctagataaaa tgcttaaaaa atatgctcaa ggcactcttg gttttgaacc agattgccct
     3001 atcaggctat tacaggagca gagacgtgtg atgtcggagt atgtcgacat attggaagca
     3061 agagcaaaat ttgaaggggt tgatttggag taataaaaaa agacgtccat gcgaacgcct
     3121 tcatgattaa atacccaaca atattatatc atgaatggag agttagatgg gcaacattcc
     3181 gacaccaaaa gctaataatt ttttggaaga attaaagact atccccgatc ttatagagac
     3241 ccttgaaaga gacgctaacc taatgagtcg gtcgctcatt aagtctcctc aatggtctga
     3301 tatgcgagtg tctggtgggg tcaaacaatc acaggaagac aaaaacataa aaatgttaca
     3361 catggtcagt tattacagtg atcagattga gcggctaaaa gaccgtcggc aagaaatggc
     3421 taatttgatt gtgcaaagca tgggaatttg tgagagccat gttttgctaa cgacttatct
     3481 tgactgtgat ggagactacg agagagccag agaacgctta aacataggta atcggaataa
     3541 atactttatg tttgttaggc gaggaaagga aagtctagaa ttgatactaa aaaatactaa
     3601 ttagatacaa attgatacta cataatacta ataaccatgt tattatagta ctgttgaaat
     3661 aacaagaaga gataaccatt ttaccaattg actatttatt tagtcgctga ctttaactac
     3721 gatcaaactt gttattttac taaagcttag tagctttgcg ttaaaggtgt taaattactc
     3781 ggttgaaccg gtcgggtaag tcgcaaatat gaagagagtt gttgagacgt aaggaaatgt
     3841 catgtgcacg catcttatga tattgcaggt tcgaaccctg ccgtctcaat cagcgtcggg
     3901 gagacgcgac cccatacccc tttaaaggca gacacgttct gatgtgtggg tttttatgat
     3961 taaccgcaag tccaaaacca agggtcgcaa ccttgcttgt ggttagtagg gacaacggtt
     4021 gtaagtcggt tcgattccga ctgttcctgt gctagtcatc acatcgtgat ggctttttat
     4081 tatgcaaaaa agaaccacta agtggctctt atgcttgtag ttttaattca agtgcctctg
     4141 tgaggacttg cgagaaattg agattttcat cttcggctgc tttgtttaac cactcaggga
     4201 tagtcacgtt cttacgtact tttttagagt ggtatttttt catgtaggca atcatatcga
     4261 tgccgattaa agcaatatca gaatcacgat actgttcttt taagtcggaa acggagctag
     4321 cctttggata gtcagtatag tcttcaagag caaagcctaa gacttcgaca gccatttcgt
     4381 aagcttcttg aaagtcttta ccttgagtaa ttgcttcagg tacatctgga aatgtaacca
     4441 tgatatagtc tgtgtcttgt gtgaatgtag ctggatagat taacataatg attctccttc
     4501 gatcactgtg agataagcaa accatctggc aagcggatta ttttaaaccc gcctgcttta
     4561 gaatggtatc ttcaaggcct tttccgaggt ctttgttgtg tagaggaaca atggtttgat
     4621 gtccgttatt atctcggaat tttttgtgac ttccgttttg actgacttca tagaacccat
     4681 tcttttttag cagttttatc atctgctttg gggtcattgg catattgctt acctcacttt
     4741 ctatacttat attatacacg caataaacat ggttgtcaat aggtatgcgc aaaaaatgcg
     4801 tatttttgtt ttctattttt tattatggag gttagggtat gaggccgcag aagttaacaa
     4861 ttgcgggtgg cagacgaacg actgttgact acgatgatag gtcagctgag tatcgtgact
     4921 ataatcgtaa cagatggaag tatgatagga agactaagca gttttataac tctaagattt
     4981 ggagagagac aagtaagcaa gtcttattgc aaagtgatta tatctgtgca atgtgtggtg
     5041 gagaagcaac gatgactgat cacattgtct cagttaagaa agattggaat aaaagattag
     5101 attggaataa cttgcaagca agttgtaaag cttgtaacga ttgtaaagca ataagagaga
     5161 gacggaaaac ctaaacgtac ataaaaagta acatacgcaa tcattgttcg ggaaataccc
     5221 cgcctatttt ttaacggggc tatattgttc ggaaacttaa gaacgcgccc ttttctgtgc
     5281 aaaaaaatcc ctttttgaaa tttttgaaac tgtaaagttt gtgtaaagga ggtcttatgg
     5341 gaagaaattt aaagctagtt gaaacgacaa aaaagcatct tacgaaagaa gaaaaaatag
     5401 tgcgagaaac cgcgcaaaat aaggcgtctg acggtcttaa aaagttgcaa aagacacctc
     5461 ctgaacactt taataatgta gctaagtacg agtataggag aatcatagaa gacctccaaa
     5521 acctacccct aagaaatctc gatagagggc tattagagtt atattgcaca tggtatgcta
     5581 tctacaaaga aacaagtaga aaactagatg aggttggtta ttttacgaat gatccagaca
     5641 aaggcattat tcctagtccg cttattttaa cattggaaaa agccactgcg aatattagaa
     5701 gtagtgccag tcaattagga ctaacggtag atagtcgcat gaagatgttt attccgaagg
     5761 aagaagaaaa acctaagagt atatttgata aatttggagg atagagagaa agggggtcat
     5821 gacaatagaa tacgattatt cagcaatcgg cgacatctat aaagatgacg ctttttatta
     5881 tgcaaaaatg gtcgttgatg aagagattaa agcaagtaag aaggtcttta aagcttgtct
     5941 aagacatttg aatgacctta aaaaaataga tgatgataat tttaaattta tctatttacc
     6001 aaaaaaagca attgacccca taatttttat tgagctattg ccagacgtta agacgggaaa
     6061 gccttatcct ttagcgatgt ttcagaagtt tattatcggg aatttatacg gatggcgaaa
     6121 gaaaacagat cattccttaa gacgctttag aaaagctatg atttcggttg ctcgtaaaaa
     6181 tggcaaaaca attctgatag ctggtatctt gctttatgaa tttttgtttg ggcataatcc
     6241 atctatgagt agacaattgt tttgtacagc taatgaccgt acacaggcta aaattgcttg
     6301 ggacatggca aagaagcaac tctcatcttt aagagcaaag gacgctgatg tcagaaaagc
     6361 cacgaaaatt gttcgtgatg agctgaaaaa cttacatgat gaatcttata ttagggctct
     6421 tagtcgagat actggggcag tcgatgggtt cgagccttac gttggcgttt tagatgagtt
     6481 tgcggcatca aagacaaacg aaatgttaga gcttttagaa tccggtcaag gtcagcttga
     6541 taatccgttt atcttgatta tctcaacagc tggtatggat ttgaatgtcc ccatgcacac
     6601 aattgagtat ccgtacatca ctaaaatttt agacgaagaa attgtagatg atggctattt
     6661 tggatatgtc gcagagcaag acaacgaagg tgaaattaaa gatgaatcaa attggataaa
     6721 atcaaatcca atcctcgagg ttgaagcttt gcacgataag ctaatggatt acctgagaac
     6781 gcgtcgtaga gtgtctcttg aaacaggtga aattaacaag gtacttatca aaaactttaa
     6841 catgtggcgg cagtcgagtg aggaatcata tattgataag caatcttggg aacttgctcg
     6901 tattgataaa cccgacacac ataaacgaag ggtctggcta ggtgtggacg tcggtcgtgt
     6961 tagtgactta tttgctatta caccagttat tatgatggac gatttttggt atattgacag
     7021 tttttctttt gttgcgacaa agtatgggtt aacggctaaa gaaaagcgtg atggtgtgtc
     7081 ttacagtaat ttagaacgtc aaggctattg cgagataaca acattagaaa gtggggttat
     7141 tgatgatgag agagttttag aaaaaataga ggagatggtc tattcgaatg actgggaagt
     7201 taacggaatc tgttttgacc cttaccaatt tggaacgctg cttacgatga ttgagaaaag
     7261 gcacccagaa tggcctctca tagaggtttc gcaaacgaca atggttttga acatgccaac
     7321 aaagcaattt cgtgatgatc tcaagaatgg caaaataaag cactctggca atccattgct
     7381 aacaatggct gttaataacg cttatatcaa gactgataac aatggcatga ggattgataa
     7441 gaataagaat agcaataaga tagaccctct ggacgctgct ttagacgggt atgcagtttg
     7501 ttacttagag ccatttgacg gctctggtta ctggacaagt gagaaaattt taggaggaga
     7561 gacactgttt tgattggttt tattttaaaa aacatacata cattaatctt gttagctgga
     7621 ctaggtttat tgatgtatgg gttgtttttg tttggtgata aagttggttt tatcgctagt
     7681 ggtcttattt taattttttt agctatctat gtagatagcg taggaggaaa acatgaataa
     7741 acgcattaag aaaaaacgta aattggaaac agcggttgtg atgcttgttg cagaaaatgc
     7801 tatgcaagct gaagtactca ggaatcaaaa cagacaaatt gcagagctga gatcgattat
     7861 acaacaaaac gcccaagcga caaatagaga gtttgcagca gttaaatcag cgacgctaga
     7921 caaccaagca gccattaaga aaattgggga tgaggtttat tatatcaagc aaaattataa
     7981 gcgcaagtgg cggaaataga tgttaatggt ttagaaagga ggtgagaaat cgatgagttt
     8041 ttttcaacct ttgggcagtt caaaggtgtc ctatgatgac tatgtatcat ctgttttagc
     8101 tggcgatgtc tcccaaaaat acttaggagt gtcggctttg aagaatagcg atattttaac
     8161 agcaacgtct attatagctg gggatattgc taggtttccg cttgttaaaa aggatgttaa
     8221 tggggacatt atccatgatg aggatattaa ttatctttta aatgttaaat ccacaaaaaa
     8281 tgcgagcgct aggacctgga agtttgctat ggcagtaaat gccattttga ctggtaattc
     8341 tttttcgcgt attttgagag atccaaagac taaccaagct ttgcaattcc aattttacag
     8401 gccgtcagaa acgactgttg aggagacaga taaccacgag atagtttata cgtttactga
     8461 tatgttgaca gcaaaacagg ttaaatgttt tgcccatgac gttatccact ggaagttttt
     8521 tagtcacgat acaattttgg gaaggtcccc gctactgtct ttaggtgatg agattgattt
     8581 gcaaaccggc ggcatcaata ccttaattaa attcttcaaa gatggttttt ctagtggcat
     8641 cttaaaaatg aaaggcgctt atataagcgg tgaagcacgt aagagagcca gagttgaatt
     8701 tgaaaaaatg cgcgagggtg caattggtgg tagtccttta gtattcgacg atacgcaaga
     8761 atacacgccg cttgaaatcg atactaacgt attgcaatta attacaagta acaatttttc
     8821 aacggcgcaa atcgcaaaag ctttgcgggt tcccagctac aagcttggtg ttaatagtcc
     8881 aaatcaatct gttgcccagt tgatggaaga ttatgtcacg aatgatttgc cattttattt
     8941 tgatgctatc acaagtgagt taggacttaa gacgctaagt gataaggata ggcgtttgta
     9001 tcgtatcgag tttgatacac gaagcgtcac aggtcgcaat gttgatgaga ttgtcaaatt
     9061 ggttaataac caaatcttga cgcctaacca aggcctcgta gagcttggta agcaaaaatc
     9121 aacagatcca aacatggata ggtaccagtc tagtctaaac tacgtctttt tagacaaaaa
     9181 agaagaatat caagacaagg ttggtatcaa agggaaagga ggtgaggtaa atgccaaaga
     9241 ggataaatct taaaggacca ctaattgcaa ataactctca agaagtttac gactattacg
     9301 gaatggaagc agcaagtgct aaaagtatca ttgagcaatt tcctgaagat aatagcgata
     9361 ttgttttgga agttaattca aacggtggac ttgtgacagt tgggagtgaa atctataccg
     9421 ctttacgaaa ttacaaagga aaagtaactg cagaaattac tggcatggct gcaagtgcag
     9481 catctgtggc tgttatgggt gcggataagg ttgtcatgag tcctacagct caaatgatgg
     9541 tgcataaagc actctttaaa tgggtgtctg gtaatagtga tgacctagac aaagcttcta
     9601 atgccttaaa atcaagtgat aaagctattg tgagtgccta tgtcgcaaaa acagggttat
     9661 cagaagatgc aatcatggat ttaatgcgaa atgaaacgtt tatgtccgct caagatgccg
     9721 tagaaaaagg ttttgcggac gaagttatgt cttttgaagc agttgctagc attgataatt
     9781 ccatgttgcc gcaagctgtt attgatgact attacagaag taggaacaaa cgaaaacaag
     9841 agattagcaa catgttacta gaaattgaaa aagaagaaat tttacgaggg ctataagctc
     9901 tttttttatt ggaggaattt atgttcgaag aaaaaatcaa agaaattaaa gcgaatatcg
     9961 ctaatttaaa ccaagctatt gctactaaaa caacagaagt aaaaaatgct ttggaatcag
    10021 atgaccttga aactgctcgc tcaattaaag cagaaattga agaagctaaa gcaaacctag
    10081 cagaagcaga aaatgacttg aaattgtatg aagctagcgt tgaaaaaggc ggtgcagaaa
    10141 atactggagg aaaagaagtg ccacaagaaa ctaaaacata tcgcgaaagc gttaacgaat
    10201 ttattcgttc aaaaggaaca gtaaccaacg aaggtttgcg ttttgaaggg aaagacgagg
    10261 ttcttatccc acttaaccaa acaacgcctg tagaccctaa aacggatggt gttaagaaaa
    10321 cggatgtaaa acctgtctct agtgaagaaa ttctttacac accagcgcgt gaagtcaaga
    10381 cagttgttga tttgaaacaa ttcactagca tccacccagc taaaaaagaa tcagggaaat
    10441 ggccagtatt gcaacgtgct acagaaaaaa tggttagcgt tgaagaattg gaaaaaaatc
    10501 caaaactagg caaaccacaa tttaaaaacg ttgaatggga agttaagact tatcgtggag
    10561 ctatcccact gtctcaagaa tctatcgatg atgcagatgt agatttggtt ggtattgttg
    10621 ctgaaacaat cggtcaaatg aaagttaata caactaatga tgcaattgct aaagtcctaa
    10681 aaacatttga ggctaaagct ggtgtcaaaa cattagatga catcaaaaaa atcctaaatg
    10741 tagatttaga tccagcttac aatgtatcat ttattgtatc tcaaagtttc tatcaaaccc
    10801 tagatacttt aaaagacaaa aatggtcgct acttgcttca agactcaatc acctctgcgt
    10861 ctggcaaagt gttccttgga aaaccagtat ttgtcctatc tgatgacgtg attggcgaag
    10921 actcagcttt tgtcggagat tttaagcgag gcgtgttatt cgctgatcgt aaagatttag
    10981 ggcttcgttg ggcagataac gaaatttacg gtcaatactt gcaagctgtc cttcgctttg
    11041 gtgtcgctaa ggtagatgac aaagctggat actatgtgac attcaaacca gaacaattgc
    11101 cctcataagg ccactgaaga agtggcgaaa ccaactagca aaagcactgt cgaggagatt
    11161 aagcgctatt taacaagcaa gggaattgac tttaatggga aaacattaaa atctgattta
    11221 ttaaaacttg caggcgttga agaggtatag ctatggctgt atcaaaagag ttattagaca
    11281 gtgtaaaact ctattgtaaa attgactttg attttgatga cgacatcatc aaagaaatga
    11341 ttgaatctgc tcaagaacaa atctgttttg caatagaaga cggttctact cctgaaaagt
    11401 tcaaaggtca cgctaaattt aatttagctg tcaaaaagca agtcaaggaa gagtatgacc
    11461 atcgcggttt gtctgcggat agttttcgct atccgttggc aaatggtgtt ttaaacatta
    11521 tccatcaatt gcgattgaga ggtgatgatt cgtgattaca cgcaagatga acgtcaggat
    11581 aacgattttt agccaatcag gcgggcaaaa tgaagatggt gaagtagtat ctgctgtcag
    11641 aaaggacttg tatacttgtt gggcagaagt gctaaaaacg cagttgagag attttaatta
    11701 tcaatcaaag tatcaaaacg ctagcaattt gccaacaaat aaggatacta aggttttttt
    11761 aattaggtat aaccctgaat tatctataga taacacgatg tttgttgagt ttggcaagcg
    11821 catttataag atagataaaa tcgaatctga cgaatctggc aaagatatta tcatgataag
    11881 tggagtaagc atgtcatgac aaaaggttta gatgaaatat tggctaatct gacaaagctt
    11941 gaagtaaaag caccaaaaac cgcaaaagca gcagtaactg aagttgccaa agaatttgaa
    12001 aaagcactta aagcaaatac ccctgtttat gagattgaaa cagatgagcg gctacaggaa
    12061 gataccgtta tcagtggttt taaaggagct aatgttggaa ttgtatccaa ggaaatcggc
    12121 tatggcaaag cgactggttg gcgtgcgcac tatcctaacg atgggaccat ttaccaacgc
    12181 ggacaagact ttaaggaaaa aactatcaat cagatgacac caaaagctaa acaaatctac
    12241 gcagcaaaag ttaaggaggg actagggctt tgattgctga aacagcagct tataaattat
    12301 taagtaacga taagacgcta aatgagttgt tggataggct cagaggcggt ccttttaaaa
    12361 atgggtttaa gcaaggcata tttacttatg atattccaga taacccagtt gacttgcgta
    12421 aggtagattt agcgcctttt atgcgaatca acacaacatt agacggtcct gctgattatg
    12481 cagatgatga gatactgtgt aacgagcaac ggatcaccat caatttttgg tgcaaaacag
    12541 cttctgaagc tgaccaaatt agcaaatgta tagatgatat tttaaaaaaa ggcggttttg
    12601 aaagatacac cgcaaacgaa aaaccaagat ataaagatag cgatattgac ttactcatga
    12661 acgtaaggaa ataccgctat tttgattttt atttaaaaga aagaggaaaa aatgggaaaa
    12721 gtaaaatttg gactacgtga ttttcagtac gccgtactag gcgaagatga taatgttgca
    12781 acgaaaaaag gtggtattaa aaaactacct ggaatgaaat ctgcaaaact cgatattacc
    12841 aatgaattgg ttaccgtttc ggcagatgat gggccttatg tagtgctttc gggaggaatc
    12901 accgaaacaa aactagaaat tgaagtactc gatcttacaa ccgatgcacg taaggacttt
    12961 ttcggcatta aagtggcggc aggtgttgaa aaatataaca aaaacttgac acctaataat
    13021 gtagcctgca tttttagaac aagtgatgag aacgggaagg ctatttgggt aggactgctt
    13081 aaaggtaaat ttaatttacc tggcatggaa actcaaacaa aagaaggatc tcctaacccc
    13141 aaagctgata ccgtaacagg taactttgtg tctcgtggca ccgatggaga cgtgcttgtt
    13201 attggaagag aagaaagtca tgaatttaat tatgaagctt ttgcaggatt tgtttttgct
    13261 ggtgcgacag atattaaaaa aggcgaaaac ttcgaaatgt aacaatcagg ttggatttta
    13321 aatccaacct tttatttttg ataaggagta gatatgtacg aaattacctt aaaaaaaggt
    13381 ggtgtagata aagttttttc aaaagacttt attaacgttg aggataattt gttggctgtt
    13441 gagcatcaag ttagacaaag cgctgtgttt agcgatgaga aaagacgctt agattctaaa
    13501 gcgcatagaa aacttaacga atcttacttg caaatgtttg ttgatatgta cgcaggtcaa
    13561 tttacagtcg atgatttaaa gcaatctgac atgagtgttt taaatacact taatgacctg
    13621 tacattgcag cactcggtgg agagcaagag gaagacgaaa gcgaaaaaaa ggaacaataa
    13681 ccccacaaga ggctaaagaa aacttactct tgtggataca gagccttttg aaaaacggtt
    13741 ataccatttt agatattaaa aaaatgcgct tatctgatat tgaattgatg gtacaagcgc
    13801 tagaaattga aactgtcgaa aaagaagaag tgattgaaac gaccttggat aaggcattcc
    13861 cattcctttt cggctagaaa ggaggctaaa tggggaatat aggtgattta gtagcaacgg
    13921 ctacactaga catatcacca tttatgtcaa acacaagaaa cctaaaaacc tacatgaaag
    13981 gcttagacaa ctcgttaaaa gctgttgaaa agagttttca agggcatggc gggcggatta
    14041 aaggtcttaa agcggtctat gctgaaacag gtagtgcatt aaaaggttac caagaattac
    14101 taaaaactca gtcacaaaaa tatagcgacc taaaaaaaga gataggcgat gttaataacg
    14161 ctactgctga gcaaaagcaa aaattgattg gcgctaaatc agccatgttg gagactgctg
    14221 cgaaagtcac agaattgcaa aacagattac gagcgttagc cactgaaact agcgttttta
    14281 caagatttgg taaagctgct gaaaaaatcg gcggcaagat gaaatcatta ggtgattctg
    14341 tagcaggagt tggtgctgca tttacgagag gagttaccgc tcctattgta gcgggcgctg
    14401 gttatgctat taaagcagct gttgactatg aaactgcgtt tgccggtgtt aaaaaaacag
    14461 ttgatgagac ggcgacagta tcctatgcta agttgtcgca aggcattagg caaatggcta
    14521 aagagttgcc agccagcgcg gtagaaatcg ctcacgttgc agaggcggca ggtcaattag
    14581 ggattaaaac aggtgatatc cttagttttt ctcgtacaat gattgattta ggagaatcca
    14641 ctaatctatc cgcagaagaa gctgcatcat ctattgcgaa aatcgcaaac attacaggac
    14701 taacgtcaaa ggaatattct agatttggta gctctgttgt tgccttaggt aataactttg
    14761 cgacaactga aagagatatt gttgcgatga caaaccgtat cgccgcatct ggtaaacttg
    14821 ccggcttaac taatcaagaa atgttagcgt tggcaactgc tatgtcaagc gtcggtatcg
    14881 aggcagaagc tggtggtact gctatgactc aaacattatc agcaattgaa actgctgtta
    14941 ttaatggtgg agaagattta acaaaatttg ctcaaattgc caatatgtca tccgctgatt
    15001 ttgcaagagc gtggaaagag aagccaattg ttgcattgca agagtttatt aaggggcttg
    15061 gtcaacttga taaaaaaggt gaaagtgcta caaaagtgct tgatgaactc ggtttaagtg
    15121 gtatccgcca gtctaacatg ttgaaatctt taggattagc atctgagact ttaggcaagg
    15181 ctcttggaat ctctaacaaa gcttggcaag aaaacactgc tttaactgac gaagctaata
    15241 agcgctatga gacaacagag tctaagctaa aaatgcttaa gaatgaagtt aatgatgtag
    15301 ctattgaatt tggtggccct ttggttgacg ctctaagaaa tgggctcgaa gcaggaaaac
    15361 caattattca aatggcagca gatttagcca agcaatttaa ctcgcttgac aaagagcaac
    15421 aacagcagat tatcaagtgg ggacttattg ctgccgccgc tggtccagct ttgtctatct
    15481 ttggtaaagg tgttggcatt attggcagta ctattcaagg cattgggaaa atgagtcaag
    15541 gtttaggagc gttgtcaggc tggttgcgca cttttaaaac tggagcggca gcagctagtg
    15601 caggagccga agctgccaca gcttctatgg gcggaatggc tggcgcggtt gccttattaa
    15661 gcaacccagt aacgtggggt gttttgctag gtggggcagc cattgtgggt ataggtttaa
    15721 ttgctgatag catgtataaa gcccaaaaac gcacagaaga gtggggaacc gctgtttccg
    15781 cgacagaagc aaatgcacta agtaacttta agaaaaaagt tgacgaaact aacacttcgt
    15841 tgcaaatgtt cgaggcaggc gcaggtagcg ttaagaaagt gactgaagct tttgatgatt
    15901 tggtcggaag tattgaaaag ttagctcaat caaaattaga taagaatata aacttagcta
    15961 aaaaattagg attatcagaa gaaaccataa atgctttgaa atccaaaact gaatcagtgg
    16021 ttaacaatgt taaaagcatg aatacccaga ttaaagcaat catggagaaa cacaacggtg
    16081 acatgagcca gttgtcaagc gctgaaaaag aacttgtttt gcgaaatcaa agagaaatga
    16141 ttaccgctca acttgattta atgaagttct ctgcatcaga aaagaaagct ttaacagcag
    16201 ctttgaataa cgaattagat gccctcaacg caagacagtt ggaaaaagta tccgaaaaca
    16261 ccgttaagat gcttgataaa gaaaattctg cttacaaaac aaaaaaagca gaattaaaag
    16321 aaattttaaa gcaatttgga agcgatacta gcaagctaag cgctgaagaa ttggctgcta
    16381 gacaggaagt tttgaataga cttactgagt taaatatgca gcacaaccta aaaaccaaag
    16441 ctttgaacga tcagtacctt gctatccaga gggagcgtgt ccaacggtta aaagaatctg
    16501 gcaagagtca agaagaaatc caccaaggga ttagccaaat ggcatcagac atggctcaga
    16561 agcttggtat tagctatgac gatgcttacc gtaaactagc ttattatact gagaaatctg
    16621 gtgaaacgtt gaaagttttg tcgcgtaata cggctaatgc tacggcggaa gtagcagcag
    16681 ctaacgctca gtgggatagc ttgtttacga gcgataatcc acaacaaagc ctaaacgaat
    16741 tgttatcgac cgcagaaggc tggaacagtt ttgaaatcat ggttaagaat gccgacgttg
    16801 aaccgacagg tagagccgca cttgctgaaa tgttggtagc tggtggccaa tgggaaaaca
    16861 tgacgttaga gcagaagaag ttggttgttg atggtcaaca agcgatgatt gaaatctttg
    16921 atagcaagga gttattagcg cagtggcaag cattgacgcc agaagaaaag gttttgctag
    16981 cgaaaaactt aacacaagaa ccaactatgt cggctcaaca agcccttgac agtgtcaagc
    17041 aaacagtacc tgctgatgtt aacgcaagtg ataaaacagc aggcgaaact caatcagcac
    17101 aaaacaagat tgacaatgtt aaacaacgag ttccagctga tgtgaaagca tcggataaga
    17161 ctggaccaga tgtagcaagt gctgacaggg ctgtcaatag tcctaaacaa aaaagtccag
    17221 ctgttatcag agcccaagat aatgctagcg gtgttgcaga aggtgttata ggtgcattgg
    17281 ctagaatccc aagaagtgtt acaacaacca ttacaacgtt tgtccgtaag atttttggac
    17341 atgaaaaagg gactgatttc caccccggcg ggttagctat ggtcaatgac caaaaagggc
    17401 cgctatacaa ggagttggtc actttaccaa cgggtgaatc atttattcca agcggacgaa
    17461 atgtcatcct ccctttgcca agggggtcta aagtcttaaa ggccagccgt acaaaacaat
    17521 tattcccgca ctatgccagc ggaataggtt ttgatgacac caaaatcgct agtctgacaa
    17581 ctcgtcttaa atctgtgcaa gataaggggc aagtgattat caataccgac cctcaacttg
    17641 cggagttaat taaactactt aaagacagag atgacagaaa tgtcacaaat aactataccg
    17701 taaacgctac taatagtagt agttcagagg atatgtttag ccaagaaaat atgagacggc
    17761 tactcagaga attagcttac tacacgaacg gagaaggagg gaggttagct taatgcgata
    17821 cattgaattt aatggcacta aaagcaatga tttaggttta ttgctagagc gcgaacgatc
    17881 aattaagtca acaaacaacg acattgattt aatcgaagta gcaggtcgtg acggtgtact
    17941 tattaaagac aacgaacgct taaaagcggt tgagcaagac tttccttttt cgctggttgg
    18001 tgacgtgact gtcaatcaac aaaaaataag cgaatggtta catgtcaagg gttggcacga
    18061 cttggcgttg tcttgggaca aggattatat ctatcgggct agtgttgtca atctttttga
    18121 aatagacgag atacttaagc aatttggtag attaaaagtt aatttcttaa tccaccctat
    18181 caaatattta aaaacaggta agcaagaggt gcctctcgta aatggaggta ctctacaaaa
    18241 tcctggcaat gtccaagcta aacctatctt aaaaatcaaa ggcacaggca atggtgtttt
    18301 aaccattaat gactttgaga caggacttga aaatgtacag ggcgagcttg ttatagatat
    18361 ggaaaggcat cttgtctata aggatgtttt atcggcttgg gataatatcg taaggacaga
    18421 acatcatcgc atgcctcttt ttgatattgg tcaaaacaaa atctcatgga ctggtaactt
    18481 tactatcacc gcagtgccaa actggggggt taaagtatga taccagtttt atacgaggcc
    18541 aaagaaacca aatttaggac ttttggcctt ggagaaattg cggacgctta cgaggttaaa
    18601 gctacacgtg agcgtaatgg caattactcg ttatatatca aatatccttt agatggtgcc
    18661 tttgctcatc tgttcaaaga agagatgaag attaagtccg atgctgggcg taggactaag
    18721 tggcagacgt ttgagattaa tcgggtgctg cggaatagta aagagcacat tgagattttt
    18781 gcacgccaca tatcgatgcg cacacaggac atcgctttaa aaccatttgt gagcgggtct
    18841 agcattgacg cagagtcggc actggaggtt tggcgggata atcttgtcgg tgatgatacc
    18901 tttgatgtta aaagcgacat tttaacacta ggcagcttta actgggaagt tgacaagata
    18961 ggcaatgcaa gaggcgctct cgggggtgtc gctggctcta tcttagatgt ttacggtggt
    19021 gagtacgagt ttgacaatcg cacaatcatc ttacataaac aaatggggcg taagacccct
    19081 acggttttgg agtatggccg caatatcgtt agcgtggaag aggagcgttt gcttgatggc
    19141 aattatacct caatctatcc ttacgtaaga tatacgccac aaccaaagcc gcaagaggaa
    19201 gcctctggta agccgcacat cggcgagcat gagaaacccg aagaacagct ggtcactttg
    19261 cctgaattta tcatagacgg tcagtatctt gacttatatg cccaacgcag aatacagatg
    19321 gttgatttat ctagtcattt taatgatgac aaaaaagagc caacagtcga agaaattaga
    19381 aagctggctc agaaatacct taaagataat aatgtaggcg cacctaaaat cagtatagag
    19441 gttgattata tcgacctgtc acagacgctt gactatcaag attttagagt tatggaggag
    19501 gtcgagcttt gcgatattgt accgctttac tatccaaagt ttggtatcac aaccgagacc
    19561 gaaaaagtcg ttgagattgt ctatgacgtc tatacagata gcaatcacac aataaagctt
    19621 ggcacgattg gccaatccat ctctaagagt ctgacaggtg gtgttacgca gcggattgag
    19681 acgctggaaa acaaccaaaa ggttattact aataatcaac agcaatttga gcttaattta
    19741 cccaaatacc tcaacgatct aaacggtacc aagatatggt acgaaaaacc agatgacaac
    19801 gttgagcaca agataggcga tttttggttt gagaaaaacg gtaaatatca gcgtacctgg
    19861 gtttgggacg ggaatcaatg ggtaaaaatc attgatactg aggatttaaa tcctaatcag
    19921 cgcgcttttg atgaggctat ggccgagatc gaaaagctta agcagcacca acaacaaatt
    19981 gacaaacgca atcagcg
//
LOCUS       DARYXZ010000042        19447 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYXZ010000042 DARYXZ010000000
VERSION     DARYXZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19447
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            1..240
                     /locus_tag="TV186_001460"
     CDS             1..240
                     /locus_tag="TV186_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1532845.1"
                     /translation="MDRKIKVMGIINSETEAFKLELNKKQVSEMLGVDPKTFDVRFNS
                     LKDFPRIETGGREKYPRDVVIEWYRKNWERTGIKA"
     gene            237..407
                     /locus_tag="TV186_001461"
     CDS             237..407
                     /locus_tag="TV186_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532846.1"
                     /translation="MTKLDLFLLITTLVLAIITSAQYKIIKNYNSAGNKRKIFEEVAL
                     ENSKKWSAERYD"
     gene            400..606
                     /locus_tag="TV186_001462"
     CDS             400..606
                     /locus_tag="TV186_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532847.1"
                     /translation="MTKQELQKQLLDIMAEFDSAVEALLDLNESGEISDQELLLNLKV
                     RYKSYSGEKICIIDKLIKLGGAER"
     gene            603..986
                     /locus_tag="TV186_001463"
     CDS             603..986
                     /locus_tag="TV186_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532848.1"
                     /translation="MTTFEKVISKLNRIEGELAKPESERRDNSYHLSALLGSIKQDLK
                     LMLWIELPSLNNVEKYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDRRN
                     FVKLAEKEFKGATLSWQEFLWGKKK"
     gene            983..1135
                     /locus_tag="TV186_001464"
     CDS             983..1135
                     /locus_tag="TV186_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532849.1"
                     /translation="MNISIKLIGETLAGLNDILRQGGLSCSQNQALADAVFILTALKQ
                     VIEERK"
     gene            1132..1335
                     /locus_tag="TV186_001465"
     CDS             1132..1335
                     /locus_tag="TV186_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532850.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            1423..1722
                     /locus_tag="TV186_001466"
     CDS             1423..1722
                     /locus_tag="TV186_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532851.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            1722..2879
                     /locus_tag="TV186_001467"
     CDS             1722..2879
                     /locus_tag="TV186_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL1532852.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKTFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNIVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGALEKLIGKTTFADLLAEVIDKPQGKPVLVPEKDKRPAINSLEQAIKDFE"
     gene            2893..3456
                     /locus_tag="TV186_001468"
     CDS             2893..3456
                     /locus_tag="TV186_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL1532853.1"
                     /translation="MTTTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHMFMS
                     ISSKTKPQIIDKYKNSVDSAEEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            3499..5421
                     /locus_tag="TV186_001469"
     CDS             3499..5421
                     /locus_tag="TV186_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEL1532854.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPCQWQCTMVLA
                     QELGLPSSLEKCALYLKLAQEKDTSGKNLIRYFSLPCKPSKTNGGRTRNLPEHAPEKW
                     QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKAITGLANPNSRAQLLPWLKEHGYSANGLTKADVEQELKTAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGCTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKL
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDKAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGYGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAEG
                     LPLNSEGYVTKYYMKD"
     gene            5426..7810
                     /locus_tag="TV186_001470"
     CDS             5426..7810
                     /locus_tag="TV186_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1532855.1"
                     /translation="MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWHDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTDGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSK
                     AMNAFVCDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETIVAIKAQA
                     FSSEVFTESDLNKIVLVNGVYDLRDNSFKTKFDPELHARSSHPVAYAPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRNALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLARNSFTQRMNELNFENKNAKMGGKTVRCWIGFRIKGEF"
     gene            8171..8446
                     /locus_tag="TV186_001471"
     CDS             8171..8446
                     /locus_tag="TV186_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL1532856.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFTSPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDMALKEMENWV"
     gene            8443..9765
                     /locus_tag="TV186_001472"
     CDS             8443..9765
                     /locus_tag="TV186_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1532857.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIEKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPIVYSWTLRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLVN
                     KLLQMANGAIYDADKTTVAIHDDKLDALEDIVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGRIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            9766..9933
                     /locus_tag="TV186_001473"
     CDS             9766..9933
                     /locus_tag="TV186_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532858.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAA
                     VKEKYTREWKK"
     gene            9930..10103
                     /locus_tag="TV186_001474"
     CDS             9930..10103
                     /locus_tag="TV186_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532859.1"
                     /translation="MTKQELIEEIEDEINDIDLLIDDYQYEIDELERDIDELDTQKDI
                     LKRKLDNLLESVE"
     gene            10103..10372
                     /locus_tag="TV186_001475"
     CDS             10103..10372
                     /locus_tag="TV186_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532860.1"
                     /translation="MTEQQMIDCLLYELAKKDKAIKNKSIIIAVLTAVLCLVSVLSIA
                     LQNHYEPQITGLQSQLRRTQYQLKRASEDRARQTKRIAELTGNGG"
     gene            10575..10991
                     /locus_tag="TV186_001476"
     CDS             10575..10991
                     /locus_tag="TV186_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL1532861.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            11081..11533
                     /locus_tag="TV186_001477"
     CDS             11081..11533
                     /locus_tag="TV186_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1532862.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            11523..12800
                     /locus_tag="TV186_001478"
     CDS             11523..12800
                     /locus_tag="TV186_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1532863.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAD
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLSSFFGLDYGFINDPSAFLHV
                     KIDDANKKLYVIEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWVVDERCVKTIEELENYTWKKDKKTNEYINEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            12816..14348
                     /locus_tag="TV186_001479"
     CDS             12816..14348
                     /locus_tag="TV186_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1532864.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEEIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKVYTSDTIYTYEDYN
                     LETKGTCLKEHEEHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            14308..15753
                     /locus_tag="TV186_001480"
     CDS             14308..15753
                     /locus_tag="TV186_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1532865.1"
                     /translation="MLVVKKNQQQKSLNYWQKRQEDILSYLDRADLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYCAGILKGVLDSAFENHLKKAASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKKLKQGFVRGEHPRAIARDLAKQ
                     FNVANHRAETLIRTDGTMVINNATARRYLDAGLKYYRDLVRLDDRTTEICRKIAKENK
                     RKLLSELKPGINAAPYHFSCRTTLIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNG
                     HKPQLSLLNEYVKNGTPYKVDGHNVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HINTPDYLVDGVPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEQIYMIDRRGLDISIIKNKDEVLAVLEKEG"
     gene            15784..15972
                     /locus_tag="TV186_001481"
     CDS             15784..15972
                     /locus_tag="TV186_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532866.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKVG"
     gene            15975..16241
                     /locus_tag="TV186_001482"
     CDS             15975..16241
                     /locus_tag="TV186_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532867.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQAAITNIAIDVNYIKKNYKRKWGK"
     gene            16397..16966
                     /locus_tag="TV186_001483"
     CDS             16397..16966
                     /locus_tag="TV186_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1532868.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAE
                     RTKWESEQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKTNIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            16979..17866
                     /locus_tag="TV186_001484"
     CDS             16979..17866
                     /locus_tag="TV186_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1532869.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            17878..18234
                     /locus_tag="TV186_001485"
     CDS             17878..18234
                     /locus_tag="TV186_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1532870.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAISESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGTVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            18245..18523
                     /locus_tag="TV186_001486"
     CDS             18245..18523
                     /locus_tag="TV186_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532871.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKPRLIKGLAHHKNSTVIYV"
     gene            18520..18864
                     /locus_tag="TV186_001487"
     CDS             18520..18864
                     /locus_tag="TV186_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1532872.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYNEQQQLLHYRVVSPALYSVYIELGTRKMEAQPFLDPALRKEWP
                     VLMANLKKMFKR"
     gene            18868..19227
                     /locus_tag="TV186_001488"
     CDS             18868..19227
                     /locus_tag="TV186_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532873.1"
                     /translation="MDYSPETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKARMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            19239..>19447
                     /locus_tag="TV186_001489"
     CDS             19239..>19447
                     /locus_tag="TV186_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1532874.1"
                     /translation="MANTKEGTTIEITTGKPIVGKKIFYFIQSVDAKKGSKALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKAT"
BASE COUNT         6579 a         3303 c         4403 g         5162 t
ORIGIN      
        1 attgaccgca aaatcaaagt tatgggcata attaatagcg aaacagaagc gtttaaactt
       61 gagctaaata aaaaacaagt cagcgagatg ttaggagttg atcctaaaac atttgacgta
      121 agatttaata gccttaaaga ttttccgcgc atcgaaactg gaggtcgaga aaaatatccg
      181 cgagatgtag ttattgagtg gtatcgcaaa aactgggaaa gaacggggat aaaagcatga
      241 ctaagttaga tttattttta ttaataacaa ctcttgtgct agcgattatt acgagtgcgc
      301 agtataagat catcaaaaat tataactcgg cggggaataa acgcaaaatt tttgaagagg
      361 tggccttaga aaacagtaag aaatggagcg cggaacgtta tgactaagca ggagttacaa
      421 aaacaactac tagatattat ggccgaattt gatagcgcag tcgaagctct gcttgattta
      481 aacgagtctg gagaaatctc ggaccaggag ctcttgttaa atttaaaagt tagatataag
      541 agctattcag gagaaaaaat ttgtattatc gacaaactta ttaagcttgg aggtgcagaa
      601 cgatgacaac ttttgaaaag gttattagta agcttaatcg aatcgaggga gaattagcta
      661 aacctgaatc tgaacgacga gataattcat atcacttgtc cgccctgttg ggttctatta
      721 aacaagattt aaaattgatg ctttggattg agctgccttc gttaaataat gtggagaaat
      781 acgaagctct ttatcaagga aatgatttta aattcagtga aactttctta gagcgtcaag
      841 cgacaagaaa agccttttgg agacgattag ctaaggaaac ttttaaagaa gaccaggata
      901 ggaggaactt tgttaagttg gctgagaaag aatttaaagg tgcaactttg tcatggcaag
      961 aatttttgtg gggtaaaaag aaatgaatat ttcaataaaa ctcataggtg aaaccctagc
     1021 tggtttaaat gatattttac gccagggggg gctctcttgc tcccaaaacc aagccttagc
     1081 agacgcagtt tttatattaa cagctttaaa acaagtaatt gaggagagaa aatgaactat
     1141 ttagaatatg cactagttta tcttgaacgt gagttagaaa ttattgataa cgaagttatc
     1201 gaagttgagt tgccgggcgg ggattgggag tttgtgccta atccctacta cgagaaaggt
     1261 ctacatgata gcccacacta tcgtagtcag gttgctaaag acattcttga tattaaagga
     1321 cttttgggga ggtgaggcta ttgattgcat caaaaaagac ggcttaggaa accgtcaaca
     1381 attatacaca cttaaattat aacacagaaa gagagaaaca caatgattga agtaactttt
     1441 aaagcagaga gcatggcagg tgttttcgat gctatgcgtg aagctctgga tatgccgaag
     1501 acagtaacca aggatgttgt tgaagaaaaa ccagctccta aaaagaaaga agagtctgta
     1561 actttgacat tagctgatat taagaaaatg gctaaagcca aggttgaaga agggaagtca
     1621 aaggacatca aggaagtctt gaaagagatg aacgtcgcaa aagttggtga acttgaagaa
     1681 taccagtttg cggagtttgt tgagaagttg gaggctctct aatgccagta gaaaatcacg
     1741 cactactgtc tgcttctagt gctcacagat ggctctattg ccctatgtta cctagactgg
     1801 aagcagacta tcctagccgc gacaccgtat acactcaaga gggcacaagc gcccacgagc
     1861 tttctgaaat caaactgatg tacaagtctg gtaaaatcac caagcgtaaa tttaacacgt
     1921 taaccaagac ttttaaggaa aactcagact tctacaacga agagatggaa gagatgacgg
     1981 agctttacac agatattgtt atggagcacc taaatgctta tgagaacgcc gaaattgaac
     2041 ttgaaaaacg ggttgatttt agcgactggg tgcctggcgg ttttgggact tcggatgtcg
     2101 tcattttggc ggatggagtc attgaaatta ttgatcttaa gtatggtaag ggcatgcctg
     2161 tgtctgctaa tcaaaacccg cagatgggac tgtacgctct aggagcttat gcttcctacg
     2221 atatggtcta tgactttgac cgtatcaaga tgactatcat tcagccgcgt ttagattcgg
     2281 ttagttctgt tgacatttat gtagaggagc ttctctattg ggcggataat attgtcttgc
     2341 ctatggccgc tcaagcagac gcaggtattg gcgactggaa cctaagtgaa aaagtattgc
     2401 agtggtctcc tgtcgcagct aaattggtgc caagagcgca agaaaactgg gaattaattg
     2461 ataaatatga ctatcaggag cctgtctatt tatctgatga agccgtcgca gagatccttg
     2521 acaaagcctc agctatcaag aagtgggttg agtcagttga agcctatgcc ttgaaagaag
     2581 cactctcagg aaaagaagtt ccaggctata agattgtcga aggtagaagt aatcgagtta
     2641 tcactgataa agacaaagca attgatattt tacaagataa cggctttgac gatgagattt
     2701 ttaaaccgaa agagctgtta gcaatgggag cccttgaaaa gttaataggt aaaaccactt
     2761 ttgctgattt attagcagaa gtaattgata aaccacaggg caaacctgta cttgtccctg
     2821 aaaaggataa gcgcccagca ataaacagtt tagaacaagc aattaaagat tttgaatagg
     2881 agaaaaataa ttatgacaac aacaccaaac acaactaaag tagtgaccgg aaaagtacgc
     2941 ctaagctatg tagctttact agagcctaaa gcctttgaag gccaagaggc taagtattca
     3001 acagttatct taattccaaa aacagacaaa gtcacaatca agaaaattaa agacgcgcag
     3061 aaagctgctt atgaggctgc caaggacaat aaactcaaag gggttaaatg ggagcgcgtt
     3121 aagacaacgc ttcgtgacgg tgacgaggaa atggataccg aagagcaccc agagtacgct
     3181 ggtcacatgt tcatgtcaat ctcaagcaaa actaaaccgc agatcattga caagtataaa
     3241 aactctgttg attccgcaga agaagtctac tctggcgtct atgctcgtgt atcacttaat
     3301 gcctatgctt acaacacggc gggaaataaa gggatctctt gcggattaaa caacgttcaa
     3361 attgttgcta aaggagacta ccttggcgga cgttcgtcag ctgatgcaga ttttgacgag
     3421 tggaacgaag aagaggacga agacgatatt ttatagtaga gagcctcttt agaggctcct
     3481 catttttaaa ggagaggtat gagacattta aatattgata ttgaaaccta tagttcgaat
     3541 gacatcaaaa atggggttta caagtacgct gacgctgaag attttgagat tttacttttc
     3601 gcttactcta tagatggcgg agaagtagag tgccttgatt tgacaaggca gtctctacct
     3661 gaagacatca aagatatgtt atttgatgat aaagtccgaa agcacgcctt taatgcccaa
     3721 ttcgaaagag tttgtctcag tcgttacctc ggcctacctt actatctaga tccttgccaa
     3781 tggcaatgca ccatggtgct ggcccaagag ttgggtctgc cttcaagctt ggaaaagtgt
     3841 gcgctgtatt taaaattagc acaggaaaaa gatacctcgg gtaaaaactt aatcagatac
     3901 ttttccctgc cttgcaaacc aagtaaaact aacggtggga gaactagaaa tttaccagaa
     3961 cacgcccccg aaaagtggca aatgtttatt gactactgta tccaagacgt tgttgttgag
     4021 atggcaatcg ccgaaaaact agaatcagtt cctgtgcacg accgcgaatg ggactactac
     4081 gcctgcgacc agagaatcaa cgacagaggc gtggcacttg ataaagagtt agttgcttcg
     4141 gctttgtatt gtaaagatgt taagatggaa agtttgtctg gtgagctaaa agccataaca
     4201 ggacttgcta acccaaacag tagagctcag ttgctaccgt ggctaaaaga acacggttat
     4261 tcggctaacg ggctgactaa agcagatgtt gaacaggaac ttaagacggc tgaaggagaa
     4321 cttaagagag tcttagaact taaactacaa accgctatgt caagtctaaa aaaatatgaa
     4381 gctatggaaa gagctatgtg ctcagacgga cgagttcatg ggctacttca gttttacggg
     4441 gctagccgga caggaagatg ggcgggcaga gttgtccaag tacagaattt agctaggaat
     4501 tatataaagg atctagatga tgccagggag tatgttaaaa agcgtgacat tgatgctgtg
     4561 gagattttat acgatagcct taatgacact ctaaagcagc tcgtgcgaac cgctctcgtg
     4621 gctaaagatg gctgtacctt ctatgtctct gacttctcag cgattgaggc tagggtgatt
     4681 gcatggtttg ctggagagca gtggaggctt gacgtgtttt cgacgcacgg gaaaatctac
     4741 gaggcgtctg ccagtcagat gttcggaatt ccaattgagg agattgacaa ggaactacgc
     4801 caaaagggca aaatttcaga gttagcactt ggctatcaag gaggtcctgg agcgcttaag
     4861 cagatggggg ctctaaatat gggagtcaag gaagaggagc ttcaagggtt agttgatgac
     4921 tggcgcaggg ccaataagaa aatcgtccaa ttttggaaag acgtacaaag agccgccatc
     4981 aaagccatca aatcgagagc accgataaaa cttggaaaac tacgatttag ataccggaaa
     5041 ggtttcctct ttataacatt gcctagcggt aggaacttag cttatgcaag agccaaggtt
     5101 gagccaggcg actatggaga caaaatcatc tatgagggcc aaggagataa ggcatacttc
     5161 acagcgcaag agacttatgg cggtaagctt gtcgaaaata tcgttcaggc gacggctagg
     5221 gatattctag ccgaagcgct tctgagaatt gaagctgcag gctatggtgt tgttttccac
     5281 gttcatgatg aggctattat cgaaggctca ggcctgacaa tcgaagaggt taatgatttg
     5341 atggctcagg ctcctgaatg ggcggagggt cttcctttaa atagcgaagg ctatgtaaca
     5401 aagtattata tgaaggatta gatagatgaa gcaagaaaaa ctaatagtaa agtcttctcc
     5461 cctgcaagag cttcatatcg caacaggtag ttcgcgaaca gctaagacat ggaaaaatat
     5521 cacgctaact tggcaggagc tggttgagag gttagagaaa cctacagtca cccaagagac
     5581 gtttgcggag taccagaaga tgtctcgagc agaaaaaggg caagcaaaag acgtaggggg
     5641 ctttgtcggt ggatggctaa agcaaggtaa gcggaaaaat gaaaacgttc aaagtaggtc
     5701 cttggttgcg cttgacgcag atagcccaag taaagatttc ttagataggc tagacctgct
     5761 tgcggattat gcctacgtac tctacagtac tcacagccac tcaaaaaaag ctgctaagta
     5821 ccgtcttatt atccctactg accgtttaat gatgcctgat gaatatgagc cagtcgctag
     5881 atatttggct aaccaactag gcatgtcaaa ctttgatgac acgacttatc aaagcgtgcg
     5941 cttgatgttc tggccgagtc actcaagaga tgcagacttt acgtttaaat ataacgacga
     6001 ggcttttctg agtgttgatg aggtgcttga tacatacccg gactggcatg actcaagctt
     6061 ctggccagaa agcccgacgc acgctgttaa aagacagcgt gaagctaaaa aacaaggtga
     6121 cccgcttagt aaaaaaggac ttattggagc cttttgtcgt aactatgaca ttagacaggc
     6181 cattgcaaca ttcttacctg aggtttatga agaaggaacg actcctgata ggtacaccta
     6241 cactgatggc tcaaccgcaa acggcttagt tatctatgat gatgtcttcg cttatagcca
     6301 tcacgggaca gatcccgtgg gggatacgct tgtaaatgca tacgaccttg ttcgtatcca
     6361 taaattcgga gagcaagata gcgaggctaa agataatact cctactaata agctaccatc
     6421 aagcaaagcg atgaatgctt ttgtctgtga cttacccgaa attaaagatt atctaatggc
     6481 ggaggcttta ggcgatttcg atgaagagtt accagtcgaa gatgacagaa gctggcttga
     6541 aattgatgag aggggcgaac cggaggtcaa tagttatttg ctagcaacgc agattattaa
     6601 ggaggttccg atttattggg atggcttaga atttttacgc tacgacgcta aaaaaggcat
     6661 ctggttgcca aacgctgagg aatatttgaa gagttatatc tcaactaaga aactcggtaa
     6721 aatcactaag attaggcaca ttagcgaaac cattgtagcg attaaagcac aggctttctc
     6781 aagcgaagtg tttaccgaga gtgatcttaa caagatagtg ctagtaaatg gagtctatga
     6841 cctgagggat aacagcttta agactaagtt tgatccagaa ttgcatgcca ggtcaagcca
     6901 tcccgttgcc tatgcccccg aggcggcctg tgaaaccttt gagggttttc ttagggagac
     6961 cgtcggagct gaaaatatag atttcatctt tgagtggttt ggctataact tttatcgtga
     7021 atacactatt caaaaaatgc tattcatcta tggcagcggc ggtacgggta aatcaacact
     7081 gattaatatt ttacgtgaaa tgataggtgc tgataattat tcagccgtga cactgcagta
     7141 cctgatgcaa gaacgctttg caaaaatcgg cttatatcgt aagacagcca acttcgatac
     7201 cgatgctaaa cctcaatact tagcagatgg cgcaacgctt aaaatgttga ctggggaaga
     7261 tacgatacac gcagaccgga aaaacaaaga gcctattaat ttttacaatt acgccaagct
     7321 gtcttttgcc atgaatgagc tcccacctat gcgagatttc agtggaggac ttaagcgccg
     7381 catgatgatc cttgagatgg ataaggtatt aacgcaggag gttaaggcaa aatacccact
     7441 agataagatt atgagtgagg tgcctggtat ctttaacaga gcgatggagg ggcttagaaa
     7501 tgccttaagt aagagagatt tcagtattag tgccagcatg aggtcaagtg tcgagaaatg
     7561 ggaaaaaggc aacgatgtcg tggccatgtt ccttgaagac gagtgtgaac ttggtgaaga
     7621 cttcaaagtt cctgttaggg acgtctaccc agcctataaa ttctattgtc aggattcagg
     7681 ctacaaacct ttagctagga attcgtttac gcaaaggatg aatgaactga attttgaaaa
     7741 taagaacgca aaaatggggg gcaagaccgt aagatgttgg ataggtttta ggataaaagg
     7801 agaattttaa agggttacgt ttttcaataa aaaaggtaaa caggagacat aaggttacgt
     7861 agttacgcag aattcagact gataaaaaat tttataagtt gaaaaaaaac gtaactacat
     7921 aactttcctg aaaaaacttt cctgtttaag tcgatttaca taactaacgc aacttttatg
     7981 caacctcaaa aaacctttca tagcaatagt ttagacccta aggttatgta gttatgtttt
     8041 ttcttctatt aacttaaata taaaaaataa atatatataa aataaggcat atataaaaca
     8101 cgtatataaa aaagaattaa taagttgaaa aaaaacgtaa ccctgacctt tattgaccaa
     8161 aggaggaaag atgaggactg aaaaagatat tgaaaattat ttgaaaaaga aaacaaaagg
     8221 gctgtgttta aaatttacca gtccagggac gataggagta cctgacagaa ttgttgtcat
     8281 gaatacggga accttttttg tagaggtcaa agcgccaggc aaaaaaccaa gacccagcca
     8341 agttgccatg cacaaaaaaa taaaagaggc tgggcagcac gtttgggttg ttgactccta
     8401 cgaatcagtg gacatggcct taaaagaaat ggagaactgg gtgtgagact gcacgagtac
     8461 caagaatacg ctaagacatg gatagtagag cacccttatt gcggcctttt acttgacatg
     8521 ggccttggta aaacgctgac aacactatcg gcgatagatg agattcaaaa tattttttcc
     8581 gaggatcata agattttaat cgtagcccct aaaaaagtgg cggaagaaac gtggcctacg
     8641 gagattgaga aatggcattt tgatttcacc tactctaaag ttttggggag cgagggaaaa
     8701 cgaattgagg cgttagaaac agaagctgat atctatttga ttaatcgtga gaatgttact
     8761 tggcttgttg aatactacaa gactaaatgg ccgtttacct ttgttgttat tgatgagctg
     8821 tcaagcttta agtctagtaa gtcaaaacgg tttagggctt tgcgaaaagt tagaccgaaa
     8881 gtccaacgcc ttgtaggact aacaggaacc ccagcgccta acagtttgat tgatttgtgg
     8941 ccgcagattt atctgatgga cagaggcgac aggcttgaga ctagccagac tcgatttaaa
     9001 gacaagtatt ttgttcctga taagcgtaat ggtccaatcg tgtatagctg gacacttagg
     9061 gatggtgcag aagcagaaat ctataacaag attgaggata tctgtgtcag catgaaagct
     9121 aaagactatc tcaagttacc gccgcgaacc aacaacgttg tatcagttaa gttatctaat
     9181 atgaaagctt acaaacagct tgaagctgat ttggtgttgg agtttaagga taaggaaata
     9241 tctgcggcta actctgcggt tttggtcaat aaattactcc aaatggccaa tggcgctatc
     9301 tatgatgctg ataaaacgac agttgctata cacgatgaca aacttgacgc gcttgaggac
     9361 atagtagaag aaagccaagg ccagccaatc ttagtttttt atcagtatca acatgatctt
     9421 gaaagactta agaaacgatt ccctcaggct gaagagttga cgtcagttga caagtggaat
     9481 tctggaagaa taccaattct tctgtgtcac cctcaatcag ctgggcatgg gcttaatcta
     9541 caaaaaggcg ggcatattat tgtttggttt gggctaacgt ggagtcttga atattatcag
     9601 caagctaatg ccagattaga tagacaaggg cagacagaac ccgttattgt gcaccacatt
     9661 gttgcagaaa atacagttga tgaaaaagta cttaggattt tacaaggcaa agaaaaaaat
     9721 cagaacgcct tacttgaagc agttaaggcg cagttagggg tctagatgaa aaaagaatat
     9781 gtcgttagaa tctacacggg tagagaaaag aattttgagg caaaacctca gtttgaagag
     9841 aaaaccttta cgcgaaaagc agacatgttg aggttttggg attcttgcga agcagcagtt
     9901 aaagaaaaat atactaggga gtggaaaaaa tgacaaaaca agaactaatt gaagaaatag
     9961 aagatgaaat caatgacata gatcttttga ttgacgatta ccaatacgaa attgacgaat
    10021 tagaacgaga tatagacgaa ttagatactc aaaaagatat tttgaagcgt aaattagata
    10081 acctgttaga aagcgtggaa tgatgactga acaacagatg attgattgcc tgctttatga
    10141 gttagcaaaa aaagacaaag caatcaaaaa taaaagcatc attatcgctg tactaacagc
    10201 tgtgctgtgt ctcgtgtctg ttttaagcat cgcactgcaa aaccactacg aaccacaaat
    10261 tacaggttta cagtcacaat tacgcaggac gcagtatcag cttaagcgag ctagcgagga
    10321 tagagctaga cagacaaaac ggattgcaga attgactgga aatgggggat gattatgttg
    10381 ctaattgacg aagtaaaaaa atgtgaatca tcttatgaga tatttagtaa accagttgta
    10441 ctaagtagag atttatatat tttttggagg ataggagatg aggatggaca ataacacagc
    10501 agctgttttg acactgctaa tactattttt accttttatt attggaagtt ttagagatta
    10561 agcgaggtaa cgagatgagt agattatcta atgcacagct aaaggctttt gatgaatggc
    10621 tgtttgatta tcgctttatt gataacaaga ttgcacttcg aaaacttgag ctacaaactg
    10681 atatgaatac cgaagtagat aaaaatatcg gtggaggaag agcaaatttt gtttcaaaag
    10741 ttactgagga tgtggttgca aggtgggatt cagataggga actaaagggt ctatccaatt
    10801 tcaaagaagc agttattgca acgctaaatc ttttggatga agaactaact gatattttta
    10861 atcttaggtg gggcgttggt tcaagtaaca cttgggaaga aattgcctat acaagacatc
    10921 tgtcgcgtaa gtctatttac cgcaaaaggg agcggattct agaaatattt tccaaaaaaa
    10981 taggaatgtg acacaaaaat gtatggaatt gtcatctttt tgatgataaa ttggtagtat
    11041 gagtttaaag gtaaggcaaa tagtgtcttg cctttttgtt atgcttggag gtgatggaaa
    11101 attgagtaaa ttaaccctaa aacagaagcg ttttgcagat gagtacatca tctcagctaa
    11161 cgcgacagca gctgctatta aagcagggta tagtaaaaag acagcaaggt caataggtca
    11221 agaaaacttg accaaacctg acattaaagc ttatatagac gagcggcttg aaaaacttga
    11281 atctgaaaag attgctacgc aagaagaagt cctacaatat ctcacttcaa ttatgcgagg
    11341 agaccaacaa gaaaagacgc tcattagcgt tggagagttt ggccagaaga tagttgacat
    11401 cgatgttggt gccaaggata gaatcaaggc agctgagcta ctaggcaaac ggtacaggtt
    11461 atttactgac aaggttgaaa tggatgtcag ctcagatgta accattaacg taggtgagtg
    11521 ggatgacgac taaacagcgc cctaaaatta atatcgtaat caagcatcct agcaaagttt
    11581 ttaacaaaca tatctacgac aaactttaca actatagcaa cttcacggaa gttcattatg
    11641 gtggggcgtc tagcggaaag tctcacggtg tttttcaaaa gataatttta aaagcactta
    11701 accccaaatt caaacatccc agaaagatat tagttctcag aaaagtcggt gcaaccgtta
    11761 gagactctgt atttgctgat atcatgtcta atttgtcgta tttcggcatc ttggataaat
    11821 gtaagataaa tatgtcggct tttagaataa cgctcccgaa tggctcggaa ttcattttta
    11881 agggtatgga taaccctgag aagattaagt caattaaggg gatatctgat gtcgtcatgg
    11941 aagaagctag tgaatttacg cttgatgatt atacgcagtt gactttgcgt ttaagagata
    12001 agaaacatct agagaagcaa atatacttga tgtttaaccc tgtgtcaaaa gtaaactggg
    12061 tttataaagc cttcttcgtt aagacaccta agaatacagt tgtctatcaa acaacttata
    12121 aagacaaccg cttcttagat gatgtcacga gagaaaatat tgaggaacta gccgatagga
    12181 atgaagctta ctacaaaata tatgctcttg gccagtttgc tacacttgat aaactaattt
    12241 ttcccaaata tgacaagcaa atattaaaca aagacaagtt atcacacttg tcttcttttt
    12301 ttggtttgga ctatgggttt atcaatgacc cttcggcatt tttgcatgtt aaaatcgatg
    12361 acgcaaacaa gaagttatac gtcatagagg aatatgtcag aaagaatttg accaatgaca
    12421 aaatagcaaa tgctataaag gacctcggct atgccaaaga agaaatcaga ggagattcgg
    12481 ctgaaaagaa atctaaccaa gagctgagga atttaggtat tcctagaatg attgatgtta
    12541 ccaaagggcc tggaaccgtt atgcaaggaa ttcagtacct gcttcagtat gattgggttg
    12601 ttgatgaaag gtgtgtcaag actattgaag aactcgaaaa ttacacttgg aagaaagaca
    12661 agaaaactaa tgagtatatc aacgaaccag ttgacagtta taaccactgc attgacgcca
    12721 taagatatgc cgtacaagac agaatatacc agtcggcgga tagaagtaag cgcatgaaaa
    12781 atgctaaata ttatttttag gaatgaggtg agactttgga agaaaaacaa tttttagcag
    12841 gaactcgttt taatgagaat gctaataagc aatttattat gctgcaagaa gactttgaag
    12901 caattgacta tgaatcaaaa ctttggatag atcaacttaa gaattacatt tcaaggttta
    12961 aagcagaaca attagagcgt ttgaaagagt taaagcgata ctatcttggg gataataaca
    13021 tcaagtatag acctgctaaa acagataaat acgcagcgga taatcgtatt gcaagtgatt
    13081 ttgctaaata tattacggta tttgagcaag gttatatgct tggtgttccc gttgagtaca
    13141 aaaatgaaaa taaagacctc caggcggcta ttgaccttat gtcggtcaga aacaatgagg
    13201 actaccacaa cgtcaaaata aaaacagatt tatcaattta tggaagagcc tacgagctgt
    13261 taactgttga ggaaatagat gacaaaaaaa ccgaagtaaa actctaccag ctcccagccg
    13321 agcaaacttt tgttatctat gatgatacat accagcgaaa ttcgttgatg gccgttcatt
    13381 tttacgacat agattatggc tcaggtaaac gcaaacagat tatcaaagta tatacttccg
    13441 acacaattta cacctacgaa gactataatc tcgaaacaaa aggtacgtgc ttaaaagagc
    13501 atgaagaaca tttttttaaa ggtgtaccag tcaatgaata tgctaataat gaggagcgta
    13561 caggggctta tgagtctgta cttgataata ttgatgccta tgatttatct cagtccgagc
    13621 ttgctaattt tcaacaagat tcagtcaatg cgttgcttgt aatagctggt aatgcttaca
    13681 caggggctga tgagaatgac tacttagatg acggacgatt aaatcctaat ggtcgcttag
    13741 cgatctcaat tgggtttaaa aaagcccaag tgttaatttt agacgataat cctaatccaa
    13801 atggcgttaa accacaagcg tactttctca aaaaagagta tgataccgcc ggtagcgaag
    13861 cctacaaaaa tagactagtt gcagacattt tgaggtttac ttttacgcca gatacacaag
    13921 atatgaaatt ttcaggagtt caatctggtg aatcaatgaa gtataagctt atggcttctg
    13981 acaactatcg cgagaagcaa gagaggttgt tcaaaaaagg cttaatgcgg cgcttacgct
    14041 tagcagctaa tatctgggcc atcaaaggga atgaagcaac tacatatagc cttgtaaatg
    14101 atacgagtat agttttcaca cctaatcttc ctcaaaacga taatgaaatt gttacagctg
    14161 cacaaaatct ttatggcatt gttagcgatc agactatctt tgaaatctta aacactgtca
    14221 caggagtaga cgctgaagca gagcttgaac gtttgaaaga agaagctgat aaaaagcaat
    14281 ctttaccgga gcctagattg gtaggtgatg ctagtggtca agaagaacca acagcagaaa
    14341 agccttaatt actggcaaaa gcgtcaagaa gatattctaa gttatttaga cagagctgat
    14401 ttagatgtct tttcagaact gcagaagtta tataatgaac aggcttttga gttacaaaag
    14461 gaattgtttg atttttatac taagtattct gaagagaaca aaatgactta tcaggatgtc
    14521 gttaaaaagc tacgtcatga agatttatca gattacgtag ctaatgctaa caagtatcgc
    14581 aaacaagctg agaaagaccc tgagctgcta aaacgactta atgagcagta tgtatcagca
    14641 agagctacaa ggatggatgc attaaatctt gaacttgttt attgcgcagg gatactaaaa
    14701 ggtgtacttg attcagcatt tgaaaatcat ttaaaaaaag ctgcctcata tgcttataaa
    14761 aaagcaatgg gtggacggtc agggacaatc aatggtccag ttttagaaga actggttaga
    14821 accccgtttg atggttataa ctactcagaa cagttgtggg gcaatactga caatcttgtc
    14881 aagaatctcc aaaagaaatt aaaacaaggt tttgttcgtg gcgagcatcc tagagcgata
    14941 gccagagatt tagctaagca atttaatgtt gctaatcaca gggctgaaac actaatcaga
    15001 actgatggaa ctatggtgat taataatgct accgctaggc gctacttgga tgcaggactt
    15061 aagtattatc gtgatttagt taggcttgat gacaggacaa ctgagatatg tcgtaaaatc
    15121 gctaaagaaa acaaaagaaa gctattatct gagctaaagc ctggaattaa tgcagcacct
    15181 tatcatttca gctgcagaac aacccttatt cctgatgaag atgagctaag cattgaagta
    15241 gaaccaattg atgataaaag cactaagtat tttaaggatg tcacctcaga ttggatagat
    15301 ggaaatgggc ataaaccaca actgtcacta ctaaatgagt atgtaaaaaa tggcactcct
    15361 tacaaagtag atggccataa tgttgttctt gatcactcga attatgaata tagagttgct
    15421 aattggttat ctaaaaagac aggattgcaa gttgacatgg tgccaagagt taattcccct
    15481 gaacatatca atactcctga ttatttagtt gatggagttc cttttgatct aaaagaaatc
    15541 acaggttcgg gtaaaaacgt cattgatggc aatctacgaa aagcaaaaaa gcaggcaact
    15601 aatatcattt ttgatataac aaaaacccct ttatcatttg aagagataat ggggcagtta
    15661 gaacaaattt atatgataga tcgtaggggt cttgatatat caattatcaa aaataaagat
    15721 gaggtattag ctgtattaga aaaagaagga tgatgaccca ccgcctccac agtaaactgc
    15781 ttcgtgggcg ttagaccatc atccttcttt atctcaatta tacatcaccc tattaaaact
    15841 atcaaggagg aaaatatgtt tatttggcaa atggtattag tggcactagg tgtattggtg
    15901 ctcatattga ttgttggcat tgcagcaata gcggttaagt caattattgc agaattgaaa
    15961 aaggtaggat aaacatgaat aagcgcatta agaaaaaacg taagttggaa acagcggttg
    16021 tgatgcttgt tgcagagaat gccatgcaag cagaagcaat taaaaatcaa aacaaagaaa
    16081 tcatggagtt gaaatcaatt gttcagcgga acgctctggc aacaaacgaa gagtttgcgt
    16141 ctgttaaagc tgctacttta gataatcaag cagctattac aaacattgca attgatgtta
    16201 actacattaa gaaaaattat aagcgtaagt ggggaaaata aattttaaac gaattcgacc
    16261 cctttagaaa tcaaagtcgt agcaatacgg cttttattgt gtccaaactt tgttgatgac
    16321 actaaaagct acactgtttc gtcgcaggac gtaaagctag actatcggtt ggtggcgtaa
    16381 ccactaggag aaagttatgg cagaagagaa tgtaacaaca gaaacaactg agcaagtcga
    16441 cactcaaaaa gaagctgttg aacatcctaa gcaggaacat gagcgaactt ttactcgcgc
    16501 agacatctca aaaatgatgg ctgccgaacg cactaaatgg gaatctgaac aatcagaagc
    16561 tattgaaaaa gctcgtacag agggtgaacg tttggccaag ttgtcaaaag atgagcgcgc
    16621 taaagaggag gaacaaaaac gtctagatgc tatcgcagag cgtgaaaaag cagtagcaga
    16681 gcgcgagatg cgcattgaga cgcattccct gcttgtggag aaaggattgc cattggattt
    16741 tattgatatt gttttagcca ctactgcaga agaggttaag accaatattg ataatttaca
    16801 aactattttt gataaagctg ttgaaaaacg tgttaacgat cgtttaaccc agaagccacc
    16861 acgaactgga aatggctcgg tcggcatgac caaggctgac atcatggcaa tagaggatga
    16921 tgacgaacgt atgcgtttaa ttgctgagaa tcgtaactta ttttaagaga ggaatattat
    16981 ggctgaaaaa aatttaaaca ctatggcgga cttaggagat attaaatcaa ttgattttgt
    17041 taacaagttt tccaaaaata ttaatgattt actaaaattg ctaggggtca ctcgtcgtga
    17101 aacattaact aacgatctaa aaattcagac ctataagtgg gaagtgactt tagatcaaac
    17161 tgatcctgga gaaggggaaa ccatccctct gtctaaggtt actcgaacta aagataaaga
    17221 ctatacagtg aagtggttca agaaacgtcg tgcaactaca gctgaggcaa ttgctcgcca
    17281 tggcgcagct cgtgctatta ctgaagcaga taagcgcatt atgcgtgagc ttcagaatgg
    17341 aattaaggat gcattcttta cattcctcaa aacaaaacca acaaaagtta aaggcgttgg
    17401 ccttcaaaaa gcgctgtctg catcatgggc taagctagct acttttaatg agtttgaggg
    17461 ttccccgctt gtttcttttg tctctccttt agacgtagcc aactatcttg gagatactaa
    17521 agtaggtgcg gatgcctcta atgtttttgg aatgacattg cttaagaact ttttgggtat
    17581 gcaaaatgtg attgttatgc catctgtgcc agagggtaaa atctactcaa cggctgtaga
    17641 gaatctagtt tttgcgtctt taaatgttaa aggcggagac ttgggcggct tgtttgctga
    17701 ttttactgat gagacaggtt taattgctgc agctcgtaat cgtcagcttt ctaatcttac
    17761 ctatgaatct gttttctttg gggcgaatgt gctgtttgct gaaattcctg aaggggttgt
    17821 agaggcaaca atcgaagctg ctgctgtacc cggcattggt ggttaaaggc tatttatatg
    17881 ggcgataaac aacttattga cgatatcaaa ctctttatag gtatttccaa gggggatggt
    17941 gcgcaagatg agctcatcac ccttgctata tctgaaagta aagagcgtgt gctagctaaa
    18001 cttaatgaat actcagagac tgaaattacc aaaattcctg atagattgag gtttattgtc
    18061 cgtgatgttg ccattaaacg gtttaatagg attaattcag aaggaaccgt tgaggatagc
    18121 gaagaaggaa agacttttaa gtgggacagt taccttaaag agtatgaatc aacactcaga
    18181 agcgctgcta ttgggaaggt atattcaggc aaaggggtag caagatttat ttaggagata
    18241 cacaatgatc tataaagata gagtaatctt agtgtatgtc gatgagcagg acgattttct
    18301 agataaaaga actgttgaaa aacctagcgg gaaaatcccc tgcatggaaa atactttcac
    18361 aaaatctgaa cagatggggc tatttggtaa atatgatttg aatgctttta agttgcactt
    18421 gcaaggccat tacgacggct ttagcaagat tatctacaag ggaaaaccga ggttgataaa
    18481 gggactagca caccataaaa atagcacggt tatttatgta tgagtcttat ttatcggatg
    18541 agaggcttag ataggttttt acgcagcgtt gagcgcaagc agaagtcagt acgaatcgct
    18601 gtagataaag agcttagcaa atcagctgct agaattgaga gacaggctaa aatactagcc
    18661 ccggttgata ctggatggct gagagctcaa atctacaacg agcaacaaca actcttacac
    18721 tatagagtgg tttctcctgc tttatattct gtttatattg aattaggtac tcgtaaaatg
    18781 gaagctcaac cgtttttaga ccctgctctg agaaaagaat ggcctgtgct aatggctaat
    18841 ctcaaaaaaa tgtttaagag gtgatgcatg gattactcac cagaaacact atatttaaaa
    18901 aaggtaaaaa atagattggg agttttggac ataccaatct attttaaatt gcctaaatca
    18961 gacgttttag agccttttat tgttgtgggt acaaatatat cagacttgtc aaaaacagct
    19021 caaactggag cagttattga cgattttagc ctgaatatcg atgctttctt acctggcgat
    19081 agtcgtttgg atgcagaaga gataaaagct cgcatgctta gactgcttgg gcggaataac
    19141 caaataaagg ctcagatttt ggtagataat tcaataggac gagaagtcta tagagttgct
    19201 atcaacatta cagaaacact attttaaagg agacctaaat ggcaaacact aaagaaggaa
    19261 caactattga aattacaaca ggtaaaccga ttgtagggaa aaagattttt tatttcatcc
    19321 aatcagttga cgctaaaaaa gggagtaagg ctttgctgcc agcctatcgt accgatggta
    19381 ctacaaccat gggcggtgaa tacattgatg agcaaaccca acaaggccgc gttattgaga
    19441 aggctac
//
LOCUS       DARYXZ010000043        18659 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYXZ010000043 DARYXZ010000000
VERSION     DARYXZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18659
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(152..742)
                     /locus_tag="TV186_001490"
     CDS             complement(152..742)
                     /locus_tag="TV186_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532875.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
     gene            1265..3307
                     /locus_tag="TV186_001491"
     CDS             1265..3307
                     /locus_tag="TV186_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1532876.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            3309..3596
                     /locus_tag="TV186_001492"
     CDS             3309..3596
                     /locus_tag="TV186_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1532877.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            3609..4952
                     /locus_tag="TV186_001493"
     CDS             3609..4952
                     /locus_tag="TV186_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL1532878.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            4955..5812
                     /locus_tag="TV186_001494"
     CDS             4955..5812
                     /locus_tag="TV186_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1532879.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            5809..6741
                     /locus_tag="TV186_001495"
     CDS             5809..6741
                     /locus_tag="TV186_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL1532880.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            7293..9188
                     /locus_tag="TV186_001496"
     CDS             7293..9188
                     /locus_tag="TV186_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL1532881.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(9388..10428)
                     /locus_tag="TV186_001497"
     CDS             complement(9388..10428)
                     /locus_tag="TV186_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL1532882.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(10596..11366)
                     /gene="rpsB"
                     /locus_tag="TV186_001498"
     CDS             complement(10596..11366)
                     /gene="rpsB"
                     /locus_tag="TV186_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL1532883.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            complement(11827..13359)
                     /gene="ahpF"
                     /locus_tag="TV186_001499"
     CDS             complement(11827..13359)
                     /gene="ahpF"
                     /locus_tag="TV186_001499"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL1532884.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(13380..13940)
                     /gene="ahpC"
                     /locus_tag="TV186_001500"
     CDS             complement(13380..13940)
                     /gene="ahpC"
                     /locus_tag="TV186_001500"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL1532885.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            14288..14358
                     /locus_tag="TV186_001501"
     tRNA            14288..14358
                     /locus_tag="TV186_001501"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14320..14322,aa:Cys,seq:gca)
     gene            complement(14465..15532)
                     /locus_tag="TV186_001502"
     CDS             complement(14465..15532)
                     /locus_tag="TV186_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1532886.1"
                     /translation="MAKFRKRGDKWSYRIYYTDSQGNKREKSKGGFKTKALASAAAIK
                     VEAELNKDIDDISLYDFCKEWAKIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNNVT
                     HTFYQKTINEFAKKYAQETLEKLHYQIKGAVNVAVRDGLIKTNFAEGAIVKSQKEARA
                     KEFDFLEEDEYLNLIKVTSEKYQYVSYFTLYIIAVTGLRFAEATGITWSDIDFEKGFI
                     DINKSFDYSKTQEFKETKNEQSKRQIPIDQQTIKLLRAFKENYYNENKLNRVLYGASN
                     SLCNRLVKKIVGRPVRNHSLRHTYASFLILKGVDLISISQLLGHENLNITLKVYAHQL
                     DKLKEKNNQAIKDIFGNLTDF"
     gene            complement(15659..15934)
                     /locus_tag="TV186_001503"
     CDS             complement(15659..15934)
                     /locus_tag="TV186_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1532887.1"
                     /translation="MRYKVLFTKKAKKQLKKLDRSTAKQLYQWIMTNLDGTDNPRRYG
                     KALQANRTGEWRYRLGNYRILAEIIDDEVVIEVFKIEHRSSVYKIKR"
     gene            complement(15924..16142)
                     /locus_tag="TV186_001504"
     CDS             complement(15924..16142)
                     /locus_tag="TV186_001504"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEL1532888.1"
                     /translation="MIAMTLNLEKDDAYIADYIKENNIDTSNLTVDQFLEIIEDAKDL
                     YELRKAKAEDDGTRFSMEDVAKELGFAL"
     gene            complement(16158..16679)
                     /locus_tag="TV186_001505"
                     /pseudo
     CDS             complement(16158..16679)
                     /locus_tag="TV186_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059208.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            17068..17274
                     /locus_tag="TV186_001506"
     CDS             17068..17274
                     /locus_tag="TV186_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1532889.1"
                     /translation="MLNIDKVRKEKGVAIVDMADFLGVRAQTVSDKLRGTYDFKFTEA
                     LALQQKFFPEYDLEYLFNKAVDTA"
     gene            17324..17479
                     /locus_tag="TV186_001507"
     CDS             17324..17479
                     /locus_tag="TV186_001507"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532890.1"
                     /translation="MVTKFSEEIKIVRTKSSVYVNSVLDVADKKDPASVVAVAELLKA
                     YKSLTEL"
     gene            complement(17480..17683)
                     /locus_tag="TV186_001508"
     CDS             complement(17480..17683)
                     /locus_tag="TV186_001508"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532891.1"
                     /translation="MKRYIIEQLANETDTITIMFTNGKQHTFCQVANECPDNPNIIEL
                     KLSDAQYIVLVNLDQVTYISHHS"
     gene            17743..18204
                     /locus_tag="TV186_001509"
     CDS             17743..18204
                     /locus_tag="TV186_001509"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532892.1"
                     /translation="MQANRIFYGKEKPTNAVAGDCWFRDNELMILKDNWEASVNNLKS
                     PKVIGEIEIDLEQHDVLLTARGNRPPLLMIDGIMLGGVSKVIIINELSESCAIVSLNE
                     YIKENLFPFDDFESLQRLFQKGHQKLSVRELCLEKRLGEHSYQDHRKSCDE"
     gene            18346..>18659
                     /locus_tag="TV186_001510"
     CDS             18346..>18659
                     /locus_tag="TV186_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HEL1532893.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKEVRKYFIQVEKDFNSP
                     EK"
BASE COUNT         5198 a         3588 c         4010 g         5863 t
ORIGIN      
        1 tcagtcttta ttttttgtta tgtaaaaagt ataggtggtt atggccgaat agaaaactag
       61 ttttggagta aatgataagg ataagcgatt gaaacaatat gctattgctg tataaactga
      121 cattacaata ataaaataac aaatatagtt cttaagccca cgcatttata cgaccgttat
      181 ttgggtgata atctcgagca tcgacatatt gtgctagggc atatccgaca ttatagtaaa
      241 tgtttattac tgagaatgca gctctaagta aaccggaaat aaatccggtt agtacaccaa
      301 gtcgttgagc tgcagctttt gcagctcggc taagtacagc tcgagcggca gctactccat
      361 gtttggcaac gtactttccg atggttgcat atccactaat taacccgcct acaataacat
      421 caaaagccca agcgaattca tctaaggtta ctccttgccc gtcccataca ctagctctaa
      481 aagtgtatgg actcatggct ttatacgcaa tttcacgcat ttcttgttct gttaaatttg
      541 gataaagagc ttttttctct tggattaatg tatctaactc actttttgaa atttctagag
      601 gttgtgataa tttttcttca attacttttt cttcctgttg aattttagtc acttcactag
      661 catatacaat ggaaggtaca gtgttagcaa tgagtaataa ggacgctatc attgcgatga
      721 tcaattgttt tacttttttc attttgaatt tcctttctga aaacgatggt gatctactaa
      781 gggttaatta gctttactcc tttctaacca agatggtagt tatttgtcat ttaataagat
      841 atcttatagt ttcattatat tattaaaata ataaaacaca agtctttttt ggtaaccgtt
      901 ttcgtggtat aataaaagat taccagttaa ctattaagtc tgtaatcttg ttttaggctt
      961 atatctagag ttatcacatg ctgatgaggt caatcagttt ttttgattat ttggaacatt
     1021 tttgacggtt attactccaa agagctttag ctttggcttg gacttaggaa atcatgggga
     1081 caattgctta gcggcagaga tgggcttgtt tgctctttat tgatagttag gaggagctgg
     1141 tagcctgttt agattggcat cttgagccca agggctgttg atgatgttgg ataagaaatt
     1201 gtgcccaatg gggactagtt tattgtaacc gttttcgata gaatgaattt agaaaggaaa
     1261 tcaaatggtt gatagcaaag cagttgtcat tttgatgacg ttgatgactt atcaagactt
     1321 atcactttac gagctgagtg ttaagacaaa attcaccatt agagagatta aggaccgtat
     1381 tgatgagctg aatgagtttt tggctcagca tgagctctca gagctagatg caacaaggtc
     1441 tggctatcgg atcagtcagc agcttaaggc tgagtcagat catttgttta cgttgattaa
     1501 tgctgagcag gtttatcttt ctcaggcaga gcggatcaat cttatctatc tgtatacctt
     1561 ttgccgcagg gattttgttt caaatagtca ttatcaggac tttttaaagg tcagcaagaa
     1621 cacagccttg acagatatta aggccttgcg gcagaagctg gcagatgttg acttggaatt
     1681 aaagtatacc agagcaagcg gctatatctt agttggtgat gagattaata agcaccggtt
     1741 ggctttagta atgattgcta ctttgcttaa atctcctatt ggcttgtggg ccttggacta
     1801 tattttggct tcttggcact atcaggtgtc gtttgaagcg cttgaaaaac gtgtgagcca
     1861 tttttatcag acctttcaga tgtctccgat ccttgatcgt ctgcaggtct gtttgtacgc
     1921 tgtcatcttt attttatgtc gttaccaaag acgggttgat agggtcaagc aaagacaggt
     1981 agtggtttct gagcagctgg atcagctaac ggcccttttg gtggcagaaa taatgcagca
     2041 attgtctctt aagtatcagc tatttgaagc tgatgaggcc tattttcaat tgctgttagc
     2101 gggctgcttt gagggtgagg gtactgttgg tgatgatttc tttgaatcac taaccgttgc
     2161 gattgttgat caaatgcagg gggttgcttt actaagcttt agtcaggcag atcagctcaa
     2221 ggagaatttg aaaaggcatt tgattccagc ctattaccgt ttgcgctatg gtttgccaag
     2281 tgataatgat tataccttgc ggattaagga tagttattct gagctttttg acttggtaaa
     2341 gcagtctctg gagcctttag ccaaggagct gggtagtcct ataccagata gtgaaattgc
     2401 ttattttgtt cttcattttg gaggctattt aaagcagcag ggaagagatt ttcatcgtca
     2461 agcctatcag gctgtgattg tctgtcctaa tggtgttagt tcttctttaa tgatcaagga
     2521 gcatttaaag cttttatttc ctgatattgc ttttcggggg ctttcaaggc ttgatcagct
     2581 tgggcaatta gataagagcg gctatgattt ggttttttca acgatacgat tagagactga
     2641 taagcccttt tatttagtcc ctatgataat gactgatgag caggcttttc agctggtcag
     2701 cttggttaat cgtgattttc cagatattgg ctatcggcta gaggttgaag agctgctcca
     2761 tcttatcagc tcatatgcgg tcattcatca aaaagaaaag ctgcgctttg ctttgcagca
     2821 atatttaaga caaggtgtga aaagaaagga tattcgacca gtgttacaag acttaattac
     2881 caagaaaacc tatcaatcaa cctcagagca attggggtgg agagaggcta tttatttggc
     2941 ggctcagccc ttgttagaga gtgggcagat tcaagcgagc tacccggagg ctatgattgc
     3001 taaggttgag gagtttggta cttttattaa tctaggtaag gggattgcta tcccacatgc
     3061 gaggccagag gatggtgtga atcaggtagg tatgtcgatg cttgttttag agcacccgat
     3121 ttatttgtta gatgatccta agcaggagat tcgtttgtta atttgtattg ctgctattga
     3181 taatgaaaca catctaaagg ccctgtctcg gctgacgacc attttaagag acaatgagca
     3241 ggtcaaggct ttacttgcgt ctaaatcatt tgaggatatt aaaactatta ttgcagagga
     3301 ggcataaaat ggcattaaga attggtacag cctgtggttc aggcttaggg tctagcttta
     3361 tggttcagat gaatatcgaa tccgtattaa aggacttggg agtaaccggt gttgaggtgg
     3421 agcattatga tcttggtggc gcggatccca cagcggcaga tgtgtggatt gttgggcgtg
     3481 atttggcaga ctcggcagag catctgggag atgtgaggat tttaaatagt atcattgata
     3541 tggacgaatt gactagtctg gtaaaggcta tttgccagga aaaggggctt gtttagaagg
     3601 aggataagat gacattttta cttgatattg ttagcacacc agctattttg gttgccttga
     3661 ttgctattgt tggtctctta cttcaaaaaa agcctgctcc tgacattgtt aagggaggca
     3721 ttaagacctt tgttgggttt ttagtggttt caggtggtgc aggtatcgtg caaggctcac
     3781 tcaacccttt tggaacgatg tttgagcatg cctttcatct gtctggtgtt gtgccaaata
     3841 atgaggctat tgttgcagtt gctttgacga cctatgggtc agcgacagct ctgattatgt
     3901 ttacaggaat gatctttaat attttgattg ctcgctttac ccgatttaag tatatcttct
     3961 tgacagggca tcacacactt tacatggcct gtatgattgc tgtgattatg tctgttgcag
     4021 gcttgacgtc agtgtccttg attgtgtttg gtgggctggc cttagggatt atcatgagtg
     4081 tttcaccggc tcttgtgcaa cggtatatga tccagctgac tggtaacgat aaggtcgctt
     4141 tggggcattt tagctctctt ggttattggt taagcggttt tgtaggaggt cttgttggag
     4201 acaaaaccaa gtcaacagag gacattgatt ttccaaagag ccttgctttt ttgcgtgata
     4261 gtacagtaag cattacctta tcaatggcaa tcatttattt gattgtagct atttttgctg
     4321 gtcctacttg gattagtaag gaattatcct ctggcacaca tggcttggtc tttgccttgc
     4381 agttggcagg acagtttgct gcaggcgtct ttgtgatttt agctggtgtt cgtttgattc
     4441 tgggtgaaat tgttccagcc ttcaagggca tttctgaaaa attagtgcca cattctaagc
     4501 cggccttgga ttgcccgatt gcctatcctt atgcccccaa tgcagtgctg attggctttg
     4561 tttctagctt tgttggtggc cttgtgagca tggctgtgat gatcgtaagt ggaacgacag
     4621 tgattttacc tggcgttgtg cctcatttct tctgtggtgc cacagctggt gttattggga
     4681 atgcttctgg aggtgtgcgc ggtgcaactg tgggagcctt tttacagggt gttcttatta
     4741 gctatcttcc gattttcttg atgcctgttt taggcggctt gggctttgag ggctcaacct
     4801 tctcagatgc cgattttggc ttatcaggta ttttactagg aacacttaac agcataggtg
     4861 gtgtgacagc tattgtgatt ggtatttttg tgatattagc tggacttgtt gggctttctg
     4921 ttgttggaaa atcagtagct aaggaggaat aagcatggtt ttgagtgatg agcctctaac
     4981 agatgtgaag cgattcgcag cagagattcg tctaaatacc ttggagactc ttaatcatct
     5041 tggctttggt cattatggcg gtagcttgtc tattgtagaa ttgctggctg tgctttatgg
     5101 agaaatcatg cccatgacac cagagctctt tgtccagtca gatagagatt atctggtgtt
     5161 atcaaaggga catgcgggtc ctgccctcta tagcactctc tacttaaagg ggttttttga
     5221 taaggccttt ttacagtctc ttaataccaa tggaacaagt ctgccctcgc acccagatcg
     5281 tctgttaacg cctggtattg acatgacgac aggctctctt ggtcagggaa ttagcgtagc
     5341 aacgggcatt gcctatgctc aagcgcttga gcagtcacca cattatacct atgcaatcgt
     5401 tggtgatggg gaattaaacg agggccaatg ctgggaggct atccagcttg cggcacacca
     5461 gcagctaagt catttcattg tctttgttga tgacaataag aagcaattag atggaacaac
     5521 cgaggcaatc tgtcgtccag gtgattttgt tgaaaagttt acggcatttg gctttgaaag
     5581 cttacgtgta gatggtaggg atgttcaggc tatttttgaa gccatcaggg ctttgcaggc
     5641 gtcatcaagt cataagccca agtgtatcgt cttagatacc gtcaagggtc agggtgttag
     5701 ccagctagag tcaatggcag ctaaccacca tctaagacca acagcagccg aaaaggagat
     5761 gcttgctgcc gctgtcagaa agctacgagc tagtttggag gtgacaagat gactcgagca
     5821 agtcaagaaa tgcgtcatgt ttaccgagat ttcctcattg cagccaacca agagcaccct
     5881 gaggtagtcg tcttagaggc agatttatca agctcaatgg ccaccaacca tttggatcag
     5941 gtgtttggca agcgctatat taatgtaggc attatggaag cagaaatggt cggtctggca
     6001 gcaggcctgg cgattaaagg ctataagcct tacctacaca cctttggtcc ctttgcctca
     6061 cgtcgtgtgt ttgatcagct gtttctttca ttagcctatg cccagctagg cgcaacggtt
     6121 attggctctg atgccggagt tagtgcggaa atgaatggcg gcacccatat gccctttgag
     6181 gatctgggac tgctgcgcct gattccaagg gctattgttt atgaggtcag tgatgacgtt
     6241 caatttaaag ctgttttaaa ggaaacccta tcactcgatg gcctaaaata cattcgaacc
     6301 attcgtaaaa agccagaggc tatttatcaa gggcatgagg acttttctaa tggctattgc
     6361 ctattgcgtc aaggaaaaga ccttgtgctg gcttgctcag ggatcatggt caaaaggtgc
     6421 ttagaggtag ccgataaaat ggcagagcag ggctactcta tcggtgtgat tgatgttttc
     6481 agggtaaagc cactggccga tgagctaaag ggtctactta caggcagtcc tgttctaacc
     6541 gttgaaaatc ataatcgtat cggtgggctt gggagtgcta tctgtgagct actggctcag
     6601 gaaagtaata ctccagttta ccgtatgggg gtggacgaac gtttcggtca ggtcggacag
     6661 atggattatc tattagagga ataccagctg acgccagcag ctattgagca gcaggttttg
     6721 aggattttag cggcagatta gctaaaaaag cctatcaggt gtaccacacc caaaaagctg
     6781 gaccttatag attaggattg agctttgtat gaaacagggt tcagtccttt tagttatgcg
     6841 ctttcagtcc ctttcactct gtaggcgtga aataatgatt gataactctt gatttcacct
     6901 tctaatttta atgtcataga aaaagttctt aagctttagg ttttatcttc acctttgggg
     6961 tgcaattctt ttgtcaggac tgatagggcc ttttgctatt actgctgagt ttttggcata
     7021 ttgtgagggc tgttttcatg aagctggaga agaatcgttt gatttcttag tgattgttca
     7081 gtttttatga ttaatcttac tgataaaagg accaaagcag ctaagcgttt actatctatg
     7141 ccatgcgata cgaagaatga gcttattttt gaacagaaag ttaatataaa acgagtattt
     7201 tgaacgattt tttggtaaaa tgtaagagat tacattatga ggagtaaaag ctagtcctaa
     7261 cataatggtt taatttaaaa aaggagcaat tcatgacaac atatcaagaa gatttttatc
     7321 aagccgtcaa tggtcaatgg gcagaaacag ctgttatccc agacgataag cctcgtacag
     7381 ggggcttttc agacctagca gatgagattg aggacttaat gctgaccaca acagatgctt
     7441 ggttggctgg tgagcatgtt cccaatgacg ctatattaga aaactttgtc aagtttcacc
     7501 gcttggttgc agattatgac aagcgtgatc aggtgggcgt agcgccagcc ttggacttaa
     7561 ttgaagaata caaggcctta ggatcttttg ccgagtttgc tagcaaggtg gctgattatg
     7621 agctaaatgg aaaaccaaat cagtttccat ttagtgtagc accagacttt atgaatgctc
     7681 agttaaatgt cctttgggca gaggcaccag gtcttatcct gccagatacc acttactatg
     7741 ccaaagacaa tgacaaaggc aaagagctgc ttgctatctg gcgtggcatg caagaggagc
     7801 tattgcctaa atttggcttt tcacatgaag aggttaagga cttgctggat aaggttatca
     7861 cgcttgataa acagctggca gattatgtcc tttctcgtga ggaatattca gagtatgcca
     7921 agctttacca cccttatgac tgggccgagt ttaccaagct agtgccagaa ttgcctttag
     7981 ataatatatt tactgtgatt ttaggtgaag taccagacaa ggttgttgtg ccagaggagc
     8041 ggttctggac agaatttgca gctgactatt attctgagaa gaattgggag ctgctaaaag
     8101 cctggctagt gcttacagca gcaggtgctt atcatgctta tttgactgac gagattcgtg
     8161 tgctatcagg agtttacagt cgtgccttgt caggaactcc acaggctatg gacaagaaaa
     8221 aagcagccta ttacttagca caaggaccat ttaatcaagc tcttgggctt tggtatgctg
     8281 gtgaaaaatt ttcaccagag gctaaggctg atgttgaaca caaggtagct aagatgattg
     8341 aggtttataa atctcgtctt gaaactgcgg attggcttgc accagcaaca cgtgagaaag
     8401 ccattacaaa gctaaatgtt atcaccccac acattggcta tccggaaaaa ttaccagaaa
     8461 cctatgctaa aaaggtcatc gatgataagc tatcacttgt tgaaaatgct cagaatttag
     8521 ccaaaatttc aattgctcat tcatggagca agtggaataa gcctgtggat cgtagtgaat
     8581 ggcacatgcc tgccaacatg gttaatgctt attatgaccc acagcaaaac caaattgtgt
     8641 tcccagcagc tattctgcag gcgccgtttt attcgttgag tcaaagctca tcagctaatt
     8701 atggtggtat cggtgctgtt attgctcatg aaatttcgca tgcctttgat accaacggtg
     8761 cttcctttga tgagcatggt agcctaaaga attggtggac agacgaggat tatgccgcct
     8821 tcaaggagcg taccgataaa attgtagagc aatttgatgg ccttgactcc tatggtgcta
     8881 aagtcaatgg taaattaaca gtgtctgaaa atgttgctga cctaggtggt gttgcctgtg
     8941 ccttagaggc agctcagtca gagccagatt tttctgccag agatttcttt atcaactttg
     9001 ccaccatctg gcgtatgaag gcgcgtgagg aattcatgca aatgatggca agtattgacg
     9061 tccacgcacc tggtcaatgg cgtactaatg tgaccttgac aaactttgat gaattccacc
     9121 aagaatttaa cattaaagaa ggtgatccaa tgtggcgtgc tccagaggat cgtgtgatta
     9181 tttggtaatc attgctcatt aaaaaaagac taagaggctt tgtacggccc tcctatcgtt
     9241 agaacgtata gtctagcttg tggaggaagg catgcttctc ttagtctttt tgtgttggat
     9301 aggctcgaaa agctcttttt ttaggcgtaa aaaaagattg aagatagctc ttaaaagctg
     9361 tcctcaatct tatgacttat gattagacta gttgttaagc gcagctgcca ttgtagcagc
     9421 aacctctgat tcaaagtcgt tagctttttt ctcaatacct tcaccgactt caaagcgagc
     9481 aaagctaatc gctttagcat tgactgagtc aaggtatgct tcaaccgttt tgctgtcgtc
     9541 catgatgtaa acctgagcaa gaagagtata ggcttggtca accttagtgt tatcaagcat
     9601 gaagcgatcc atcttacctg ggataatttt gtcccagatc ttttcaggct taccttcagc
     9661 agcaagctca gccttgatgt cttcttcagc ttgcgcaatc acgtcagctg ataattgagc
     9721 ctttgaacca tatttcaaga atggaagtgc tggcttgtta accattgcac gtgattcatt
     9781 gtcaagctca atagcgtggt tcaattgtgc caactcgtcc ttgataaatt gtgggtcaag
     9841 ctcagtgtat gataaaacag ttggcttcat agctgcgacg tgcattgata cttgcttggc
     9901 aagtgcttcg tctccgcctt caacaacagt gataacgcca atacggccgc cattgtgttg
     9961 gtaagcgcca aagtgttggt catcagtttt ttcaactagg gcaaagcgac ggaatgagat
    10021 tttttcaccg attgtagctg ttgcattgac ataagcatca gcaagtgttt caccagaagg
    10081 catgataaga gcaagtgctt cgtcgttatt agctggctta ccttctgcga tagcctttgc
    10141 agttgcgttt accaattcaa cgaattgagc gtttttggca acgaagtcag tttcagcatt
    10201 gacctcaaca acagcagcaa cgttaccatt aacataaaca cctgtcaagc cttcagcagc
    10261 aacgcggtca gcttttttag cggcctttgc catacccttt tcacgaagaa gctcaatagc
    10321 cttttccatg tcgccatctg tttcaacaag tgctttttta gcgtccataa cgccggcacc
    10381 agatttttca cgcaattctt ttacaagctt agctgtaatt tctgccattt ttatttcctc
    10441 caaaattaga atcggtcctc ttaaagctcg ctttagcaga gcctttgacc tgctgggttt
    10501 tcttacttaa aaaataacga gatagagcgg aatgctttgc cccgttagac catgttatga
    10561 atagcaagaa gctatcctag ttcaataagc ctgacttaag cttcgtttga accttcaaca
    10621 acctcaacga tttcttcgat tgactctgct tgagtatcag cttcaaatgc aacctctgcg
    10681 tcttcacctt gacggccttc gataacagca tcagccaatt tagcagtgat taatttgaca
    10741 gcgcggatag cgtcgtcgtt agctggaatg atcacatcaa tgtcatctgg gtcagcattt
    10801 gtatcaacca ttgccacaac tggaatacca agcttcttag cttctttaac agcgatttgt
    10861 tctttgtgtg ggtcaacaac gtacatcaca tctgggatac gaggcatatc ctcaatacca
    10921 cctaagaatt tttcaagacg tgcgcgttgc ttgttaagaa gtgcaacctc tttcttagga
    10981 agaacctcaa aggttccttc ttcttccatg cgtttgattt ctttcaaacg agcgatacgc
    11041 ttttggatag ttccccagtt tgtaagagtt ccacccaacc agcggtggtt gatgaagtat
    11101 tgacctgcac gagtagcttc gtcagcaact gcttcagcag cttgcttttt agtaccaaca
    11161 aacaagataa cagcgtcatt agctgctgca tcacgaacaa actcgtaagc ttgatcagct
    11221 aattttacag tttgttgcaa gtcgataacg tggataccgt tacgctctgt gaagatgtat
    11281 ttagccatct tagggttcca gcgacgagtt tggtgaccaa agtgaacacc agcctcaaga
    11341 agttgtttca ttgaaattac tgccatgagt agtttctcct ttatagaaat gtttttttcc
    11401 tctcttagac gtcggcttgc aactccacct gatggcaaca gaatcacaat cgatctaaga
    11461 tgagtatttg ttgtctgcac aactacaaca gtataccaaa aaaagctagt catagcaagc
    11521 ctaaatacac taaaacccac gtcgtacgca tgaggaaaat gcatgccatt attttctaac
    11581 catatgcatg ttttcaatgc atttttgata tgttgacgtt ttgacacgat ccatttttca
    11641 agcgcagctt agttttacta tcaatctttc tgaaaaagaa cacatgaatc atgaaaagat
    11701 atcagagaac ataagtttct tcaagcattt ggcgtacccc aaatgcttga tctatcagcc
    11761 ttgctgttta ttaggcctct aaaaagcaaa aaccagggta aacagttacc ttggtttttt
    11821 gctaacttac tgacgaatca ggtaatcaaa tgctccaata gcagcagtag cacctgaccc
    11881 catagaaata ataatttgtt tgtaggctga atctgtacag tcgcctgcgg caaagatacc
    11941 tggaatattg gttgaaccat atttatcaac aataatctcg ccacgatcgg ttaagctgat
    12001 accgctgtct ttgagccaag ctgtatttgg caccaagcca atctgtacaa agactccttc
    12061 aaggtcaaga tgcttttctt gattgctgtc acgctcgata tagttaagcc ctgtgacatg
    12121 atcgtcccca acaatatcct ttgtagcaac attttttaga atagtcatat tgtctgtttt
    12181 agcagcgcga tcctgtagca ccttgtcggc cttaagctca ggtaagaact caagaacata
    12241 gacatgctta gctaagccag ctaaatcaag tgcagcctca agtccagagt taccaccacc
    12301 gataacagca acgtttttat cttcaaagag aggaccgtca cagtgtgggc agtaggttac
    12361 tcctttattt ttaaactcat tttcgccagg aacattgata ctgcgccatt ttgcaccaag
    12421 cgctagaata gctgttttag ccttcaagac agcgccatta gcaagagtaa cctcaacaag
    12481 gtcttttttc tcaatcgaag tagccagctg ggctttgatg atgtcaacat cataggattt
    12541 agtatgctcc tcaacctggg ccataagctt tggtccctct gtatacaggg ttcctatcat
    12601 gttttcgata cctacagttt ccatgacttg accaccaaag gtctcagcca aaagacctgt
    12661 atttaagcct ttacgagcag catagatggc agcactattt cctgcaggtc ctccaccaat
    12721 gacaaggacg tcatagactc ctttatcagc aaaggcctcc ttagatagag gtcctgcgat
    12781 ttgctcaagc agctgctcaa tagtggcgcg accagaggtg aattcttctc cattcaaaaa
    12841 gacagttggc acagacatga tgccctttgc cttgacttcc tcttggaaca taccaccctc
    12901 aaccatagta tgtgaaatgt tcttattaag aacagccata atgttcaagg cttggaccac
    12961 atctgggcaa ttatgacacg ttaagctgac ataggtttca aagcttaaag gacggtcaat
    13021 agccctgatg cggtcaataa tatcctgctc aatctttggt gcacgtcctg aaacctgtaa
    13081 tagagcaagg ataaaggagg caaactcgtg acctagaggc agtccagcaa agatcactcc
    13141 gctgtcttga cctttttggg taatcttaaa gcttggttga cgtgttaggg tagtctcctc
    13201 aacagtgata cggtctgaca tggcagcaat ttcttcaatg aagtccttga ccttttgtga
    13261 gctatcgtca ctaccaagat aagcttgtag gactaagtca gattccaaaa gattaaggta
    13321 ttgagcaagc tgctctttaa tatcaggact taatgccata gcttttctcc tttgcctgct
    13381 taaattttgc cgacaaggtc aaggctaggt gttagtgttt cagccccttc tttccatttg
    13441 gctgggcata cttcacctgg gtgcttacga acgtactgag cagcacgaat cttatcaatc
    13501 aagctgcttg catcacgtcc gataccatca gcattgattt ccatcatttg gataacacca
    13561 tctggatcaa taatgaaagt accgcgttga gcaagtccat cctcaccaag aacatcaaag
    13621 gcttgtgaaa tagcatgtga tgggtcacca atcattgggt aagtgattgt tccgacaaca
    13681 tctgaatcat cgtgccatgc cttatgaaca aagtgtgtat cagtagatac agaataaacc
    13741 tcaacaccta aagattttag tatttcatat tgctcttgaa ggtcacctag ctctgttggg
    13801 caaacaaaag aaaagtctgc tgggtagaag caaacaactg cccatttccc tttaagatcc
    13861 tcattagtta cagtgataaa ttttccattg tgaaaagctt gggctgaaaa ttcagcaatt
    13921 tcctttccta ctaaagacat gtcatgtcct ccttttttac atttgatacc tgtattataa
    13981 gctaagaaat cttatctgtc cacttgtaaa ccctagattt atcaaggttt ttgatgttct
    14041 tttctaacaa tttcatatgt gaatttagtc acactgttta aaactattct aaataataga
    14101 aaactctgat aatatcaaag attcttgaaa ataagttttt gaaataattt taatattatt
    14161 aaaaatgatt ttctgattta aactctaaaa aataacataa accgaaaaaa ggagcagcct
    14221 gctaaaaaat agctgctatt tttatcttga cgaatgctat caactagggt aaaatagttc
    14281 ttgttatggc ggtatagcca agtggtaagg cacggctctg caaaagcttg atcgtcggtt
    14341 caaatccgtc taccgccttt tatatacaaa cgaatccttg attaacctcg taaaaacgtt
    14401 gttaaatcaa ggtttttatt ttttgtggca ggataaaaaa agagaaaaaa agaaataaag
    14461 tcggtcaaaa gtcggtcaaa tttccaaaaa tatcttttat ggcctgattg ttcttttctt
    14521 ttagcttatc tagctgatgg gcatatacct taagcgtaat gttcaaattc tcatgcccaa
    14581 gcaactgaga tatggatatt aggtcaacac cctttaagat taaaaaagat gcgtaagtat
    14641 gacgtagaga gtgattgcgt acaggacgac caacaatttt tttaaccaat ctattgcaga
    14701 gtgaattaga agctccgtag agcaccctat ttagcttatt ttcattataa taattttctt
    14761 taaatgctct aagcaatttt atagtttgct gatcaatggg aatttgtctt tttgattgct
    14821 cgttttttgt ttccttaaat tcttgagttt ttgagtaatc aaacgattta ttaatatcta
    14881 taaatccctt ctcaaagtct atatcgctcc aagttatccc ggtcgcttcg gcgaatcgta
    14941 gtccagtcac tgctatgatg tataaagtaa aataggaaac atactggtat ttctcactcg
    15001 ttactttgat tagatttaga tattcatctt cttcaaggaa atcaaattct tttgctctag
    15061 cttctttttg agattttaca atcgcacctt cggcaaaatt tgttttgata agcccatctc
    15121 taactgctac attaacagct ccttttattt gatagtggag tttttcgagt gtttcttggg
    15181 catatttttt ggcaaattcg ttgattgttt tttggtaaaa ggtatgcgtt acattattaa
    15241 gcttaatatc accaaaatat tttttgatgt gcttaagatt tttagtgtaa gtttcccaag
    15301 ttttatcgac aacatgcgga cgtttgtaga ttttagccca ttccttgcaa aaatcataaa
    15361 gtgatatatc atcaatatct ttatttagct cagcctcgac tttaatcgca gctgcagaag
    15421 ccaatgcttt tgtcttaaaa ccacctttgg atttttccct tttgttcccc tgactatctg
    15481 tgtagtaaat acgataagac cacttgtcgc cgcgttttct aaattttgcc attgttaatt
    15541 acctcatttt tatgttaaaa tgggtacagt aaagagacct actgcgaagc aggtttttta
    15601 ctatacagga tttgcctcac gctcagactc gccaaagttt gagagcgtgg ggcttttttt
    15661 aacgtttgat tttatagact gagcttcgat gctctatttt aaaaacttcg atgacaactt
    15721 cgtcatcaat aatctcagct aaaatacgat agtttcctaa acgataacgc cactctcctg
    15781 tacgattagc ttgtaaagct tttccgtatc tccttgggtt atctgtgcca tcaaggttag
    15841 tcattatcca ctgatagagt tgtttagcag tagatctatc taattttttg agttgttttt
    15901 tggctttttt agtaaacaat actttataac gcaaaaccta gctccttcgc tacatcttcc
    15961 atgctaaatc gtgtcccatc gtcctcagcc ttagcttttc tcaattcgta caaatcttta
    16021 gcatcttcaa tgatttccaa aaactggtca actgttagat tggaggtgtc aatgttattt
    16081 tctttgatgt aatctgcgat ataagcatcg tctttttcaa ggtttaatgt cattgcaatc
    16141 atagtatttt tctccttcta tatttctact ggtgtaaagc tgccgacgac atcatagatt
    16201 ttgatgtaag tatcttctgc tggcgggtag tcgataaaga tatcattgta ttttttattg
    16261 agagatacta atctaagccc gtcttcctct gtgtatactt ttttaaaata ggtctgtccg
    16321 ttatgcacaa ctatacatag ctgaccggca tatgctgaca tgccccgatc tacaatatag
    16381 agcatatctc cttgctcgta ctttggtagc atactatcgc cccgcactcc aattgcatag
    16441 tcgtagtgag gtggttcttc gtcagtgtag acagtatatg tgtcatattc atctgcttca
    16501 aatccacgac caaagccact tgcggctgcc gcgtaagtta cgccttgaac cgaaaataat
    16561 tcttcatgcg tagaaacaac tttattttgt tcttccaatt gctccttggc aaagtcaagg
    16621 actttttctt gtctaggttg ttctagttgg ttgtagatgg acactatttc agatgtattt
    16681 tttggggcat ctagcagaga cgaaaacacc tcgggtctga tacctaaagc tgagcaaatt
    16741 tttatggcat tctcgacgtt agcattcatt attcctcgct ctaatatcga gcgaaccgtt
    16801 gagtaaggca tgttgttttc ttctgcaaaa gattttacag agctataacg agaaagtata
    16861 agatgtttta gattttcttc attcatggct gcctctcttt ctgatttcat tataacacac
    16921 gatttttcgt ttgtctaaca aaaaaacact aagaaatacg aattttagta ttgacaaaca
    16981 cgaaaaaaag tattaaactt gtatcaagct cagatgagct taactttaaa accaaaaaca
    17041 cgaaaaatcg tgttagaaag gagttatatg ttaaatattg ataaagtgcg aaaagaaaaa
    17101 ggcgtagcaa tagtagacat ggctgatttt cttggcgtaa gagctcaaac agtaagcgat
    17161 aaattgcgcg ggacttacga ttttaaattt actgaggctt tggcgttgca acaaaaattt
    17221 ttcccggagt acgatttaga atatcttttt aacaaagcag tagacactgc ttaactttaa
    17281 aaccaaaaac acgaaaaatc gtgttagaaa ggagaaaatc aatatggtga caaaattttc
    17341 agaagaaata aaaatagtaa ggacgaagtc ttctgtttat gtaaacagcg tcttagacgt
    17401 tgcagataaa aaagaccccg cgtctgttgt agcagtcgca gagcttttaa aggcgtataa
    17461 gtcgttaaca gaattgtaat caactatggt gacttatata cgtgacttga tcgagattga
    17521 ccaaaacgat gtattgagcg tctgatagtt tcagttcaat aatatttgga ttatcagggc
    17581 actcatttgc aacttggcag aatgtgtgtt gcttaccatt tgtgaacatg attgtaatgg
    17641 tatcagtttc attcgctagt tgttcgataa tatatcgttt catacaatca cctcctttct
    17701 gctcatatta tagcagttaa ggacaactag agaaaggaca ctatgcaagc aaatcgaatt
    17761 ttttacggaa aagaaaaacc aacaaacgca gtagcgggcg attgctggtt tagagataac
    17821 gaattaatga tactcaagga caattgggaa gctagcgtaa acaacttaaa gagccctaaa
    17881 gttatcggag agatagaaat agacctagag cagcatgatg tactgctgac agccagaggg
    17941 aaccgtcctc cactattaat gattgatggg ataatgttgg gcggagtatc taaggtaata
    18001 attataaatg agttatccga gtcttgcgca attgtctctc ttaatgagta tatcaaggag
    18061 aatttgttcc cttttgacga ttttgaatca cttcaaaggt tatttcaaaa gggccatcag
    18121 aaattatccg tacgggaact ttgcttagaa aaacgtttag gtgagcattc ttatcaagac
    18181 catcgaaaaa gctgcgatga atagtaaaag ttttcttacc gctcgcaaga gctttctcgt
    18241 aatcctgagt cagtagttta acagagagat ctaattgata gtcgtacact tttgtttatc
    18301 ctccttccac taggataact acattataca acagaaagga acaacatgaa tcaactaata
    18361 aacatcaccc taaacgaaaa tcaagaacca gttgtcagtg gtcgtgattt acataaagta
    18421 cttgaaatca aaacagctta taaagattgg tttccaagaa tggctgaata tggttttgaa
    18481 gaaggtcagg actttagctc atttttgagc aaaagtacag gaggtcgtcc tagtcaagac
    18541 cacgttctaa aactagacat ggcaaaagag attgctatgt tacagcgtaa cgagaaatct
    18601 aaagaagtcc gtaaatactt catccaggtc gagaaagact tcaacagccc agagaaaat
//
LOCUS       DARYXZ010000044        18402 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYXZ010000044 DARYXZ010000000
VERSION     DARYXZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18402
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            174..554
                     /locus_tag="TV186_001511"
     CDS             174..554
                     /locus_tag="TV186_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1532894.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            554..1402
                     /locus_tag="TV186_001512"
     CDS             554..1402
                     /locus_tag="TV186_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1532895.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            1502..2713
                     /locus_tag="TV186_001513"
     CDS             1502..2713
                     /locus_tag="TV186_001513"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1532896.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            2706..4573
                     /locus_tag="TV186_001514"
                     /pseudo
     CDS             2706..4573
                     /locus_tag="TV186_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            4678..6423
                     /locus_tag="TV186_001515"
     CDS             4678..6423
                     /locus_tag="TV186_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532897.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISIPKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKSYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            6423..8199
                     /locus_tag="TV186_001516"
                     /pseudo
     CDS             6423..8199
                     /locus_tag="TV186_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            8340..9689
                     /gene="gdhA"
                     /locus_tag="TV186_001517"
     CDS             8340..9689
                     /gene="gdhA"
                     /locus_tag="TV186_001517"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1532898.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            9821..10231
                     /locus_tag="TV186_001518"
     CDS             9821..10231
                     /locus_tag="TV186_001518"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1532899.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(10422..12428)
                     /locus_tag="TV186_001519"
     CDS             complement(10422..12428)
                     /locus_tag="TV186_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1532900.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            12877..14598
                     /locus_tag="TV186_001520"
     CDS             12877..14598
                     /locus_tag="TV186_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532901.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            14600..15763
                     /locus_tag="TV186_001521"
                     /pseudo
     CDS             14600..15763
                     /locus_tag="TV186_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            15915..16691
                     /locus_tag="TV186_001522"
     CDS             15915..16691
                     /locus_tag="TV186_001522"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1532902.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            16684..17649
                     /locus_tag="TV186_001523"
     CDS             16684..17649
                     /locus_tag="TV186_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1532903.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            17745..>18402
                     /locus_tag="TV186_001524"
     CDS             17745..>18402
                     /locus_tag="TV186_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEL1532904.1"
                     /translation="MDEIKLYENKEIRSIWDEEKEEWYFSVVDVVGVLTEQENVRGAS
                     TYWAVLKKRLKEEGNELLTICKQLKMKATDGKMRLTDVADMQGIFRIIQSIPSPKAEP
                     FKLWLAEVGKERIDEIIDPELTIDRALETYLKKGYTREWINQRLQAIQVRKELTDAWD
                     DHGIQKGKEYAILTDEITKAWSGMTTRGYKNLKGLKKENLRDNMTTLEIVLNMLAEAT
                     T"
BASE COUNT         5477 a         3260 c         4299 g         5366 t
ORIGIN      
        1 cttggggtgt ttttttgttg taggagattg attggttgat agaaggcagg tttatattta
       61 ttgaagtgac aaggtctgga aaaaaattat ccaaaatact ggtttaagtc tactttaata
      121 ttcgtcaaat ctatgctata atgggtcata tcgccattaa ggagaacgaa atcatgcaat
      181 tagtacgtga aaaagaattt gtcaatcagt accattatga cgccagaaat ttagaatggg
      241 aaaaagaaaa tggaacaccg gaaacaaact ttgaagtaac ctttcagttg attaataaag
      301 atgtggaaaa taaagagacg gctattgttt ctgttttaca atttgtcatt gtcaaggaag
      361 agtttgtgat tagtggtgtg atttcacaga tggttcgtat tttaggacgc ttggtggata
      421 agcctagtga atttacacaa gaggaggtcg aatccttggc tgctccatta ttagacatgg
      481 tgaagcgctt gacctacgaa gtgacagaaa ttgccttgga tcgtcctggt attaatttgg
      541 agtttaaaag ttaatgaagt tagcaataat aactgataat acagctcacc ttccagagca
      601 gttagcggag catgccgata tttttgtatt agacatacct gtaatcatag atggtcaaag
      661 ctatgtcgaa ggacaaaacc tgaccattga agccttttac caaagcatga gagaatctca
      721 agagctgcca aaaaccagtc agcccagcct ctctgaatta gatgatttac tagggcgtct
      781 gtcaactgag cactatactc atgtgattgg cttgttcttg gctagtggta tttcaggatt
      841 ttggcaaaat attcaatttc tcatcgagga gcaccctgag ttgaccattg cttttccaga
      901 tagtaaaatc acctcagcac cattaggcag catggttaga aatgctttag agtggtctca
      961 gcaaggcttg agctttgcag agattatgga taagctagaa gagcaaatcg ctggaaccac
     1021 agcctttatc atggttgatg atttgaatca tttggtcaag ggaggacgct tatcaaacgg
     1081 ttctgctttg ctgggaaatt tgctcagcat caagccaatt cttcgctttg atagtgaagg
     1141 aaagattgtc gtctatgaaa aggttagaac ggaaaaaaag gccatgaagc gcttggttga
     1201 tatcttaaag gaattgacag ctagtggtca gtacgaggta tcaattatcc atgctagagc
     1261 gcaggataag gctgatatct taaagcagct cttgttggat aatggctata cctgccctgt
     1321 tgaggaggtt cattttggtg cagtgattgc agcccatctt ggagaaggag ctgttgcctt
     1381 tggcataacg cctcttgtct aaagaggctt gcccatgacc aatctgagct tgatatgaca
     1441 gcctttaacg ggaagcatat gacaaggctc taggagcttt taggtggtag attaaaacat
     1501 gataacatta atgacaatgc cttctgaatt tcagaaggct ttaccaatag tgaaaaaaat
     1561 caagcaggct ggctttgagg cctattttgt tggtggaagt gtgagggata gcttattaaa
     1621 caggcctatt catgatgttg atatagctgc tagctgctat ccagaggaga caaaggctat
     1681 tttcttaaga acaattgatg ttgggattga gcatggcaca gtgcttgttt tagaaaatgg
     1741 cagtgaatat gagatcacaa cgtttcgaac tgaggacgtt tatgtggatt ataggcgccc
     1801 tagtcaggta tcctttgttc ggtccttgga agaggattta aaacgaaggg attttactgt
     1861 caatgctctt gccttagatg aggacggaca ggttattgat atctttaatg gcttagagga
     1921 cctaaagcat aagcttctaa gagctgttgg aaggcctcag gagcgctttg aggaggatgc
     1981 cctgcggatt atgcgaggct ttcggtttgc tgccagctta gattttgata ttgaggctga
     2041 gacctttgaa gcaatgaaaa gccatgctcc cttgctggag aagatttcta ttgagcgctc
     2101 ttttattgag cttgataagc ttttaatggc cccaaaatgg cgtaaaggta tcttagctat
     2161 ggtggcatgt caggccttta actatttgcc aggcttagtg ggcaaggaag aagccctgca
     2221 aaagtacctg aaaaccttag cagcggatta tgtgtttcag gacaatcatc aggcttgggc
     2281 ctatttgctg gttatgctgg agcttgatca gcctaaagcc tttttaaagg cttggaaaac
     2341 ctctaatgat tttcagcgta gggttacgat gatggcctct ctttatcaga ttcgccaaga
     2401 aagacagcta gaaaaatggg atatttactc gtttggcaag gacttggctt tactcgttga
     2461 cgatttacga caggcacagg gcttggtcag tgaggccaag cgtgttgaga gcttgtatca
     2521 ggagctgacg atccatgata agcatgatat tgtggtcaat ggctcttatc tgattcgtga
     2581 gcttggaatg aagccaggac cacagctggg aatgctttta aatcagattg agcaggccat
     2641 tgtagagggg cgtctcgtca atcaaagaga acacattgag gcttttgtta gaagggaact
     2701 actaaatgag tgattttatc gttgaacatc tgacgaagtc tgttggagat aagaccgttt
     2761 ttcaggatat ttcctttatt attcatgctg gtgatcgcat tggcattatt ggtgtcaatg
     2821 ggacaggaaa aacaaccttg cttgatgtta tttctgaaaa agtgggcttt gatggtgacc
     2881 gctcaccttt ttcaaaggca aatgactatc gtatatctta tttaacacag gagccggact
     2941 ttgatgatga tcagtctgtt ttagatactg ttctgtccct agaattaaag gaaatgcagc
     3001 tgattcgcca atatgagctg ttgatggctg actattcaga tagcaatcag gaaaagctag
     3061 cagaggtgat gactgagatg gatcgattag atgtttggtc gatcgaaagt gaggttaaga
     3121 cggtcttatc aaagcttggt attgtcaatc tggatcagag agtgggtgac ctgtccggtg
     3181 gtatgagacg tcgggtacag ctggctcagg tcttgcttgg agccagtgat ttgttgctgc
     3241 tagatgagcc gaccaatcat ttggatattg ataccatcgc ttggttaagt cattacttaa
     3301 ggacctctaa aaggactgtt ctatttatta cacatgatcg ctattttttg gatagtatag
     3361 ccacacgtat ctttgaattg gataaggctc atgtgactga atatcagggc aattaccagg
     3421 attatgtgcg tctgaaggct gagcaagacg agcgcgaagc agctcatttg cataagaaaa
     3481 agcagctcta taaacaggag ctggcttgga tgaggacaca gccacaggcg cgtgcgacca
     3541 agcagcaggc cagaattaac cgctttgaac agttaaaaaa ggaccttcat caggaaaggc
     3601 ctatagatca attagatatg gcctttgaag ccagtcgtat tggcaagaag gtcattaatt
     3661 tcaaggaggt ttcctttgct tatggtgatc aggccattat tgagcatttt aacctgatca
     3721 ttcaaaataa ggaccgtatc ggcattgttg gagctaacgg tgctggaaag accaccctgc
     3781 ttagcttgat gactggtgac ttaaaaccaa cagctggtca gctagagatt ggcgagacga
     3841 tccgtattgg ttatttttca cagcaaatca aggatatgga cggcagcaag cgcgtgatta
     3901 gctatttgca ggaggtggca gatgaggtca agaccagtgt tggcaccact agcatcagtg
     3961 agcttttgga gcaatttctt tttccgcgtt ctagtcatgg ctccttaatc gctaagctat
     4021 caggcgggga gaaaaaagac tgtatttgct aaagctcttg atcgaaaagc ccaacgtcct
     4081 gctgctggat gagccgacca atgatttgga tattgcaacc ttgacagtgt tggagcattt
     4141 tttagctcaa tttgctggtc cggtcattac agtgagtcat gatcggtatt tcttggataa
     4201 ggttgcaaca aaagtattgg cttttgagca tggagctatc agagaatact atggtaacta
     4261 tagcgactat ttagatgaaa aggcttttga agcagaggtc atagagcctg ctgtcagtga
     4321 gcaaaaagct ggcactgacc atcaggtcac ctctaaaaag agaatgtcct atcttgagaa
     4381 aaaggaatgg gcagctattg aagaaaagct agctgctatc gagcaacaaa tagctactat
     4441 tgaggagcaa atgctcagag cggcaagtga ttacgaccaa ttggcacaat atcaaaagga
     4501 gctggatcag cggaatcttg agctgcttga agcctatgag cgctttgatt acctaagcga
     4561 attagaagaa taattaatta tgtgtcaatt tcatattttt gtgttaaact agttatagac
     4621 aaaaagaagt gctagcttgc gcttcttttc atatcactat tatttgggag gaaatgaatg
     4681 gctttaattt ggtcctattt aaaaacaaga cctaaatgga tttgtttcga tattgtgggt
     4741 ggcttgttat ttgttctggt caatctgggg ctaccaacaa tattggctcg tatgattgat
     4801 caaggcgtta tgcagcagga tcaaagggct ctttattttt gggctctgat gatgtttatt
     4861 atcgtacttt taggtgtcat tggacgggtg attttatcct atgcttcggg taagctaacc
     4921 accaacatga tcaaggattt acgtaatgac atgtatagct gcttgcagga ttattcgcat
     4981 tcggaatatg aaaaaattgg catagcctcc ctggttactc ggataacaaa tgatgccttt
     5041 gttttgatgc aatttgctga aatgtccttg aggctgggtg tcgtaactcc tttgatgatg
     5101 atcttttcag tggtgatgat ctttttaacc agtccatcat tggcttggat tgtggctgtt
     5161 gccatgcctt ttttagttat tgtggtgctt tatgttgcga taaagacaag acccttatca
     5221 gaaaagcagc aggagagcct tgatcgtatt aaccaattgg tgcgtgaaaa cctgacaggt
     5281 ctgagagtta ttcgagcctt tgcaagagaa gactttcaag aagagcgctt caataagcgc
     5341 aatgatcact attctggaat ctcaaagcga ctatttacct tgacaggctt aacagagccc
     5401 ttatttgtgc aaattatcat tgctatgatt gtggggatcg tctggtttgc cttggatccc
     5461 ttggcaaggg ggcagtttaa gattggtgat ttggtggcct ttatcgaata tagctttcat
     5521 gctctttttt catttttaat gtttgccaac ctctttacca tgtaccctaa aacagcagtg
     5581 tcaagcaagc gtatcaagga agtgctggat atgccgattt cgattcctaa aaatgaagat
     5641 ggtataacag cgttcacaac acgtggttat ctagaatttg ataacgtgac ctttgcctat
     5701 ccgggtgaaa cggaaagtcc agttttacat aacatctcat ttaagactag gcctggagag
     5761 accattgctt ttatcggctc gacaggttca ggaaaatcat ctttggttaa tctgatccca
     5821 cgattttatg acgtgacctt agggagaatc ttggttgatg gcattgatgt cagggattat
     5881 caattaaaag cgctgcgttc taaaatcggc tttattcctc aaaaagccct gctatttaca
     5941 ggaaccattg aggaaaacct aaaatatggt aagtcagatg ccagccacag tgagcttgag
     6001 caggcaacag aggtttccca agcgaaggac tttattacca gtcgtgaaaa gagctatcaa
     6061 acccatctag ctgaggccgg cagtaatcta tcaggagggc aaaagcagcg cctgtctatt
     6121 gccagagcag tggtcaagca gccagacatc tatatctttg acgattcctt ttctgcccta
     6181 gattacaaga cagatgctga attacgcaga cggctgaaag aggtgacaca agatgcaacg
     6241 gtcttaattg tggctcaaag ggtgggcacg attatggatg ctgatcaaat cattgtcttg
     6301 gatcagggag aaattgttgg ccgaggtaca catgaggaat tgcttacaag caatgccatc
     6361 tatcgtgaaa ttgccaattc tcagctaaac aaggaagaca tgacaaaaga ggagggggat
     6421 taatgactga aaagcatgtg tttagaagaa tttggaccta ccttagtgcc tataggctct
     6481 cactaataac tgccattatt ttaaaaatag tcagtgctgt gatgagtgtc ttagagccct
     6541 ttgttcttgg cttggtgata acagagctat ctgcaaacct attagacata gcaaagggag
     6601 tctctggtgc aggcattaat aaaacctata tcgcctttct tttagctctc tatatcatta
     6661 gggcccttgt ttacgagtta ggctcttatg gttcaaacta ttttatgaca agggctgtgc
     6721 aatcaagcat ttgtgatctt cgtcgagacc tcagtcaaaa aattaatcgt atccctgtgt
     6781 cttattttga taagcatcag ttcggcgata tgctaggccg gtttacctct gatgttgaga
     6841 cagtctctaa tgccttacag cagtcctttt tacagattgt taacgccttt tttaccctta
     6901 ttttggtggt tggcatggtc ttgtatatta atgcccccct agcctctgtt gtgattatcg
     6961 ctatcccgtt gatatatgct gcttctcgat ttgttttaaa aaaatcacag ccttatttta
     7021 aagcgcaggc taatattttg ggagaaatga atggctttgt gcaggaaaat ttgaccggct
     7081 ttaatatttt aaaactgtat ggtcgtgaag aagcctcaaa ggaggaattt caccagatca
     7141 ctgagcgatt acaagaagta ggctttaagg ccagctttat ttctgggatc atgatgccag
     7201 ttctgcattt tatttcagat tctgtttaca tgattgttgc cttaatcgct ggcttacagg
     7261 tgatagcagg ccgcctgaca atcgggaaca aacatgcaag cctttgttca gtacatttgg
     7321 caaatcagtc agcctattca gaccataaca cagctggctg gtccactgca aagtgccaag
     7381 tcatccttag aacgtatctt tgcagtgctt gatgaggcag atgaattgac tattgcccaa
     7441 gagcatttag aacatgattt aacaggtcag gtgtccttta atcaggttga ttttagctat
     7501 acagcagaca atcctctgat tagaaatttc aatttagagg ttaagcctgg tgagatggta
     7561 gctatcgttg gtccgacagg agccggcaag accaccctga ttaatttatt aatgcggttt
     7621 tatgatgtga atgagggctc tatcacagtt gatggtcagg acattcgtca gttgtcacgt
     7681 caagcctata ggcgtcagtt tggtatggtg ctgcaggacg cttggctctt tgagggcagc
     7741 attcaggaaa acttgcgctt tggtcattta gaggcgactg atgaacaaat aattgaggct
     7801 gctaaggctg ccaatgttga tcatttcatt aggacattgc caggtggcta tcatatggtg
     7861 atgaatcagg aatctagcaa tatttccctg gggcaaaagc agctgctgac cattgctcga
     7921 gctctcttag cagatccaaa gctgctaatc ctagatgagg ccacctcgtc tgttgataca
     7981 cgtttagagc ttttgattca aaaggcgatg aagcgattaa tggttggcag gactagcttt
     8041 gttattgctc accgcttatc aaccattcaa gaggcggata agattttagt tctaaaagat
     8101 ggtcagatta tcgagcaggg gaatcatgac agcctattag ctgctaaggg cttctattat
     8161 gagctttatc atagccaatt taagaccagt cagtcttaaa aagcttaggg tcttggaatg
     8221 aatcgttcca aggctctttt aatttgcttt agatcatagt aaaagcttga catcaaaatt
     8281 cagaaaattt ataatattga ctatacttaa aatagaatga agaagcgaga ggatatataa
     8341 tggtatcagc aaaagactat gtagccagtg tttttgataa ggtcaaaagg gataatccgc
     8401 atgagactga atttcttcag gcggtcaagg aggtatttga ttccttgatt cctgtttttg
     8461 aaaaataccc taattatatt gaggaaaatc tattagagcg cttggttgag cctgagcgtg
     8521 tgatttcctt tagggtgcct tgggttgatg accagggcag ggtccaagtt aatcgtggct
     8581 accgcgtgca attttcatca gctatcggtc catataaggg agggcttcgc tttcaccctt
     8641 ctgttaacca gtctatagtt aaatttcttg gctttgagca gattttcaaa aatgctctga
     8701 ctggtcagcc tattggagga ggaaaaggag gatcaaattt tgatcctaaa ggcaaatcag
     8761 acctagaaat catgcgcttc acacaaagct ttatgacaga gctgcaaagg catattggac
     8821 ctgaccttga tgttcctgct ggtgatattg gtgtaggggc tcgcgaaatt ggctatttat
     8881 ttgggcaata taagcgtctt aatggcttta agaatggtgt gttgacagga aaaggcttag
     8941 cttatggtgg ctctttggct cgcacagagg ccacaggcta tggtgtggtt tattttgctc
     9001 agcaaatgct ggcggctaag gggcaggact tggctggtaa aacagctatt gtatctggat
     9061 caggaaatgt tgccatttac gcaacggaaa aattgcaggc cttaggtgtt aaggtattag
     9121 cagtgtcgga ttcctctggt tacgtttatg atgataaggg cattgatctt gagaccctaa
     9181 agcaaatcaa ggaagtgaag cgtgagcgta tcaagaccta tctagagagt cacccggctg
     9241 ctgtgtttac accggctggt gagggatcca tctggactat taaggcagac cttgcctttc
     9301 catgtgcgac tcaaaatgag ctacaagagg cagatgctaa agccttgatt gagcatgggg
     9361 ttaaagctgt tgtcgaaggg gctaacatgc cctcaacctt agaggctatt gagcaatttc
     9421 agcaggctgg ggttcttttt ggacctgcta aagcagcaaa tgctggcggt gtagcagttt
     9481 ctgcgctgga aatggcacaa aatagcggac gtaccgcatg gacctttgaa gaggtggatc
     9541 atcgattgta tgacatcatg aaggctattt atcaaaaagc agccgctgcc gccaaggaat
     9601 gtggtcaaga aggcaaccta gtggtgggag ctaatattgc aggctttctc aaagttgctc
     9661 aggccatgtc agcacaggga atcgtttaag agctgtggct ggtatatgct gaatatatca
     9721 gtagggttag cacattaatc ttagctcaat gacgttaaga tatacgatcg gtcatctaga
     9781 caatgcatgc cgattagagc aatgaatcaa ggagaagctg atgatcaaaa aaatcgtgaa
     9841 ggacaccttt ttcttgcagc aaaaagcaca gccagcaacg aaaaaggacc tttggattgg
     9901 tcaagacctg caggatacct tagcttatta tcgtgatagc tgcctggggc tggctgctaa
     9961 tatgataggg gaaaacaaga gggttattat tattagcatg ggctttgtgg atttggtgat
    10021 gtttaatcct gtattaattg ctaagcgtga agcgtttgag gcagaggaat cctgcctatc
    10081 actaatcggc caacgtaaga caaagcgtta tcaggagatc aaggttgatt accttgatgc
    10141 acattggcac aagaaatccc tgagattgac aggcctgcct gcacaaatct gccagcatga
    10201 gctggatcat ctggagggca tattgattta aatcatgacc acccgttagt gaactgcacc
    10261 ccaaaagtta gacagaaaat ctaacgaatg agggcagtcc atagatgggt ggtttatttg
    10321 tcttgctcaa caggtgcgaa acaaataaac gtcacataaa tcagaaaacc ggctgtatgc
    10381 ttaagataca gtcggttatt gctgttatgg ctaggacgat tttattggcc ttcctttttc
    10441 ttgaaaaggc tagtaccagt taaggttagt agtcctagga ttgtcatggc agcagcagaa
    10501 tgctggcttg ttcctgttgc tggtaaggca gcattagctt gctttttagc tgctagaggc
    10561 ttgatgcttg tggcaggatt agcattttga gcaggcgtaa ataggtcaga gacaagctca
    10621 gtagcaagca ccttgccctc acgattctta aagacgcggt tgatgatctc gtgcttgccg
    10681 gtatgatcac tttgagtaga gccttcaaga ctggcagtga cataggtttt cacaccgtta
    10741 ataccagcac ttacagtctt tccagctgct tcaaggtcct tgatgtattc gataaagacc
    10801 tcagtatcag gattaatggc tcctagtagc ttagcgtcct taaagacgga gaagccatca
    10861 ccaccgccat ataggaagtc gttgatgatt agggtgtatt gagctgctgg atcaatttct
    10921 tcaccattat ctttataagc ctttactacc ttaaacggtg ttgaaggatc gttagcctca
    10981 ttagctgtat aagtgtattt gagtccagac atttgaagga agtatttttg gtcttcatcg
    11041 tattgttggt tcaagacatc atagatttgt tggccagtca tttgaacgac ctgaagaata
    11101 ttgccaaatg gttgaacagc ctgtgcagct ccccaggtaa tggtttgatc ctctttgacc
    11161 accaagtcag cgcgaatacc gccattattt gtcatggcaa aatcaacatg agggaaggtt
    11221 tttctaccaa tggttaattg ggcagttgtt atcaaattgc caacaggaga ttccttgtct
    11281 tcgttttctg ttttagaaat cgttgaagag gtagctgctg taccgatctt tagctcggta
    11341 acggttttga caatgtcatt ggcttgatca acaatggctt gaatgtcggc attgcctgtt
    11401 tttatgccag gagcaacggc aatgaccttt gcttcaggag tggctacaaa atcattgagg
    11461 tcagtgtcta gtgttccacg aacatctgca taggctttcc cctgtgaaac agcctgaacg
    11521 acacgtgttg tgccaatggt accgttggtg tattggtggt tgtgaccagc aaagacaata
    11581 tccacactat gctcaggata aagctggtta accttttcca taactgctgc catctcatca
    11641 tgaactaccc cgttatcact tgttgctggg atatgagcta ggacaacaat cgcattgacc
    11701 tgctgctctt ggagctcttt agcatattta acgatggttt ctgcagagtc taggtaatca
    11761 tattgttcat aattttgttt taggacaagg tttggaattt ctgttgtcac aacaccgata
    11821 aagcccacct tgactgactt atcattaact gggacttctt tgacagcata aggcttccag
    11881 ccaaaaggaa tcgtgttggt ctccttgtca acgacatttg caatgacaag ggtttgattt
    11941 gaagcttcat gctcgtattg cttagtaatg tcgttgatag ctgagtcttc agcaggtgca
    12001 gtgcctgtca tgatacggtt gaattcagct aagccctcat cgaattcgtg attcccaagg
    12061 gttccgtatt caaagcccat ctggttgaat accttaaccg ttggctcgtc ctgtaatagt
    12121 ccagaattag caggactagc tccgaccata tctcctggtt gaacacgaat gcttgtccca
    12181 tctgggcttg tttgcttaaa gtcagcctct gcatcgtcca gataagcagc taattgtgct
    12241 gcggtaccag cgttagatac ctttccttct ggcatgtagg cagagccggt tgtgtctaag
    12301 gcaccatgaa agtcattgac accaagaaat tgcacgtcta cctgatcggc ctgcacgccg
    12361 gttactagca tagaaactcc ggcaaagaca ccaagaacac tactttttaa aacaaaatgc
    12421 tttttcataa acgctcctaa aagtttaaag tattgtcaca agttaagtgt actattattt
    12481 aaatgagaat tcaacaaaaa ttaataaaaa agctaacaaa aattcaacga tagcgtttgc
    12541 taatcactga aaacgtttaa aatgcaaaca ttggaagcgt tttttgtaaa aaaatagaag
    12601 aactatccaa aaaaggcttt acaagcccag tattctatga taagatgtta ggcagattaa
    12661 aagaaaggag aaattaataa tgatccgttt cattcaacta tttaaccatt attacgatag
    12721 tctcctttct aaccaaaaca gttagtttct tttagtttca ctaaatagaa atagtagagc
    12781 ccgcggtagg aaggatatct tattgcgggc tttttgtgtg caaaaatcct attttaagac
    12841 agcttgaaat aggttagttc agaaatggag gatatgatgc tgaccttaat tgttcaacat
    12901 attaagcaaa agaaatggat ttatatcctt attgcaatga ctttagtgat atatgatgcc
    12961 tcacttgtga taccaacaag ggttattcaa gacttggttg atttgatgtc aaggcatcag
    13021 ctaagctcag gggcattggt gaggcatgtt atcattcttt tggctacggc agtagtgtct
    13081 tatggggttg cttatttgtg gcatcttcat ttatttcagg aggcagttca ttttaagttt
    13141 gatattcagc agcgtgcctt tcgaaagctt gtttttatga gaacgccttt ttatgagaaa
    13201 tttcgctcag gtgacatgat cacgcgtttt tcaacagatg tcgaagcact tatggacctt
    13261 atcggctatg gcttgatgat tatcctatat gctggtggta tgattgcttt tattattccg
    13321 accatgtttt tgatttcttg gaaaatgacc ttgataggaa tagtaccgat tttgcttatg
    13381 atggtgatga tctatggtgt gacgaaaaag caagagcatt tggttgaaga ggcgcgtgag
    13441 gcgatttcaa gccttagtga tgaggtacta gaaaccgttg agggcattag agtgatgcgt
    13501 gcttacagta aaaaagatta tttggcactt cattttgctc aaaagactca gaatttggca
    13561 gataaatgga atcaggtggc caagtatcgt gccttgtact ttcctcttta cagcgtcatg
    13621 attgccatta gtacagtaat cattttaatg gtaggcctac agctcatagc aagctcagag
    13681 gtaacacttg gtcaagtcat tgcgctgcag ctttatctgg tgtctttggt ggagcccttt
    13741 ggcatgctgt cagactttat tttggtttat cagacaggaa agacctcttt tggtaagatt
    13801 aatgaactca tcgaaacaag tgatgatatg gagcctgatg gccagcttga gttagagagc
    13861 tttgatcaga ttgcttttat agactatagc tttacctatg ccaatagttc taggcctagc
    13921 ttagaaaaga tcaatttaac cctgaaaaag ggacaaacct tagggattgt tggtaaaaca
    13981 ggctctggta aaacaaccct tgtcaggcag tttttgagac aataccctct tgggcagggg
    14041 cagctgatga ttaatcatcg tagtgtcttg gattataagc gtcaatcact tgagcgtcaa
    14101 attggctatg tgccacagga gcatatcctg ttttcaaaaa cggttgctca aaacattgcg
    14161 atggggaaaa aggcagctac aactgaggaa atcttggagg cgattgaaac tgcggccttt
    14221 acgcgtgatg ttcaaggaat ggcaaagggc ttggatactg agattggaga gcgtggtctg
    14281 tctatttcag gaggtcaaaa gcagcgtatt tcgattgcca gagccttttt gtcccagcca
    14341 gatttgctga ttttagatga ttccctgtcg gcagttgatg ctagaacaga gactgatatt
    14401 attcgacaca ttcaagacga aagaaaggga aagacaacac ttattgttag ccatcgcttg
    14461 tctgcgattc agcatgccga ttgggttatt gttctggatc aggggcagat agtagaggaa
    14521 ggtcagcccc aacaactttt agctcagaag ggctggtatt atgaacagta ccagcgtcag
    14581 caggctcagg aggtttaaga tgaccctatt tataaaatta ataaaagaaa ttaaagctgt
    14641 gaccttggct ttttccctgg caataggctt tttgctagtg gcaacagctg gaggtcagat
    14701 ggctccctta ttgttgcaac aaacgattga tcattacttg actccgatag ctagaggaaa
    14761 agaggtaccg attgaaggct ttcagcgctt gctcctgctg tatttgctgt taattgtgat
    14821 aacagcagtt ttgcgttata tctcttatcg aatgctggtt tattcctcta ataggatcgt
    14881 tgctaatctt cgtaatcgag cctttgatgt catgcagagg ctgccgatag cttattttga
    14941 tcatcagcct gcaggaaaga ttgcaactag gattgttaat gatactgaaa ccctgaagaa
    15001 tcaattttat gataaccttt tgtctcaaat tattgtcagt ctttcacaaa ttatttttat
    15061 ttatgtggtg atgatttacc ttgatgtgaa gtcaggcttg ctgttgctgc ttattatgcc
    15121 actcttttat ggcatgcaat ggctgtataa aagcttgact gaccagccaa tgaaggattt
    15181 ttatcaggct aggagcgctg tcaacacaca agtcaacgaa accatgaatg gtgtttctat
    15241 tattcagctt tatcatcaag aggatacgat cttagaggaa tttgaagagc agatccacca
    15301 gatgaaaaca gctgatgata ggattatttt tgcagagtca gttgcttcat ggaccctgac
    15361 ggaattggta aagtatggca tgattgccgc tattttggct gttattggtt accagttctt
    15421 gcaggggaga tcaggcatca cagttggtaa gctctttatt tacgtcaatt atttgctgcg
    15481 cttgtttgat ttattaagta tgctggttag gcagctacct aatattcagc gctcaacagc
    15541 gacaggaacg cgcctaatga agctgcttga ggcgcagaca gagccggata aagcacgagc
    15601 aattgagcta acagatggta ctgtggattt taccaaggtg tattttgctt acgaaaatgg
    15661 caagacagtt ttatctgata ttaccattca tgctgataaa ggggagacgg ttgccctagt
    15721 agggcatact ggctctgggg acaatgctat aatgatgata gtacaataaa tccaagtaaa
    15781 atcaatggtt aaaggcttcc gcaaaacttt taaacttgat gatggattga ggctatcatc
    15841 tttttttata tctaaaatta tataaaagta tagcataaaa tgaaatctct gtatagagaa
    15901 gaaggaggga ctttatggca gaagtgataa ccatagccaa tcgaaaaggc ggagttggaa
    15961 aaacaactac aactctaaac cttgcctatt cactaaaaga actggggaaa aaagtattag
    16021 tcattgacct tgatccacaa gctaatctta caagatgttt tgatatggga aatacagaaa
    16081 atataaaaac catagggcat ttgttaatgg tagaactgga ggaagaagaa agctatttgg
    16141 tagagggcta taccaaatct tatgatgaga tagatattat cccctcaagc attttcttat
    16201 ccgccgttga aacacaaatg agagcagaaa caggaagtga acgtatatta tcggaaatta
    16261 ttaggagggt aaaagagaat tatgactata ttctcataga tacatcacca tcacttagtg
    16321 ttttgactat aaatgctctt tgtgcctcag acagtgtcct tatagtagcg gatacacagc
    16381 tgttcgcagt tgttggaatc aatgaacttt taaaaactgt tcaaaaaata aaaaagagag
    16441 tgaatccgaa actgaaagtg caggggattt tactaaccat gtgtgagaat agaaccaatc
    16501 tgtccaaaac actgatggag caagtagaag aaatgttcca aaagaaaatc aaggtctttc
    16561 aaaccaaaat tccgaaaaca gttaaagttg gggaagccat ctatagcggg caaagcataa
    16621 aaaaatatgc aaaaggcagt agtgtagaca ttgcctatga caatctggca aaggagatct
    16681 gctatgagta aaaaacttct aaagagagaa atcaccgatg ccgtagattt tttgcttgat
    16741 gatggaaatg ccttggaaca aggaaatata cagaatatag aacttgattt gcttgaaaat
    16801 tatcataatc atccgtttac tttatataca ggtaagagat tagacgatat ggtagagagc
    16861 attaaggaaa acggagttct taatccaatt atcgtcttga aaaaagataa caactatgaa
    16921 atactttccg gacacaatag agtaaatgca gcaagaatta caaaaataaa aagtattcct
    16981 tgtattgtta aagaaaatct aacggataaa gaagcctata cctatgtaat tgaaacaaac
    17041 cttatacagc gttctttctc cgatttactg ccgacggaaa aagcccttgt tcttaaaatg
    17101 agatatgaaa aaatagcaag tcagggcaag agaaatgatt tgcaaaagga gataaacaat
    17161 ttagatcagg gaattataga aaaggaaagt aaagaggaag ataaaataga cagcagaaaa
    17221 acacttggaa aagaatataa tctttcaggg gcatctattg caaggtacct aagattaaat
    17281 gaattatcta agtcttggaa aaaagatgtg gatgaagata aaataggttt gacgatggca
    17341 gtagatttat cctatctttc caaagaaata caggaatatc tgtatcagaa gtgcgaagaa
    17401 ttggaactaa gtttaaaacc aagcgatgcc aaagcactcc atctgatgaa cagacaagaa
    17461 gatctgaatc aagagatggt tataacatac ttgctgaact tgaaaaaaac gaaggtaaaa
    17521 aagtatcaga atatcaaact atctcagagt gtctataaaa agttttttca tgatgaaagg
    17581 aaagaagatg tagaagaaat tatagaaaaa gcattggaaa tttactttaa ggaatatatt
    17641 ggtcagtgaa aagacaaaat tataaattta aggtataata taaggtatta aaaagggaaa
    17701 agacctgttt aacaggataa gatataaaag aggcaggtgt cagaatggac gaaataaaat
    17761 tgtatgaaaa taaagagata cgctccattt gggacgaaga aaaagaagag tggtattttt
    17821 cagtagtcga tgtagttgga gttttgacag aacaagaaaa cgtaagaggt gctagtacct
    17881 attgggctgt actaaaaaag agattaaaag aagaaggaaa tgaactgctt acaatttgta
    17941 agcagttgaa aatgaaagca acagatggaa aaatgcgttt aactgatgta gcagatatgc
    18001 aaggaatatt ccgtattatc cagtccatcc catcccctaa agcagaacct tttaagttat
    18061 ggcttgctga ggttggaaaa gaacgaattg atgaaattat cgatcctgaa cttacgattg
    18121 acagagcctt agaaacttat ctaaagaagg gatatacacg tgagtggata aatcaaagac
    18181 ttcaagccat tcaggtaaga aaagaactga ctgatgcttg ggatgaccat gggatacaaa
    18241 aaggcaaaga atacgcaatt cttactgatg aaatcaccaa agcatggtcc ggaatgacaa
    18301 caagaggtta taaaaatctg aagggtttga aaaaggaaaa tctaagggat aatatgacca
    18361 ctcttgaaat agttcttaat atgcttgcag aagccacaac aa
//
LOCUS       DARYXZ010000045        18169 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYXZ010000045 DARYXZ010000000
VERSION     DARYXZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18169
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            56..292
                     /locus_tag="TV186_001525"
     CDS             56..292
                     /locus_tag="TV186_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL1532905.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            356..1627
                     /gene="murA"
                     /locus_tag="TV186_001526"
     CDS             356..1627
                     /gene="murA"
                     /locus_tag="TV186_001526"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1532906.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1631..1819
                     /locus_tag="TV186_001527"
     CDS             1631..1819
                     /locus_tag="TV186_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1532907.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1851..2729
                     /locus_tag="TV186_001528"
     CDS             1851..2729
                     /locus_tag="TV186_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1532908.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2743..2901
                     /locus_tag="TV186_001529"
     CDS             2743..2901
                     /locus_tag="TV186_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532909.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3641..4684
                     /gene="pheS"
                     /locus_tag="TV186_001530"
     CDS             3641..4684
                     /gene="pheS"
                     /locus_tag="TV186_001530"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL1532910.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4874..7279
                     /locus_tag="TV186_001531"
     CDS             4874..7279
                     /locus_tag="TV186_001531"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL1532911.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVENVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7514..8590
                     /locus_tag="TV186_001532"
     CDS             7514..8590
                     /locus_tag="TV186_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1532912.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8600..9304
                     /locus_tag="TV186_001533"
     CDS             8600..9304
                     /locus_tag="TV186_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532913.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
     gene            9643..10767
                     /locus_tag="TV186_001534"
     CDS             9643..10767
                     /locus_tag="TV186_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL1532914.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(10929..11522)
                     /locus_tag="TV186_001535"
                     /pseudo
     CDS             complement(10929..11522)
                     /locus_tag="TV186_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622734.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            11591..13564
                     /locus_tag="TV186_001536"
     CDS             11591..13564
                     /locus_tag="TV186_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL1532915.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
     gene            13588..15030
                     /locus_tag="TV186_001537"
     CDS             13588..15030
                     /locus_tag="TV186_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL1532916.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            15111..15920
                     /locus_tag="TV186_001538"
     CDS             15111..15920
                     /locus_tag="TV186_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1532917.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            16232..17389
                     /locus_tag="TV186_001539"
     CDS             16232..17389
                     /locus_tag="TV186_001539"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678097.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1532918.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVV
                     EVWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHE
                     FRKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINR
                     FLSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL
                     LDAYINGYGYIHKFAKNTPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSE
                     ALYTGKAIGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERV
                     GLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            17475..>18169
                     /locus_tag="TV186_001540"
     CDS             17475..>18169
                     /locus_tag="TV186_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1532919.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
BASE COUNT         5631 a         3657 c         4096 g         4785 t
ORIGIN      
        1 ttcgtccaac tttttggggg cagtacattt gttagacttt tgatataata aagctatgga
       61 agtaattaga actcttttaa tgtttttcag ccatttatta tttattggca ttagttatca
      121 gctactcatt agcctagttg attggtcaaa attcattcat taccgaccag agaatatggg
      181 aaggcttcgc ttgcttgtcc tttttttggc aattgcctca ggctatttag ttagtcgctt
      241 tatgctggaa ttaattcaaa tcagtcagta tctgctgtat gatttccact agagtaggca
      301 gtcaggaagt atgatataat attagtacga tgaccagtag gaaatggaga agcttgtgga
      361 taaaataatc atagaaggtg ggagcacacg tttagaggga gaggtaacga tcgaaggcgc
      421 taaaaatgcc gttcttcctt tactagcagc tactatcctc ccctcaactg gaaagactgt
      481 cttgagaaat gtgccgattc tctcagatgt ttttacgatg aactatgttg tgcgtggcct
      541 aaatattgac gtcgactttg atgaggctgc caaccagatt acagttgatg cctcagggga
      601 cattttagat gttgccccgt acgagtatgt cagccaaatg cgcgcctcaa ttgtggtttt
      661 aggcccgatt ttagctcgta atggccatgc caaggtatcg atgcctggag gctgtacgat
      721 tggcagtagg ccgatcgatt tgcatttaaa gggcctagag gctatgggcg ctgagatcac
      781 ccagcagggt ggtgacatca ctgcaaaggc tgagcgccta aagggggcaa tgatctatat
      841 ggatttccca tcagtggggg ctacgcaaaa tttgatgatg gcagcgaccc ttgctgatgg
      901 tgtgacagtc attgagaatg ctgctcgcga gcctgagatt gttgacctag cccagctgct
      961 caacaaaatg ggggctaagg ttcgtggggc aggtaccgaa accctgacca taacgggtgt
     1021 caccagtcta tgtggggttg agcatgatgt tgttcaggat cgtatcgaag caggtacctt
     1081 tatgattgct gcagcaatga cctccggtaa tgtgctgatt agagatgctg tatgggagca
     1141 taatcggccc ttgatttcta agctcatgga aatgggagtg tctgttgtcg aagaggatgc
     1201 aggcattagg gtgcaggctg atgtgactaa actaaggcct gtcactgtta aaactcttcc
     1261 tcacccaggc tttccaacag atatgcaggc tcagtttaca gcccttatgg ccattgttaa
     1321 gggagaatct acgatggtgg aaacagtctt tgaaaatcgt ttccagcacc tagaagaaat
     1381 gcgacgcatg ggcttacaat ctgaggtatt gcgtgataca gctatgattc atggtggtca
     1441 cgaattacag ggagcgcctg tgatgtcaac agacctgcga gctagtgcag ccctcatctt
     1501 aacgggaatg gttgccaaag gcaggaccac tgtgaataaa ttgaaccatt tagatcgtgg
     1561 ctattatcag tttcatgaaa agcttgccaa gctaggtgcc aacattcagc gaattagtga
     1621 ggagtagtca atgactaatg gttggagata tgtcataaat cagctaatgc taatcatagc
     1681 tattggactg ctcggactct tttgtctggc gctgggacta atgattggct atagccttat
     1741 cggtgatggc caaaatcctt tagcgatttt atcgccagat aagtgggctg agctgattca
     1801 taaatttacg ggaaagtagg catggcctgc tttttatgat aagaggaaag atgatcaaaa
     1861 agaagaaaga catcaggctg cttaatgcct ttttagcgct cttgcttgtt cttggaacag
     1921 gttatttggc aggacatgat gacctagcag ctgataaccc gatcaagcag gtctaccaaa
     1981 ggattcttgg ctctgacacg cagcaagccg ggctaccaaa ggcaagccga gactgggaca
     2041 ctccctccaa ggccttggca gattcggtca tgacagccac catcaaacag caattaggtg
     2101 atgtgattac ttggaatggc actggtgcct atatcattaa ccataataaa acgacgctaa
     2161 atgcaaaggt agctagtctc ccctatgcca ataataaaac aaagatggta caagggcaaa
     2221 gcgttcctac cgtagccaat gccctgctaa ccaagtcaac ccgacaatat cagaagcgca
     2281 atgacactgg aaatggctat agctcatgga agcctgctgg ctggcatcag gttcaggggt
     2341 taaagggaag gtatagtcac gcagtggata gagggcatct tctaggctat gcgcttgttg
     2401 gcgggctaaa aggctttgat gcctcaatgg ctaatcctag taatatcgct actcaaaccg
     2461 catgggctaa ccaagcagct aacgagagat caaccggaca aaactattat gaaacaaaaa
     2521 ttcgcaaagc cctagatagc aataagcgtg tccgctatcg tgtaactttg ctttatgagg
     2581 gaaataatct cttagcaagc ggcagtcatc ttgaggcaaa gtcatcagat ggtagcttag
     2641 aatttaacgt ctttatccct aatgtacagg ctggattaca gattgattat caaacaggtc
     2701 agatcactgt agcttcttcc cagccttagt gaggcacatc acatggcaaa agctgatcac
     2761 gtagctagcc atcatggcag agaagcatta gtccttgtag tccctcaaag aaaggtgcta
     2821 acaatatttg gtcttgtggc tttagtagaa aaacagatag gtcctttagt cgaagcacca
     2881 agcatgccag ctcctgatta ggacaaatgt caaggctaag cggtggtaag ttaaagtctc
     2941 acaaaagaca agactggact tttggctata gtcctttatg actgatgcca gctgataatg
     3001 gctcaagatg attgaggttt ctagcaatgc ttgtggctag cctatcgtct tagttagcgc
     3061 tgattgatga gatgttgaac agttcttgac taaaagcatc cctaccctta cgcctacgtc
     3121 ctggttagtg aagaaataag cattgtcata aaggcatttt tttgatacaa taaaagtaat
     3181 tgaatagcag tctatgagac tagtactaat agggaagtta atagggaatg ggggtcgtga
     3241 ctggaagcct tcttaatgaa acgattagga attcactcaa tcaaggacga ggtaattaag
     3301 gtctgacttg ctcagatgaa aacggatggt accgcgtgtc aacgctccgc tttagatagg
     3361 agccttgata cgcctttttt gatgacgtgc tgttactatt agctatttaa tcacaagcaa
     3421 gcactagcca gccaaaagta agtgatcact ataagcatag aaagatagga gctgtagctt
     3481 atctagaaaa gcaagggtga tcagtcgtcc gcccaaaagt ctttcttagc ttttgtgatg
     3541 tgactagctg acctagctgc tcacagctta gcctaaaagg cctattagca caaggactgc
     3601 cagcattaat gcaatcattt tccaaacaga agggaatatc atggatttac aagcacaatt
     3661 agaagaactg aaaaccaaga cacaagaagc gctcaagcag ctaaatggtg accacagcaa
     3721 ggaattacag gagctgcggg ttgctgtcct tgggaaaaaa ggaacgctta ccgaactgct
     3781 caagggacta aaggatctct caaatgacct gcgtcctgtt gttggcaaac aggtcaatga
     3841 gcttcgtgac tttttgaccc aagcctttga agagcaggct aaggtggttg aggcagcaaa
     3901 gattcaggcc aagctagatt ctgaaagcat tgatgtgact ttgccaggcc gtcagatgaa
     3961 gcagggctat cgacatgtgc tcactcaaat cagtgaagaa attgaggaca ttttcttggg
     4021 catgggcttt caaattgttg atggctttga ggttgaaaag gattattata attttgaacg
     4081 catgaacctt ccaaaggatc atccggctcg tgatatgcaa gacaccttct atatcacaga
     4141 ggatattttg ctgcgcaccc acaccagtcc tgtacaggca cgaacactgg accagcatga
     4201 tttttcaaag gggcctctca agatgatttc acctggacgt gttttccgtc gtgacaccga
     4261 tgatgccact cattctcatc aatttcacca aattgaaggc ttagtcgttg gtaagtctat
     4321 ttctatggga gacttgaagg ggactcttga gatgatcatt aaaaagatgt ttggtaagga
     4381 gcgtaagatt cgcctgcgcc catcctattt cccttttact gagccatctg ttgaggttga
     4441 tgtctcatgc ttcaaatgtg gtggtaaagg ctgcaatgtc tgcaaaaaaa caggctggat
     4501 tgaaattctt ggagctggta tggtgcaccc aagcgtttta gaaatgtcag gtgtgaatgc
     4561 gcaggagtat tcaggctttg cctttgggct tggtcaagag cgcatcgcca tgctgcgcta
     4621 tggtatcaac gatattcgag gcttctacca aggagatagt cgcttttcta agcagtttaa
     4681 gtaatagtga tcatatggtc aaaaaccaaa tcatcagttt gaaaaaagaa ctgacgctca
     4741 atctggagct gttctttgga ttagaatcag aaaggaaaaa gacgggtaaa gagcaaagaa
     4801 gtgattggct agcttatctc aagcaggtgc taggcagatc tctcatcagc gctcactact
     4861 ctattgaagg cttatgttag tatcttataa atggttgaaa aaattagttg acattgatgt
     4921 ctcaccggcc gagctagctg aaaaaatgtc aacaacaggt atcgaagtag aaggcatcac
     4981 cagcccctct gaaggtttat caaagctagt tgttgggcat attgtctcat gtgacgctgt
     5041 tccagaaacg cacctgcacc tttgtcaggt caacacagga gatgatgagc ttcgtcaaat
     5101 tgtctgcggt gcacctaatg tcaaagcagg gattaatgtg attgttgcgc tgcctggagc
     5161 tcgtattgca gacaattaca agattaaaaa gggtaaaata cgcggtatgg agtctcttgg
     5221 catgatctgc tcacttcagg agcttggctt accagatgcg attattccaa aagatttttc
     5281 agaaggtatc cagatcctac cggaaacagc agcagcaggt gatagcattt tcccttacct
     5341 tgatttagat gacaatatca ttgagctttc catcacacct aatcgtgctg atgccttatc
     5401 aatgcgtggt gttgcccatg aggtggcagc tatctatggc aagtcagtgt catttccaga
     5461 aaagcccctt atcgaatccg ctaaagcagc agctgatagt ctagaggttg ctattgactc
     5521 tgacaaggtg ctgacctatg ctagtcgtat tgttgaaaat gtcaccgtca agccaagtcc
     5581 gcaatggctg caaaatcttc tgatgaacgc tggcattcgt ccaatcaaca atgttgttga
     5641 tgtgaccaat tatgtcttgc tgtattttgg tcagccaatg catgcctttg attatgatac
     5701 ctttgctgat cataagcttt tagcgcgtga tgcgcgtgag ggagaaaggc ttgtcaccct
     5761 tgatggagaa gagcgtgtgc taaccacaga tgacattgtt attaccgtag cagaccagcc
     5821 agtggctcta gctggtatta tgggaggcaa atcaacagaa atcaccgcct cctcaaagac
     5881 agtggtgctt gaagcagcag tctttaatgg caaatcaatc cgtaaaacaa gcagtcggct
     5941 aagtcttcgt tcagaaagct catcacgctt tgaaaaaggg attaaccatg acacgcttgt
     6001 agaggcctta gattttgcgg cagccatgct agaagagcta gccggtggga ctgttttagc
     6061 agggcgcttg caggcaggct cactgcctac caatccggta gaggtttcaa ccagccttga
     6121 ttacgtcaat gtccgcttgg gaacagcctt gagctttact gatattgagg ggatttttgc
     6181 aaggcttggc tttggtatta gcggaactgc tgaacacttt accgtttcag tgccacgacg
     6241 ccggtgggat ataacaattc cggctgacct agtcgaagaa attgcccgta tctatggcta
     6301 tgatcgattg ccaaccacat taccagaagc tgctggcaca gccgcagaat taaccaaaac
     6361 acaggccctt cgtcgtcagc tgcgtggtct tgcagaggga ctgggtttaa cagaaatcat
     6421 ttcctatgct ctaacaacac ctgaaaaggc ccttgaattt gcaatgaagc caagccagtt
     6481 aacagagctg atgtggccaa tgtcagtcga gcgctctgtc cttcgtcaaa gcatggtatc
     6541 aggtatgctt gacacccttg cctacaatgt ggcacgtcaa cagcataacc ttgccgttta
     6601 tgagattggt aaggtctttg agcaagaggg caatcccaag gagacattac caacagagct
     6661 taatcacttt gcctttgcta tcacaggctt agtagcagac aaggattttc agacacaagc
     6721 gcaagcggtt gatttttacc atactaaggg aatcctagag tgtctctttg ataagctagg
     6781 actgtctgtg gattatatcc caacaaagga gatggcgagc atgcacccag gacgtaccgc
     6841 acgtattcag ctaggagatc aagtgattgg ctttgttggt caggtgcacc cacaggctgc
     6901 taaggcttat catatcccag agacctatgt tgcagagctt gacctgactg ctatagaggc
     6961 agctctacca gctcatcatg cctttgtgga aatcaccaaa tacccagcta tggtaaggga
     7021 tattgcctta ttggttgatg cctcaaccag tcatcaagcc attctttcag cgatcacgtc
     7081 tgccaaggta aagcgtctaa cagagattaa gctctttgac atttacgcag gagcaattat
     7141 tgcggccggt aaaaaatcaa tggcctatag cctgaccttc caaaatccaa cagacaatct
     7201 gactgatgag gaggttgccg gctacatgga gaaaatcacc aaggccttgg tagaaaaggt
     7261 tggtgcagag gtgagataag gacgcttcta atgactagct acctaaaaaa agctcatttc
     7321 aaaggcttag ctgcaattgt tctgttgcgg ctgagctttt tttgatgctt agactgtcct
     7381 tatcctatgc tagttgcagc aagggtttag agatgatttt atttaaatta tcagtcaaaa
     7441 atattttttc taatcaaatt cctagcttta tctgatctcc tctgctatac tgtgcaataa
     7501 gtaaggagat tatatgtttt tagccctaaa tgaaataaaa caagctaagc tcagatatgg
     7561 cttgattatg ggactgctct gtttagtagc ctatttgatg ttctttttat ccggtttagc
     7621 ctttggatta atgcaggaaa atcgctcggc agttgacagc tggcaggcag atacagttct
     7681 tttgtcaaag gacgctgacg ccaatctcag cctatcctct ttaaagacca gtcagcttaa
     7741 ggagatcaag gctgatgagg tcactcccct agcccagctg aatacagttg cttggtcaac
     7801 ccaagctcca acagaagaag acaaagaaaa aatcagcttt tttggcattg agagagagtc
     7861 ctttctcaag cctacaatca caaaaggaag gctatttaag tcagacaaag aggtggtgat
     7921 tgatcaaagc cttgctgaga aaggaggctt taagcttgga gatcagctgc gggtatcggc
     7981 ctctaaccag acctatacca tcgttggcta taccaagaat gctagcttta acgtgtcacc
     8041 tgttgcttac ctcaacctga cagcctttca gggcttactg tatggtcaag aagcaggcgc
     8101 acaagaccca aatgttaatg cctttattat caaaggcaag ctagctgact atcccaagga
     8161 agagcttcag cagctaacga ttggcgactt catcaacaag ctgccgggct atagtgcaca
     8221 gctcttgacc tttggcttta tgattgggtt tttagtgtta atctcagcca ttatcattgg
     8281 tatttttatg tatgtgctga ccattcaaaa ggcaccaatc tttggtatca tgaaggcaca
     8341 aggcattgct aatcgtacca ttgcaaatgc tgtgctatca caaacctttg tcctaagcct
     8401 tttgggcagc agccttggcc tactaggcac ctggctaagc tcgcttgtct taccagcaac
     8461 agttcccttt cagagcaatt ggtacctata tgcgcttatt ttagttgcta tggtagtctt
     8521 tgcagtatta ggcaccctct tttcagtctt tacgattgtt agaattgacc ctctagaggc
     8581 cattggttag gagaagaata tgacagtatt agcatttaag caggtcacaa agtcctttaa
     8641 ggacggtgat cagaccattg aagccctgaa aaagacggat tttgcgatta aagcaggcga
     8701 gtttgtcgcc cttataggtc catcaggctc aggcaaatca acctttctga ccattgcagg
     8761 tggtctacaa acaccaagct caggacaatt tttagtcaat ggcaaggatt acaccaacct
     8821 atctgaaaag gaacgatcaa aactacgctt taaggacatt ggctttatcc tgcaggcttc
     8881 taatttgatt ccatttttaa ccgtcaaaca gcagctagaa ttagttgaca agttgaccaa
     8941 gcacaagcag gaagcaaagc gtcagcagct ctttgaggac ttgggaatcg ctaagctggc
     9001 taataagctg ccccaagatt tatccggtgg cgagcgtcag cgtgttgcca ttgccagagc
     9061 cctataccat gatcctgtga tcattttagc agatgagccg actgccagtc tggatactga
     9121 aaaggccttt gaggtcgttg aacttctagc taaagaaagc aaggaaaaaa acaaggcaat
     9181 tatcatggta acccatgata accgtatgat tgactattgc gataaggtct atcgcatgca
     9241 ggacggccaa ttgagtcaag acaatcatca tatagctagc aatgccgcaa tgactcaaaa
     9301 ctaatcgaat aggaaaagct ctgctctagc gatatagcag ggctttttag ctgctctaaa
     9361 ttatctcaaa agttcctttt actgatattt aatattttct gtatttttaa tttatagaaa
     9421 aataaagaaa catgctgaga gttgatcaaa acacttacta tacttacgat gacaagtaac
     9481 ttgctaaagt aatggttgac atataattgt aaaaaaacag aaataaaaaa aaaacggttt
     9541 aatattgacc taattggcaa taacgtttac aataaaggta taattatctg ccgttgataa
     9601 ttaggagaca tcatgtctag ataaaaacaa aaggggaata aaatggcaaa aaaagaaatg
     9661 aagttttacc ttcgtaaatc agcctttggg ctagcttcag tatcagcagc cctcttggtt
     9721 ggtgcggcag ctgtatcagc agattctgtt gagtcagctg ggcctgtagc agttgctgtt
     9781 acagatagtt tagatagtga agccgcagct acaaaggcag aagctgatct agttgctgca
     9841 aaagcagacc tagcagcagc agaagtagca atcacagctg caaaagctga atttgacacc
     9901 gctcaagcag acctagctac cgctgaagct actatcgcag agcttgagca aaaaattcct
     9961 gagttagaga aaaaaattca agaagctcag gaaaaactaa actatgaaaa tcgaccatca
    10021 cctaaacgtg tgggcagtga tgatgaagat gacacagtag ctagaaagct tatgtcagaa
    10081 aaggaagctc ttaaggctga gcttcaaaag actaaagaag cgctagatac agctaaaaga
    10141 gcttatgctg gcatcgaaga aagaaaacaa gtagcagcaa ctaagctaga tgcagctaac
    10201 aaggcttttg ctggagttga agaaaagcat gctcaagcaa tggctgcatt tggagcagca
    10261 ttcgcagcat acaaggaagc tgttaaggct gaattgaagg cagcaggtgc tagcgacttc
    10321 tacaccaaga agattgactc tgccgacaca gttgacggtg ttaagacact cagagaaatg
    10381 atcttagact caattgctaa gccagaggtt gaaccagagg ctaagcctga acctaagcca
    10441 gaaccaaaac ctgagccaaa acctgagcca aaaccagaac ctaagccaga accaaaacct
    10501 gagcctaagc cagagccaaa accagaacct aagcctgagc ctaagccaga accaaaacca
    10561 gaacctaagc caaaacctca acctaaacca gctccagctc caaaacctga agctaagaag
    10621 gaagagaaga aagcagcgcc taagcaagac accaacaaat tgccatcaac aggtgaagct
    10681 acaaatccat tcttcaccgc ggcagctctt gcagttatgg caggtgcagg cgtggctgca
    10741 gtgtcaacaa gacgcaaaga aaactaagcc ttatacccca gtggtaaagc ttgagcgaga
    10801 acaatttgtt ctcgcttttt tagtgtctta aaagcaccta cagcaatcat aggtgcttaa
    10861 caagatatgt ctaacgattg ctatcagctg tagagaataa aaaggagaga ctaagccttg
    10921 ctcacaagct acttagaccg aaggagcttt aggatttcta tgatttgctg aggggagtcc
    10981 ttacagccgc agctgatcca cttaatgatg atgacctcaa tagaggcaat gtatagctca
    11041 aaaacatatt tttgggtaac ttcaggataa tcttgtgatt ctgcacaatt catgaggttg
    11101 gaataggaaa taatatccct aatataatga ttaaaaattt tataaatatt aggataataa
    11161 aggattaagc tttgcatgac ctcctgattg tcagagaggt agtttaggat ttttaaggta
    11221 atagttgtat caagtgatgg ggattggtaa atgatagagg tgatatcatc taggtaaacg
    11281 ccgatcattt ccctatctaa gtccttctta gagttgaaat aatgttaaaa ggttgttcga
    11341 ctgatattag aagccttgct aatatctgat acagtaatac tgtccttatc cttgtattgt
    11401 agtagtcggc agtagctttt aattattttt ttacaagttt gtttattttt atccattgta
    11461 tcattaactc cttaaaattg aacattaatg ttaattttgt acataatatt ttttgctaac
    11521 attatacaat gatgaacgtg atttgtaaaa ttaaattttg caaatcaata atgtaaaagg
    11581 aggattttgt ttgaaacaac tgacaaagat cgttagtgtg gtcttgttgc tggtctttac
    11641 ccttagtgct agcctgcaca aggttcgggc aactaatctt agtgacaaca tcacatcatt
    11701 gacggttgct tcttcatcac tccgagatgg agagagaacg acggtaaagg ttgcgtttga
    11761 tgacaaaaaa cagaaaatca aggcagggga tacgatagag gtcacctggc ctacaagtgg
    11821 taatgtctac attcagggct ttaataaaac cataccgctt aatattagag gggtagatgt
    11881 tggtaccttg gaggtcacgc tagacaaggc tgttttcaca ttcaatcaaa atattgaaac
    11941 aatgcatgat gtctctggtt ggggagagtt tgatattact gttagaaatg tgacacaaac
    12001 caccgctgaa acatcaggaa cgaccacagt aaaggtaggc aatcgcactg ctactatcac
    12061 tgttactaag cctgaggcag gcactggtac cagctcattt tattataaga ctggtgatat
    12121 gcagcccaat gatactgagc gtgtgagatg gttcctgctg attaacaaca acaaggaatg
    12181 ggtggccaat actgttacag tcgaagacga tattcaaggt ggtcaaacct tggatatgag
    12241 cagctttgac atcaccgtat ctggttatcg taacgagcgc ttcgttgggg aaaacgctct
    12301 gacagagttt catacaacat ttccaaattc tgtcattacg gcaacagata atcacattag
    12361 tgtgcggtta gatcaatatg atgcctcaca aaacactgtc aacattgctt ataagacaaa
    12421 gataacggac tttgaccaaa aagaatttgc caacaacagt aaaatctggt accagatttt
    12481 atacaaggat caggtatcgg gtcaagagtc aaaccaccaa gtagccaata tcaatgctaa
    12541 cggcggggtt gatggcagtc gctataccag ctttactgtc aagaaaattt ggaatgacaa
    12601 ggaaaatcaa gacggtaagc gtccaaagac tattactgtt cagctttacg ccaatgatca
    12661 gaaagttaat gataagacca ttgaattgag tgatactaat agctggcaag caagttttgg
    12721 taagctggat aagtatgaca gtcagaacca aaaaattacc tacagtgtca aggaagtgat
    12781 ggttcctgtt ggctaccaat cgcaggttga gggggatagt ggagtaggat ttaccattac
    12841 caacacctat acaccagagg tcattagcat taccggtcaa aaaacttggg acgacaggga
    12901 aaaccaagac ggtaaacgtc ctaaggagat tacggttcgt ttattggcaa atgacgctgc
    12961 aactgacaag gtagcaactg cttcagagca aaccggctgg aagtatacat ttaccaatct
    13021 accgaaatac aaagatggta aacagatcac ctacacgatc caagaggacc ctgtggcaga
    13081 ttacaccaca accattcagg gatttgatat taccaatcat catgaggtag ccttgaccag
    13141 cctaaaggtc atcaaggttt ggaatgataa ggacgattat taccataaac gtcccaagga
    13201 gattaccatt ttgctaaagg cagatggcaa ggtgattcgt gaacatcaga tgacaccgga
    13261 tcagcaagga aaatgggaat acacctttga ccagctgccg gtctatcagg caggcaagaa
    13321 aatcagctac agcattgagg aaaaacaggt tgctggctat caagcccctg tctatgaggt
    13381 tgatgaaggc ttgaagcagg tcactgtaac caacaccctt aacccaagct acaagctgcc
    13441 tgacaccgga ggacaaggag tgaaatggta cctgttaatc ggtggcggtt ttatcatcgt
    13501 cgcaatcctt gtactgatca gcctttatca aaaacacaag cgccataaca tgtcaaaacc
    13561 ataacatgta atagaggaga gagagctatg aaaacaatca aattaatctt gacgagcttg
    13621 cttgtcacct tcctaacaat gctgtcagga aaggcatttg ctgatacagc aagctatacc
    13681 atcactgttg agggagctac agcaggtcac acctatgagg cttatcagat tttcaagggt
    13741 gacttgtttg acagtaccct atcaaacatc acatggggag gtggtgttac accttttgaa
    13801 tttgatggtt caaaagacgc tgctaagatt gcagagggat tgaaggaagc aaatgcagct
    13861 gcctttgcca aggaagcagg taagcacttg acagcaacca ttgcaggaac aggaacacat
    13921 gcaatcaccg ttaacgaggc tggctactac ctcatcaagg acaaaaatga ttctcaaaca
    13981 ggcaagcatg acgcctacac ctcatttgtc ctgaaggttg ttaaaaatac cagcttcaaa
    14041 ccaaaatctg ctatcccaac agtccttaaa aaggtcaagg accgtaatga caagacaggt
    14101 cttgagacag gctggcaaga ttcagctgac tatgacaaaa atgacaaggt gccattccag
    14161 ctaaccgcaa ccctaccgtc aaattacgat gcctttcaag aatactacct tgaatttgta
    14221 gataccttat caaaagggct aagctacaac aaagacgcca aggtctatgt ggttaatgga
    14281 gatactcgtc aagatattac taattcattt acagttagtg aagatggttc atcttttaaa
    14341 atcaataacc taaaggctgt tcagggagta acaataacag ctaccagtaa gatcgttgtc
    14401 gaatacactg ctaccctcaa tgaccaagcg gccatcggca aaaaaggaaa tccaaacgaa
    14461 gttgctttga aatactcaaa cgatccaaac gctcttggaa aaggagagga gtctccaaaa
    14521 ggggagacac caaaagacaa ggttatcgtt ttcacctata aaactatcat caataaggtt
    14581 gatcaagatc aaaaagccct aaaaggtgca ggctttaccc tttataagct ggtcaaaggt
    14641 gataatggcg aggaaaaata tcaaatagtc caagaaatta aagcagggga tacaactagc
    14701 tttgagtttg ttggacttga cgctggtgat tacaagctca gcgaaacaac aacacctggc
    14761 ggttacaaca ctattgcaga tgtcatgttc agcattgtag cgcagcatga aaccgagtca
    14821 gacgatcctc agttgactag cctaaccgtt gacaaagcaa ctggcttcac tgctgataca
    14881 gaagctggta ccgtatccgc aactattgtt aataaaaaag ggtctatcct cccttcgaca
    14941 ggaagtatcg gaacaaccat gctctatgtg tttggagtaa tgctaatgac aatatcaacg
    15001 ctgtttatct ttcgtcagaa acagcaataa gatcgtgtga gtaggtaaaa agaagtggat
    15061 agacgtctta ccaagaccta ttcacctctt tttttgatag aggctataga atgaagaaaa
    15121 gtgtcatttt ttggagtgtg attttggtgg caggctgtct gattgtcctt taccccaccc
    15181 ttagtaacta ttggaatgca cagcaccaat cacagctcat cgctgactat gtctcaagca
    15241 cgcaagcttt gagacataag gatagtcagc tcatgctaga agcagccaat cagtacaatc
    15301 agcagctaaa agctaaccat gatcctgatt taaccttgac cgatagtgag gcagaagcct
    15361 atcagcagca gctggatctg acaaatacag gtatcatggc ctacatagat attccaaagg
    15421 tgcatgagcg gctgccgatt tatcatggca ccgatgagga gatcctacag gtggctatcg
    15481 gtcatcttgc aggcacctct ttgcctgtag gtggcaaggg aacacatgct gtcatctcag
    15541 gacatcgagg gttaccctct gccaagctat ttaccaatat tgataagctg aggattaacg
    15601 atacctttac catcaccagt cttaatagga ctatgaccta tcaggtggat aagattgcta
    15661 ccgttttgcc tgatgatgtc agcctcttaa ggatagagga ggggaaggat ctggtaacct
    15721 tggtcacctg taccccctac ggtgtcaaca cgcatcggct cttggtcaga gggcatcgta
    15781 tcaaaacagc gacaccaacc gctgcaagag gatctcaaaa gcctagtagg ctaatcctct
    15841 ggctcttgct aatcagtgca ttagggctat ctctcgtact aataggcact tggcgctggc
    15901 gtaggaggtc taaagcatga gcaggctttc cagaagcaac taagtcaaat catcaaccct
    15961 tgataggtta ctgaggacct atcaggggat tttttagtgc taaattgcga ctatgattaa
    16021 aaacacagaa atcgtttttt tttcttagtg accgaaaacg ctttaaaaga gcgagcattt
    16081 ggagccttca aaagtgacat ctgagcataa catgataaaa ttgacttata aaacctaata
    16141 aaatgataaa aggaggagag ttaacgacaa aatattagat atttatttaa tttgttgttt
    16201 ttgaaaacgt tttataataa gaaaggatag catgatgaaa aaacaatcat tcacacactc
    16261 acgtaaacct aaattcggta tgagaaaatt atctattggc cttgcctcat gtatgctagg
    16321 aatgatgttc ctaacaacag gacatgtttc tggtgaggta gttgaagttt ggcctaatgg
    16381 gcaaaatcct aatggtaaaa tagaaattct aagtcaaact gagcactctg agcatttaca
    16441 gaaattacgc gatattgaag atttccaagc tcaaaagcaa gctgatcatg ttcgttacac
    16501 taaatggtta gatggggtaa ctgttgatga gcatgaattc agaaaaatca aggaatatga
    16561 cacagaatat tatgtaacac ctcttttaag tggtaaaggt tactatgata tcaataaaga
    16621 tttcaatcaa gatagtgata aatgtgctgc cgctgtagcg gctaatatgt tccattattg
    16681 gtttgataga aatagagaca gtattaatcg tttcttaagt caaagtccag gtgaaaatgg
    16741 tgttattaaa cttgaaaatg aaaaaacaat agaagtatca aaatttttag aaacttaccg
    16801 tagtgatggt gattatcttg ataaaagtcc gttttttgac cttatcagta acagctttaa
    16861 aggtcctgtt tgggcaaata agctattgga tgcttacatt aacggctatg gttatatcca
    16921 taaatttgct aaaaatactc cacattctaa aaataataat agtaaattta atttctttaa
    16981 aaaagtattt gatggtaatc tcttgacaga tattcaccaa atttttgatt ataacacttt
    17041 ttcagataaa ttaagtgagg ctctctatac tggtaaagcc attggattgg cctacggacc
    17101 tggagacttg cgtcgttcac taggtcatat tatttctgtc tggggagctg atcttgacga
    17161 tcagaatcgc gtggtagcta tttatgtaac tgattctgat gataaaaagt taactatagg
    17221 aaatgagaga gttggtttga agcgatataa agtatctagc gatgatcaag gtcgtgctcg
    17281 tctgacgact cgtgataaag ataacacagg tggtgaaatt cgatctattg aaacattaga
    17341 tatgggtaca caagagtggg cagattactt caacaagaca gaaaaataac aataacccct
    17401 acacatatat gattactcca gataaagcac acagcaatag actcagccag taaggaaagg
    17461 acgataacaa aacgatgcta acaaaccaaa cggggtacag gcatagactt agtaagcaga
    17521 agctacctat cagcatggtt tcctgcttgc taggaatggg ggtgctaacc tctccaacat
    17581 taatctcagc tgatgatagt tctcctacta tcatcattaa atcgggtgca ggtatgacaa
    17641 ttgatcctca attaccgaaa actctccttt ctaaacccga agagaaacca gaggaaacac
    17701 ctaaacttcc agatgagcga cattatggtg atgatgtcag accggaagaa acaccaaagc
    17761 ttccagacga gagacattat ggtgacgata taaaaccgga agagatgcca aagctcccag
    17821 atgagcgaca ttatggtgat gacatcagga agccgaaacc ggaggatact ccaaagccac
    17881 ctaatgaaag cggtcaaggt aatgacttaa aagaagattt ggagcttaaa aagcaacgtc
    17941 gagagcttac agagcagctt cgtgctttaa aaactattga ggaagtttta gagttcctga
    18001 gaaaaccaat tcctggattt gtaacagatg aagattggaa tttcttagta tcatttgtag
    18061 aaaaaggccc agaaaataaa acttttgaag tagataaatt aaaattacta gaaatcttct
    18121 caacctcaca aggtcataga gtttggttag gttaccttat tctggaaga
//
LOCUS       DARYXZ010000046        18128 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYXZ010000046 DARYXZ010000000
VERSION     DARYXZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18128
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            71..1321
                     /locus_tag="TV186_001541"
     CDS             71..1321
                     /locus_tag="TV186_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL1532920.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1430..2311
                     /gene="truB"
                     /locus_tag="TV186_001542"
     CDS             1430..2311
                     /gene="truB"
                     /locus_tag="TV186_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL1532921.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2325..3257
                     /locus_tag="TV186_001543"
     CDS             2325..3257
                     /locus_tag="TV186_001543"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL1532922.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3300..3704
                     /locus_tag="TV186_001544"
     CDS             3300..3704
                     /locus_tag="TV186_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL1532923.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3706..3984
                     /locus_tag="TV186_001545"
     CDS             3706..3984
                     /locus_tag="TV186_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL1532924.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            3974..4750
                     /locus_tag="TV186_001546"
     CDS             3974..4750
                     /locus_tag="TV186_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL1532925.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4767..6074
                     /locus_tag="TV186_001547"
     CDS             4767..6074
                     /locus_tag="TV186_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL1532926.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6212..7078
                     /locus_tag="TV186_001548"
     CDS             6212..7078
                     /locus_tag="TV186_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL1532927.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7089..8024
                     /gene="pstC"
                     /locus_tag="TV186_001549"
     CDS             7089..8024
                     /gene="pstC"
                     /locus_tag="TV186_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1532928.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8014..8901
                     /gene="pstA"
                     /locus_tag="TV186_001550"
     CDS             8014..8901
                     /gene="pstA"
                     /locus_tag="TV186_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1532929.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            8918..9721
                     /gene="pstB"
                     /locus_tag="TV186_001551"
     CDS             8918..9721
                     /gene="pstB"
                     /locus_tag="TV186_001551"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1532930.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9735..10493
                     /gene="pstB"
                     /locus_tag="TV186_001552"
     CDS             9735..10493
                     /gene="pstB"
                     /locus_tag="TV186_001552"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1532931.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10564..11217
                     /gene="phoU"
                     /locus_tag="TV186_001553"
     CDS             10564..11217
                     /gene="phoU"
                     /locus_tag="TV186_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1532932.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            11451..13988
                     /locus_tag="TV186_001554"
     CDS             11451..13988
                     /locus_tag="TV186_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL1532933.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            14407..15081
                     /locus_tag="TV186_001555"
     CDS             14407..15081
                     /locus_tag="TV186_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1532934.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            15074..16384
                     /locus_tag="TV186_001556"
     CDS             15074..16384
                     /locus_tag="TV186_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1532935.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVSQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
     gene            16769..17188
                     /locus_tag="TV186_001557"
     CDS             16769..17188
                     /locus_tag="TV186_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532936.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            17185..>18128
                     /locus_tag="TV186_001558"
     CDS             17185..>18128
                     /locus_tag="TV186_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532937.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITAAHAKQPATVFN
                     APSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYFGDDELGISRWVDGKAGIG
                     RHSLAAYRFNSKGQVIDRKGRPAAAQAPALATLSSKLTEYRLLKKKYVASNGISSSEE
                     FYLDQFQARAVAQALEQTTQLAQEEIIARRKEAVAEAEA"
BASE COUNT         5426 a         3360 c         4073 g         5269 t
ORIGIN      
        1 tctggaaaaa tcattttcta ggcttttttt gctataatgg cagtgagata attgcaagaa
       61 tggagaaatc atgaaagaac taaaatgtcc tcattgccat accttattta cggtcaatga
      121 gtctgactat agtcagattt tagcacaggt acgaggtcaa gagtttgaca aggagttggc
      181 acagcgctta gaaagtgaga tgaagctgca agaagcaagg gccaataacc gcttccaaga
      241 ggtgcttact aaaaaggagc aggctattca aagcctgacc aaccgcttgg agcgtattga
      301 gcaggaacag gcctatttga ggcaacagga gctagcccaa aaggataaag agctcctaga
      361 gcttcacaat cagctagata agctagagct tgagcagcaa tcaaggctcc agtctgccct
      421 tacagttgtt gaaaaggaac gtgatcacct aaaaaatcag ctcgtgctgc aggaaaaaga
      481 aagcgaactt tctctagcct ctgtgcgcag tgattatgag gtgcagttaa aggctgtcaa
      541 tgagcaggtt gagttttaca agaattttaa agcgcagcag tcaactaaag ctattggaga
      601 gagcttagag ctgtatgccg aaaccgagtt taacaaggtt cgcagctatg cctttccaaa
      661 tgccagtttt accaaggaca atcaagtgtc tcatcgaggc tcaaagggtg attatattta
      721 ccgagagcta gacaataatg gtgttgaaat tctctcaatc atgtttgaaa tgaaaaatga
      781 ggttgacacg accaagacca agcataaaaa tagtgatttc tttaaggaat tagataagga
      841 tcgccgggaa aagaattgtg aatatgctgt tcttgttacc atgcttgaag cagacaatga
      901 ttattacaat gcaggaattg ttgatgtcag tcatgactat gacaaaatgt atgtggttcg
      961 gcctcagctc tttattcatc tcatcggatt gctgcgtaac gctgctctta atagcttaaa
     1021 atataagcaa gaactggcgc ttgtcaggga gcagcacatt gatattacac attttgagga
     1081 ggacctagag cattttaagc atgcttttgc taaaaactac cagtctgcaa gcaataactt
     1141 taaaaaagcc gttgatgaaa ttgataagtc catcaagcgt atggaggagg tcaagcgctt
     1201 tctaacaact agcgaaaatc agctgcgttt agccaataac aagctagatg atgtctctgt
     1261 caaaaaacta accagaaata atccaaccat gcgcgataag tttcaagcaa tcaagcccta
     1321 ggattatctc agtcaggctt attgatagag gctttgttgc ttgtcaaaag ccttgtgaaa
     1381 tggttataat agataggcta atgatcaaaa caataaacga aagtaacaca tgataaacgg
     1441 aataatcaat ttaaaaaaag aagcaggcat gacatcacat gacgctgttt ttaagcttag
     1501 aaagctatta caagaaaaaa agattgggca tggagggacg cttgatcctg acgtggtcgg
     1561 tgttttgcct atagcagtgg ggaaggcaac gcgagttatt gaatacatga cagaagcagg
     1621 taaaacctat gagggagagg ttactcttgg ctattcaacg acaacagagg atgctagtgg
     1681 agagattgtt gaccaaacag tagtgccctt gagtttgact gaagcgatgg ttgatgaggc
     1741 aatgacacaa tttattggtc aaatgactca gattccaccg atgtattctg cggttaaggt
     1801 taatgggcgc aagctttatg attatgcacg agctggtgaa gcagtcgagc gccctaaaag
     1861 acaggtaacg attgaccagt ttgagcggac aagtcccttg acctttgcag gtggtctttg
     1921 ccgatttagc tttagggtga gctgtagcaa ggggacttat attaggacct tggcggttga
     1981 tctaggaaga atgcttggct atgcaagtca tatgtcttgg ctggttcgga cagcttcttc
     2041 gggtttaagt ttggatcagt cctatacctt gtcagagatt gctgagctgc tggataaaaa
     2101 ggacatgagc tttttattgc ctattgaata tggtgttagt gatttagcca gagtagtcgt
     2161 taatgactgg gagctgagag agctttcctt tggtagaaaa atcgctctat catgtgagga
     2221 aaatctgtta gcggcttttt atcaggacag cttgatcgct attttagaaa agcaagaagg
     2281 gctttacaag ccaagaaagg tttttattta gagaagattg atatatggat atacaacaca
     2341 ttaaaagcta tcaggagatt gatgaatcag ctgataccgt tttagtctta ggctactttg
     2401 atggtctgca ccgaggtcac aaggctctat ttgataaggc aaaggaaata tcacgtcagg
     2461 aaagcctaaa aatagtcacc ttgaccttcc atgagtcccc tcagctggcc tttacacgct
     2521 tttctcctga ttttttacga cacattacct atccagaaaa aaggtatgaa aaatttgctg
     2581 agtatggtgt tgataagctt tatttgcttg attttaccac gtcattttca aaactatcct
     2641 ctgatgattt cattgaccac tatattgggc gtttaagggt aaggcatatc gttgtaggct
     2701 ttgattatca ctttgggtgt gatcacgcag atagtcatta cttagctaaa cggataaaag
     2761 gaaccgttta tagcatttca gaggtcaaag aagaccagat caaaatctca tcaacacgta
     2821 tcagaagtct gattacagca ggagatgtcg ctaaggctaa tcagctgctt ggctatgagc
     2881 tttcaacaag aggaatggtt gtgcatggtg atgcgcgtgg gcgaaccatt ggttttccga
     2941 ctgccaatct tgcacctatt gataggacct atctgccagc tgatggtgtt tacgtgacag
     3001 atgtgctggt tagaggaaag cgctatcggt ctatgacgag tatcggcaag aacattacct
     3061 ttggtggtaa agagctgcga ttagaggcaa atatttttga ttttaatgag gacatttatg
     3121 gagaaactct tgaaattatt tggctagata ggattcgtga gatgaataaa tttagtgatg
     3181 ttagcacctt tatcagccaa ctaaagcagg ataaagaagc tgccataaat tggaaaaaag
     3241 atagccaagg ctattaaatt tttgtataat aaggtaagca caattaacag aggaaaagta
     3301 tgattacctt atttctatca ccaagctgta ctagctgccg taaggccaga gcctggctca
     3361 ccaagcatga cgttgacttt caagagcata atattattac cagcccactt agtcgtgagg
     3421 agctgttagc gatcctatcc tttactgaaa atggaacaga ggatattatt tcaacacgat
     3481 caaaggtttt tcaaaaattg gatattgata ttgatgagct gtctatcatg gatttgattg
     3541 atttgatcgc aaagaaccct agccttcttc gtaggccaat cattatggat agtaagcgca
     3601 tgcaaattgg ctttaatgaa gatgagatta gggcattttt gccaagggat tatcgtaagc
     3661 aagagctgcg ccaagcaacc ataaaggcag aaatcgaggg ataacatgtc agatcattat
     3721 cattacccac ttgatgtaag ctggagcact gaagagataa catcagtgct tcatttttta
     3781 aatcaggtag agttagccta tgaggctaag gtaggagcag aggagctact caaaagctat
     3841 gctgcctaca aggagattgt aagaagcaaa tcacaggaaa agcagattga ccgcgaattc
     3901 caacaagcca gtggctattc aacctatcaa gctgtcaaaa aagccagaga aattgagaaa
     3961 ggattctttt cccttggaag ataaatacgc atttgctaaa acgatcatca aagaggctgg
     4021 ccttctgatt aaggatagaa tgaaagatag cttagccatt gaaatcaaga cgcagcatga
     4081 tgatttagtg accaatgtag atcaagagac gcaggatttc ttaattgcta aaatcaaaca
     4141 ggcctatcct agtgaccata tgattgctga ggagggcggt atctgtcatg ctattacaga
     4201 tggcaaggtt tgggtgctgg atcctattga tggtacggtg aattttattg tacagaaagc
     4261 caattttgcg atcatgatgg cttattatga gaatggcgtc ggaaaattta gtctcattta
     4321 tgatgtcatg gcagatcagc ttttttcagg tggaggagat tttgctgtta ctttaaatga
     4381 tcaagtccta gcatcttatc aggataagcc gcttgatcgt agcttaattg gctgcaatgc
     4441 aggtatgctt tcaaggaacg attacaacct gcaccagttg attgatcaaa ccctaggagt
     4501 gagggtttat ggcggtgcag gcatttgcat gactaaggtg ttaaggcagc agctaatggc
     4561 ttatttctct tatattcaac cttgggatta tgcagcggca gccattatgg gcgaaagcct
     4621 tggctatgtc ctgttgacct tggagggaaa gcagccagac tttcagtcta gacagaaggt
     4681 gatgtttgtt cccaagtcta aactagccac cattcaatct ctgctgaaaa caaacgagaa
     4741 tacccaataa gattaaaatg aaaagcatgc aattaccaaa cgattttatt gaaaaatacc
     4801 aacagctgct aggttcagaa gcaaaagctt tttttgagag ctttgatcag cctgccatca
     4861 gtgcctacag gataaatccc ttaaagcacc aatcggtctg ccttgatcct cctattcctg
     4921 atacaccatg gggttactac ggcagggtat caggaaagtc tcctaaccac gtgtcaggtg
     4981 tggtgtattc ccaagagcct gctgctcaaa tggttgctca ggtggcctca cctgccaagg
     5041 gaactagagt gttggatttg gcagcagcgc caggtggcaa gtcaactcag ttacttgcct
     5101 atctagagaa tacaggactt ttagtgagta atgagatttc gaccaaacgc agcaaggcct
     5161 tagttgaaaa tatagagcgc tttggtgcta gaaatgttat tgtgacaaat gagtcagctg
     5221 acagactggc tgctgttttt ccagaatatt ttgacactat tgtctttgac gggccttgct
     5281 ctggtgaggg catgtttcgc aaggatccaa atgctgttag ctattggcac aaggattacc
     5341 cagcagcatg tgctagcctg caaagatcca ttttagcaga ggcgatacct atgctaaagc
     5401 caggtggtca gctgatttat tcgacctgca cctggtcgcc tgaagaaaat gaagaggttg
     5461 ttcgctggct actagaaagt tatgattttc ttgagctgga gcatatccct aagatcaatg
     5521 gtatggcaga ggggatcggt atgccacagg cagctagaat gtaccctcat cgctttaaag
     5581 gagagggaca gtttgttgct aagttaaagg atactagatc aacgatttcc tcttcaagct
     5641 acaaatctcc aaggtctaac ctcactcaag agcagctgag gctgtggcag gattttgaaa
     5701 aaaatcattt gaacataacc ttgtctggcc tattacaggt ctttggtgat cgtttgtact
     5761 tgttaccaga tggcttaccc tgtcttcgat cgcttaaaat agcaagaaat ggtctggaat
     5821 taggcacttt taagaaaaaa cgctttgagc cttcctatgc tctgggcttg gcattaagac
     5881 ctgaagaggt cagcttatct gttgagatta acgaagagga ctttgtcaca tacgcctcag
     5941 gaaataccat taccttacca gaatcttatg ctacagattg gtatcagctg gtcattaacg
     6001 gaaatggtct gggctttgct aaaatagttg gtcgcaccct taaaaatagc ttccctaagg
     6061 gcttacgttt ttaaggaatg gcataccatt aaatttttat aaatttaaat aaaacttctt
     6121 ccaaagcatt gttagatatg ttaatataaa gaatatgctg aagcttaatt cttcgctata
     6181 aacctttatt tttatgaata ggaatagaat aatgaaatcg aaaaagaaat tctttttgtt
     6241 aagtctttta gccttgtcgg ctttcttttt gtcagcctgc tcaagctgga ttgataaggg
     6301 agaatccata acagcggtag gctcaacagc attacagccc ttagtagaag ccgcagctga
     6361 tgagtttgga agcaataacc tcggaaaatc tgttaatgtt caaggaggcg gctctggcac
     6421 tggcttatca caggtgcagt caggtgctgt tcaggtaggc aatagtgatg tctttgcaga
     6481 agaaaaggac gggattgatg ctgctaagct tgttgatcac caggttgccg tagcaggact
     6541 tgctgtcatt gccaatccta aggtcaaggt atctaatctc acaagcaagc agctacaaaa
     6601 gattttctca ggtgaatata ccaactggaa gcaggttggt ggacaggatc ttgctatttc
     6661 agtgattaat cgagcggcaa gctcaggctc acgtgctacc tttgatagtg tcatcatgaa
     6721 gggtgttact gctaagcaaa gtcaagagca ggattctaac ggtatggtta aatcaattgt
     6781 gtctcagaca ccgggggcca tttcttactt atcctttgcc tatgtggatt cgtctgtaaa
     6841 atcattacga ttgaatggct ttaaggccaa tgccaaaaat gtagcaacca atgattggcc
     6901 catctggtcc tatgagcata tgtataccaa aggcaagcca gacggcttaa ccaaggaatt
     6961 tttggattat gtgctatcag atgaggtcca aaaaaccatt gtgacacata tgggttatat
     7021 tgctatcact gatatgaagg tcgtcaaatc ctatgatgga aaagttacag ataaataatg
     7081 ggggaattat gaaaaatcag gaattagcta agcaattagc ctcaccatca aaaaattcac
     7141 gacttgaagc atttggtcgt acgattacct ttttttgcct cgccttaatt gtttttatcg
     7201 ttgcaatgat tttacttttt gtggctcaaa agggcttgtc tacctttttt gtaaacaagg
     7261 ttaatctttt tgatttccta tttggtacag agtggcagcc tagcgttaaa aatgctgccg
     7321 gtgttcctta tcttggagct cttccgatga ttgctggatc gtttttagtc acgattttat
     7381 cagccttggt ggcaacacca tttgccattg gggcagcagt atttatgact gaaatttcac
     7441 ccaagtacgg ggcaaaacta ttacagccag cagttgaatt gcttgtaggt atcccgtcag
     7501 ttgtttatgg ctttattggc ttgcaggttg ttgttccttt tattcgttct atttttggtg
     7561 gaacaggctt tggtatccta tcaggggtct gtgtcttgtt tgtcatgatt ttaccgacgg
     7621 ttacctttat gacaacagat agtctgcgcg ctgttcctcg tcattatcgt gaggcttcta
     7681 tggctatggg ggctacacgt tggcaaacca tttggcgagt ggttttaaat gcggctcgtc
     7741 ctggtatttt tactgctgtt atttttggta tggctagagc ctttggtgag gccttagcca
     7801 ttcaaatggt tgtgggaaat tcagcagtca tgccggcttc actaaccact ccagcggcta
     7861 cattgacctc tgtattgact atgggaattg gtaatacagt tatgggaact gttcaaaata
     7921 atgtgctatg gtcattagcc cttgtcttat tgctgatgag tctagctttt aattcccttg
     7981 tcaaattaat tacgaaagag agaaagagaa attatgaacg ctaaaaaggt tgataaagta
     8041 gcaactggta gcttgtatac tattgctgga attattgtag ctattttagc ttccctaatt
     8101 ctgtttattc ttgtgcgtgg cctacctcac atcagctggt cgtttttaac agggaaatca
     8161 tcgtcctatg aagctggtgg aggtattggg attcagcttt ataattcatt tttcttgctg
     8221 gtagtaacct tgattatttc cattccccta tcaacaggtg ctggcattta tttggccgaa
     8281 tacgctaaaa aaggacctgt gacaaatgtg attagaacct gtattgaaat cctatcctca
     8341 ttgccatctg ttgtggttgg attgtttggc taccttattt ttgttgtaca gtttgaatat
     8401 ggcttttcta ttatatcagg tgcccttgct ttgacggtat ttaatcttcc gcaaatgaca
     8461 agaaacgttg aggatagctt gctgcatgtg catcatactc aaagagaggc agggctagcc
     8521 cttgggcttt cacgctggga aacggttttt catgtggtta ttccagaggc cttgccaagt
     8581 attgtgacag gtattgtttt ggcttcaggt cgtatctttg gtgaagcagc tgctcttatc
     8641 tatactgcgg gtcagtctgc cccagcgctt gattggtcaa attggaaccc tttgagcgtg
     8701 acaagcccta tttcaatttt ccgtcaatct gaaaccctag ctgttcatat ttggaaggtc
     8761 aatagtgaag ggacaatccc tgatgcaaca cttgtttctg ctggtagtgc agcggtgttg
     8821 ttgattttta tccttatttt caatctatca gctcgcttta ttggcaagcg tattcatgct
     8881 aagatgacag cagcaaaata agacattgga gagattcatg acagaatata attggaacga
     8941 acgtcatatc attacatttc cagaagaaac gattgcccta gctactaagg atctgcatgt
     9001 ttattatggt agcaaggagg caatcaaggg gattgatatg caattcgaaa aaaataaaat
     9061 tacagcccta attggaccct caggctgtgg caagtcaacc tatctgcgca gcctcaatcg
     9121 catgaatgac accattgata ttgctagagt aacaggtgaa attttgtatc aaggcattga
     9181 tgtcaatcga aaggacatga atgtgtatga aatccgtaag cacctaggaa tggtctttca
     9241 aaggccaaat ccatttgcca agtctattta taaaaacatc acctttgctc atgaaagagc
     9301 aggagtgaga gataaaaggg ttttagatga gattgtcgaa acctccctca agcaggctgc
     9361 actatgggat caggtcaagg acgatcttca taaatcagcc tttacccttt caggaggtca
     9421 gcagcagcgc ttgtgtattg ctagggctat ttcggttaag ccggatatct tgttgatgga
     9481 cgaaccagct tcagcccttg atcctattgc aaccatgcag ctagaagaaa ccatgtttga
     9541 gttgaagaag gattacacca ttattatcgt tactcataac atgcagcagg ccgctagagc
     9601 aagtgattac actgctttct tctatttggg tgacttaatt gaatacgata aaacgcgtaa
     9661 cattttccaa aacgctacct gtcagtccac aaatgattac gtctcagggc actttggtta
     9721 gaaagaagga tatgatggca gaacctattt tacaaatcag agatctttct gtttactata
     9781 ataaaaagaa aaccttaaag gacgtgtcct tagattttta cccaaatgaa atcacagcac
     9841 tcattggccc ttcagggtct gggaaatcaa cacttttgcg ttccatcaat cgcatgaatg
     9901 acctgaatcc agaggtaacc attacggggt caatcgttta taatggacat aacatttaca
     9961 gtccaagaac agacactgtt gatttgcgaa aagaaattgg tatggtcttt cagcagccca
    10021 atccctttcc aatgtctatc tatgaaaacg ttgtctatgg cttgcgccta aagggcatta
    10081 gagataaggc tgttttagat cacgctgttg aatcctctct caaaggagcc tccatctgga
    10141 gtgaggtcaa ggataggctt catgattcag ctgttggact atcaggaggt caacagcagc
    10201 gtgtctgcat agcaagggtt ctggcaacca gccctaaaat cattttgtta gatgagccaa
    10261 catcggcttt agatcccatt tcagccggca aaatcgaaga gaccctgttc tcactaaaaa
    10321 aggattatac gatggttatc gttacccgct ccatgcagca ggcctcgcgc ttgtcagacc
    10381 ggacaggctt cttcttagag ggagaccttc ttgagtttgg tcctactaag gcaatgttta
    10441 tgaaccctaa gaggaaggaa acagaagatt atatttcggg taaatttggc taagggatct
    10501 tgtttgtagt ctaggtatcc gctctgttta ggataataaa tgaatcaata gaaagaaaaa
    10561 atgatgttaa gaactaaatt tgaagaagaa ttagacaagc tacacaatca gttttactct
    10621 atgggaacag aagtcttgtc tcaaatcaat aaaaccgttc gtgcctttgt cagtcatgac
    10681 cgcgaattgg ccaaagaggt gattgaggaa gacgatacca tcaatggatt tgaaacaaaa
    10741 ttagaaaaaa agtctcttga aattatcgcc ttacagcagc ctgtttcaaa cgatttgcga
    10801 acagttatta ctgttttgaa ggcctcaagt gatattgagc gtatgggaga tcacgctgcc
    10861 tctatcgcta aagcaaccat tcgcatgaaa ggagaagagc gtatcccgat tgttgaggag
    10921 catatcaact tgatggggaa ggcagtcaag cagatggttg aagaggcgct aaatgcttat
    10981 attaatgcag atgatgccaa ggcctatgaa attgctgctt cagacgaaat cattgataat
    11041 tatttccgcg aaatccaatc tctagctgtc gaagaaattc gcaagacacc agatgccgtc
    11101 tttgctggca aggaatactt ccaggttctc atgtatttag agcgtatcgg tgactatgct
    11161 cgtaatattt gtgaatggat tgtctattta aaaactggaa aaattattga attataagaa
    11221 agtatggtat aatgggggct gggtgaactt ctcagttcct cgttttatta tagcgattaa
    11281 aaggttttag aggctggagc ttcagctgag ctgactatca gctgtcaagc ttctagacaa
    11341 aatgaaagat aacaataagc tagtcgtcta agggactaga cggcaggatt gattatatta
    11401 agaatgtgac cttgtcccat cactaattta atgacatatt aaggagttgt atgaaaaaag
    11461 tagaacatct tattgaaaag tttattcctg aaaattataa tattttctta gacattaatc
    11521 gcagcacaaa aaccttcaca ggtaatgttg caatcaatgg tgaagcatta gataatcaag
    11581 tgtcatttca ccaaaaggac ttggcaatca atgccatttt acttgacaat gaagctgtta
    11641 gctatcatgt tgacgatgac aatgagcttg tgcgtgttga gctgccagag actggtatga
    11701 tgacgcttgt cattgaattt tcaggtaata ttactgacaa tatgactggt atttacccgt
    11761 cctattacac aaaagatggt gaaaaacagg aggttatttc aacgcagttt gaaagccatt
    11821 ttgcgcgtga ggcctttcca tgtattgacg agcctgaagc aaaggctacc tttgacttaa
    11881 gcttgacatt tgaccaagca gagggcgaga ttgctctatc aaatatgcct gaggtcaatg
    11941 ctgagcgccg caaggagacc ggtctttgga cctttgagac aactcctaga atgtcttctt
    12001 atctgctggc ctttgcctta ggagacttgc atggcaaaac aacaaaaagt aaaaacggga
    12061 caacagttgg tgtttatgca accaaggctc acccactgac ctcgctagat ttttcattgg
    12121 atattgctgt acgtgtcatt gatttttacg aagactactt tggggttcgc tatcctattc
    12181 cgcaatctct aaatattgct cttcctgatt tttcatctgg agcgatggaa aactggggct
    12241 tgattaccta tcgtgaaatt tacctgttgg ttgatggcaa ttcaacagcc cgcagcagac
    12301 aaaatgttgc tcttgttgtg gcacacgaga ttgcccatca atggtttggt aatcttgtaa
    12361 ccatgaaatg gtgggacgat ctttggctaa atgaaagctt tgccaatatg atggaatatg
    12421 tagccatcaa tgctattgag ccgtcatggc gtatttttga ggatttccaa acaacaggtg
    12481 tgccgctggc tcttaagcgt gatgcaacag acggtgttca atcagtccat gttgctgtta
    12541 atcacccaga tgagattaat accctgtttg atccagctat tgtctatgcc aaaggtagcc
    12601 gcttaatgca tatgcttcgt cgctggattg gcgataagga ttttgcggca ggtctgcgcc
    12661 tttactttga aaagcatcaa taccgtaata ctgtaggacg tgatttgtgg caggctcttt
    12721 cagaagcttc tggtaaagat gttgctgcgt ttatggacgc ttggctagag cagccaggct
    12781 atcctgtctt aacggccaga gttgacaatg atcagttgat tctcagccaa aagcagttct
    12841 ttattggtga ggcaagcgac caaaagagac tatggccaat tccactaaat gcgaactgga
    12901 aaggtcttcc tgacgtactg acagaggagt ccatcgttat ttcaggcttt agtcaattag
    12961 ccgcccaaaa taaaggaaca cttcgcttta atacagaaaa tacagcgcat tacattacag
    13021 attatcaggg acagctcttt catagcttag ttgatgattt gaagcatctt gacaacacct
    13081 ctgcccttca agtgattcaa gagcgccgct tgctggctga tagcggtctg atttcttatg
    13141 cagagctggt tgacttaatc gctcagctag atgacaaaaa atcctatatg gttgctgcag
    13201 ctgttcagca ggttattaga ggcttagagc agttcattga tgaaggaacc tcagcagagc
    13261 agtccttcaa tcgattgatt tcttctattt tccaagagga cttcaggcag cttggatttg
    13321 aaaagagggc aaatgaatct gatgaagatg aaatggttcg tcaaattgct ttacatcacc
    13381 tgttggttgg aggcaatcgt gatgtgatca agcaggccaa gactatcttt gaagcttatg
    13441 caaatcgtat cgaagccatt ccagcagcca ttcgccgctc ggtattggtg agtcagatca
    13501 agtattttga aatagctgac ttggttgatg cttattttga tgcttatgtt gcaaccaagg
    13561 acaacaatct tcgagctgat ttgagcgccg ccttagcaac aacagctaat ccatcaactc
    13621 ttaagcgcat tcagtacagc ttaaaggata aggatattat taagccacag gacttagcag
    13681 cttggtacag ctttttgctt gatcaggcct ctgcacaaga aagcatttgg cgttgggcta
    13741 gagaaaattg gaagtggatt aaggcttcac tgggtggtga tatgagcttt gacaagttta
    13801 ttatttaccc tgctaaccat tttaaaacag cagagcgttt agctgaatat aaggccttct
    13861 ttgagccaca gcttgatgat atggcgatta gtcgcaatat ttcgatgggg ataaatgaaa
    13921 tttcagctcg agttgccctc attgatagtg aaaaggaagc tatcgctaat gctttaagtc
    13981 agtactaatg atatcacaaa ggagctgggg accatcctca actcctttat tggtgtcaaa
    14041 gctactatct ttaagtaaca tttagatcaa agggtaattg ctgtagctta gtggcactgc
    14101 ctgtcagctt ttggcaaatg aggaggcttc aatcataagc agtggttaat cttagcgccg
    14161 taaattacta gttgatcaga gtcagagctt aggacggata ggtcatagag acaattcttt
    14221 gtctgtcagt tttataactt aagtaggtct ccagactaac tgtatgctta tgacctgtca
    14281 tgagcaatag tttagcaaag cttaagcttt ttgtgttatc gttagattag agaattcatt
    14341 tagtaaggta atccctaaag actacttgag cgaggctgtt agtctttaga gaattgaggt
    14401 atcataatga taaaactatt attagtagaa gacgatttaa gcttgtcaaa ttctatcttt
    14461 gattttttag atgactttgc tgatgtgacg caggtttttg atggtgacga aggactctat
    14521 gaggcagaaa gcggtattta tgatttgatt ctgttagatt tgatgctgcc tgaaaaggat
    14581 ggctttcaag tgttaaaagc cttacgtgaa aaagacatca aaattcccgt cttgatcatg
    14641 actgccaaag aaagcatcga tgacaaaggg catggctttg agcttggtgc tgatgactat
    14701 ttaaccaagc ccttttacct agaagaatta aaaatgcgga ttcaggcctt gcttaagcgc
    14761 gtaggaaagt ttaatgacaa gagccttaaa tttggcaacc tgactgtaga tactacccgt
    14821 aaagaggtac aggtcaatgg gcaggccata gagctattag gcaaggagct tgatttacta
    14881 atctatatcc ttcaaaatca aaatgttatt ttgccaaaat cacaaatttt tgatcgtatc
    14941 tggggctttg atagtgatac cactatctct gttgtagagg tctatgtctc taaaattcgt
    15001 aagaagctta aggggacaga ctttgttaat catcttcaaa ccttgagaag tgtaggatat
    15061 atcttaaaag ctaatgaata aactaaaaaa aggattattg tccgataatt atacgcattt
    15121 ttttcatttc tttgctattt ttacaggcat ttttgttgtc atgaccatca ttattttaca
    15181 aatcatgagg tttagtgtct attccacagt agacagcagt ctcatttcgg tcagtcaaaa
    15241 tgccagcaac tatgctaata ggaccatggc gagaatatct tccttttatt ttgatgcaga
    15301 aaataacctt attcaggctc ttcctgaact ggaagcgtca aaatcacttg gctcctccac
    15361 cactaatatg gatattattt tatttagtgc taatgggacg atattgaact cctttgacgc
    15421 tttctctaat taccaaagct ttcgtttaga caaaagccag ctcaataaca ttgtcaccac
    15481 acagctgatg aatttttatg ggcaaaagga gaaataccat accctaaccg ttaaggttca
    15541 cattaaaaac tatccagcag tggcttatat gatggcagtg gttaatgttc agcagctgga
    15601 tactgctaat gagcgctatg aacagattat tatcatggtt atgattgtct tttggttaat
    15661 ttcgattttg gccagtattt atttggctaa gtggagcaga aagccaatta tggagagcta
    15721 tgccaagcaa aaaatgtttg tagaaaatgc cagtcatgag cttaggactc ctttagcggt
    15781 gctgcaaaat cgtttggaat cgctgtttag aaagcctaac gaaaccattt tagacaatag
    15841 cgagcatatt gcgtcaagcc tagatgaggt tcgtaatatg agaatattaa caactaatct
    15901 gttaaattta gccagaagtg atgatgggat caagccgcag ctagttgatg ttgatgcagc
    15961 cttttttgat actgtttttg aaaattatca attagttgca gaagagtcag gcaagcagtt
    16021 tatctcagtt aatcagatca ataggccctt aaagacggat aaggctttgc tcaagcagct
    16081 gatgaccatt ttgtttgata atgcgatcaa atacactgat cataacggtg tggttgaggt
    16141 caaggttaga acgaccgata agcatttatt gatttctgtt attgataatg gcccagggat
    16201 caaggatgat gataagaaaa agatttttga tcgcttttac cgagtggata aggcaagggc
    16261 acgccaaaaa ggagggtttg gactcggatt ggccttagcg cagcagatcg ttacctcatt
    16321 aaaaggaacg attaccgtca gtgataataa gcctaccggc gccatctttg aagtaaaatt
    16381 atagcactga gttcttgcta gcccataatc agtatgaaaa taacagtcac tagatcaaga
    16441 agtctagtga ctttttttat tgtcttcttt ttgctgttga ccaagcagtt gacaagaaaa
    16501 ttccaataga tagtttaaag ccaataaaac cattattagg cttgcattac aggcaggtat
    16561 caaacaaaga tatagaaaaa tataccataa aaaatctcat aaaagtgtca aaatggtaaa
    16621 aaattgccaa caatatgtcg atattatacc attattatag tataatattt ataatcgtat
    16681 cataatatta aaatatctgg tgtctagctg tttttgtaaa agcaaaaaac ttgcaacacc
    16741 ttatgataaa gcataaagga atacaagcat gatagtctac ctaaagcaac acaaaaatta
    16801 ctggaaatta gtcagcatag ccgctttaat cattatttta ggaggaatac taacaatgaa
    16861 ttggcttaat ggcgaagagc taaaaaagaa aaagtacaga caagagcagg atagggtagt
    16921 gaaatacata ggagagcata tagagctatg taatggtcag cctataacaa aaattgagtt
    16981 tatagaattt cagttagaaa ctgcaaccac cggaacttgg tcaataacaa caattgttaa
    17041 tgagaaatat ctgattcatt tttcagaaga tagattaggt gaagaaatac ggacttccta
    17101 ttattctcca aaagaattta agcaatacag tgaaaagatg aggaataata tgactaatgt
    17161 tgaaacaatt tattacgagg agaaatgatg attgatagag attataaaaa tatttcagag
    17221 gatgtgtata aggttgattc tggtaaagaa agagatccga ttcaagaagg atatccggtt
    17281 gccaatggaa aataccgcgt tcttgaagcc gaagataacc ccgacaatgg tatgcaggct
    17341 atggctgttg tgccaataaa agatggcaaa gaggatagaa gtcatatcgt cattgcctat
    17401 gccgggacaa atagcagtga tatacgcgat attgacaccg atattcaatc cgttgttttt
    17461 ggagatgatc aatacctgtg tacccatgag gagcctgatt cttttaaagt ggtcaagagt
    17521 cagctaagta ctgctaaagc cttttccgac tacattagga caagctaccc taacgctgcc
    17581 atctcctaca ccggacactc tctgggaggc tatctggcac tcatcacagc tgcccatgcc
    17641 aagcagcctg ccactgtctt taatgcgcca agctctgtta ataacctctc caaggaggct
    17701 attgactttg ttaaagccaa caagggactc taccacagct accgcattaa caatgactac
    17761 attggaaatc tgggcactta ctttggagat gatgagctag ggatttcaag atgggttgac
    17821 ggtaaggcgg gaataggacg tcatagctta gccgcttatc gcttcaactc aaagggtcag
    17881 gtgattgacc gtaagggtcg tcctgccgct gctcaagcac ctgctcttgc taccctaagc
    17941 tcaaagctaa ccgaataccg cctgctaaag aaaaagtatg tagcctctaa cggtattagc
    18001 agctcagagg agttttacct tgatcagttt caggctcgag cagtcgcaca ggctttggag
    18061 cagaccactc agcttgccca agaggagatc attgctcgcc ggaaggaggc ggttgcagag
    18121 gcagaggc
//
LOCUS       DARYXZ010000047        18070 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYXZ010000047 DARYXZ010000000
VERSION     DARYXZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18070
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            182..409
                     /locus_tag="TV186_001559"
     CDS             182..409
                     /locus_tag="TV186_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532938.1"
                     /translation="MTKNDFLTGFVLILLAACIFAAGFVIGSDCSSEHYEQQMTGLRM
                     QLVNTQQQLKRASEDRARRTKRIADLTGNGG"
     gene            413..835
                     /locus_tag="TV186_001560"
     CDS             413..835
                     /locus_tag="TV186_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1532939.1"
                     /translation="MIDEIELDLQKPEIPQFVADYIDDMHKNARTLRYAFKYMESNIK
                     MHKWCVFERQETFVNAFLYGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFS
                     EIIDTDFYSREDVRLTESEIRKDFDWAWREGFAKEVTE"
     gene            1003..1233
                     /locus_tag="TV186_001561"
     CDS             1003..1233
                     /locus_tag="TV186_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532940.1"
                     /translation="MAYLREERETVIHYDELDDCWTFETNVRRHITKIEKRIELYEIL
                     SEEFDDRGRRIYICAKMKTGTVSPFAKPPRRK"
     gene            1610..2044
                     /locus_tag="TV186_001562"
     CDS             1610..2044
                     /locus_tag="TV186_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1532941.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVHSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLSPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGSLIVEQGVFS"
     gene            2582..2656
                     /locus_tag="TV186_001563"
     tRNA            2582..2656
                     /locus_tag="TV186_001563"
                     /product="tRNA-OTHER"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
     gene            2815..3306
                     /locus_tag="TV186_001564"
     CDS             2815..3306
                     /locus_tag="TV186_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1532942.1"
                     /translation="MAKLTIKQQKFIDEYIICGNATEAALKAGYSKKTAGQIGEQNLK
                     KLEIKSAINERLKQLESSKIASAIEILQVLTAVLRQDLTEEVVTLNPVTGEYVTMQKK
                     PSIAEVIKAAGELLKRYPIQEQIEKIKQENELLRLKIETVKGAKPDTHLMEKLLEVIE
                     DGG"
     gene            3341..4594
                     /locus_tag="TV186_001565"
     CDS             3341..4594
                     /locus_tag="TV186_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1532943.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGNCEIKHDERGDHLLVTTPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDM
                     EKNVLDTLIGEPVEMYFCADGGQSDATSMSCNIVTRVRDNGKISFRLNRTAHYYHSGA
                     DTGQVKAMSTYARELKAFIDWCVKKYQLRYSDVFIDPACKALREELHAIGILTTGAPN
                     NAHDVNSKAKGIEVGIERGQTLISDGDFYLVNHKEEKYDHYHFLKELGLYSRDDKGKP
                     IDANNHSMDEFRYSVNVFVGRYKMK"
     gene            4604..6103
                     /locus_tag="TV186_001566"
     CDS             4604..6103
                     /locus_tag="TV186_001566"
                     /inference="COORDINATES: protein motif:HMM:TIGR01542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1532944.1"
                     /translation="MFRNLWTKIKGVMQKMGLIKGLKDLNLHREIELSDKHYDSIQIW
                     KELYQGYHDKIHDYYEKSILDGRKKKKRLTLNMPKVVTSELATLIFNEKCEINIGSEN
                     ESLTKLITETLEKNNFTQEFQRFLEYSFALGGMAIKAYLKKDGTIGLNFVQADSFIPI
                     SWDNAGISEAVFVDTQHRGKYKYTHLEWHTWESELYVVAHELFRTDKSNDDVGIRVPI
                     TEIYPDLKSQVVIEKLSRPLFVYLKPNSANNIDLSSPLGISIYHNSFDTLRAIDIAYD
                     SFEREFRLGRKRILVPATAIRTVVDSEGNFHRYFDATDETYEAFHTGEDSKIQDIKDI
                     SVELRVDEHIAAINALLNLLSMQIGFSPGSFSFDGVSGVKTATEVISENSKTFRTKQS
                     HETMVEATLKNLVAIIVDFGDLYGLIEGESKYNVTVTFDDSIAQDRTQDAQYYIGLVA
                     AGLISKKKAMMKLFNLSEEDAELEIQTIHEESRTTNDMSIDLFGLDGDA"
     gene            6103..7713
                     /locus_tag="TV186_001567"
     CDS             6103..7713
                     /locus_tag="TV186_001567"
                     /inference="COORDINATES: protein motif:HMM:NF017919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532945.1"
                     /translation="MDYDTHIQLSFDLIELYSDVERELLTSIGRRFAKHYDEMVAGDI
                     MDWQIRQLLEVGELRKEHIEIMRKSARVSRERMIEMLTEAGYTSAGRYEDFFKEAYVK
                     GLIKLNPSAADNSMRLLRVLNTYINQAEDTLNLVNTTMLQSGQDTFLDTVNQVVAYVS
                     TGIKTPQVAMRDALKNAGQKGLTVFRAKNGAQWSTETYLNMITRTMNSNISNAMEDER
                     RHEYGVDYIEVSSHAGARPRCAPYQGRIYYDGVGDDPLEKYPHFSETSYGEAAGLFGV
                     NCGHHKYPYVPGMSKQTFFPYSKSENDKTYAESQVQRKLEREVKQLKRERAILTAAKD
                     KEGAKLASQRLENKWQELRQFTAQTGRTRRYDREKSLNTILSEDKKKAIVKDNLKIRD
                     EYRAIKKAIPEVAPKNLETYYDMRYNGGKIYEDLVRDYKDYIRWSKAEFPTKKSFEGH
                     IDSHLKEFPGLTGKQYQKKAADLLSRPITDNILGYDTDSRRVRYDLENNIFALGRVKQ
                     GTITTMLKPKEGVDYFDNDWKREFDNLK"
     gene            7679..7900
                     /locus_tag="TV186_001568"
     CDS             7679..7900
                     /locus_tag="TV186_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532946.1"
                     /translation="MTGKESLIILNDLEYVHCPVCGTLTEVYDICDTCKWQNTGETNI
                     DGGPNYITLEEARRRWANGEPLRNFFKDQ"
     gene            7952..8236
                     /locus_tag="TV186_001569"
     CDS             7952..8236
                     /locus_tag="TV186_001569"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532947.1"
                     /translation="MNKRIEKKRRTQMMLDRILRIVELMSQATDDNFAILEKRLEKAE
                     KRNEELMEIILVNVKEVNNRFDELEICQKIVEDDVAELKKAKKKGWFSRK"
     gene            8322..8561
                     /locus_tag="TV186_001570"
     CDS             8322..8561
                     /locus_tag="TV186_001570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532948.1"
                     /translation="MAVIIVQTRGGDIEVPTPLPAMQANKAIQSQLFDKELTFLCVDN
                     HAFAKTEVLHVLVETEEDEELPQSKHKEEETCYMD"
     gene            8546..9148
                     /locus_tag="TV186_001571"
     CDS             8546..9148
                     /locus_tag="TV186_001571"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532949.1"
                     /translation="MLHGLKHRLFKLAPDTGAGGGAEVTSETNAEAGRVEQTVSQQQA
                     DPVDTEAIKNQAINEVLSQLGVSSVEDAKANLASWNEYQEGQKTEFQKIQDSLTVANN
                     SLAERDTMIASLQAQLAAAQMGVPAENTSDVITLANSLVHDKTDINAAITTVLEKYPH
                     FKGGDADVADKPNFVTQTQSQTETTEDAFFKALGLTIKED"
     gene            9150..10022
                     /locus_tag="TV186_001572"
     CDS             9150..10022
                     /locus_tag="TV186_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532950.1"
                     /translation="MSINYITKHEGIFEKKLMQGALTSNLETPKVNWLGAKSFELPTI
                     SVTGYKAHTRSKGYNAGTVSNDKNTYTLGFDRDVEFFVDKADVDETNQELSMANISNT
                     FITEHATPEVDAYRFSKIATNAIDNSHFKQEDDYSTTNVYERLKAAILPIRKYGAGNI
                     IIYVSSEIMDFLERSKDFTRSIATTSPQGIDTRVTSLDGVQLIEVWDDARFKTKFDFT
                     TGFVKDGSGKDINFLIVAKPAVIAKAKFNSIYLFAPGQHTEGDGYLYQNRLYHDLFVL
                     KSKQDGVYVSHKSA"
     gene            10033..10281
                     /locus_tag="TV186_001573"
     CDS             10033..10281
                     /locus_tag="TV186_001573"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532951.1"
                     /translation="MKTYEKDNQVYKVQEGSELEIQLIADGFKEIIEANEKETDITKM
                     KLDKLKAYAENEGIIIPEDIKKKEDVLAFIKEQQQRGE"
     gene            10284..10670
                     /locus_tag="TV186_001574"
     CDS             10284..10670
                     /locus_tag="TV186_001574"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532952.1"
                     /translation="MLTFDFYNKGYCGSQLNEEKFGELSKRAERKILALIGLKKEQVK
                     NLPLDILEAVKMAVCAQIEYLNAIGVESAIGVTSVTQAKVGNFSYTDGKKATVSASVG
                     SVGVSPDVLDYLLPSGLLYKGVNTRW"
     gene            10664..11008
                     /locus_tag="TV186_001575"
     CDS             10664..11008
                     /locus_tag="TV186_001575"
                     /inference="COORDINATES: protein motif:HMM:NF022130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532953.1"
                     /translation="MVKEVKPIPKELLVDTVTYLAVGNKDSWGAETVVSTELSQVLVQ
                     PRSSIQRGQQNESNSYELLLFFDCVNSLPVDHQFKVDDKISYLGKEYRIASVEVLKAF
                     DQSPHHYEVMLE"
     gene            11005..11358
                     /locus_tag="TV186_001576"
     CDS             11005..11358
                     /locus_tag="TV186_001576"
                     /inference="COORDINATES: protein motif:HMM:NF022564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532954.1"
                     /translation="MIGFKVEVIFNASKLIAKSEASAKTARFALSGQIKKDSDKYIPA
                     REWNLRDSGRVTERSVSWHTPYARRLYYNPQYNFSKDKNPNAQGKWFEVAKANHAEHW
                     YELTKKAYGAEFRGD"
     gene            11361..11729
                     /locus_tag="TV186_001577"
     CDS             11361..11729
                     /locus_tag="TV186_001577"
                     /inference="COORDINATES: protein motif:HMM:NF024103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532955.1"
                     /translation="MTFIDFLLRKVQEVSGAEPVLGIMGNSDKVAIIPMAGNFDNRAL
                     DESKIRIFTFQVLAKSKKQQEAFLTTENLVNGLDGLSNEPFTGGYLIKLECTTTTNFV
                     EKDSDKNYLYTALFRAELGG"
     gene            11733..12230
                     /locus_tag="TV186_001578"
     CDS             11733..12230
                     /locus_tag="TV186_001578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532956.1"
                     /translation="MAADKPTFYLQSEHKLEISEDGKTWMRLAGGISELEPDGNEEVS
                     QDAYLDGSESDVTGGQLVLALTGHRLVGDKAQDWIYARQFRYGGKRRGFTRWTLPGGK
                     TQFTFASTFANIKGPSGAANGKGEIEFEIHSNETLVPNKVVVEVTKTNKELASEALGL
                     ERQER"
     gene            12250..12657
                     /locus_tag="TV186_001579"
     CDS             12250..12657
                     /locus_tag="TV186_001579"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532957.1"
                     /translation="MVRQFEFKKTVEEIEIAGEIYLLPLDDDNLLRIQRDFISYGKEI
                     EELQKVEVEKGDPDDLADNHKQQLLVMKKVIESPFGEGSFEKLYEASGHSLMNMVDLL
                     DYLVELVAEKVEQNKARATKAKEKYYSSKRKKK"
     gene            12665..13282
                     /locus_tag="TV186_001580"
     CDS             12665..13282
                     /locus_tag="TV186_001580"
                     /inference="COORDINATES: protein motif:HMM:NF018553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532958.1"
                     /translation="MKLTETYEVLADAFEFGGHIVTVDLAFDVVLRVMELLADAEVND
                     YAKIVWTLDMLLPYFDRTELSFDEEFEIFEYILKTFIYEQEDGEDDSLGGMSQTKTMH
                     FEKDAELIFASFFQSYHLDLFEQQGKLHWRKFMSLLMNLHKDTPFKEVVSYRVMKVPN
                     KDEASEEYIKHVKKMKRIYSLEDESEHQALNDDKLSALAARFGGE"
     gene            13283..15730
                     /locus_tag="TV186_001581"
     CDS             13283..15730
                     /locus_tag="TV186_001581"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1532959.1"
                     /translation="MADGSVIIDTLLKTEKFNQGVGKLQGKLAGLGSKLTSIGTGLTL
                     GLTAPIVGIGAASLSTFTTFESQMNRVKAISGATASEFRKLEDQAIKLGASSVFSATE
                     VAQAQEMMASAGFKVVDILKAMPGVMSLAAVSGGDMALASEAAATAVNMFGLEAKDAA
                     HVADVFAQAAADTNAEVGDMAEALKYAGPVAGALGISLEETAAAIGIMSNAGIKGSQA
                     GTTLRTSLSRLTDPTKKMRGIMSELGLEFFDVNGKMKSLSGITKELQTKMGDLTDSQK
                     SAAISTLFGKEAMSGMLALVNSAPGALDKQTQALINSNGAAKEMADTMNSGVKGSIEE
                     LKGSLETAGISIGKILAPALTSVIGAITSLVNWFNNLSPTMQNVVVVLGSLLAAIGPV
                     VLIIGVVTTQIAAFQQGVGLVFNAVKGLQAAFAFLTSPIGLVIVAIGALIAVFVYLWN
                     TNEQFRTKIIEIWTAISNFLQPIIQFIGNFIRETWTQLATFWNENQATIMTIAQTTWS
                     FIQTIFTTAIEMIKLAVSVFLGLLQSTWSVTFNSLKVIAQVAWAFISNVFKGSLGSIL
                     AVASAIFEQIKSTIDLAMKIIQNIIKIILSAIEGDWDGVLEGIKGIVSAFGDFIQSTF
                     SNMMDTAKRLVGAGIDTVKGIFDSLWNIDLFGAGQAIINGFLNGLRSMWGAVTDFVGG
                     IASWIAANKGPISYDRVLLKPHGKAIMDGLGNSMKTNFKDIQKDVSGMADDLTRSFQI
                     KRFNGFLPEKYTTKLDELKKYAQATLGGMILAPNMAVQPTVVVNISNEADSDIIRQKV
                     NAKNAQDAIINQLFKKG"
     gene            15734..16495
                     /locus_tag="TV186_001582"
     CDS             15734..16495
                     /locus_tag="TV186_001582"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1532960.1"
                     /translation="MFSIEFLDGERLSADERGWKVKEMSSSGLEQNVVSESPKMRSGR
                     LVYGLYHGIKTYQLVFTKIIKDTLDYSRLVDEVNYYFLRDEPYYLYRDFRKKADRVDL
                     PKKRAKVFTKSIDHQKNGLKVEFTAKLESYELPYEEDTEVQRVTWTATHSWHNKGGHR
                     LDPRYCPMKMTITVSGSGAELKVLFNGQPYFWYKKSVKQGDIFIIDGTDVEKNRYNCF
                     EDCHKQTSFLKTGNNRIDIQGASCEALFEYRLLYL"
     gene            16506..>18070
                     /locus_tag="TV186_001583"
     CDS             16506..>18070
                     /locus_tag="TV186_001583"
                     /inference="COORDINATES: protein motif:HMM:NF018329.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1532961.1"
                     /translation="MQVKTKQGVFYVNADYTVVEKQGDYPKLTCTIPIKGNETWIADC
                     QELDRLYPAGEQDEFIIINPIKVTKGSSYDLEITAIGAFHFEFVKARLYEELPERMYT
                     LDYLLDLLFKDSRFSYKLQGDYSTRRFSGFGDDNKLTLFHHLMERFQTEFKVVGKVVL
                     VNTKVGKDTGFQFRYLRNIKDTKYSVDVTNLMTYVKGYGAWFDENDHSKGRLIVDYES
                     PLSKEYGKLDGKPVVDERMSLKESLIKKCKLAVDRSVSVSLTTTLVSLKQQDYQGAAR
                     IGDSIWFIDERISIEKKIRFSVVTTYYNAYDDILKQDVTLGDKDTYSRYQSLENSSQT
                     ETNDFQKAMSSKLAEVQDDVKKTHILVSGTTRIFFSTEFPQDNPKGTIKEDDILYRNH
                     DGTTLMYRWNGVQWELVPLVNDPDRWREELEKQISEAVEKLKQEQKVINQRTDKELEE
                     FRDTLKNLSLPEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTD
                     GKTRYNKNLLVGDP"
BASE COUNT         5894 a         3143 c         4123 g         4910 t
ORIGIN      
        1 acccacgcag ttactgataa aaatttattt acagagtata catttgcgac gcagcaagat
       61 gccgagaatt atatcagaga cttagagcta aacggatcta agtgtgccct ttgagtatta
      121 tgagaggaga tttgcaaaat gatagacacc gatacacttg cagcagtacg ggaggctgat
      181 catgactaaa aacgactttt taacaggttt tgtacttata cttttagctg cttgcatttt
      241 tgcagcagga tttgtgattg gatctgactg tagtagcgag cactacgagc aacaaatgac
      301 aggcttgcgt atgcagcttg ttaacacgca gcagcagctt aagcgtgcga gtgaggatag
      361 agcaaggcgg actaaaagga ttgcggatct gaccgggaat ggaggatagg gtatgatcga
      421 cgaaatcgaa ctcgacctac aaaaaccaga aatcccacag tttgtcgctg actacataga
      481 tgatatgcac aaaaacgcac gtacattgag atacgctttt aaatacatgg aaagtaacat
      541 aaaaatgcac aaatggtgtg tttttgaaag gcaagaaacg tttgttaatg cttttttata
      601 cggctacaca ataaaaaaag aaaagctgta tattgttgag atccctaatc ctaatagtgg
      661 catagaacac aaacatattg cactagcaag gttagcgaat ggaaaacttg gattttcaga
      721 gatcatagat actgattttt attcaagaga agatgtccga ctcaccgagt cagaaatccg
      781 caaagatttt gattgggcat ggagagaggg gtttgctaaa gaggtgacgg aatgagcaga
      841 gataaaacca gaatcaggaa cattgtgaag tccatgaaac agttaggtgc tagcgaagaa
      901 gagacagacg aatacatgta tctatgcgtg tttaaaaagc ctcacgtcat agctcaaatc
      961 cgtaaaaagg ctaagatttt cagaggcgaa gggtggtaac agatggcata tttacgagaa
     1021 gaaagagaaa cagttattca ttacgacgaa ttggatgact gctggacttt tgaaactaac
     1081 gtccgtaggc atattacgaa aatagaaaaa cgcatcgaac tgtacgagat tctctcagag
     1141 gaattcgatg accgaggaag gcgtatctat atctgtgcga aaatgaagac aggaactgtc
     1201 agtccctttg cgaaaccacc aagaaggaaa tagctataga atcgatttta agcttcaaaa
     1261 acatggcaag aacgcacttc tgggaacgtg aaacacctag ctaatataaa tgtaccctag
     1321 aacaatttaa atcgaaaaaa tgattagcta cataggtttt aatcggctta tgtggcatag
     1381 accgaaatta aacacagaag gatgtgatga caatctcctt acacccaaaa aatctaacgc
     1441 tggttatcgg tcaccagcta ttatccaagg cgctaatact gacatcgtgt gcctgagctg
     1501 gcttataaaa aacgaaagag agggcttttc tccacacaaa aagacgtcca tgcgaacgcc
     1561 tccttggtta tatctgttaa caccattata ccacactgag ggggctttca tgacgttttt
     1621 tcctgagatt gatatccaaa aaacaaaatc caatgccaag cgtaaattga aagagtatcc
     1681 acgctggcgg cggatagcta acgatgtaga tactcaaaaa gttacagcta cttactcatt
     1741 tgagccaagg caacctcatg gagtccatag caagcctgta gagaggttag cacttaatcg
     1801 tgtgtcagcg gagcaggagt tagatgcgat tgagcaagct gtcagcatga tactagagcc
     1861 agagaggcgc aggattttgt acgataaata cttatcacct tataaaaaag cggacaaggt
     1921 tatttataca gaattgtgta tgtcagagag cttttattat gatacgctcg atatcgcttt
     1981 attagctttt gcagagctat atagagaggg gtctctgatt gtcgagcaag gagtttttag
     2041 ctagttttta tacagtaata taatagtttt tgtacaaaat agcgtgttaa tatagtatca
     2101 tagcaaaata acaaaaagag ataaccattt taccaattga ctatttattt agtcgccaac
     2161 tttaactacg atcaaacttg ttattttgaa ggtacatggg acgtgcaggt tcgaatcctg
     2221 ccgtctcaat accagctatt tccaaaatgg aaacagttgg aaaagacaaa ccccccattc
     2281 ctttaaaggc agatacgttc tgatatgggg ctttttatga ttaactgcaa gtaaaacaag
     2341 ggtcgcaacc ttgcttgtgg ttagtagacc tagtggtcgt ttatgcacgt tcgattcgtg
     2401 caaggtctgt tgggttgatt gcaataatcc ttttgtggac gcacaacaaa aatgtgatgt
     2461 aagtcacggc taaggtttgg gcggcgatag aatagatgcg caactatcgt tgggtcacgt
     2521 ctcagagttt gcatagttaa tattaaccga tgggcacacc ctgcgtcagt gggttgttta
     2581 tggatagctt agcaaagggg ttaatgcgac caactgttta gtttggtagg cgtgagttcg
     2641 aatctcacac tattctttca ggaacatgaa ccgtgattgg aaaacggtag aggtagcgcc
     2701 ttgataattg gattgtcgac ggtctgatta tatgtgtcgg ttcaattccg actgttcctg
     2761 ttctagtcac caattgtggt ggctttttat tatgtcacga ggaggtgatg gaaaattgct
     2821 aagttaacta taaaacaaca aaaatttatt gatgagtaca tcatctgtgg aaatgcgaca
     2881 gaagccgctc ttaaggcggg ttatagcaaa aaaacggctg ggcaaatcgg tgagcagaac
     2941 ttgaaaaaac ttgaaataaa atctgccatc aacgaacggc taaaacaact cgaaagcagt
     3001 aaaatagcta gtgcaatcga gatcctacaa gttcttactg ccgttcttcg gcaggatttg
     3061 acggaggagg ttgttaccct taatcctgta acaggtgagt acgttactat gcagaaaaaa
     3121 cctagcatcg cagaagtcat aaaagctgct ggtgagttat tgaaacgtta tcctatccaa
     3181 gaacaaattg aaaaaatcaa gcaagaaaac gagttgttac gccttaaaat tgaaaccgtc
     3241 aaaggcgcca agcctgatac ccatttgatg gaaaaactgc tggaggtaat cgaagatggc
     3301 ggttaggata aaaaagttat ccacaaaaca aaaagacatc attagacgcc cttttaacta
     3361 cgaattagag gtcaatgagg gaacacccag aagtggaaag accaccgctg ggcattttcg
     3421 ttatgctagg tatctgattg agtcagaaga tgaaaatcat cttgtgactg cttataatca
     3481 agaacaagct tatcgtttgt ttattgatgg agacggtaca gggctgatgc acatctttga
     3541 cgggaactgc gaaatcaaac atgatgagcg aggagatcac ctgcttgtaa caacaccaaa
     3601 aggtaataaa agggtttatt acaagggtgg aggtaaagtt aactcagtcg gtgctattac
     3661 aggtatgtct ctaggctcag tggtcttttg tgagattaat ctactgcata tggattttat
     3721 ccaggagtgt tttaggcgta cctgggcggc taaactgcgt tatcacttag cagaccttaa
     3781 ccctcctgcg ccacagcacc ctgttattaa agacgttttt gacgtccaaa ataccagatg
     3841 gacgcattgg accatggacg ataatccaat attaactgcg gagcgcaagc aaaacattat
     3901 caatagcctc aaaaaaaatc cttatcttta taaacgagat gtactcgggc agcgggtgat
     3961 gcctcaaggt gttatttatg gtctttttga catggaaaaa aatgttctag acactttgat
     4021 tggcgagcca gtggagatgt atttctgtgc agatggtggg caatctgatg ccacatctat
     4081 gtcttgcaac atcgtaacaa gagttagaga taatggcaag ataagtttta ggcttaatcg
     4141 gacagcgcac tactatcata gtggagcaga tactggtcag gtcaaagcca tgtcaacata
     4201 cgccagagaa cttaaggctt tcattgactg gtgtgttaaa aaataccaac ttcggtactc
     4261 tgatgtcttt attgaccctg cgtgtaaggc tttgcgcgag gaattacatg ccattggtat
     4321 tctgacgact ggagcgccga acaacgctca cgacgtaaac agtaaggcga aaggtatcga
     4381 agttgggata gaacgtggcc agactttgat ttcagacggt gatttttatc tagtaaatca
     4441 caaagaggaa aaatatgatc attatcattt cctgaaggaa ttagggcttt atagccgcga
     4501 tgataaaggc aaaccaatag acgcaaacaa ccactcaatg gacgaattta ggtactcggt
     4561 caatgttttt gtgggacgat acaaaatgaa ataggaggta gtcatgttta gaaacctctg
     4621 gactaaaata aaaggggtga tgcaaaaaat gggattgata aaaggtttga aagatttgaa
     4681 cctgcaccgc gaaattgaac tgtctgataa gcattatgat agtatccaaa tttggaaaga
     4741 gttgtatcaa ggctatcacg ataaaataca cgattactat gagaaatcta tcttagatgg
     4801 tcgtaaaaag aagaagcgtt tgactttgaa tatgcctaaa gttgtgacct cagagcttgc
     4861 tacattgatt tttaatgaaa aatgtgaaat taacattggt tctgaaaatg agagtttgac
     4921 aaagctcatc actgaaacgt tagagaaaaa taattttact caggagtttc aacgcttctt
     4981 agaatatagt ttcgccttgg gaggtatggc aatcaaagca tatctcaaaa aggacggtac
     5041 tatcggtctt aattttgtac aagcggatag ttttattccc atttcgtggg ataatgctgg
     5101 gattagcgaa gccgtatttg ttgatacgca gcatcgtgga aaatacaagt acacgcattt
     5161 ggagtggcat acttgggaaa gtgagttgta tgtagttgct cacgagttat ttagaactga
     5221 caagtcaaat gatgatgttg gcattcgcgt accgataaca gagatttatc cagatttaaa
     5281 atcacaagta gtcatcgaaa aactatcaag accgctattt gtttacctca aacctaattc
     5341 ggcaaacaac attgatctat caagtccgct agggatttca atctatcaca attcgtttga
     5401 taccttgcga gcgattgata ttgcctacga tagctttgag cgtgagtttc gacttggccg
     5461 taagaggata ttggttccag cgactgccat tcgtactgta gtggatagcg aggggaattt
     5521 ccaccgctat tttgacgcaa cagacgaaac atatgaggct ttccacacag gtgaagacag
     5581 caaaattcaa gatatcaaag atattagtgt tgaattgcga gttgatgaac atattgcagc
     5641 tattaacgca ctgttgaact tacttagtat gcagattggc tttagcccag gttctttcag
     5701 tttcgatgga gtatcgggtg tcaagacagc caccgaggtt atctctgaga attctaagac
     5761 attccgcacg aagcaatctc atgaaacgat ggtagaagca acattgaaaa atcttgttgc
     5821 gattatcgtt gattttgggg atctttatgg tttgatcgag ggtgagagta agtataatgt
     5881 aactgtaacg tttgacgact ctattgcgca ggacagaacc caggacgctc agtattatat
     5941 agggttggtc gcagctgggt taatcagcaa gaaaaaagct atgatgaagc tgtttaatct
     6001 gtcagaagaa gatgcagagt tggaaatcca aactatccac gaggaaagcc ggacaacaaa
     6061 cgatatgtca attgatttat ttggtttgga cggtgatgct tagtggatta tgatactcat
     6121 atccagctgt cttttgactt aatagagctt tattctgatg tcgaacgtga attgttgacg
     6181 tcaataggtc gcaggtttgc aaaacactat gacgaaatgg tagctggcga catcatggat
     6241 tggcaaatta ggcaattact cgaagttgga gagctgagaa aagagcacat cgaaatcatg
     6301 cgaaaaagtg cacgcgtgag tcgtgagcgt atgattgaga tgctgacgga ggcaggttat
     6361 acctccgcag gaaggtatga ggattttttt aaagaggcat acgttaaagg tttaatcaag
     6421 ctcaatccat ctgctgcaga caacagcatg aggttgttgc gagtgttaaa tacttacatc
     6481 aatcaagctg aggacacact taatcttgtc aatacgacca tgttacagtc tggccaagat
     6541 acttttttag atacagtcaa tcaagttgtt gcttatgttt ctacaggtat caagacccca
     6601 caagttgcta tgcgtgacgc tctaaaaaat gctggtcaaa agggccttac agtctttcgt
     6661 gctaaaaatg gcgcccagtg gtcaacggag acttatctca atatgatcac tcggacgatg
     6721 aactctaaca tttctaacgc tatggaagat gagcgtaggc atgagtatgg tgttgattac
     6781 atcgaggtat ctagccatgc tggcgcacgt ccaaggtgtg ctccttatca aggtcggata
     6841 tattacgatg gtgtcggaga tgatccgcta gagaaatacc cgcacttctc agagacttct
     6901 tatggcgaag ctgctggatt gtttggcgtt aattgcggtc atcataaata tccttacgtc
     6961 ccaggtatga gtaaacagac ctttttccct tacagtaaaa gcgaaaacga taaaacctat
     7021 gcagagtcgc aggtacaacg taaattagaa cgggaagtta agcagctgaa acgggaacga
     7081 gcaattctaa ctgctgcgaa ggacaaagag ggggctaaat tagcttctca acgcttggag
     7141 aacaagtggc aggaattgcg tcagtttact gctcaaacag gcagaacgag acgatacgac
     7201 cgcgagaaat cgctaaatac tattttgtct gaggacaaga aaaaagccat tgtcaaagat
     7261 aatttgaaaa tcagagatga gtatcgagcg attaagaaag ctatccctga agtagctcct
     7321 aaaaatcttg aaacctatta tgatatgcgt tataatggtg gcaagatata cgaggattta
     7381 gttagggatt acaaagacta tataagatgg tctaaagctg aatttcctac taaaaaatct
     7441 tttgaagggc atattgatag tcacttaaaa gagtttccag gattgactgg taaacaatat
     7501 cagaaaaagg ctgctgactt attatctaga ccgataactg ataatatttt aggttatgat
     7561 acagattcta gacgtgttag gtatgactta gaaaataaca tttttgcttt agggcgcgtt
     7621 aaacaaggta cgattacgac tatgctgaaa ccaaaggaag gggttgatta ctttgacaat
     7681 gactggaaaa gagagtttga taatcttaaa tgatttagaa tatgtccatt gtcctgtttg
     7741 tggaactttg accgaggttt atgatatttg cgatacttgt aaatggcaga ataccggtga
     7801 gacaaatatt gatggcggtc ctaattatat tacacttgag gaagcacgac gaaggtgggc
     7861 aaatggtgaa cctttgcgca acttttttaa agaccaataa tacaagcact gtaacagtgc
     7921 tttttttgta ctcaaaaaag gagagagtaa aatgaacaaa cgaattgaaa agaagcgtcg
     7981 cacacaaatg atgttagaca gaatcttgcg cattgtagaa ttgatgtcgc aagcaactga
     8041 cgacaacttt gctatcttgg aaaagcgctt agaaaaagct gaaaaacgta acgaagagct
     8101 tatggaaatc atcttagtaa acgttaaaga ggtaaataac cgctttgacg agctagaaat
     8161 ctgccagaag attgttgaag atgatgtcgc agagctcaaa aaagctaaga aaaaaggctg
     8221 gttcagccgg aaataactta atcgtgtcga attcgatgcg gttttatttt gccctgccgc
     8281 atggcgataa actaggtaaa aataaaagaa agaggtctaa aatggctgtt attatcgtac
     8341 aaacacgagg cggagatatt gaagttccca ccccattacc agcaatgcaa gctaataaag
     8401 cgattcaaag tcaattattc gataaggagc tgactttttt atgcgtggat aatcatgctt
     8461 ttgctaaaac tgaggtttta cacgttttgg tcgaaacaga agaagatgaa gaattaccac
     8521 agtcaaaaca taaggaggaa gaaacatgct acatggatta aaacaccgtt tgtttaaact
     8581 agccccagat actggagcag gcggaggcgc tgaagttact agcgagacta acgctgaagc
     8641 tggacgagtt gagcaaacag tatcgcaaca acaagctgat ccggttgata ctgaggcaat
     8701 caaaaatcaa gcaattaatg aggttctaag tcaactaggt gtttcttcgg tagaagatgc
     8761 caaagcaaat ctagcttctt ggaatgaata tcaagaaggt cagaaaacag agtttcaaaa
     8821 aattcaagat agtttgactg tggctaataa ctctttggct gagcgcgaca ctatgattgc
     8881 tagcttacaa gctcagttag ctgctgctca aatgggagtg cctgcggaaa acacctccga
     8941 tgttatcact ttggccaata gtttggtcca cgataaaaca gacatcaatg cagcgattac
     9001 taccgtactt gagaaatatc ctcatttcaa aggaggtgat gccgatgtag ctgataaacc
     9061 taactttgtg actcaaactc agagtcaaac ggaaacgacg gaagacgctt tttttaaagc
     9121 gttaggacta acaattaagg aggactaata tgtcaatcaa ttatattact aaacatgaag
     9181 gaatattcga aaagaaacta atgcaaggcg ctttgacgtc taacttagag acaccaaaag
     9241 tcaactggtt aggtgcaaag tcttttgagc taccaaccat ctcggtgact ggctataagg
     9301 cgcacacacg ctcaaaaggg tataacgcag gtactgtatc taacgataaa aatacttata
     9361 cgctcggctt tgatcgtgac gtagagtttt ttgtggataa ggcagacgtc gatgagacta
     9421 accaagagct gtctatggct aacatctcaa acacttttat cacagagcat gcaacgccag
     9481 aagttgacgc ttatcgcttt tcgaagattg ccacaaatgc gatcgataat agccatttta
     9541 agcaggaaga tgactactct actactaatg tttatgagcg cttaaaagct gctattttgc
     9601 ctattcgcaa gtacggagct ggcaatatca ttatctatgt ctccagtgag attatggact
     9661 ttttggagcg ctcaaaggac tttacacgct caatcgcgac aacatcaccg caagggattg
     9721 atactcgtgt gacatctctt gacggagtgc agctcataga ggtttgggac gatgcccgct
     9781 ttaagactaa atttgatttt acgacaggct ttgtcaaaga tggcagcggt aaagacatta
     9841 actttttgat tgtggccaag cctgcggtta ttgcaaaagc taaatttaac tctatttatc
     9901 tttttgcacc aggtcagcac accgaagggg acgggtatct atatcaaaat cgcttgtatc
     9961 acgacctttt tgtgcttaaa tctaaacaag atggggttta tgtatcccat aaatcagctt
    10021 aggaggttaa cgatgaaaac atacgagaag gacaatcaag tctataaagt acaagaaggc
    10081 agcgagctgg aaattcagct gattgccgac ggctttaaag aaattattga agcaaacgaa
    10141 aaggaaactg atatcactaa aatgaagctt gataagctaa aggcttatgc tgaaaatgaa
    10201 ggcattataa ttcctgaaga tattaagaaa aaagaagatg ttttagcttt tattaaggaa
    10261 cagcagcaga gaggtgagta gtgatgctca cctttgattt ttacaataag ggatattgtg
    10321 gctcacagct gaatgaagaa aagttcgggg agctgtcaaa acgtgctgag cgtaaaattt
    10381 tggcacttat tggcttgaaa aaggagcaag tgaagaattt gccacttgat attttagagg
    10441 cggtaaaaat ggctgtctgc gcccaaattg agtatcttaa cgcaataggc gttgaaagtg
    10501 ctatcggagt aacctctgta acccaagcta aagtcggcaa ttttagttac acagacggaa
    10561 agaaagcgac tgtatcagct agtgttggct ctgttggtgt tagccctgac gtgctagact
    10621 atctgcttcc gagtggattg ttatacaagg gggtgaatac gagatggtaa aagaagtcaa
    10681 acctatccct aaagagttat tagttgacac agttacttat ctagcagttg gcaacaaaga
    10741 cagctgggga gcagaaacgg tagtatctac agaattgtca caggtgttag tacaacctag
    10801 aagcagtatc caacgtgggc aacaaaacga gagtaatagc tacgagttgt tactcttttt
    10861 tgattgtgta aactcgttac cagtagatca tcagtttaag gttgacgaca aaattagtta
    10921 tctaggaaaa gagtatcgta tcgcaagtgt tgaggtacta aaagcttttg accagtcgcc
    10981 acatcactat gaggtgatgc tagaatgata ggttttaagg ttgaagtcat ctttaacgct
    11041 agtaaattga ttgccaagag tgaagcatct gcaaagacag ctcgctttgc tttaagtggt
    11101 caaatcaaaa aggatagtga caagtatatt cctgctcgtg agtggaatct gcgagatagc
    11161 ggaagagtaa ctgaacgctc agtatcttgg catacaccgt acgctagacg actctactac
    11221 aatcctcagt ataactttag caaggataag aatccgaatg cacaaggcaa gtggtttgag
    11281 gttgctaaag caaatcatgc agagcattgg tatgagctaa caaagaaagc ctatggtgct
    11341 gagtttagag gagattaatc atgacattta ttgatttttt gctcagaaaa gttcaagaag
    11401 tgagcggagc ggaaccggtc cttggcatta tggggaatag tgataaggtt gctattatcc
    11461 ctatggctgg aaattttgac aatcgagctc ttgacgaaag taagattagg atttttactt
    11521 tccaagtttt ggccaagagt aaaaaacagc aggaagcttt tttgacaaca gaaaacttgg
    11581 tcaatggtct agacggtcta tcaaatgagc cgtttactgg aggatatctc attaagctgg
    11641 agtgtacgac gaccactaac tttgttgaaa aagatagtga caaaaattat ttatatacag
    11701 ctcttttcag agcagaatta ggaggataag aaatggcagc agataagcca actttttatt
    11761 tacaatccga gcataagctc gaaatttcag aagatggaaa aacttggatg cgactagcag
    11821 gtggtatcag tgaattagaa ccagacggaa atgaagaagt atcacaagat gcttatcttg
    11881 acggctctga atctgatgtt acaggaggtc agctagtact agccttaact ggacatcgtc
    11941 tagtaggaga taaagctcaa gactggatct atgcacgtca attccgatat gggggcaaac
    12001 gtcgtggttt tacgcgttgg acattgccag gaggaaaaac acagtttacc tttgcctcta
    12061 cgtttgcaaa tatcaaaggt ccatcaggag cggctaacgg taaaggtgaa attgaatttg
    12121 aaatccattc gaacgaaaca cttgtaccta ataaagtagt tgtagaagtc actaagacaa
    12181 acaaagaact tgcgtctgaa gcacttggtt tagaacgtca agagcgataa gtagaaagga
    12241 tagtcagcaa tggtgagaca gtttgaattt aagaaaacgg ttgaagaaat tgagattgca
    12301 ggggaaatct acttactgcc tcttgatgat gataacctct tacgtatcca acgtgacttt
    12361 attagttacg gaaaagagat cgaagaactc caaaaagttg aggtagaaaa aggagatcca
    12421 gacgatctgg cggataatca taagcaacag cttttagtaa tgaaaaaggt catcgagtca
    12481 ccatttggag aagggagttt tgagaaactt tacgaagcat cagggcactc tttaatgaat
    12541 atggttgact tattggatta tcttgttgag ttagtcgctg aaaaagttga gcaaaataag
    12601 gctcgtgcca ctaaagcaaa agagaagtat tactcctcga agcgcaagaa aaagtaggta
    12661 gcttatgaag ttgacagaaa catatgaagt tcttgctgat gcttttgaat ttggcggtca
    12721 tatcgtaact gttgacttgg cttttgatgt cgtgttgcga gtcatggagc ttcttgccga
    12781 cgcagaagtc aatgactacg ctaaaattgt ctggactttg gatatgctct tgccatattt
    12841 tgatcgtacg gagttaagtt ttgatgaaga atttgaaatt ttcgaatata tcctaaagac
    12901 gtttatctat gaacaagaag acggagaaga tgacagttta ggaggaatgt cacaaacgaa
    12961 aacaatgcat tttgaaaagg atgcagagtt aatctttgcg tccttttttc aaagttatca
    13021 tcttgaccta tttgaacaac agggaaaatt gcactggcga aaatttatgt cactgctcat
    13081 gaatctgcat aaagacactc cttttaagga agttgtcagc tatcgtgtca tgaaagtgcc
    13141 taataaagat gaagcatcgg aagagtatat caaacacgtc aagaagatga agcgtatcta
    13201 ttcgctagaa gacgaatctg agcatcaagc gctaaatgat gacaagcttt cagcgttagc
    13261 agcaaggttt ggaggtgagt agatggcaga tggtagtgtt attattgata ccctgctaaa
    13321 gactgagaaa tttaaccaag gtgtagggaa actacaaggt aaattagctg gattaggatc
    13381 aaagttgacc agcattggta ccggtctaac tctaggctta actgctccta ttgtaggaat
    13441 cggagcggca tcgctcagca cgtttactac atttgaaagt caaatgaatc gtgttaaggc
    13501 gatttctgga gcaacagcaa gtgagttcag aaaactagaa gaccaggcta tcaaacttgg
    13561 agcttcctct gtttttagtg cgacagaagt agcacaagct caagaaatga tggcttctgc
    13621 aggttttaaa gtcgtcgata tcttaaaagc aatgccgggt gttatgtctc tagctgctgt
    13681 atctggtggg gatatggcat tagcaagcga ggcagccgca acagctgtca atatgtttgg
    13741 acttgaagct aaagacgcag cccatgttgc agatgttttt gcacaagctg ctgcggatac
    13801 taacgcagaa gttggagata tggcagaagc cctaaaatac gccggacctg ttgctggggc
    13861 tttagggatt agcttggaag aaaccgcggc agcaattggt atcatgtcta atgcaggcat
    13921 taaagggtca caagcaggaa caactttgag gacaagcctt tcacgactta cggatccaac
    13981 taaaaagatg cgaggaatca tgtccgaatt aggacttgaa tttttcgatg ttaatggaaa
    14041 aatgaagtcc ttatctggta ttaccaaaga acttcaaacc aaaatgggtg atttaactga
    14101 tagtcaaaag agtgcagcta tctctacttt gtttggtaaa gaagcaatgt ctggaatgct
    14161 tgccctagtt aattctgctc ctggcgcatt agacaagcaa acacaagcac ttatcaattc
    14221 aaatggtgct gctaaagaaa tggcagacac catgaatagt ggtgtcaagg gatcgattga
    14281 ggagcttaaa ggttcgcttg agactgctgg aatctccata ggtaaaatat tggcgccagc
    14341 cctaacgtcg gttatcgggg cgataacaag ccttgtgaat tggttcaata acctaagtcc
    14401 gacaatgcaa aacgtggtag ttgtactcgg aagtttactt gctgccattg gaccggttgt
    14461 ccttattata ggggttgtta ctactcagat agcagctttc cagcaaggcg tcggactagt
    14521 ctttaatgct gtcaaaggat tacaagctgc ttttgccttt ttgacgagtc ctatagggtt
    14581 agtcatcgta gccataggtg cactaattgc cgtatttgtt tatttgtgga atacaaacga
    14641 acaatttaga acgaagatca ttgagatttg gacggctatt tcgaactttt tacagcccat
    14701 catacaattt attggtaatt tcataaggga aacgtggact caattagcta ctttttggaa
    14761 cgaaaatcaa gcaactatta tgacaatagc ccagacaact tggtcattta tccagacgat
    14821 atttacaaca gcaattgaaa tgataaaatt ggccgttagt gtttttttag ggttattgca
    14881 atcaacgtgg tctgtaactt ttaattctct taaggttatc gcacaggtcg catgggcttt
    14941 tatttccaat gttttcaagg gaagtttagg gtccatactt gcggttgcat ctgctatatt
    15001 tgagcaaatt aaatcaacga ttgatcttgc gatgaaaatt attcaaaata tcatcaaaat
    15061 catactatcc gcgatagaag gtgattggga cggtgtatta gaaggtatca aaggaattgt
    15121 ttccgcattt ggagatttta ttcaatcaac tttctcaaat atgatggata ctgctaaacg
    15181 cttagtcgga gctggaatag ataccgtaaa aggaattttc gattctttgt ggaatattga
    15241 cttgttcgga gccggtcaag cgattattaa tggattctta aatggtttgc ggtctatgtg
    15301 gggagctgtc acagatttcg ttggcggtat tgcaagctgg attgcagcaa acaaaggtcc
    15361 catctcatat gatagggtac tattgaagcc gcatggaaaa gctattatgg acggactcgg
    15421 taatagcatg aaaactaact ttaaggacat tcagaaagat gtttctggca tggctgacga
    15481 tttaacaaga agttttcaaa tcaaaaggtt caacggtttt ttgccagaaa agtatactac
    15541 taagcttgat gagcttaaaa aatatgcgca agccacgctt ggcggaatga ttttagcccc
    15601 taacatggca gttcaaccga cagtcgttgt taacatcagc aatgaagcag atagcgatat
    15661 catcaggcaa aaagtcaatg ctaagaatgc acaagatgct attattaatc agttattcaa
    15721 gaaagggtaa aacatgttca gtatagagtt tttagacgga gagcgactaa gcgccgatga
    15781 acgaggatgg aaagttaaag agatgtcctc atcaggactt gaacaaaacg tcgttagcga
    15841 gtctcctaaa atgcgttctg gtcgccttgt ttatggtctt tatcatggca tcaaaactta
    15901 tcaacttgtt tttacaaaaa tcattaaaga tacccttgat tatagccgtt tagtagatga
    15961 agttaattac tattttttac gtgatgaacc atactatctt taccgcgact ttagaaagaa
    16021 agctgatcgg gtggacttgc cgaagaagcg ggcgaaggtg tttactaagt caatcgacca
    16081 tcaaaaaaat gggcttaaag ttgaatttac agctaagctg gaatcttatg aactacccta
    16141 cgaagaagat actgaggttc agcgggtcac ttggacggca acacattcat ggcacaataa
    16201 gggagggcat cgccttgacc ctcgttattg cccaatgaag atgaccataa cagtatcagg
    16261 ttcaggagct gaacttaagg tgctatttaa cggtcagcct tatttttggt ataaaaaatc
    16321 agttaaacaa ggggatatct ttatcattga tgggacggac gttgaaaaaa atagatacaa
    16381 ttgttttgaa gattgccata agcaaacctc ttttttaaaa acaggaaata acagaataga
    16441 tattcaagga gcttcgtgtg aagctctttt tgaatataga ctactgtatt tgtaggaggg
    16501 ttagtatgca ggtaaaaaca aagcaaggtg ttttttatgt taacgcagac tacaccgtcg
    16561 tcgaaaaaca aggtgactat cctaagctaa cttgtactat tcctattaag ggaaatgaga
    16621 cttggatagc agattgccaa gaacttgacc gcttataccc agctggggaa caagatgaat
    16681 ttattattat caatcctatt aaagtcacta aggggagttc gtatgatttg gaaattacag
    16741 cgataggagc ctttcatttt gaatttgtaa aggctcgtct atatgaagaa ctaccagaac
    16801 gaatgtatac tttagattac ttgctcgatc tcctgtttaa agacagccga ttcagttata
    16861 agctacaagg tgattattct actagaaggt tcagtggctt cggagatgat aacaaactga
    16921 ctttattcca tcatttaatg gaacgatttc aaacagaatt taaagttgtt ggcaaggtcg
    16981 ttttagttaa cacaaaagta ggtaaagata caggatttca gttccgctat cttagaaata
    17041 tcaaggatac aaagtactcg gtagacgtaa ctaacctgat gacatacgtt aaaggatatg
    17101 gagcctggtt tgatgaaaat gaccattcaa agggaagatt aattgttgat tatgagagcc
    17161 ccttatccaa agagtatggc aaacttgatg gtaagcccgt tgttgatgaa cgaatgagtt
    17221 taaaagaaag tcttatcaaa aaatgtaagc tagccgtaga tcgctctgta tctgtcagct
    17281 taacaacgac tttagtctct ttaaaacaac aggattatca aggtgcggcg agaataggag
    17341 actctatttg gtttattgac gaacgtatat ctattgaaaa aaagattcgg ttcagcgtag
    17401 taacaactta ctacaatgca tatgatgata ttttaaagca ggacgttact ttaggtgata
    17461 aagataccta ctctcgatat caaagtttag aaaactcttc tcaaacagag acaaatgatt
    17521 ttcaaaaagc gatgagtagc aaacttgcag aagttcaaga tgatgttaaa aagacgcata
    17581 ttttagtatc tggcactact aggattttct tttctacaga gtttcctcag gataatccta
    17641 agggaactat aaaagaagat gacattttgt accgtaatca cgatgggaca acattgatgt
    17701 acaggtggaa tggtgttcaa tgggaattag tcccgttggt aaacgatcca gatcgttggc
    17761 gtgaggaact ggagaaacaa atctctgagg ctgtcgaaaa gctcaaacaa gagcaaaaag
    17821 taatcaacca gagaaccgat aaagagctcg aagagtttag agatacgctc aaaaacctat
    17881 ctttaccaga ggaagccatt aaaaaaatca cagaggctat caaagttgat gatatcccgt
    17941 cgattaaaca gtcatttgat gacttaaaaa ataaagtcag cgagacaagc gagaccgcac
    18001 gattaaacgc tgagattatc gggacagatg gcaagacccg ctacaacaaa aatttgctag
    18061 tcggcgaccc
//
LOCUS       DARYXZ010000048        15817 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYXZ010000048 DARYXZ010000000
VERSION     DARYXZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15817
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(419..2830)
                     /locus_tag="TV186_001584"
     CDS             complement(419..2830)
                     /locus_tag="TV186_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1532962.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVEEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2845..3768)
                     /locus_tag="TV186_001585"
     CDS             complement(2845..3768)
                     /locus_tag="TV186_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1532963.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4095..5642)
                     /locus_tag="TV186_001586"
     CDS             complement(4095..5642)
                     /locus_tag="TV186_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1532964.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6267..7148)
                     /locus_tag="TV186_001587"
     CDS             complement(6267..7148)
                     /locus_tag="TV186_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1532965.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7313..8314)
                     /locus_tag="TV186_001588"
     CDS             complement(7313..8314)
                     /locus_tag="TV186_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1532966.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8455..9627
                     /locus_tag="TV186_001589"
     CDS             8455..9627
                     /locus_tag="TV186_001589"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL1532967.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9631..11115
                     /gene="galT"
                     /locus_tag="TV186_001590"
     CDS             9631..11115
                     /gene="galT"
                     /locus_tag="TV186_001590"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL1532968.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11125..12135
                     /gene="galE"
                     /locus_tag="TV186_001591"
     CDS             11125..12135
                     /gene="galE"
                     /locus_tag="TV186_001591"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1532969.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12212..13255
                     /locus_tag="TV186_001592"
     CDS             12212..13255
                     /locus_tag="TV186_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL1532970.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13556..13699
                     /locus_tag="TV186_001593"
     CDS             13556..13699
                     /locus_tag="TV186_001593"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1532971.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14313..14474
                     /locus_tag="TV186_001594"
     CDS             14313..14474
                     /locus_tag="TV186_001594"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1532972.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
     gene            complement(15066..15404)
                     /locus_tag="TV186_001595"
     CDS             complement(15066..15404)
                     /locus_tag="TV186_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1532973.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVDILRIRSTKTDYLN
                     DLENLFNNIL"
     gene            complement(15394..15681)
                     /locus_tag="TV186_001596"
     CDS             complement(15394..15681)
                     /locus_tag="TV186_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL1532974.1"
                     /translation="MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERV
                     VEEKDLPIKTAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
BASE COUNT         4596 a         3530 c         3110 g         4581 t
ORIGIN      
        1 aattgtacgg ctgctaacct ttttcctaac ccttttagac accaaaaaac tccccttatc
       61 gtttttagtg attgtttttc actgtccact ttaaagggga ggtctagcta ttaaaggcta
      121 ggcggttttg actggaggac tattaggtgt gaggttaatt ggtaaaaact ctttctgtgc
      181 tgccctcctt aggtcatata gactttcttg gaaccaaaac ccacatatag cctacagaga
      241 tccaatgctt taaaagctat gaggtgctaa gctgctgatc aagtcagctt ctctgactgt
      301 tgctgcaagc aaaagcctac taagcgatct taggctgtga ggcgtaagaa caggtcatca
      361 taccaatagc tttttgggga taagctgtga tttgtatgcc ttagctattt tatagtgttt
      421 atttgatttg ttgcaatgtt gtcacatcat aaagcattag gtgtcctttt tggtcataga
      481 atttgacacc ctctggcacg aaaataagat actccggttt aatgcctgct atttcagcta
      541 actgattgat ctgacgttca agagttgccc gatctaaacc ataattagga atatcgtcaa
      601 ataaagactt ggtctgctct atgccatctg cggcagtatc ttgcgctgac ggttcctggt
      661 ctttggttgg cttaatagtg ctttcagctg cgtctgaggt cttattgcct aataattctt
      721 gaaccttttg ccattcatca tgagataact catctttagt aatggttctt aaagagcgtc
      781 caccaactct aggaatgcta aaggaatcat tacgccaaac aaaggttcct tcagcaagaa
      841 cgtccttagg atcaaaaata tagccatctg gagctgcgta ccgacctgcc ttgatagctg
      901 cttggacctc ttcggcagag tgaataattt gccagttttc cattgaagta cgttgatcag
      961 ctggtgtgac attagcaatg actcctccag cttcatcatg atttgggtta gaccaaacat
     1021 caggacgagt attagggtgc tgcatgacat atttgatggt cgcaatctga tccttagtta
     1081 gccatgaata aggtacaaca tggatatgat cgatgtgagg aatgacaaaa gatgtccatg
     1141 tatcataggt tgcattacca gcatgcatcg gtaggctgga tacctctaca gctagctttg
     1201 gctgaacgcc tgtatcaaca atgtcataaa tatagtgttg cttatcctta agcatgagct
     1261 cttgctctgc aaaggcaatt tgtgttaggt ctaaatgctc acgatcatag aaatactctt
     1321 tgccatcttt tgtcatcatg taaccaacct taccgccatt ggttaccttg cgactgacat
     1381 gcttagcgtc aaaggacatg tctttaccgt ctgattgaac taatgccctt gcaatctcat
     1441 ctgcttgacc atgctcctgc agccattgtg caacctggtc aagctcctct tgctctagct
     1501 caccaaagcc catgtaatgg aaatgctcct catgcttagc tgtgatgcct gccttatcaa
     1561 cagaggaaat agatgcctta ctaaagacat aatgatcact cgtgtcataa ggcttgccat
     1621 ctaagccttt accataagcc ttaatctgat ggccaaggaa ttgatgtgta acctcttttg
     1681 cagtctggtc ttgagtagct ggctttggct tagctattgg actgccctgc gtttgacctg
     1741 ctaggtaacg atcagccaag gttatttcaa gggctgacaa ttgctcacga ggaataatat
     1801 ggtagtgatc tccatgagga ataacatagc caaaggcatt ggcaagggtc acctgagttg
     1861 gctcaaaaat gagaccatct tcctcgacgt gcctgtattt cttatccaag ccatgcaatt
     1921 gatccaacaa ttctccaaag gttttatctg caaatgatag gcttggatct cctactgacg
     1981 gcaaattccc agctgggtgg tgaatcgggt taacaggaat atcatatggt ctaggctgat
     2041 ctccttgacc tggtaaaggc tgaccgccaa taacacttgg ttttccgcct tgcttgttat
     2101 tccaataggc ctgcgctgct actagctcac ttggggataa gtccttttta ggaatatagt
     2161 ggaagtgact gccatggggc actaaaaagg catctcccat gtctccaata acatctgtcg
     2221 ggctaaagat atagccatca tcagttgtat agcgtccttg acttcttgct tcgttaacag
     2281 ctgccacctc tgccttactc aagtgggcaa ccttagccaa gcctttttcc ttagcttcct
     2341 ttgttccctt ttcaacctgc tcagcaattt gctgcttggt acgaatattt ttacgcttgc
     2401 ttcctggctt tagataaaca taatacttgc catcaacctt gataatatag ccatctagaa
     2461 tctcgttaac aacatcagac tgtttaaact gataattggg gtccgtcatt aatagctctt
     2521 cactaagaat agcatcatag ggaaccttac cattgtagaa atggaaatga tcaccatgtg
     2581 aggttacata gccttgatct gtgattttaa caacgatttg ctctgcagag atcccctctt
     2641 ctgcgctgat ttgatccatt gttttttctt tggggagggc ttttttgcca tcctttgaat
     2701 caatataggc aatgctatta tctttagatg aggaatttag agccttatgc attccaaact
     2761 gatatgaagc agcattagta gccaataaaa tggccacagc tgatcctaaa acaatatgct
     2821 tctttttcac gttttcatct ccctttattt taagctttgg taaagagctt ccaaattagc
     2881 tctcaaattg tctagatagg acttgttgtt tttgggcgct gcctctagtg gactgagcag
     2941 cttgaccttt gctcctgctg ttttagctat cgccttagca attttaggat taacattatc
     3001 ctctgcaaaa atcgttttta ccttatattc tttaacaaag tcttgaattt cagttagttg
     3061 gcgaggagta ggctcttgct ctggcgaaat accagaaata cctaactgct ttaagccaaa
     3121 gcgttttgct agataagaaa aggctgtgtg ctgtgtgaca aaggttttag atgatgtctt
     3181 tttaaacttt ttagtgtact catcagccag ctcttttgct tccttttgga atgcttgagc
     3241 attctcagtg taaatggcct catgcttagg atctaaacga ctgagctcct tagcaatagc
     3301 gagtgcttct tcacctgcta aaataggatc tgtccaggta tgaggatcat acagggtagc
     3361 agggtcaatg ccatctgtca cctcaatatc ctccaaacca gtaacacgat ctaaggttaa
     3421 agatttggaa gcttcaaaaa cagcaacctt tgatttcttc aaattaggat ccaaatcatc
     3481 agcccaggcc tctagggtgt gagagtgata aacaaataaa tcagcatcgt aaatggcagc
     3541 aacgtcattt acagatggct caaaggaatg aatacctgcc cctgactgaa tcatccgaac
     3601 atcgtttagc tcaccagata ccgcctttgt catggcgtaa ataggataaa agctagtgac
     3661 gatcgtcatg cctcttgact gcttgctttg ctccttgggc ttgctacagg caacaagacc
     3721 tgaaaaaaga gcaagcaaca gtgttaaatg tatccatttt cttttcatat aatctccttt
     3781 gctcattaac cagttatgaa ccggttaatt ttaacagctt tagatgtatt tgtcaaattt
     3841 tttaataaaa aataaaagcc attaaaacga tggcttaatc agcccctaac ctgcttaacc
     3901 tttataagaa gccatagctc tatgataaac tgtggtctgt gacgcatgac ctcactgtct
     3961 gttatcttac tgttgcatga tacgtttaaa aaagatttag ccttcttttt ttagattgta
     4021 gaacggcgct gaacaatcac ttaaccgtca aaaaaacgcc ttgatagctg caagacgttt
     4081 ttacttattt ggttttagct agagcgacgt tttgtcacaa gaccgatgac agctgcaagg
     4141 cctattaata gaactcccat gaacgctacc atcggcgctg ctgattcacc agatcttggc
     4201 aaagccttag tctctttttt accttcttta ggggctacat tacggtttga cgaggacttg
     4261 gtttctggct tagcgacatt cttatccttt tcaggatcct ttggctcctt gcctaagggc
     4321 tttgtgtctt tagaatggcg ctcagactcg ctgagtttat tatcggttct gatttgagct
     4381 ttggttaaaa agccgctgac atcactaccg gtagaggctt ttttaggtat cttgaccccg
     4441 ttgataacaa tctcataaaa cataccgtcc atgagctgat tcacaaaggt tgccttacct
     4501 gattgatcag ttttgcctat tgccctgata gctccgtatc gatttttcag cacaacctct
     4561 tgccctgcca acttatttcc attggcatca taaacagtta ctatggctgg tgtcttagag
     4621 taaacaacag gctttgttcc tttaccgtcg acataaaaag cagcagcctt atgctcatta
     4681 gactcactcg tgcgaacagt atagccctgt agcttaccat caattgagac actgatatta
     4741 cgtgatagtg gtagtttggt aaagactgct tgaccatcag catttgtctt tgctgaagca
     4801 attgtcgtct tagcaccgtc tatcagagca gtcaagctta cctccttgcc tgcaacaacc
     4861 ctatcctctt tatctagggc agtgacaaca aaatgaaagc cttcctctag cggacttgac
     4921 tttccatcct cctgcttagg agtgtccttg gactgaggtg acgtacctga tgacgagctt
     4981 gatgaggtat caaggtaagc attaacagac atttttgtca tgacctgccc tatatactta
     5041 ccattaagct cataatgata aaaggttccg tccaacaaac gatccttgaa ggttaccttt
     5101 ccatttttat ctgagacaag acttcccacc agttgaccct gacgtatttt tagggtgact
     5161 gtttgccctt ctaagggctc actatcttga tttcggaccg taatatcaat gacattttta
     5221 ctataaagag gctcctttgt ccctgctccc ttagcgacaa agcttgctgc ctctttagat
     5281 ccagcaagac tggttctcac tgtatagccc ttggtttccc cgtcaacaga aacactcaaa
     5341 ttaatgttta agggtaattg agtaaaaata gcctgaccat tgctgttaga gacagcagaa
     5401 gctacctgct tagcgggatt agctgtcgtg tctaacaaga caactgtttt tccttcaaga
     5461 gcacgaccgt tgctatcaag tatcgtggca acaaaatcaa aaccctcagc cgcttgcgac
     5521 gtcgcagtga caacgttgtc tctggcataa gtcgtatagg tattggcatt ggctgccaag
     5581 gccaagctag atataacagt aaccgttaaa agactgactt ttttcaatga ctgtttcttc
     5641 ataaaaaagc tcctttattt tgattaacta gcctagtttt aatgggaaat atccccttga
     5701 taccctttct gaggtgatag gaacagcagc aatctctctt agcctatgat gcctaagctt
     5761 taaagctaag ttttcaaagt ccacctaagg ggctacatgc cacaacaaaa agcatcagat
     5821 gaacagacat ctagaggcaa cagccgatct aagataatag ttagtagcca ttttagctac
     5881 tctcaaggct gtcgccgcag tgatgatgtg attgtctatg ctttttaata aaacttaact
     5941 agttaagatt tttgtgctgc tatcctatca aataaccccc gccaagtcaa caacaatgct
     6001 cataccacag caagcaaagc attttgatga tgactgaaca gccaaatcag ccaagcccca
     6061 ggcagcaaaa aagaggattc aaaccaaatc ctctctctac taagcctgct gctgttaacg
     6121 tatcatgcta aaggcaaatg gtatagccac gctgatatga aggtctgatt aacagctacg
     6181 acggacacgc ttgttaaggc taccattgct aatcacacta ggtcatatcc tccaccgtat
     6241 aagaatgact aacttcatta ttcagattaa cgatatacct gcaggtgctg aggaagtacc
     6301 ttgacagtga ttggtaaggc ctcaccctca tcaccgtcca cattgataga tagctgtcct
     6361 tccttcatgg caatagtggc ctccttgaag gtttgatagc caagtgtttg atctgaagcc
     6421 tcaactccct tcaataggct aggaagggcc ttcaccgttt ctaatagatt gctatccttc
     6481 agatagataa ggtgcagcaa accatcgtcc acacgtgcct ctggcaaaat ccgctcaaag
     6541 cccccgattg aattggtcaa gccaatcaag agtgttgtgc tgttgatttc ttttgttttg
     6601 ccatcaatat ctagctggaa ggtatagctt ttatttttga tcagctgctt aaagcctgac
     6661 ataaaataag ccattttccc aaaggtcgtc ttctcctcag gggcaacatc attgatcgcc
     6721 tctgggagcg tccctatggc aacaacattc ataaagtaag catcgttgac cttaccaata
     6781 tccagaggac tggttgtctc aaagcttatc tgattaatcg cttcctctgg gtctaacgac
     6841 atgcccaagg cacgtgccaa atcattgact gttcctagag gaaaaaagcc aaacttaggg
     6901 cgatagtcct gctctgcaag cccgctgatc ccttcattga ctgttccatc acctcccatg
     6961 acaaagacac tgtccagccg ctgctgggct gcctcatgag caaaccgttt ggcatctcct
     7021 cctttttcag tgtgcttaac gtcaacatca tcaaaatacg aagctagttt atcataggct
     7081 aaggcttcat attccttggc tttctcacca cctgagctag ggttaacaat caatagggct
     7141 tttttcattt atgatatcct acattttcta ttatatttca cgactattat aatcattatt
     7201 caaaacatcg tcaaataata ctcactatgt cattagtcag tcttaaagct tctaatatgg
     7261 ttgccgtcta gtgtttcatt ttactgaact ctttacccag ctagctcaat gcctaaccaa
     7321 tcgtgctgtc tcttaaggtc aactctgtcg ccaatatcgt catggtcttg acacgttctg
     7381 ggttaaggat attcctatta agcacatcaa cagccatacg tcccatatcc tctgtaaata
     7441 cagtcacact agaaagcgca ggaaagacct gtcttgttaa aggagtatcg ttaaaggaga
     7501 taagctcaac acgctcaggc accgcaagcc ctctttcttg gagagctctt agagcaccta
     7561 ttgcaagggt atcattagca ataaaaaatg ctttaggcaa atcatcacct agctcctcaa
     7621 ttgcctgtgt cataagctca tagccagatt gtgctgaaaa aggaccgata tagacatacc
     7681 tcggctgata aatcccatgc tcagaggcat aatttttata ggtgcgaaag cgctggtcca
     7741 ctaaagcttc tctaccgtca gttgtctttt cctcaccagc aatcatgcca atgctataaa
     7801 tccctttgct cataaaataa tcaagaactt tcagcactgc attgtcaaag tcagttgtga
     7861 cacaggggtg gcccaattca agcgtgtcac tatcaacaaa caccaaatgc tgggataagg
     7921 cttcaagctc cttgatttga caagcgctaa actttccaat agcaataatc ccggcatggt
     7981 catctgaaac cctcaaaatg tcattgttga aataacgaac aatatcataa tccaattcat
     8041 aagctctttt ttcaatgcca atgcggatcg cataatagta gaggtcattg agctcctctt
     8101 cttgagaata ccattgaaca atagctattt ttagctttga tttagggcta ttcgtcgctt
     8161 ttaaatgctt ttggtagccc agctcatcag caattgtgag aatgcggtgc tttgtctctt
     8221 gaccaacaga caagctttgg tccttattta aaactctaga aacagttgca ggagaaacct
     8281 ttgccagagc tgcaatatcc ttaagcgtta ccatatcaaa ccttctttct gatttcttct
     8341 agtatatcac aagcattttc aaaagcaata tttagtaaaa ttttagtaaa aatgttgacg
     8401 agcagcttag cgaagcgtaa aatcaagcta tcaacatcgt taaaggagcc gctaatggat
     8461 atcgcgcaac ttaagcaaag ctttactgac gtttttggca aggagccaga tgctgtcttt
     8521 ttctcaccgg gtcgcatcaa cctcattggt gagcacactg attacaatgg tggacatgtc
     8581 tttccagctg ctatcagtct gggaacctat gggctggccc gcaagcgtga ggatcagcag
     8641 ctgcgctttt tctcagcaaa ttttgaagag gctgggatta ttgaggttga cttaaatcag
     8701 ctgacctttg atcaggctga cctttgggct aattacccta agggagttct ctcctttttg
     8761 caaaaagctg ggcaccttat tgatacgggc tttgagcttt acgtttttgg caacattcca
     8821 aatgggtctg gtctgtcctc ctcggcatca ctggagcttt tgacaggtat tgtggcacaa
     8881 gagctgtttg ggcttgatgt ggaacggtta gatctgatta aaatcggtca gcaagctgaa
     8941 aatcacttta tcggggtgaa ttcaggtatc atggaccaat ttgccatagg catgggagct
     9001 gataagcagg ctctatacct tgataccaac accttagcct atgaggctgt tccgcttgac
     9061 cttggtgatc acgtgattgt catcatgaat accaacaagc gccgagagct agccgattca
     9121 aagtataatg aacgccgagc agagtgtgaa caagcccttg aggaattaaa tgcccttctg
     9181 gatattaaag cactggggga attagacgct cagcgctttg atgagtacag ctaccttatc
     9241 aaagatggta aacgtctcaa acgcgctcgc cacgctgttt tggaaaatca acgaacactc
     9301 caagcaagac aggcccttga agcaggagca ttggagcaat ttggtcgtct gatgaatgct
     9361 tctcatgtat ccttggagca tgattatgag gtcacaggcc ctgagctgga cacactggtc
     9421 cacaccgctt gggagcaaga aggggtccta ggggctcgca tgacaggagc aggctttgga
     9481 ggctgtggca ttgctatcgt ggctaaggat aaggtagata gctttatcga aacagttggc
     9541 aaggcctata ctaaggtcat tggctatgct ccagcctttt atctggctga gattgctcag
     9601 ggagcacgac tactttcaag gaaataagat atggcaagct taatagacac ctttgtaagg
     9661 aaggtgattg aacacagcga ctacacatca gaggacgcta tttatatccg caatcgggtt
     9721 ttagcattgg ttggtgagaa ccatgtctgg caagaaacct ccttaacagc cttaatagct
     9781 ctcaaagaag cattggttga gctagctgct gaaaatggca aaataggcag gcttcctgaa
     9841 gaaaaggact gcttaggagc tgaattaatg aacatgataa cccctattcc aagtgtggtt
     9901 aatcgtcgct tctgggatac ctatgcacaa tctcctcaac aggctatctc agatttttac
     9961 cagcttagtc agctaaatga ctacatcaaa acagcagcaa ttgccaaaaa catctccttt
    10021 acagtgcctt ctcaatatgg tgatatggct attaccatta acctatcaaa gcctgaaaag
    10081 gaccctaagg ccattgcagc cgctaagaag gctaaggcat cctcttatcc aaaatgccag
    10141 ctttgtatgg aaaacgaagg ttatcaagga cggattaacc acccagcccg agctaatcat
    10201 cgcattatcc gtatgagctt aggcaatgag gcttggggat tccagtattc accctacgct
    10261 tattttaatg agcacagtat tatttttaat actgagcatg tgccaatgac aatcagtaca
    10321 agcaccttta gacagctcct tgatattgtt gatatcctgc cagactattt tgtcggctct
    10381 aatgctgatc tgcctattgt tggcggctct attttgaccc acaaccatta tcaggccggt
    10441 cggcacgttt ttccgatgga aatcgcaaaa caagacaaac gctttacctt taaaggattt
    10501 ccagacatac aggctgccac tctcaactgg cctatgtcag ttatccgact gcgcagcagc
    10561 aacaaagatc agctagttca attagcagac acgattcgac tggcttggcg tcattattct
    10621 gacgacagtg ttgatatcgt cgcttatacc aaccaagagc ctcaccatac catcacacct
    10681 attgccagaa aaaaagaagg gcagtttgaa ttagacttgg ttctacgtga taaccatacc
    10741 tctgagcaat ttccagacgg tgtttaccac ccacatgccg atgtgcaaca cattaagaaa
    10801 gaaaacatcg gccttattga ggttatgggg ctagctattt taccaccgcg cctcaaagag
    10861 gaattggttg aggtcaaaaa atatatcctc aatcaagcca atcaaatcgc agactaccac
    10921 aaggactggg ctgatcagat cacattacga ccagatctct cagcgataac tgttgatgac
    10981 attatccaag aagaggtcgg ctctgtcttt gttcgtgtcc ttgaggacgc tggcgtctac
    11041 aaacgtgatc aagaaggtca agcagccttt atgcgttttc ttaagagcat tggcattgaa
    11101 gcaattgaag aataggagga aaaaatgact gttctagttt taggcggtgc aggctacatt
    11161 ggatcacata cagtggactg gctaatatca cagagagaag aaaaagtcat tgttgttgat
    11221 agcttggtga cagggcaccg taaagccgtt cacccagagg ctctgtttta caaaggagac
    11281 ttagcagaca aagcctttat gcgtcaagtc tttagggaca atccagacat agacactgtg
    11341 attcactttg ctgcctcttc cttggtcgca gaatcaatgg cagaccctct gaaatacttt
    11401 gacaataaca cagcaggtat gattaagctg cttgaggtca tgagagaagc caaggttaag
    11461 cgcattgtct tttcatcaac agcagccgtc tatggcattc caaaaacagt ccccatctta
    11521 gagtcagcgc ctaaatgccc aatcaatcct tatggccaaa gcaagcttat gatggaaacg
    11581 ataatgacct gggccgacaa agcctatggc atcacatttg tggcccttcg ctacttcaat
    11641 gttgccggag caaagccaga tggctccatc ggtgaagacc acgagccaga aacacattta
    11701 ttacccatta tcctacagac tgcacaggga gtgcgtgagc aggtgatgat ttttggtgat
    11761 gattatgaca caccagatgg tactaacgtt cgagattacg tccatcctat cgatttagct
    11821 gatgcacaca ttttagcgat ggcatacctg cgtcagggca aaccatcaca ggtctttaat
    11881 ctagggtctc aaacaggctt ttccaatcgt caactgcttg aagccgctcg tcgggtaaca
    11941 ggacaagcca taccagccaa aaaagctgca agacgtcccg gtgatccaga caccttaatt
    12001 gcgtcatcag aaaaagcacg caaggttctc aattggaagc caagctatga cgatattgac
    12061 aagataatcg catcagcctg ggcctggcat accaagcatc caaaaggata tgacgataaa
    12121 gcaagtggca gctagtccct caagacagct accacagcaa gtagtcagcc tcccttaatt
    12181 catacaccta tactaatagg agaaacaaac tgtgaacatt tatcaagaca tcattgaata
    12241 catcgatcaa gtgccagtca cccagctaag actgattaat actaacggtg ttgaggctca
    12301 cctattgaca ctaggagcca ctctacaggc ctttctagtg tcaaatgaaa agcagccaaa
    12361 aaatatcatt ttgggacatg accgaccaag tgactaccta aaaaatcctc tttgtgcagg
    12421 gcaaaccatt ggccgagtag caggtcgcat aaagagagga agctttcagc tagagcagca
    12481 aagggtttgt gttgacacca atgaaaatgg gcattgcctg catggaggct tcaagggctt
    12541 tcataagctt cattggcctt atgatacccg ccaaacagtt gattaccttg aagtaacctt
    12601 taaaagggat attttagaag cagatgacca tttcccaggt gacctgaccg taagcattac
    12661 ctaccgtcta gacaaccata atcgtttaag cattcacttt aaggctcata gcatgagagg
    12721 cactagccta ttcaatccaa ccaaccatgt ttattttaat ttagggcaaa cacaagactt
    12781 aaccaatcac aacctataca tcgcagcatc acataggatt gaaacagata atgagctaat
    12841 cccaacaggt caaaagctag cagttgacca gacggtctat gattttagat caataaagtc
    12901 cctctatcct gctattgtcg aaaataatgg ctttgatact gcctttgaaa ttgatcagca
    12961 ggctattgga acaaccaaac ctattgctgt cttacaagac agcgtcagcc atgaccaaat
    13021 cagcatctac tctgaccgaa acgcactcgt catttatacc atggacagta tccaagatgg
    13081 cttgtatttt ggaagagatc agggcaagga gggactggct cgtgagggga tcgctatgga
    13141 agcacaaacc ctgcctgatg ctattcacca caaccagttt ggtgacatta tcctcaaaga
    13201 aggaggcacc aaaagctaca ctatctgcct agcctatgag catctgccag attaacataa
    13261 gtacagccaa gctttaatga aataacaaga ccttgatttt tttgaattgc accccaaccg
    13321 ttagccaaaa actctaacaa gcgaggatca gttcattcat caaggtcttt tcctcttttt
    13381 atctataggc gttacaaagt agatatagga acatcatacc aaatatgtgg aatgctaaga
    13441 gcttatcatc acaaagcgaa tacatgttcc gactacatct atgcattagt aagtcttttt
    13501 cctaaacgaa gtgttgccag ctttatgaga tacttaaaag tataagagca gcctaatcat
    13561 ttttgacaaa gacaccaacc ttaagcataa acataggcat cagaaatttt ggtatatggg
    13621 ctattatgga gacacagctg gtaaaaatct aaaaacgata gccaaatata tttcaaatca
    13681 ctataggaag atagggtagc aaaccaactg acatcatttg agaccattga tccatttaca
    13741 ggccaaccaa ataagaaaaa gtaacctttt gattgaactc ccgctcggaa aagtggagcg
    13801 cgagtattca atgacctcgt tatcctcgac cgatgagagc agcttatagt cacagtataa
    13861 agaggctgga acagacaacc tcttttgatt gacaataagt gtttgatagc attgtatggg
    13921 attactttca catcattcag cacctgggtc gagctttgat gaccgccaga attgatagcc
    13981 attatgaagg gctttgagca gccatttctg ctttatcgaa ccataaaata tcattgatga
    14041 ctgctccaaa aggacagtca taaactgtct gatcagcgct tctagtcacg aacctttaag
    14101 caaaccttaa tactcaaaaa aggtaagtca gaaaatactt gatttctcag atgagctgtg
    14161 gaattaccac gacctttacc agctcttgct ctttcatttt caaaaagtgg gtaaccgagt
    14221 ttttcgggct gattgaagag ctttaagctt ggtcaatcat cacgttttaa ccgtcctcaa
    14281 aatctttttg aaatacaaac cctacatcac aaatgcctta ttccaatgct aaattggagc
    14341 ccactaacaa gactattaag gacatgaaag agcaagcctt tggatttagg aactttaaga
    14401 acttcaaagt caagattccc aatgctttaa acatcacaaa agaagagaca aaatttatct
    14461 cttctcgtgc ttagctatca gtcacccact gcagttgaca ttgagccaaa ttatagagcc
    14521 attttcgtag aaagcacaga aaaaacaccc atgaggtaaa ctcttgagtg ctttgaaacg
    14581 ttgatataat gcgatatatt aacgttttga ggcacggaga ctgcgtctcc tttgcagccg
    14641 tattcgtaag cgactaaagc cgcaacgact acgtcaattg cgtcgccagt tctttcaaaa
    14701 aagaaaatac cccatggtaa cccatgaagt attgttctgc tgtattgtag ctggttctta
    14761 acgttttgag aactgactag ctttacgagc tttcttaaga cctggttttg ggtgacaaaa
    14821 accaaatatc tgtaaaagct tatcaaatca agctttcaaa actcattttc attaaatata
    14881 agcactttta acccaatcct acaaataata gattaccatt agattaccaa aactcagttt
    14941 tcggagctta tgtagttgag aaaatctcgt atttactttg cttttatata tccactttat
    15001 actatcatcc cgtcataaca gagcatgatt aaatagttac ataaaaaaca atacttactc
    15061 tatcattaaa ggatattgtt aaaaagattc tctaaatcat ttaaataatc agttttagta
    15121 cttctaatac gaagaatatc tacccttgac tgacgaatta aataaaatac tatgaaatgc
    15181 ttactaggaa tcatccttag ctggccttca ggaaatagtt tacgtcctac acgatcgtca
    15241 aaatcaacat aaccttcagg ggatatctca agaatagaaa tagctgactg caaagattca
    15301 ataacttttt gagcgcttga gtgcgaaaat tctgttaaat agtagttata gatttcatct
    15361 aaatcttgtt ctgccttatt tgaaatatag atatcataag ccatattttg aaaatacctc
    15421 attagctggc ttcgtacgtc ctgctaaaat atcttgatac ccttcatcaa gctctgatat
    15481 cagttcattt aaaaatgatt cagctctaat ttgttctgca gttttaatag gtaaatcttt
    15541 ttcttccacc acccgttcaa caaatagatt aagagcatct ggaacactaa tatttttagc
    15601 ttctaaaata cgctttgctt cttccatcat ttccgtattt actctaaaat tatactgtct
    15661 atctcttatt aatgtagcca ttatagtctc cttaattgcg ttatccttat gtataacaag
    15721 attataacaa atcaatagtg acttagcaat ataaagcaat ttgcaaactt gccattagtt
    15781 tactaaaaat aagtatgttt tcggaattta tcagttg
//
LOCUS       DARYXZ010000049        15637 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYXZ010000049 DARYXZ010000000
VERSION     DARYXZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15637
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1031)
                     /locus_tag="TV186_001597"
     CDS             complement(<1..1031)
                     /locus_tag="TV186_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1532975.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
     gene            complement(1037..1891)
                     /locus_tag="TV186_001598"
     CDS             complement(1037..1891)
                     /locus_tag="TV186_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1532976.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            complement(1958..2158)
                     /locus_tag="TV186_001599"
     CDS             complement(1958..2158)
                     /locus_tag="TV186_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1532977.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            complement(2531..3268)
                     /locus_tag="TV186_001600"
     CDS             complement(2531..3268)
                     /locus_tag="TV186_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1532978.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            complement(4019..4324)
                     /locus_tag="TV186_001601"
     CDS             complement(4019..4324)
                     /locus_tag="TV186_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1532979.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            complement(4326..4664)
                     /locus_tag="TV186_001602"
     CDS             complement(4326..4664)
                     /locus_tag="TV186_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL1532980.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSPGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            complement(4692..5447)
                     /locus_tag="TV186_001603"
     CDS             complement(4692..5447)
                     /locus_tag="TV186_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL1532981.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            5708..6163
                     /locus_tag="TV186_001604"
     CDS             5708..6163
                     /locus_tag="TV186_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL1532982.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            6147..6797
                     /locus_tag="TV186_001605"
     CDS             6147..6797
                     /locus_tag="TV186_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL1532983.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            6907..7811
                     /locus_tag="TV186_001606"
                     /pseudo
     CDS             6907..7811
                     /locus_tag="TV186_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(8164..8439)
                     /locus_tag="TV186_001607"
     CDS             complement(8164..8439)
                     /locus_tag="TV186_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532984.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(8862..10412)
                     /locus_tag="TV186_001608"
     CDS             complement(8862..10412)
                     /locus_tag="TV186_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1532985.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(11083..11643)
                     /locus_tag="TV186_001609"
     CDS             complement(11083..11643)
                     /locus_tag="TV186_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1532986.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(11621..12490)
                     /locus_tag="TV186_001610"
     CDS             complement(11621..12490)
                     /locus_tag="TV186_001610"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL1532987.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            12582..13853
                     /locus_tag="TV186_001611"
     CDS             12582..13853
                     /locus_tag="TV186_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL1532988.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(13889..14227)
                     /locus_tag="TV186_001612"
     CDS             complement(13889..14227)
                     /locus_tag="TV186_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1532989.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(14327..15415)
                     /locus_tag="TV186_001613"
     CDS             complement(14327..15415)
                     /locus_tag="TV186_001613"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL1532990.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         4830 a         3442 c         2720 g         4645 t
ORIGIN      
        1 gccaatttta ataataattc ttgtgtacca aaggtttgta cggatacaaa tgttaacagt
       61 ttgttcatca aaccttctgg aaaaattccc attagaaaga ccggtgcata tacaataaga
      121 gcagatatac caaaagtggt tagaggagac ttagttagag atgaaactag tgcatgaatg
      181 cctgtcataa atatcaggcc aatatactga aacaccaata aatagacaaa cgcaatgcct
      241 aaggtcatct tttccgggaa agccataatg tttatcactg gatcaatcca atacaaattg
      301 agttgtaagc tagtgtccca gccgctaaaa ccaaaatagg tcgcaaagac agcaaagacc
      361 agaccactag caattgcaaa taccaaagta ctgacagcta tgctaactgc taatttagca
      421 agagtcaatt taccacgtcc aaaaacagtc gtcaataaga tagagttcat ctttttagat
      481 gattcccctg aaaataaagg agccgttata taaagacaaa gcataacaac aagaagataa
      541 gtactattgg ttacatcaaa caactgattc caaggagcaa aattacctaa cttcaactct
      601 ttcaaaggca gagcggaccc caactcttca cgtgatttga gatgaacatt gtcaaatgtc
      661 agagacttat cagtgctatt aatagcgata agcttatcag tagacttagg cactaaatga
      721 gagatagcat aatgtgatac cacactatat acacccttct tttttaggtc tgattgattt
      781 ttagcataat cattgaggat acgactaatc agatcgtcag ataaataacc tgtatgcttc
      841 tcagcaattt gttggttaat tgctacagct gcacgtccat gaacctgatc tgcagaagag
      901 ccactgatct gaccgttaaa aaaatgctgg taaaaaagac cacctacagc caataagacc
      961 actacaatcg caccaaatac cgactgtcgt cttaataatt ttttaaactc aaagggtatg
     1021 agagatgcca tagaattcac tcctttctaa aatgataaat gtagagatcc tctaatgttg
     1081 gtgacacagg atttgcctga taacaaggac tctcatcgct cacaacacgt aagatacgat
     1141 tattttttac aattttttca ttgacaacgg catagtcagt caaaaatgct ggtgcactct
     1201 ctgtagcaac aggaatctcc cataccttgc cgatcattgt ttgaactaac tgatcaacac
     1261 ttcctttttc tataaactga ccatgcttta gaaggattac ctcctttgca accgcttcta
     1321 catcagatac aatatgtgtt gataggataa taattttttg ctctgataaa tcactgataa
     1381 tatttctaaa ttttacacgt tcctttggat caagtccgac tgttggttca tctaaaatta
     1441 acagtaaagg atcgttgata agtgcctgag caatacccaa tcgctgcttc ataccgccag
     1501 aataagaagc aattttcttt tttctaacat cataaagacc taccagcttt aataaccgat
     1561 cagcttctac taaagccttt ttacgtttaa cattcttcaa agcagccata taaagaagga
     1621 attctaaacc ggaaaactgc tgataataat taaactgttg aggtaaaaag ccaatattct
     1681 ggtaaaagtt ttttggttgt tgttgatgat ttaaactaat ttctccacta tcaggaactg
     1741 taaactgact aatgatgttt aataaagtcg ttttaccggt cccatttgct cccaataacc
     1801 catacaagcc tggtgtaaat tgtgcagaaa tacgactcaa caccttttta cttccataag
     1861 atttagaaat attatctagt attaacaaca ttgtcattcc tcctaagtaa aaacccaggg
     1921 aacagcacca cttcgctgct ccccagatga ttaaccatta agcattatat actcgacaaa
     1981 cggtaccagg ataaagaatc atgtggttat cagcattttc ttgtgctgta tctcttaata
     2041 gatgccatgc acttgtataa ccatcagtgc atctccacct ataaccccaa ccaccttcaa
     2101 cgcctgcaag catatcagca gtcattgtac taaattgttc aattgttttt gtattcatat
     2161 cgaatacctc cttataatga ttttatctag ctacagtctc gacaaactta gtgtagcgct
     2221 ttttaaagca acgacactca aaaatcttga atggttctta ttttgtcgtg aatggtcaat
     2281 ttttcttctg aaattaccag ttaagatcat atggatacct ttcacgagct atatcttttt
     2341 ctctcttttc ttatgatata attgattttt gcatgtacat catatctctg agcatcatta
     2401 gaaaccaact gttacccctt tttcttagtt ttgactaaat atatttataa taaatatccc
     2461 ttaaggtaaa tggtatcaac gaggttgatt aaaaaacaaa tgatggcttc cacatggcat
     2521 tcttttactg tcaatgcaaa gccttaatag acgcctcaag tgctttcatt tttagtcttg
     2581 aaaccatgca agactgccca ttcttgaaat agagtaaacg cttatcacga tcaagaaacg
     2641 aaacattgta aggattgata acataagaac gatgacattg gactagtctg gaatcttgct
     2701 taagaacctc tgaaagaaag ccataaaatt ctattcgctc gttttgagaa tgcaaaatca
     2761 acttgtgagg agtactagag gtctcaatga acaataggct tgaaaaagga acctgcacct
     2821 gagccttagc cgttgcaaaa ataaataagc cctctgaggt tacattttct tgctcttcat
     2881 aagcatatat aatggctctt tcaatcctat ctgagaaatg tttcattgac aattccttat
     2941 cgataaaatc tagagcagac acctgataac gaaaagaaac tggcataagc tcagaatgtg
     3001 tggtgacaaa aacaatgagg gcataagggt cacgctttct gatctcacga gcaacagcta
     3061 agcccttttt ctcatcattt cgaatttgaa tatcgagaaa gaaaagctga tgcctgcctc
     3121 tctctgtaac atttgccaga agctggtagg gctttccata aacttcaaaa cgatcacaag
     3181 tccagtgatg cttatccaat atctcttgaa tcttcatctc aagcctaaac tgttggccta
     3241 gatcatcttc gagaataaaa atattcattt agaacctcct tattgcttta gcttatcgtt
     3301 tttttaggag actaaagcag ctttttgaac aagtgatagc tagaacgctc tccttcatga
     3361 acagtatctt tttagcatca ccattaaaac catgaccgtt aagcttatta actaaaggtt
     3421 gtcaatgact tctaaccaac ttgtcattgc agcgttttca ataggcctta gcgaatcacg
     3481 cgcctcaaac aattttttta ccacagataa tatactagca cgagccgcaa gtcatacctc
     3541 tttgagagag agctcttaac gactatcact tttgtttgac aagtcatcag ctatcaatcc
     3601 acacactgat ctccttgcac agacattcta acacaaagct agggagcagg gagttaaaat
     3661 cttaaatggt actgattatg tcttaaatgg taaataagga aaactaacaa tggctagtca
     3721 ggttactgag gctatctgat gattagctgc ttgtagctat accttctcca agcaataagt
     3781 ttctagaatt attggtaaca aatacattag gtatccggga tattctgtca tttattttat
     3841 cataaaaaca atctttttat catcaaaaca ggtaattgtt attattatta atcactttga
     3901 gtgatttgaa gtaagctaga tcttcagcta aaccttatga cactaaacac aaaaagcccc
     3961 ctaaggcagc taaaacacca gcctaggggg caagattcaa gagagtcact ctatactttt
     4021 agaccatttc aatttgcagg tatttacaat ttgttgcagc ctctaaatga taaaactgat
     4081 gagcagagat actgatcaat ccgcctgctt tcatgtcatg agcctgatcc gtaagactaa
     4141 ccagcaacct tccttctaag acaagcagga gcttaccttc agggcttgat tcgttactaa
     4201 tcgtctctcc ctgatacatg gcatataaaa caacagattg cttaaagcct aggctttgat
     4261 gaagcgaacg actagctatt tggtcatcat gataccttac taattctaat aaatcagcca
     4321 acatgctaag cctccggctt tacaacaact aaaagcatct ggaaggcttc cttagcaaat
     4381 aagctatgag gaatattagc aggcatgatg atcgtctcgc cagcagctac ctcataacag
     4441 gcttctccaa tagtaatgtc aactactcca cttaacacgt taaccattgc atctcccggt
     4501 gatgaatgac gaccgatttc ttgtccttta tctaatgaaa acagggttat gcccaaatct
     4561 tttctttgaa ctagtgttcg acttaatatt tgatcctctt caattggcac ttctgccttt
     4621 aaatcaatga ctgtgcttgt tggaatttta cgaatcaatg acatgtcact tctcctttac
     4681 cattattcta gttatttttg acttacagcg gcaatataac acagctttct tccagttttg
     4741 ttgaagaaat gacgcatctt taaaaactgc tttcgatttt cttttttcat gccgcgcagc
     4801 ataatacgaa tcgcagcgac aaccccttca tctttaatca tgccaagcgg ggacatgagc
     4861 gtcatattac cataggagta attgactgct gtgaagccac tctttaccag caattgtctc
     4921 caggcatcta actgcaatgg cgatacgttc acattaatcg tatctcttag ttgctctata
     4981 atagcctttg tttcatcagc ttcataggaa acatcatgcg ttagtaggcg accacccggc
     5041 tttaaaacac gccaatattc cttaagtgct ttttcctttg cagcatcatt caacatggtt
     5101 agcatagctt cgttaataac gatatcaaag ctattatctg caaaaggcag cttcaaggca
     5161 ttagcttggg taaggtgaat atagtcttgc atttgtgctg cctcaatagc ctttcttgcc
     5221 tccgccagta ccttggtatc caaatctact gctgtaatat gacactgata agtctgcgcc
     5281 agctcaatgg aggtcgtgca acggttgcag gccacttcca agaccttgca atcactcgaa
     5341 aactctcctt gctgaaccag ccaattcgtc gcctcaacac cgccaggccg tagtcgtttc
     5401 tttcccagtc gagctaaaaa ctggtgacca acttcttttt gagacatcac atgccctcct
     5461 atttgctctg ctatatatca tcacttagaa taaactaact gttaacaaat tgatcaataa
     5521 atgattacta caactatatc acacttaaag catatcctca atgaagctta agcatttctg
     5581 atgattgttt ttatgataaa tcatagaatt ggctcatatt tcttgtgcta tacgaccttt
     5641 tgacttgcta ttatttttta aataatatat aatctagtta tcaaaactag ataaagaggt
     5701 tttagtaatg gaatatgata agctgcccag ctggaaggat ttacctgatt tggagttata
     5761 cttagatcaa gtgttactct atgtcaatca ggtcacacaa ttgagtcaag ccacagacca
     5821 taagctactg actgcttcaa tgatcaataa ctatgtcaaa catggctata ttgataaacc
     5881 tattaagaaa aaatatcaaa aaaagcaggt tgcccgctta attgctatta gcattttgaa
     5941 aaatgtattt cctattcaag atattagtca ggtcttgacg agcctacaag cagcctccag
     6001 ctcagaggtc ttgtacgata cctttgtcaa ctattggaat aatggcctta cccaatcaac
     6061 gcctgaaatt attagctatg cttgtcaaac cgtcaaggac tatcagcaca caatgaagct
     6121 ttcaagagaa atggaggata ccaagcatga accaaacctt taaacaaagt ctcccactat
     6181 cagttaatga agaggtcgca aatagtgtga cacacgctat tggagcagct gctatgctga
     6241 tactgctacc catcactgct atttactctt accagactta tgatctcaag gctgccgttg
     6301 gagcatctat ttttatcatc agcttatttc tcatgttttt atcatcaacg atttaccatt
     6361 ccatgtccta tggaacaact cacaaataca ttttacgtat cattgatcat agcatgattt
     6421 atattgctat tgctggtagc tatacacctg ttgccttatc cttggttgag ggcttgttgg
     6481 gctatgtgat tatcatactc cagtggggaa tcacactttt tgggattttg tataaaattt
     6541 ttgctaaaac gattaatgaa aagttcagtc ttgcgcttta cattattatg ggctggttgg
     6601 tcgtttttat cctgccggtg attatccaaa aggccagtct gccatttgga atcttgatgc
     6661 tactaggtgg cttatcctat actgtcggcg caggctttta tgctaaaaag aagccctatt
     6721 atcacatgat ctggcacctt tttatccttt tagcctctgc tttacaggtt attgccatta
     6781 ttttctatat gctgtaaaaa gtagctgttg ctacttttta aacgcgagcg cttgcttacc
     6841 cccagacacc tggcttgatt catgctataa taaagggcag taaatagttg aagggatcaa
     6901 agcaatatga aaacggtaca tattttttac aatcctaatt caggaaaacc agaaaatgac
     6961 ctggctgaaa aggtcaagca ttatctgatt caaaatggtt tttctgaaga caaggttcag
     7021 attattaccc ccaaaaatgc tgatcaagcc tttcaattag ccaaaaaatc ctcacaggat
     7081 catattgatc tagtcattcc tctaggcgga gatgggacac ttaataaaat tattggaggt
     7141 gtttatgaag gtggtgctca ttctgttatt ggactcgtac cgtcgggcac tgtcaataac
     7201 tttgcaaagg ccttaaacat tccactccag ctaactgagg cacttgagac gattttatct
     7261 ggcacgatta aaaaagtaga tatttgcaag gtaaacaagg gctatatgat ttctagccta
     7321 accttgggtc tgcttgctga tattgcggct aatgtgacta cagaagaaaa acgaaaattt
     7381 ggcccttggc ctttttaaag gatagtatta agatactaaa acgaaaccgc acatatgcaa
     7441 ttagcttaat tagccatcat catgttcttc acttgaaaac caaattctta ttgattacca
     7501 caaccaatac tatagcaggt cttccatcgt tttcaccagg tgcacaagct gacgatggct
     7561 tgtgtcaagt ttacacgatg agccagctat catttctgaa atgcttgcgc catattagag
     7621 actttagacg gggggatttt tccaaggtaa aggagattag ccattttcaa gctgattctc
     7681 taaagctatt gccacaatat cagcgtcaat cagccattcc tagaactcgc attgatggcg
     7741 ataaggctga tgatctccct gttgaattga aggttattcc aaaagcgatt tccattattg
     7801 ttagccagta aaaaagtgcc ctagggcact ttttgatata gattcatctc caagctgagt
     7861 tttagaaaac taagctatag ctataacgtt agctgtggct tcttcttgct ggcttgcagt
     7921 actcttttct tgtcttaaca gctagctctt tcataatatc ggctttaaca aagaagctat
     7981 ctgactagtc cgatcttcta ttctcaggac aaacagcgag aaaggggatt ttctttgaat
     8041 cctagagaac cttagctatc tctgtgtctc attgtaagtg cagctctatt gactgatgcc
     8101 agctatagca ataagcccag tcgcatatta taaaggatta tcaggcgatt tagcttgaca
     8161 ctcttatatc tttattgctt cttctaaggt tcctttaata gctttagctg ctgaatgacc
     8221 acaggcatta gcagcaacct tagaggcttc taccttatca gaggctgtct caataagttg
     8281 tccacccttt tcttggatat aatggttcaa ctcctcaata gtttcagagc cttcctttaa
     8341 gagctctttc tttttggctg aggataagct taaatatgtc acagcaattg ctgctgaacc
     8401 aagaagtaat cctaagccga ttccatagct ttttttcatc atcaacccta ctttctatga
     8461 ccttccttaa tcatcttttt agctaatttt acagctggta ctactaaaag caccaattgt
     8521 aaaagatcca tatacttgat ttttcgtcgt tttttcacca tgtgctattt cctttttctt
     8581 gtttgcacca tacaatcgtc ttttattgcg cagtgccaga gactgcctga ttaggcagcg
     8641 taagctaaga actatcagcg tgtcagacta gtctagatac agctaagcac tagcttgatt
     8701 acgataatac ttaccgctag gccataagct cagctatcat caaatctaaa gtgacaacgc
     8761 tttttattta ttatattgtc attttactaa aatacacaat tatcgtcaat gcttttgctt
     8821 taggcagcaa aaatgcccaa gataaagacc ttggacatct gctacaatga cgttaattga
     8881 ttgaaatccc aaatatcagt tacccagccc tcataaaact ccggctcatg gcaaaccatc
     8941 aaaatagagc ctttatagac ttgcaaggcg cgttttaact cctccttagc atctacatct
     9001 aaatgattgg ttggctcatc taggattaaa acattgtgct cacgattcat taagagacaa
     9061 aaacgaacct tggcttgctc accacccgag agcccctgaa tctggctttc aatatgctta
     9121 gaggttagac cgcaacgagc taaggctgcc cgaacctctg cttgatttaa agcaggaaaa
     9181 gcgtcccata ctgcttctag tggcgtttga cgcttaacac ctgcagtttc ttgctcaaaa
     9241 taaccaagct ccacgaaatc tcctgtttcc acctctcctg acagtggctg aataatgcca
     9301 agcaggctct ttaggagggt tgacttacca ataccattag caccgataat tgcaactttt
     9361 tgatgacgct caaatgttaa gttcaaggga tcttttgtta ggggtctgtc atagccgatg
     9421 acaagctccc ttgtttggaa aataaagcgg cttggtgttc ttgcttcctt aaactcaaag
     9481 cttggctttg gtttttctgc ctgaagctca atgatttcca ttttatcaag cttcttttga
     9541 cgggacatag ccatattgcg agtagctact ctggccttat tacgattgac aaaatcctgt
     9601 agctctgcaa tctctttttg ctgacgctca taggctgcct ctagctgagc ttttttcatc
     9661 tcatagactt ccttaaactg atcgtaattt ccagaatacc taaccaaatt ccgattatca
     9721 acatgataaa caatattaat gacatcattt aaaaaaggaa tatcatgtga aatgagcaca
     9781 aaggcattgt cataatgctg taaatagcgc tttaaccact caatatgctc agcatcaaga
     9841 taattggtcg gctcgtccag cagcaaaata tctggcttct ccagtaacag cttggccagc
     9901 agaatcttgg ttctttgccc tccagataag gaggtcactt ctgtttccat cccaaaatcc
     9961 ataactccta aggcacgcgc aacctcatca atcttagcat ctagggtata aaagtccctg
    10021 ctttcaagac ggtcctgtag ctctccgacc tcctccatta aggcgtcgac atcagctgtc
    10081 tcctctgcca tagacatgta aatggcattg atacgctcct ctgttttgaa tagctcatca
    10141 aaggctgtcc taagaacatc acgcacagtt tgaccaggtt ctaaaacggt atgctgatcc
    10201 aaatagcctg ctgtaacata ctttgaccat tcaatcttac cagcatcagg ctgcaagtga
    10261 ccagtaacaa tactcataaa ggtggacttg ccttctccat ttgctcctac taatccaata
    10321 tgctcgccct ttaaaagacg aaaggaaaca tcttcaaaaa tggcacgatc accaaatcca
    10381 tgacttaact gcttaacttc taatatgctc atgattactt tcctttattg tcatcaaaaa
    10441 agccgttaaa acggcttaca ctctctcaat tatggcaaaa atgcagcctt ttgtcaatga
    10501 aggctgaaaa agcctacgtc atacgcatga aagattttta gcaagaacag aaggtttttt
    10561 gcattttaat gttcagctat ttcaaatatg tcttattatt ttataaattt tactataggg
    10621 aaagccttga aagtgcctgc tttaatttat actatcattc ggaaagaact gtttcgctcg
    10681 tttgttgtgg aaagccgctc acaacaaaga catagagagt ctatgacaac aagagctaca
    10741 ctttagcaag tcttgaccga catgctttat tgcccagtct aattcattaa aaagcgaaca
    10801 ggtctagctt tcggaatttc agaaaactag gcctgttcat ttgttctatt ttgaggcagc
    10861 cttttgtttc ggcctcgtct gtttcaaggt tttcagatcg aacttaagga caaaaaacac
    10921 tctcctgtat cagctaacct tatcattcat tataaaggaa aatgatttct aatacaagga
    10981 aataccgtta tttcattaaa aataactaaa aatagtttgt caaatcatta gttattaata
    11041 ggcttagata acaaaaatga tgatactgct agcaaggtta gctcaaccaa gcctattact
    11101 cgcttcttgc ttttttactg cctgccttaa ttgcttaaaa acagggtata agagaggcac
    11161 agcaataacg gtcacaaggg cagtaccaag actgccacca attttgccaa gtgctgccca
    11221 caaagcaaca gacaggggta actgggcgcc aaaataagca atcaagctat atttcacaag
    11281 attcatgact aattttgctg ctgctgctaa taagccaatt gctacaataa tcatcggttt
    11341 atcaactgat ttcagaagtt tctcataaat cacatgaagc aggtaacaaa ccactaaggc
    11401 ttcaagcact gttatccaga ccacagccgc atagccatta atcatatcaa acagtcctag
    11461 accaatggct gccaccaaag ctgcccttct agcaccatac aataaaacag ccaccaccac
    11521 taaggcattc cctaggtgaa taaattgggc tccaactgga atacgcagca gctcaaccga
    11581 tataaaaata agagcagcaa ataggctaag ctcgatctga tcagtcaatc gttttgatgt
    11641 catctttttc ctccaataat cctctaaacg cggctcccaa gctgcccaat tctacttcgt
    11701 aggcaattcc aagtgaaagc tctcgattta gcgcaacagt agccgctaat gacttgtcta
    11761 agaagctaat aaccatatcc aacaactcat caatagcaag cctgtgaaaa tacccagcgc
    11821 taacaatagc agagacaaga tcacctgtcc catagaaatg ataagggtac cgttttccaa
    11881 aatgatagct aaccgtctct gttgcctttt gataataagc aaagccgatg tgctgatcat
    11941 caaaggatat accagtaagg acaatctctc taggtcctag tgtagctagc ttagacaata
    12001 gcctctccaa atcctctctg ctataggtct ccccaaaata aggaacatca gctaacaaac
    12061 aagcttccgt cacatttggc aatatcagct gtgcagcttg agcgagcaat ctcattgccg
    12121 ataagtgctg cgaggttaac tgcgcataca tgcttccctt gtcagccata ataggatcta
    12181 gcacaaaggg aagctgttgc tttttgatgt aatcaagaat aatcaaagca tcatcaggac
    12241 ggtacaaata accggaaaaa aagccatcaa aggcaagacc cgcttgagac caagtcgtca
    12301 aaaatggctt tagtccctct gacgtgctct gaatataagg cgtcttagca attgcagtgt
    12361 ggcttgataa caaacaggtt ggaagaatgg cctgttcaat ctggcaagcc gccataatgg
    12421 gaatactagc agacagagca accttgccaa ctccgacaat atcatttgca acaataacac
    12481 gttttaacaa ccaataagct ccttcatttc tttttttact attgtaagaa aatccttgat
    12541 gagatacaat aaggatagat ttcatctgta tggggacact tatgacaagt aaatatcaac
    12601 aaatcattgc agacctagag ttggccatgc aatcaaacca attcaaaaag ggagagaaac
    12661 tcccttctat tagacaatta agtcaacagt atcactgcag caaggataca gtgcaaagag
    12721 cacttttagc cttacaatac aagcgcctca tttatgctat tccaaaaagt ggctattatg
    12781 tgcttggtaa aattgaggaa aagcagcatt cctttgagct aagccttgag gattataatc
    12841 agttggccta tgaggacttt cggctctgtc taaatgaagc cctagacggt aaagattctg
    12901 atttatttaa ctactatcat aaggctgagg gacttgagga gctgcgagag gctttgctgc
    12961 cttatttggc tgataatggg atttacgcta acaaaaatca gctgctaatt acctcgggta
    13021 cacaacaggc cctttacatt ttagctcaaa tgagatttcc caatggccgc catcacattc
    13081 tccttgagac accgacctat caccgaatgg agcagctagc gacttcctta ggcttaccct
    13141 atcaaaccat tgaacgtgat gtcaacggta tcaatcttca tcagcttgaa agcatcttta
    13201 aaaccggaca aatcgctttt ttctatacta tttctcgatt ttcaaaccct cttggcctct
    13261 cctacagcaa aaaagaaaag gaaagcattg ttcggctggc agagcaatac caggtttaca
    13321 tcgtagagga cgattatcta ggggactttg catcgcatag tgagcttccg ctacactact
    13381 acgacactca acaccgggtc atttatctga aatcattttc aatgagcgtc tttcctgccc
    13441 tgcgcattgg agccttgctt ttacctgatg atctcaagga aggctttttg ttacaaaagt
    13501 caatgattga ccttgatacc aacctgatca tgcaaaaggc actagcatta tatttagcaa
    13561 atggtatgtt tcaaaaaaac ctaaagcaaa tgaggcaatt tttcaacaat agagcgcata
    13621 acttactaga ttttctacaa aaacaccttc ctaacctagc ttatcagctc actcctcaag
    13681 cactgattat tcaattagat aaagcattca atcgcaaaaa gcttcttaaa ccacaccaca
    13741 cccaaatcat ctcaacaaga aaagcaaggt atatgcttct aacaatcagt cctgatatgc
    13801 catctaagct gctcgacttg ttttcagtga cacatgaaaa gacccaagaa tagctcattg
    13861 ggtctcagtg tcacaaaaat gtcaatagct atttgatttg ctcgaatcgt aaatgaacac
    13921 taatgctatc gccgtaaccg tttctctcca aatctctttg gagccggtaa gcaatataat
    13981 gctctgcaat agtcatgtag cctgcgtcaa tcagacgatt ttcaacaagt gattgaatca
    14041 tattaatcgt cggacgctcc gcctgcacct cttctagatc aataacaacc tttttagtta
    14101 cctgagctag atgctgtctc cagctgtcat caatcacata aactgttctt gctgccttga
    14161 tcaaagcctg ataaatctta tccggatcaa agtctgccag ctgaccgtca cgcttaataa
    14221 tttgcataag agcgcctctt ttcatttagt ttcattgctt acattcatta tgcaaatgtt
    14281 ttcatcattt gtcaagctat taggctccta tgcctcttag ggattatcag tcaaaagaaa
    14341 cactaggatc aaataaattg tcctgtgctg gtcggacaag cccacgctcg tgcaaggtct
    14401 ctgcaatctg aacagaattc caggctgcgc ccttgagcag attgtcagat accacccaca
    14461 tgtgaatgcc cttttcaaca tctaaatcct tacgaagcct tcctacaaag gtctcacgac
    14521 tgccaacagc attaacggcc tgtgggtatc gttgcactcc ggtatcgtcc tctaaaacag
    14581 cacccggaaa ttgtgcaatc gcctccttaa cagcttcgat agtagctact gccttggttt
    14641 caatgtagat agattctgaa tgggctgata aaacgggtat acgaacacag gtcgcagaca
    14701 ccttaatcgt atcgtcctcc atgatttttt tcgtttcatt tgtcattttc atctcttcat
    14761 aggtgtagtc attttcagtg aaacgatcaa tctgtggtaa agcattaaaa gcaattggat
    14821 aatgtctctt gtcaccagct gacggtaaaa cacttgcctc cacctcctta ggagacaagc
    14881 cctggttaat aacctggtca tactgagcta gggtctcacg aatcgctgat tgaccagcac
    14941 ctgaaacagc ctgataggtg gaaacaataa tacgctcaag accccacctt tgacgaatag
    15001 gctccagcgc tatcatcatt tgaatcgtag agcaattagg gcaagcaaca aggccttgat
    15061 gtgtatcaag agcgtgagca tttacctcag gaacaacaag tggaacagct gggtgctgac
    15121 gaaaataaga ggtattgtca accacaacag cacctgccgc aacagcataa ggggcatatt
    15181 ttgcagaaac attgcctcct gctgaaaaaa gggctagatc aatgccttgg aaggctgctt
    15241 ttgttagctc ctcaacaaca aaatcctctc ccttaaatga gaggattttt cctgctgaac
    15301 gtgcagacgc taataattta atagctgaaa taggcagact tgactcctcc agcatcttaa
    15361 tcatttgctg accgacagcg cctgtcgctc caaccactgc tactgtatac cccatagatc
    15421 gacctcactt taactgatga tattgcaaaa aatgatattg gacctattat agcctatttc
    15481 atcacaaaag aaaagcaagc tagaagccag aacaaacgca tgaagaaaat catttattga
    15541 aaaagttgtg aaaatagcaa aatatccatt ttagagtatt ttgacagagt gtttcctgaa
    15601 tttttatatt tttcctctat aaacttttct tgaaaaa
//
LOCUS       DARYXZ010000050        15097 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYXZ010000050 DARYXZ010000000
VERSION     DARYXZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15097
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(220..1320)
                     /locus_tag="TV186_001614"
     CDS             complement(220..1320)
                     /locus_tag="TV186_001614"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1532991.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1317..1673)
                     /locus_tag="TV186_001615"
     CDS             complement(1317..1673)
                     /locus_tag="TV186_001615"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL1532992.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TV186_001616"
     CDS             complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TV186_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL1532993.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TV186_001617"
     CDS             complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TV186_001617"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL1532994.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5753..6637)
                     /locus_tag="TV186_001618"
     CDS             complement(5753..6637)
                     /locus_tag="TV186_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1532995.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6994..10050)
                     /locus_tag="TV186_001619"
     CDS             complement(6994..10050)
                     /locus_tag="TV186_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1532996.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEERWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYGSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGRYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10279..12162)
                     /locus_tag="TV186_001620"
     CDS             complement(10279..12162)
                     /locus_tag="TV186_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1532997.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12439..13878
                     /locus_tag="TV186_001621"
     CDS             12439..13878
                     /locus_tag="TV186_001621"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL1532998.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13883..14848
                     /locus_tag="TV186_001622"
     CDS             13883..14848
                     /locus_tag="TV186_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1532999.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
BASE COUNT         4306 a         3770 c         2859 g         4162 t
ORIGIN      
        1 tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg ataaaggtaa
       61 gggccttttc ttattctttt tcttaacccg cagaaaaaca agacctgtct tgatctgctc
      121 tatctatgct gttagcctga ggtctcaaga cctttacagg actaatcatt tgaaagacag
      181 ccttgaggcc agtcaatagt tgagcctagg ctcaatttcc taatattctc taggaatacg
      241 atcactcagc aagcaaagca cctcataatt aatcgtacct ctataatcgg caacatcggt
      301 tgctgtgatt acttgtttac cctgctgtcc aatcaaggtc accttagtgc cgataggata
      361 ggctttaggc aaacgaatgg tcaattggtc catcgacaca cgaccaataa tgtcacaaaa
      421 ttccccttct accaatacct taaagccctg catatttcga gtccaaccgt cagcatagcc
      481 gataggtaag gtcccgacat actctggttc tgctgctaca tagctagctc catagccaac
      541 gctatcccct gcctgaattt gcttcacatg aaccaaacgt gattctaagg acaaggcttc
      601 ctttaaggga caaggtagac tcaagctatt gccgcttgga ttgagtccat agataacaat
      661 accaaggcga atggcattaa aaattgtttc actatgccaa aggcttgttg cagagttgct
      721 tgcatgcact aatgcaggcc tcttatctag ctgctccacc aactgcttga aaaaggtcag
      781 ctgcttatcg aacatggcat ggtcagagtc atctgcggtt gcaaaatgcg tgaaaatccc
      841 gtcaagctgc actcccatat cggataagat tgagatgagc tgattggcct cagcaagcga
      901 cctgacacca atgcgcccca ttcccgagtc aaccttgaca tgcacatgaa gctgactgaa
      961 atcaaccgat tcctttttgg caagctctag ccactctaag ctggccactg ttatcgtcag
     1021 ctgatgctta atggctagct gcaattcact tgctaaaatc acccctaaaa taaggatttc
     1081 cttatcaatg cctgcctgac gtaattccaa ggcttcatca aggtttgata cgcaatagcc
     1141 atcaacctga tcctcaactg ccttggacac tgcaactgcc ccatgaccat aagcattggc
     1201 cttgacaaca gcatatgtcc ttaccttttt aggaatatgc tgatgaatat ggtcaatatt
     1261 tgctcgaata gcttctaagt caactctagc tactgttggt cgatgtaagc ttgaaatcat
     1321 gctaaatcct ccaaaataac acttgcttga acatagcccc cactatgtga aatactgata
     1381 aaggccttac cctgaaaggg agattttgta atgacgggac gccctttgct gtcattgata
     1441 atttcaatat cctgaaaggt tagctggcca atccctgtcc ccattgcctt tgaaaaggcc
     1501 tccttaccag cccagcggcc ggccagatag gtcatttttc ggtgatggga aaattgctca
     1561 aacagcgcta gctccttgtc cgtcaaaacc tttctagcaa atctagcatt tctcaaataa
     1621 accttttcaa tagctgaaat atcctgtaaa tctatcccat gtccaacaat catttgcctt
     1681 tattttacca gccttcactt taatttaggg aaacaaatcc taaacaagga gaagccgaga
     1741 acaaatctca gctcctcaca ggttttcaac atggccatca cgctatcctt aaaaagcctt
     1801 acgaccatga cagtttttaa acttcttacc agagtgacaa ggacaagcat cattgcgctc
     1861 gactcttgaa aaatcagctg atgaatcaaa atcagcaccg atagcctgcg actgaatgtt
     1921 ttgtgctgca gttgttgttg catactgaat tgcacgctcg cgctcctgct catgaatctg
     1981 tgccttcatc atggtacgtg taacatcaaa ttcgatagca ccaatcatat cctgaaacat
     2041 cttgaagcct tcactttgat attcaacaac tggattattt tgcgcataac cacgcaaacc
     2101 aaccgcatta cgaagctggt ctaaggcatc aatatgctct gtccatttgt tgtcaacaat
     2161 catcaaaatc agcaccttct ggaattctaa gatagcgtcc tgatcgcgca attttgataa
     2221 ctgcttatcg taaatctcaa gggcacgctg atagagcttg tctttgatct gatcgtcctt
     2281 gaggccacgc aattccttag caccgatggt ttcctctggg acaattgatg ttctcgcaaa
     2341 agtcacgatg gcgtcaatag cgtccttacg attggtacgt gagtgggcat caactgctcg
     2401 atcaatcgta cgcttgatca ttgccttaat ttcaggacct aggtcacgat ttgctgtgat
     2461 aacatcacga cggttagcgt aaataatctc acgctgctca cgcatcacat catcatactg
     2521 caagacctgc ttacgtgtgt catagttatt accctcaaca cgtttttgag ctgactccac
     2581 ctggcgtgac agcattctgg acttgataac aatatcctcg tcatcattgt tcatacgatc
     2641 caagaaagcc ttaatacggt ctgtaccaaa gcgcctcatc agctcgtcct ctaaggagag
     2701 gtagaattgt gactcccctg gatctccctg acgacctgaa cgcccacgaa gctgattatc
     2761 aatacggcgg ctctcatgac gctctgtccc gataacacaa agcccaccga gctctcggac
     2821 accctcaccg agcttaatgt ctgtcccacg accagccata ttggtcgcaa tcgttaccgc
     2881 accacgctga ccagcattca taataatctg tgcttcttta aagtggttct tagcatttaa
     2941 gacctcatgc ggaatgcctg cttctactag ctttttagaa atcaggtcac tggtctcaac
     3001 agcaactgta ccaactagaa cgggctgccc cttttcatag cgagccttaa catctgcaac
     3061 cactgccttg aattttgaat tcaacgttgc ataaagaagg tctgtgtgat caatacgagc
     3121 aataggacgg ttggttggaa tcggaataat acgcatgttg taaacttcgc ggaattcctc
     3181 ttcctccgtt tttgctgtac cagtcatacc cgccaatttc ttatacatac ggaacatgtt
     3241 ttggtaggta atagaggcac ttgtttttga ttcctcttga atacgaacgc cctcttttgc
     3301 ctcaatagct tggtgtaagc catccgaaaa gcgtcgtccc tccattgtac gacctgtaaa
     3361 ctggtctaca atcaaaatct cgccttcctc gctaaccaca taatcaatat ccaaaagcat
     3421 gatataatta gcacgaaggg cattatccac gaagtgggtc aaggcaacat tttcaatatc
     3481 gtataggttg ctgaggttga aatagctttc tgccttatca atacctgagt cgcttaggcc
     3541 aatcgtcttg gtcggaacat caatgatgta atccactgaa tccaaggtct tgacaaacat
     3601 gtctgcacga atatagagct gattcgtttc tgagctcaca gcaccagata caatcagagg
     3661 tgttcttgcc tcgtcaatca aaacagagtc aacctcatcg accaaggcaa agttcagtgg
     3721 tcgctgaacc atgtcctctt gacgaaccac catattatca cgcaggtagt caaagcctac
     3781 ctcagagttg gttgagtagg taatatcaca tagataagcc tcacgctttt cagctggtga
     3841 tttggctgct aggttgatac cgactgaaag ccctagccag ctatacacct ctcccatctc
     3901 tgtcgcgtca cgagttgaca agtattcatt aacagtgata acgtgtaccc cttcgccagc
     3961 aagggcatta aggtaaacag gcatggtcgc tgtaagggtc ttaccttcac cggtacgcat
     4021 ctcagggaca tctccattgt gcaagacaac cccccccatg atctgaacac gataagggta
     4081 aagtcccagc acacgtctag ccgcctcgcg gacaaccgca aatgcttctg gtaataactg
     4141 ctcaagggtt tccccatttt gataacgttg tttaaattcg ggcgtttttg cttgtaggtc
     4201 tttatctgac aaggactcca tatagtcagc ataggactct acttttttcg caattttttc
     4261 taattttcgt aattcgcctt tatcattttc aatgactttg cgtagaatat tgctcattct
     4321 ctttcctttc gatcgactaa tcattttatt ctaacataaa taggcaggca gttcaagaaa
     4381 tgatcataag atatccatga cagacgcatg aagaaaatca tttattgaaa aagttgtgaa
     4441 aatagcaaaa tagccatttt agggtatttg acagagtgtt tcctgaattg ttatattctc
     4501 cctctataaa cttttcttga aaaatttctt ttctgcaact atcgctatgg ctttcctatt
     4561 tttcagaata agttttcgca ttcagaaata tcttggaaat tttttcttca tgcgtctgtc
     4621 gtgataagat atcagaaaaa gaaaggccgc ttgtccaaac agtctttctt ggtgttttcg
     4681 tgtattctgt acttaattag gatgactgac aatcatttcc agctgaccat caaagctcca
     4741 tgacgtcaca tcatttggca ggataaaatg catacccttt tgaagctcgt aaacagcttg
     4801 atcaatcgta aggcttccct gaccagctag cacactgaca agcaggtaag gggctgattg
     4861 cttcatgctg actgcttgat caatctccca tttgtaaact gtaaagaagg gattagatac
     4921 taagcaggta gagaccaagt gctcaagttc tagtgtggct ggcgtgctgt tctcaggctt
     4981 gccaatagtt aggacatcga tagatttctc aatatggagc tcacgaagct gaccttcagc
     5041 gtctcgacga tcaaaatcat aaacgcgata ggtcgtgtct gaggattgct gcgtctctaa
     5101 gatcaaaatt cccttaccaa tggcatgcat cgtgccgctt ggaacataga agaaatcacc
     5161 agccttaacc ggaactcgcg tcaacaactc ttcccagttc cccgcctcaa tcatcgcacg
     5221 aagctcttgt ttagagcttg catgatgacc ataaacaatc tcagcgcctt cttcagctga
     5281 aataatatac cagcattccg tctttcctag ctctccctca tgggccagcc cataagcatc
     5341 atctgggtgt acctgaacgc ttagccagtc attagcatct aaaatcttcg tcaacagcgg
     5401 aaagaccttt tcctttggat ttccaaatag ctctggtctt tctgcataaa gctgatctag
     5461 cctttggcct tggtagctac cactgctaac tgtggaaaca ccattagggt gagctgagat
     5521 tgcccaatac tccccagtgg tttcggttgg aagctcatac ccaaacacct ctcttagctt
     5581 tgttccgccc cagatcttat catgcatgca tgatgttaaa aataatggtt ctgacatagt
     5641 aatcctcatt ctcttttcac taacctatgg tgacattctt tgccccaatt ctaccaattt
     5701 caggcacatt ttgcaaatga ctctaggact tttatcaaat aggctcaagt atctagctct
     5761 tttcagcaat cagctttgct aaagcaaaat tcccaagagt ggccgagcca ttacctgcaa
     5821 ctgctggtgt gaccaaatat tctctaacat cagctactgg taaataacca ttaatcagtc
     5881 tggtaaaggc ctcctgaaca cgcaccagca tgtgctcctg tgccatcaca cctccaccaa
     5941 acacaataac ctgaggacga taaagcagcg ttgcctgtac agcagcctga gctatataga
     6001 aggcttgaat atcccaaaca gcggccttct gatcaagaag ctccccctta atccctgccc
     6061 ttgcttcaag gcttggccct gctgccatgc cctctaagca cccccgatga aatggacaaa
     6121 cacccaaaaa tgcattcgcc acatcgtcaa ggtgctgcat aacataggta tgtcccgcct
     6181 ctgtatgacc taacccaccg ataaactcac ctttttgaat agctccagca ccaatacctg
     6241 ttccaatcgt ataataaaca agactgtcaa catcaggtcg agagatagcc tccccatagg
     6301 cagaactatt aacatcagtc gtcacataaa aaggaatcgc aaaggctgct gtcagctgcc
     6361 ctaatagatc tacatttgcc caacctggct tgggtgttgt ggtaatgtag ccataggtag
     6421 ctgacttagg atcaatatca atcggtccaa aggagccaat agcaatacta gccaagtcgg
     6481 cctcaaattg cttaaaataa gcaatcgtac gctcaatagt ctcttttgga cttgtcgttg
     6541 gaaattgcac cttatccaca acagcaaaat ccctatcacc aacagcacag acaaactttg
     6601 tcccgcctgc ttcaatactt ccaagtaatg ttttcatctt ttctccttaa taatagtgat
     6661 aagccctgtg ctggttattc tcacaaggct caaaatccca ccagctaatc agcagctacc
     6721 ttagtagcta aacatcatcg cttgcttcct tgcctcctag aaaagaccaa aaatctggga
     6781 taggactatc tcagattttt gatatgcctt taagagataa ggcaattgat tttaggaggg
     6841 aaaccttggc agcaggagct gccaccaaga agcagcacaa acaattgctt ttaatggtgt
     6901 gttcatcgcc ttatctctaa agcttaatgt gttagcgtaa tgatcagtaa cctcaagcta
     6961 acggccaaga acgacagcct gctcaaggat aagctagtct gtctttggat tttctggctc
     7021 agtattttct tttatgtcag tagccacagg ctgctcaact ttagctgctt tagctacttt
     7081 ttcctgatca gttctatcag ctaaaagctt atcaacataa gccttcagat cagcagtact
     7141 agcgttaata gcatcggcat taaacatctt actatctaaa gcagccttta aggcagctat
     7201 tttgacttcg agctccttaa gctgctcttg agagaacttg tctttttgct gagatagctc
     7261 ctctgcagta gctagcattg ccatcacaag atccgcagcc ggtaattgat aaccaatgat
     7321 ttgaagctca ggaagtgatg gccaattgta acgtcctccc ttagtatcaa ctgttattct
     7381 ccaatatttg gcaccaatgt tgtttaacgg ctggctaaac tcttggtcct ctcctgaata
     7441 atctgaaact gttacccatt ttgatgattt ttccaagcta tcctttacct ttgagccagc
     7501 ttcaagatgg ccaacaaagg cttcaagctt ggcctcctta atacagtcag ctttactaat
     7561 tttgctgtca ttaaagaaac gccaatactt gactaagcca ggctctttaa gttcaaaaat
     7621 gatagaagct ttattgctag ttgacagaat tgttgtatca ttattgagca aaccatcaaa
     7681 cacttttttt gcatttgttg gatctgcatc accaccaatc acagttgctc cctctgctag
     7741 gttaaccatc atggtttttt ccgcaccaac gacaacctta gcctcatgca caggcttagt
     7801 gctattagta gggctaaaga attcaacctt gtaggtctcc tccttgctag tggataagtc
     7861 cttgtgatca gtgacaccta aggttgagtc agtcaccttg atcttatagt ccttgtaggt
     7921 cactgcaaag gctttgtaat catagcttga atcaacaaaa cggtgacctg ctatttcctg
     7981 ctcctgataa gccttatagt cagcttcgct attgattagc gtgccctgat tggtaactgt
     8041 tccaaataaa agcttagcct gcaaatcaat tgtatcattt gctactggta actgaaggct
     8101 cttagtgcca taagtatcag gataaagacc agtaggcttt tgatgatcaa atacaaacgt
     8161 cttttcgcta acaccgccat gcttagtcac tgttgccagc atggtatcaa gaatctgacg
     8221 attttccgta ccagctgcta agtccagctt attactagag agatccacct tttcaagaga
     8281 ggttaggcta gctgcgtcaa ttccagccaa gctatcacga tcaaagccag caagatttaa
     8341 ttccttcaag ccagttagac cagaaatggt cagagccacc tgtggaatcg ccttagtctc
     8401 ttccttctta gcgctgccgt aggcttcaag aacattggcc agcgtatcct tggtcggctt
     8461 agcatttgca ggtaggacta agctatccag ctttgtgatt tgtgatagac cgattagctc
     8521 tagcttagct agttttttaa gcttattcag gccttctaaa ctcttgatat ccggattgtc
     8581 taagcgcagg gttccattga accgctctaa atcccctctt ctgcttccaa cctgtgcaat
     8641 aactgcttct cgcaaagcct tgtctggaaa atctttctga tcaatcagct cataggattt
     8701 gtcattttcc ataaccttct tcaaggcctt agaaacctta taatctgatt tgacaatacc
     8761 atctgttata tcctttatag ccttgttagt tcttttctca tcatctgaga cttttttagg
     8821 ttgatgcgct acaccatcgc gatcaatcgc ataagagaaa atccctccct tgacaccacc
     8881 tgtcttaggc tgccattttg cataacgctc agcacgagta ccagctatct ctgaatttaa
     8941 cggattatga tcatctttcc tctcattaat atcataccag aggttaccac tgcccgcatt
     9001 ttcctcatag aaagaaaaac caaccatgta ctgctcagga cgaatgtatt tgctatacga
     9061 ttcccaacgt tcctccattg tcttttcagg ttttctagcg actggatccc aatctccctt
     9121 ctcaccttga gtgccataaa cctgcacaag cagcaaatca atatattggg caccgcgctc
     9181 aatcaatggg ttcttgtcag ccatgtaggt gctatccata atgaacaaac gtgacttgtc
     9241 agcgcccttt ggcccaataa gcttgccaat ttcttcaaaa acagcaatag agcgctgaat
     9301 attttcgtta ctctcttttc catttacttt tggaatgcta tcccgctcaa tatcaacatc
     9361 taaaccatca agattatatt tataaacgta ttcatctaca atagcctttg ccaaggcctt
     9421 atttccctct ggagtatttg ggtatttttg cgtatcttca gcaataccac tatgatcacc
     9481 gcctgcaagg aaccgccatg gaatggtacg aatcacacgt gttccctgct tgttcagcgt
     9541 tggcacatgc ttggtcgcca attcttgcca gaaaaagcta taatccttgg tccaatcatg
     9601 gaaaacaaag gctaagtcaa cctccttagg caattctccc atagaattaa ccttatcctt
     9661 ttcagccgga tctgatgttt tatcatgcca agtcctaaaa tagccaccat aaagaggccc
     9721 ctttaaaggc ttcatggcta ttttttcagg aaccttcatt tctgcaagaa cctttgcctg
     9781 cttatctgcc tgctgtgcct tggataaaat atcctttagc ttttcaggta cttctcctgc
     9841 ctttgataac ccctccttaa attctttttt actgttttcc gacaggtaat gtaggtcatc
     9901 aatagcagag actgatggac tagtttgcac aaccttatcc tctgccttga cccttatgag
     9961 tgaatcatgt tgggcagcta atatagccac cattaacgct gcagcacaaa cacatttcag
    10021 tgttttcttg actaacacct gtttttccat tgggacactc ctttattttg ataccaaaga
    10081 atggcaaatc tttgctgaac caaaaatgta agcgcattct ctgcgttcgt ctaaagtata
    10141 gtagacctca tgatcaaaag caatgcacaa agtataggta aaataaaaga aacttaaggt
    10201 cttttaattt ctgtaatttt atggtgaata ttttaatctt acatgtaaaa agagatgaaa
    10261 tcatcaactc ttttcaaatt attttacaag gatcactgga ctgccaacag tcaccttacc
    10321 ttgtgccaaa atctgaacag catgaacatc tgcgctattg gtgacaagca gcatggttgt
    10381 agtatcaagg cccgcctgct gaatccttgc aatatcaaag cttccaagag catcaccagc
    10441 cttgaccatc tgaccaacct taacaaaggt ttcaaagccc tcacctgcca ttgaaacggt
    10501 atcaatacca atatgcagta ggatttctgc tcccttatct gatttgatga cgtaagcatg
    10561 acctgtctca agggcagcct ctaccctgcc atctaccggt gagcagagaa tgcgcccttc
    10621 aggcttgatg gcaacgcctt ggcccatgct tcctgacgaa aagacaggat cagcaaccga
    10681 tgacaaatca atcaactccc ctgcaactgg actaagcagc tcctcagcag cagaggcttt
    10741 ttgcgcaggc tctgatttta cttgggtagc cggtgcttct tggtcactct tgtccttgaa
    10801 tccccaaata taggcaatca caaaagctag accaagccca accaacagtg tcacaaggta
    10861 ctgtagtagc tgaccattaa gatacagcag tgcaccaggc aaaaccgtaa tcccaaagcc
    10921 ggtaccagca atgccaagaa tccctgcaac ccagccacca gctgcgcccc cgataagtcc
    10981 tgagacaaat acctttgggt agcggagatt aaccccaaag atagccggct cagtaatccc
    11041 taaaagagct gacagagctg atggaaaggc taaacccttt aattttgcag acttggtttt
    11101 aacagcaacc gctagagttg ctcctgcttg ggcggccgta gcagctgtca aataagcgtt
    11161 aaagggatcc tttcctgtat tggcaactag ctgcgcctcc aagaaattga aaatatgatg
    11221 gatacctgtc acaacaatca gctgctgaac acccccaata acaaggccgg caatcccaaa
    11281 aggcagacct aaaactgctt gtgtccctgc aagaacaagg ttttccaagg agtgaaagat
    11341 aggcccaatc acaaagagcc ccaaggcact cataatagca aaggtcaaaa acggcgttgc
    11401 caacaaatca agcgcatcag gcacccgctt atgcagccac ttttccagct tggcaccaac
    11461 cagaccaaca aagaaggctg gcaataccgt accttgataa ccaacaactg gaacaaaacc
    11521 aaagaaagtt aagggcttaa catcacctcc tgaggctacc acccaagcat ttggcaactc
    11581 attagagacg agcatcaagc caaggacaat cccaatgata gggttgccac caaataccct
    11641 aaaggctgac caagcaacca aggccggcag gtagacaaag gccgtatctg ttaaaatccg
    11701 agtgtacatg aggaaattgt cgccatagtc atgaatacca aagaactcca taacagccgg
    11761 ctgcgtcaag agaccccgta cacccataaa cagccctatc gccacaatag caggaatgat
    11821 cggaacaaag acatcaccaa aggtacgaat agcccgctga aaggcatttc cagacttgac
    11881 cacttgctcc ttttgctcac ctgccaaagc agctggaagc cctagagcta caacctcatc
    11941 ataaatgcta ttaaccgtac ctgtcccaaa aatcagctga tattggcctg agttgaaaaa
    12001 agcaccctta accttatcaa tagcctctgc tttttcctta ttgatcttac cctcgtcatg
    12061 aaccataacc cgcagccgcg tcgcacaatg agccacactt ctgacatttt cacgaccgcc
    12121 taaggcctcg ataacctctt ttgcaatctg atgattatcc ataccgatag catctccttt
    12181 tttgtctgtt atagtctatc gaaatagctt ttcttgagcc tatccaatat tggcggacct
    12241 accctactgt ccgactcaag atggtctttc aatttactat tgtgaatccg cttcacttct
    12301 tgctatcatt ttaacacgaa tattttttat gtcaagcgtt tgacatatat tttgtttaaa
    12361 ataattaaaa aagttgattt ttagagagaa aacgtttatc atatgaataa aaatgaccaa
    12421 tacctaagga gacctgacat ggatttacca agatctattc gctaccgacc atatcaagaa
    12481 tggagcaagg aagcctatca agcaatccaa caaaaggtgg cccagtcttt atggcgcagc
    12541 catttccata tagaagctcg tacaggtctc ctcaatgacc caaatggctt ttcttatttt
    12601 gctggcagct ttcagctttt ctatcaaaat tggccctttg gagcagctca tggtctaaag
    12661 caatgggtac acaccacatc aactgacttg gtgcatttta cagaaaccaa aactcggttg
    12721 ctgccggatc atcaaaacga tagtcatggc gcttattccg gctctgctta tcctattggt
    12781 gacaaactct ttttatgcta tacaggaaat gtccgcagca aggattgggt acgccaccca
    12841 ctacaaatag gtgcctggat ggaccaatca ggccacatca caaaatgtga gcaggtgctc
    12901 attgacaagc cagatgatgt cacagagcat tttcgtgacc cccagctctt tacctaccaa
    12961 gatcagcttt atgccatcat tggtgcacag aatttgcaac aacaaggtat cattaagctc
    13021 tacaaggcta acaacaatga tgtcaccagc tggcaatttg ttgctgactt ggattttgat
    13081 gactcaggca ccgcatacat gattgaatgc cctaatttgg ttttcattga agataagcct
    13141 gtgcttatct tctgccctca ggggcttgcc aaatcagagc ttgattacca aaacatttat
    13201 cccaatacct ataaggtatt tcagaccttt gatcctaaaa gacgcaagct ccttggggga
    13261 ggtccaatcc aaaaccttga ttttggattt gaagcttatg cgacacaggc ctttaatagc
    13321 cctgatggta gggtactggc agtttcttgg attggcctgc cggacatcga ctacccaacc
    13381 gataaatatg cctaccaggg agcgcttagt ctagtcaagg aattacgact caaaaatgga
    13441 aggctacacc aagcaccagt ccctgctctc agtaagctac gagacaaagc ccagcccttt
    13501 cagaacaaaa aaaacagctc aaactgctat gagctggctt tgaccattga agcacagcaa
    13561 gcaacagagc ttttgctctt tgccgataca cagcacaagg ggctgaaact gaccgttgac
    13621 acctgcaaag gacagctaac aattgatcgc agcaaggcag gcgcccagta tgcccaggaa
    13681 tttggagcaa agcggtcttg ccaaattcct gtcaatcgtg ctacacttaa tatctacgta
    13741 gacaagtcta ttctagagat ttttgtcaac caaggcgaag cagtcctcac gagtcgtgtc
    13801 tttccaaatg aggggcagtc tggcattgag ctgctaaagg gccaggtgag tggctactat
    13861 tatgaaatga ggtactagac aagtggtcgc aaaattaaca gatgttgcag cattagctgg
    13921 tgttagccca acaacagtct cacgtgtgat taacaaaaaa ggctatctgt cccagaaaac
    13981 cattgataag gtgaacaaag ccatgcgaga gcttggctac aagccaaata acctcgcacg
    14041 aagcctgcag ggcaaatccc ctcagctcat tgggctgatc tttcctaaca ttagtaatat
    14101 tttttacgcg gaattgattg agcatttaga aatcgagctc tttaagcaag gttataaagc
    14161 catcatttgc aacagtgaaa acaacccgat caaagaacga gattatttag aaatgctagc
    14221 tgccaatcag gttgacggca ttatctcatc aagccataac ctaggtattg atgattatga
    14281 gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc gctcctcata tccccatcat
    14341 atcctctgat aattttgaag gagggaaatt ggccgcaaaa accctgcaaa agcatggctg
    14401 ccaaaaaatg atcatgatta caggaaatga tcattctgac tccccaacag gtcttagaca
    14461 gctaggcttt aattaccagc tcaaaaaagg cgctgatatt ataaaactgc caaatgatct
    14521 ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg gcgacaagaa ggcctgacgg
    14581 catttttgct tctgatgatt tgacagctat cctcatcatg aaggttgctg gccagcttgg
    14641 catagcaatt ccagataacc tgaagcttat cggctatgac ggtacggctt ttattgagca
    14701 ttatttccca cagctcacca ccatcaagca gccgatcaag gagattgcca gcttaaccgt
    14761 agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc aaggactatg tcttaccgat
    14821 caccctgctt cccggaggca gtctctaaga gcaatagctc ttcttctgtg attagcggct
    14881 ttcccctagc ttctccctta cttggggcac taaagtaaaa accaaagcac gaggtgggaa
    14941 accctagacc accaggatac acccagatag gtccccaaaa gaaagcttga taagcctgac
    15001 cacctaacaa aacctgcaca caaggaaagc ttcctcaagc tgtcctttgt acccttttcc
    15061 taacaatgcc accaaaaaca catgtaacag caagtga
//
LOCUS       DARYXZ010000051        14600 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYXZ010000051 DARYXZ010000000
VERSION     DARYXZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14600
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..255
                     /locus_tag="TV186_001623"
     CDS             <1..255
                     /locus_tag="TV186_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1533000.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
     gene            339..518
                     /locus_tag="TV186_001624"
     CDS             339..518
                     /locus_tag="TV186_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL1533001.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            537..1964
                     /locus_tag="TV186_001625"
     CDS             537..1964
                     /locus_tag="TV186_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1533002.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            2136..8966
                     /locus_tag="TV186_001626"
                     /pseudo
     CDS             2136..8966
                     /locus_tag="TV186_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            9476..11241
                     /locus_tag="TV186_001627"
                     /pseudo
     CDS             9476..11241
                     /locus_tag="TV186_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            11349..13259
                     /locus_tag="TV186_001628"
                     /pseudo
     CDS             11349..13259
                     /locus_tag="TV186_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            13303..13962
                     /locus_tag="TV186_001629"
     CDS             13303..13962
                     /locus_tag="TV186_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1533003.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
     gene            14112..14327
                     /locus_tag="TV186_001630"
     CDS             14112..14327
                     /locus_tag="TV186_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1533004.1"
                     /translation="MSKISYKKLFKKMIDLDMKNSELMEKAEVSRSTFYKMKNSENIT
                     TDVIVRICDSLNCGVNEIMELVDDENN"
     gene            14311..>14600
                     /locus_tag="TV186_001631"
     CDS             14311..>14600
                     /locus_tag="TV186_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HEL1533005.1"
                     /translation="MMKIIDYVIESTNKYIKQMPKEIRKKNGQFFTSKETALFMASLF
                     DLSSFSKEISILDPGAGSGILTAALIQRIIDTDKIEAIKITCYETNDDILEL"
BASE COUNT         5372 a         2104 c         3264 g         3860 t
ORIGIN      
        1 cagttcacaa gggcagggat tattgaaaac ttaatcttta agggatttgt agaaagagat
       61 aagaaaaacc ttatagccac acataaagga ataagccttg tagcgattgt agctgataac
      121 tttaagtcgg cagaaactac cgcaaaatgg gaaatggaat tatccgatat tgctcaaggg
      181 aaatcttcaa aggaagaatt tttagaagcg attgaaaatg agataaaaga agcggtttca
      241 acttatagta agtaagatga cactaatttc agagtagaaa aaatatctta aaagtgctat
      301 aatcttttgt aggaaaagta gggcgaaagg gattagtcat gaaagataca tttatagata
      361 ctgctaaagt tatgtcaaaa ggacaggtta ctattccaaa gaggattagg gaacttttga
      421 atttagaaaa tggagactat gttacttttg tagttaataa agatagagtt gaaattcaaa
      481 attccaatgt ttttatcgaa gaaaacatta agaaataaag gtggtgaaat aaacagatga
      541 cgatagatga aattaagaag ttaattcaag ccggagaaaa aatagatgtc gaatttaaag
      601 aatccaagaa cgctttaacc aaagatgtct ttgatacagt atgctctttc aacaatagaa
      661 atggcggaca tattttactt ggtgcaaatg ataaaagaga gatcgttggt gttagtgaag
      721 ataaagtaga taaagtgatt aaggaattta ctacggcaat caacaatccg caaaagatgt
      781 atccaccact ttatttgctg ccggaaactt ttgaaattga ggggaaacaa gttatttata
      841 taagagttcc tgaaggttat caggtatgca gacataacgg aagaatttgg gataggtctt
      901 atgaagggga catcaatatc acagatcatt cagagcttgt atataagcta tatgcaagaa
      961 aacaaggaag ctattttgtt aataaggtat atccgaatct tgatattgat tttcttgatg
     1021 cttctgtcat tgataaagct aagaaaatgg ctgttttccg aaataaaaat catgtttggg
     1081 aaaatatgag taatgaggag cttcttagaa gtgccaattt gatactgaca gatccggaaa
     1141 caaagcgtga aggaatcaca ttagctgcta ttttgttatt tggaaaagat aactctatta
     1201 tgtccgttct tccgcaacac aaaactgatg ctatattcag ggttgaaaat aaggatagat
     1261 atgatgatag agatgttgtc ataacaaatc tgattgacag ctatgacaga ctgatagaat
     1321 ttggacaaaa gcacttgaat gatttatttg tcttggacgg aattgtcaat gtcaatgcaa
     1381 gagacaggat actcagagaa atagtttcca atacgctggc tcatagagat tattcaagtg
     1441 gttttcctgc aaagatgatt attgacgatg agaggattac agttgaaaac agcaacttgg
     1501 ctcatgggat gggagcttta gatttacaga agtttgagcc atttcctaaa aatcctgcta
     1561 tatctaaagt ttttagagaa ataggtcttg cggatgaact tggttcagga atgcgaaata
     1621 cctacaaata cacacagctt tattcaggac aaaacccgct atttgaggag ggagatatat
     1681 tcagaacgat tattcctcta aagaagatag cgacacaaaa ggttggaggc gacaatgtcg
     1741 ctcacgatgt cgctcagggt gtcgctcacg atgtcgctca cgataagata gctctcgcag
     1801 agtttattaa agaaaaagtg agaagcaatg ataggattac aagaaaggct attgcagatg
     1861 aagctggagt tagcgtaaag actatcgaaa gagctataaa ggaaatagat aatctgaagt
     1921 atgtaggaag tggtaatagc ggacactggg aactgaatga ataaaattaa gttgcaaaac
     1981 aaagattttt ataaataaga gggtgctatg aataccataa aatgaggatt tgtagtagga
     2041 aatttaagtt gcagcaagtt gcaatacaca gaatcaaaag gtgattagag taaaatctaa
     2101 ccgccttttt tgtttggaaa aagaaggagg taaaaatgcg aataaatgat tttcataaca
     2161 ttttggagct tgtaaaacaa aatattttgc aaagtgaagc agaatacctg aagctcctaa
     2221 aggttgtcgg aaacaatcaa agatatgact ttagaagtca gttaagtatt tatgatagaa
     2281 attctgaagc gacagcctgt gccaagttcg actattggag ggaacgcttt aaccgtactg
     2341 ttatgagagg acaaaaaggt atccccattt tagaggacta cggcacatac aaaaaagtgg
     2401 catatatctt tgatataagt cagacggttt caagaaatag ggatgtcaat gaggtcaatc
     2461 tttggagatt tgataaagaa gctcataggg atgtcttaaa ggaaatgata aaaaacgagg
     2521 gctatgagga aagtgaaagc accttagaaa atatcttttc tttaagtaga ctctacggtg
     2581 atgaaaagat agacagcctt atgaatgagc ttagaatagc tgatgaggat agaatatctt
     2641 ttaccaagtt tgtgagggac tcagtgagtt atgcagtagc ttcaagattt aatgtagact
     2701 atcctatgga taatgagctt ctaaaggaaa actttgcaat gcttgatagc atttccctta
     2761 tgagtcttgg tgaaatcgta tcggatatta gtggaaagat tattgatgaa accattcaaa
     2821 aaagcaaaga gcttgagctt caaaaagaag ttttaagagg aaaagaagca ggatataata
     2881 ggattaaaga aaaaattgag aaaggagata atgatgtact tcgacgagat gatcaggaaa
     2941 gaaatgaaaa tgagcgagtt ctccgaaatg gagagtacgg acgagataat agagaaaatc
     3001 agggagaata cactaaacag cttggaggaa cagacggact tcataaggga gtatccgaat
     3061 ccgacctacg cagtaatgag gctggattac ctttcagaga gcgaggagca gagccacttc
     3121 gagatgttag tggatctata caaggagagg aagctaacag gacacctgat ggatattcag
     3181 aaacaggcga tagactttat gaggacagag aagccgaaat tgatggtagc ttggaagata
     3241 gaggacgaga acgatccgca gtatggggcg atgatttcag ctctgaagga aatgacaatc
     3301 aaggaagtat taaaaattta aaagataata ctgaggtaga gataagagaa gctgaaaagg
     3361 cttctttttc tttacccgaa aattcatatg gacagatgag acttaccatt ccattaactc
     3421 agagggatat agatactgtc cttattaacg gaggaaatca cgatggaagt agacttcctg
     3481 ttatcgctga gttttctaaa ggaaaaagta atgaagaatt aggagaatac ctaaaagata
     3541 tatttagagg cggtaatgga ttttacattg atgaaagaga agtatcttcc tggtattcgg
     3601 ataaaggcat tcatttagcc tacgggacat ctgcaagaga agatactacg caaattttaa
     3661 gctggagcga tgctgcaaag aggataaatg agcttcttga taatggtgag tttgctacaa
     3721 atgtagagat ttctgaggct cctgattatg aaagagataa gatttcagag tccttatggt
     3781 atctaatgca tgatttaagc gaagaaggac aaggatattt tgaactattg aaaacaagtg
     3841 gaagaggctt tccggaagaa acaaaaagat tgtctgaagc attaaaaaat cccgactacc
     3901 taaaggaaac gatcaaagaa tacagcaggt ttttagaagg atacaaagaa aacagaaatg
     3961 tattaaggtt tcactatcac aaggtagata gcctttgtca gaggttacag gaacttgagc
     4021 tgtcacgaaa ggaatatagt accaatctaa cagagcttcc gaaggtaaag tccttcatta
     4081 cagaagatga agtccttgaa agtctttcaa gaggaagtgg cgtcgataga ggaaaagagc
     4141 gaattacaaa gtttttcaaa gaaaatcata ccttgcagga aaaagctaat ttcctaaaag
     4201 acgaatatgg cataggtggt agaagtcatg cagtatcggg ggcaatggga agtgatgaat
     4261 ggcatgatgc aaaggggctt aaattacaga agaataattg taatgatgtt tttcttactt
     4321 ggtcaagtgt ggcaaagcgt atagaggagc tgctttctaa aaatctgtat gaagaaaaga
     4381 aaatagaaag taagtcagag gtagaagaat caaaagagct acaatattat tctaaagata
     4441 atcctgaaaa cttaatgact gatgaaatgc ttgaaagagt gcctgagctt tacgcacagg
     4501 aagatgtagc tttagcggat aaagaggttc atgcagcata tattattcct ttccgttcta
     4561 actggacttg gtatatgacg gaatatgata gggaaagcgg tgatgccttt ggacttgtgt
     4621 taggatttga acctgaatgg ggatatttca atcttgaaga attgaaagaa ttaaatgctc
     4681 aaaggcttat tttagaggat tttccaaaga cttttagaga gcttaaagat acagaacttg
     4741 caaagcagat ggatgaacag gaacttcaat cagtctttaa cggagaactt agctttgaag
     4801 ataaagaaga acttgaaata tctgaagaag tggaagaaag agtagctgca acacctgttc
     4861 aggaaacact atttgattat ctgaaggaga aggaagaagt agagcttaac gaagaaaaga
     4921 aaagtatttc agatgaattt gcagttaaag agggcgatac cgtctatttt aatcatgaag
     4981 aatatactgt aagggaaatt gctgaaaata aaatcacaga aagatatgac ttatggcttg
     5041 atccgggaag aagtggaaac catcaaatcc ctattgtagc ctttacagat aatgaagatt
     5101 tattaagaca agtaagccct gaaagacctg cgtttatcgt tggagatgaa attaaataca
     5161 aggataaaga ctataccatc acacgctttg acgatatggg aaataatcta aagacggtaa
     5221 cggttaagga taataccgaa tatcttggcg gtatgataac aggctcagat gtaattcctt
     5281 atcgtcttga aagcgatctt gagagggtat ttgaaaatct gacatataaa aagcctgaaa
     5341 ctattgctaa agaaagtgaa ataaagaaag cagaagctca taacttcaag attacggaag
     5401 aaacattacc tgacaagtta tctccaagtg aaaggctaaa taataacctt gaagccatct
     5461 ctatgctgag tcgcatcgaa agtggacaaa gagagtttga cagtacagct caggaagttt
     5521 tagcaaggta tgtaggctgg ggtggacttg ctgatgtatt cgatgaagaa aaaggcggac
     5581 agtggaaaga agcgaggagc tttctaaagg aaaacttatc tcaggcagaa tatgaagctg
     5641 caagagaatc taccctaacg agcttttaca caccgaaaac tgttattgac ggcgtatata
     5701 agacactttc cgatatggga tttaagagcg gaaatatcct tgagccatca atgggcatcg
     5761 gaaactttat aggaaatctt cctgatgaaa tgaacaagtc aaagttttat ggtgtagagc
     5821 ttgacagtat aagcggtagg attggaaaac ttttataccc tgaaagtgat atacagatta
     5881 aaggacttga agaaacttct ttttccaata acttttttga tgttgcaatc ggcaatgttc
     5941 cctttggaga atacaaagta aatgacaggg aatacaatcg taataacttc cttattcatg
     6001 actatttctt tgccaagtcc attgataagg ttagaaacgg cggggttatc gcctttatta
     6061 catcaagtgg aacaatggat aaaaaggatg aaagtgtaag acgctatctt gcagcaagag
     6121 cagagttttt aggagctatc agacttccta atgacacctt taagggtact gccggcacag
     6181 aagtaacctc agatattatc ttcttaaaga aaagagatag cgtattagag cgtgatgaag
     6241 attggataca ccttgcggaa gatgaaaacg gtcttgtata taacaaatac tttgttgatc
     6301 atcctgaaca ggtacttggc tcaatgcgtg aagtaagcgg aagatttgga aaaactctaa
     6361 cttgtgaacc gatatcttat ttaggcacag agctaaatat ggcttcatta aaggatcgta
     6421 tcgagattgc aggagaaaga atttcaaaag atgccaagta tgaagaaata gagcttttag
     6481 atgatgaaat cacttcaatc cctgcaacgg atgatgttaa gaacttttcc tataccatta
     6541 ttgatgatga agtctattac agagaaaact cactgtttat caaaaaggaa gtaaccgata
     6601 aaaacaaaga aaaaatcaag gattatcttg agctgaatgc tgccttaaaa aatgtgattt
     6661 acaagcagaa agaaggtttt agtgaggaag aaatcaaggc ttcacaggaa aaactaaatg
     6721 aagtctatga ccgtttttct aataagcatg gctttgtaaa taatttaagc aatacaagag
     6781 ctttaaaaga ggatagcaac ttcccgcttg tttcctccat tgaaatcctt gatgaagaaa
     6841 actttaaggc aaagggagat attttctcca aaagaactat tacaaaggct aaagtcatag
     6901 atcatgtgga tacttcttta gaagcccttg tcttatcggt atctgaaaaa ggatatgtgg
     6961 actttgacta tatggaaggt cttacaggaa aagacagacc gactttgatt gaggagcttc
     7021 gaggggaaat ctacttaaat attagggaag aacaaaactt ttatagacct ctatccttta
     7081 accccgaaga tggagatttg ccttttgcct gtgccaatgg cagtaattcc tacaaatacg
     7141 gctatgtaac aaaggatgaa tatttaagtg ggaatatcag ggacaagatt gccatagtag
     7201 atagctatct atcaaagctc agacagacgg aaagagagtt acctcatctt ggctatgcag
     7261 aagatggtaa agaaaaagag ctgattagct atgagatgaa tcgtttggaa taccaaaagg
     7321 ctgagcttac aaaagttcta ccaaaggagc ttgaagcaag tgagataagt gttcgtcttg
     7381 gtgcgacttg gataccgatt aaagatattg aaaaatttat ttttgaaacg ctgaaaactc
     7441 cgggatatgc aagatgggat attaaggtta agttttcaaa cctgacaagt gagtggaata
     7501 tagaaggtaa aagtagggat agaggaaatg acctcgctga aatgacttac ggtacatcaa
     7561 gggtaaatgc ctataagctg attgaagatg ccttaaacct gaaagaaaca aaggtatttg
     7621 accagattgt aaatccggac ggctctaaaa cttctgtact aaataaaaaa gaaaccatgc
     7681 ttgcagggca aaagcaggaa ctactaaaag aagaatttaa gaactggata tttaatgatc
     7741 aggagagaag aaaccgtctt gtaaaactgt ataatgagcg ttttaactct atccgaaaca
     7801 gagaatatga cggaagtaat ctttcctttg agggaatgaa tactaaaata gatttaagac
     7861 ctcatcagag aaatgccata gcaagaagtc tttatggagg caacaccctg cttgctcatg
     7921 tggtgggcag tggaaagacc tttgaaatgg tggcttccgc aatggaaagt aaaagacttg
     7981 gaatgtgtag taagtccttg tttgttgtac ccaatcactt aacaggacaa atcggtcgtg
     8041 agtttatgca gctatatccg tcggcaaata tcatggtggc agataagaaa gattttgagc
     8101 cgaagaaccg taagcgtttt atcggtcgaa ttgccacagg agaatacgat gccgttgtta
     8161 tcgggcatac gcagtttgaa aaaattccta tgtctaagga atatcaggag aagcatatcc
     8221 aagatcagat tgatgaaatc gtaaactatg tagaagaata caagcatgac agaaatcaga
     8281 actttacagt aaaacagctt gaaaagacaa agaaaaaact ggaaacaagg cttgagaaat
     8341 taaatgacga ttttaagaaa gatgatgtca ttacctttga ggaattagga gttgataagc
     8401 tctttgttga tgaagcacac aactacaaaa atctctatct ttatacaaaa atgcgtaatg
     8461 ttgcaggaat cggtcaaagt gaagccttta agtcctccga tatgtttatg aagtgtcgct
     8521 atatggatga aatgacaaac ggaaaaggca ttgtctttgc aacgggaacg cctgtatcaa
     8581 actccatgac tgagctttac actatgcagc gttatcttca gtatgagagc ttaaagaaaa
     8641 ataatctgga gcattttgat agctgggctt ctacttttgg ggaaacgcag tctgcttttg
     8701 agctttctcc ggagggaaca ggatacagag taaagacaag attttccaag ttctataact
     8761 tgcctgaact aatgtctatg tttaaggaag tcgctgacat tcaaacagcg gatatgttaa
     8821 atcttccaac acctgaggca cattatgaag taattaagac cttgccaagt gaggagcaaa
     8881 aggaaattct aaagagcctt tctgaaagag cagatgatgt gagaaatagg gtggtagagc
     8941 ctgacaaaga taatatgcta aaaattgtgc gctgttaagc gtaaaaatgt atctccctca
     9001 cagagggata ttattgaaag taaataatag gaacaactaa ctaacctagc ggggaaaccc
     9061 aaaggggaca atagcatgtt agtaaagcgg ataaggagtg agttacaacg ctttgatgtg
     9121 ccgcaagttc cgtaacctat ggttaaggct aaactgcttg aacctcaatt ctgactaggt
     9181 gcaaagcatc gcccatcgga aagtaactga gaccgatgtt actgtatatt cgttgttgtg
     9241 attttggacg aataactttc tacagtaaaa gagcatacga taagtatgaa taaaggaatg
     9301 agtgaggaac ctaagggtta ctagaacgta catttttaac gaatagcagg attgcctaag
     9361 aggggggacc cttatggtaa cggagtcacc gtagtagtcc gagcaaggga aatccttgta
     9421 catggcgaag ggtgacaggt aatttcgatt agttagaaag gattaggtgc gtgggatgcg
     9481 tacagccaaa actattttaa cggtcattca tgaacgtgga aaacaagata aaccactcga
     9541 aagggtttat aagttactat ttaatcgtga actctatctg atagcctatg caaagttata
     9601 cccgaataat ggagcaatga caaagggtgt tacagaggaa acgattgatg gaatgtctat
     9661 tcaaaaaata gatatgatta ttgaacaatt aagacaagaa acctattact ggagaccagc
     9721 taggagagag tacattccta aaaagaatgg aaaacaccgt cctttgggaa taccagtatg
     9781 gagtgataaa cttcttcagg aagtgattcg catgatatta gaagcctatt atgagccaca
     9841 atttagtgaa cattctcatg gttttagacc aaaaagaggg tgtcatacag ctttacaaga
     9901 aattcagact tggaaaggga cacgttggtt catagaagga gatatctcta gttattttga
     9961 cacgattgac cacgatgtat taatcactat gttgtctaga caaattcagg atggtcggtt
    10021 tattaggctt atcaaaaata tgcttgaggc aggatatctt gatgattgga agtttcacaa
    10081 gactattagt ggaacaccgc aaggtggagt tattagtcct ttattagcta atatctattt
    10141 acatcaattt gataagtggg tcggtgaaga gctgatacct caatatacaa gaggtaaaaa
    10201 gcagaaagca aactcagcct ataatcgttt gagtagaaga attaaatgct atcaggataa
    10261 aggagattat aaaaaagctc atcagttaat tgttgagaga agaaatctcc cttcagttga
    10321 tacttatgat accagctatc ggagattaag atatgttcgg tatgcggatg actttattct
    10381 aggctttaca ggttcaaaag ctgaggcaaa ggctataaag aagcaaattg gagacttttt
    10441 aaatactaag ttatctttgg aactttctca agaaaagact ttgattaccc atgcgactgg
    10501 agaatcagct aaatttctgg gatatgagat aaaagcacaa cgtgtcaatg attatattga
    10561 taacaaaggg agacagagtg ccaatggtgt tatcgcatta tttgtacctg catcagttat
    10621 tgaaagcaaa tgccgccaat acatgaaaaa tggtaaagct attcatcgta ataacttatt
    10681 gcatgatgat gactttagta tcgttcaaac ttaccaacaa gaatatagag ggctagttca
    10741 atattatata ttggcacaaa atttgtcatg gttctcaaaa gtctattggt atatggaaac
    10801 atcactcctt aaaacattag catttaaaca tgagtcatcc attaataaaa tgttagctaa
    10861 atataagact accacaacta gcacgaatgg ccgaacggtg ccgtgtttac aggtagttgt
    10921 gtctcgagaa gataaacctc ctctagttgc aacgtggggt ggcataaaaa gaaagctgta
    10981 atagaagatg ctccgtatca agtttatggt ggtcgaacag agcttatcaa gcgattactc
    11041 gcaaataagt gtgagctatg tggaagtgag gagaacatag aggtacatca tatcagaaaa
    11101 ttagcagact tgaacaaaca caatgggaaa ttagttccaa agtggaaaga aatcatgtca
    11161 gcaagacgtc gaaaaatgct agtgacttgt cgggattgtc accatgcaat acataatggt
    11221 tcaataaata cacgtttatg aaatgaaatt actggagagc cggatgatgc gaaagtatca
    11281 tgtccggttc ggtgggggga taatggaaaa ggggtcgcaa tgactacctc gctagtatcc
    11341 taccctacac taatgatggt aaaaaacttg ccttagatca gcgtttaatt aatcctctgc
    11401 tacctgacaa tcctgacagt aaggtcaatg tctgtgtgaa aaatgtcttt agtatatggg
    11461 ataagacaaa agaagataag tcaacacagc tactattttc tgatatgtct acaccaaaag
    11521 gcgatggaga atttaacatc tatgatgata ttagagaaaa acttgtagca atgggaatac
    11581 caaaagaaga aatcgccttt atccacgaag cgaattccga taaacaaaag gacgaactct
    11641 ttgcaaaggt gcgtaaagga gatgtgagga tattacttgg ttctactcag aaaatgggag
    11701 ccggcacgaa tgtacaaaac aaactgattg cccttcatga tttggatgtt ccttggcgtc
    11761 ctgccgattt agagcagcgt gcgggcagaa ttgtaagaca gggcaatgaa aacaaggaag
    11821 taaatatcta tcgttatgtt acggagaaca cctttgatgc gtatttgtgg cagacaatag
    11881 agaataagca gaagttcatt tctcagatta tgacaagtaa aacacctgtc agagtggcag
    11941 aagatgtgga tgaaagttca cttaactatg cagaaattaa agcccttgcc acaggtgatc
    12001 cgaagattaa agaaaagatg gatttggata atgaggttac gaaacttaaa atgcttgaag
    12061 caaactataa gtccaaccgt tacagattag aggataaagt ggcgaaaaac tatcctgaag
    12121 aaatcgcaag aactgaaaag ctcatagaag ctgtcaagaa agatatatct gatgtagagc
    12181 ctaaagcgga cggagaggaa aagtttactt ctattactat cgcaggagca aagattaccg
    12241 ataagaaatt agcaggagaa agattgcttg aagctatttc aaaggttaaa atcaatgaaa
    12301 gtaaggtaat cggtaagtac agaaatatgg acttggaagc aagttataac ttctttacta
    12361 attctcataa tttcagctta aacggtgttg caaagcattc aggagagctt ggcacaagtg
    12421 ctgacggtaa tattacaaga cttgataacg ctcttgagaa aatgcctgag aaattaaaga
    12481 ggcttgaaga aaagctcata agcaccaaag agcagcttga aaatgccaaa gaggaattaa
    12541 aaaagccgtt tgaaaaagct gatgaattaa agagtaaggt gcttcgcttg gctgaactaa
    12601 ataagctact tgatatgggt gatgtggaag aaaagagaaa tgataatccc cttgtagaag
    12661 atgttaaaag ggcaattatt gatttctgta acagagaata tgaagaaaat catagctacg
    12721 atgagtttga tgctctatat cctgacttaa agcatatagg aattgcctat accaacacgc
    12781 cggatgaaag acacagcatt caatatgagc ttaatttaga ggataagata tggacacagt
    12841 atattgatga tatatctata aaaactgaga gctttgacta tgagaacaaa ggagagaatg
    12901 aaactctaag aaatatgaaa aatgagattg agctatcctc ttttgaagat ctggtttatg
    12961 tggattcaga agatttgaaa gcagcaacgg gacttgatat tgatgacgaa ggtaacttct
    13021 atgatccgct ttctaaagac cttgataatg acggaattac tgaccgttac gataatgact
    13081 ttaaggacag cgactatttt gaatcaacat atgatgtgga ggataatttt catagcaaag
    13141 aagaaagttc acaaaaatca gaggataagc catctatttt aggacagata agagcctatc
    13201 aggaagaaag taaaacagaa gaaaaacaaa ctacaaaaga acaggaattt ttaagataag
    13261 gggagggtaa cctccctttt actatgaaag gagataaaaa acatggatta caaaacaatg
    13321 agaaatcaaa tagaagatat ggcaaatgat aaccacaagg actttgtaaa agcgattata
    13381 agcgtggaga aaggtatcaa tgatgaaagt gctttggaca agctctatga cgcttatatg
    13441 gacaatgaca gtctgaattt actgcatgag gaatttgact acatgattga agatttacga
    13501 gaacaggggc aaataaaaga cctgccctat gttcaggaag agaaagataa tcttatcaat
    13561 atcgttggaa atattgtagg aaaggttgat gtagctgaaa gagaaaacaa gaatggagaa
    13621 gcctttaagg tggcaaattt ctctgttgta tctaaagatg atgagggaaa taaggtttat
    13681 cataattgct ccgcttatgg agaaaagagt gatattccaa aagactttaa gcagggagat
    13741 tttgtaaagc tctttggaca aatcagaact tccattgatg ataatggcaa ggagcatagc
    13801 aatgtaagga tactttcttc aaagctctta aaggcaaagg aacaaatgaa aggacaagaa
    13861 gaaaagaaag aatctgttct tggagctatc aagaaatatc agtctgaaga taaggaaaaa
    13921 ccaaaagaaa agagagacgc aagcaaagaa gctgagagat aaatatatgg tcggtgtggt
    13981 cttaggactg caccgactct tttttgtcta tctaaatgtc gtgtgtttgt gtaaaaggaa
    14041 gtttgtagtg aaaaaagtga ataaatatga tataatgata aaaacaaaat catatgcatg
    14101 ggaggacaat cgtgtcgaaa ataagttata aaaagctatt taaaaaaatg atagatttag
    14161 atatgaaaaa ttctgagcta atggaaaaag cagaagttag ccggagtact ttttataaaa
    14221 tgaagaacag tgagaatatt actactgatg tgattgtcag aatatgtgat agtttgaact
    14281 gtggtgtaaa tgaaattatg gagttggtgg atgatgaaaa taattgatta tgtaattgaa
    14341 tctacaaata aatatattaa acagatgcca aaagaaattc gcaagaaaaa tgggcaattt
    14401 ttcacaagta aagaaacagc tcttttcatg gcatcattat ttgatttatc atcattttca
    14461 aaagaaattt ctatactcga tccgggagcg ggttcaggaa tacttacggc agctcttatt
    14521 caaagaatta ttgatactga taagattgaa gccataaaaa ttacttgtta tgaaaccaat
    14581 gatgatattt tagagctgtt
//
LOCUS       DARYXZ010000052        14535 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYXZ010000052 DARYXZ010000000
VERSION     DARYXZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14535
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(81..1361)
                     /locus_tag="TV186_001632"
     CDS             complement(81..1361)
                     /locus_tag="TV186_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1533006.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TV186_001633"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TV186_001633"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL1533007.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTRIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPAARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TV186_001634"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TV186_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1533008.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TV186_001635"
     CDS             6342..6845
                     /locus_tag="TV186_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL1533009.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TV186_001636"
     CDS             7344..8537
                     /locus_tag="TV186_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1533010.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TV186_001637"
     CDS             complement(8736..9200)
                     /locus_tag="TV186_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533011.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TV186_001638"
     CDS             9468..10316
                     /locus_tag="TV186_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL1533012.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TV186_001639"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TV186_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL1533013.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TV186_001640"
     CDS             11592..12071
                     /locus_tag="TV186_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL1533014.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..12433
                     /locus_tag="TV186_001641"
     CDS             12068..12433
                     /locus_tag="TV186_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEL1533015.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     GALGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLLCLTIVGIPFARQ
                     SLKLAKISLFPFGAIIYDI"
     gene            12452..13096
                     /locus_tag="TV186_001642"
     CDS             12452..13096
                     /locus_tag="TV186_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1533016.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
     gene            complement(13527..13694)
                     /locus_tag="TV186_001643"
                     /pseudo
     CDS             complement(13527..13694)
                     /locus_tag="TV186_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            complement(13932..>14535)
                     /locus_tag="TV186_001644"
     CDS             complement(13932..>14535)
                     /locus_tag="TV186_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1533017.1"
                     /translation="DVLNYNKIRDVDIFNRILSFAIENIGSTFSANSIKKYLKNESRG
                     VSVDTILNYLEYCNRAFILKKVQRFDTVGKKKLKVDEKYYLTDHGFRQARGYSNTKDI
                     ERTLENIVYIELVSRGYRVEIGKVKDLEIDFIASKDNERLYYQVSYLMETEETRKREF
                     GVYDFVRDNYPKFVLSMDKVDFSQNGIIHKNVIDFLLESK"
BASE COUNT         4373 a         3164 c         2707 g         4291 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcag cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat tcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcgctttggg tctttttcct tttggaaaag ccatcgaaat
    12241 tggccaagga gcaggcagcc tgctgctcaa tatcatctgg attgtctgct gtggctggag
    12301 cttagcgatc atgcatttga cttctgccct tctcttgtgc ctcacgattg ttggcattcc
    12361 atttgcccgg caatctctaa aattggccaa gattagcctc tttccttttg gagccatcat
    12421 ttatgacatt taattaggaa gcaaaagact tatgaaattg tattttgtca gacatggtaa
    12481 aaccttgtgg aacctagagg gccgttttca gggagctaac ggagattcgc ccttgcttga
    12541 aagctctaag gacgatttgc gccagctagc aagagagctg tgggacattt cttttgatgc
    12601 gatctactcc agcgacctaa aaagagctgt tgatactgct cgcattattg tggacgaagc
    12661 taactgcaag actgatatta gttataccaa gcagctgaga gaatggaacc taggcaccct
    12721 ggaaggaacc aaaatagcaa ctgtatccgc catctacccc agtcagatgt cagcctttta
    12781 tcacaattta gccaaattca agcccagtca atttaaggct gaatcccttt atgaaagcac
    12841 acaaaggctt tatcagctca ttaaaagttt ggaagataag gcctatcagc aggttttaat
    12901 ggtaggacat ggcgcccatt tgacagcttc tattcgtgct cttttaggct ttgagccagg
    12961 tatgcttcgg gcacagggag gactggataa tgccagccta accgttatag aaaccttgga
    13021 tttcaaacac tttcattgtc taaggtggaa tgatacatca tttttacaaa aaaagactac
    13081 tagattaaca ccctagtagc tcttaagcac aaagctccaa gacagctaaa ctgtactcca
    13141 ttggttagag aacacatctc attttttgag ggacgcttta ttagctgtag gaagttatga
    13201 aaagctaaat acacgagagg actaaattgg acaagctcaa aagtttgaca atgtatttca
    13261 aaaaaggatt gaattctgta tcgaacagga ctcagtcctt tttatcattt atcaagccga
    13321 ccaaggcttt caaccacgac aaacgcgcaa aacagttatt tcctgatgat agtagagact
    13381 acagcagata ttttcaatga ttttcttgta gtaacatcta tacaaaacaa tacagctcat
    13441 tgaaatatag gaacattaaa attcagaaag atttcttttc ttgctaaaaa tctttcatcc
    13501 atttcaaact ggttttcatt tgtcctctcc tttttcagtt ctgctttttc tccataagct
    13561 gcacagttga tgtactcctt gcctttaccg tacttcttta caaatgtaaa atttacaact
    13621 tatacttctt ctccttctct ttcaaaactt gagtaaattg attctgctac taaatttgcg
    13681 ttaatattaa tcatttttta tccataattt ttctcctttt ttaatttaaa attcccatta
    13741 aaaaagcgac tggacttttt ccaatcgctg atacttctac tattttattt ttatttcggt
    13801 agaacttcta atccttatca tctatatcct cctttttaaa cacaaaaaag acggtagatt
    13861 ttttcttttt ccattgtctc ttataactta tatttaattt ttgaatagta tgcaaacatt
    13921 taaggaaaca actacttgct ttccaataaa aagtcaatca catttttgtg aataattcca
    13981 ttttgactaa aatccacttt atccatggat aagacaaatt taggataatt atctctaaca
    14041 aaatcataca caccaaactc tcgttttctt gtttcttctg tttccatcaa ataagaaacc
    14101 tgataatata acctttcatt atccttactt gcaataaaat caatttccaa gtcttttact
    14161 ttgccgattt caactctata tcctcttgaa acaagttcaa tataaacgat attttccaat
    14221 gttctttcaa tatcctttgt attggagtat cctcttgcct gcctaaatcc atgatctgta
    14281 agataatatt tttcatcaac ctttaacttc ttttttccta cagtatcaaa tctttgtact
    14341 ttttttagta tgaaagctct attacaatac tctaaataat ttaaaattgt atcaacagat
    14401 actcctctgc tctcattttt caaatacttt tttatactgt tggcggaaaa agtagatccg
    14461 atattttcaa tagcaaaaga taatatcctg ttaaatatat ctacgtctcg tatcttatta
    14521 taattaagca catct
//
LOCUS       DARYXZ010000053        13930 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYXZ010000053 DARYXZ010000000
VERSION     DARYXZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13930
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            102..1115
                     /gene="pfkA"
                     /locus_tag="TV186_001645"
     CDS             102..1115
                     /gene="pfkA"
                     /locus_tag="TV186_001645"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL1533018.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            1177..2679
                     /gene="pyk"
                     /locus_tag="TV186_001646"
     CDS             1177..2679
                     /gene="pyk"
                     /locus_tag="TV186_001646"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL1533019.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            2808..3365
                     /gene="lepB"
                     /locus_tag="TV186_001647"
     CDS             2808..3365
                     /gene="lepB"
                     /locus_tag="TV186_001647"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1533020.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            3542..5353
                     /gene="glmS"
                     /locus_tag="TV186_001648"
     CDS             3542..5353
                     /gene="glmS"
                     /locus_tag="TV186_001648"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL1533021.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            5537..5872
                     /locus_tag="TV186_001649"
     CDS             5537..5872
                     /locus_tag="TV186_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL1533022.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            5979..6620
                     /locus_tag="TV186_001650"
     CDS             5979..6620
                     /locus_tag="TV186_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1533023.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            6630..7259
                     /locus_tag="TV186_001651"
     CDS             6630..7259
                     /locus_tag="TV186_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1533024.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            7276..8112
                     /locus_tag="TV186_001652"
     CDS             7276..8112
                     /locus_tag="TV186_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1533025.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(8208..9446)
                     /locus_tag="TV186_001653"
     CDS             complement(8208..9446)
                     /locus_tag="TV186_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL1533026.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(9549..10883)
                     /locus_tag="TV186_001654"
     CDS             complement(9549..10883)
                     /locus_tag="TV186_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL1533027.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(11012..11098)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            11363..13654
                     /gene="pcrA"
                     /locus_tag="TV186_001655"
     CDS             11363..13654
                     /gene="pcrA"
                     /locus_tag="TV186_001655"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL1533028.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
BASE COUNT         4069 a         2601 c         3254 g         4006 t
ORIGIN      
        1 gttgaaaacg gtttttcgat aaaaatagcg aattagtgaa gtaatttgca aacgaatgtg
       61 ctataataaa aacgttaaat taattaaagg agtaccaaaa aatgaaacgt attgctgttt
      121 taaccagtgg tggtgacgcc cctggtatga atgctgctat tcgtgcagtt gttcgtaaag
      181 caatttcaga aggaatggaa gtctatggta ttaaccgcgg ctatgctggt atggttgatg
      241 gtgatatctt tccactaggc tcaaaagagg ttggtgataa gatttctcgc ggcgggacct
      301 tcctttattc agctcgctac ccagagtttg ctcagcttga ggggcaattg gctggtattg
      361 agcagctaaa aaagcatggc attgaagggg tagttgtcat tggtggtgat ggttcttacc
      421 atggtgcgat gcgcttgact gagcatggct tccctgcagt aggtatccca gggacgattg
      481 ataacgatat tgctggaaca gactatacta tcggatttga cactgcggtc aatactgcgg
      541 tagaggctat tgataagctt cgcgatacct catcaagtca tggacggacc tttgttgttg
      601 aagtgatggg acgcaatgca ggtgatatcg cactttgggc aggtattgca agtggagcag
      661 atcaaatcat cgttcctgaa gaggaatttg acattcataa agtggtctca acaattaaag
      721 acgattttga aaatagagga aaaaatcacc atattatcgt tttagctgag ggtgttatga
      781 gtggcgaggc ctttgcgcag cagctaaaag aagctggaga tgaaagtgac cttcgtgtga
      841 caaaccttgg tcatatcctt cgcggtggct ctccaactgc gcgtgatcgt gtgattgcgt
      901 catggatggg agcgcacgct gttgagttgc tcaaggaagg caaaggtggc ttggctgttg
      961 gtattcataa tgaagagctt gttgaaagtc cgattcttgg aagtgcagag gacggtgcct
     1021 tgttcagcct tactgatgag ggtaacattg ttgttaataa cccgcacaag gctcgcttag
     1081 actatgctgc tttgaaccgt tcattagcac aataggataa gtaagatctg gtaatctttg
     1141 ttaatcaact aaaaaataag ggagtttcat aataaaatga ataaacgtgt aaaaattgtt
     1201 gcaacacttg gtcctgcggt tgaaattcgc ggtggtaaaa aatatggtga ggacggctat
     1261 tgggctggtc agttggacgt tgaacaatca gctaaaaaga tcgctgaatt gattgaagca
     1321 ggtgctaatg ttttccgctt taacttctca catggtgacc acaaagagca gggtgaccgt
     1381 atggctactg ttcgtcttgc tgaaaagctg gcacgtcaaa aggttggttt ccttttggat
     1441 acaaaaggac cagaaatgcg tacagaattg tttgctgacg atgccaaaga atatagctat
     1501 gtgactggtg agcgtattcg tgttgcgaca gcacaaggca ttcaatcaac tcgtgatatg
     1561 attgccttga atgtagctgg tgctcttgat atttatgatg aggttgaggt tggccacact
     1621 attcttattg acgatggaaa gcttggctta aaggttatcg agaaggacat tgcaaagcgt
     1681 gagttcatcg ttgaggttga aaatgatggc atcattgcaa agcaaaaggg tgttaatatc
     1741 cctaatacca agattccttt cccagcctta gcagaacgtg ataatgctga tattcgtttt
     1801 ggtcttgagc aaggtcttaa ctttattgct atttcatttg ttcgtactgc caaggacgtt
     1861 gaagaggttc gtgagatttg tcgtgaaaca ggcaatgagc atgttcaatt atttgctaaa
     1921 atcgaaaacc aacaaggtat tgataacctt gatgaaatca tcgaagctgc agatggtatc
     1981 atgattgctc gtggtgatat ggggattgag gtgccatttg aaatggttcc agtcttccaa
     2041 aaaatgatta tcaccaaggt aaatgcagca ggtaaagcag tcatcaccgc aactaacatg
     2101 cttgaaacaa tgactgaaaa accacgtgca actcgttcag aggtatctga cgttttcaac
     2161 gcggttattg acggtacaga tgcgacaatg ctttctggtg aatcagcaaa tggtaaatac
     2221 cctgttgaag cagttcgtac aatggctaca attgataaaa atgcacaaac tcttcttaat
     2281 gagtatggtc gtttagattc atctgccttc ccacgtacca ataaaactga cgtgattgct
     2341 tcagctgtta aagatgcaac acactcaatg gatatcaagc ttgttgtgac catcactgaa
     2401 acaggaaaca cagctcgtgc catttctaag ttccgtcctg atgctgacat cttggctgtg
     2461 acctttgatg aaaaggttca acgtgccttg atgattaact ggggtgtgat tccagtgctt
     2521 gctgaaagac cagcatcaac agatgatatg tttgaggtag cagagcgtgt agctcttgag
     2581 actggtttgg tgcaatcagg agataatatc gttattgttg caggtgtgcc agttggtaca
     2641 ggtggtacaa atacaatgcg tgttcgcact gtaaaataat agctttccat aagctttagc
     2701 tattttgctc tatcagataa tttaaggcaa acaatgatac ttaaaaattg tttgcttttt
     2761 ttattagtca tatcatgtta taatgagact atagactagg agttattatg gtaaagcgag
     2821 attttataag aaatatattg ttgttattga ttcttattgt gggagctgtc cttcttagaa
     2881 tatttgtttt ttcgacctat cgagtcacgt cagaggcttc aaatgcctat ttgaataagg
     2941 gcgatttaat caccattaag aaaaatattg agcctaaata taaggatttt gtggtttata
     3001 cggttgacaa aaaggattat gtgagccggg ttgtagcagt agcaggtgat cgtgttacct
     3061 atatggacga tattttttac ctgaacaata tggttgaatc ccaatcctac cttgagagta
     3121 tgaaggcaaa gtatctcaat catgccccta ttggtacgct ttatacggag gattttacga
     3181 tttcgacggt tacttctgga aaatacgata gcattcccaa ggggaaatac cttttgctaa
     3241 atgataacag aaaaaaccat catgatagcc gtcagtttgg cttaattgac gtgtcacaaa
     3301 ttaagggatt agtaacattt agagtgcttc ctttgaaaga ctttggattt gtagaggtag
     3361 agtagcttta aggctgctct attttgtttc tcaaaatatg actataccaa ttttcttgtt
     3421 gacaagattt ttctgaagtt atatactcta aatataacgt tttagtcggt ttatatctga
     3481 ctataccaat tatattgatc attaaagaaa gtagtaagct agcttactga ggtgttaagt
     3541 tatgtgtgga attgttggag ttgtaggtag tcgtaatgcg actgacatct tgatgcaggg
     3601 attggaaaaa ttagagtatc gtggttatga ttcagctggt atttttgtgt cagatggcag
     3661 gacgtccaat ttggtaaaat ctgttggacg cattgcagat ttacgctcta agattggcat
     3721 tgatgttgtt ggaacgaccg gtattggtca tacacgttgg gcaacgcatg gtcaagcaac
     3781 agaggaaaat gctcaccctc atacctctca gacaggtcgc tttgttcttg ttcataatgg
     3841 tgtgattgaa aattacctcc agatgaagga gcagtacctt gctggacaca cgtttaaagg
     3901 acaaacagac accgaaattg cagttcattt gattggagca tttgttgaag aaggctgttc
     3961 agtcttagag gcttttaaaa aggctttatc aatcattgaa ggctcctatg cctttgcttt
     4021 gattgataca gaggatatgg atacgatcta tgtcgctaag aataaatccc cattgctgat
     4081 tggccttggt gagggctata acatggtttg ttcagacgct atggccatga ttcgtgaaac
     4141 cagcgaattt atggaaatcc atgacaagga gctggttatc ctgacaaagg attcagcaag
     4201 ggtgacagat tatgctggca atccgattga tcgtcagtca tatacagcag agcttgatct
     4261 ttcagatatt ggcaagggga cctatccatt ttatatgcta aaggaaattg acgagcagcc
     4321 aacagtgatg cgtcgcttga tttcaaccta tgcagacgcc aagggacaga tgatgattga
     4381 tccagctatc ataaggtctg tccaagaggc tgatcgtatc tatattcttg cagctgggac
     4441 ctcttatcat gctggctttg cttctaagtc aatgctggag catttgactg atacacctgt
     4501 tgaattaggg gttgcttctg agtggggcta caatatgccg ctattgagca aaaagccaat
     4561 gtttatcctc ttgagccagt ccggtgagac agcagatagc cgtcaggttt tggtcaaggc
     4621 aaatgagatg gggattccaa gcctaacagt gacaaatgtt cctggctcaa ccctatcacg
     4681 tgaagcaacc tacactatgc tgctccatgc aggtccagaa attgcagttg catcaactaa
     4741 agcctacaca gcacaggtcg ctgcacttgc ctttctagct aaggcagttg gtgaggctaa
     4801 tggcaagaag gaagctatta gctttgattt ggttcatgaa ttgtcattgg tcgctcagtc
     4861 tattgaggcc accttatctg acaaggagct gattgctgag aaggtgcaga ccttattggc
     4921 aacaacacgc aatgcgtttt acattggtcg tggcaatgat tattatgttg ctatggaggc
     4981 tgcactaaaa ttaaaagaaa tttcatacat tcagtgtgaa gggtttgcag ctggtgagct
     5041 aaagcatggg actatttcac tgattgagga tggcacacct gttattggac ttatttcttc
     5101 aagtgagctg gttgctgcac atacacgtgg caatatccaa gaggtggctg cacgtggcgc
     5161 tcatgtgttg acagttgttg aggagggctt agagcgtgag ggagatgaca ttattattaa
     5221 taaggtgcac ccattcttag cgccgattgc tatggttatt ccgactcaat taattgctta
     5281 ctatgcttcc ttgcagcgtg gtttagatgt agataagcct cgtaatttag ccaaggctgt
     5341 tacagttgag taatagttgc ctgcttaaaa tgaggcagca gggtcctgaa gcctatttga
     5401 aacgagcttg acatgatgtt atgtcaggct cgttttttag tgcttgcctg gtcttatgat
     5461 aacgtattca tcttgtcaaa taagcatttc tgaagtaaaa tattaacgtt aagactaaga
     5521 agcttaggag agtaagatga cgttaccaaa ttgtttacaa tgcgattcag aatatgttta
     5581 tgaggacggg catttgctca tttgtccgat gtgttccttt gaatggacac gtggtgagga
     5641 ggagcctgag gaggaggggc ttgtcgtttt agatagtaat ggaactagat tagctgatgg
     5701 agacactgtt acgatcatta aggacctgaa ggtcaaggga gcgccgaagg atctcaagca
     5761 gggaactcgt gttaagcata ttcgtcttgt tgaaggtgat cacaatattg attgtaagat
     5821 tgatggcttt ggtgcaatga agctaaaatc agaattcgtc aagaagattt aataacaata
     5881 agcaaccaga tgactggttg tatttttata gaaaagtact tttcaatcca tcagaaaatt
     5941 tggtataatg gataaactat ttatatctag gagacaacat gacgtatatt atgcaggttt
     6001 tacccagctt gctggatggt gccttaatca ctttacaggt tttctttatt gtaattgtat
     6061 tatccattcc cttaggggct cttttagctt ttttgatgag ggttgacttt aagcccttgc
     6121 agtggctatt gacgctctat atttgggtca tgaggggaac acccttattg ttacagctca
     6181 tcttttttta ttatgttttg ccaagtgtgg gtgttacctt tgatcgtatg ccggcagcga
     6241 ttttggcttt taccttaaac tatgctgctt attttgccga gatttttcgt ggcgggatag
     6301 agactattcc aaatgggcaa tatgaggctg caaaggtgct gaagcttagt ccggtacaaa
     6361 ctgttcgcta tgttatcttg cctcaggtgt tcaagattgt tttaccaagt gttttcaatg
     6421 aggtgattaa cttagttaag gattcttcct tggtatatgt gttaggagta ggggatttgc
     6481 tattagcaag caagactgcg gcaaatagag atgcaacctt agcaccgatg tttattgcag
     6541 gtttgattta tttgctctta attggtttgg tcaccatttt atcgaagcag gttgaaaaaa
     6601 gatttaatta ttatcagtaa gggggtcata tgttagaact gaacaatatt tcaaagcgat
     6661 ttggtcacaa gcagatcttt gatggctttc atttgaccgt tgaagatggt gaggttttat
     6721 ctttggtagg gccatctggt ggtggcaaga ctactctgct ccgaatgctg gctggcttag
     6781 agcctattga ttcgggaaat attagctata atggcgagtc tgttcctatt gatcatttag
     6841 aaaaaagaag cctgcttggt tttgtttttc aggatttcca attgtttcca catttgacgg
     6901 tgctggataa tctcatcttg tctcctacca ttaccatggc tatgccaagg cctgatgcaa
     6961 agcaaaaggc tatggagctg ctggagcgcc taggtctcaa agagcatgca gctgcttatc
     7021 cttatgcgct atctggtggg caaaagcaaa gagttgcctt ggctagagcg atgatgattg
     7081 acccacagat tgtaggctat gatgagccga caagtgcctt agactctgaa ttacgtcagg
     7141 aggttgagaa attgattttg caaaatcgtg agatgggcat tacccagatt gttgtcaccc
     7201 atgatttgca gtttgctcag accatttctg atcgtatcat caagatcaat cctaaataga
     7261 agaagaggta gtgctatgac gttaaaaaag acccttctag tagccctatt tgctgctaca
     7321 gctacgcttt tagtagcttg tggcgctagt aataaacaga ctagctcaga tgcttgggat
     7381 tcctacaagc agaaaaagac gattacgctt ggctttgata atacttttgt gccaatgggc
     7441 tataaggacg agtcaggaaa aaataccggc tttgatattg agctagcaaa ggctgttttt
     7501 gaccaatatg gtatcaatgt taagtatcaa gccattaact gggatctcaa agaaactgag
     7561 ttgaacaatg gtaaaattga cctgatttgg aatggctatt ctgtgacaaa agagcgccaa
     7621 gctaaggtgg cctttacaga gccttatatg aaaaatgagc aagtcttagt gacgcaaaaa
     7681 tcatcgcaaa taagctcatt tgctgatatg aaaaataaga ccttaggtgc ccagtctggc
     7741 tcatctggct atgatgcctt tacgagtcat cctaaggtgc taaaggatct tgtcaaggga
     7801 aatgacgcta cccaatatga aacctttaca caagccttta tcgatttaaa aaacaagcgt
     7861 attgatggcc ttttgattga tagggtttat gccaattatt accttcagca agaaggtgag
     7921 ctagaccgct ataacattat cgcgagtgag tttgaaggtg aggattttgc agttggtgtc
     7981 cgaaaagcgg ataaaaccct acaaaaaaag attacacaag ccttaaaatc gctttatcag
     8041 gacggtacct tccaaaaaat ctctaaaaaa tggtttggtg aagatgtcgc aacagttcag
     8101 ttgaaatcat aagacgcaag caagacctaa tcagctcaga ggggttgaga ctagatacat
     8161 ttaaaagact taccttctaa aggcaagtct ttttatacgg cttattatta gctgatacgc
     8221 ttgatatgat agtgtttttt aattgctatg gagtttgtta ttggtgtgat ttgatgatat
     8281 atcaggtgcc aagcttcgtg tcgtctccag atactggtat gctgattgcc ctgtagctga
     8341 taggtgacta gcttggtgtt gtggctgatg gattgcatac aaaaggcttc aagctgattg
     8401 gaagaagaac gctgctgctc taaaaattgc ttggcattgt aagcttgtcc atcgcgatca
     8461 ataaaggtaa aggtcttggc aatgagctct tgataatctg ggatttgact tagcatgatt
     8521 ttctcgtttt tgtagagctt tttgtaaaca tattcacagt tgtcatcttt aggaagcttt
     8581 gcaggctcaa catgaatatc aatatcataa acagcaaatt gctcactcaa gagctgttcg
     8641 acctgctcgg ttatggcgtg actttcataa acagaaaggt cagggtgcat ctcaaggaca
     8701 atatctaaat agacattgct tccgtaagtg cggccgcgct gtgatttgac agcaatgatt
     8761 ttgggaattt tcaatatggc cttttcatat gctttgagct gcgtgctgtc aaagccatct
     8821 gataagctaa aggcgcttgc cataaaaata tcaaaggctg tttttagaat gaaaaaggta
     8881 atgataaggg cagccagcct atcaataata ggtagcttta aggaagcggc gataatagca
     8941 atagaggttc caatagaggt cacagcatca gaaagattat ctttagaggc tgcaaccaag
     9001 gcactggatc ttaccttttt tgataacgct ttattaaaag catatactcc aagcatcaca
     9061 agggctgaag cgatcccaac aatagcacct aatggatcga tagcagactg cttaccacta
     9121 atcatctgtt gaatagtttg caggagaacc tgaaagccaa caatgaacat gataaaggag
     9181 gttattaagc ttgaaaggtc ttcgattttc cagtggccaa agcggtgatt ggcgtctgct
     9241 ggctggctgg ccagatgaag tccgatgagc agagtgacat taccaacgat atcagacagg
     9301 ttgttgaagc catcggcaat caaggagctg gcatttaaaa gatagccagc aagaagcttt
     9361 gtgatgctaa gggccaaata ggtaacaatg ctaacaatgg gccctctttt tgctaaccga
     9421 aggttttcta ctggattgtt tggcataaaa actcctttgt aactgatgct ttcattatat
     9481 cataaaagct aagacaagct aaaagcctag agctatccta aatagggtat tccaggcttt
     9541 tcgatagctt atttggtgct ttggcgctta aaatatgccc ttgtctcaaa aatgacaaca
     9601 ggagataagg ctagtagggc gataagattt ggcagagcca tcaggccatt gacaatatct
     9661 gccagtatcc aaatcaactc cagcttaaga aagccaccaa gtcctaccat gataacaaag
     9721 atcaggcgaa aatagctgag gtgtgtcgtg ccaaataaaa agataaagca gcgctcacca
     9781 taatagctcc agccgagaat agtcgtaaaa gcaaaaagaa caagcgacag ggtcaaggca
     9841 taggtgccca tatgcccaaa gatagaagca aaggcagact gtgttaaggg tgctccctct
     9901 agtgcgctag tccactgacc agttaccaaa atggccagac cagtcagagt gcagatgatg
     9961 atcgtgtcaa taaaggttcc ggtcatagaa atcaggccct gttctactgg ctccttggtt
    10021 ttagcggcag cagcagcgat cggagcagag cctagtcctg attcgttaga aaaaacccca
    10081 cgtgcaatac ccttttgaat ggcgtcctta accaagcttc cggcaaagcc ccctatagct
    10141 gctgtagggg taatagcgga cttaaagata aggacaagca taggaagaag cttagtatag
    10201 tgaacagcaa taaccgttaa gcttgctcca atataaaaga tagccatgaa aggaacgact
    10261 gtttcagcca ccttggcaat agcttgaatg cctccaaaaa taatcatggc cacaacagca
    10321 gctagcaaga cactgattaa tggcgaagag atcccaaggc tatggtgtag ggatgaggta
    10381 atcgcattga cctgagcaaa tgtcccgatt ccaaacaaag ccactaaaat accagagaca
    10441 gcaaataagt tggctagagg cctccatttt tgccccatac catttaaaat gtagtacata
    10501 ggtccgcctg aaatctgacc attagcgtcc ttagtacggt atttaatggc taaaacgccc
    10561 tcggaatatt tggttgccat accaaagaag gcagcaaccc acatccaaaa aagtgcccca
    10621 ggtccaccag actttatagc ggttgcgaca ccaacaatat taccagtacc aactgtagca
    10681 gctagggctg ttgctagagc agcaaatgat gaaatatctc cttgcccctc attcttagca
    10741 aaaatgagcc taaaggcctt aggcaacttg atgacttgga gaaggctaag tctgctggtg
    10801 aggtaaatgc cagtaccaag cagcagtagc aacaagggtg ctccccaaac caaatcgtct
    10861 atccattttg cagcagctat catgcttaat tcctcaactc tcttaaccaa tgctgccaaa
    10921 agaaaaagcc acccctgcgg atagcctctg aagcatatga caaaacagca agcacaaaaa
    10981 atgctaagga agcatgatca tacggcttga tattttatct tctgtccttt tgcctgagag
    11041 attgagcagt cttgccttgc cccttcggcg cctaataggt ctctccagaa gcccgtccgt
    11101 caagcagtcc cgtccaacac ctgaacacct gagagtataa ctccttcggc gaaatccatt
    11161 cttctcctgc atgacatcat tcggtttatt aaattatgtc tatgataccc aaaaagccta
    11221 gtgatgtcaa caagcaattt aactgatggc taactccttg tttttatggt aacatcattg
    11281 tcctcttttt tctttttgac tgaaacatga tataatcgta aggttaataa aagtcactta
    11341 ttagacgata tgaggagaaa gcatgaatcc tttattagat ggaatgaatg ataaacaagc
    11401 agaggcagtt caaacgactg agggcccctt gttaattatg gctggtgccg gttctgggaa
    11461 aacgagggta ttaacccacc gcattgccta cttgattgat gaaaagtatg ttaatccctg
    11521 gaatattttg gcgattacct ttactaataa ggctgcgcgt gagatgcgag aaagggcatt
    11581 ggccttaagc ccagccacca aggatacctt gattgcgacc tttcactcaa tgtgtgttcg
    11641 tattttacgc cgtgaggcag atcatattgg ctacaatcgg aatttcacga ttgttgatcc
    11701 aggagaacag cggaccttaa tgaagagaat agtaaaagct ctaaatctgg atcctaagaa
    11761 atggagcgag cggtcgattt tagccaccat ttcaaatgct aaaaatgatc tcttagatga
    11821 aagagcctat gagctaggag cctctgattt gtatagccag acagttgccc gctgctacaa
    11881 ggcctatcag gaggagctca gacgaagtga ggctatggat tttgatgatt tgattatgat
    11941 gaccttacgc ctatttgatc aaaatcctga cgttctagcc tattatcagc agcgttatca
    12001 atatatacat gtcgatgaat accaagacac aaaccacgct caatatcagc tagtgactct
    12061 tttagcctca cgctttaaaa atatttgtgt tgtcggtgat gcagaccagt ccatttatgg
    12121 ctggcgtggt gctgatatgc aaaatatttt agattttgaa aaggattacc ctgatgcaag
    12181 ggtggttttg ctggaagaaa attatcgctc caccaagaaa atccttcagg cagctaacga
    12241 ggtgattcag cataatcgtc atcgtcgtcc gaaaaaattg tggactcaaa acgcagacgg
    12301 tgagcagatt gtttattata gggcaaatga tgagcgtgac gaggctgttt ttgttgcctc
    12361 aaccatcagc aatatgtgtc tagagctagg aaagagcttt aaagactttg ctgttttata
    12421 tcgtaccaat gctcagtccc gtacgattga agaagccttg ttaaaatcaa atattcccta
    12481 cacgatggtc ggaggaacca aattctacag cagaaaggaa attcgtgatg tgattgccta
    12541 tttgactgtg gttgctaatc cgtcagataa tctctccttt gaacgaattg tgaatgagcc
    12601 taaacgaggg gtagggccag gaaccctaga taagctccgc caatttgctt atgggcaagg
    12661 acagtcattg ttagaggccg cttcaagcct tgagcaatca ccgctaaaag gaaaggctgc
    12721 ccaagccatg ctggccttag cgagtctctt aagtgatttg agagctgatt tagaccagct
    12781 gagcattaca gccctggccg aggccttgct ggagaaaacc ggctatctgg atatgctgcg
    12841 cgtccaaaat accttagaaa gtcaagctag gattgaaaat attgaagaat tcctgtctgt
    12901 taccaaaagc tttgatgacc tatcagcaca gcagcaggag catgaagcag gtattgatcg
    12961 cttaggaaga tttctcaatg accttgcttt gattgctgat agtgatgatg gcaatgcaga
    13021 aaccgctgag gtaactttga tgactctgca tgcagctaag gggctagaat ttcctgttgt
    13081 ttttctcata ggtatggagg agggagtctt tcctttagcc cgagcagccg aggatcaaga
    13141 tgagctagaa gaagaaaggc gactagccta tgttggcatt accagagccg aggaatgctt
    13201 gtttttaacg aatgccaata cacgtaccct atttggtaaa agcagctata atcgcccaac
    13261 aaggttttta aaagagatgt cagagaacct tttaagcttc caaggcttgg caagacctgc
    13321 tcatgcttcc tttggtgtga cattttcgca gcagggtcaa cgacaatttg gcacaggaat
    13381 gagtctatca gaggctatcc agtccagaaa atcaatggca cagcctgcca gagcagcctc
    13441 aacatctaca ccgctgccct ttggaccgaa tgcagctact tcaaagcaag ccgttgattg
    13501 gcagattggt gatattgccc atcataaaaa atggggtgct ggaacggttt tagaggtcaa
    13561 gggatctggt aagaccatgg aattaaccat tagttttcct gatgtcggat taaaaaaact
    13621 ccttgccagc gttgctccta ttgaaaaaaa ataaaaggta cagcttatgg gcaatttgca
    13681 tagtcacttg gataagggct ttgcaattgc ggtttagttc tgcgatttaa gaaaagaagt
    13741 aagcaaggat tttatcagtt aaccacatac caagcttttg atggccttga tgccggagag
    13801 agcttggtat ttttttattt ttaaaaaaat cacaaaaaat gatttattct gagcataatc
    13861 cttgcaaatt aaaatgagaa gcgtataatg gcaatataaa ttaaataaca agtggtcact
    13921 tttgttaata
//
LOCUS       DARYXZ010000054        13214 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYXZ010000054 DARYXZ010000000
VERSION     DARYXZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13214
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(241..489)
                     /locus_tag="TV186_001656"
     CDS             complement(241..489)
                     /locus_tag="TV186_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL1533029.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(543..1463)
                     /locus_tag="TV186_001657"
     CDS             complement(543..1463)
                     /locus_tag="TV186_001657"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL1533030.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            1697..2326
                     /locus_tag="TV186_001658"
     CDS             1697..2326
                     /locus_tag="TV186_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1533031.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            2425..3702
                     /locus_tag="TV186_001659"
     CDS             2425..3702
                     /locus_tag="TV186_001659"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL1533032.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            3716..4378
                     /gene="deoC"
                     /locus_tag="TV186_001660"
     CDS             3716..4378
                     /gene="deoC"
                     /locus_tag="TV186_001660"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL1533033.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            4365..4754
                     /locus_tag="TV186_001661"
     CDS             4365..4754
                     /locus_tag="TV186_001661"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL1533034.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            4845..5897
                     /locus_tag="TV186_001662"
     CDS             4845..5897
                     /locus_tag="TV186_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL1533035.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6024..7556
                     /locus_tag="TV186_001663"
     CDS             6024..7556
                     /locus_tag="TV186_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533036.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            7549..8613
                     /locus_tag="TV186_001664"
     CDS             7549..8613
                     /locus_tag="TV186_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533037.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            8615..9571
                     /locus_tag="TV186_001665"
     CDS             8615..9571
                     /locus_tag="TV186_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533038.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(9609..10865)
                     /locus_tag="TV186_001666"
                     /pseudo
     CDS             complement(9609..10865)
                     /locus_tag="TV186_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11385..13100)
                     /locus_tag="TV186_001667"
     CDS             complement(11385..13100)
                     /locus_tag="TV186_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1533039.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         3782 a         2330 c         3062 g         4040 t
ORIGIN      
        1 gcgatcaaga cgcagaacag gggctatagc agcctgatgt gagacaggaa ggacttactg
       61 tcctaccagc tacagtcact acactgctag agcttgcggt gtgagcagca gtaagaggca
      121 aaggcgttac cccagaggga ttgatggatc accatcacta gtttggagcc attagctgtg
      181 ccaaaggttt tctaaagcca aaaagaaaaa actccgattg gagttttcat tggttatgta
      241 ttagctaagc tttgcagcaa gacgtgcttt atcgcggctt gctttatttt tatgaatcaa
      301 accttttgat tgggctttat caatgcttga agaagcagcg cggaaaagct cttcagatgg
      361 gttagcttca aatgccttga tagcagtacg catagctgat ttttgtgctg aatttttttc
      421 gtttgcttta acgttaagct cagcgcgttt aatagctgat ttaatatttg ccaatgtttt
      481 cacctccaaa ttaatctaac tacaccatta tatagaaaat ataggtgttt ggcaagcact
      541 tatcactttt tgagataaat ttcatcaatt ttatggtctg cagctttatg aagaatgagc
      601 tcagctcgat tgcgtgtagg ctcaataaac ttttccagat tttctaggtt aattgttttc
      661 cagacttttt ttgcaaaggc aatggcttca ttttgtggca atgaggtata tctagtgtaa
      721 tagttagccg gatcatgctt agccagctct aaaaggctta agaaccgttc caaataccat
      781 tgctcaatat gatggctatc tgcgtcaata taaattgaaa aatcaaaata atcactcata
      841 tacaatcgat tattctgttg attttgaaaa acattaatcc cttcgatgat gaggaagtca
      901 ggattggtaa aggtttgctg ctgatcagga acgatatcat aaatctcatg cgagtaaaca
      961 ggggctgatg cggtttgtcc tcccttgaca gtatccagaa agtttaacaa tagctccata
     1021 ttataggatt ctgggaagcc ctttcgattc agcatattgt ttttgatcag tgtgctatta
     1081 gggtacaaaa aaccatctgt tgtgaccaac tcaacagtgc tggtcttgtg tgtgcgcgcc
     1141 aaaagaagct gcaataacct gctagttgtg gacttaccga cggcaactga gccagaaatc
     1201 ccaataataa agggtctttg ctgaatatct ttttttagaa agaggctttt agaaaaagac
     1261 aggttttctt gagcgatttt atagacttga atgagatgaa tcaagggaag gtaaacctca
     1321 acaacgtcgt tgatatcaat attatcattc aaactggtga tgctagtaag ctcctcttga
     1381 gtcaataagg gcttgctttt ttgatgtaat tgcttccagg attttctgga aattttttca
     1441 aaagtaataa attcgtttga catagttact cctactaatt ggcagtgctt acattataac
     1501 atgtcaataa aaaaattgaa aaatgtttcg tctgaaattc ttaaaaaaac actgaaaaac
     1561 cctataaaaa tcgaacaatt ttagcctaac aattggctaa tataaagtta atcggtcaat
     1621 gttcggaata tatggttcga taaacgaaaa accaagaaaa acaaacgtct tgtaaaccat
     1681 ttcaaagtgt gatagaatga aaaagcatcg aaaaaagata ggaaaacaca tgacaaaaat
     1741 gtattatgat gaaaatccag atagtgctca tgatatccat caattgacgg tcaatttgtt
     1801 aggacagtcc tttacttttt tgacagattc tggtgttttc tcaaaaagaa tggttgattt
     1861 tggaagtcag gtcctgctca acacattaga ttttcaagaa ggtgatcgtc tgcttgactt
     1921 gggctgcggc tatgggccgc taggacttag cttggcaaag gctcaaggtg ttgaggcgac
     1981 tctagtagat attaatcatc gcgctgttgg cttagctaag cagaatgctg agagtaatca
     2041 ggttgaggcg accatttttc aatcaaacct ctatgacggt gtgacaggga catttgagca
     2101 catcattagt aacccaccta ttagggcagg gaaaaaagtg gttcatgaga ttattgaaaa
     2161 gagtattgat tttttaacta aaggcggtga tttgacagtc gttatccaaa agaagcaggg
     2221 agcaccaagt gctaaagaca aaatggaggc cgtttttggg aatgtgacta ttctcaaaag
     2281 agaaaagggt tactacattt taagaagtat taaggaaagg aattgagctc aagtgtaaaa
     2341 agtggtatta aaaagcatag cggtatttta gtaagagttg ccttctaata tcactatttt
     2401 ctcagagctt ttggtatctt gttgatgaga gcagttgatt taatccaaaa aaagcgtgat
     2461 ggtaaagagc tatctaccga agagatccag tggctgatta atggttatgc caatggtact
     2521 gtgccagatt atcaaatgtc ggcttttgca atggcgatct atttcaaggg aatgtctaca
     2581 cgagaaactc gcgatttgac catgagtatg gttgagacag gtgagcagat tgatttgtca
     2641 gctatagctg gtatcaagac ggacaagcac tcaacaggtg gtgttggtga taaggtgaca
     2701 ctcatcttag ctcctctagt tgctagcttt ggcgttcctg tagcgaaaat gagtggacgc
     2761 ggcttaggcc acaccggtgg aacgcttgat aagctagaat ctatcaaggg ctttcagatt
     2821 ggtcggaccc aagaggaatt tatcaagcag gtacaagaga tcggactttc agttattgga
     2881 caatcagata agcttgtgaa ggcagataag ctgctttatg ctcttcgtga tgtgacggca
     2941 accgttgata ttgttccttt gattgcaagc tctgttatga gtaagaaaat tgctgctggc
     3001 gctgatagta ttttgctaga tgttaccgtt ggtgacggtg cctttatgaa gactattgaa
     3061 gatgctgaga agctgtctag actgatggtt gaccttggta aggaggttgg gcgtcagaca
     3121 gtggctgtca ttacagatat gagtcagcct cttggtcgtg ctatcggtaa tcgcttagag
     3181 gtgctagagg caattgatat catgaaaggc aagggacgca aggatattac tcactttatt
     3241 tgtgagctag ctcagattat gctggagctt gctggtgctc aacactctct tgaggatatt
     3301 caccatcatt tggttggcgg agcagcctta aaaaaattag aagagatggt tgtttatcaa
     3361 ggaggtgatc ttgaggacct ttatcgtcca tcacaggcgg ctgttcaaac agaggttttt
     3421 gcgtcagaag atggttacat cacagcattg cctgctcttg agtttggatt gtttgcaatg
     3481 aggctgggtg ctggtagagc agtcaaaaca gatagtctgg attatgaaac agggattgtc
     3541 tttgacaaga aggttggtga cgctgtcgct aagggagagc gcattgcagt tgtcttttca
     3601 caggaagccc tagacgaaaa aatgcttaca gaatttgaaa aaaatgttaa aataggggcg
     3661 gaacacctag aggctaacga aattatcaaa atcatttcct aaggaggagt ataacatgaa
     3721 tattaacaag tatattgacc acacactact aaaagctgac agcgttcaat cgcagcttga
     3781 ccaattaatt gaggaggcta aagcctatga ctttgctagc gtttgcgtca acccttgctg
     3841 ggtagcctat gctgcaaagg ctttaaaggg aacagatgtt aaggtttgta cagttgttgg
     3901 ttttccttta ggtgcaacta cctcagcaac aaaggccttt gaaacaaagg acgctattga
     3961 aaatggtgct gatgagattg atatggttat caatattggt ctgttaaagc agggtgacta
     4021 ccaagctgtt gaagatgata tgcgtgcagt ggtagaggct agcggagaca aattagtcaa
     4081 ggtgattatc gaggcttgcc tcttgactga tgatgaaaag gttaaggctt gtcagttggc
     4141 ggtaaatgca ggtgttgact ttgtgaagac ctctactggt ttttcaactg gcggtgcaac
     4201 cgtttctgat gtcaagctaa tgcgtcaaac agttggtcca gacattggcg taaaggcagc
     4261 tggtggtgct cgttctctag aggacgcttt agcttttgtc gaagcaggag ctacacgtat
     4321 tggaacttct gcaggggtaa ctattatgaa aggtgaagtt gccaatggag gctactgatt
     4381 tagtttcgtt agccattgaa gctagtaaaa gggcttatgt gccttactca catttcccga
     4441 tcggagctgc tttaaagaca aaggacggaa caatctatac tggcaataat atcgagaatg
     4501 ccagctttgg cttgaccaat tgtggggagc gaacagctat ttttaaggct gtttctgagg
     4561 gacatcagca gcttttagaa attgccattt atggagagac tgatgagcca atctctcctt
     4621 gtggagcctg tcgtcaggtc atggcagaat tttttgaagc cactgctcca gtaacgctaa
     4681 ttgctaagga cggtcgtacc atgcgcacaa ctgttggcga gttacttcct tattcgttta
     4741 cagatttatc gtaatctggc ttaattttgt tatctagcca ttaggcttta tatttacttt
     4801 cggcaattgg tttgctagaa atatttttag gagggttcat attcatgaac aagaaattta
     4861 ttggtgttgg tttagcttct gtagctttat taggtttagt tggttgtggt aatcgtaacg
     4921 cttcaaaggg atctggtgat gctaaaacag atttgaaggt agcagtggtt actgacactg
     4981 gtggtgttga tgataagtca tttaaccaat cagcttggga aggcttgcag gcttggggta
     5041 aggacaatgg actaacaaag ggttcaggct ttgattactt ccaatctaca aacgagtctg
     5101 aatatgcaac taacattgat acagcagttt ctagtggtta tgaggttgtt tatggtatcg
     5161 gatttgcctt gaaggatgca atcagtaagg ctgctgatga caacaacaaa gtacaatttg
     5221 ttatcattga tgatgttatc gaaggcaaag acaatgttgc tagcgtaaca tttgctgata
     5281 acgaagctgc ttaccttgca ggtattgcgg cagctatgac tacaaaaaca aaaacagttg
     5341 gttttgtagg tggtatggaa ggaacagttg ttacacgctt tgaaaaaggc tttgaggcag
     5401 gcgttaagtc tgttgatgac tcaatcaaga tcaaggtgga ctacgctgga tcatttggag
     5461 atgccgctaa gggtaagaca attgcagcag cgcaatacgc agcaggtgct gatgttatct
     5521 atcaggtagc tggtggaaca ggtgcgggtg tcttcaacga agcaagaaca attaacgaaa
     5581 aacgtgacga agctgataag gtttgggtaa ttggtgttga ccgcgaccaa aacgaagaag
     5641 gtaaatatac atctaaggat ggcaaatcat ctaactttgt acttgcatct actataaaag
     5701 gtgttggtaa ggctgttcaa ttgatcaata agcaggcagc agataagaaa ttccctgcag
     5761 gtaaaacaac tgtttatggt ctgaaggacg gtggtgttga gattgccaca acaaatcttt
     5821 ctaaagacgt tatcaaagcc atcgaagaag cgaaagaaaa aattaaatct ggtgacgtaa
     5881 aagttcctga aaagtagtta ctggaaaaga gcgaccttcg tcggtcgccc tttttagagt
     5941 ggaacacctt ttgcttcagt aaaggttgtg acaaatggct ggctttactg aaacaaaaga
     6001 ttaaattgaa aggaaataat cctatggcac agcatgtcat tgaaatgaaa gagattacaa
     6061 aaaaatttgg tgattttgtt gcgaatgacc atattaattt gaatgtcaga aaaggcgaaa
     6121 ttcatgcatt gttaggagag aatggtgcag gtaaatcaac gttaatgaat atgttagctg
     6181 ggcttttaga gccaactagt ggaaacattg tcattaacgg tcagcctgtt gttattgact
     6241 ctccttccaa atctgctaga ttgggtattg gaatggtaca ccagcacttt atgctagtag
     6301 aagcttttac agttgctgag aatatcattt taggaaatga agttgtcaaa aacggttgtc
     6361 ttgatttaaa aaaggccagc aaggacatta aagagctttc tgagaaatat ggtttagctg
     6421 ttgatcctac tgccaagatt gctgatattt ctgtaggggc acagcagcgt gttgaaatct
     6481 taaagacctt atatcgtggt gcagatattc ttatttttga tgagccaaca gctgttttaa
     6541 cgcctgctga aatacaagag ctcatggaaa tcatgcgtaa ccttgttaag gaaggcaaat
     6601 ccattatttt gattactcat aagctggacg aaattagagc agttgctgat agagtcactg
     6661 ttattcgacg tgggaaaagt attcaaacag tagatgtagc aggtgcaacc tctcaggact
     6721 tggctgaaat gatggttggg cgttcagttt cctttacaac agctaaaaag gcagcagagc
     6781 caaaaggggt ggtgctgtcg atcaagaatt tagaggtcga tgaaaatcgt ggaatcccag
     6841 cagtaaaggg gctttctctt gacgttagag ctggtgaaat tgtggggatt gcagggattg
     6901 atggtaatgg tcagtcaggg ctgattcagg ccattacagg cttgagaaag actagatctg
     6961 gtagcattac aatcaaaggt caggaggttg ttcatttaag ctcccgtaaa atcacagagc
     7021 tatcagtggg gcatgtgcct gaggaccgtc atagagatgg cttagtgctg gacctttcct
     7081 tggctgaaaa tactgccctt cagacctatt ataaagagcc actaagtaag aacggtattt
     7141 taaattacaa tacaatcaat gattatgctc gtagactgat gaaggaattt gacgttcgtg
     7201 gtgccaatga attggttcca gctcgtggat tttctggcgg taaccaacaa aaggctatca
     7261 ttgcacgtga ggttgaccgt aaccctgatt tattgattgt cagtcagcca actcgcggct
     7321 tggacgttgg tgctattgag tacattcata agcgtttgat tgaagagcgt gacaaaggca
     7381 aggccatcct cgttgttagc tttgagcttg acgaaatctt gaatttatct gaccgtattg
     7441 cagttattca tgacggtaaa attcaaggca ttgtgttgcc tcaagatacc aataagcaag
     7501 aattgggaat tttgatggct ggtggttcca ttgataagga ggagagtcat gtctaaaaat
     7561 gcacaaaaga ttgctgtgcc aatgatttct atcttgttag gattcttact tggcgctatt
     7621 gtcatgttta tctttggcta tgatccaatt tggggctatg agggcctatt tcaggtagcc
     7681 tttggtagta tcaaaaatat tggtgaaatc ttcagagcga tgggaccact aatcctgatt
     7741 gcacttggtt ttaccgttgc tagccgtgcc ggcttcttta atgtcgggct gtcaggtcaa
     7801 gctttggctg gttggattgc tgcgggctgg tttgctcttg tcaatcctaa tatgcctcgt
     7861 ccgcttttaa ttctgatgac tgtcttgatt ggtatggttg ccggcggaat tgctggcgct
     7921 attccaggta ttttgcgagc ttatcttggt acgagtgaag ttattgttac cattatgatg
     7981 aattatatta ttctgtatgt cggtaacgct atcattcaaa gaggctaccc tgaaagtgtt
     8041 aagcaaagta ttgattcaac catacaggtc agtgataatg ccagctatca aagtcaatgg
     8101 ctgtcagatt taaccaataa ttctcgtatt aatatcggta tcttttttgc gcttattgca
     8161 attgcagtta tttggttctt actaaacaaa acaaccctcg gatttgaaat tcgttcagta
     8221 ggtcttaatc cacatgcttc agaatatgca ggtatgtcct taaagcgtac gattatccta
     8281 tcaatgatca tttcaggtgc tttagcaggc ttgggaggag ttgttgaagg cttgggaacc
     8341 tttgagaatg tttttgtaca gggaagctct ctagcaattg gttttgacgg tatggctgtt
     8401 agcttgcttg ctgccaattc accgattggt atcttcttct catcattcct atttggggtg
     8461 ttgagcatag gtgctcctgg tatgaatatc gcaggaattc caccagaatt ggtaaaagta
     8521 gtgactgcct caattatctt ctttgtaggt gctcactacc ttatcgaacg ctatattatc
     8581 aggcctaaaa aactagtaaa gggaggtaaa taagatgagt ttagttacta tttttgcttt
     8641 attggtttca tcaatgctta tctatgctac acctcttatt tttacaagta ttggtggtac
     8701 cttctcagaa cgagctggtg ttgtcaatgt cggccttgaa ggcattatgg tcatgggggg
     8761 gggttcaggc attgtcttta atcttgaatt tgctcatatc tttggtaaag ctactccctg
     8821 gcttgcagtt ttggtgggag gagttgttgg attgatcttt tcattgatcc atgcgcttgc
     8881 aacgattaac tttagggcag atcacattgt cagtggtaca gtgctaaatc tgctggcacc
     8941 atcgcttgcc attttcttag ttaaggtgat gtacggtaag gggcaaactg ataatatcca
     9001 gcaatcattc ggtaagtttg attttccgat tctctcaaaa attccagttc ttggagatat
     9061 attctttaga aatactagct tagttgggta tttagctgtt gccttttctt tcctagcttg
     9121 gtttgtgctt tacaaaacaa gatttgggtt gcgtttgcgc tctgtaggtg aacaccctca
     9181 agcagctgat acacttggta ttaacgttta cctcatgaaa tattatgggg ttatgatctc
     9241 tggttttctt gggggtattg gtggagctgt ctatgcacaa tccatctctg ttaacttcgc
     9301 agtgacaacc attttaggac ctggatttat tgcccttgcc gctatgattt ttggtaagtg
     9361 gaatccggta ggtgctatgc tatctagctt gttctttgga ttatcacaaa gcttagcagt
     9421 tattggggca caattaccag tattggaaaa aatcccaacg gtttaccttc aaattgcgcc
     9481 atacctattg accatcatca ttttggctgc tttctttgga caagcagtgg ctccaaaggc
     9541 agacggtgtt aattacatca aatcaaaata aaaaaagctc aatgtcaact gtagtgggtg
     9601 actgatagct aagcacgaga gaagacgaat gtcgtcttct cttttgtgat attcaaagcg
     9661 aggtagatac gttttttaaa gttgtcaaag ttccgaaatc cgaaagcatt gcgcttgata
     9721 tctttgataa gtttgttagt ggcttctaac ttagcgttag aataaggcag ttgaatggca
     9781 ttggtgatgt aatcttggta gcgactaaag gtatttagag ctgttttaaa agtctgatta
     9841 agatgtggta gtgtgtcatg aattaaacca aagaaatgct tggcattctt ttcttgcagg
     9901 tgaaaaagga gcagctggta caggtcataa taagagttta actcaggcac tagtgagaag
     9961 atcttattga gacattctct aggagttaag gtttgtctga aggtgcggga atagaaaggc
    10021 ttaagagacc gttttctgct atccttttga ataagcttcc agtagtactt aagagctcta
    10081 tatttaagag acttcttgtc aaatggtttc atgatgtcac tacgtatttg cttgagagct
    10141 ctattgatgt gctggacaat gtgaaaacga tcgagaacga ttttagcctt aggaaataga
    10201 attttaatga gaggaatata acttccagac atatcgacag tgacgacttt caccttgttt
    10261 ctagcctctt tagagtactt aaagaaatga tttcggatgg ttgtttgacg tctattatca
    10321 agaatggtaa tgattttctt agtgttaaaa tcctgagcaa tgaaggctaa tttaccttac
    10381 tgataagaga actcatccca agagagaact tctggcaaat tggcgtaatc ctctcggaaa
    10441 tgatactgct taagcttgcg atagacggta gaagtggaga tagcgagctt agaagcgata
    10501 tgggtgagag cctttctgtt gagtaaaagc tgagcgattt tctgtctcac tatctcagaa
    10561 atttggcaat ttttcttaac cagggtagtt tcagatacag tgacttttcg acaggatttg
    10621 cattgaaacc ttcttttttt caaacgaatg agactaggaa agcctccaat ttcgataaag
    10681 ggaattttag agggcttctg gaagtcgtat ttgatttgtt ttcccgcaca cagtttacat
    10741 ttaggagggt tatagtctag tgtagcgatg acttcaatat gagtatcatg ctggatagct
    10801 ttagtcaagg tgatatgttt gtctttgatt ccaatgagtt gtgtggtatt attgaggtgt
    10861 tccataagat accttctaaa tgatagttta gtcgcttttc atgataagtc ttatgggact
    10921 tttttgatac tcaaaaagcc ctataatctc cacagtagcc ttacccacta cagaaattat
    10981 agagccatct tagaacactg gacttgttcg ctttttaatg aattaaattt agtagatcct
    11041 ttaaaggcat gctatcaagc tttttatcct tgacttttgt ttagcaagtg aagtgttcac
    11101 aaaagctagc taaaacactg agctgacaat gtagagaatg gctcgttttg acaaggttag
    11161 agtgcttttt gctgtatggt ttttaatcca cgcacctgaa aaagaaagga caggacctgt
    11221 gcgagcttac ttgtggttag taggtttcaa ttcatgctcc caaaaaggaa gcaacgcaac
    11281 tctgagaaag gtcttagacc actttcccag tttgcctcac agctaatggt gtaaaacaaa
    11341 tagaccaccc tgtaacaggt ggtcatggtt agatatcagc tcatttaaga gacaaaggcg
    11401 ttgatttcag attcaatatt ggcaattttt tcttcggcaa gcgcaagggt gtcaccaaca
    11461 gttgcgatat aaaatttaat ttttggctct gttcctgatg gtcttacagc aaaccatgaa
    11521 tcatcagcta gggtatattt taagacattg cttggaggag tggttagctg ggtttgacca
    11581 gctttatgag ttgccgtctg actgaggaaa tcctctgtta acacaatatc agtgtgatta
    11641 aactgcgcag gggcatgctt gcggaattta tccataatct gtttgatttc agctgcgcca
    11701 tcaacaccag acagtgtaac agaaatggtt ttttctgcaa agtagccgta ttctttgtaa
    11761 atgtcatcaa taccatcagc aagggttagt ccacgagagc ggtagtaggc agcaatctca
    11821 gccaccaata gcaccgcttg aatagcgtcc ttatcacgta caaatggttt aatgagataa
    11881 ccaaagctct cctcaaagcc aaacatatag gtgtaattgt gcttttcttc aaattcttga
    11941 attttttcag caatgaactt gaagcctgtt aagacattaa acatggttgc cccgtagctc
    12001 tctgcaattt tagtcactaa ttcagtagag acaatggatt tggcaagagc ggcattgtta
    12061 ggtagggttc cagcctgctg atgtgcttct aaaatatact tagcaattaa agcaccaatt
    12121 tggttgcctg ataggttgcg atagctgcca tctgcctgcc gaatttcaac cccaagacgg
    12181 tcagcatctg gatcagtagc aacaagaaca tcagcatcaa cctgacgtcc aagctcctca
    12241 gcaagagtaa atgcctcttg actttcagga ttaggagatt tgacggtaga aaaatctgga
    12301 tctggcttag cctgcacctc aaccacctga acggacttaa agcctgcttg tgccaaggca
    12361 cgacgtgcta gcatttcacc tgttccatga agaggtgtat agacaatttt catgtcacga
    12421 ccatagtcat tgatgaggtc ttggttgata ttgacctttt tgacctcttc taaataagca
    12481 aggtcaacag cttcaccaat aacctcgatg agcccattag ctttggcttt ctctaaatca
    12541 gcaagcctaa tggcaaaggg gttatcaatc gcacgaatgt aatctgttag agcgtcggcg
    12601 tcagctggag gcatttgacc gccgtcagac ccataaacct tatagccgtt gaatggtgca
    12661 gggttgtgac tggcagtaac catgataccg gcaaaagcac ccaaatgtcg cacagcaaag
    12721 gaaagctcag gtgttggccg aaggctttca aaaacgtatg atttaatgcc atgagctgct
    12781 agtacctgtg cagattcaaa ggcaaattct ggagaaaaat gacgagaatc ataggcgata
    12841 gcgacaccgg ccttcttagc agcttctccc tttgactcaa ctaatgctgc caagccctca
    12901 gttgcttggc gaacaacaaa aatattgata cgattcgttc cagcgccaat atagccacgc
    12961 ataccagctg ttccaaattc aagattggtg tagaaggcat cttcctttgt tttttcgtcc
    13021 atgctaagta attcatctct taaataggct ggtagatctg gaatatcaag ccatttttga
    13081 tagttttctg tgtaagtcat agtattctcc tttatatttt taaccgcttt cattatatca
    13141 tgttgaaaag gaaaaatcac ttattttctg taatagcttc caatcatttt ttcacataag
    13201 gatcaatttc cttg
//
LOCUS       DARYXZ010000055        12984 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYXZ010000055 DARYXZ010000000
VERSION     DARYXZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12984
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(22..1071)
                     /gene="citC"
                     /locus_tag="TV186_001668"
     CDS             complement(22..1071)
                     /gene="citC"
                     /locus_tag="TV186_001668"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL1533040.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1338..2401
                     /locus_tag="TV186_001669"
                     /pseudo
     CDS             1338..2401
                     /locus_tag="TV186_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TV186_001670"
     CDS             complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TV186_001670"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL1533041.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3364..4059)
                     /locus_tag="TV186_001671"
     CDS             complement(3364..4059)
                     /locus_tag="TV186_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1533042.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4212..5615)
                     /locus_tag="TV186_001672"
     CDS             complement(4212..5615)
                     /locus_tag="TV186_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL1533043.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            5997..6341
                     /locus_tag="TV186_001673"
     CDS             5997..6341
                     /locus_tag="TV186_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533044.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6359..6754
                     /locus_tag="TV186_001674"
     CDS             6359..6754
                     /locus_tag="TV186_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL1533045.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6804..7925
                     /locus_tag="TV186_001675"
     CDS             6804..7925
                     /locus_tag="TV186_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL1533046.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8107..8415
                     /gene="citD"
                     /locus_tag="TV186_001676"
     CDS             8107..8415
                     /gene="citD"
                     /locus_tag="TV186_001676"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL1533047.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8403..9290
                     /gene="citE"
                     /locus_tag="TV186_001677"
     CDS             8403..9290
                     /gene="citE"
                     /locus_tag="TV186_001677"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL1533048.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9292..10824
                     /gene="citF"
                     /locus_tag="TV186_001678"
     CDS             9292..10824
                     /gene="citF"
                     /locus_tag="TV186_001678"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL1533049.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10817..11377
                     /gene="citX"
                     /locus_tag="TV186_001679"
     CDS             10817..11377
                     /gene="citX"
                     /locus_tag="TV186_001679"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL1533050.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11408..12799
                     /locus_tag="TV186_001680"
     CDS             11408..12799
                     /locus_tag="TV186_001680"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL1533051.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3802 a         2590 c         2874 g         3718 t
ORIGIN      
        1 tagagagggg gtagttgttg gttaataatg cttaaggtct gttgctgctt tgatcttagt
       61 tatcgtgggc tgagcagcct cgctcctaaa aaagtcaagt gaggtcttag gaaggagtag
      121 ctctaagaga gcataatcat cgtccttgat ggcctgtctg gcaagagagg cgctgatgat
      181 tttgccttct gcaaaggttt ttctagggat aacctgcaca tcaatgctat agcaaggcag
      241 ctgcttgagc atgacagtgt tgtaatgctg tgtgaccatg ctagtaggct cttcgccaac
      301 ataacgactc ttgatttgga gtttttctgc aatgtgacgg aaaatgacaa tatccaattt
      361 agcttgacta tcaataactg ctagctcatc tttttgaaaa taagcaggaa aggttgcctg
      421 actaatcatg taaggtccac tatcgtggta tatgatattt gctaggtgtg cagttccttt
      481 gatgattaat tcctttcgga tatggtaggg gatcaggcta ctgtcttgac tgaccataaa
      541 gagatgaacg agctcgttgt cagcgcaggc cttttcaatc agatgcagat gaccaagggt
      601 aaatggatta gcatttaaaa cgattgctgc ggtcttttga ggactgatct ggggcttttc
      661 tagctgtgac aggtagtgct caaagcccct ttttttattt tctaaaaaac aaagagtatc
      721 atcaaccatt gcaatgacat gaaagccaag acttagcaat agaggggcag ctgctatttt
      781 agtgtagata aacagatgat gatgcccacg tgagtaggcc tcctcaatca gatgtgagac
      841 aatgtgatta agtaagcctt ctccttggta ggcttgatca acagctaagc agcgcaggct
      901 attgccgtac aaagagccag tagcaatagg ctcgccttgc tcgtcaataa tagcacaggt
      961 ataatctaaa tgagggtctc ttctaatgtg ctgtctttgt aacaaacgat caatttttgc
     1021 tttttgctgc ttgtcaaagg gaaaaatatg ctgtatcaag tgctgcgtca tatgctcacc
     1081 tcttattacg aaattatcct cttgccttta ttatagcacg ctatagggct tattcttaag
     1141 catcttagct ggtttatgaa aagaatgcac aaaaaagaca tcaatgacct attgtctctg
     1201 atgtcattat gatatgatta ggacttttag ataaatgatt aaggtatgga ggatttaagc
     1261 ctgcaaaagg tggcaataat aattctgact tatgctataa tagagctatt gatattaagg
     1321 gggataaagg ggctggtatg ctttcgattc taatgacttt atttgttggg acgctgggag
     1381 ggcttgttgc taagcggctg agtattcctg ccccttttat gattggcagt atggtagctg
     1441 ttgccctagc ttctatcctg acaaagcagg tagaggctat taaccccatg aagatttttg
     1501 ctcagattat tagtggtgcc tatattggcc aaagcgtcag caaatctgac ctgcttaatc
     1561 tgcccaagct agccaagtct attattagtc tcatgtcctt gttcacgctg aatatgtttc
     1621 ttcttggtgg ggtatttgtt tactgctttg atcttgatcc tgtaacagcc ttgttgagct
     1681 gtttacctgg tggcattatg gacgtttctc ttatggcagt tgatatggga gcaaaggctg
     1741 atatagttgc gacattacag tcggctcgac tggtcggtat gctcttgttt cttcctgttt
     1801 gggtgacgtt ttgggtcaat cgctttgacc caaaagcaaa agctactaaa aaaaaaagat
     1861 agtcaaaagc gctagctccc aagatacaag accttctagg aaagagcagc tatggaataa
     1921 tgtccaggtt ttaagcattg ctaccattgg aggtttgatc ggtttagggc taaagatacc
     1981 tgtaggcgct ctgattgttt ctttgctttt ttcaacagca ctgaaggtgc ttcggcaaac
     2041 aagtcaaatg ccaagtacac ttcgttatat agcgcaggtt tttgctggct ctattattgg
     2101 aacaagcttt actcaggata gtttgcttca aatgggacgt ctgattgttc ctattctttt
     2161 acttttgagt agctatctga tcatcaatct cttttttggc tatatcatgt ataaaaaagg
     2221 tatcttggat ttgcaatcgg cactctttgc ctcatcgcct gctggtgcga cagacatttc
     2281 actattggct ggtgagcttg gcggagatat gcctaaaatc gctggtattc aaatcagtcg
     2341 aaccctctat actgttgtca tcatgccctt gttggttaaa tggctcatta gtatatggta
     2401 aacagaaaag cccctcagag cataaaccag agatacctag tcattaccaa ataacatatc
     2461 aaggatcttg ttcaggcttg gagctgctat aattgatttt ctaaaaaagc aaagtagagg
     2521 cttagcacta gcagatcagc agtccctcca ggactgagat gcttttggat cagcttgtcg
     2581 ttgtaggctg acaaggcagc ctttaagtca gcagtgctca aagagctgtt gtgcaatagc
     2641 agcatgtcct gtttgacttg ccgccaagct ttgatgcctc ctcggtgaat caggttgcca
     2701 tcttccacaa tagacatgag gtaaaccagc agttgcagtt gagcggtctc ctgatcagtg
     2761 ctgcgaaggc tcttgcgcaa aaaaggcagc gccttgtgag caattgtagg atagccctcg
     2821 ctggcttctc ctctagggcc ctttataccg taatctagaa agagcttctc accataggtg
     2881 agctcttttt ttaggtctaa gctaccaaaa tcagtctcaa ggagatgagc tgttagaggc
     2941 ttgacaagct gacaaatagc cagactatcc tcctcagtaa aggctgttac atggtccaag
     3001 agctgtggtt gatcggcaag atacattccc gttgccccaa gcagaagtgc taaggaaaaa
     3061 ttgactccct tatgggtatt gactccctta gttgcgctga acatggcttg ctcagcctca
     3121 atgcctgagg cacgcaagcg ctcaaagatc agaccaggat cttccttagc atggtaaaaa
     3181 ccaatgtcta aataaatctt aaaaaagggg gctaaggcca gagcgctatc aacaaaggtt
     3241 aagaagctca tgtcatcatg agccccgtta tcaagctgat ccacaagccc aggcttagga
     3301 gataaggaca cttcgtaaag taaagccttt agagcaagcc tgctaatatc atcaaatacc
     3361 ttcttagtca tcctgacgcc tgctcatttc ctgtaggata aattctagtg agctgttgag
     3421 gtgctcatgc gtaataaggg tgatttgctc gtggtcacga tttttcatgc cacgataaat
     3481 catccaatgc tcagataaag cgcgttttcg tctttctagg gaagagatcg aaatttttct
     3541 aaagtaaaca aggtaggtct gcaattcagt gacaatttct tttaatctga ccatctgact
     3601 atagctgtaa atcagattat taaagctgtt gaaattatct agaattctgt tgagatcgtc
     3661 atcttctata aaggtttcac aatcagccaa caaatcatgc atgacctgaa aatcttcctc
     3721 tgtcatcaaa tacatagcgg tgcttgttgc cagtgtttca agcgcttttc tgatttcaaa
     3781 gatttcacaa gcatcttgaa tactaacacc cttgacaata atgccttttt taggaatatg
     3841 ctctaccaaa tgctcctctg ataacaatcc tagagcgtac ctgattggtg ttctgctaat
     3901 atttagggca atggaaaatt ctttttcgtt gatacgactg ccagcaggaa tttgtcttaa
     3961 aataatagtt ttctttaggg cgttataaaa agctattttc aaagggatat tgcgggatag
     4021 gtcaagatta ttctttactg cttcgataat aggattcata taatctcctt aatgttcata
     4081 tcatgatatt attatactga aaatcattac taatgaaaat aataattagc ctcctaaaag
     4141 gcgaaagcca tgctcgtgaa agaacatggc tttcattagc ccacactaca gtcctaataa
     4201 tagctcgtga cctattgtgg aatgtaaagc ggcatttgtc ccattgcaat aatggttaca
     4261 acaaagataa taaagataat aatcgcgtat ttagcagctt ctttttgcca ttctcccata
     4321 tcaagcccag taagacgaag aagcaggtaa ataaaggcca ccaatggact gagcaaatgg
     4381 aaggcttgtc ccatcagaga agcaagagcc atcgccatgt tgctaaagcc atattcagct
     4441 ccagcctccg ctaagactgg caaaatacca tagtagaagc catcatttga gataaagaaa
     4501 gtaccaggag ctgaaatcag ggcaataaca agtccccaga agccagccaa ttgctttgga
     4561 ataatcgttg caaagctttg agcaagagca ctagccatac cagagccttg gaaaagtccc
     4621 atgaagatac cagcagcaaa aaccagaata acaacctgaa cagcatcacc ggcattatca
     4681 ccaatacgct ttgtttggtc ctttaggaca ggatagttaa caataagggc aatacaggtt
     4741 cccactgcaa ataaaagaag tggtgccata gcaatagcct tatagaaaga gccagcaacc
     4801 agccaagtga ttaagccgat ggttaagata gcattaaagg caaagttttt aggacgacgg
     4861 atagaaagcg tatctggatc tgtaatgtct gttagcttac gcatttcctc ttcggtcaaa
     4921 tcaacaacac caagtcttgc acgctccttg cgtcccatgc ttggcgcaac ccaacaaatg
     4981 acataaagaa gagacaaaac cataccaggt gcaaggtatc caaggatttc aggtcccaca
     5041 ctaagcacag acatggcacg cgcagttgga ccaccccaag gaagcaggtt catgatagtg
     5101 ttttgcagga taatcaagac accaagattc atgatgcgca tgtttaattt cttatagatt
     5161 ggtaaaaaag cagagcagca aatcaaggtt gttgttgtac catcaccatt aagtgaaaca
     5221 gctgctgcaa caattgcagt tgccatcaag accttcatcg ggtctccctt agcaaagcga
     5281 atcatttttt cagtaatcgg gtcaaacaag ccagcatcta gcataatgga aaagaacagg
     5341 atcgcaaaaa gcagcataat acctgtctta gcagtgttat taataccgta catgatcata
     5401 ggaccaatag ctgtcagatt tttagcaagc ccatcctcac caacaaaggc aacaaatttg
     5461 gcgtctgatg taaaatcagc agagcctgtt aatataacag caattgtcat tatcaacgga
     5521 atcatgacca gagctgtaaa aggggtcatt tttttcttca tgacgacata catgaagata
     5581 ataatcatag cataagctag aactgttaat aacatattgt tatctccttt ttgattttat
     5641 gacttcagta taaatgaaag cgttcgcaaa agaaatacct ccatgtacgg aaaaacacaa
     5701 aaaaaacatt ttgaaagcag atcctgaaaa aataaatggt tacattaatg tttttcaaca
     5761 gcagttagtt gctcttatct tcagtaatcg cagtgtgttt cagcattttt taaaatcagt
     5821 catatttatt ttagttaact gtttttataa aaatggttaa ctaaaataag aaaatccttg
     5881 aaaatgtgaa agcgctctta gaaagaacac aaaaaagcca ttccaaaagg atgaggtggt
     5941 atataataag catagaagct tcccatttgt gggcaaacta agaaaggagg tagcttatgc
     6001 agttttttca aaacatgttt agacgctcta aaaaagaggc agccacaagc catcaagaca
     6061 gagaaaataa gcctgaattt ccgttagatg actgggagcc agtgcctagc tacattgctg
     6121 cagataaaaa ggattatcag acagttagtc tgattgccag tgccattgca gctggcgagc
     6181 aagctagcag tcagtttaag gtaaaacgaa tcctacagcg caatcctgag gccttaaccg
     6241 tatccttaat agcatcaagc attgcagctg gtgtttatcc agagagtcaa tttctggtta
     6301 ggtccattta tagtaagaaa gtaaacgtta gccacaaata gtaaaaggag aaaagattat
     6361 gttgcgtaag tttaaaatta ccattgacgg aaaagagtac ctagttgaaa tggaagaaat
     6421 cggtgctccc tcccaagccc cagtagtacc tcctgttcaa ccagcagtag ctccagcccc
     6481 tgtagccgaa aaaaaggcag cagaagctcc gcaagctcca gcagcacctg tatcagcagg
     6541 ggcagatgca atgccctcac ctatgcctgg tattatctta aaggttttag ttaatgttgg
     6601 tgatgtcgta catgaaaatc agcctctatt gattttagag gctatgaaaa tggaaaatga
     6661 gattgtcgcc tcaacagctg gtacagtcac agggattcat gttactgcag gtcaggtggt
     6721 caaccctggt gaaggcttaa tcaccattag ctaatcctaa gtcgtgtctt gatttaaaat
     6781 gttgtagaaa aggaagtaca tttgtggaaa cattaattgc aggagtaacc tccatcacta
     6841 ttcctcaaat cattatgatg cttatcggtg ctgtcttaat gtatctagga ataaaaaaag
     6901 aatacgaacc aaccttacta gttcccatgg gactgggtac tattttagtc aactttcccg
     6961 gcacaggagt cttaacacag gttgttaatg gtgttgagca agaaggggtc tttgatgcct
     7021 tattcaattt tggaatcggt acagagctgt ttccattact tatttttatc ggtattggtg
     7081 ccatgattga ctttggtcct ttacttcaaa atcctttcat gctattattc ggtgcggcag
     7141 ctcaatttgg gattttcttt gttgtcgttg tagccgtatt agctggcttt gatattaagg
     7201 aagcagcttc aattggtatc attggtgctg ctgacggtcc aacatcaatt tttgtagcaa
     7261 accaattggc aaaggatttg ctagggccta tcacagtggc agcttattct tacatggctt
     7321 tggttccgat cattcagccc tttgcgatca agctagttac taccaaaaaa gagcgtcgta
     7381 ttcgtatgac ctataaggct gagaatgtgt cacaattaac gaagatcctc tttcctattg
     7441 tgatcacact tgtagccggc tttattgctc caatttcgtt accattggtt ggttttttga
     7501 tgtttgggaa cctgcttcgt gaatgtggtg tcttggaccg attgtcacag accgctcaaa
     7561 acgaattggt caatatcatc agtattttac taggactaac catctctatc aaaatgcagg
     7621 ccgagctttt cttgaatgtg caaaccctgc ttattatcat ttttggtctg ttggccttta
     7681 tcatggattc gattggtggt gtgatgtttg ccaaattctt gaatttattc cgtaaggaaa
     7741 aaatcaaccc aatgatcgga gctgctggaa tttcagcctt tccaatgtca agtcgtgtga
     7801 ttcaaaaaat ggccactgat gaggatccgc agaatttcat cttgatgtat gctgtgggtg
     7861 ctaatgtatc tggtcaaatc gcctcagtta ttgcaggtgg cttgctgctt gcttacttta
     7921 gctaagaaag gacgtgctta tgacaatcaa tatagaccat ttgatccaat cctttgagct
     7981 aatggcactt ggaatggcag gagtatttgt tgtattagga attctctata ttgtagcaga
     8041 ggctctgatt aagctatttc cagtagaaaa ataatagaat atgatctaaa caaggaggtc
     8101 aatcaaatgg agatcaaaca aattgctgtt gctggttcgc ttgaatctag cgacatgatg
     8161 ataacaatat cacctaatga tggtcaggga atcgttttgg aattggattc aagcgttgaa
     8221 aaacaatttg gcaatcatat cagagcatta atcaagacaa cacttgccag gctgggcgtt
     8281 gagtcagcaa cgatcgaagc tgttgataag ggagccttgg attgtaccat tcaggcaaga
     8341 acaattgcag cagtccatcg tgctgctgga gttgagcatt acaactggaa ggagatcgac
     8401 tcatggaacg cttaagaaga acgatgatgt ttgttccggg cgctaatgcg gctatgctaa
     8461 gagatgcacc cttgtttgga gcggactcta tcatgtttga tttagaggat tcagtttcct
     8521 taaaagaaaa agacacctct cgcgcccttg ttcattttgc cctaaaaacc tttgattatt
     8581 caaatgttga gacagttgtg cgcgttaata gcctagactc ttgtggtgct ctggatattg
     8641 aggcagttgt gttagcaggt gttgatgtta ttcgcttgcc aaagacagaa actgcccagg
     8701 atattattga tgttgaggca gtcattgagc gtgttgagcg tgacaatggg attgctgttg
     8761 gtcgtacacg catgatggca gctatcgagt ctgcagaagg ggtcttaaaa gctcgtgaga
     8821 ttgcaaaggc ctcaaatcgt ctcattggta ttgccctcgg cgcagaggat tatgtgacta
     8881 atatgaaaac acgtcgctac ccagatggac aagaattatt ctttgcccgc agcatgattc
     8941 ttcacgcagc acgtgctgct gggattgcag caattgatac cgtttattca gatgtcaaca
     9001 atacagaagg cttccaagct gaggtgcgtc atatcaagca attaggcttt gatggtaaat
     9061 ctgtcatcaa ccctcgtcag attccattgg taaatgagat ttatacacca accgaaaaag
     9121 agattagtca cgccaagcaa gtgatctggg ccattcgtga ggctgaaagt aagggatcag
     9181 gtgtcatttc attaaatgga aaaatggtag ataagccaat cgtagagcgt gcacagcgtg
     9241 ttatcgcttt ggcaacagct gctggggtat taacagagga ggacatttag catggttaaa
     9301 aataaacttg gtcgtgatat tcctcaggag tatgctgatc actatggagt atttgaagga
     9361 gagctagcac gtatcactag ctacaatgaa tcaagccgcc gcattaagcc tgtaaagcca
     9421 ggtgacagta aattgcttgg ctctattcgt gaagctattg aaaagacagg cctaaaagat
     9481 ggcatgacca tttcatttca ccatcatttt cgtgaggggg acttcgtcat gaatatggtt
     9541 cttgatgaga tagccagcat gggaatcaaa gatttagcta ttgctccaag ctctattgcc
     9601 aatgtgcatg agccattaat tgagcacatt aaaaacggag tggttacaag cattacctca
     9661 tcaggtttac gtgataaggt tggggcagct atttcatcag ggattatgga aaagcctgtt
     9721 gtgattcgtt ctcatggagg acgtgctcgt gcgattgcta gtggtgatat tcatattgac
     9781 gttgcctttt taggagcacc aagctcagat gaatatggta atgtcaacgg tacgattggt
     9841 aaggctacct gcggctcact tggctatgct atgatcgatg ccaagtacgc agatcaggtg
     9901 gtggtgctga cagatcacct agttgattat cctaacaccc caattagcat tccgcaaact
     9961 gatgttgatt atgtcgtgac agttgatgct attggtgatc cacaaggaat cgctaaggga
    10021 gcaacgcggt tcaccaaaaa tcctaaggag ctcctaattg ccgaatatgc cgctaaggtt
    10081 atcacacagt cgccttactt taaaaatggc ttttccttcc aaacaggtac aggaggagct
    10141 tccttagcag tgactaggtt catgcgtgag gccatgcttc aagaaaatat caaggcaagc
    10201 tttgcccttg gaggcattac aaacgctatg gtagaattgc tcgaagaagg attagttgag
    10261 aaaatcctag atgtacagga ttttgattac ccttcagcag tttcgcttgg taaaaatgct
    10321 cagcattacg aaattgatgc taacatgtat gcctcaccac taagcaaggg atcggttatc
    10381 aatcaattag acacctgtat tttatcagcg cttgaggttg acactaattt caatgttaat
    10441 gtcatgacag gttctgacgg tgttattcgt ggggcttccg gagggcattg tgacacagcc
    10501 tttgctgcca aaatgagtct ggtgatttca ccccttatcc gcggacgcat tccaaccttt
    10561 gtagatgagg taaatacagt aattacacct ggaacaagcg ttgatgtggt tgtcacagaa
    10621 ataggtattg ctatcaatcc aaaccgtcca gatttgatag agcatttcaa ggacttgaag
    10681 gttcctcaat ttagtatcga agaattaaaa gaaaaggctt actcgattgt tggaacacct
    10741 gatcgtatcc aatacggtga taaggttgta gctcttattg agtatcgtga tggcagcctg
    10801 attgacgttg tctacaatgt ctaaggaatt gattttcaag gggaaagctg ttaccctagc
    10861 tgatatgcta agggcacgcg aggacagaag ccttcgtcaa ggaaagcttt taacagaatt
    10921 ctcaaacgaa agcctgcttt ctgtgaccat gaatattcca ggccccatta aaacgtcacc
    10981 tgctttactt gaggtatttg atagtgttat caaggcaatc ctagaaaagc tgtctggcaa
    11041 tcagatcagc tatcagcttc gtttgctgcc aaaaacgggt tatgaatatt accttgtgac
    11101 agccttagat agtcaggcat taaagctcaa aatgattgag cttgagactg atttaccgat
    11161 tggcaggcta atggatttgg acgttttagt gctgacaaat cagctgccaa cccctatcag
    11221 tcgaacagcc ttaggctttc ctcctcgcag ctgctatctt tgctcaaaag aggctaaggc
    11281 ttgtagtaga aatcgcagtc actcggtagc agacatgcag acagcccttg tacacttact
    11341 ccaatcattt tttgacggag gcaatcagct cagttagact caacggtatt cttataagga
    11401 gaatgatatg acaaaaatcc gtataacaga aacagttttg cgtgatggtc agcaaagtca
    11461 aattgctacc cgcatgacta caaaggaaat gattccgatt ttagaaacac tagataatgc
    11521 tggctatcat gccctagaaa tgtggggagg agctaccttt gattcttgcc tacgtttctt
    11581 aaatgaagac ccttgggagc gtctaagaac cattcgtaaa gtagtcaaga aaactaaatt
    11641 acaaatgctc ctgcgtgggc aaaatctttt gggctatcgt aattatgctg acgatgtcgt
    11701 ccgcagcttt atccaaaaat caattgaaaa cggtattgat attgtgcgca tttttgatgc
    11761 cctaaatgat ccacgtaatc tagagacagc tgtttcagca acaaaagaat tcggtggcca
    11821 tgcacaggtt gctatttctt acacaacaag tccagttcat actatcgatt attttgtagc
    11881 cttagcaaaa gcctatcagg ctattggtgc agattcgatt tgtatcaagg atatggctgg
    11941 tgtgttaacc ccggagaccg gttatcaatt agtgaagcgt atcaaggaaa gcattgctct
    12001 accacttgag gttcacacgc atgctaccag tggtatttct gaaatgacct atctcaaggt
    12061 cgtagaggct ggtgcagata ttattgatac tgccatatcc tcatttgccg gcgggacaag
    12121 ccagccagca acagaatcga tggttattgc tttagaggac ttggggattg ataccggagt
    12181 agacatgaca aggctgacaa aaattgccga gtattttaat actatccgag atcactacag
    12241 ggcagagggc attttaaatc ccaaggttaa agacactgag cctaagacct tgctttatca
    12301 ggttcctggc ggcatgctgt ccaatttgct aagtcagctt aaggaacagg gactctctga
    12361 caaatatgaa gaggttctgg ctgaggttcc aaaggttaga gctgatttag gctacccccc
    12421 actggtgact ccgctatcgc aaatggttgg cacacaggcc ttaatgaatg ttatttcagg
    12481 tgaacgctac aaggttgtcc caaacgaaat caaagactat gtcagaggac tttatggcca
    12541 acctcctgcg ccactaggtg aaggtattaa agagaaaatc attggtgatg aagctgttat
    12601 cacttgtcgt ccagcagatt tgattgagcc acaattgccc ttgcttcgtc aagaaattgc
    12661 aggctatgcc tgctgtgagg aggatgtgct gagctatgcc tctttccctc agcaggcaaa
    12721 ggatttccta ggacgcagag aggatccctt ttatgatatc ccagttcagt acgtcaccgt
    12781 tgatatagca atggattaat caaaagaata aaaagcaaga taactaataa aatcaatctc
    12841 ctaattatta gtcaaagcta cctaccaata aactccttaa tcagaaccac ccgtctaatg
    12901 aggtgccccc aaaaggttag tccaaaactt taggctccat gtcaactgta gtgggtagtt
    12961 gacaagctaa catctggaga ggac
//
LOCUS       DARYXZ010000056        12767 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYXZ010000056 DARYXZ010000000
VERSION     DARYXZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12767
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..274
                     /locus_tag="TV186_001681"
     CDS             <1..274
                     /locus_tag="TV186_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEL1533052.1"
                     /translation="REYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAY
                     IKSTGKTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            271..1045
                     /locus_tag="TV186_001682"
                     /pseudo
     CDS             271..1045
                     /locus_tag="TV186_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            1042..1527
                     /locus_tag="TV186_001683"
     CDS             1042..1527
                     /locus_tag="TV186_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1533053.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            1524..2995
                     /locus_tag="TV186_001684"
                     /pseudo
     CDS             1524..2995
                     /locus_tag="TV186_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001899253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            2949..3305
                     /locus_tag="TV186_001685"
     CDS             2949..3305
                     /locus_tag="TV186_001685"
                     /inference="COORDINATES: protein motif:HMM:NF014581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HEL1533054.1"
                     /translation="MERKKTLKELSETLGKETIDLYNTSETRSNQKSFGLNYQKTGKE
                     LMSQDEITVMDGGKCIFQLRGVRPFLSDKYDITKHKNYKLLEDYDKKNLFDIESYMKR
                     KGKAKLNRETVITRMQ"
     gene            3469..3780
                     /locus_tag="TV186_001686"
     CDS             3469..3780
                     /locus_tag="TV186_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1533055.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            3784..3999
                     /locus_tag="TV186_001687"
     CDS             3784..3999
                     /locus_tag="TV186_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1533056.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            4019..4885
                     /locus_tag="TV186_001688"
                     /pseudo
     CDS             4019..4885
                     /locus_tag="TV186_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4905..5168
                     /locus_tag="TV186_001689"
     CDS             4905..5168
                     /locus_tag="TV186_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1533057.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            5172..5561
                     /locus_tag="TV186_001690"
     CDS             5172..5561
                     /locus_tag="TV186_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1533058.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            5473..7902
                     /locus_tag="TV186_001691"
     CDS             5473..7902
                     /locus_tag="TV186_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1533059.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            7906..10029
                     /locus_tag="TV186_001692"
     CDS             7906..10029
                     /locus_tag="TV186_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1533060.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            10042..10281
                     /locus_tag="TV186_001693"
     CDS             10042..10281
                     /locus_tag="TV186_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1533061.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            10256..11803
                     /locus_tag="TV186_001694"
     CDS             10256..11803
                     /locus_tag="TV186_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1533062.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            11899..12675
                     /locus_tag="TV186_001695"
                     /pseudo
     CDS             11899..12675
                     /locus_tag="TV186_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
BASE COUNT         4833 a         1872 c         2816 g         3246 t
ORIGIN      
        1 gagagaatat aattttagtg aaaacgggct tggaacattt caaaatgtgt ttttagctgc
       61 tgaagatata tcagacttac aaatcataat gaactcacag cttgataatt atattgagag
      121 attatctgca tatattaaaa gcaccggaaa gacctataaa gaccataagg caacaatcct
      181 ttcatggttt tataaagatc agggaagggg caaagaagtg aaaacatcaa atatcccgac
      241 atgggaagaa tatgataaag gagaacacct atgataaaag aattagaaaa agtaatgata
      301 gaggatgtag agtattctta cgatcctgaa aaagaatata tcaaggacgg acacgccttt
      361 tgtaaagttt gtcatgaaag aaaagacaga aaagtgatgg agttctttga taacaagatg
      421 atatttaaga tttcttgcaa atgcgataga gatagagagg caagaaaaaa agaaagagaa
      481 aagcagatgg aaatagaacg attaaaaaag aactgcttta actctattat tcagtggtca
      541 tacacctttg aaaattatca gggagaagaa aatcaaagtc ttatcattgc aaagaatttt
      601 gtaaaagact atgagcagat gaaaaaagaa aatatcggac tgctatttta cggctcagta
      661 ggaagtggaa aaacctatct tgcctgctcc attgcaaata gccttattga acagtatcaa
      721 ataggcgtta aaataagaaa ttttgcacag cttatcaatg agctgcaaaa gggaggattt
      781 gattttgata agaacgcata tattgaatcc cttgtaaata cttccgttct tatcttggat
      841 gacttgggaa tagaaagaga tacaagctat gccaaagagc aggtatataa cattgtcaac
      901 aacaggtact taaagcagaa accgactatc ttcaccacta acctttccta cgacacaatc
      961 caaagaggat tttagaaaga ttattcaaag agataaattg aatcgaaata aagataggtt
     1021 actgaatgga ggtgagagaa cttgatcaat gaagaaatag caagaaaaac gctgaatatg
     1081 gaagtaagag ctgctaaagt aacaggaaag ttaattctga acttattaaa gaaattgatg
     1141 aaagaagcag aaaaacttgg aggacttgaa aagctggtta atgctaacgg aaatgaagta
     1201 aagctaaaag atatggtaaa aaagggacag cttgaagaaa ttcctgttga agaagcggag
     1261 cttaaggaac tgaaaaaaga acttaatcgg tatggtgtta agttttcagt gatgaaggat
     1321 aaggaaacag gaaaatactc tgtattcttt caagccaaag atatgaaagt gatggataaa
     1381 gcctttaagc acgcattagc acagtctgaa aagaaaacgg aaaggaaaga atctattcac
     1441 aagaatattg agaagtttaa ggaaatggct aagaactctg tttccaaaga taaaatcaag
     1501 aataaacaaa aggagcagag cctatgatag ataaaatatt aaaggacatc aaaggcttat
     1561 ttaaggtgca ggataagaca aagtttgtaa agcaaaacat tccctatctt gcatttttct
     1621 atttaggaaa catctttgcc catcatgtga gaagctatac cggtggtgat gtcatagata
     1681 aaatctttca agggatattg gagatcaaca cgatgagttt tcttccaagt attcatccgg
     1741 cggatatttt aatgggcata ggaatggctg ctttaattaa atttattgtc tataccaaag
     1801 gtaaaatgct aaaaagttta gacaggggaa agagtatggc tcagcaagat ggggaaataa
     1861 gaaagatatt gagccataca tggatgaaaa gtttcaaaac aatatcttgc ttacccagac
     1921 agaacgccta actatgaatg gtagaccggc taatccaaag tatgctcgta acaagaatgt
     1981 acttgtaatc ggtggatcag gaagtggtaa gacaagattt tatgtaaaac cgaaccttat
     2041 gcagatgcac agtagctatt gcgtaaccga tccgaaagga acgatagtca ttgaatgtgg
     2101 caagatgctt gaagacaatg gatatgagat aaaaattcta aataccataa acttcaaaaa
     2161 gagcatgaaa tacaatccct ttgcctatat ccattctgag aaagatatac tcaaattagt
     2221 gcagacaatc attgcaaata caaaaggtga gggagaaaaa gcgggtgaag atttttgggt
     2281 caaagcggaa aaactctact acacagcact tatcggatat atcttctatg aagctccaag
     2341 agaagaaaag aactttgcaa cgctccttga tatgatagac gcttcagaag taagagaaga
     2401 tgatgaaacc tatatgaatc caatagacag actctttgaa gcacttgaga aaaaggagcc
     2461 tacgcacttt gcggtcaagc aatataaaaa atataaattg gctgcgggaa agacagcaaa
     2521 atctattctt atatcttgtg gtgcaaggct tgctccattt gatattcagg aacttagaga
     2581 tttgatgagt gaagacgaac ttgagcttga tacattggga gatagaaaga cagcactctt
     2641 tgttattatc tctgatacag atgatacctt taactttgta gtgtctatta tgtattcaca
     2701 gttatttaat ctactttgcg ataaggcgga tgatgtatat ggtggcagac ttcctgttca
     2761 tgtaagatgc ttacttgatg agtttgcaaa tatcggctta attccaaagt ttgagaagct
     2821 catagccaca attagaagta gagaaatttc agcgagtatt atcttacagg cacaatctca
     2881 gctaaaggca atatataagg ataatgctga taccattgtg ggtaactgtg atagtacctt
     2941 attcttaggt ggaaaggaaa aaaacactaa aagagctgtc cgaaacgctt ggtaaagaaa
     3001 ctatcgacct ttacaacaca tcggaaacaa ggtcaaatca aaagagcttt ggacttaact
     3061 atcaaaaaac aggcaaagag ctgatgagtc aggatgagat tacggtcatg gatggtggaa
     3121 aatgtatctt tcagcttaga ggtgtcagac cttttctttc agataagtac gatattacaa
     3181 agcacaagaa ctataagctg cttgaggact atgataagaa aaatttattt gatatagaaa
     3241 gctacatgaa acggaaagga aaagcaaaac tgaataggga aacagttatt acaagaatgc
     3301 agtaagtcta caaaatagat ttgctgcttt tttatgcaaa agtaaggagg caagatgata
     3361 aggatcagaa gtcccactga gtaaaaaact aaatagtatg agtatagcga ttggaaaagt
     3421 aatacttccg gtcgcttttt ttattgaaat gaaaaggaga aatttttaat gaagcaagaa
     3481 atgattaaca tcaacgccaa cttagtggca gaacctactt tctcaagttt tgaaaaagag
     3541 ggtaaagaag tagaagttgt aaattttacg cttgtaaaga agtacggtaa aggcaaggag
     3601 tacatcaatt gtgcagccta tggagaaaaa gcggataaag caaaggactt tgaaaagggc
     3661 gatttgattc atgtattcgg ctactttaag aagcgtgaaa aagagggaaa gacttacaaa
     3721 aattttgtag tgaagtcata caacaagatt gaaaagaaag aagaaaatga ggaggaataa
     3781 attatggaat ttttcgcaca ggcagtaaat gtattaaaga ttttggttat ggcagtagga
     3841 gcaggacttg gagcatgggg tgtcattaac ctgatggaag gttatggtaa cgataatccg
     3901 ggagccaaaa gtcaagggat caagcaattg atggcgggag gaggtattgt ccttatcgga
     3961 cttaagctga ttccacttct tgcaaatgta ctcagataag aagaaaagga gagcttagat
     4021 gtttgggata ttcgacaaaa tagaagaatt ctttaaggag cttctactgg gcggtatcca
     4081 agcaaactta gagtccatgt ttcttgacat caacgacaag gttggtgcag ttgcaacaga
     4141 tgtaggaaaa actcctatgg ggtggaatgg agatgtattt acctttatta aaagcattaa
     4201 cgattcggtc attattccca tagcgggact aattatcaca gcagtccttt gtatcgagct
     4261 tatcaatatg gttatacaga aaaataacct acatgataat acggatacat ttgaattttt
     4321 caagtacatc atcaagatgt gaattgctgt atggttggta tctcacgctt ttgaattttc
     4381 aatggcggtc tttgatgtag cacagcatat ggtaaataag gcggcagggg tgataaacac
     4441 ctctgccacc gtttccggag atcagatagt ggcgatgatg gataccctaa aagaaaaggg
     4501 acttggagag cttatcatga ttctctttga aacctcgctc attaaagttg ccatacaggc
     4561 aatttccata gtgattatgc ttgtggttta cggaaggatg tttgagattt atgtttattc
     4621 atcggtttca gccattccat ttgccacgat gggaaacaaa gaatgggggc aaattggcac
     4681 aaattacatc aaaggattat ttgcacttgg actacaagga ctctttttaa tggtttgtct
     4741 tggaatttac gcagtattag ttaagacgat tgaaataaca gatatacaca caagtaccat
     4801 gacgatactt ggttatgcgg ttttgctggg gttaatgatg ctaaagagcg gaacactggc
     4861 caaaagcgta ttaaatgcac actaaaaaag aaaggaaaga tagtatgaat aaaagaaaaa
     4921 cagtatttac agcagtagta atggtcgcag gcattatggc ggtaattgat agaatcaggc
     4981 ttcataacaa agctgccgaa ttagaagaaa gaacacagga catcggtcgc tgccataatg
     5041 atttttgctt aatgcagcaa agatataaca agaatacaga tgaacagctt gcaattattc
     5101 aggatgaaat cggctctgta tatgaacact ttgaggagtt ttcaaagggt aaagaagatg
     5161 ggaggtaagc tatggcgtat gtaccaatac ccaaggactt aaagaaggtc aagacaaagg
     5221 tagcctttaa ccttacaaaa agacagctca taggatttac cattgcagga cttgttggaa
     5281 tacctgtcta tttatttatg agaaaggtag taccaaacga tatagctttc atattcctta
     5341 tcgtgtccac acttccaatc ttttttatca cactttttga aaaggacgga ctgacctttg
     5401 agaaatattt taagcatatc taccttcata agttttatca gccggcaaag agagtgagaa
     5461 aggaggttta ccttgaacaa gaaaagaaaa attcagcaac taaagttaga agaaaacaaa
     5521 aaggcattaa aaaaggagag aaaggactta aagcaaagta agggaaagtc taacaaagaa
     5581 aagagcggac tacttgatct tatctttaga aaagagcaaa aacgctatac ggtagaagat
     5641 accattccct atcttagact cttaaaaagc gggatatgcc agctcgatga aaagcacttc
     5701 agtaaaagca tagcctttca ggacattaac tatcagcttg ctttagatga agatagggat
     5761 ttgattttta atcagtttgc aaactttcta aattcctttg atccaagcat agcgattgag
     5821 ttttcctaca tcaatcagct tggacgaaac gaagaaatga aatcggcaat tcagataccg
     5881 gataaagggg acggatttga cgatatacga cttgagttta gagagatgct aaaaagtcag
     5941 attgtaaaag gaaataacgg actgaaaaaa tcaaagtatg taacctttac agtagaggca
     6001 gacaatttag aacaggctac atcaaaactt gaaagattgg atatagatat attatctaat
     6061 ctcaaaagca tgggggtaag agctgaaagt cttacagtag aggaaaggct aaagattctt
     6121 cacgatatat taaatccgaa taagaccttt gagttttcct acaaagacct gaagaaaaag
     6181 gaaagtacca aaacatatat cgtgcctgat gaatttaact ttatgccaag caggtatttc
     6241 aagtttggga agtttatcgg agcaacaagt cattttcaaa tccttgcaag tgagctttca
     6301 gaccgtatgt tatcggagtt tttggatatt gatgataaca tcaatatatc ttttcatatt
     6361 aaggcgattg accagtcaga agccatcaag atggtaaaac gaaaaaacac cgatattgat
     6421 aagatgcgaa ttgaggaaaa caagaaagct gtaaggtcag gctatgacat ggacattctt
     6481 ccaagtgatt taattactta cggagaagat gtaaaaagtc ttttaaaaga tttacagaca
     6541 agagatgagc gtatgtttgt tgtaagtatt gtctttatga attttgcaag gacagtgcaa
     6601 aagctcgata acaccatagc tcagataagc tccattgcaa acaagcataa ctgtaaattg
     6661 aaaagacttg accatacgca ggaacaaggc ttagtgagcg tgctgcctct tggggtaaac
     6721 aagattgaaa tagatagagg gctaacctca tcatcaacag cagtctttat gccttttaca
     6781 acagaggagc tttttatcaa ttcaagtaat agcctatact atggactaaa cgctttaagc
     6841 cataacctga ttatggcgga tcgaaagaaa ttaaagaacc caaacggtct aatcttagga
     6901 actccgggta gtggtaagtc ctttagtgcc aaaagagaga tggcaaatgc gattttagta
     6961 acggacgatg atgtgattat ctgtgatccg gagggagagt atggaaacct tgtaagacag
     7021 tttaatggag aagtcattaa ggtcagcagt aagtcaaaag attacctgaa tccacttgat
     7081 ataaatatga actacggtga tggggacgca cctcttaaag acaaggcaaa cttcattatg
     7141 tctatgcttg agcttgtagt tggtggtagt ggacttacag cggaagaaaa gtccgttata
     7201 gatagatgct tacctaagat ttacgaaagg tactttgaaa atccgactta tgacaatatg
     7261 cctatacttc aagacctata cgatatgtta aaagggcagg aagaaaaggt agggaaaaag
     7321 ctggcaacag agatggaaat ttatgtttca ggttctctta atgtctttaa tcacaggtca
     7381 aatgtggact taaataagaa gctactttgt tttgatatta aggagcttgg aagtcaatta
     7441 aagaaaatag gtatgcttgt tatacaggat caggtgtgga ataaggtatc gcaaaacaga
     7501 ggaaacaagg ctacaaggta ctatatagat gagtttcact tgctgttaaa agatgagcag
     7561 acagcttcat attcggtaga gatttggaag cgttttagaa aatggggagg aatcccgact
     7621 ggtatcacgc aaaatgtcaa agacctactt atgagtaagg aaattgaaaa tatctttgat
     7681 aatacggact ttgtcttaat gttaaatcag gcttcgggag atagggaaat acttgcaagg
     7741 aaacttaaaa tctcacttcc gcagcttaga tatgttacga actccaatga gggcgaggga
     7801 ctacttttct ttggaaatac cattgtgcct ttccttgata agtttccgaa agatacaatt
     7861 ctttatcaga agatgactac caagcctgaa gaagtgaggt agcttatgga tgggaagctg
     7921 aaaaaagatt ttagagaaag gcataaggca agccttgaaa gggagatgct taaagctgaa
     7981 acaagctcta tacctgaaga aagtaagcta aagcataacg atgattacag aggaaaaatt
     8041 gtccatgaca aagatagatt tcaggacaag gttcatgaga agataagcaa ggtaagatct
     8101 gaaaatgagc agatagaggg gacttctaaa agaaatgcaa agtatagggc ttctgataag
     8161 ggaagtgtaa atgaagcagg aaaggctgac tatgatactg aggtaaagaa cgggaaaatc
     8221 tatgattctt taggacaaga ccttgataat gatggaatca tagacagata cgataatgat
     8281 tttagggaca gcgactactt tgaatcaacc tatgatgtag aggataatct acctcaaaaa
     8341 gaaaaatcat tagaaaatcc ctctaaaaat cataaggctc aaaagaataa gtataaaagg
     8401 aaaaactatt ccgaaagcct ctatacaaga aaaaaggacg atgtaccaaa agagaataag
     8461 cctgaagata aaaaggcagg gaaagatgtt gcgggcgaaa aagaacatag cagtctttca
     8521 aaagaccaaa agaaaaagct gaagaaagat atggtaaaag tatctgccct gtcaggactt
     8581 gccaaaggaa gtgaaaccgt aagagattac ctttctcatg gaagtgatga aaataaaggc
     8641 gtagaagcgg gagaaaaaac agccgatgca agttcaaaac tcattcatgg tataaagaga
     8701 tactcagata agaaaagagc taaaaaagga tatgagctta caaataagga ctataaaatc
     8761 agaaagcgta aatccaagtt agagtttcgt gatgccaaag aggaactgaa aaagacagat
     8821 gagtataaaa gagcaagtgc ctataaaaga tttcaaaaga aaaatcaggt aaaggcagcg
     8881 atttctcgtg agaataagtc aagactcaga gatcggatta aagagggact tatcggaaca
     8941 ctgaaaagct caaaggatat gattatccga aaagccaaag gactaatgct tatcttcgta
     9001 ggtatcatca tcttaggaaa ttttgtgatt aactttgcag gaacaggcat gacaggcttt
     9061 atgaactcta caaactctgt tcttacaaca agctatttat caaagccaaa tgttctaagt
     9121 gaaatcaatc agaagttttc tgctatggag agtgagcttc aaagtgaagt ggatcatgta
     9181 gaagagaatt atcccggata tgatgagtat atcttaaaca acacagagta tatcggtcat
     9241 aatgtccatg agcttttatc ctacattaca tcaaggtgcg gagaggtaaa gagtgtatcg
     9301 gaagtagaaa ccatattaaa agaattgttt gagtccatgt atgaccttga atacagggaa
     9361 gaaattgaaa tcagatacag gacagttaca gaaacctata ccgatgaaga tggcaatgaa
     9421 tataccgaaa gccatgaaga gccttatgaa tataagaagc tcattgtaac gcttcataaa
     9481 aaagagatgg acagcattat ccgaagggtc tttaaagact atcccgataa tttaaagcac
     9541 tatgaagcct tattccttgc tcaaggaaat atgggagaag cctttagaaa ttctgacctt
     9601 atcagtgcta atggcggtgt aggtggtggg aaagagtatg aggcatcttc ggaagtacaa
     9661 aagaagattg ttaatgctgc atatatcact ccatctccgg gtgcaggctg gtgtgccatg
     9721 tgggtatcgc aagtttacca aaatgcggga cttggatata tcggaggaaa tgctaatgat
     9781 atgtatcgaa actatacctt tacatccgat aggtcaaagc tcaaggtagg aatgcttgta
     9841 gcggtagaaa gcagcagtag cggaagcaca gcaggactta cctatggtca tgtcggaatc
     9901 tatatcggag acggcaaggt tattgataat atcggttata taagagtaac tactttagat
     9961 gattggattg cgactttttg taaacaccat ccggtaggct ttggttttcc accaaatgta
    10021 aacagataag gagggaacaa tatgaaaaaa gaactgacag cagtaaaaaa cagaataaaa
    10081 aagttaaagg ataaaaaggc tctgattgat gaagaattgg agcctttatt tattcgtgaa
    10141 gaagaacttg aaaatgaaga aatcatcatg atttgcagaa agaacaacat cacaatttct
    10201 gatttaatga caaaggtaaa cagagaaaaa gcagaactga aaaaggagag gacaaatgaa
    10261 aaccagtttg aaaaagaata ataagttttg gacagcagca cttgcagtaa ttgtaagtat
    10321 tagctgcatt ttaggacttt ggacggttgt ttacgccaag gagaaaagct ctgacgctcc
    10381 tacaaaaaac gaagctgtcc aaacggaagt tgaagtaaat gtaaagtata tctttgaaga
    10441 tgaaaaggta tttaaggaag aaaagattaa ggcagagaaa ggacagcttc ttgatagtgg
    10501 cgatcttcca atgctccctg atgatatgaa atttattgat gaattcctgt tttatgaagt
    10561 aaagggagat ggaaatgatg aaattatccg taaggtagca aagactgagg ttaaggataa
    10621 ggaaacgcaa acggaagaag aaaaaccaaa gcaggacgaa agcacgcaaa cagaagctac
    10681 aaaaacggag gataaaggca cacagacaga gctttctaaa gacgatattt ctaagatgga
    10741 aaaagaggct aaagagcttc aagaaaaatt tgataagtta aatggtgagc ttaaagacaa
    10801 ggataagcag aaagaaaaaa tcaaagacct tgaagatgaa attgacagcc tgaaagagaa
    10861 aatgaagaaa gataaaggaa ataaggactt atcagaagat atgaaaaagg aaatagataa
    10921 gctgactgat aaggtgaaag agcttgagaa aaaggcaact gaaacaaaga aatcttctga
    10981 agcaataaat tctgttacac cgattagtcc tatttccgga attaagacaa gctcaagcat
    11041 ttctccccaa acaccacaga cttctgtaag tagttccggt aaaggctcat ctgatacggt
    11101 gagttcaggg aatgctacaa aggatacaag caaaacagaa gtaaaggaga aagaaaagga
    11161 agttcgctat tctaataaat tgacagcaaa agcacctgct aataacagca gtcaagattc
    11221 gtcaatggag ggggcaagta gtaatgtaaa taccaataag ggagtagctt catctccgtc
    11281 aaaggcaaga ggaactgtta cagaaaataa agataatgga aataaagatt atccgattca
    11341 tcatggggat agcagcgata ataaagaaac ggatcaatat tccgctgatg caagacagtt
    11401 tattaccttt caaactaaaa acggtaagac ctttcatctc atcatcaacc acgatgagga
    11461 tagtgagaat gtcatgcttc ttacagaagt atccgaagat gatttgctta acatggtaga
    11521 gaaaaaagaa gctccaaagc aggagattgt aaaagaagaa cctgttaagg aagaagtaaa
    11581 gcctgagaaa aaagaagaaa agagtaattt aggaacatat attattctgc ttcttgttgt
    11641 aggcggagca ttgggagcag gatactactt taaggttgta aaaaagaaag aagataagga
    11701 gcttgaagca ttagaggaag aagatgatga tttcttttct gaagctgaaa gcgaggaaga
    11761 aacaaatgat gtagatgaag tagaagcgga agatgagcag taatgctgca ccaaaaaaat
    11821 acagtatttg gtgcaaatgc agggcgggag aataaaatct ttcgcccttt tatattgaaa
    11881 acaggaggca gtacagaaat gaagttagtc attgcagaaa aaccaagtgt agcattaagt
    11941 attgcaaaag tacttggagc aaataaaaag aaagacggat attatgaggg aaatggatac
    12001 aaagtatctt ggtgtgttgg acacttaatt caaatggcaa atccggatgt ttatgatgaa
    12061 aagtatgcca agtggaatat ggttgattta ccgattatcc ccaaggacta taagtatgaa
    12121 gtggcaaagt caaccaagaa acaatttaac atccttaaaa agttgatgaa cgacaaagaa
    12181 attgatacgg ttatcaatgc gtgcgatgca ggtagagaag gggagagcat ttttagactt
    12241 gtatataatc aagtgaattg taaaaagaag atgaaacacc tttggatttc atctatggaa
    12301 gatactgcca ttaaagatgg ctttgatcat ctaaaagacg gaaaagatta cgataatctc
    12361 tttgagtcgg cacaggcaag agctatcgct gactggcttg tcggaatgaa tatcagcagg
    12421 ctctattctt gtctgtataa gcaaaattac agtgttggca gagtacaaac accgactctt
    12481 gctatgatcg taaaaagaga tgatgagata gcaaacttta agaaagaaaa atattatacg
    12541 gtagagcttt ctacaaatag ctttacactt tcaacagata gaattgatga tgaaatagca
    12601 gcagagcagc tcttaacttt agtgggcaat aagattgaaa taactgatgt cattcaaaaa
    12661 gaaaagatta ctaaatgtac tgcccccaaa aagttggacg aataattatt gaaaggattt
    12721 agttctgtat tgcacagggc taagtccttt tagctttgct ttaatgc
//
LOCUS       DARYXZ010000057        12358 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYXZ010000057 DARYXZ010000000
VERSION     DARYXZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12358
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TV186_001696"
     CDS             complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TV186_001696"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL1533063.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2577..3230)
                     /locus_tag="TV186_001697"
     CDS             complement(2577..3230)
                     /locus_tag="TV186_001697"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533064.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3270..3899)
                     /locus_tag="TV186_001698"
     CDS             complement(3270..3899)
                     /locus_tag="TV186_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1533065.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3901..4902)
                     /locus_tag="TV186_001699"
     CDS             complement(3901..4902)
                     /locus_tag="TV186_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1533066.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4935..5576)
                     /locus_tag="TV186_001700"
     CDS             complement(4935..5576)
                     /locus_tag="TV186_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL1533067.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5611..6405)
                     /locus_tag="TV186_001701"
     CDS             complement(5611..6405)
                     /locus_tag="TV186_001701"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL1533068.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6714..7148
                     /locus_tag="TV186_001702"
     CDS             6714..7148
                     /locus_tag="TV186_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1533069.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEADEADLDEGGI"
     gene            7148..8347
                     /locus_tag="TV186_001703"
     CDS             7148..8347
                     /locus_tag="TV186_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1533070.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8393..8881
                     /locus_tag="TV186_001704"
     CDS             8393..8881
                     /locus_tag="TV186_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL1533071.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8896..9675
                     /locus_tag="TV186_001705"
     CDS             8896..9675
                     /locus_tag="TV186_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1533072.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9662..10483
                     /locus_tag="TV186_001706"
     CDS             9662..10483
                     /locus_tag="TV186_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1533073.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10883..11884
                     /locus_tag="TV186_001707"
     CDS             10883..11884
                     /locus_tag="TV186_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1533074.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
BASE COUNT         3477 a         2845 c         2448 g         3588 t
ORIGIN      
        1 gctcaggggg gattttaact tattactaat gtgcttgaat ggctatgata aggccttaaa
       61 agatagctgc ttaaagtcat ttcccacctt ttgatagagg tataagcctg atttttcaag
      121 actcaattga ccattaacca cctccttagc ctgattgtat ttgaccaccg ccaacaggcc
      181 ttgtttctta tcatggatca gctgaagctt actgtcattt cgaagcacct caatacgtgc
      241 ttcgctgcac accttgtcaa agtctgcttt gctgatattt ggaagtaggg tgtaggcata
      301 gctatcacta gcctgagaat gagtttgact gattgtgata aagctttggg agatgaggtc
      361 tttattgtta ctatttgtat taatctcaga ccaacagcct gactgcacct ttcgcgatag
      421 cgctaatgcg gttggcttgg caaaaaggta accaatatta gcttgaccgt ctttagaaag
      481 tagtaaaaga ctggtcacat catctcgata caggatctcc tctgttagcg ctgtctcctg
      541 cccattgata aaaagagtgt agctgttgtc tgggttttct ttgcgttgat caatggtagt
      601 agtcactgcc tgatgtgtct gactagtgat ggcggtgcca agaaaaacaa tttggtcatc
      661 taagatcgtc caagacttct tggcactcac tgtcctatcc caattttgaa aatccataac
      721 agctaaagct gttttgtctc ccgccttgat cgctccaaca aaggacgatg gcagggtaga
      781 catgcctgct ttttctttgg ccttttcttt ataatcattg gttagctttt ttaaataggc
      841 tactgtcacg tcctctcgcc tgacctctgc ttccgttgtt ccagccatct ttaaaggatt
      901 aacagtcggc caaaagtggt ctgagtaatg acccaaatca ctgttataaa ggtaaaacat
      961 gccatctcct gtataccaac cacgtgtatt ttcatcgttc atggcttcaa aattcagagt
     1021 tttgttggaa tgcatggata aagcaaaggc aaaatccttt tccgcattgt agtaggccaa
     1081 tttatccatc tggttaaaaa gagataggta gctcttaact ggactggctt ggattgtggt
     1141 atcctccaag agctctttga atagcttcat gtcatagtag cttgataggc tctctaaaat
     1201 agtctcctga ttatggaagg ccaaaacagc cttgatctta cccttgatcc tgattttagc
     1261 ttgctctggc aatgcctcag ccagtcttag cattcctctt agtgcttcta aggctgcctg
     1321 ccttgaggag gcattttcac gactgatgga gcgcccacga ctcatatcca tgagctcccc
     1381 atgaaccatc aagggcaaga aggcttgctc aatccaatga gtcatgacct ctagcttttg
     1441 ctggtctagg ctagtagcta atagctgaag taatggtacc agctgagaca agccatcaat
     1501 aaggacattg ccataggctc cagtgtaggc gacattggta tggtcaatat aagagccatc
     1561 ttcataaaag ccctcacccc ttgatccctt tggctgaaaa gcaaataagg tatctagggc
     1621 tgctatactg tcttgaagcg ctttcttatc atgctttaac agagcttcaa taatcttcac
     1681 tcgtcccata tcaacaaggt tacccccaat ggccttaaaa ggattcacaa gggttaagcg
     1741 aaattgtcta ggattaggaa caaagtgaga aattccttta gtatagcgct tgatctcctc
     1801 ttgagtgaca taagggtaaa tgaaggctag ggtattgaca atagctcttg gggtaccaat
     1861 ttcaaaatcc caccaattag ccttgccttc aatatccttt tgcggatgat agtaattaag
     1921 tgtcagccag gctaatttat ccttgatcag tcttatcagc tccttatcct gataatacct
     1981 agaggctagg ctactcacct gcttggccat ttcctctaaa cgcctacagg tagctgtcat
     2041 atgagacgat tgatgaagat ccgccaaatc actccaaagg tatgtgcttt tctgatcctt
     2101 ggtcagatca gctagattct tggtcacgct gtcgtccagt ttttggttta atgccaccat
     2161 ggctggactt gatcggtcaa agttttctgc tcccaaaatc acctcacacc actttgtgat
     2221 caaggaggtt gtttgagggg cttctgctgc taaaatctca actggtaccg ttgctactct
     2281 ttgcccctct tgatccaaca cctctaaaag cgttttcccc tgcgccaaag gaattaaaag
     2341 accattttcc acgcgcacaa tgttgctgga ctccgctgca atctgataat gatagtcagc
     2401 catttccatg aggtagtgct tatttaaagg caggacgatt tgctcctcta agtaatgtga
     2461 agcaatcttg atgtcatcac ttggcttatc accagcctct ctcaaagaaa ggttatcaaa
     2521 gaccacctgt ccatgaccgg cctcataaaa gagctctagc ttgatttgat taacctttag
     2581 cttagggata taaagctttt cttggtgttt tttctcagtt cctgttgcca tcgaagccac
     2641 aagcgttgct cttttgcagc accagaacct tgctttattt cttcaatgat acgcgcaaaa
     2701 gcctgacctg ttttatcctt tgtctcaatg tcaaaggtca gcaaatactg cttgtctgga
     2761 ttgatggcaa cggtttggtg cacacagcct ctaaatctct gattgccatc gctagtcatt
     2821 gtcagcttgt tatcagagac agcaatttta ggacagccct gactcttact agcgtcctta
     2881 taatccttcc aatcatttgc agactccttg ctccaaaggc ttgtactttg atgctcttga
     2941 gcaggactgg tctgatcaaa ttgaggattt ttaagcaggt tatcacctgt gagaatgagc
     3001 tgctccccaa gactggattc cgtagctact gacgacgcgt cttgagtgtc tggggagctt
     3061 tcttgagaag cctcctcagt ttttagtggt gctttcttta ccctctgaag ctccttggaa
     3121 atggcttttg ctgctgtttt ttcttctgct aagactgttg gtgcccgaaa taaacaagct
     3181 agtatgatac tagagcaaac agaagatgat agtttttttc tttgcttcat ctgatacctc
     3241 cttgcttttt taatgtttta tgaccgactt taacagctac tcatgtaatc tgcagccctt
     3301 gctgtgattg cctgaaattg accctgagct gccaattgat taaattctcc tccaactccc
     3361 agcacctgag cacctgcggc aaaccagtct gacacatttg tgacagttac gccacctgtt
     3421 accatgacat caacctgcgg caaaggagat ttgattgcct taataaagga catgccaact
     3481 gtggcacctg gaaagacctt gaccatctct gcacctgatt ccaaggcagt cacgacctcc
     3541 tcaatagtca tacagcccgg aatataagca atagcatatc gatgacatag gcggcttgtc
     3601 tgcctgctaa agctaggaga cacaataaat tgagcacccg ctaaaatagc tagccttgct
     3661 gtgacatcat caagaaccgt cccagccccg atcaggatct ctggatcatt gccaactgct
     3721 tcacgcaggc ctgcaataac ctgactggca aagggattag tataggccac ctcaatggtt
     3781 ttgatcccac cttcaatacc tgctaggctg caagccattg cttctttttt agaagctccc
     3841 cgaacgacta aggctaattt attggctttt agccttaaca tgatttctga ttttctcata
     3901 ttaccttctt acctctcggt ttcccttcat caccctatca acctgactaa caggaacaaa
     3961 gagctgatca tcagcaactg tacacttaag actagctgtc gcagcagcaa aatcaagcgc
     4021 agcagcaata gcctgtcctc tcatcaattg atataagcag cctgcaacaa aggcatcacc
     4081 actgccaact cgttgcaaaa caggcgttga tagctcaatg gagcgatgta actgcccatc
     4141 ataggcatag gctaggtaat gattgattcc ttggtcatcg atgtgacgtt ccgtgtgaaa
     4201 aatggctttt aagtgatatg cctcatataa ggcagccaag cgctccttga cagcaccttg
     4261 acctgcctta gctctatcaa acatggcatg atcagcttga ttacacatta agggctccat
     4321 accaaagatc aggtctgcat actgtgcaaa atgagagaac aatgtctttg cctccctgac
     4381 tgaaatcatc gagctgcgaa aattcaaatc aaaggaaaca cagacctgcc gcttcattgc
     4441 ctcaatagcc agctgctcaa caaggtcctg actgactttt cctaaagcca aggtaatgcc
     4501 actaaaatga aaatgagtaa cttcctcaaa tagtttacca taatccagat cttttgggcc
     4561 caataaacta aagctagagg cagagcgatc ataagcgacc tgactaggac ggcagccaaa
     4621 gccattttcc aaataataaa taccaacccg atcaccacac cattgcacat gctctgtggc
     4681 aacaccgctt tgcttcaaaa aggcctcaac gcttcgtcca acctgattat caggaagggc
     4741 agtcagcagg ctactctctg ctctaaagcc actaagcgtt cttgcaatat taacctctga
     4801 gccaccataa tacagctgtg cttgacaggc atgtcctaac gtctgaaaat gactgggact
     4861 gatgcgaatc agcggctctc ccaccaataa taccttggtc ataggggtat cctttctata
     4921 gctgcagata agacttattg ctgaaggact tctcttaggt agtcgacaag gtctgatggc
     4981 tcggcattag caaagaaata atgctggaag tgctctccag aaatggtttc cttcaagaaa
     5041 tcttgatcaa tctcctttaa cacctccaac aaagaacgat aagtcacagc cttcaattcg
     5101 ctcaaaattc tagcgttacg ttgctctggg atggcccgct ctttgggata gccgcccccc
     5161 atcggctcag caaataagcg ctcaaacatc agggtcaggt taagctctgc cccccaacca
     5221 aagccctttg caaatggaat agacaaggca ttgccaccat taatctgagc aaaaaggtag
     5281 gcttctgttg gctcactagc aaagccacag gtcacacctg gaaagctatt taaggccagc
     5341 atagcaccca caccagtccc acagcccgtt acaacaaaat cagctgcctt acttgtcaat
     5401 aaaatagaag ctagtagccc gttttgcaca taggtcagct gactttcgcc ctccttgcca
     5461 tacataccat agttaaagac ctcatagcca tgcttattag taacagagac taaggtctcg
     5521 taaataatac tgtttttagc tgcttgactg ttttcattaa ttaatgcaat tttcatcttc
     5581 tgtaatctcc tttgatgctt ttttgtttct ttacggttgt ttgccaatgt aagctaaaat
     5641 gcctccatca acataaagga tatgcccatt gacaaagtta ctcgcctcac tagccaaaaa
     5701 tatagctgga ccagccagat ctgctggtgt tccccaacgc gctgccggag tcttagcaat
     5761 aataaactga tcaaaggggt gacggctgcc atcagcctga cgctctctta aaggtgctgt
     5821 ctgaggcgtt gcaatatagc caggcccaat gccattgcac tggatattgg cttctccaaa
     5881 ttctgaagcg atgtttttgg ttaacatctt aagaccaccc ttagctgccg cataagcact
     5941 aaccgtttca cgaccaagct cactcatcat cgaacagata ttgatgattt tcccatgccc
     6001 ttttttaatc attgatggca gaactgcctt tgaaacaata aatggcgcat tcaggtctat
     6061 atctaccacc tgacgaaaat ccttagccgt catctcaagc atcggtgtcc gtttaatgat
     6121 acctgcatta ttcacaagaa tatcaataat accaacctct ttttcaatct gagccaccat
     6181 ctcttgaatc cctacttcat cagtgacatc acaaacatag ccatgagctt taatgccaaa
     6241 ctctcgataa gctgctaatc cttgatccac taaatcctgc ttgatgtcat taaagacgat
     6301 ctttgctcca gccatggcat aggccttagc aatctcaaag ccaatcccat acgaggctcc
     6361 cgttatcaag gcaattttgc cctctaaaga aaagaaatgt tccattgttt tacctctcaa
     6421 tctcaatatt taagtaaacc tgtttatcaa aactatagca agactaatcc attttgtcaa
     6481 tcattttagt aaaaacacaa aaaagagcta aagtttttct tattgtcatt atcgaggaag
     6541 gcttcttagc tatatttttc ttgctcttac tcgctttact tcctataagg atcccaaaaa
     6601 ttaggccata ttgatcgctt attttgataa aataacaaaa aagtgttgac aaacattttt
     6661 gaaagcgcta taatttttct gagtaaaccg gtaaactaaa aaggagctta ttcatgattt
     6721 ctattattgt tattggtcat gggcattttg ccagtggtat tgtctcgtct ttagagttaa
     6781 ttgcaggcaa gcaagagggc ataactgcta ttgattttac tgctgagatg accgctgctg
     6841 atgtgcatga gcgcctatca gtagtcttac agtcaaagac tcaggcactt atgctttgtg
     6901 acttattagg cggcacccca tttaaggtag cagctacctt gatggaggag ctttctgaga
     6961 gcacacttga tgtcctgtct ggactcaatc tagccatgct aatagaagca gtctttgcta
     7021 ggcaagagca gcttgatcta gaacaaattg tcgctaagct attaaccaca gccaaggaag
     7081 ggatcagtaa ttggaaatcc ctctctggtg aggctgatga agcagacctt gatgaaggag
     7141 ggatttaatg actagacaga tcaaagaggt tacccttgag cctctcatac aagcagaggt
     7201 ctatagccag cagccatatc taacaaaagc tgatattgag gcagctattt tattagccct
     7261 taagcaaatc cgattaaaca tggattattt tggtactgat ttccctaggc cagccactaa
     7321 ggacaattgc tacccaatta tggataatac cgagtggacc aatggctttt ggaccggctg
     7381 cctatggctg gcctacgaat acactggtaa tgacactatc aagtcactag cacaggcaaa
     7441 tgacctgtcc ttcttagaac gcgtcaccaa agacattgag cttgaccatc atgatttagg
     7501 atttctttat tcaccctctt gcatggctga gtggaagctt ttaaaaacac ctgaagccag
     7561 acaggcagcc ttaaaggcag cagataaatt gattgagcgc tatcaggaaa aaggcggctt
     7621 tattcaagcc tggggacaac tcgggaaagc agaagattac cgcttaatta ttgattgtct
     7681 tttaaatatc cagctactct tttttgccag tcaagaaaca ggagatgaca ggtatcgtca
     7741 aatggctatc aatcactttt atgcctcagc caacaatgtg attcgtgatg acgcctctgc
     7801 ttatcatacc ttctactttg accctgaaac aggtgatcca atcaaaggag ttacacgcca
     7861 aggctacagt gatgactccg cctgggccag aggacaagct tggggaatct atggaattcc
     7921 cttgacctat cgcttcttga aggatccaca gctaattgcc ttatttaaag gaatgacgca
     7981 ctatttcctc aatcgcttgc ccaaggatca ggtatcctat tgggatttga tctttgaaga
     8041 tggcagtggt cagtctaagg acagctccgc aactgctatt gctgtttgtg gtattcacga
     8101 gatgttaaaa catttaccag agaatgatcc tgacaagaaa gcttatcaag ctgccatgca
     8161 ctgtatgctc agatcattaa ttgatagcta tgccaacaag gacatcaagc ctggtgctcc
     8221 acttttacgt catggcgttt actcttggca ctctggcaag ggcgttgatg agggaaatat
     8281 ctggggagat tactactatt tagaagccct gctgcgcttt tacaaggact ggacccctta
     8341 ttggtaggct gatagcattt agcctacaaa gactattgtt aaaggagata ttatgacacc
     8401 accaaacatt atcatgacca gagttgatga gcgtttgatt catggtcaag gccagctatg
     8461 gatcaaattt ttaaattgca acactgtcat tgtggctaat gatgccgttg ctgaagacaa
     8521 aatccaacag tctctgatga aacctgtcgt tccatcaagc attgccatgc gctttttttc
     8581 cattcaaaag gtgattgacg tgattcacaa agcaagccct gctcagacaa tctttattgt
     8641 tgttaaggat ttagaagaca tcaagcgctt ggttgaagga ggggtgccca ttaaagaggt
     8701 caatcttgga aacattcata aaacagacga taaaatcgcc attacccaat tcatttcgct
     8761 aggcgacaag gacaaggcta ttattcggac attgactcac gatcatcata ttgtctttaa
     8821 cactaaaaca actccagctg gcaatggtgc ctctgaggtt aatattttag attatattta
     8881 agaaaggaaa ttgatatgga tatcaatttg ttacaagcac ttttaatcgg tctttggaca
     8941 gccttttgtt tcagcggaat gttacttggt atctacacca atcgctgtat cattctgtct
     9001 tttggtgtcg gcattatctt gggggacttg ccaacagcac ttagcatggg agctatatct
     9061 gaattagctt atatgggatt tggtgtcggt gctggtggta ctgtgccacc caacccaatc
     9121 ggacctggta tctttggtac cttgatggct attaccagtg ctggtaaagt tactccggaa
     9181 gctgccttag ctctttcgac accaattgcc gttgctattc aatttcttca aacctttacc
     9241 tatacagctt ttgctggtgc tcctgaaaca gctaaaaaac agcttcaaaa agggaatatt
     9301 aaaggcttta catttgccgc caatggtacc atctgggctt ttgctgtgat tggcttagga
     9361 cttggtttat taggcgcctt gtcaatggat actttacttc atttggttga ttatatccca
     9421 cctgtcctcc taaatggatt aaccgttgct ggtaaaatgc ttcctgctat cggttttgct
     9481 atgattctat ctgttatggc taaaaaagag ctgattcctt ttgtcttaat tggttatgtc
     9541 tgtgcagctt acctgcaaat tccaaccatc ggtattgcca tcataggcat tatcttcgcc
     9601 ctaaatgaat actacaacaa accaaagcat gcaacaacag ctgaacaagg aggtcaacaa
     9661 gatgactgga tctaataagc tcacaaagcg tgattatctg aaaactgctc ttagagcctt
     9721 tttcctgcaa aatggcttta actatagcaa ttatcaagga ataggctatg ccaatgtcgt
     9781 ttacccagcc ctaaaaaagc attttggcaa tgacaaaaca ggcctttaca aagcactaga
     9841 gaacaattgt gcattttaca atacaaaccc tcatttccta ccttttatca ccagcctaca
     9901 cctggtcatg ctagaaaata atcggcctga agaagaaacc cgcaatatca agatggcact
     9961 catgggacct ctagcaggca tcggggatac ccttacgcaa ttttgtttag caccactctt
    10021 ttcgaccatt gctgcttcct tagcaagtga cggcctgatt ttggggccaa ttctcttttt
    10081 cctagccatg aatattattc taacagctat taaaattggc tctggactct atggctacaa
    10141 ggtggggaca agctttattg ataaattaag cgaacaaatg gcaattgtat ctcgcatggc
    10201 aaatattgtc ggagttacag tgattgctgg tctagctgct acttctgtta agatatctgt
    10261 tcccatcaca tttgcagcag gcaaggtcga cgctgcaaat gcagcccaaa aatttgtgac
    10321 cattcaggga atgctggata agattgcacc agctcttctg ccagccctct tcactctctt
    10381 gatgtattac ctcattaaaa cgaaaaaatg gacaacctat aaattagtta ttctaacagt
    10441 tattattggt attgttggca gctggttagg ggtgttagcc tagcagtctt agagattctg
    10501 ttaatcagta ttggagggtc tccattagcg atgagcaggt ctcttttcta ttgggcaaag
    10561 ctaagcattg acaccatcaa ctctcgtagc ctcagtcagg tcttttgccc tgtagagcct
    10621 ttaagcacaa gcctttactg ctagctgtga tgaaggcgtc ctccttctac tggcttctgg
    10681 cacaattaat cctttatatc tctacaagca catgatttag cggctgattg cgcgccaatc
    10741 ttacagaagg tcgcaactta agaaagagta ggatcatttt tgacctcttc aaaggtcata
    10801 ttcttggact gaaatattaa aacaattacc attccatatg ttataataaa actactaatg
    10861 atgacaaaaa ggggtctatg caatgcagcg caaagtaacc atcaatgata ttgctgactt
    10921 agctaaaact tcaaaaacaa ctgtttcttt ctacctcaac ggtcgatttg ataaaatgtc
    10981 tcaggagaca aaaagccgga tcaaggaggc tattgaagcc accaactaca agcctagcat
    11041 tgcagctcgc agtctcaatg ccaaggctac caaattgatc ggtgtggtta tcggtgacat
    11101 caccaatagc ttttccaacc agattgtcaa aggtattgaa agcaaggcgc aagaatttgg
    11161 ttatcagatt atcatcggca acagcaacta tgatccttca cgtgaggacg aattgattga
    11221 aaaaatgctt aacctaggtg tagatggttt tatcattcaa ccaacctcta actttagaaa
    11281 gtattcacgc atcatcgaag tgaaaaaaaa gcgcatggtt ttctttgaca gtcagctcta
    11341 tgagcatcgt acaaactggg tcaagaccaa caattatgac gctgtttatg acaccattca
    11401 gcaatgcatc accaaaggct atcaaagctt tatcatggtt actggcaatc ctaatttgct
    11461 gagcacacgc atcgagcgtg cctctggttt tattgatgtt ttagaggcta accagctcca
    11521 gtatcgtcaa atgatcatcg atgaaaacca aaccagctct caagaaattg ctcagtttct
    11581 acaaggcgca tttgataagg aacgtcacaa tctggtattt gtcccaaact gctgggctct
    11641 gcctaaggtt tttactgcca tgaaggcact aaaggtatca ttgcccgaaa ctggtctagt
    11701 tggctttgat aacatcgaat ggactcgctt gtcatcacca agtattacca ctattatcca
    11761 gcctgcttac gaagaagggg agcaagcaac cagcattttg attgatgata tcgaagggca
    11821 tagcaaggaa gccaagcaac aaatttttga ttgtcaggtt aattggcaag aatcaacctt
    11881 ctaacaggat tttttcgcct tctagacctt aaaaaatcag ccattctaat aacgatgaca
    11941 aagtaacacg aggcttaacg cttgtttgct agcatcagaa aaaacacata aatcagcctg
    12001 aactacccgg ttgatgaaac aataaaccat taagcaacgg tcttattcct cataccaaga
    12061 ggagcaaggc cgttttgacg tttttgacaa tggtcgttat tgtaaacgta acggtagtgt
    12121 attactgaca ggctcttcaa aaaagctgtc gtccttaggt catacgaggc cttcttttac
    12181 aagcgactgc tacttcttca ctactagtgt gatcttttag ccaatttctg agaacatcat
    12241 cagtaaaatc tcgcacctgc caataatggc aagcaagctt ttttgaccag caagttaatc
    12301 atgtatcact tgtgacttca actcttaact gtttgtcctt tcaagtctac tataagag
//
LOCUS       DARYXZ010000058        12296 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYXZ010000058 DARYXZ010000000
VERSION     DARYXZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12296
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(262..465)
                     /locus_tag="TV186_001708"
     CDS             complement(262..465)
                     /locus_tag="TV186_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL1533075.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(482..736)
                     /locus_tag="TV186_001709"
     CDS             complement(482..736)
                     /locus_tag="TV186_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1533076.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(1478..1774)
                     /locus_tag="TV186_001710"
     CDS             complement(1478..1774)
                     /locus_tag="TV186_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1533077.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(1781..2029)
                     /locus_tag="TV186_001711"
     CDS             complement(1781..2029)
                     /locus_tag="TV186_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL1533078.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            2289..4445
                     /locus_tag="TV186_001712"
     CDS             2289..4445
                     /locus_tag="TV186_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1533079.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            4456..5814
                     /locus_tag="TV186_001713"
     CDS             4456..5814
                     /locus_tag="TV186_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1533080.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            5914..6045
                     /locus_tag="TV186_001714"
     CDS             5914..6045
                     /locus_tag="TV186_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1533081.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(6167..7501)
                     /locus_tag="TV186_001715"
     CDS             complement(6167..7501)
                     /locus_tag="TV186_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1533082.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(7501..8250)
                     /locus_tag="TV186_001716"
     CDS             complement(7501..8250)
                     /locus_tag="TV186_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1533083.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            complement(8877..9080)
                     /locus_tag="TV186_001717"
     CDS             complement(8877..9080)
                     /locus_tag="TV186_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL1533084.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(9097..9354)
                     /locus_tag="TV186_001718"
     CDS             complement(9097..9354)
                     /locus_tag="TV186_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1533085.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TV186_001719"
     CDS             complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TV186_001719"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1533086.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(11039..12007)
                     /locus_tag="TV186_001720"
     CDS             complement(11039..12007)
                     /locus_tag="TV186_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1533087.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            complement(12147..>12296)
                     /locus_tag="TV186_001721"
     CDS             complement(12147..>12296)
                     /locus_tag="TV186_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1533088.1"
                     /translation="DCDYITGDTVMIVRKNGRIFDYVLPNEEIRDWEVVIEERVEEVM
                     RELDK"
BASE COUNT         4008 a         2785 c         1892 g         3611 t
ORIGIN      
        1 atatgacagg ctacaggagt atcattcttt aaatgttaac aattgctaaa atttcgatat
       61 taggtctatc aatatcataa tataaaggat aaaaagaaac attaagttgt catgagctaa
      121 aaataacaaa aaaaagctat ttatcgttga tatatcaaca atgtcattat ttttatctaa
      181 acctctcaca gatctataga taaaataaat ttgaaaggtg aaaataacta tagtaaatat
      241 atatttcaga ttcatatcat attatgatga agccttatag gctaaataac cacaaacagc
      301 tgcacttcca actcctccga taacagctcc ccaaggtcca atcctacttc ccaactttat
      361 acctccaaca gcacaggtca aaccacctac tactgctgca ccggcagggt tccctccaca
      421 aatgtcgtta agttcttctt ctttgatttg ataataatga gtcataaaaa acctctcttg
      481 attaaaatcc acctgttgct cctgttactc ctgcccacaa tgatacgcca aatttggctc
      541 caatgtaacc acatgctccc ataaatggag caccggcacc acttgcagca caaatagctg
      601 tccctaaccc ccagccacta acagcagcgg taccaccttc ccaaacatta gcttgccaat
      661 tattctttcc accttcaatg tgagcaagct tgtcagcgtc tataatatta aattgtttca
      721 ttaatgtcgt attcatcgtg aatacctcct atatttattt tttgtctgct gcaactgaca
      781 aacccagtat agcagataaa caatcgcttt cagtatttaa gtcttaaaat gtcgtcgaaa
      841 cgtcttgaat ggtaatacga aaaccgttaa caccaattca gtgaaaattc ctaataccca
      901 taacaaatat gagaaagctg tcttaattgc ttcaaaagct gagtttcctc ctttgacggc
      961 tgaaggctct atgctgtaat gacaaatagc ccaatcttaa atgactattt tatttttcca
     1021 gatagcaata catcatcaac agctgatgaa aataatacat ttgtggcctc agcttactaa
     1081 cttaagcctc tagaaataag gaaaagcaac tgatttgata gctaatagcg cagataatat
     1141 ttcttttcca agctcaataa gactcaaaaa taagttcttt gtaagaaaaa ataaatcact
     1201 aaccaaatga gataagctta ttgcccttgc aattatctca agctacttct tgtccgaaac
     1261 caccctagat agttaactac cacaaaacaa taggtatcag ctttaaactg atacccattg
     1321 ttatatcctg cgattagcca atcaactcaa tcgttactta ctttaccttc agctagccat
     1381 ctcacaaaat agcattgaca accttttcat gtcatttggc ctattgtgac tcaacaaaac
     1441 aataacgcca atacaacgat aaggtatgag cgttttatta tcgcctaata actcccaatg
     1501 atattaggcc tctacctagc tgtttatcac attctttgta agtagagatt tctttataga
     1561 atttagccat ttctacactc attgtttcaa ctcttatctg cttaacagct aattgacgca
     1621 gagattcaga tagcatcatc acttctctgt caaagttact tgactcccct actctatctt
     1681 taaatcttac cagaatgact cgctcttctg atgttaaggt tggatctaaa attaaattat
     1741 aaaccttatt tagtatctct tcttgcgtca acatacccaa ctaccctcta taccctggat
     1801 ggaaataacc acctcctaaa gaggatatcc aaccattaac aataacatct ttagttgctt
     1861 caaaattact tttagtaaca atatagcccc attcgccatt gctatatcgg caggcatacc
     1921 cattagaacc agacattaca aacttacaaa ttcctttgcc gccaccctca atgtgagcaa
     1981 gcttgtcagc gtctataata ttaaattgtt tcattaatgt catattcatc gtgaatatct
     2041 cctatattta ttttttacct gttgcaagca acaaacccag tatagcagat aaataactgc
     2101 tttcagtatt taagtcttaa aatgtcgtcg aaacgtcttg aatggtaatg tcgcaactga
     2161 ttaaaaaaga gtgttaatat cattattccc atttaagacg tttcaacgac tattcaagac
     2221 tagctcagtt tttttctgag cttttgtggc acaatagagt cgttacaaca gagaaaggaa
     2281 gccaaccaat gacactcttt tataaaagaa cctttgtatc acaaatagat gccagagatt
     2341 gtggcgtagc tgctctagcc tcaatcgcaa ggtattatgg ttcagattat tcattagctc
     2401 atttgagaga attagcaaaa accaataagg aagggacaac agccctcggt attgtcatgg
     2461 ctgctaagga aatgggattt gaaaccagac ccattcaagc ggatatgacc ctctttgaca
     2521 tggcagacgt gccctatcca ttgatcgtcc atgtcaataa agaaggaaag ctacagcact
     2581 actatgtggt ctacaaatct aaaaaagact atcttatcat tggtgatccc gatccaatgg
     2641 tcaaggtcac aaaaatgtcc aaggaacgct ttgcttcaga atggacaggt gtcaccatat
     2701 gtcttgctcc taagccaaat tataaaccac ataaagacca aaaaaatgga ctattaggct
     2761 tctttccgct tatttttaaa cagcgaaccc ttatatttta tatcgtgtta gcttctgtct
     2821 tggtaacggt cattaatatt gctggttcat actatctcca ggggatttta gacgagtata
     2881 ttccaaatca gctgaaatct accttaggga ttgtatcaat tggtctcatc attacctata
     2941 tactccagca gctaatgagc ttttctagag attatctttt aactgtcctt agccaacgtc
     3001 ttacgattga tgtgattctg tcctatatcc gccatatttt cgaattgccg atgtcctttt
     3061 ttgcaacacg tcgaacaggt gaggtaacct cgcgctttac agatgctaac tctattattg
     3121 atgcactcgc ttcaaccatt ttatccctct ttctagacct ctctatatta gctattgtcg
     3181 gaagtgttct tttggtgcaa aatagcaggc tttttctgct atctctgatt tctatcccag
     3241 tatataccat tatcatatgt gcctttataa agccgtttga acaaatgaat catgatgtga
     3301 tgcaaagcaa tgccatgcta agctctgcta ttatcgaaga tatcaacggg atcgaaacca
     3361 taaaatcact aaccagtgaa gaaaaccgtt accaaaaaat tgacagcgac tttgtggatt
     3421 accttgataa gtcttttaag cttagtaaat ataccatctt acaagccaca cttaagcaag
     3481 gagcgcagct aattctgaat atcatcattc tttggtttgg ggctcaactg gtcattaatg
     3541 gtaaaatttc aatcgggcaa ttaattacct ttaacacact tcttgcctat tttacaaccc
     3601 ctttagaaaa tatcattaat cttcaaacca agctccaagc agctaaggtt gccaataatc
     3661 gtctcaatga ggtctatctt gtagagtccg aatttaaagc ctcgcaagcc ttatacgatt
     3721 tatcgctctt acagggtgac attcagtttg aagctgtttc ctacaggtat ggctttggca
     3781 aggatacatt atcagatatt acattaacca ttaagcaggg agcaaaagta acccttgttg
     3841 gtgtcagcgg ctcaggaaaa acaaccctag ccaagatgct cgtcaatttc tttgaacctt
     3901 ataaaggacg tataaccatc aaccaaaacg atctcaagac cattgataaa aagaatcttc
     3961 gacaatacat caactacctt ccacaacaag cctatgtgtt taatggatct atcttagaaa
     4021 atctaacctt gggagccaag caaggcatca gccaggaaga cattcttaac gcctgtgaga
     4081 ttgctgacat tcgtcacgac atcgagcaaa tgccaatggg ataccaaacc gagctctctg
     4141 atggggctgg cttatctggc ggacaaaaac agagaattgc acttgctaga gcattactaa
     4201 cccaagctcc tatactagtt cttgatgaag caaccagcgg acttgacata ctgacagaaa
     4261 agaaaatcat tgaccgtctc atgaacatga cagacaaaac gattattttc gttgcccacc
     4321 ggcttagtat cgcagagcgc actgatcaga ttgttgttct taatcaaggg caaatcattg
     4381 aaacaggcag ccaccaggaa ttaatgaaac aaggtggatt ttattaccac ctatttagtg
     4441 aataaggaga caatcatgaa tcccaatatg tttaaaagtg cggaattcta ccaaagacgc
     4501 tatcatcatt tgacaacatt cttaacaatt cccttagccc tcttgttgac ttttcttatc
     4561 cttttttctt gctttgttta taaagaaata acggtaacgt cctacggaga aatcactccc
     4621 actcaagtca ttgcaacagt ccaatctatt agcaataatc ctataattgc gaaccatctc
     4681 accaataacc agccaatcaa acaaggagac tctattattc aatatgctaa agacctagaa
     4741 gagtctcaaa agcaggtact tgagaaacaa ttagctacct acgaaaagca aaaaagcagc
     4801 cttaatactc tattgttaag cttaaaacaa ggccagaacc tttttcagaa cgatgatcaa
     4861 tttggttacg tcaatacctt taatcatttc atgagccaag cccaagatat tgaccttggt
     4921 ttctcaaaaa taaaggcaga gaccagccag caggcccagc tgattcagga ctctattgtt
     4981 gctatcaatc agcaaataaa tagtctttct caacaaatat cagactatga agagcttcga
     5041 tctgcgatca ttaaccaatc cgatagtcta tcctccaata acccacatca agccaccctt
     5101 gatgcctatc tctctcaatc tcaagcaaac caagagactg ccaccaatca gcttctattt
     5161 caaatagacc aaaatctttt aaacctaaaa acctctatag atagcctcta taggcaacgt
     5221 gctaatctac atcaatctac cagctatgat aatagcctca acacaaagct agaaatactc
     5281 cgaacacagt ttttgataac agcctctcag cagttaacag atgtcaatca tcatattact
     5341 gagctcaagg cgcaattgga gcaagccact cttcaggtaa acaatctggt gatcaaagcc
     5401 tcaaaaagtg gcattgttca gctcaatagt gcttttgaag gcaaaattag tatcccaatc
     5461 ggtcacgata ttgcctacat ttatcctagc ctcaaacaaa caaaacaagc cttgctcact
     5521 tactatgtca gctctgaatc tgtttctctc cttaagaaga accaggttgt caggctagct
     5581 ctagatagac atggaaatca accgatagtc attacgggaa ccattaaaac cattgatgag
     5641 ctagcgacca aaaccaagca gggaaatctt tttaaggtta cagccaaact aacactttct
     5701 gaaaaagaaa gcactactat tcaatatggt cagcagggac gagtgataag tgttattgcc
     5761 aaaaaaacat tctttgactt ttataaggac aagctcttta aagtgacaga ataaccattt
     5821 agcgcttttc aacgaccatt taggacatag agtacaacaa agagtcaaga taagctataa
     5881 taacatagac agtatttaaa aggagctttc aatatggata aaccaactag acaaccaaag
     5941 tttcaggaac taacgccttc tcagttaact cagattactg gaggaggctg gcttgaaggt
     6001 cttcaaaaag ttttcaatgt ctctaagcca aaactactaa aatagtaaca ttctccattt
     6061 tcaaaacacc actacctaaa ggtactgaga cactatcgga atgatgtgat cctaaacatc
     6121 aaatctgata ggtgcaagac agttttcctt tactagtggt gtttttttat aacctaagct
     6181 caagtgtttg accaaataca tgattttgac ttatagtctt aatcatcaca ttgggataac
     6241 gattgataat ttccatagca ttataaagtc ccacacctct attatccccc ttggtgctta
     6301 ctccgaaatc atatagaaag gatagatcaa tcttctcttc cttagttgta ttttcaatca
     6361 taaatagttg cttattgtcc aaagtaaaat aagaaatcgt tatcttagac gaagaagctt
     6421 caacagcagc ctctatagca ttatcacata aaatagacac aatagtaaga aaatcaatca
     6481 gctccatgcc ttgcggactg atatcctctg gaacctctaa agatactgaa atcccacttt
     6541 ctaaagcctg actaaatttt gcagctaaaa gacttttcaa ggctgtgtca gtgacatgga
     6601 taagacgccc aacatcatat ttttgcttgc gaaatcgttt atttgaatcc ttaaagaccg
     6661 attgataaac tgacctaaca atagacatgc tatcattatc tataccaaac tttaacgtgg
     6721 caatcagatt gctatagtca tgacgaaatc ctcgaacctc tctgtaaagc tcctctatct
     6781 gacgactata gctctcaata tttgccagct gcagctctct ttgaaaggtc agtctttctt
     6841 gcagtgtatc tcttagcgac cggtccagtc tcgacacagt tcccataaat ataatccaat
     6901 agccaagcat catgcattga cgataggcat aagtatcaac agctagctca tactctaaat
     6961 aagcaagcaa ttggatcaaa aaataatagc taaccataga ccagttggtc acacctaaaa
     7021 ttcttttatc cctatcagat aaaagattaa ttcttaatgc tctgaaatca tatcgtagcc
     7081 accgcaaaaa gagaaaaacc atcaaagtag atactatatc tgtaaaaatt ccccaaaatc
     7141 catcatttgt taaatgataa tcaagtttaa aaagaggtaa gataaaaaaa ccaagcagtc
     7201 ggtaccaaag gctccacagg gtaataggaa atagcccata aaatatcaat aatgtttttg
     7261 ataagggtcg cagcaatagc catgatatca ctaccatata aattggaaga ctccaataat
     7321 tgagaagtga aatgtcggca acatgattag ctatagtgaa aaaaacagca aatcctattc
     7381 ttaaaaaagt actgaaagca acttcaagcc aggttaattg acgtccactg attttggaaa
     7441 agagcactaa cgataagcct atacttgtcg tcatttctaa gaaaaataaa ataagcttca
     7501 ttaattatct cctctatgta ggttctcaat tgttgttaaa acactgttca ttttactacg
     7561 agcaattaag cagctagagc catttcgaaa ataaaccact cgctcaatct tatctaccct
     7621 aacgacattc ctatgattaa tcaaaaaaga acgatgacat tgcaaaaaac gagactcttg
     7681 cttcaaaata tccgtcaaag tccccgtaaa ttgcattctc tccttttttg tatacaaatt
     7741 gacacgatgc gctcgtgacg atgtctcaat atacaggata tcattaaaag gcacctgtac
     7801 ctgagcataa cgagatgtaa aataaaaagc actttccgct atcgtttcac tattttgccg
     7861 cacagcatat aataaagcag tctctacccg ttgaacaaac tcagtttgag gcagctcttt
     7921 atcgatatag tccaaagcag atacctgata ctgaaaagcc aagggcataa attccgagtg
     7981 agtcgttaca aaaacaatca tcgcatctgg atttatctga cgaatttgcc tagcaacctc
     8041 aagccctttt ttgttctcat tttttatctc aatatctaaa aagaatagct gctgaccaca
     8101 gttcttcttg atagcactta atagctgatg aggccttcca aaacagtcaa gtccttgaaa
     8161 taatagctgg tgcttaacct caagctcttt aatgagcttt tctaaatatc tctgctgaat
     8221 catatcatct tctaaaataa ctactctcac ctaaactcag tcccctatcc aatctgcaga
     8281 agcattagca ctactaccgt ttcaacaaaa taataagcac aataacaaaa ataaatccat
     8341 taaaaacaac tgcatcaaaa ctcataaaaa taatattttg tacttatttt agcataaaat
     8401 accatttttg aatacactaa tctctaataa actaatgcta tctagtctta gctagcaata
     8461 acctagtgct tctaacaaca ataatcagct caacaatttt tagcagctac ctttttaaaa
     8521 aaactgggat aaaaagattt ctcaggtaag aaaaatagag attcaccaaa cagtgaatct
     8581 ctattttttg aactgaaact ccttttgtcc caaactcata agatgtattg actttatgag
     8641 atgaacaatt tgttacactt gatttgatca tcggggttta gaaaaaatag tgaaaagaat
     8701 cctcataatt cgtgaaaaat ataatttctc acccaaaaat ccaattcaag attgtattta
     8761 taagaagtag catgattaaa gttatagaaa ttcttatcaa cgcttcttct tttttaacaa
     8821 caccaaatat caatagtata atcggaacta aaactaatac tactaataat attgttttat
     8881 aatccattga taatggcctg tcctgcacca acaatgcatc ctattcctgc acccaataca
     8941 tacaatggac cagagaaagc acctgtaacg attgctccac ctgcacaatg ccctgcaaca
     9001 gagccccaat taattttacc gccatttaca cttgccaaat caagctcata taacatctga
     9061 aaatcttcgt actgcttcat ggtatatact cctttcttag ttaaatctat tacctatcat
     9121 tccacccatg catgcaaaac ctcccccaat tgcaccaaca tgtgcaccaa caaatgcacc
     9181 tggaagtacg ccaatccctc ctgctggggc accccacaaa gccccacttc cagctcctat
     9241 taacatatat cctcccatgt ctttaagaca gtccttacca gaatatccac cttcaacagt
     9301 tgcaagagcc tctatattca taacatcaaa ttgattaatc gtttctgtat tcattttgaa
     9361 tacctccata acatattttt tctttatgtc gcgatcacga tttaagtata gcattctagt
     9421 atcatatttt ttctaaaagt cttaaacggt cgttttttca tcgtaaacgg tcattttcaa
     9481 tcgttttcaa ccgttcaaga caaaattaac taccattcag gattttcatt ggataaatag
     9541 ctattttttg gctctttgcc aacccactaa agctattaat aaaaaaataa gacagtagtc
     9601 acatttaggc tactgtctct tttatctaaa gccttgatcg gtaagaaaag agccagtctt
     9661 ttccaactaa tcgattattg ttgtggtttt tgtcgctttt gtagcttcac tacagcctcg
     9721 gtccttgctg tgtgtggaaa catgtcaaca gattgaatat atatcacatc atagacctga
     9781 accaagggta ccagatcacg agccaaggtt gaggtattac aggagacata aaccatttta
     9841 gctggctgat agtgtaaaat cgtttgtaat agcttgtcat ctagtcctgt tcgaggtgga
     9901 tctacaatca aggcatcagc tcggtagcct tcagcgtacc agcttgggat cagttcctct
     9961 gccttgccag tctcataata agcattgtca aagcccaatg cctgcgcatt tttcctagca
    10021 tcagcaattg cctctggaat aatatccata ccacgaacag atcttacttt gtttgcaact
    10081 gccagaccaa ttgagccaac accgcaataa gcatcaataa tatgctcctc agctgtgggc
    10141 tcaagcgcct gaaccacttg actatataaa acctctgtct gtgtgggatt aagctgataa
    10201 aaggctcttg gcgacagggc aaagctatgg ctcaaaacct cctcttgaat ggtctcctga
    10261 ccccagagaa tctcagtttt ggcgccataa atatcactcg tttttgaagt attgatgttt
    10321 aaagcaacag tcctgatttg tggaaatgca gcagtcagct cagcaataag acctgccagc
    10381 ctcacctctt tactgcttac aaaaatcaac tgaacctgat cactggcctg tgccctacga
    10441 accataactg tacgaattcc agctactctg cgttcattat agataggaat cctataccga
    10501 tcaagcagct gagtcacatg attaacaatc gcctgtgtta gctgatcctg aaccagacaa
    10561 tcatcaatgg caaccaagca atggctccct tctgaaaata agcctgcctt gacggagcca
    10621 ccaaacgaac gcgtctgaaa ctgtaatttt gctcggtaat gctgcggctc tgccattcct
    10681 aaggtatgac gaatctcaaa ctcttcatac cccttaggct taaacttttt taaggcctgc
    10741 cgaatgatgt catccttaaa gtagagctgc ttaggatagg ccagatgcat gatttgacag
    10801 cctccacagg tctcataaat ggaacaggcc ggcttcaccc ggtttttaga agccttatta
    10861 atcaccaaga gccttgcctc agcaaaattg cgcttaacag cagtcacttg acaaaaaacc
    10921 tcttctccct tcaaggctcc gggaacaaag accaaggtct ttttataaaa accaattccc
    10981 tcaccattaa tccccattcg cttaatctta agcggtattt tttgctttat tttgacattc
    11041 attcctgact aaatattact cctaatcgct taagccttgc tatcatctgc ttgccaacac
    11101 ctggaatatc aagaagctct tgagttgtcc aggccgaaaa atcctccaga gtatgaatcc
    11161 catactgatt aaacaaattg accttactta aaggaagatc aagctcctct agaaatgtta
    11221 gctcgccttc agccccttca aaaaattcct gaacataatg ctgcaggtaa tattgtgcag
    11281 tcatcaatag cggtaggata ttaaaaaagg caaggtaaat acttgataag ctgtttggct
    11341 cgtagctctc cagggcacca gcagctaaaa tatcatctat cggaaaggct ttctgtctga
    11401 caattgccac aaagtctggc accgtctcag caaggttagc caaaatatca tcagctagct
    11461 cttctctttc agctaatagc gctccaacca tcaaaggaac ctccatcaac agatctcctc
    11521 tatgataatc cttactgtca taaaaagcct ctgccatcgt aaaatcagac tttaacacat
    11581 aaagagctaa gatttcatac cttgtcccta agtgatcccc ttcatcgtat tgatgaattt
    11641 ctaagaggtg atgtaaagct ttttcataaa gaccattttg cttatacagc atcgccagct
    11701 caaatttttg agacaagtaa ggtctctctt caagattcac ccatcccata ggcttagaag
    11761 caagccaggc ctgatgctga cagtcttcat caaaggccaa atacttgatt aagtcatagg
    11821 ctctatctcc tgcaaagtgc tccaagtccg acaacaactg gttatccatg ctgtttaaaa
    11881 gagcctctaa gtcatcactg aaaaactctg tctcatgtcc aaagagcata tcatcttctg
    11941 catcagcttg gcgatagtgc tgtaagctaa caaccttatc tctatctttt ttatcttttt
    12001 ctgtcataat gccctttcaa tctattgacc atttatactc ttattttacc atttttgtta
    12061 taatgagggt atagataaaa ctcctaaaat tgtggcttta caatgtcgtt ccccgacaat
    12121 tccccgactt ctggacgagg tcttttttat ttgtctaatt ctctcatcac ctcttccact
    12181 ctttcctcta tcacaacctc ccaatctctt atctcctcat tcggcaacac ataatcaaaa
    12241 atccgtccgt ttttgcgcac aatcataact gtgtctcctg tgatatagtc acagtc
//
LOCUS       DARYXZ010000059        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYXZ010000059 DARYXZ010000000
VERSION     DARYXZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(152..433)
                     /locus_tag="TV186_001722"
     CDS             complement(152..433)
                     /locus_tag="TV186_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL1533089.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TV186_001723"
     CDS             complement(466..1233)
                     /locus_tag="TV186_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL1533090.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TV186_001724"
     CDS             1352..2092
                     /locus_tag="TV186_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL1533091.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TV186_001725"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TV186_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TV186_001726"
     CDS             3072..5315
                     /locus_tag="TV186_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL1533092.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TV186_001727"
     CDS             5428..6489
                     /locus_tag="TV186_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL1533093.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TV186_001728"
     CDS             6567..7172
                     /locus_tag="TV186_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL1533094.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TV186_001729"
     CDS             complement(7423..8637)
                     /locus_tag="TV186_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1533095.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TV186_001730"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TV186_001730"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL1533096.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TV186_001731"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TV186_001731"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL1533097.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     GNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TV186_001732"
     CDS             10819..11535
                     /locus_tag="TV186_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1533098.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TV186_001733"
     CDS             11627..>12157
                     /locus_tag="TV186_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1533099.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3303 a         2348 c         2832 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacggta atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYXZ010000060        11377 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYXZ010000060 DARYXZ010000000
VERSION     DARYXZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11377
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..471)
                     /locus_tag="TV186_001734"
     CDS             complement(<1..471)
                     /locus_tag="TV186_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1533100.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSEVKDFNLRSKENELQEVKNLDS"
     gene            complement(558..839)
                     /locus_tag="TV186_001735"
     CDS             complement(558..839)
                     /locus_tag="TV186_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533101.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            complement(859..2490)
                     /gene="rlmD"
                     /locus_tag="TV186_001736"
     CDS             complement(859..2490)
                     /gene="rlmD"
                     /locus_tag="TV186_001736"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1533102.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            complement(2568..3998)
                     /locus_tag="TV186_001737"
     CDS             complement(2568..3998)
                     /locus_tag="TV186_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1533103.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(4197..4691)
                     /locus_tag="TV186_001738"
     CDS             complement(4197..4691)
                     /locus_tag="TV186_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1533104.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(4684..5967)
                     /gene="aroA"
                     /locus_tag="TV186_001739"
     CDS             complement(4684..5967)
                     /gene="aroA"
                     /locus_tag="TV186_001739"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL1533105.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(6100..7038)
                     /locus_tag="TV186_001740"
     CDS             complement(6100..7038)
                     /locus_tag="TV186_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL1533106.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(7040..7900)
                     /locus_tag="TV186_001741"
     CDS             complement(7040..7900)
                     /locus_tag="TV186_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL1533107.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(7917..9200)
                     /locus_tag="TV186_001742"
     CDS             complement(7917..9200)
                     /locus_tag="TV186_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1533108.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(9193..9747)
                     /locus_tag="TV186_001743"
     CDS             complement(9193..9747)
                     /locus_tag="TV186_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1533109.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(10041..11330)
                     /locus_tag="TV186_001744"
     CDS             complement(10041..11330)
                     /locus_tag="TV186_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1533110.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         3230 a         2702 c         2051 g         3394 t
ORIGIN      
        1 agagtcaagg ttcttaacct cttgaagttc attttcttta cttctgaggt taaaatcttt
       61 tacttctgaa gtaaaatttt ttaacttctg taagtcatct tcttttacct gaaatatgct
      121 cataaaatct ttgacataaa tgatattcgg ctttccaagt ccaagccgta cccgttcaat
      181 cagtccaatt ccttttttac tatctaattc atctaatgtt tttatggcag tcggctttga
      241 gatatttctt cttttcataa tttcttcgac tgtgaaatag ataaataccc tgccttcctt
      301 atcaatccag ttattcttaa aggacattcc tgtccgttta agaagcattg aataaaggat
      361 aattgcttca gcggataatc ctttaaattc ttctccatca accaatatct ccggtacttt
      421 taagaaatta aatctttccg cttctctgtt ataaaaatag tcaaagtcca tcgcttcacc
      481 tccctcctta aaaatttgca aagaaaaaga cgatagtttt tctctatcgc ctttggtaac
      541 catttttatg aaatttttta gattgatttt attgcttcat tgattccttt aaagaatgct
      601 ataactgctg ctccaaccat cggtattcca taaggactta acaaaaatcc taatactaat
      661 gcctcaatgc caagtgatat atctttttgc ataaatgatc ctattgcagc aactatacac
      721 atcagcatta agaaatacag aatagttgtt cctatgccaa gtataaatgt cagaaaggca
      781 gtaaggacac taagtagcaa gctgaatgga aacaatatta tttttattat ccacctcata
      841 taatacctct cctttctctt aaatcatttt aaagtgcctt aacgcatcca taatagcttt
      901 ttctttctca ggtgtacact gcggaataac ttgcttatct ttttttgatt tattgtaatt
      961 ctctctaagt tctattccac attttctttt tatctgtgct atatatagtg ttgaaacttt
     1021 aaaaccaaat ttttctaata tatactcttt aattttagca taggtagcct tgctttctgc
     1081 acttgtcaaa tcaagttcat caagctctat ttcaacactt atatacttat cgacattaag
     1141 tttggacaat aatgctaccg tctcgacatg atgtgtcatt ggaaacaagt ctactggctg
     1201 gactttctgg agtttatagc cgagttcctc gtagcgcttg atgtcacgcg ccatggtggc
     1261 ggggttgcag gatatatagg ttattttgtc aggctgcatc gctgcactgg ccttgataaa
     1321 gctctcagtt agtccctttc gtggggggtc tacaatgata actgttggct ttatgccctc
     1381 ctgacaccag tttgccatcg cattttcagc gctgtcagcg acatagtagg cattggtaat
     1441 accgtttagc gctgcatttt tctcggcatc acgcactgct gcttcgatca cttcgacacc
     1501 gtatactgct ttgacttctt tagcaaagga tagcccgatg gttccaatgc ctgaataggc
     1561 atcaatcacc acatcgtcag cggtcaattc agaaaaatca atagctgttt gatagagctt
     1621 ttcagccatt gttgtattga cctgatagaa ggactgagca gaaatacagt attgattgcc
     1681 caagatcgta tctgtgattg tctcttttcc ataaagcctt gtaaacgcct taccaaagat
     1741 aacattagta ggcttgtcat tgatattttg caggatagaa gtaatcgctg gaaattctgc
     1801 gacaaggcta tcaatcatct ggttgatacg aaagatttta ggtcgtgttg tcactaaaac
     1861 cagcatgatt tctcctgaat aatgcccacg acgaaccaca agatgacgaa tcaggcctga
     1921 ctgctccttt tcgtcatagg gcttgatgtc aaaacggcgc aaaaggtcgc gtgtaaaggc
     1981 aatcaagcga tcaatttcct tatcttgaat gtaaaaatca gaaatcggca ctagctcatg
     2041 agaatgctta cggaaaaaac cagtctctag ctgaccattg acacgacgaa caggaacctg
     2101 ggctttattt cgataagcat aaggatattc cataccaatt gtttctttga cctcaacatt
     2161 gctaatccct gcaatcttat agagactatc ctgaacctgc ttttgcttaa agagcagctg
     2221 ctgcggataa agcaagtgcc ccaaatcagc aatacctgta cgcagatagg tcacatccag
     2281 ctttttttga cgcatcggtg aggttgttag ataggtctct accttgccaa agccactgtt
     2341 tttattgacc tttaggacac gcatctgaat gatctcacct ggaagagcat tttcaacaaa
     2401 gaaaacaaag ccttcatgct tagcgattcc taagccatca tggcttaaat cagaaatttc
     2461 cacctgaaca atatcgtttt tacttaacat ttactttcct tttcttttac tacactaatc
     2521 actcaaaaaa gaagagcaac catcgttacc cttcattata gcatatctta gcgtaatccc
     2581 agcttagata atcgattttg atacttagca aaatcaataa agagagcctg accaccatac
     2641 atgtcatatt catcaatcca atccccattt tcaggaatcg tcacatgctc cacaccgttt
     2701 ttgccattag tcaagacgga cactccattt ttaaggacaa atgggaagga gacattggtt
     2761 gaggttaggg cataaatctt accaatagct gctgagcccg taaagagctt ggttggatcc
     2821 ttgatttgag acatgatagc agccatcacc tgctgctgac gtacggtccg accaaaatca
     2881 ccctcatcgt cctttcggaa gcgagcatag ttgagcaggg tacgaccatc cattttttgc
     2941 tcaccaaccg ttatggtttg gttgggaacc actccgtctt tcattcgtaa atcatctggt
     3001 acatcaacag cagcgactgc ttcgccattt acagtagcaa atttggcatc aatggtaaca
     3061 ccatctggaa acagtgtgtc aatagcctca gcaaaggttt caaagtcaac catgacataa
     3121 tatttaatgt caatatcaaa attatgcttg agtgtctgac gcacaaattc tgctccttga
     3181 tgattttcct gctctcctaa attaaaggag gcgttcaatt ttaaatcata ggaatcctga
     3241 ttattatagc tatagccagg aatattaacc aaggtatccc tcatgaagga gaccattttg
     3301 attttattct ccttattgcc aacattaacc accatgattg tatctgttcg agcatctgtt
     3361 gagccttgcg taatcctctg gtctgagcct agaattaaaa tattagtgcc atcgctagta
     3421 tcctgaccat gaaagacctg cgaaactgct ggcttataat tggccttgtt agtagacacg
     3481 tccatcattc ccttgaaaaa catgaaagct atccctgcaa caagcagcag caacaagaaa
     3541 aagagtattc tgaaaaaacg tctcagacgt cccttctttt ttttccttct acccttttta
     3601 ggcatagcct caggcgcaag ctcctcatag atcgcctgat ctgggtcatc atagaagtcc
     3661 tgctgagggg ctagtattgg cttttgctga tgccttttgc tacgtctttc tgatcttgga
     3721 taaagaggca ggccattagg cccagcctgc tgctcatcac tcatatcata agcatcagca
     3781 ttatcctgtg aagcttgagc ataatcgtca cgcccacccc tagtataatg agtcaaggag
     3841 cgctgagaac gagaaggcat agcccttgac tccatctttg actttaaaaa ggtaaattct
     3901 ctgcgttcag tctcagtcaa ataatttaaa tttcttaata aataaaaata tcgtaattct
     3961 tcgtggtggc ttagaccacc cttttggtat ctcgtcatgc tcttccaact cttagtattc
     4021 taatacaatt tcttctattc tttgtctaat gattctatta taacctatat taacgagatt
     4081 gtcctctaaa atcgttagaa ttcaacttta tttcaaccta tatattagct tttcatacct
     4141 aatcattaag aaaagctggg ctgcgaatag gaggccaaaa gtctaatcct cagcagttac
     4201 gacatattgg caatgattgc tgcaacctcc tttggtgttc tatgctcaac attaatcact
     4261 ttgtctgcca atccctcata caaggccatg cgctgctgaa aaatagcata gagttctgct
     4321 tcagaatgat ttaaaaacag tggtctttgg catagcctat cttttttaag ccgatcatac
     4381 aaagcctcaa aggaggctgt taagaggata ttatttttgt gattttttct gattaattct
     4441 cggtttgcct tactaaggac aacacctcca ccagttgata cgatagtctc attatcaagt
     4501 gccagcactt cctgtaaggt atctgactca agctttctaa aggctgcttc accacgatag
     4561 gaaaaaaatg ctgatatgct catgcctatt ttagcctcaa taagcctatc catatccaaa
     4621 aaatgctcat ctaattgggc tgcaactgtc gtcttgccaa ctcccataaa tcctaatagc
     4681 agcttagtca tgccataacc tctctaaatc cttaaaaaag tcaggataag aagtcaggat
     4741 agcttctgct cgctctaggg tgacctgtcc ttcttcaacc agtagggctg caatagctgt
     4801 catcatgcca attctatgat ctccacaggt actgacagct gcaccatgta atggtgtttt
     4861 gcctctagtc accataccgt cctctgtcgc ctgaatatca gcacccatct gtcctaatac
     4921 atcagtaaca gcctgaatgc ggtcagtttc cttgacccgt aattcttgag cgtccctgat
     4981 ataagtcgtt ccctgtgcct gagttgccag caaagcaata acaggcaatt cgtcaatcaa
     5041 gcgaggaatc aagtcaccag aaatctcaat gccctttagg gtggaataag acacttttag
     5101 ggtagcagcc tgcctgtcct tatcaacagc ctgataggag atacgaccac ccattttttc
     5161 aatgacctct aaaagacctg tccgcgtagg attaatccct acattttcga gcacaagatc
     5221 tgaccccgga acaatcagac cagcagctaa ccaaaaggct gcgctagaga gatcgccagg
     5281 aatctgtaag gtctgtccct gcaaacgctg cggtcctttg atactgattt gctttccagc
     5341 tactgagagc tttcctccaa attgttcaat catctcttcg gtatgatttc ttgtcaattc
     5401 cttttcaagg ataacagtct ctccctgtgt ctgcaaagca gctaataaaa tagcagactt
     5461 gacctgagca gacgctacag gcagctgata atggatcggc cgcaactcct gacagccctt
     5521 tacaattagt ggtggaagct ctttttctcc ttgaccagat agctctgctc ccattagaga
     5581 caatggtatg gtaatacgat ccataggacg ccttgatagg ctatcatctc caagcagctg
     5641 caccgaaaaa tcctgtgctg ctaatagccc tgcaagcagg cgcatagaag tacctgaatt
     5701 gcccatgtct agaggctttt gagctggctt taggccttta aaacctcttc cttcaatgat
     5761 taaactatca gctgactcgt aaatggtgac acctaggtct cgaaaggctt gaatggtggc
     5821 taaaacatct tgccccctta aaagaccatg aatcaccgtt tgcccctctg ctatagcacc
     5881 aaaaatgact gcacgatggc taattgactt gtcacctggt acccttagac gtcccctaag
     5941 cgccttagct tttgttttta atttcatcat tactcctatt tttagtacac cagcattagc
     6001 tcagcaaagc aaataaaaga aaatgaagta aggacaaggg cccttacccc atcaactaat
     6061 caccaagcac cgtcttgttt ttcattctaa gacaagccgc tatttcttgg gcggcgcacc
     6121 atcattgcct aatgtctttt tgatgagaga aacaacattg ccgctgcgcc cctctaattt
     6181 gccgatggat agctcttgat aggtagcgtt aaaaaccgcc cccataatca atatccttgc
     6241 caggaaaata aaccatagca tgatgataaa aatcatcacc gaaccaaagg ttttaatatc
     6301 gaccattcgc tccacattat gcaccacata attaccaacc atattgctca aaaaaatcat
     6361 gacaaaggtg gtaaaaaatg ttcctggtaa gatatacctg attttcttga ttttgatatt
     6421 tggcaacaaa aaataaagca acatcagacc aacaaatata atcagtatcg taatcggctg
     6481 aatcaggaac aaaaagagcg tcgtgatgtt atcatttaag tgataatgcc tatccagcac
     6541 ctgaatcgct gccttagaaa aggttgaaaa aatcaaggca aaggtcaaca aaaacaggat
     6601 cagcaggctc gtcagcaagc ctaccaaatg accgagcaaa aagtcacgat gctcagaagc
     6661 atcataagcc ttattaaagg ccttttgcag agaggttagg cttcgcgaca ttgtccaaag
     6721 ccccgtcaag gtcgctactc ccagcacact gcctgatggc ttagaaaaaa tattaaccac
     6781 aatggaggag gcagagcgat aaatatcctt aggcagctgc tccttcatta agcgtaataa
     6841 atctgaaata tcaatattta aataaggaaa aatattagcc gcaatgacaa tgagtggaaa
     6901 ggctgtcaaa ataaggtaat aagcaactgc aatcgctgac aaatccatct ctgcactctg
     6961 aaaatggcgc ataaaggctt ggattggctc atattgccat tttgatatga ccttgtccaa
     7021 gaatttcttt attgacattc taataagttc tttcttcgcc ctgactagtt aaaatcactg
     7081 gaccatcctt tgtaatcaca aattgatgct catactggca ggacaagcca ccatcaagtg
     7141 ttttatgggc ccagcctgtt ttcatatctg tattaatttc ccatgtgcca gtattgatca
     7201 tcggctctac ggtgagcacc atgccctcct tcagacgtag tcctcttcct gctgtaccat
     7261 agttaggcac catcggctct tcgtgcatgg ttggtccaac accatgacca acaaggtctc
     7321 gaaccacacc gtagccatga ctttcagcat attgctggac tgctgcacca atgtcaccaa
     7381 tgcggttccc cacaactgcc tgctcgatcc cacgatacat ggcttccttg gtcacgtcca
     7441 tcagcctttt gacctcatca gacggtgtac ctacagcata agcccagcag gaatcagcca
     7501 aaccacctgt ataagattct gtccacttct tcatttctgc cacattatca aaatccaagg
     7561 ccgctacatc aacgacagcc ttatcaagtg gctcacttag caccatatct accttaagca
     7621 aatccccttc ctgtagaata taatggcgcg gaaaagcatg tgcaacctca tcatttagcc
     7681 cgcagcaggt agcgtaagga taatccatta attggccatc aacaccgatc tgtaaaggaa
     7741 gcacattgtc ctccttgcag cgcctgcgca catattcttc gacctcccac atgtcaaccc
     7801 caggcttaat gatctgtctg aggccaatgt gaatcccagc aagaaagtct cctgctctat
     7861 ccatagcttc tatttcacgc gcagatttta atgttatcat tgtttttgtt tctcctctaa
     7921 ttaagcttag ttgtaataat ggctttagca atcacctgat catcaaccat gacctccata
     7981 tcaagtgtac tgcttcttct attttcagtt ataattttag ggtatatcct caattgatca
     8041 tcaatttgga cagcatgtag aaagtatatc atcatttgct cgataatgat atttttttgg
     8101 tgttttttcg ttagcactct gacactgatt tcctttaaga attcagcaac cactccattt
     8161 gacagattgc cagcactatc aatcatggta ggctcaatca tgacctgata ataatccaag
     8221 gtctcctcaa ggcttgatag catttgctgg ctataggtgt aaagatttcc cggctggtga
     8281 ttcggcaggt tttccatagc ctgtcgtctg gtaataatcc ccagcagaaa atgatgatca
     8341 tcaactactg ggagcatgtt caaatcctca aagatcattt tttgactaat attagccagg
     8401 ctagcattgg gctttgcagt gataggattt ggagacatca cctgctcaag tctagtctca
     8461 gcaggctgat ccaccacatc acgcatactg accacaccaa ccacctgatc aagcgcatct
     8521 acaattggaa accttacttg acctgtcttt ttaatcagtg cattaaattc ctcgacagtg
     8581 tctgtctcat aaaggcagcc gtattcttca actggaatca gaacctgagc aactgttttt
     8641 aaatcagtct taatgcgaat attagacaag gcatggttaa tcatcgttgc cactgtaaag
     8701 gtatcgtaat gtgtcaccat aaccggaata ccttggctat cagctgtttc aataacctgc
     8761 ttagacaccg gaaagccacc cgtcactaag atagcattgt gatttttaag ggctaacagt
     8821 tggatatttt cacgatcgcc aacaatcaaa agccctcctt tgatcaaata acggtgaata
     8881 ttttgctggg tcatcgctcc aatagaaaac ttgctaaact catgtcccaa accagcatga
     8941 ccggctaaaa cctcagaatc actgatcctt gcaatttcgg cataggtcaa acggtcaata
     9001 cgaacccgtc cttttttctc aatgcggaca gtaccactac gcggcttggt ctcaacaatc
     9061 ccccgatttt cagcctcctt gatcgctcta taggcagtac catcactaac ctttaaatga
     9121 tttgaaatac ttcggacgct cacacgcttt ccaatagcaa gtctttctaa ataatctaaa
     9181 atgtcttgat gcttactcat aatgatactc acctatcgtt agttgatatt ctaaataatc
     9241 tcgtatgtga tgactatgcc gatcactgcc cttaaattgc tttgttaatc gaaagccggc
     9301 tttttcagca accctctggc tggccttgtt ttccagatgt gtcacaatga tcagctgcct
     9361 caagccaaac tcctgaaaag ctaaaaaggt aagcgtcttt aagacctcgg tcattaagcc
     9421 ctgtccccaa aagggctgcg ctaaaaaata gccaatctca gcacttgcct gctgcttatc
     9481 atatttttct agtctaatag agccaagcat gctatggctg gtcttatcct ctattaacca
     9541 gactcccaag ggctctttca taaaagcatt gaccattaag aaatcactct cagccttggt
     9601 catgctctct ggaaacacaa actggtaatg gctgttatga ctgatcatat cataaaacgg
     9661 ctgatgatct gcatattgaa agggcctcaa gagcagtcgt tgcgtctcaa caaaagcaaa
     9721 ccttgctagc tgtgtccaaa tatccatagc ctccccttca acatgcctgt aatactatta
     9781 ttatagcaga tatcacctaa acattctata actgtcatga gttttgccat gatgatcata
     9841 ataacctgac aagccatatc atagctcaat cagactctaa gctgttaaac tattactaac
     9901 agtcaaaacc aaaaaagaga agaccgtctg atcttctctt gctatcttat ctgctaatgc
     9961 ttaaatgggc tacatcatag aaaagtccta tgagtaagct catccttcta aggctaaaca
    10021 tgcttccata aatacactgc ttagtcctgc tgacgctttg aagtcactgc taaagcacct
    10081 gcactcgcca taatggcaag agccgctgct gtaaagaatg gattagcctt ctcaccagtc
    10141 gttggaagag tcttagcctt ttgcttatct ttttgcttag ctggtgctgt cttagttgct
    10201 ggtgtaagcg gtgtcaacgg aagagaagct gatggctttt ctggatcagc tggactctcc
    10261 tctaaagcct cagtgactgt aaatgtcttt gtagcagcgt cataagccca ttcaccagta
    10321 acgccattgt cattggcata ttgcctgaag gtctgctcgg ctgtggctgc gtctactgcc
    10381 ttggtagctg tttcacctga gaaggtaacc cccttaataa caagcctata ggtggtcaaa
    10441 gctggtgtta attctgccgc ctcaatagtc tcagctacag gctgttcagt gactgtaaat
    10501 gtctttgtgg cagcatcata agcccaaacg ccgtctacac catttttatt agcatagtct
    10561 ctgaaggtct gctcagctac agctgcgtct actgccttag tagctgtttc acctgaaaaa
    10621 gttgctccct tgatgacaag cttatagcta gtcaaggctg gtgttagttc tgctgcgtca
    10681 atgacctcag aactcggtag agctgataaa atctctgcct taagcgcatt gacaccttca
    10741 acagttttgg ctttgttgat taaggtcaca tagtaatcac taatgccata ctgctttagt
    10801 tcattgatag cagcttcttt agcctccaac aaggctgctc ctgtaatgtc cgcaatagct
    10861 gtatgagcat cattaatggc tgcattcact tgatcaactg aagcagcatc tgccacctta
    10921 gctgctgcag caactagagc tagctgaacc ttttgatcgc ttttgtgctg atcacttaag
    10981 gcattgattg ttctgtaagc ctcacgtctt gcttcatcaa gctgaacacc agcaacagct
    11041 gcctttgctt tgtcaagagc tgctttagcc tgatcaacag tatctgcagc aagtgcctca
    11101 actccagcat tagcaagaac agcctgaagc tcttgattgt cagcgtagtc atcactcagc
    11161 tgattgattt ccctaacagc ttctctaatg aaggctgttg taggctctaa cactgttgct
    11221 gcgtctaaag cacccactga agtcgttcca accagaaagg ctgccgacac tgaagctaaa
    11281 ccaacagctg attgacgtaa aaagtaggat acctttttgt ttttttccat ttttcctccc
    11341 tcgctttttg taaaaaaaac tttgacacta aaaacta
//
LOCUS       DARYXZ010000061        10996 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYXZ010000061 DARYXZ010000000
VERSION     DARYXZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10996
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(32..1213)
                     /locus_tag="TV186_001745"
     CDS             complement(32..1213)
                     /locus_tag="TV186_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1533111.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TV186_001746"
     CDS             complement(1297..2532)
                     /locus_tag="TV186_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1533112.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TV186_001747"
     CDS             complement(2854..4092)
                     /locus_tag="TV186_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1533113.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TV186_001748"
     CDS             4400..6376
                     /locus_tag="TV186_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1533114.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TV186_001749"
     CDS             6440..7939
                     /locus_tag="TV186_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533115.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TV186_001750"
     CDS             7939..8865
                     /locus_tag="TV186_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533116.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TV186_001751"
     CDS             8874..9944
                     /locus_tag="TV186_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533117.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TV186_001752"
     CDS             9937..10860
                     /locus_tag="TV186_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533118.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3260 a         2144 c         2281 g         3311 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttgac
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagtat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctatttacaa
    10981 aaaacctgtc aaaacc
//
LOCUS       DARYXZ010000062        10564 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYXZ010000062 DARYXZ010000000
VERSION     DARYXZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10564
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TV186_001753"
     CDS             complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TV186_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL1533119.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1719..2432)
                     /locus_tag="TV186_001754"
     CDS             complement(1719..2432)
                     /locus_tag="TV186_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL1533120.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2453..3100)
                     /locus_tag="TV186_001755"
     CDS             complement(2453..3100)
                     /locus_tag="TV186_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1533121.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TV186_001756"
     CDS             complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TV186_001756"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL1533122.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TV186_001757"
     CDS             complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TV186_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL1533123.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6539..7321)
                     /locus_tag="TV186_001758"
     CDS             complement(6539..7321)
                     /locus_tag="TV186_001758"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL1533124.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TV186_001759"
     CDS             complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TV186_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL1533125.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            complement(8749..9381)
                     /locus_tag="TV186_001760"
                     /pseudo
     CDS             complement(8749..9381)
                     /locus_tag="TV186_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9383..10150)
                     /locus_tag="TV186_001761"
     CDS             complement(9383..10150)
                     /locus_tag="TV186_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL1533126.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQDIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(10432..10564)
                     /locus_tag="TV186_001762"
                     /pseudo
     CDS             complement(10432..10564)
                     /locus_tag="TV186_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT         3119 a         2382 c         1936 g         3127 t
ORIGIN      
        1 gattataccg ttaaataagc tgccagatca gctaaggcac gtttagcgat agcttcatag
       61 cgttcctttt tatctctgat acgaggtccg tcaagctctt taataatacc aaaattgaca
      121 ttcattggtt gaaaatgctt gctgtccgcg tgtgtaatat aataaggcag gctgccaatt
      181 gctgttgtat ttggaaaaac aagtggctct tcttccttga atagccgagc agcattaatg
      241 ccagccacaa gtccagaagc tgctgactcg acatagccct ccacaccggt catctgacct
      301 gcaaagaaaa gcctgtgatt agcgcgtgat tggaagcctt gtgtcagaag ctttggtgaa
      361 tccatatagg aattacggtg catcacaccg taacgcacaa actcagcatg ctcaaggcct
      421 ggaatcattt ggaaaacccg cttttgctct ccccatttta aatgtgtctg aaagcccacg
      481 atattataaa ggctgcctgc agcattatcc tgacgcagct gcacaacagc atagggcgtc
      541 ttgaaatcac cgtcacgtgg tcccttgtaa tcatctggat attccaagcc aaccggcttc
      601 attggaccat aaagcatagt cttaatccca cgctttgcca taacctcaat tggcatacag
      661 ccttcaaaat acttttcctt ttcaaaagca tttaaaggag cttcctctgc tgttgtcaaa
      721 gcctcgtgaa aggccataaa ctcttccttg gtcattggac agttcagata agcagcttct
      781 cccttatcat atcgcgattt taaataaacc ctatccatgt taatggttga cttatcgaca
      841 attggagctg ctgcgtcgta aaaataaaag ccagcaccac catttaaggc atgtattttt
      901 tcagcaaggc tgtcactggt caaggggcca gttgcaatta ctgtaatagc atcgctagga
      961 atgtcaataa cctcctcacg aatgatttca atcagagggt gattttcaag ctcagctgta
     1021 acagccttgg catagccttc gcgatctaca gccattgctc ctccggcagg gacacgatgg
     1081 gcttcgccag cacgcataat aatcgaatcc agacgacgca gctcttcctt taaaagccct
     1141 actgcgttgg ttaagctgtc accacgaaaa gagttggagc aaaccaattc tgcaaaatgg
     1201 gtggttttgt gttgcggtgt tgccttgaca ccacgcatct catatagctt aacaggaata
     1261 ccacgcttag caatttgata agctgcctct gatccagcta gaccagcacc aataacatta
     1321 atataagatt gagacaatag accaatacct ctttggggac ttatccatca ctgattgccc
     1381 cgcaactctt tctttcaagt aattaccctg cctattataa cagaaataag agcaaagcaa
     1441 aagaaggagc tgaacagcct cagtctttta tataaaggag ataagcccgt acctgcacgc
     1501 tctccacaaa gctagctgct tcaagcattt tagctttcgc ccaataccag ctatccacat
     1561 atcttgttca ctgcagtagt tactggaagg ctttttaagg cttatttttc aaaatctagc
     1621 caaaaatatt tcaccggacc tcatcatctt gctggtagca gctaaacaag ccttttccag
     1681 taaaaaaaaa gcaagcgaaa gcctgccctt gttcttgttt agaaaaaaca catccatgct
     1741 gcgataaaga cacttaagac actaaacagc gatccaatca aataatattc agcaaaggct
     1801 gggctttcag agattttatt gtagcgagca atagacttag cggtaagcac cagtccgatt
     1861 gaagcaaatt gtcccaacac catacaaacg cccataacaa tacgctctaa attaccaata
     1921 gccgcacccg cccctacaat ggtatccatt ggtttatcac tagctggctg gaatttattg
     1981 aagcagagct taaagataat attgacaggc ttggtgatca aaaccataaa aagcactaac
     2041 aataactgcc gagcatgtaa ccaatcaggg atctcagcct gattaacacg agcgactaaa
     2101 gccagaataa tgaaaagatg caagagctgg tccaacacaa agacccacga ccgatcaagc
     2161 ttaatgatac gagcccattt tggcttaaaa taatcaataa ccgcatggct actaaaaata
     2221 aggatcgctg ttagccaaag cttaggtata cacatcacca ctagaaacaa tggagcagct
     2281 acccctaata agtgcagccc cagataagca agctgctcct ccttcttatc agcaataacc
     2341 tgactctgaa ggtgataatc tgataaaaaa tgacaaatca ctagcagcac taaaatagga
     2401 tgctgataaa ggtaatcaga taagccctgc ataggtggct cctttcctct ttttattctt
     2461 gtaggtaggt caaagctgca tggcgacttc taagataaac ctttacactg ctgcttttta
     2521 agcgctttga caaggcactt gattggaggt ccaatgtatc gccaatgagc tgttggtcaa
     2581 attgttcttc atagatccct aagtctaaaa gcgcatgaaa cacctctaat tgactagcac
     2641 gccagctagc ttttatcgcc tcaccagctg ctaaaaggct attgagcacc agatccttgt
     2701 gctccttatc agtccgtata gctacctggg tattgccata atcatttttt tgatgaatgt
     2761 aatgaatagc ctctctggca cgccaatagg ctggaccgtc agcaccaata ctaatatcag
     2821 ggttaatatc agtcaaaata gtcccctgtc caataccaaa cctaacaggg tagcctgtca
     2881 tggcttgatt aattaaatca atgagttgaa aaacaggcgc atcattagtc aacaagcctt
     2941 gaaattcatc acccagagtc acagataagt tagagacgat ataggaagaa aaatcatggt
     3001 tgagctgatc cagacaggcc tttaaggact cttgcaccaa agaacgcgac tgaatttgct
     3061 tagaatggac caaatcccca ataacagcga tatatagcat gattttccct ccttttatga
     3121 cttccattat aacagacaaa aaccaaaaag tccattataa tggaaaatca tctatatttc
     3181 cgttataatg gacctctgct aaaatagttc aaacctactt tacaatctct tctttatagt
     3241 cacagacttc attgctacac acaacctgct tacctccacg aatttttttc tcaacaaggt
     3301 aatcgcctga cttcggacaa gaccgtccta ccggcaaatc ccacgaggta aagtcacact
     3361 cagggtagcg gtcgcagcca tagaaaatac ggttacgctt tgttttgcgc tcaatgactt
     3421 ggccttgctg acaagctgga caagaaactc caatttcctt tgtgatggcc tttgtatgat
     3481 ggcactcagg aaagttacta caagcataaa acttgccaaa tctacccagc ttaacaacca
     3541 tcgggtggcc gcacagctca caatcaaaac cagccggctc gtccttgatt tgaatttttt
     3601 cgatctccgt ttcagccttg gttaactcct taacaaatgg cttgtagaat tggtcaatca
     3661 cattctgcca ggcttctttg ccgatctcta tctgatcaag cttatcttcc atatcagctg
     3721 taaatttgac atcaacaata tcagggaaga attccacaat caattgatta acaatttcgc
     3781 ctaattccgt cggctcaaag cgtttagcag ccagcttaac ataataacga cgctgaatca
     3841 catcgagtgt tggagcatag gttgatggcc ttccaacacc gttttcttcc agtgttttaa
     3901 tcaggcttgc ttctgaataa cgagctggcg gttgagtaaa gtgctgttca ggtgttaagg
     3961 taaccttttt aaccacttct ccttctgtca tttcaggaag catcttgctt ttatcagaat
     4021 cattgtaaac agccatataa ccgtcaaatt tcatctgact gccattggca acaaaaagga
     4081 cactattttg ctctaggtta accttaacag tatcaaacac agcagctgtc atctgactag
     4141 cgacaaagcg gttccaaatc aaggtataga gctttagctg atccttatct aaaaatttag
     4201 caatagcctc tggcgtatgg ttcacattag atggtcgaat agcctcatga gcgtcttgag
     4261 caccagtagc atttttaact cgattgccat gcttagagta ctgactaccg aaacgttcaa
     4321 caataaagcc tgcggcatca ttttgagcaa ctgggctgat acgagtagag tccgtacgca
     4381 tgtaagtaat taacccttgt gttccattag gaccaagact aatcccctca taaagctgct
     4441 gagcaaccat cattgtttta cgagtccgaa agttaatctt attggctgcg tcctgctgca
     4501 atgaggaggt tgtataaggt aaaggagcat gacgcctgcg ttcttttttc tcaaccttac
     4561 taaccataaa atcatcgcta cttaatcgag acaaaacaag cttaacatca tcattggtat
     4621 tgagcttcat ctttttgcca ttgaggccgt aaaagcttgc ttggaatttt tttgtccctt
     4681 ttttaaagag accatcaatt gaccaatatt cttcaggaac aaaggcctta atctcatgct
     4741 ctctgtcaat gattagcttt agagcaaccg attgcacgcg ccctgctgaa agcccctttt
     4801 taaccttttt ccagagaatt ggcgaaatgg aataaccaac aatacgatcc agtacacgac
     4861 gtgcctgctg tgagtcaacc aaatccatat caatttttct tgggccttca aaagcttctt
     4921 tgacggcatc ctttgtgatt tcattgaaaa cgacacgatt gttatcatca ggatcaagtc
     4981 ccaaaatatg tgataaatgc catgaaatgg cctctccctc acgatccggg tcacttgcta
     5041 gataaacctt tttagcattc tttgcttctt tttttaaggc attaatcagc ggacccttac
     5101 cacgaatatt aatatactgt ggctcataat gattgtcaaa atcaatagac attgatgatt
     5161 ttttcaaatc acgaatatga ccaaccgagg caacgacctt atactgacgt cccaaatatt
     5221 tttcgatggt tttagcctta gcaggtgatt caacaatgac tagatttttt ttagcagctg
     5281 ctgatttttt ctttgtagca gatcttttcg tctcttgttt tgacttagtt gctgtttttg
     5341 ttaccaattg acacacttcc tataacagtt atggttaaag cttctagcat aatatcccat
     5401 tttttaagaa ctgtcaacaa aaaattttct ataaatagga agaaaagtta agaatagtgg
     5461 tattctgaaa gaatgtctct gccatgagtg acacagctgg caccatcttt gatcagcttc
     5521 aaacagcccg ccgatgtccc attaagaata ttgtcaggta cgacaaaaat atcacgtccc
     5581 tcttccatag ctagctgaca ggtaatcaaa gagccagagc gctgcttagc ctcaacaaca
     5641 aggacacctc gactaagacc tgcgataata cggtttcttt cagggaaatg ataagacaag
     5701 gcggcctctc cagccccata ttcactgagc acgagatgac gctgagataa aaactcctgt
     5761 agctggtgat tttcctttgg atagtagcga tctaggccag tcccgataac agctatggtt
     5821 tgcccacctg ctttcaagca agcgagatga gcactggtat caatacctct agcaagcccg
     5881 ctgacaatga caaagtgatt cttaagctct ttgatgattt tgtaaacaga ccgcgtccca
     5941 atttcactgg attctctaga gccaacgact gccagcttag gcttttctaa caggcttaaa
     6001 tcaccttgat aaaagagtaa aacaggagga ttatagattt ccctcagggc caatgggtat
     6061 tgcttatcta ggatagataa gctcggaaac tggttgaatt ccttttttaa caaggcgaca
     6121 tttaattgct tgtaggtctc aataaataaa actggatttt tgcagcaaga aaccactgcc
     6181 atatctctaa gggatagaga cttgttatta cgctgctggt agtcaatcag gttaagaata
     6241 tttaaattag ttagcccagc cttttttaat ttataaagtt caaaattatt catcactgta
     6301 cctctctaat gatttattcg taaaaaaatt aaaaaagctc tgactaaaca aagctttttg
     6361 caaactcttg aggagctgta caggattcca gcaaaaaaat cgaggcctcc tagcctttgt
     6421 atgagcattg tagggcagct catcacatag cattccattg aaaaatacca gaattgtaga
     6481 tccacctagt ggctatcgtt tttgctttcg gcagctacct tttctcaaaa tgagattttt
     6541 agcgtaagat cattgatttt atcggctcaa agctttgccg atgaattggt gtgacaccat
     6601 actggtgcaa tccctgcagg tgctccttgg tcccatagcc ggcattttta gcaaagccat
     6661 agcctggaaa ggccttatcg taatcaagca tcaatcgatc tctggtaacc ttagccacaa
     6721 tagaggctgc agcgattgac atagagctcg catcgccttt tataatagcc tgttgaggaa
     6781 tagaaacctc tagtgtcatg gcatcaatga gcaggtaatc aggcttactc acagagccct
     6841 ccagctgatt aatggcagct gtcattgcta attttgttgc ttcatagata ttaacccggt
     6901 caatggtatg gttgtcaata attccaagac cgattcccaa cgctttcttt tgaatggctt
     6961 ggtaaattgc ttcatgctta gctttaggaa tttttttaga atcatttagc cccttaatgg
     7021 tgcagccctt tggcagtata acacaggctg ctacaactgg tccagccaga ggacctcgac
     7081 caacctcatc tataccagca atcgcttgaa agcctttttg gtaaagcgcc tgttcatacg
     7141 tcaacatcgc ctcaagccgg gcttcctctt ttaagatagc ctctaaagcc ctttttctgc
     7201 tagatacagc cttttgaacg ccaagccgct tatccgcctt tagctcttca aaaaatggat
     7261 cagaaagact agaaacagct tctagacgag ctttaatgtc tttaatagtc attgctgtca
     7321 tcatcaccaa cctgatctaa ggtgtactga ccaagtcttc catcacgaat atccttgatg
     7381 aataagctgt aaaaacgatc atagtcttcc ttaaagccaa gctgacgtgt caaggacatg
     7441 atgatttctg gagcgtcagc ctctagatca atagccttaa aacgctttaa taggcgatta
     7501 ggataatact tcttaaaata attcaatcca aaaatcgtga cctcgtccat tggcaacagc
     7561 tgatccttaa tagcccctgt cagggctaat tttaacccaa ccaattcgtc ttcaaacttt
     7621 ggccataaga tacccggagt atccaatatc tctagttctt tattggattt tagccattgc
     7681 tgtcccttgg tcactcctgg cttattgcct actgtggcaa ttttttttcc cgccaagcga
     7741 ttcatcaggg ttgatttgcc agcatttgga atgccaataa tcatggttcg tagcgtttct
     7801 ttttgaatgc ctcgttctct taagcgacgt agtttatctg ccatcaattc cttagcagcc
     7861 tcggtgaccc ttttgaccgt agcctgttcc ttagcattga tagctaatgt cttaatccct
     7921 tgcttctcat aatattgttg ccatttctta gtatgcgtgt tatctgctag atcagcctta
     7981 ttaagaagca ttagcttggg cttatctcca acaattttgg tcagcatagg attttgactt
     8041 gataaaggta gcctagcgtc tactaaaatc gtcacaaaat caacatgctt aatattttcc
     8101 tgtacctgtc tccttgcctt ggacatgtgt ccaggaaacc attgaatcgt agccatgtgt
     8161 gtaaaatcct ttcgtatcaa gggtttttag cccctcgtct tttaaaaatc atgcgagtca
     8221 ccaaaaaatc accaaatatt aagcattatc tccagaccaa gcgatataat tgcaacttgt
     8281 tttggttatt tttaatgcca acaatatcaa atgatttcta atggtatctg gcttatagct
     8341 attctctgct gaatagattg cctcttcaat tttaccctgt aatctcgctc agcctgtctc
     8401 ctgaccttgc ttttacatat gaaactgtaa tattttccat tttaccagtt atatgataaa
     8461 gaaaatcaaa atagtcgtag tagaataaat tactttaaac tattatagca cgatttccct
     8521 tattttactg ctaaattatc ctttgtaaaa gaagatatta atcgttataa agaccaaaaa
     8581 agagaagacc aaaatgatcc cctctagtct tcttttcggc atattttacc gttatttggc
     8641 caactttcca ctaatgtgag taaaattgta ttctaagcaa gctttaccta ttaacttagg
     8701 agaaaacata atctctatag ctaaaaatac caaaaaaatt atgaatcatt atcgcaaact
     8761 atccatagtg atcacttcat cagccatttc ccatattgct ggattatgag ttgctacgat
     8821 gattaatctg ttagcgtcac gaagagacag tacaatctcc ataatcaact tggacgtggt
     8881 tggatctatt gaagccgttg gttcatctgc caaaataaat ggcggatttt ttaagatgat
     8941 ctttgctaag gcaactcgtt gtgactaacc cccagatagc tcaaaaatgc gtttatctag
     9001 gttcagatag gataaaccta cacgttctaa ggcctgtttc tgtctcatcg tttgctcaga
     9061 tttattcaat ttttgaccaa tgagaccaag tttgaggttt tcttcaatcg tttgattttc
     9121 aatcaaacca aaattttgga ataggtaacc caattcatga cggaaaaaat cactagattt
     9181 atagctggct aagtctttgt ctcggtaaaa aatagtccca tgataaggtt ctaatttccc
     9241 catcatgttc atcaaggttg ttttcccgct accgcttgaa ccaatcaaag catagacttt
     9301 tccaacctca aatgtcattg aaagattaga aaatagctct cgttctccaa aagatttact
     9361 cacttgttta agttcaatca tgttaacctc ctttcaaaac aagcatggac atcttgtttt
     9421 ctttctgcat ttgaacatgt aattgtaaaa gagataggcc agtgaagagc aacaatacta
     9481 agaaagcaat cactatctct acttgaagga atacactcgc aacaaatccg agtaaaaaga
     9541 cacccaattg agccaggagg taattccgat ggatttctaa aaatcttagt ccagcaatac
     9601 gtttgatgac aatggcacgt ctaaattctt caaagtagag cctattcatg gtgttaaaca
     9661 acaagattga ggttgctatc ccaagcacag ctcccgcaag cattatccaa cgttccctct
     9721 ggatattatt caacaatgtg atgtagttct ggtatcctga ttgcatttct gagacccaat
     9781 tttcaatgtc ctgtctctgg ataagctcct gggcatcgga caactgatta aagaggacat
     9841 aattctgtac cgcgtcaaac caaaacatga cggactgagg tccagttgac tggggtgtta
     9901 cgacaatgat aatcggatct ttcagaaact gttgatagga aataggtgtc gtattataca
     9961 caaaacggtc ttggcctgat tccaaataag ccaccgtcgc aatcatttgc tgtcgaccat
    10021 cttgactaga catgcgacta gttaagtcgt cttcaaaaac agatttgtaa tgttcttcct
    10081 ctgaacggag atgctcaggc aagagcaaga caaattcccc tactgcgagg tgattcagtt
    10141 tttgttcaat agccgtatct acagggatgt tttgacgctc caagtattgc ggtgtgacaa
    10201 taaggacatt gccatttggg ctgtaatctt gccattctgt agaagttgtc aagtttttgg
    10261 aaaagtctta gcctttgtta tcaatacttg agtagcacct atgtttttca gattagcttg
    10321 ctcttgtaac tgttctgagc tattaaatgc tgtcatttca acggtgatat tttcagttga
    10381 ttctgcctgc ttgttatctt cttttgttgg agattctgga cgtttctcaa aataaaaata
    10441 attataaagc tgttgagccg ttactcctcc accagcccag ccagcaacag gttgaccatt
    10501 cttcagatat agtattgttg gtgttcctgg gattccaact gttttaaata aaaactcctg
    10561 agct
//
LOCUS       DARYXZ010000063        10267 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYXZ010000063 DARYXZ010000000
VERSION     DARYXZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10267
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            6..596
                     /locus_tag="TV186_001763"
     CDS             6..596
                     /locus_tag="TV186_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1533127.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            606..2168
                     /locus_tag="TV186_001764"
     CDS             606..2168
                     /locus_tag="TV186_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533128.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHHID
                     DTFIYDGDIDLS"
     gene            2551..3652
                     /gene="prfB"
                     /locus_tag="TV186_001765"
     CDS             join(2551..2622,2624..3652)
                     /gene="prfB"
                     /locus_tag="TV186_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL1533129.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3703..4395
                     /gene="ftsE"
                     /locus_tag="TV186_001766"
     CDS             3703..4395
                     /gene="ftsE"
                     /locus_tag="TV186_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL1533130.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4388..5317
                     /locus_tag="TV186_001767"
     CDS             4388..5317
                     /locus_tag="TV186_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533131.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5707..6348)
                     /locus_tag="TV186_001768"
     CDS             complement(5707..6348)
                     /locus_tag="TV186_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1533132.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6685..9156
                     /locus_tag="TV186_001769"
     CDS             6685..9156
                     /locus_tag="TV186_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL1533133.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIGDFLI"
     gene            complement(9330..>10267)
                     /locus_tag="TV186_001770"
     CDS             complement(9330..>10267)
                     /locus_tag="TV186_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1533134.1"
                     /translation="MYVDNRLKTGSWKPDTEANKEAIYKTHFKKYLGKTKMKDISRIE
                     YENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDDNPIDGITIGDSEIIPVNKR
                     ISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVAIKIGNLTKLENGRYRILLD
                     ESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVESKRIAKKYNRILSKEDYLFL
                     TNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHMMRHFFATQGQIAGVPIEHM
                     AAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
BASE COUNT         2909 a         2018 c         2278 g         3062 t
ORIGIN      
        1 tggctttgga agggatcaca aagtcctatg gcgccaagct gatccttaag gatttttcct
       61 atacctttga acaggggaaa aaatatttga taaagggtgc cagtggtaga ggtaagtcga
      121 ctctgttaca cattattaag ggaactgctg ttgactcagg taaaatagcg tttatcacca
      181 aagacaatca ctcatttgaa agctatcaag ctaacattgg catggtgagt caggcacctt
      241 ttctctttaa tggcaccttg gaagagaata tctgtctgaa tcaggagttt tccaaggaga
      301 atatccttgc tgtcttggac caagttcacc tgttggagga attaccagct ggtctaggct
      361 ttcagataga aaataatggg accaacattt cgggcggcca gcgagtgcgc atagaattgg
      421 ctcgattttt gctacgtcag aaggatattt tattgcttga tgaggtcaca gcagccttgg
      481 acaaggacaa tgctcggcga gtaagggagc tgattttttc tcttcctatt accatcattg
      541 aggtggctca tcatgtggat caagctatag cttatgatga tatgatagaa ttgtaggtga
      601 ttaagatgtt taagtatttt aataaatatc tagtgacact aacgcttgtt gcatgtgcct
      661 taaacagtct tgtctttctg attgaaccct tgatcactag taagattttt gatttaacgt
      721 tcttaaataa tcatcaagac accttgtcct ttttaggcta tggtctgacc ttatacgtgg
      781 tcttatattc tgttatgttc attgctaatc ttctgatcaa ccatatcatg acgattgggt
      841 gtggtagaat caggttgcgt ctctatcaga atttaatctt aaattatcgg gagatgagtc
      901 atgacaagaa aatttctatg ctgactcaag atgtagaata ttatctatgg aatcacatca
      961 gccctagcat tcttctcgta tcacacgtga gtaatgtcct tttgctcagt gcttacctgt
     1021 tatcaaaaaa catgctaatt ggtcttattt ttattgcatg tgcttttgta tttttagtgg
     1081 ttcagcatgt gattggtcaa aaggcagagc aaaaaggtag tgagctggca gtagcgagac
     1141 aaaagctgct tggcttatta agtgatgtgg ttgcggggca ttcgacatta attcaaaatc
     1201 aagctctttt tgctagcctc aaacaggtaa aaaaacagtc agagcattat gagagctcac
     1261 gtcaagcatt tgagatattt aggtctttct ttaccctatt ggcacatctg atgctgttta
     1321 tttctcaatt cttgcccatt tttttaggct tagccttaac cttattaggt gttaagctga
     1381 gaacaactga tcttattgcc atgtttattg cagcaacgcg cttagaacag ccactcaaaa
     1441 atattgttga tgatatgttt aggcttaatg gtgcaaaagc cattgctaag cattttgaga
     1501 cacttttaga gcagcctatt ccaaaatacc agtcgcatgc tatgacaggt gatccttttg
     1561 aatgcttaga tggtcatcat ctggcgaaat catttgcagg taggacctta ttttccgatc
     1621 tctcttttca ttttgagaag ggaaagaaat acctgattaa gggatcaagt ggatctggta
     1681 aatccacact ctttaagctt atcttacagg agatgagtcc tgatgagggg acactagata
     1741 tggtattgac tggaggtcag acgactgata attatcacca tcgcataggg ctgattgcgc
     1801 agtcgcctta tctttttaac gatagcattc ggtataattt gaccttgggg gaggcgtttt
     1861 ctgatgagtt gcttttagaa aagctagaac aggttggctt gactgatgaa tttgacgata
     1921 ttttaaacca ccaaattgtt aataacggag aaaatatctc aggtggtcaa aagacacgtc
     1981 ttgaaatcgc aagaagcctc attagacaaa aagatgttct tctagcagat gaagtgacgg
     2041 ctccacttga tgtcaaaaat gctaaaacta tccgacagct actatttagt ttaccggtaa
     2101 cagttattga aattgctcat catattgatg acacctttat ctatgacggt gatattgatt
     2161 tatcgtagaa aatatcatca cattgcttag aaataataat tgatgcttat gaaattgtca
     2221 ttcacacagt gaatggcttt ttcttaggct aaattttcca tgtggagctt gatctgatag
     2281 gctatctgag aaaaaaagct aacaacagcc atgttttttg gggctatgac tgttctaata
     2341 cgagctgcct ctagctgctg gtatataaga ggtgacatga ttgtcacaat tcgtcatcat
     2401 tttgtcgtta aatttttaca tagatttctt atgctagtca tggcagagct ccttacccta
     2461 aaaagaaggg aatttagctg atgggaaata gcaattctaa agcctttatg ataaaatgaa
     2521 aaaagacact ataatagaag aggtaactgt atggaagtgg cagaaatgcg ccagcaaata
     2581 gtagaaaaca aagagaagtt gactagcttc aggaggtctc tttgacttag agcgtttgga
     2641 ggaggatata gctctcttag aaaataagat gacagagcct gatttttgga atgataatat
     2701 ggcagctcaa aaaacctctc aggaattaaa cgagctcaag ctcacctatc aaacctttca
     2761 tgatatgcag gagctatctg atgagacaga gctttattta gaaatgcttg acgaggacga
     2821 tagcgtcaag gaagagctag aagcaagcct gattaagctc agccagatgc tagcaagcta
     2881 tgaaatgacg ctgcttttgt ctgagcccta tgatcatagc aatgcaatcc tagaaattca
     2941 cccaggttca ggtggcactg aagcacaaga ctgggcagac atgctttttc gcatgtacac
     3001 tcgctttgga aatgccaagg gctttaaggt agaaactctg gactatcaag caggagacga
     3061 ggcaggaatt aagtctgtga ccctttctat tgaagggcca aatgcttatg gcttcttaaa
     3121 atcagaaatg ggagtacatc gtctggtgcg tatttctcct tttgactctg ctaagcgtcg
     3181 tcacacctcc tttgtttcag ttgaagtcat gccagagctt gatgatacca tcgaggtgga
     3241 gatacgtgat gatgacatta agatggacac cttccgctca ggtggtgctg gtgggcaaaa
     3301 tgtcaacaag gtctcaactg gggtacgctt gacccatatc ccaacaggaa tcgtagtggc
     3361 gtcaacagtt gaccgcaccc aatatggcaa ccgtgatcgc gctatgaaaa tgcttcaagc
     3421 caagctttat cagttagagc aggagaaaaa ggcagaagag gtcaatgccc tcaaggggga
     3481 taaaaaggag atcacctggg gcagtcagat caggtcctat gtctttacgc cttatacgat
     3541 ggtgaaggat catcgtacca attttgaggt ggctcaggtt gataaggtga tggacggaga
     3601 tattgagggt tttattgacg cttatctcaa atggcgcatg ggtgaggatt aaagtgatcc
     3661 ccactcagat aaacactaac agcttagaga aggaagaata agatggcatt aattgaaatg
     3721 aagggtgttt ctaagaaata ccgtcgctcg acaacagctc tgagagacat taatgtctca
     3781 gtcaatcaag gggaatttgt ctatattgtt ggtccatcag gagctggtaa atcaaccttt
     3841 atcaagcttc tttatcgcga agaaaagcta agctcaggca gcctaaaggt gggtgagttt
     3901 gacttaacca agctaagagg acgtgaggtt ccaattttac gtcgcagcat tggtgttgtt
     3961 tttcaggatt ataagttgct ccctaaaaaa acggtctttg aaaatgttgc ctatgctatg
     4021 gaggttatcg gagagagacg tcgccatatc aaaaagcgtg ttcctgaggt tctagacctt
     4081 gtcgggttaa agcataagat gcgctccttt cccaatcaat tgtcaggtgg tgagcagcag
     4141 cgtgttgcga ttgcacgcgc tattgtgaac aatcccaagc tcctcattgc agatgagcct
     4201 acaggcaatt tggatccgga aatttcttgg gaaatcatgc acctgcttga gcgtatcaat
     4261 ctacagggga caacgatatt aatggcaacg cataacagtc atatcgttaa tactcttcgc
     4321 catcgcgtgg ttgcgattga aaatgggcgt attgtccgcg atgaggagaa aggagactat
     4381 ggttacgatg attagacatt ttttccgtca tatctgggaa tctatcaaaa atttaaggcg
     4441 taatctcctc atgacctttg cgtcagtcag tatggtgacc gtcaccttaa ccctgcttgg
     4501 ggtctttgct gcaaccctgc tgaacattca acgtgtcgct tctggcgtgg aaaacaacat
     4561 tcaaatcaat gcttacttac aggttgattc gacagatgct gctaagatgg ttcagtcgat
     4621 taatggagag cagataaata acgagaatta ccataagatt tatgatcaga ttgcagggct
     4681 aaagggtgtt gagaggatta ttttctcaag caaggacgag cagctgcaaa agctacagga
     4741 tagtctgggc gatgtctggg gcatgtataa tgaggatagt aatcctctgc aagacatcta
     4801 tatcgtagag accaagaccc ctaagcaggt caaatcagtt accaaggcca tcaaaaagat
     4861 tcaagggatt gaagatgcgg actatggtgg tattaattct gataagcttt ttaagttttc
     4921 aaaactgatt caaacatggg ggattatcgg aacgctgttg ctcctgttta ttgcgatctt
     4981 tctgatttca aataccattc gcatgaccat catgtctcgt cagcgcgata ttgcgatcat
     5041 gcgtctggtt ggtgcgaaaa attcttatat tcgtggccca ttcttttttg aaggggcttg
     5101 ggttggtctg tttggtgcga tattgccatc gttgattatt tattatggct acgagtttgc
     5161 ctacaagcat ttcaccccgg aattacagca taatagcctg tctatgtacc ctatcaatcc
     5221 atatgtttat tatttaattg gcatgctttt tgtgattggt attatcattg ggtcactagg
     5281 atcagtctta tctatgagac gttaccttaa gttttaattg aaagagcttc tagcctgtgt
     5341 gcctggactg gtaccctgcg gttagggctc tttttgcttt tggggcaatg cttgctagat
     5401 aagcaaacaa tagcttaagc ccataccatt aagtattggg cttaagctat tgttatagtt
     5461 gtttaggtaa tagaagcagc cggaacttga ggtgtcctat ctaggtcttg agctatagct
     5521 tttctggcta gttggtgttt cttcacgtaa cagcgatttg tcgaacgata aggtgctctt
     5581 cttgtgatag ctggcttgta gtgatcgaca ggtgctaagt caaattagcc atcctgatgg
     5641 actggagtca tagcttttgc tgctgcgcct ggttgggcat agactgggca tctcggtagc
     5701 ttgagcttat cgctgcctca gaaagggatt gctatttttt tcatggctaa tggtggtagc
     5761 tgagccatgc cccggataaa tctgataatg gttaggaagt gttagcagct tatcacgaat
     5821 gctagcaagc agctgttcaa gatttccagt cggcaaatct gttctaccga tgctttctct
     5881 aaacagagca tcgccagtaa acaccgcctc ctcctgctca aagataaagg aaacgccacc
     5941 ggcagagtgt cctggtgttg gcactactga aaagtgaaat ccagctagct gataaggtgt
     6001 ctgatactga aagagctttt ctgctggttt gcagatgata tcaggcagat cagcgtgacg
     6061 tatcagtcct gacaggttca tttctggttt ataaagccag tccgcctcct ccttggcaac
     6121 atagacagga gggtgctggc agctctctct caccagctct aggctcataa tgtgatcata
     6181 atgcgtatgg gtcagtagga tagcagcaac aggcttgttg atggcatgga tttgtgataa
     6241 aatagcctgc cccttgcttc ctgggtcaat gactaaaata gcctcgtcat tgacaagaag
     6301 gtaagtgttt tcacccgcaa cgggattcat cagtgtcata atagtcatac ccttagttta
     6361 ccaaaatctg actcaaaaga cagctcaaaa ccacctcttt tgataaaagt gatctgttta
     6421 atggttttga tggctaagcc aagatagctc cagcttaaag gctgcttttt ttaattaata
     6481 ggagcaaaaa ggagctgcct cagcgctaac agctaatcag agtattagct ctctagtgtc
     6541 atagcaagga agtaggctgg ggcgattaaa aggcttgata actagctttt tatgatactg
     6601 actagcccta ttgagctgag ctaagactgg tattgtcaga tttaggcaaa gcctgtcaga
     6661 aaacgtgcta taatagatag tactatgatc aatgagtttt cacaaaaata tgctgtgatt
     6721 gacctggaag ccactagccc aggtccaaca gcgtctatta ttcaggttgg cattgtgatc
     6781 gttgaaggaa aagaaatcgt tgattcgtat caaactgata ttaatcctca tgagcccttg
     6841 tcagaccata tcaaagcact cacaggtatt acagaccagc agctagctca ggcaccggat
     6901 ttttcacagg tagcaaggac catttttgag ctgattgagg actgtgtttt tgttgctcat
     6961 aatgtcacct ttgacgccaa tttgttggca gaagccttat ttttggaggg ctatgatctc
     7021 ctcactccta gagtggatac tgttgagctg gctcagattt tttaccccag cctagaaaaa
     7081 tacagcctta gccacctatc agaggtgcta gacctaaacc tatctgatgc tcataccgct
     7141 attgctgatg ctcaggcgac tgctaactta tttatcaagc tgcttcacaa gatagagagc
     7201 ttgccaagag aatgcttgga gactcttttg ctgtatgctg atagtctgtt atatgagaca
     7261 gctatgattg tgagacaagc ccttgcagtc agtcggcctt attctacgag tgactacatc
     7321 aagattaatc agatcttgct aaaaaagccg gatcagctaa caaagcccta tcaattatcc
     7381 cagtcctttg agattaatgc agccctctta ggtcttgagg agcgccccaa gcagctcagc
     7441 tttgcaaaga ttgttgagga gactcttttt cagaccgagc cagcctttat cgaggctcag
     7501 gcaggcattg gtaaaaccta tggctattta ctgcctctcc ttgcacagaa acatcagacc
     7561 caaatcttgg ttagtgtgcc aaccaagctg ctacaggacc aaatcatggc taatgaggtg
     7621 agggctattc aggagcagtt tcacatcgat tgccatagta tcaaggggcc tgctaattac
     7681 atcaagctag acagctttca agagagcctc aatcagcttg atgacaaccg cttggttaat
     7741 cgctataaaa tgcaattgct ggtttggctt ttggaaacaa ggactggtga tttagatgaa
     7801 atcaagcaaa agcaacggtt tgcagcttac tttgaccaga tcaagcatga tggcagtatc
     7861 cagcagacct cgccctttta cgcttatgat ttttggcaac aaagctatca aagggctaag
     7921 tcagctcgct tgctgatcac caatcatgcc tattttttac accggattca ggacgataag
     7981 gcatttgcca agggtaagat tctagtcttt gatgaagctc aggccttaat gctgcagcta
     8041 gaggagctag ctcatcagcg actaaatata gctgatacgc tccaagagct tcaagagcag
     8101 ctagctgtgc caagcagctt gcttgagcaa cgcttgctag agggcattgc ctttgagctc
     8161 aatcagttaa gcagtcatta tcatcaggag gaggagaagc agcaagctca agcctcacag
     8221 catttgctgc ggctccaaga gcatgtcaag gagctaggtg ctgcagcctc tcagagcctc
     8281 aagcagctgt tcaagcagca ggaaatggat tattgggtga gcagtgagca gcaggctgac
     8341 aagcgccaaa cctttttaaa tggcagcagc aggacggtcc ttcagtttaa agcattgcta
     8401 ccggagattt ttaaggccta ctttgtctca gctactctac agattagccc tagcattagc
     8461 ttggctgatt tattgggctt tgacacttat tcttatcatc agctggctaa ggagaaaagc
     8521 actcagcaat tggttgtcat tgaccaagac atgcccttga ttaaggactt gactgacgag
     8581 gcttacacac agaccatagc agcaaggcta ttagtgcttc atcagcaaca gcaggtacct
     8641 atcttagtgc tctttaatgc taaaaagcac atgctcatgg tttctgacta tttagaggct
     8701 aatcaggtgc agcacttgac acaaggcaaa aacggtacag cctatcacat caaaaagcgc
     8761 tttgatcgtg gtgagcaatc aatgctgctg gggcttgcag ccttttggga gggagttgac
     8821 tttgttcatg ctgatcgcat gatagaggtc attacccgcc tgccctttga taatccagaa
     8881 gatattgcca ctcaaaaaat gcagcgctac ctacaggcag caggtaagca gccctttaat
     8941 gattattttc tgccgatgac gatcttaaga ttaaagcagg cgattggtcg aaccctgcgt
     9001 cgaaaagagc agaaatcagc agttttgatc ttagatcgtc gcattctgac catgtcctat
     9061 ggtcagacca ttttgcacag cctagaagag gaatttctga tatcacaaca aaatttccaa
     9121 gatagtctag cagaaatagg cgattttttg atataatgaa aaatagtaat ttttatttag
     9181 ttattttaat ttatttattt tgcaaatgtt tatttatagg catttgcttt tttgtttaat
     9241 tgataccaaa taataaaaat ctataaattg tcggggaata tatcggggga tttgttaatt
     9301 taagcatttg tataaatttc cccgactaac tagtttaaag cgctcataaa tctatcagta
     9361 acactaccag caacctcctc ctttatgtga gtatatttgc tagtcatgta acttgtagaa
     9421 tgacctagtg ctgcggccat atgttcaatt gggacacctg ctatctgccc ttgggtggcg
     9481 aaaaagtggc gcatcatgtg tggggtaaca tgcataccag atttttcatt gacagtatta
     9541 aaaagtttat agactcgcct aatagagatc ggcattccta aaagttcttt tttcgcattc
     9601 ttaaagttag tcaaaaatag gtaatcctct tttgataata tacgattata cttctttgca
     9661 atccttttag actcaacaac aacatcatca atataatgcg atgtttcaag atcaacttcc
     9721 ataaaccgct ctgatcctgg cgttttcatt cctccaccgt ttggacgatg gtacgtccta
     9781 gactcatcta gcaatattcg atatctacca ttttcaagct ttgttaaatt gccaattttt
     9841 atggcaacaa cttcgctact acgagctccg aagtaagtca tacggacaat agtataatca
     9901 tattgaatca atgacttctt ggcccatgaa tcccactctt tgaattcttc aagcgatatt
     9961 cttttgttaa cgggtataat ctcactatcg ccaatagtta tcccatcaat tggattgtca
    10021 tctagcattt tattggtgac tgcatgatta agcattgcgt tgagtactga atggatcaag
    10081 cgtaaagtgt tctttgaata attcttacgc ataccattaa tatgattttc atactcaatt
    10141 ctagaaatat ctttcatttt agtcttgcct aaatattttt tgaagtgagt tttgtatata
    10201 gcttctttat ttgcttcggt atcaggtttc catgatccgg tctttaggcg attatctaca
    10261 tacatat
//
LOCUS       DARYXZ010000064         9718 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYXZ010000064 DARYXZ010000000
VERSION     DARYXZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9718
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(221..778)
                     /locus_tag="TV186_001771"
     CDS             complement(221..778)
                     /locus_tag="TV186_001771"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533135.1"
                     /translation="MSNFWGAVQSDSDDIKYRIDSYNRYGIDGLAGKLYTNYIVGKIS
                     NDELNYGLQKIFAKLISTKMGRMVPIENNNGSPYVDSGNAGLITVLILLDPEKYKDII
                     IELADSLQFEFAQRPGYFNGMLGVAEVLLNVYSQIYKKDDYLFYAEKLLLNTSFYVEH
                     RLVEKEQFIQVFNHYIEVINESTGK"
     gene            835..2013
                     /locus_tag="TV186_001772"
                     /pseudo
     CDS             835..2013
                     /locus_tag="TV186_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            1973..3421
                     /locus_tag="TV186_001773"
     CDS             1973..3421
                     /locus_tag="TV186_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1533136.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            3449..3637
                     /locus_tag="TV186_001774"
     CDS             3449..3637
                     /locus_tag="TV186_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533137.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            3642..3899
                     /locus_tag="TV186_001775"
     CDS             3642..3899
                     /locus_tag="TV186_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533138.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRK"
     gene            4076..4645
                     /locus_tag="TV186_001776"
     CDS             4076..4645
                     /locus_tag="TV186_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1533139.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            4658..5545
                     /locus_tag="TV186_001777"
     CDS             4658..5545
                     /locus_tag="TV186_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1533140.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            5557..5913
                     /locus_tag="TV186_001778"
     CDS             5557..5913
                     /locus_tag="TV186_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1533141.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            5924..6202
                     /locus_tag="TV186_001779"
     CDS             5924..6202
                     /locus_tag="TV186_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533142.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            6199..6543
                     /locus_tag="TV186_001780"
     CDS             6199..6543
                     /locus_tag="TV186_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1533143.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            6547..6906
                     /locus_tag="TV186_001781"
     CDS             6547..6906
                     /locus_tag="TV186_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533144.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            6918..7517
                     /locus_tag="TV186_001782"
     CDS             6918..7517
                     /locus_tag="TV186_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1533145.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESSGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            7571..8026
                     /locus_tag="TV186_001783"
     CDS             7571..8026
                     /locus_tag="TV186_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533146.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            8101..8334
                     /locus_tag="TV186_001784"
     CDS             8101..8334
                     /locus_tag="TV186_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533147.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            8349..>9718
                     /locus_tag="TV186_001785"
     CDS             8349..>9718
                     /locus_tag="TV186_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1533148.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFNKAFSIIQNSVQKLSSAIPHPIKSAFTSATSAVVSFSSKITSAVSAAFNSVSSKA
                     STVADKISSSFGGRITSAVTNLATKLSTGLSNGFSRMSSSAATSLNGISQKFANTSSA
                     GERLKSTVMSIVQAFSLMAVAQKAMHALTGAIGGAVSRVDTMNRFPKTMALFGYSAEQ
                     SKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTSLALAFNNAMIGYGATTE
                     GAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAFGFGKNGVQDLKSALSDG
                     KITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHTAVVKGVAGMISAFDEAA
                     KANGMKT"
BASE COUNT         3312 a         1652 c         2056 g         2698 t
ORIGIN      
        1 tcctccccaa atcaaccatt tggctctatt tcttattcta tcagcatatt gacctattaa
       61 aagttgaaac aatattggga tcatcaatat aatattagct atacttacaa gagtttttga
      121 atgatatgta gatgcaacat aaatgataaa aacaatatta tatattgaag agccaaattg
      181 atttaaaaag gtagatatag aagtatatct gaaaaatctg ttatttacca gtagattcat
      241 taataacctc aatatagtga ttaaatactt gaataaattg ttctttttca actagtctat
      301 gctcaacata aaagctagta tttaataaca atttttcagc ataaaataaa taatcatctt
      361 tcttatagat ttgtgaatat acatttaata aaacttcagc aacacctagc attccattaa
      421 aatatccagg tcgttgagca aattcaaatt ggaggctatc tgccaattcg atgataatat
      481 ctttatattt ttctggatca agtaatatta aaacagtaat taaaccagca tttcctgaat
      541 ctacgtaagg agatccattg ttattttcaa ttggaaccat tctacccatt ttagtagaaa
      601 ttaatttagc aaatattttt tgtaaaccat aattaagttc atcatttgaa atttttccaa
      661 caatatagtt agtataaagt ttacctgcta aaccatcaat tccatatcta ttatatgaat
      721 caatccgata ttttatatca tctgaatcag actgaactgc cccccaaaag ttagacataa
      781 aatctaacaa ttggggggct atttttatgt ctaacttttg gggggcagtt cactattgac
      841 cttatgtcgg tcagaaacaa tgaggactac cacaacgtca aaataaaaac agatttatca
      901 atttatggaa gagcctacga gctgttaact gttgagaaaa tagatgacaa aaaaaccgaa
      961 gtaaaactct accagctccc ggccgagcaa acttttgtta tctatgatga tacataccag
     1021 cgaaattcgt tgatggccgt tcatttctac gacatagatt acggctcagg taaacgtaaa
     1081 cagattatca aagcatatac ttccgacaca atttatacct acgaagacta taaccttgaa
     1141 acaaaaggta tgcgattaaa agattatgaa ggacattttt ttagaggtgt accagtcaac
     1201 gaatacgcta ataacgagga gcgaacgggg gcttatgagt ctgtacttga taatattgac
     1261 gcctatgatt tatctcaatc agagcttgct aactttcaac aagattcagt caatgcgttg
     1321 cttgtaatag ctggtaatgc ttacacagga gctgatgaga atgactactt agatgatggc
     1381 cgattaaatc ctaatggtcg tttagcgatc tcaattgggt ttaaaaaagc ccaagtgtta
     1441 attttagacg ataatcctaa tccaaatggc gttaaaccgc aagcgtactt tctcaaaaaa
     1501 gagtatgata ccgccggtag cgaagcctac aaaaatagat tagttgcaga cattttgagg
     1561 tttactttta cgccagatac acaagatatg aaattttcag gagttcaatc tggtgaatca
     1621 atgaagtata agcttatggc ttctgacaac tatcgcgaga agcaagagag gttgtttaaa
     1681 aaaggattaa tgcgacgctt acgcttagca gctaatatct gggccatcaa agggaatgaa
     1741 gcaactacat atagccttgt aaatgatacg agtatagttt tcacacctaa tcttcctcaa
     1801 aacgataatg aaattgttac agctgcacaa aatctttatg gcattgttag cgatcagact
     1861 atctttgaaa tcttaaatac tgtcacagga gtagatgctg aagcagagct tgaacgcttg
     1921 aaagaagaag ctgataaaaa gcaatcttta ccggagccta gattggtagg tgatgctagt
     1981 ggtcaagaag aaccaacggc agaaaagcct taattactgg caaaagcgtc aaaaagatat
     2041 tctaagttat ttagacagaa ctgatttaga tgtcttttca gaactgcaga agttatataa
     2101 tgaacaggct tttgagttac aaaaggaatt gtttgatttt tatactaagt attctgaaga
     2161 gaacaaaatg acttatcagg atgtcgttaa aaaactacgt catgaagatt tatcagatta
     2221 cgtagctaat gctaacaagt atcgtaaaca agctgagaaa gatcctgagc tgctaaaacg
     2281 acttaatgag cagtatgtat cagcaagagc tacaaggatg gatgcattaa atcttgagct
     2341 tgtttatcgt gcggggatac taaaaggtgt acttgattca gcatttgaaa atcatttaaa
     2401 aaaagttgcc tcatatgctt ataaaaaagc aatgggtgga cggtcaggga caatcaatgg
     2461 tccagtttta gaagaactgg ttagaacccc gtttgatggt tataactatt cagaacagtt
     2521 gtggggcaat actgacaatc ttgttaagaa tcttcaaaag agattaaaac aaggttttgt
     2581 tcgtggcgag catcctagag cgatggccag agatttagct aagcgattta atgttgctaa
     2641 tcacagggct gaaacactaa tcagaactga tggaactatg gtgattaata atgctaccgc
     2701 taggcgctac ttgaatgcag gacttaagta ttatcgtgat ttagttagac ttgatgacag
     2761 gacaactgag atatgccgta caattgctaa agaaaacaaa agaaagctat tatctgagct
     2821 aaagcctgga attaatgtag caccctatca tttcaactgc agaacaacta ttattcctga
     2881 tgaagatgag ctaagtattg aagtagaacc aattgatgat aaaagcacta agtattttaa
     2941 ggatgtcacc tcagattgga tagatggaaa tgagcataaa ccacaactgt cactactaaa
     3001 tgagtacgta aaaaatggca ctccttacaa agtagatggc catagtgtcg ttcttgatca
     3061 ttcgaattat gaatatagag ttgctaattg gttatccaaa aagacaggat tgcaagttga
     3121 catggtgcca agagttaatt cccctgaaca tatcaagact cctgattatt tagttgatgg
     3181 agctcctttt gatctaaaag aaatcacagg ttcgggtaaa aacgtcattg atggcaatct
     3241 acgaaaagca aaaaagcagg caactaatat catttttgat ataacaaaaa cccctttatc
     3301 atttgaagag ataatggggc aattagaaca tatttatatg atagatcgta ggggtcttga
     3361 tatatcaatt atcaaaaata aagatgaggt attagctgta ttagaaaaag aaggaggatg
     3421 acccaccgcc tccacagtaa actgcttcat gggcgttaga ccatcatcct tctttatctc
     3481 aattatacat caccctatta aaactatcaa ggaggaaaat atgtttattt ggcaaatggt
     3541 attagtggca ctaggtgtat tggtactcat attgattgtt ggcattgcag caatagcggt
     3601 taagtcaatt attgcagaat tgaaaaaaga aggataaaac aatgaataag cgcattaaga
     3661 aaaaacgtaa attggaaaca gcggttgtga tgcttgttgc agagaatgcc atgcaagcag
     3721 aagctattaa aaatcaaaac aaacaaatca tggagctaaa atcaatcgtt caacgaaacg
     3781 ctctggcaac aaacgaagag ttagcgactg ttaaagctgc tactttagat aaccaatcag
     3841 ttatcaaggc aattggtgac acggttgact atattaagaa aaactacaaa cggaagtagg
     3901 ggaaataaag tttaaccgtg tcgaatttga cctctttaca aatctaaacc aaagtcgtag
     3961 caatacggct ttttattgtg tccaaacttt gttgatgaca ctaaaagcta cactgtttcg
     4021 tcgcaggacg taaagctaga ctatcggttg gtggcgtaac cactaggaga aagttatggc
     4081 agaagaaaat gtaacaacag agacaactga gcaagtcgac actcaaaaag aagctgttga
     4141 acatcctaag catgaatatg agcgaacttt tactcgcgca gacatctcaa aaatgatggc
     4201 tgctgaacgc actaaatggg aatctgaaca atccgcagct attgaaaaag ctcgtacaga
     4261 aggtgaacgt ttggccaagt tgtcaaaaga tgagcgcgct aaagaggagg aacaaaaacg
     4321 tctagatgct atcgcagagc gtgaaaaagc agtagcagag cgtgagatgc gcattgagac
     4381 gcattccctg cttgtggaga aaggattgcc attggatttt attgatattg ttttagccac
     4441 tactgcagaa gaggttaagg ccaatattga taatttacaa actatttttg ataaagctgt
     4501 tgaaaaacgt gttaacgatc gtttaactca gaaaccgcca cgaactggaa atggctcggt
     4561 cggtatgact aaggctgaca tcatggcgat agaggatgac gacgaacgta tgcgtttaat
     4621 tgctgagaat cgtaacttat tttaagaggg gaatattatg gctgaaaaaa acttaaacac
     4681 tatggcggac ttaggagata ttaaatcaat tgattttgtt aacaagtttt ccaaaaatat
     4741 taatgattta ctaaaattgc taggggttac tcgtcgtgaa acattaacta acgatctaaa
     4801 aattcagacc tataagtggg aagtgacttt agatcaaact gatcctggag aaggggaaac
     4861 aatccctctg tctaaggtta ctcgaactaa agataaagac tatacagtga agtggttcaa
     4921 gaaacgtcgt gcaactacag ctgaggcaat tgctcgccat ggtgcagctc gtgctattac
     4981 tgaagcagat aagcgcatta tgcgtgagct tcagaatgga attaaggatg cattctttac
     5041 attcctcaaa acaaaaccaa caaaagttaa aggcgttggc cttcaaaaag cgctgtctgc
     5101 atcatgggct aagctagcta cttttaatga gtttgagggt tccccgcttg tttcttttgt
     5161 ctctccttta gacgtagcta actatcttgg agatactaaa gtaggtgcgg atgcctctaa
     5221 tgtttttgga atgacattgc ttaagaactt tttgggtatg caaaatgtga ttgttatgcc
     5281 atctgtgcca gagggtaaaa tctactcaac ggctgtagaa aatctagttt ttgcatcttt
     5341 aaatgttaaa gggggagact tgggcggctt gtttgctgat tttactgatg agacaggttt
     5401 aattgctgca gctcgtaatc gtcagctttc taatcttacc tatgaatctg ttttctttgg
     5461 ggcgaatgta ctgtttgctg aaattcctga aggggttgta gaggcaacaa tcgaagctgc
     5521 tgctgtaccc ggcattggtg gttaaaggct atttatatgg gtgataaaca acttattgac
     5581 gatatcaaac tctttatagg tatttccaag ggtgatggtg cgcaagatga gctcatcacc
     5641 cttgctatat atgaaagtaa agagcgtgtg ctagctaaac ttaatgaata ctcagaaact
     5701 gaaatcacca aaattcctga tagattgagg tttattgtcc gtgatgttgc tattaaacgg
     5761 tttaatagga ttaattcaga aggagccgtt gaagatagcg aagaaggaaa gacttttaag
     5821 tgggacagtt accttaaaga gtatgaatca acactcagaa gcgctgctat tgggaaggta
     5881 tattcaggca aaggggtagc aagatttatt taggagatac acaatgatct ataaagatag
     5941 agtaatctta gtgtatgtcg atgaacagga cgattttcta gataaaagaa ctgttgaaaa
     6001 acctagcggg aaaatcccct gtatggaaaa tactttcaca aaatctgaac agatggggct
     6061 atttggtaaa tatgatttga atgcttttaa gttgcacttg caaggccatt acgacggctt
     6121 tagcaagatt atctacaagg gaaaatcgag gttgataaag ggactagcac accataaaaa
     6181 tagcacggtt atttatgtat gagtcttatt tatcggatga gaggcctaga taggttttta
     6241 cgcagcgttg agcgcaagca gaagtcagta cgaatcgctg tagataaaga gcttagtaaa
     6301 tcagctgcta ggattgagag acaggctaaa atactagccc cggttgacac tggatggctg
     6361 agagctcaaa tctacagtga gcaacaacga ctcttacact atagagtggt ttctcctgct
     6421 ttatattcta tttatcttga attaggtact cgtaaaatgg aagcacaatc gtttttagac
     6481 cctgccctga gaaaagaatg gcctgtgcta atggctaata tcaaaaaaat gtttaagagg
     6541 tgatgcatgg attactcact ggaaacacta tatttaaaaa aggtaaaaaa tagattggga
     6601 gttttagaca taccaatcta ttttaaattg cctaaatcag acgttttaga gccttttatt
     6661 gttgtaggta caaatatatc agacttgtca aaaacagctc aaactggagc agttattgat
     6721 gattttagcc tgaatatcga tgctttctta cctggcgata gtcgtttgga tgcagaagag
     6781 ataaaatctc gcatgcttag actgcttggg cgaaataacc aaataaaggc tcagattttg
     6841 gtagataatt caataggacg agaagtctat agagttgcta tcaacattac agaaacacta
     6901 ttttaaaggg gacctaaatg gcaaacacaa aaaaaggaac aactattgaa attacaacag
     6961 gtaaaccgat tgtaggaaaa aagatttttt actttataca atcagttgat gcaccaaaga
     7021 aaagtcaggc tctgttgcca gcctatcgta ccgatggtac tacaaccatg ggtggtgaat
     7081 acattgatga gcaaacccaa caaggtcgcg ttattgagaa ggctacagat gaacactcta
     7141 ttgatttgac aacgtacttt gtaccgacag atccatctgt tgctgtcatc gaggaagcta
     7201 agaaaacggg taaatctatc aaaatttggg aagttattgc cgacgaaagc gtcaaagaac
     7261 aaatccaaat tcctgaatcg agtggtccca agaaagatgt ttaccctgct aagtttgggt
     7321 acgccaagat tgacgaaatc gaacgtggta ctggtatttc agacttagta gaaatgtcct
     7381 acaccgctaa cattgtaggg gccttacaag atggtaaatt ccctctcacg aaagaagaaa
     7441 ttgaaatgct agaaaatgta tacggctatc aaaatccggg tgatactact ggcgactacg
     7501 ataatatcac taagtagtac acaggggcgg cgactgctgc cccattttga tttaaaaagg
     7561 agataaaata atggaattta cagcagcgaa acgaaatatc gatattaaat ttgattttaa
     7621 aactatgttt aagatcaata ataaactagg aacaattaac ccagaaacag gagagcgcaa
     7681 tgcagatggt gttggtgctt tgtttttcaa tatcttagag cgtaatgaaa gcgccattgt
     7741 tgaccttgtg cgtttatctg cgggaagcgg aaaaaaagcg ctaactgaag atgaaattct
     7801 agatgcaatt gcagaagctg ttgatgaaga aggaacaaca gaagggttgt ttgctgaaat
     7861 agagaaagaa atggttgatt ctggtttttt cagagcgaag attttgaaat atatcgaaaa
     7921 catggagaaa tcagctcgct atctcaaagc gaaggacgat acggacgcaa ctcaaatcca
     7981 aattatcgaa gacatgattg gaagaatgag caacgcagta tcttagtaaa ttgcgcacgg
     8041 ttagggctca cagacattga tactatctat aaatgtacta agtgggagct agaggctatt
     8101 atggaggggc ttgagtataa gcaggttgct gagcgcgaga acctctctga attgtctcta
     8161 aaacttagat atacattaaa tgctaaaaag gttgatgtag gtaagctcaa atatgataag
     8221 cataggctaa ctatcaaaag atcgtatcaa aaagctagcc gtagccaagc cgatagtgat
     8281 agcagtattg ttgagagaat acaaatgctt aataatcatt ttcaaaatag atagataagg
     8341 aggagtagat gccaggaaca tttgatggtt ctattttcgc tgatgttggt gccaacacaa
     8401 aggactatga gcaggccatg gctcgtattg ttagtacgac tcagaatgct ttcagaaaag
     8461 cccaagatac agcggttaac agtagtaata aaatggttca aatcattgga caaatcatgg
     8521 cccaattagc gaacaacggc gaatcgctcg gaaagagact tggttccgcc tacgctactg
     8581 gtttaaaact gagcattggt gaaattcaac gtatagcagc ttccattggc gaaaaaattc
     8641 ccgaacccat aaagaatggt ttcaataaag ctttttcaat tatccaaaat agcgtacaga
     8701 agttatctag cgccatccct caccccataa aatccgcatt cacaagtgca acaagtgcag
     8761 tagttagctt ttcgtctaag atcacaagtg ccgtctcagc agctttcaac tctgttagtt
     8821 ctaaagcgag tactgttgca gataaaatca gtagtagttt tgggggtaga atcacttcag
     8881 cggttactaa tttagcgact aagttaagta caggtcttag caatggtttt agcagaatgt
     8941 ctagttctgc ggctacttcc ttgaatggaa tcagccagaa attcgccaac acctcttctg
     9001 ctggagagag actcaaaagt acagtgatga gcatcgtgca ggcctttagt ttaatggctg
     9061 ttgctcaaaa agctatgcac gctcttactg gggcaatagg cggggcggtt agtcgggttg
     9121 ataccatgaa ccgctttccg aaaacgatgg cactatttgg gtattctgct gaacaatcta
     9181 aggcatcaat tgataagttg tcaaaaggaa ttgaaggtct gccaactccc ctagatagcg
     9241 ctgtgaaaag tgctcagcag ctcgccataa ccacaggaag tttagataaa ggaactagtt
     9301 tagccctcgc cttcaataat gcaatgatcg gttacggtgc aacaactgaa ggggctgagc
     9361 aagcactcag gcagtttaac cagtcgttgg ggtctggaaa aattcaagct gaagagttta
     9421 actctgtatc agaagctgcg ccgggtttaa tgtctaaaat ggcggaagcc ttcggttttg
     9481 gtaaaaatgg cgtacaagat ttaaaatcag ccttatctga tggcaaaatc actgcacaag
     9541 agttcgcaga taaaatgatt gagcttaacg atgcccaagg cggatttgca gagatggccc
     9601 aatcatcggc tggtggaatc cgaactgcgt ggaagaacgt acataccgcc gttgtaaaag
     9661 gcgtagcagg tatgatttca gcctttgatg aagcggctaa agctaatggt atgaagac
//
LOCUS       DARYXZ010000065         9607 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYXZ010000065 DARYXZ010000000
VERSION     DARYXZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9607
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..675)
                     /gene="speh"
                     /locus_tag="TV186_001786"
     CDS             complement(<1..675)
                     /gene="speh"
                     /locus_tag="TV186_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeH"
                     /protein_id="HEL1533149.1"
                     /translation="MRYNCRYSHIDKKIYSMIICLSFLLYSNVVQANSYNTTNRHNLE
                     SLYKHDSNLIEADSIKNSPDIVTSHMLKYSVKDKNLSVFFEKDWISQEFKDKEVDIYA
                     LSAQEACECPGKRYEAFGGITLTNSEKKEIKVPINVWDKSKQHPPMFITVNKPKVTAQ
                     EVDIKVRKLLIKKYDIYNNREQKYSKGTVTLDLNSGKDIVFDLYYFGNGDFNSMLKIY
                     SNNERID"
     gene            complement(701..1378)
                     /gene="spei"
                     /locus_tag="TV186_001787"
     CDS             complement(701..1378)
                     /gene="spei"
                     /locus_tag="TV186_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL1533150.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKAKFFSGKRVDIFTLEYSPPCNSNIKKNSYGGITLSDGNRIDKKN
                     IPVNIFIDGVQQKYSYTDISTVSTDKKEVTIQELDVKSRYYLQKHFNIYGYGDVKDFG
                     RSSRFQSGFEEGNIIFHLNSGERISYNLFDTGHGDRESMLKKYSDNKTAYSDQLHIDI
                     YLVKFNK"
     gene            complement(1652..2986)
                     /locus_tag="TV186_001788"
     CDS             complement(1652..2986)
                     /locus_tag="TV186_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL1533151.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            complement(3103..3330)
                     /locus_tag="TV186_001789"
     CDS             complement(3103..3330)
                     /locus_tag="TV186_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL1533152.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            complement(3327..3599)
                     /locus_tag="TV186_001790"
     CDS             complement(3327..3599)
                     /locus_tag="TV186_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533153.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            complement(3611..4222)
                     /locus_tag="TV186_001791"
     CDS             complement(3611..4222)
                     /locus_tag="TV186_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1533154.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            complement(4219..4656)
                     /locus_tag="TV186_001792"
     CDS             complement(4219..4656)
                     /locus_tag="TV186_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1533155.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            complement(4668..6554)
                     /locus_tag="TV186_001793"
     CDS             complement(4668..6554)
                     /locus_tag="TV186_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1533156.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            complement(6569..7687)
                     /locus_tag="TV186_001794"
     CDS             complement(6569..7687)
                     /locus_tag="TV186_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1533157.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            complement(7687..>9607)
                     /locus_tag="TV186_001795"
     CDS             complement(7687..>9607)
                     /locus_tag="TV186_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1533158.1"
                     /translation="NAVNGERSVSGEIYTNSDVLNNIDRGWRLRFEDEYYVVIYAKPV
                     DVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTIDTYLETVFKGSGYRYKLEVGVN
                     AFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLLKNIGTDLSTVVRKNFNMNDLT
                     IEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPLAKEYGRLEGAPLTDERFTVAD
                     NLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVAGDYIMAINETLGFQERIRIVS
                     FTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSRINQIDADIASAIEVATQALVS
                     ADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTRMYFWNGAEWEEPEVVNDPERW
                     REDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAALKNLALPEEAIKKITEAIKVDD
                     IPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRYNKNLLVGEPNRVKKIDEDFIE
                     VEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANNKGVKLVLTPTKAKMEPETFTL
                     IKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRNMALGMSYRDVVDGNNADLILD
                     WAENPDIIFDGNGGI"
BASE COUNT         2541 a         2099 c         1662 g         3305 t
ORIGIN      
        1 gtctattctc tcgttattgg aatatatttt tagcatgcta ttaaagtctc cattgccaaa
       61 ataatacaaa tcaaaaacaa tatctttacc tgaatttaaa tctaaggtaa cagttccttt
      121 agagtatttt tgttcccggt tattatagat atcgtatttc ttaatcaata actttctaac
      181 ttttatatcc acttcctgag cggttacttt cggtttattg actgtaataa acataggcgg
      241 atgttgttta cttttatccc acacgtttat aggaacttta atttcttttt tttctgaatt
      301 agttaatgta attccaccaa acgcttcata cctttttcct ggacattcac aagcctcttg
      361 tgcagataga gcataaatat ctacttcttt atctttgaat tcctgtgata tccaatcttt
      421 ctcaaaaaaa actgacaaat ttttatcctt gacactatat ttcaacatat ggcttgttac
      481 aatatctgga gaatttttta tactatcggc ttcaattaag ttagaatcat gcttataaag
      541 cgattctaga ttatgtctat tggttgtatt ataagaattt gcttgaacaa cattggaata
      601 taaaagaaat gacaaacata taatcatgct gtagattttc ttatcaatat gtgagtagcg
      661 acaattatat ctcatttttt ctccttaaga agtgagagtt ttatttatta aatttaacta
      721 agtatatatc aatatgaagt tgatcagaat aagcggtctt attatcactg tattttttta
      781 gcatactctc tctgtcacca tgtcctgtat caaaaagatt ataagaaatt ctctctccac
      841 tattcaaatg aaaaataata tttccttcct caaagccaga ttgaaatcta gaggagcggc
      901 caaaatcttt aacatcaccg tatccgtata tattaaaatg tttttgaaga taatatcttg
      961 atttcacatc aagttcctga atagtaacct ctttcttatc agtactcact gtacttatat
     1021 ctgtatagct atatttttgt tgaacgccgt ctatgaaaat attaacaggt atattttttt
     1081 tatcaattct attaccgtcg cttaaagtaa tacctccata tgaattcttt tttatattag
     1141 agttacaggg aggagaatac tccaaagtaa atatatccac ccttttacca gaaaaaaatt
     1201 tagctttttc tacgctatta agttctactt ttaattcaat cgaactattg ccataaggaa
     1261 tatttttgta gaacaaacta cctgaaaatg gcggaccttc atttattttt ccttttactt
     1321 ctgttggatc atatgtagag tataaattcc ttaaattaat aactcccaca ctactcatct
     1381 catacgcgta acacgttgga attatagctg atataaatac ccacaataga aaagatgaag
     1441 ttaaaaactt tttaaaatta acatttacaa tttttctcac ttataagtgt accctattct
     1501 tctttaataa taagaaatca caaaatattt tagcacaaaa aagaaaaaaa tcaacgaaaa
     1561 tgcttaaata acaattaaaa tctttataac aaaaacagcc cccgcaaaag cgagggcatt
     1621 tgtcttatct aaaggagctt tacctcctat tttatacttg tgttgcatta gataaatact
     1681 tatcttcgac ccactggtca gactgagaag cgttaatacg tgaccatcca ttcacttttt
     1741 catagactct tacacgagtt cctgccttga taaattcttt atcagcgcta cttgcgtttg
     1801 gcttagactc tacataatag tctgtgctaa gggttgcttc gtagtaaggt acattcgagt
     1861 tgtctaattt agtgttagta tctagctttt gattaaaagt aagctggctt tgtggtttgt
     1921 caatcttagg tatatccact ttgctactat catctgctaa taatacaata tttttatcta
     1981 aaccacctgc tactcctaca cttgtgaact gccaccagcg cacaccatcc attgaaggga
     2041 agaactccca aagtggctct gttcgtactt cgtagtctgg ataaccagct atccaaatgc
     2101 tgtttgggta cttagcgata atttgctgat aatcaatatt attaagcgta aatggtttat
     2161 agctgtaata aacaggctta tatccagcgt ttgcaatttt atccataaac gcaataactg
     2221 cattagtgtt agcttctttg tcggcacttg cagagtcttc ataatcaatg actaagtaag
     2281 agactttttt ggttggtaaa ttggacagaa ataaatctgc ttctcgttgc gctaagttgc
     2341 tatctcctcc aaatcgtcca aagtgataat aaccaatagg gtcactagta ttagcttgtt
     2401 gctgatgcct atcagacagc caagcgagtg actcggatac tttgataatc gttttagtag
     2461 tgccagcttg ctgacaagta gcggttaagt ctgcttgttg ataagctgat acatcaataa
     2521 aataatcgcc tttatttagt cctatattac ctataacagt aactgcattt ttaaaaactt
     2581 ttggtctaaa tgcagtagga taagtcgttg aatatggtat ttttactaaa ttatatgctc
     2641 cgtttgctcc accctggttt tgacctaaaa accatccgta tccactacct gcatcactat
     2701 caaaaatagc cacatggcta tacggtgtaa cacctgcaac taccataaaa attgcgacat
     2761 ctccagcttg catagtctct acttcgtcaa agtagtttaa aataccattt ttgtgacgtt
     2821 gttcccatat atcccttgca tatcctgtat ttgtacagtt tgcgtatggc agtcctagat
     2881 acttacagta gtctgcgtag ccatcccaac attgcgcacc aagcgatcca tcaatatcgt
     2941 aagcattgcc atttgaacga cttttatatt cctgatatgt agccatttat ccctccttat
     3001 ctaaaaatgg gcttaaaatc aaagcaacaa cagataatgg cacatacagt attgctattg
     3061 ctataactaa tgctaatcgt gtgattgccc gcatgtcccc tcctattgtt ttggttcgtg
     3121 gtaagtcaaa gcttgctcac tgtctgacag gcctttcgtg gttggatctg tgacaacacc
     3181 gagcaatacc aaaagcgtta cagctgtgtt tgcaatatcc gcgatgtttg atggtagttt
     3241 aatacctaat tgctgtgcca gtaaaaagat agctcctaaa atagccatca aggttacttt
     3301 gttttgtagt cgtaatttta aattgatcat gcttcacctc tcataatatc tttaagttct
     3361 cttacctcac gattgaggtt tttaatttgc tctgtcattg tgatgagcgt tttgttttgc
     3421 tcatcatgct cctcaagacg ccgagcattt tggcgtgtaa caatttttaa atgctctact
     3481 tcagactgca acaaagtaat atctgtcgca tgcttgatgg attttgcatt aaaaatattg
     3541 taagtcgtga cgatagctaa aataaagcca ccaagaccaa atatcaactc tgttgccata
     3601 gcttacctcg ctaatcctgc ttaactaagt ccgcatactt aatgactgtg actttatcct
     3661 cttcctctag ctctttaagc gtctgtttgt cataagtaaa cggctcgtta acgtgtacaa
     3721 agacaagatt accttctccc gcttgatctt cgtgcgactc atctacaaca gtaaacacgt
     3781 cataagcctg atactcgcct tgtttagcag gttcaataag ctctaacata cctttgtaga
     3841 tatcgggttc aactttccca ccacttgtca atacgtggat ggtttgcaag ttaatcatcc
     3901 gctgtgtacg ctctgcggac accttagcta atcctgcggc tgtttgggct gttttagcgg
     3961 tcttagcggt ttcctgtgag attttttcaa ggtcgtctac tttttgcacg gcttcgccca
     4021 tagcgatttc gacgtattca gattttttaa attcttccaa agtagctttg ataatctctg
     4081 tgtcattagt tgaagttaag ccctgcttga ttggttgaga gatgactgag ccatcctcag
     4141 cagtgataat aatatgtgtg cttgcgactg ctcctgtgct gtcaaattgt gggtattttc
     4201 ctgtcacttt ccaatttctc atggtttttc tcctttttta ctttcttcaa attgttccaa
     4261 aatgttgtcg ataagaatga tttcagatga tgtaaattca tcttcacact cttctaaaaa
     4321 gtttaaaaag tcaataaatc gcttggagta ctcaccccct ttaatcacaa tttcttcatc
     4381 agctagctcg ttgagtaggc cgttgaactc gtcgagttta gcggggtctg ctagcttgat
     4441 gtttttgtgc tcatcaatga caaacttgcc atctttgtct ttttgagcat acagatcaat
     4501 aaggtcaccc tcatccttgg cgtactcttt gaatttatcg actacttttg cgagtagctt
     4561 agcacgtccg cggtttgctc gcatgttcgt gactttgatt ttgtctagta cactatatag
     4621 tgtgtttaaa tctttgtttt taagcgttaa atccattgtt tctcctatta aattttgttg
     4681 atatgattat ttaactcgtt agtgaccgca cttgtaaaat tgctatgagc agtattccag
     4741 ccgacgttag ccaagtgccc ccaacagcgg cctaaggcta ctacagccgc atacaagtcg
     4801 ttcatgtcaa gcattttttg catcttgtct ggtctaaatt taaatcctcg attgatgcta
     4861 aagtcatctg caatcaagac attatcaccg tatagctcgg tttggtcgac tgcagcagta
     4921 tgattatatc ccgtagcgta cctaaatgac cttagccctg caaaacgacc ggaagaagcc
     4981 gagttaacac cgtcaccaga tgaggttatc ccgatcgatg catacaacgc tgaccctgta
     5041 taacctttgg gcgtcgcatt actaaaatgt acaaaggcag tatgtgtgcc atctttacgt
     5101 actaaggcat tgtttttgct attaaaatta attgtggcat cgctattaaa gtccatctta
     5161 gctgtattta agtcgataag catcgctcca ttacgagcct taatgacctt accctcgagc
     5221 aaatcagtga tagcatagcc aattttagct ttgataaagt tagcgtctaa accaacgata
     5281 ctacttgcgt taaggttaat cactctaatc ctagcagcgt caatcgtgcc tgcaataatc
     5341 tgatcagccc taatcttgat agcctctgct atctttgtgg taaaggtgcc gttgacagtc
     5401 gtattgccat cgagagcgat gtgtttacct gcgattgtta ctccgtagga gttgaggtta
     5461 attgctgaga taatctcatt accagacatt ttggcattaa tgccgccagc cttttggata
     5521 gctaatttaa tgctgtctcc agcgccacta ataatactca tgacaccatc tctagtaacc
     5581 cgctgctcaa tttgtcctgc tagttgagta aggcgcgatt ggattttacc agtcggagat
     5641 ccaacgtcgc tctgtagccc tctaaccgta tgggtcaagc tactatagtt ttcttctgcg
     5701 tcctgcatcc gcctttggta actctccaaa ctctgctgca cacgactgac agcaccttca
     5761 cggtctctaa tctcttgaga gatttggcta gctgttgact gctgtaccgc tcttagcccg
     5821 ctaatttgtg actcgagctc tgtcctcgtg ccttgatttg agcgagtaaa ctcagcacgt
     5881 aagcccgcaa gcttactctc gtaggcctct gtagtgccgc ttgaggttgt tgtgatctta
     5941 gccgatagct tgcgcaactc atcatcatac ttttgcgata gcccttgtgc tgaggcttta
     6001 atctcagctt gtaaaccgat tttatcattg gccattgtgg cttttagccc ctcgatgcct
     6061 gcctgatagc ttgcggatag cttcctatca gcatctcgat actcacgcct gataccatca
     6121 atggtgtcat tgatgagcgc tagcttttta tcagtatcct cgctgatacg tgtagcgaca
     6181 cctctggcgg agttgactat ctcggtcttg atcttaccgt cgtagtattc ctgcaacata
     6241 ccacggttag tcagcttgat ttttgaccaa agctgggaat tagcagtatc tgtcagctct
     6301 aggctaatct ctttgaggtc tttaaatagt ccagtcggat tacctgtacc ctcaactact
     6361 actggcgcaa catagctagt agcttggtct cctcgctcaa tcatgagctg attaaaatgc
     6421 gctgtgccta gacacttgct agctagtctg acttttgggt tgtcgtcctc tgcggtaaat
     6481 gtgtaatgca cacgtccatc cttaccaata acgaggtttg actcgtctaa aataagtgtt
     6541 gggtctctgc tcatttatcc tccttaatct atttttttag tatgagtttt tttaactcag
     6601 aaattgcttt atctacataa gctttggttg ccgcatgatc attcgctgtg gggtccttga
     6661 gtttcaggtt gccatcaatc tgcgaagttt ccttggcata aaaaccaccg tcagacttga
     6721 cgtagaactt atcatcacta aggtttctaa tcctaagcaa cttccctgtc gtgcctgatg
     6781 ttgagttaat gtagattcct tgagcagcag taccttttcc gcctttctgt tttttaacga
     6841 tatcaataga taacgctgta gcgttttcat cgtattttgc ctcaacgttt gggttttcgt
     6901 gtgtgatttt gagcgttcct agcgcttttt ctgaccctcg tagctgcatt gcactaccat
     6961 tttcattgtc gctagtaata ttaagcgccg atgaaaaatt gggggtggtt ggctgacgca
     7021 tcacaatatt aacggcattt gttgttccct tataatcgac aaaaagcgct gatttattga
     7081 aggtctcttt acccgtccgc aagctcatta acggcccatc actggtatca ttgttagaat
     7141 agacaacaac accagcacct tccgatttag acatatcaat gttaatcgct cctcctacgg
     7201 aagatgaggg tttaatacca cttttattag gtttaaactg tagttgtcct gtcactatgc
     7261 cgcctgtcaa actcaatttt ttgtctagct ctatttttga ctctgctttt gagtaaacag
     7321 cgcttttatc tgctttgctt gattctaatt tggtgatttt actattagtt tctttttttt
     7381 gtgcaaacgc atctagattt ggtttatttt ggagttgatt ataatctgtc gttccaggct
     7441 tgccagcagg gccccgagga ccaattgggc cagttaggcc tctttctcct gaaggacctt
     7501 gaggtcccat agggccgcgc aagtctttta agtccttgaa cttatttttg ccatcaccaa
     7561 cttttgggta acccgtagtc atatcaattc caatttctcg ctccattaag atatcggagc
     7621 ttgattccca ctcttgtttg gtcatgcctc tatgctgtat ccttgctgat gcaacttctt
     7681 ttgacattaa atacctccgt ttccgtcaaa aataatatct gggttttccg cccagtccaa
     7741 aattaaatca gcattattac catcaaccac atctctataa ctcatcccca gagccatatt
     7801 tcgcacctcc gacgcattta aatctacttg cttagatttg taccagtcac cacttaaagt
     7861 gactgagtag ctcaaaggat agacgttgat gacctctgtg tccttaatta gagtaaaagt
     7921 ctcaggctcc atttttgcct tagtaggtgt cagtaccagt ttaactccct tattattagc
     7981 ttggatcagc gtgatagcca cttttttgag cggctcacat gtctgactaa agctgattgt
     8041 gtaagtctcg ccacgcttga aaccaccatc attagcttct acctcgataa aatcctcatc
     8101 aattttttta acacgattag gctcaccgac cagcaaattt ttgttgtagc gtgtcttacc
     8161 gttgttccct aaaatttcgg cagttaaacg agattcttcg cttgtctcac tcactctatt
     8221 tttgaggtca tcaaagcttt gtttaataga cgggatgtca tcaactttta tagcctctgt
     8281 gattttttta atcgcttcct ctggtaacgc taggtttttg agggcggctc taaattcttc
     8341 aagctcttta tcggtgcgtt ggttgatttc ttcctgtgct tttttggctt tttcgatcgc
     8401 ctcagagatt tgtttttcga ggtcttcacg ccatcgttct gggtcgttca caacctcagg
     8461 ttcttcccac tcagcaccat tccagaaata cattctagta gtatcgccaa cttttaggaa
     8521 taatatgtct ccttttttta aggttccttt tggttcatct ttgggcattt ctgtgccacc
     8581 gtaaacagta tttttcccgt cagcagatac tagtgcttgt gttgctactt caattgcaga
     8641 agcaatatct gcatctatct gattgattct actgtttata gacagacttc ctacgctttg
     8701 ttttttcaca gatccgatat cattacaagt gacttcatgt tttactaaag ctccagttgc
     8761 gtcgtagtag cttgtaaaag aaactatccg tatacgctct tgaaaaccta aagtctcatt
     8821 tatcgccata atgtagtcac cagcaaccgg cctctcacat ctatacccag ctctcgttaa
     8881 atcttccata tcaattttta ctgatatctt atatgaattt tcaacattac tttttaaagc
     8941 ttcttttaga ttatctgcca ccgtgaagcg ctcatccgtc agaggcgccc cttcaagtcg
     9001 accgtactcc ttggcaagag gactttcgta ttccgcctca agtctcccct tagagtggtc
     9061 ctctgggtcg gtccatgcac caaagccttt ctgataggta ataaagctat caatattctt
     9121 ttcaatggta aggtcattca tgttgaaatt ttttcgtacc actgttgaca gatcagtacc
     9181 tatgtttttt aatagccgaa caactttccc gctgactgaa aattcaagtc cggtcgcttt
     9241 aataatctca ttgaataaat ctaacctgga cttataatta aaagattgtt ttctaaatgc
     9301 gttcacacct acttctagct tatagcggta cccactacct ttaaatactg tctctagata
     9361 ggtatcaatg gtatgagacc catctccgag accctcatag atactactct tgctgaagtc
     9421 ccaaaaaaat tggtgtatgg catcaaacga aacttgcgtt ttttgaccaa catcaacagg
     9481 ctttgcgtaa ataacaacgt aatactcatc ttcaaatcta agtcgccacc ctctatcgat
     9541 attattgagg acatcactgt ttgtataaat ttccccgctc actgagcgct caccattaac
     9601 agcatta
//
LOCUS       DARYXZ010000066         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYXZ010000066 DARYXZ010000000
VERSION     DARYXZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            101..1027
                     /locus_tag="TV186_001796"
     CDS             101..1027
                     /locus_tag="TV186_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1533159.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TV186_001797"
     CDS             1135..2421
                     /locus_tag="TV186_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1533160.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TV186_001798"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TV186_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TV186_001799"
     CDS             2977..3189
                     /locus_tag="TV186_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL1533161.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TV186_001800"
     CDS             complement(4085..4225)
                     /locus_tag="TV186_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533162.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TV186_001801"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TV186_001801"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL1533163.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TV186_001802"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TV186_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TV186_001803"
     CDS             8213..9118
                     /locus_tag="TV186_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1533164.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2534 a         1730 c         2096 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 atctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYXZ010000067         9062 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYXZ010000067 DARYXZ010000000
VERSION     DARYXZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9062
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            71..316
                     /locus_tag="TV186_001804"
     CDS             71..316
                     /locus_tag="TV186_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1533165.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            364..945
                     /gene="amaP"
                     /locus_tag="TV186_001805"
     CDS             364..945
                     /gene="amaP"
                     /locus_tag="TV186_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL1533166.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            955..1143
                     /locus_tag="TV186_001806"
     CDS             955..1143
                     /locus_tag="TV186_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL1533167.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            1156..1695
                     /locus_tag="TV186_001807"
     CDS             1156..1695
                     /locus_tag="TV186_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1533168.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            1733..1930
                     /locus_tag="TV186_001808"
     CDS             1733..1930
                     /locus_tag="TV186_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1533169.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            1940..2428
                     /locus_tag="TV186_001809"
     CDS             1940..2428
                     /locus_tag="TV186_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1533170.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            2584..3225
                     /locus_tag="TV186_001810"
     CDS             2584..3225
                     /locus_tag="TV186_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1533171.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(3342..3890)
                     /locus_tag="TV186_001811"
     CDS             complement(3342..3890)
                     /locus_tag="TV186_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1533172.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            4013..4714
                     /locus_tag="TV186_001812"
     CDS             4013..4714
                     /locus_tag="TV186_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533173.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            4726..7365
                     /locus_tag="TV186_001813"
     CDS             4726..7365
                     /locus_tag="TV186_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1533174.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILASHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            7441..8037
                     /locus_tag="TV186_001814"
     CDS             7441..8037
                     /locus_tag="TV186_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1533175.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            8047..9009
                     /locus_tag="TV186_001815"
     CDS             8047..9009
                     /locus_tag="TV186_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1533176.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         2614 a         1568 c         2127 g         2753 t
ORIGIN      
        1 tttatattta atttatgtag tcactttaaa gagtgaacaa agtagtttta ttgaattgag
       61 gagatttatt atgggaatta tttggacatt aattgtgggt gcacttatcg gtgctattgc
      121 cggtgcgctt actaaaaaag gcggatcaat gggctggatt gccaatatcg ctgcaggact
      181 tattggatca tacgttggtc aagctttgtt tggcagctgg ggtctaacat tagctggcat
      241 ggcacttttc ccatcaatca ttggtgctgt tatcgttgtt atcattactt cttttgtact
      301 aaataaatca aactaagggc atttctatca ttatagagat ggttgagtag gaaagaggtt
      361 tttatgtcga aatttttaaa aattagctat agtctcattg gcttagtcct attgacggtc
      421 tttggtggcg tgatagccat aactggagat tatattaggc tacctattgg ctatcaatgg
      481 cttcactggg atatgaattg gcttcctaaa ttcctaaatc cggccttata ttactattac
      541 ttttgggcag ctatcgcttt atttctaata acagtgctga tccttcttgt gattatcttt
      601 tatccacgca cctatactga gattcagctg gctaaggata aaggaaccct gcttttgaaa
      661 gggtctgcta ttgaaggcta tgtagcagct gctattaaag cagcagggct tatgtcaagc
      721 ccaagagtta ccgctaagct gtacaagcgt aaatttaagg ttaatgtcag tggacaatta
      781 gcttctcgcg tagctgtcac tgagcagcta aatggcatta aagaaggaat tgagactggt
      841 ttaacagaat tctttggtat taatcgacct gtccatttca aggtttatgt caaggatatt
      901 gctgatgcta agcaaaagca tagctctaag agacgtgtag aataggagat tatcatggca
      961 ttttatgaac ggtttaaata ccctattatt ggtggtctga tagggctgat agctgctgta
     1021 ttactgatga cctttgggtt atttaaaaca ctgctggcaa ttattttcat tattttagga
     1081 gtatatggcg gcctgtatgc caaaaagaca ggtattatcg atcaattgat caaacgtaac
     1141 taaaggagat ttatcatgac tgaaacttac attaaaaaca caactcataa agaaccaact
     1201 tcagctgttc gtggcgaatt gacctatgat gacaaggtca ttgaaaagat cgttggcttg
     1261 gctcttgaaa acattgatgg cctactaggt gttaatggtg gctttttggc caatctaaaa
     1321 gacaagcttg ttaatagtga ttctgttcgt gatggggtta atgttgaggt tggtaaaaaa
     1381 gaggttgctg ttgatttaga cattgtagca gaataccaaa agcatgttcc aaccattttt
     1441 gatgcgatta aatctgtcgt agaaaatgaa gtcaagagaa tgacagattt agaggtgatt
     1501 gaggttaatg ttaaggttgt tgacattaaa accaaggagc aatttgaagc tgataaggtc
     1561 agcctacagg ataaggtgac tgaggtagct cgctcaacct ctgaatttac aagcaagcag
     1621 gtagacaatg ttaaggcatc tgtaggtgca ggtgtagaaa aggttcaaga gcaaactgag
     1681 ccacgcgtta agtaagctag gctgtcaaac gatagaaata gaggaaatca taatgtcaga
     1741 agaaaaggta aatgcaaaat tggagcaagc aggcggtaaa atcaaagaag cctttggaaa
     1801 ggtgactggt gataaatcct tagaaaccga aggtaaggtt gatcaagcag ccagcaaaat
     1861 caaagaagta gctgctgatg ctaaggacgc tgtcaagggc tttgttaagg gccttaagca
     1921 agataaataa ggagttgtaa tgaaagcaaa ggacataaaa agtacgttga cctacgatga
     1981 taaggtcatt gaaaaaatcg ttggacatgc tttagagaag gtcagtggct tattagcagt
     2041 caatggtggc tttttctcaa atatcaaaaa taacctagtg aatagtgact ctgttcgtga
     2101 tggggtgtct gttgaggttg gcagcaagga agtggctgtt gacttagata ttgttgttga
     2161 atatggtaag gatattccag caattgttga gtctatcaag gctattgttt ttcaaaatgt
     2221 cgatagcatg acacatttga gggtcgttga agtaaatgtg aacgttgttg atattagaac
     2281 caaagaagag catgaggctg ctagcgtcac tgttcaagac aggctaacag acgcggcctc
     2341 agcaacctct caatttgtag ctgagcaagc agacaaggta aaagaaactg tctctaaaac
     2401 cacagataat aacgagacag tagaataaaa cacaacaact aaaactcctg ttaatgacat
     2461 attgtgggct ggtgtgatga ccagctcttt ttatcagtgc ttgaacaatg ttatgctatt
     2521 gtattctctg tgaaaatgtg atttaatggg aatggtatca tttgttaaaa aggagtaatt
     2581 atcatgacta gtaataagag agagattact aattccaagt atcaaaagat tgccatttca
     2641 gttgctgaaa ggattgccaa tggcgaatat gaagtgggag aaaagctaaa gtctaggaca
     2701 accattgctt cgacctttaa agtttcgcct gaaactgcta gaaagggtct gaatatttta
     2761 gctgatctga agattttgac cttaaagcat gggagtggcg ccattgtctt gtctaaggaa
     2821 aaggctattg attttctgaa ccaatacgaa tccacccatt ctatcgctgt catcaaagaa
     2881 aatattcgcc ataatattcg tgagcaggaa aaggcaatgg agcatttaac agtgcttgtt
     2941 aatgagtttc tgatgcaaag ccaatcaatc agcaagcaat acccgctggc accttacgaa
     3001 attatttgta gtcaggattc agagcatttt ggccaatcca ttggtgattt gaacatttgg
     3061 catcaaacgg gagcgacgat tgtagctatt gagcatgatg gccaattcat tgtttctccc
     3121 ggtccttacg ctgttatcga aaaaggtgat catatttact ttgtcggtaa tgaggacgtg
     3181 atttctagaa tgaaaacctt ttttaatgtt agaaagggtc tgtaatcaca aaaaaacaca
     3241 gagctgcttt aaggtgatgg tgatatcacg atgaagtgtc tctgtgtttt tgtgttatca
     3301 ggctaaggct tctaagtagc ttatagctct gattgaagcc cctagattac tttttcaaag
     3361 ccaacagttt tcaggataat agctgtcatg tcatcggttg tttcttgaca gtcatgacta
     3421 atccagtagc taatcagact ttcaatactg gctagataaa cctcaagcgc gtagtgataa
     3481 gggatctgat agtgcttggt gatgatttct tgaaagccat caatagtggt caaaaattga
     3541 taaataaaat ccttgagtat ttgtgaaaaa ttcaaataac tggagttagc catagcagca
     3601 ataaagggaa gattatcaat gatataagcg agggcttcct ttagaacgag tctagtatct
     3661 gtaaaaatat gagggtcatt taggagctgg tataaatcgt ctaaggtgtc atttatgaga
     3721 tgagtcatca tatcatgttt atccctgtaa tgcagataaa aggtgcctct attgacacca
     3781 gcttttttgg ttaagtcaga aacggtaatg gtctcaaagc tcttttctgt caaaagactg
     3841 acaagtgcct gcttcaaata ggccttggtt ggtgtgtgtc ttgttgtcat cgactcatct
     3901 ccttaagtca acaaatgctg cttatctgtt cttgttaaag tcttgaggac attatataat
     3961 aaggctagta taaaatcaac aaggtgttga tataaaggag gtgacatgat cagtgtccta
     4021 tattgaaatg aggtcctctt caaagaccta ccagattgga gaaacaactg ttaaggctaa
     4081 tgatgaggta tcctttgaga ttgaaagagg ggagcttgtg atcattttag gagcctctgg
     4141 tgcaggcaag tccacagtgc ttaatatttt aggcggcatg gatagcaatg accaaggtca
     4201 ggtcataata gacggcaagg acatctcgac ctatagtaaa aaggcattga ccagctaccg
     4261 tcgttacgag gttggctttg tttttcaatt ttacaatctg gtgccaaatc tgacagcaaa
     4321 ggaaaatgtt gagctggcgg ctgatattgt ggcagatgca cttgatccga ctactgtctt
     4381 aaatgaggtg gggctaggag gacgtttgga gcatttccca gcacagctat caggaggtga
     4441 gcagcaaagg gtgtctattg ctcgtgcctt ggctaaaaat cctaagttgt tgctttgtga
     4501 tgagccaaca ggggctttag attatcaaac cggcaagcaa attttaagat tgcttcaaga
     4561 tatggcgcac gacaagggca ggacagttat tgtggtgacg cataatactg ctctagcgcc
     4621 tattgctgat cgggtcattt atatgcatga cggtcgtgtg accaagacag tgcttaataa
     4681 gcagccgctt gatattgata ggataacgta ttgagaggtg cctagatgaa acaaaaaacc
     4741 ttatggaagg atagttttcg agcaataaaa gctagtaagg ggcgtttttt gtccttgcta
     4801 tttttaatgg ctctaggctc ctttgccttg gttggcttaa aggtggctgg tcccaatatg
     4861 gaaaaaactg ctagtcacta tctagaggag catcaggtta tggaccttag tatcctagcc
     4921 tcgcatggct tttctgatag agataagcaa gaattagcct ctcttaaaaa tgcaagacta
     4981 gagtatgcga gctttgttga tggtgctttt gatcaccaga ggaaggctat taggctttat
     5041 tctatgccac aaagcctatc tcaggccagc ttggtcaagg gagattaccc tagcaaggct
     5101 agcgacattt tgctatctga agctttatca agccgctatc ggcttgggca aataatcacg
     5161 ataagcctaa aaacaaaggg attgctaaag catagatcct atcgtgttgt cggctttgct
     5221 cattctccag aaatatggtc caaaacaaac ttaggtgttt cctcagcagg ggatggtaat
     5281 ctctatgcct atgcctacct tcaccctagt gcctttcagc aagggcacaa tctcttacgc
     5341 attcggtatg atgatttaag agggttgaat gccttttcaa ctcaatacaa tgaacgattg
     5401 ctacaacacc aagcagagct tgatcagatc ttgcaggaca atggtcaaga gcgttatgaa
     5461 gaaatgctca atgaccttaa tcgcagcttg aaagatagta aagttaagct cgaagagcaa
     5521 aggactgttc ttaaggcaag tgaagaccag ctggctttgc taagtggtca tgccttagag
     5581 caagcgcaga ctcagctaaa gcaagggcag gaagagttag ctaaaaaaga agcaagcttg
     5641 ctagagttag ctgaaaagca aagggcagcg atgatcaagc caacctatac tagctatagt
     5701 cgctcaacgc tgccaggtgg tgagggttat caaacctatg ccacctcaac acagtccata
     5761 tcgcatgttg gaaatatctt tcctgttgtt ttgtatttgg ttgcggcctt agttactttt
     5821 acaacaatgg ctcgctatgt tgacgaagaa cgaacgaact caggcttact aaaggcaata
     5881 ggctattctg attgggatat taccaaaaaa tttctgctat atggtgcctt agctgccttg
     5941 ttgggcactg gattaggagt tttaggaggg acttattttt tatctcggct catctcagct
     6001 atcctaacag atgcattgac tatcggctct actcagcttt atttttattg gagctatagt
     6061 gtggttgcag tgcttttagc cttgttatct gctgttttga cagcttatat ggtggtgaga
     6121 cgtgagcttt ttctcagacc ctcacaactg ttgctgccta agcctcctag tagcggggca
     6181 aggatttggc tggagcatgt ctcctttatc tggcggcgtt tatcctttac ctataaggtt
     6241 acttttcgaa atatctttcg atataagcaa agaatgctga tgacagtaat tggagtagca
     6301 ggttctgttg cgctcttatt ttccggcttg ggcattcaat cctcacttgc taatagccta
     6361 agctatcaat ttggcaagct gacagcctat gacatgctcg tggtagaagc tccaacagca
     6421 gaagctcatg ataggcagga gctggcacaa tatttgaagg cagatcagat tgctagtaag
     6481 aaagagattt attacgctaa cttatcacta aagataaaag acttagacaa caagcaaaca
     6541 gtgtcgttga tttctagcga tcagagcact ctatctccct attttagctt gattggtgct
     6601 gctgaccgaa aaaagctaga ccttccaagt actggagtgc ttatctcaaa aaagcttgct
     6661 gactattatc aggctcatgc aggagatcag cttgagcttg aagctagtaa cggtaaacgc
     6721 tatcagttaa gagtgagtca ggttattgac atgactgttg gtcattactt gttcatgtct
     6781 aaatcttatt atcagcaggt atttcgggat atggaggctt caccatccta tttggtaaca
     6841 acagcaaagg ctagtccatc tgctgtaaag gacgtagcta gtcagctctt agcaatgcct
     6901 gcggttcagg ctgtgtcaca acacagtagt attgttgcta ctgtgacagg gattgtggcg
     6961 tctttggatc aggttatgac gcttttagta cttctatcag ttctactagc cttggtcatt
     7021 ttgtatcatt tgaccaatat caatattgct gagagggtta gggaattatc aacgataaga
     7081 gtcttgggct tttatgacaa ggaggttacc ttatacattt accgggaaac catgcttttg
     7141 tctgctgttg gtattttgat cggtctctgg ggtggcagct atttgcacgc ctatatcatg
     7201 aaggtgattg ctaatgattc tatgagcttt ggtaggacag ttgatgctta tgtttaccta
     7261 gtacctgttg gggctattgt gcttttgttg attgtgcttg gctatatggt tagctaccgg
     7321 ctaagaaaga ttgatatgct agaggctcta aagtctgttg attagggtaa aatagtactt
     7381 gaaaatcgct taataatatg ctagtattaa aatactataa tttaatagaa ggatactttt
     7441 atggaagcga tgatagctgc ctatttggct gatcatagag aaaagatacc acttggtcag
     7501 gttgttgatt gctttaaggg gaaggctgtt tctcgtaagg ctgaggctgg tgaatttggt
     7561 ttgattaatc tgtctgatat gggacagcta ggaattgact atcatcaggt tagagccttt
     7621 catatggata gacgacaact attgcgctat atcttagagg atggagatgt cttgattgcc
     7681 tcaaagggga ctgttcagaa ggtttgtgtt tttcataagc aagaaaggga aatggtagcg
     7741 tcctctaata tcacagtgct gcgtcctcag agggttttgc gaggctatta tattaagttc
     7801 tttttggagt ctgctattgg tcaagccttg ttaaaggcgg cggatcatgg aaaggacgtg
     7861 attaacctat cgaccaaggc tttacttgat atccctgtac cagtgattcc tttggttaag
     7921 caggattatt tgattaatca atatttgcga ggcctgcatg actatcaacg gaaagtaaac
     7981 agagctgagc aggagtggca gtttattcaa aatgaaattc aaaaaggctt gggctagagg
     8041 taaaatgtga gcttaattga acgaacaata aaaatgctat tagcaacgat ggctgcaatc
     8101 tttcttgcct ctcagctaca gctgtcttat gccatatcag cgggaattat tgccctgtta
     8161 ggtgtgctag acactagaaa atctagctta attgttgcta gaaagcgtct gctgtctttt
     8221 ttcttagcct ttgctgtggc ggttagtcta tttgccttat ttggctttgg tctgctttcc
     8281 attggcttgt atctagcgct aaccattcct ttgctttatc agctgaaaat agaggcaggt
     8341 cttgttccta tcactgtctt ggtgactcac ctgatgtctg agcagcgtat tgatttgtca
     8401 attcttttta atgagctgtt gctgtttttg attgggacgg gtcttgccct tcttgttaac
     8461 gggtatatgg ggtctcagga gcatcgccta cgcttgtacc accaaaagat agaagatagc
     8521 ttaaaggcta tcttgtaccg ttttgaatcc tttttgttag aaggccaagg acaaaacgag
     8581 ggacagatga ttaaggaatt agagcttagc ttagatgagg cgctaaagct ggtttatcgc
     8641 gaaaggcaca ataccctctt ttatcatacc aattatcagg tgcattattt tgagatgaga
     8701 cgtcatcaaa atagattgtt ggcgcaaatg gccttaaatg tcactcagct aacatctcaa
     8761 agcagagaaa gtctcctgct ctcccatctt tttcatgaga cagctcgtca gctgagtgag
     8821 aagaattctg ctttgacatt gattgatgat attgagcaat tgcttgaggt ctttaggcaa
     8881 agagagctgc ctcagactag agaggaattt gaaagacggg cgattctgtt tcagctgttg
     8941 caggatttgg agcgctttat tctactgaag gtagaatttt atcgtgatta caaggaagag
     9001 caggcatagt agctgcttgc tgctgtgatt aagagtctgg aaaaatcatt ttctaggctt
     9061 tt
//
LOCUS       DARYXZ010000068         8705 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYXZ010000068 DARYXZ010000000
VERSION     DARYXZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8705
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            36..278
                     /locus_tag="TV186_001816"
     CDS             36..278
                     /locus_tag="TV186_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533177.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(400..1614)
                     /gene="thiI"
                     /locus_tag="TV186_001817"
     CDS             complement(400..1614)
                     /gene="thiI"
                     /locus_tag="TV186_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL1533178.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(1616..2758)
                     /locus_tag="TV186_001818"
     CDS             complement(1616..2758)
                     /locus_tag="TV186_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1533179.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKSAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            2998..3438
                     /locus_tag="TV186_001819"
     CDS             2998..3438
                     /locus_tag="TV186_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533180.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(3508..4860)
                     /gene="gorA"
                     /locus_tag="TV186_001820"
     CDS             complement(3508..4860)
                     /gene="gorA"
                     /locus_tag="TV186_001820"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL1533181.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(5054..5395)
                     /locus_tag="TV186_001821"
     CDS             complement(5054..5395)
                     /locus_tag="TV186_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL1533182.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(5456..6622)
                     /gene="aroC"
                     /locus_tag="TV186_001822"
     CDS             complement(5456..6622)
                     /gene="aroC"
                     /locus_tag="TV186_001822"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL1533183.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(6735..7415)
                     /locus_tag="TV186_001823"
     CDS             complement(6735..7415)
                     /locus_tag="TV186_001823"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL1533184.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(7412..8575)
                     /locus_tag="TV186_001824"
     CDS             complement(7412..8575)
                     /locus_tag="TV186_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL1533185.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         2558 a         2062 c         1624 g         2461 t
ORIGIN      
        1 ttcatgaaag gagggaaata tatgaaaaat ctatattgat aagttgtaca ctattagcca
       61 gtctcttatt aactggctgt cactcattgt ctttgcagct agctgaggct gttcaggaaa
      121 agcctattca agcggttacg gtagaggatt tgaccagaca tggcattgcc gaatccttga
      181 aagcctacct acagacgatg ggcttaacca atgaagaggc tatgaaacaa tacgaggagg
      241 tcctttctga tgagattatc cagtatttta gcagctaaat aagagaattt gagcaaaatc
      301 agctaaaaac aaaagccaga gcctttaata actaataggt ctggcttttt ttgactgttt
      361 agatagactg cttatgttgt agggctaggt gcgcacctcc tacaacaatt cctcaataag
      421 cgttgataag ctgtcagttt cgatttcagg agtgatctca gttactctga tccctgccac
      481 tgctcgctcg accaatccgt cgacatcaaa gcgagactca tatcgttcaa catttgctag
      541 cttgggattg gttttgggac gatcaggagc aaaaatagta cagcagtctt caaagggctg
      601 aatggaaata tcaaaggtgt caatttgctg agcgatatca atgatttcta gcttatccat
      661 tgccacaact ggtctgataa tcggagttga agtgactgca ttaatagcct gcatgctctc
      721 taaggtctgg cttgcaacct gtcctaagct ttcaccgtta ataatcacta aagcctttcg
      781 cttctcacga atagcatctg tgatccgcag catgaagcgt ctagtaagtg tcatcaaata
      841 ggcttcgggt gccttatgct tgatctcctc ttgaatctcg gtaaatggaa cctcgataaa
      901 ctgtatatta cctccaaaac gtgttaagcg ctgcgttaga tccttggctt ttcttagcgc
      961 accaggactg gtatagggtg ggcttgcaaa atgcactgcc tcaatctcaa cacctcgttt
     1021 cagggataga tagcccgcaa ccggtgaatc aataccacct gatagcatca gcattccctt
     1081 tcctgaagct ccaaccggca gccctccagc tccctttata tcttcgtgag acagataagc
     1141 agcctcatca cgaatttcga cctttagggt aacatcagga tttttcatct gtgccttgat
     1201 atgcggcaaa gcctcaaaga cggctgctcc taaggtgtgg ttgaggtcgc ggctatctag
     1261 ctcaaactga tggtcactac gcttgctgga tattttaaag gttagccctt cgcgatacaa
     1321 ggagctcata atctcctgaa ctgctgctat cagtacaggg acactttttt caactttata
     1381 gacaggagat aagccctgaa taccaaacac cggctttaag gcttcaatca cagacctatc
     1441 atctgcacca ttaagtaaaa catgggtcct gtctcgagtt gatctgactg tcacctcaga
     1501 ataggcagaa agaacatctt gaatattagc ttttagccga ttaataaacc gcatacggtt
     1561 ttttcccttg gtcgataact ccccatgacg aaccattatt tctgaatatt tcatattatc
     1621 taaccttttg tgttttttca taaatctgtt taaaaatcgt taaaaattgc tcaacctgtc
     1681 ccatatcatt atcatcatct aggctgatac ggactgctgt ttgagccaat gctgctggaa
     1741 ttcccattga gactaaggtt cctgccgact ttccaacctt tgatgagcag gcactcgttg
     1801 ttgatatata aatctcatgc ttttcaaatg cgtgcacaat aacctctcca cgaacgccct
     1861 ttataccaaa ggtcagaata tgaggagcaa aatcatctat ctcagaaaag agaatggtat
     1921 cctcataggc ctgcaaggct tgataaataa cctttttcat ggctgctatc cttgcttgag
     1981 atctatcctg tctttctgtg atgatcctta aagccttggc catacttgca atagctgcca
     2041 cgttttcagt tgtcgaacgt agctcatctt cttgaccgcc accgaccaat aagggagtga
     2101 ttcgctttcc tgatttttta taaagaaagc caacaccacg aacagcatga aatttatgac
     2161 cagaaaaaga agctaagtca acacgcgcgg ttaagtaagc ctcaacagga agcttcccaa
     2221 tagcctgaac agcatcgaca tgaaaggtaa tggtgggctt atcagccaaa agctctgata
     2281 tggctgcaat cggctgaatt gacccaatct cattgttaac cgccataatg gaaactaata
     2341 tggtatcttt tcggattaag gcagctagct ttttgacatc aacaactccc ttatctgtga
     2401 caggagcata agacagctca aagccttgac tttctagcca tttggcgctt tctctgacag
     2461 ctgggtgctc aatggctgag acaatgatgt gcttaccaaa gtgagatttt tcaaaggcaa
     2521 tccccttgat agcccaattg tcgctttccg ttccgccaga ggtaaagaaa atctctttgg
     2581 cctctacatc aagtaaggcc gctatttgcc tgcgcgaagc ctccaatata cgactggcat
     2641 tggctcctag ctgatggaga ctagagggat tgccgtaaat cttactggcc acttcctgat
     2701 acgttttaag tgcctcttcg taaggcttgg tagtggctgc attatcaaaa taaatcatgt
     2761 gtcaccttca tttttattca atactttatt gtatcacaaa tttgatgaaa tgaaaaaata
     2821 gatctttttg caggatagga caactctatc ctagacaata aggtaaaccg ttgacttgat
     2881 ttttgttcta gattatactg gtagatgata gagctaagtc tgaaatgcct gttagccatt
     2941 aaagacctaa agcatttgac tttagctagc ctatgactcg ttaaaggaga tattctcatg
     3001 tcatcacatt attcacgtca acaaaagcct aaaaaatcag caagtattcc cacaaagcat
     3061 attaaaactg gctttaccgc ccttcaaaaa accattgcct tagttggtag tgttctgagt
     3121 attgttgtag cgacaatcac tattaatcga gctctacaac catcaaatga gcaacccaaa
     3181 agcgattcct ctccgtcatc aacatcaacg attgtgaaaa ttattgaaaa ggagtcgtca
     3241 cactcaaata aggaagagac tgacaagaca gaaactaatt ctgattctag cggtactcag
     3301 gcgacacata ctactcctag ctcagctgat cctgctacta aggatacaga aaaacaacag
     3361 aataccgaaa cggaagcacc ggctgctaat caacccacag ctaatgagcc agctcctaac
     3421 agtacaagca atccataaca caaaacacga taacaggcaa ttcagataag ctctgaattg
     3481 tctgctatcg tgttttatca tgtgctgtta tctcatggta acaaactctt cagcacctgt
     3541 agggtgaatg gcaacagtat tgtcaaaatc agccttagta gcccccattt taatggcaac
     3601 agcaaagcct tgaatcatct catcaacacc ataaccaata ccatgcagac caacgatggt
     3661 ctcttcttct cctgcaacga tcaatttcat taggcagggc tggcgatgac tagtaatagc
     3721 tgtatacatg gacgtaaatt gtgattgata gacacgaaca gccgcttgcc cataggcttg
     3781 aatagctgcc tcttctgtta agccgatcga gccaattggc ggatggctaa agacaactgt
     3841 cgcaaccttg ttataatcaa gcttttcatt gggcttatta tgaaacaagc gctctgccaa
     3901 gcgacgacct gctgcgacag cgactggggt caaagcaagc tttccattaa catcaccaac
     3961 agcatagatg ccatcaacag atgtgttttc ataagcgtca acagcaatat agcccttctt
     4021 atccagctca actcctgtat gctccaagcc aaagcctgtc acatttggct tgcggccaat
     4081 tgcccaaatc acttggtcca cttcaagcct acgaccatcg gacaaatgca cttgaagaga
     4141 gccatcatta gccttggtaa ccttagtaac atcggcattg gtatgcagcc ttggtccaga
     4201 taccttcatc tcatcgacca gaacctggat aatatcctga tcaaaggtcc tcagtggcct
     4261 gtcatagcga accagcaaat ccgtctgaga acctagggca ttgagcactc ctgcaatctc
     4321 aacagcaata tagccagcac cgacaactgc tgttcgtttt ggaatatcat ctaaagcaaa
     4381 gaaaccatct gagctaatcc ccagctcagc tccttcaatg tcaggaaaaa taggctgacc
     4441 accagtagcg attaaaatat ggggggctgt ataggtctta cctgcaatgt caaccgtatg
     4501 ctgatcaata aatcgtgcat aatcataaat acgatcaacc ccgttatgct caaagccctt
     4561 ctcataagag gcatgaatac gatcaatata ggcctgacga ttgcttttta aggttttaaa
     4621 atcaaaccta tcctctaaca ccgtaaaccc gtaatccttc gcataggtat gaatcgtttc
     4681 tgctacctgt gcgccatacc acatgacctt tttaggcacg cagcccaaat taacacaggt
     4741 ccctccaata gccttgccct cagctaatag gaccttagca ccgtacattg ctgcacgatt
     4801 cgccgaggca atcccagcgc tcccaccacc aatcacaata taatcatact gaattgccat
     4861 taatttacca cctttactct taatgcttgc ctcaatagat ttgttattaa gctatcatta
     4921 ttgctttatt ttaatctact gtcatttgac tataacataa aataacttgt gtctcaaatc
     4981 cctgctacga caaaaaaaga ttgtgataag catcaacaat cctttcttct cttaatccta
     5041 agccagctta gctctacttg gccaaatcct tcaatggtgc aaatacaatc cgttcaatat
     5101 cattaacata gacggaaaga gcctgctgag cgttaaaata cccttttaat aggtcattgg
     5161 cctcaatttt ttggctgaga gcctgaatat ctgcctgctc tgtctctgtt ggcagctgac
     5221 cggtctgcat gagtccttgc aatttttctt gcacagcaac aaactcatca aatagctgac
     5281 tggcagcctc atctgcctta atctcttctc tggcttccaa ggccttgcga tactctggga
     5341 gcgcacgaac agctcgctca agcttattgg cataatcata aatatcttgg gacatctgga
     5401 tctcctttta tcatttatta tccttatcat atcacaatat caagccattt gtcgcttaaa
     5461 aatgatgaac atagtcacga taggcaaaaa aagcctgctt taaatcggtc atattgtctg
     5521 atggaaattg ttccaaaatc tcttttgtga tgacagttgc tacaacattt tccatcacga
     5581 caccggcagc cggcagagcc gtaggatcag aacgctcaac agtagccttg taaggctcgt
     5641 gcgtctcagt atccacagac attaggggct tgtagagggt gggaatcggc ttcatcaccc
     5701 ctttgacaac aataggctga ccagtagtca tacctgcctc aaagccacct agtcggtttg
     5761 ttcgacgact gtagccgctt gtctcatgcc aaatgatgtc gtccatgacc tgcgagcctt
     5821 tttggtagcc catgtcaaag cccataccaa attcgacccc tttaaaggcg ttgatagaca
     5881 ggacagcctg cgcgattttg gcgtctaatt tacgatccca ctgaacatat gaacctaagc
     5941 ctgctggtaa gccatgaatg agtgtttcaa taataccacc aagcgtatct ccttcttttt
     6001 tgacttgatc aatatgggcc ttgatagtcg cctcttgctt gggattgaca atagataaat
     6061 cagaagactc tgctactttt ttgatatctg caaaggacat cgcctcaggc acagctacct
     6121 cgataccacc aaaaactagg acatgattag cagtttcgat cccaagctca gtaaggattg
     6181 ccttagcaat tgcaccaacg gccacacgca tcgctgtttc tctggcagag gagcgctcaa
     6241 gcgcatttct taaatcatca aaacgatatt tgatcccccc aaccaagtca gcatgaccag
     6301 ggcgtggacg agtgatttta cgcttgaact tgatttgctc ttcaacagcc tcaacagcca
     6361 taatgtctag ccatttttga tggtccttgt tttgaatggt taaagtaatt ggtgctcctg
     6421 ttgttttgcc atgacgaaca cctgaagaga tatgcacacg atctgattca atgcgcatgc
     6481 gtgcgccacg accatatccc ccctgccgac gcttcagttc cttgttaata agctcagctg
     6541 ataatgctaa gcctgcagga attccctcta taatggccgt caaagcttgt ccatgtgact
     6601 cacctgctgt taaatacctc attattcctc catttatcaa tcatagacat aaaaagcaaa
     6661 cctgccctcc tctagacaac taaaagacat tattctaagc tatccaagag aataatgtct
     6721 gttaccgtat cttatcaatc ctcagattcc aaaacatgaa gaatcctttt catatcagcc
     6781 aaggaaacct gccctggtgc actggcttga tctaaggaca caaaagtcca cgaggaccct
     6841 acaacatcac ctgccaagcg tgatagtctg cctagctttc ccattgacat ggttgcaaat
     6901 tcctgctctg ggttaagtgt tttaaagcct ctggtataat tcatcaaatc caaaacgtcc
     6961 tgctcgctct gtggcatgac agcaatcttg acaacgcgag gagctagctt agtcatctcc
     7021 gaaaaagcct ccatcagatt ttcaggcgtc tcatcaaaat tgtgataaga caagacaaga
     7081 ttcggaaagt caagcatttc atgaaagaca gccttgtgac taaagtattc aaagtcaata
     7141 tagtcaggat tataaatcgc attgatctcc ttgatcaaat caacgtattc ctgatcagaa
     7201 agtgtaatat gccctccttc ttgacttgta cgaagggtaa aaataatctc tctacctgca
     7261 aatttttcaa aaatagctgg cgctacagaa acaatatcct ccttaggaag aaagtctgct
     7321 cgccactcga ttaaattaac atcttgatat ttagaaacgt cgatagattg agcctcttca
     7381 acatttcttg gcatgactgg tgctacaatt ttcattctcg tacccttata gtaaatacct
     7441 ttaaataatt acttctttca tctgctttat tgatagtaaa atcacttgga agctgctcaa
     7501 gtgtcatctg agctaatggc ctgcctccca atcctttgat aatttgcttt ttaaactggt
     7561 taacagtcat attggcagca tttgttgaag cgataattgt tcccttgggg gccaataggt
     7621 ctagagcctc agcgattaat tgatggtaat ccttactcac tgaaaacgtc tgctttttgt
     7681 ttctggcaaa gcttggtgga tcaataataa taagatcaaa agaaagttgc tttcgcttag
     7741 catacttaaa atagtcaaaa acgtccataa ccacaagctg atgactggat aggtccaact
     7801 gattttgaac aaaatgagcc tttgataact ctctggagcg ctttgccaaa tcaacagagg
     7861 ttgtctcaac tgcaccgccc attgctgcag ctacagaaaa agctgctgta tatgagaaca
     7921 ggtttaaaac agtctttcca agcgccaagc cgtccaccag acctcgtcta acctcatgct
     7981 gatcaagaaa aatccctgtc atcaagccat catttaaaaa tacctgatag gctacgccat
     8041 tttctaaaat ggtaaaggta tcaggagcaa acgcgccata caaatgagcc gtctccttat
     8101 ctggtccctt aaagcgaatc ttttcataag ctcccctgac ctcaggaaaa acctctcgaa
     8161 aagcctgaat aataagctcc ttttcttgat aaacaaagac attataccaa gaaaataaag
     8221 caaagtcctt atagaggtct atggttagtc ctccaaaatc atcaccgtct tggttaaaaa
     8281 gacggtaagc atttgtccat tcagacgcgg caaaatgctc tcttttcttc ttagctgtct
     8341 taaataaggt cacaaaataa gaaaccgaca atttcttaac agaccttcct agataccagc
     8401 ctactccctt atgttgcttt gaaaggtaag ctgtgccgat gagctgatga gatgaattca
     8461 caagctgcac taactggtag tcccaaatgg tgccatcaaa atccttttca tctagtaatt
     8521 gtatccctgc tgctatcttg cgttcaacaa ggggattaat acagacctta ttcatagttt
     8581 ctattataac aaaaactatt aaaaaatcat actagattta aacttattgc aagcattagc
     8641 tccatatttt tggtataatt taatctgaga ttttatttgg agattatatc ttttaggaaa
     8701 aaatg
//
LOCUS       DARYXZ010000069         8115 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYXZ010000069 DARYXZ010000000
VERSION     DARYXZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8115
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(2..2005)
                     /locus_tag="TV186_001825"
     CDS             complement(2..2005)
                     /locus_tag="TV186_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEL1533186.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYASWPFVKVCIILSYCGQAAWILAHKD
                     SGIALNPFFASVPEGLRVYLVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFKIT
                     YPGANLGQLYIPVINWSLFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLAYYL
                     IKEGVKPLLASLLMAFFAFIEFIFFLASAVKFMHGGYVVVVLALAIVFVMVIWHAGTM
                     IVAKYVKSLSLNDYKHQIKLLRDDLRFDLYQTNVVYLTNRMKKDLIDRSILYSILDKR
                     PKRAQVYWFVNVRVTDEPYTATYKVDMLETDYIVCVELYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQAQDYTITPGREVGDFRFVIIEERVSHARQLSTLERFVMQTKASIKHVT
                     ASPMRWFGLQYSEATVEVVPLLLSDVLKLPIKEIKACTKDEKA"
     gene            complement(2132..3748)
                     /locus_tag="TV186_001826"
     CDS             complement(2132..3748)
                     /locus_tag="TV186_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1533187.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(4164..5708)
                     /locus_tag="TV186_001827"
     CDS             complement(4164..5708)
                     /locus_tag="TV186_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL1533188.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDFEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(5877..6572)
                     /locus_tag="TV186_001828"
     CDS             complement(5877..6572)
                     /locus_tag="TV186_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL1533189.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(6656..8041)
                     /locus_tag="TV186_001829"
     CDS             complement(6656..8041)
                     /locus_tag="TV186_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL1533190.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2468 a         1932 c         1519 g         2196 t
ORIGIN      
        1 cctaggcctt ttcatctttt gtacacgctt tgatttcctt gattggaagc tttaagacat
       61 ctgataagag taaaggaaca acctcaactg ttgcctcaga atattgcagg ccaaaccaac
      121 gcatagggct tgctgtcaca tgcttgatac tagcctttgt ctgcatgaca aaacgttcca
      181 gagtactcag ctgccttgca tgcgacacgc gctcctcaat gatcacaaac ctaaagtcac
      241 caacctctcg acctggtgta atcgtgtaat cctgagcttg cttaggcaga cgaccactct
      301 ccatcaaatc ctgaacaatc gttctaaggt aacgtggaac agtctgtggc attctaaagc
      361 caaggtagag ctctacacaa acgatatagt ctgtttctaa catatccacc ttgtaggtcg
      421 ccgtataagg ctcatctgtc acacgaacat taacaaacca ataaacctgt gcgcgcttag
      481 gacgcttatc taaaatagaa tacaggattg agcgatcaat cagatctttt ttcatgcgat
      541 tggtcaagta aacaacattg gtctgataca aatcaaagcg aagatcatct ctgaggagct
      601 tgatttgatg cttgtaatca tttaggctca aggacttaac atatttagca acaatcatgg
      661 ttccagcatg ccaaatcacc ataacaaaga caatggcaag agctaaaaca acaacaacat
      721 agcccccatg cataaactta actgcagacg ctaaaaagaa aataaactca ataaaggcaa
      781 aaaaagccat gagcagacta gccaggagcg gctttacccc ctccttaata aggtaatagg
      841 ctaagagaat cgttgtcatc agcatggtaa tcgtgatggc aaggccatag gcagcctcca
      901 tatgcgctga tgttctaaaa tacagcaccg tacaagacgt taccgcaaac aagctccagt
      961 taatgacagg gatgtatagt tggcctaggt tggcacctgg ataggtaatc ttaaacaacg
     1021 gaaaaatctt caagcgcata gcctcagaaa ccaaggtaaa ggaacctgag attaaagcct
     1081 gcgaagcaat aatggctgct agagttgcta gaataacaag ataaacccgt aatccctctg
     1141 gaacactagc aaagaaggga ttaagcgcaa tgcctgagtc cttatgcgct aaaatccaag
     1201 ctgcctgacc acaataggat aagatgatac aaaccttaac aaagggccag ctagcataaa
     1261 tatttcctcg accgacatga cctaaatcag aataaagagc ttcagcacca gttgtcgcta
     1321 aaaaaataga gcctaaaatg aaaatacccc gatgattttc cggactaacc aataagtgca
     1381 gcgcataata gggattgata gcctttagga tttccaaatg ctgtaagcta ttcaagagac
     1441 cactgatccc caaaacgcta aaccaaacca gcatgactgg cccaaataat ttaccaataa
     1501 cacccgttcc aaagcgctgc aggccaaaca agaccatcaa tatcagcaag gtcgttagga
     1561 tcacattggt ctgattctgg taaatactgc tgagctcagg aacagccttt aagccttcaa
     1621 tggctgatgt gaccgtaaca gctggtgtca aggcaccatc tgataagagc gttgctcccc
     1681 caagcatagc tggaatgatt aaccaccttg acatccttct aactaaggta aagagtgaaa
     1741 aaatccctcc ctcatgatga ttatcagcct ttaaagcaat caaaacatac ttgattgtcg
     1801 ttaccaaggt tagagtccaa ataatcaagg atactgagcc taaaataaaa gcttcagaca
     1861 cctgtgaaag gccgccttga ttgtcaacca acgactgcat ggtatacagt ggacttgtgc
     1921 caatatcacc atagacaatt cctagtgcaa taataaaacc tgcctttgtt gctttatcaa
     1981 aggcatcatg atgggcatta gacatcccaa tgttcctcct aagacttaat catgccaaat
     2041 ggactgagac cattatagca aaatctataa caaaatcaat attttcagaa aattaaaaag
     2101 agagctgaca atcatcagct ctcttgaaac tttagttccc tttatgacgg ataataaatc
     2161 cagacgtctt agcttcgaca gccttgccct tcttgtgcag gtccttgtta gagcgttttt
     2221 gctttcgctt aaagtcatag ctaccactgc tatcatgact gtcacgttta tcacgccttg
     2281 gacggcggtc accatcataa acatttcttt tctcatgacg atagccacct cgacggttat
     2341 cacgaccgct acgactacga ttgccacgac ctgtcttgcc atttttattg ccatgaccac
     2401 caccaacata cttaaacggt aatggctttt cacgcgctat ctcaacctct ggtaaggtat
     2461 ctggatcttg gacggtcaag ctaaggatat agagcgctag ctcctctggg gtaaactctg
     2521 ctgccaattt catcgcatcg cccttaaatt tctcaaagtt tgagcgaata gcatcatctg
     2581 caaaatcacg ctcaattttt ttgagggcaa cctttttctt agcctgaaag gcttcctctg
     2641 ccgtagctgg cttgagtggc ttcatgcgct tcttagtcag gtgctcaatc atggtcagat
     2701 agcccatctc atttggtgag acaaaggtaa tggattcccc tgacttacct gcacgaccgg
     2761 tccggccaat acggtgcaca tagctttctg gatcctgtgt aatatcgtaa ttgtacacat
     2821 gagtaacgcc tgaaatatca agcccacgcg cagcaacatc ggttgccact aaaatatcaa
     2881 gttgatcatt tttaaagtcg cgtatgacac gaaggcgctt attttggtca aggtcaccat
     2941 gtatcccttc tgcgcgaaaa ccacgcaatt ttaagccgcg cgtgatttca tcaacacgac
     3001 gctttgtgcg accaaataca attgatagct ctggctgctg aacgtccatc agacgtgtca
     3061 tggtatcaaa tttttcttgc tccttaacac gcacatagta ttgatcaaca ttcacatttg
     3121 ttaattcctt gtttttaacc tgaacatgct caggatcctt cataaacttg acaccaattt
     3181 ccttgattgg agctggcatt gttgctgaaa ataacagggt ttgacgatcg tcagggacac
     3241 gactaataat cgcttcaatg tcctctaaaa atcccatatt caagcattca tcagcttcat
     3301 ctaaaatgag tgtctcaaca tggtctagcc tcaaggcctt acgcttaatc aaatctaaca
     3361 gacgtcctgg cgttccaaca acgacatgcg ccccagactt tagggcctta atttgcttct
     3421 caatgcttga gccaccatat actgagcgaa ccttgacgcc tttatcacga ccaaaacgga
     3481 acagctcttc ctgactttgg acagccagct cacgcgtcgg agcaatcacc aatgcctgaa
     3541 tggtgttatc ggctgtacga atcttattca gagttggtag accaaaggct gctgtttttc
     3601 ctgttcctgt ctgagcctgt ccgataacat ctcgtccctc caaggctaac ggaatggtca
     3661 gctcctgaat aggagaggct ttttcaaagc ctgctgtaac aacagctgac tgaatatctt
     3721 ctgataagtt aaatgctgta aatttcaatt gtttctcttt tctaaaaagg cagtgcgaag
     3781 ctgccttata aaccttttaa tattgtcgtt cgattaacaa cctatttagt gtaacataat
     3841 taatattaaa aagataggaa ataagccatg aaagtgtttt tatctcaaaa tgattaacac
     3901 tatcaggcag ctaaattgat aaaagcgtca ctccttattg ctgattggct aacagcctca
     3961 aaaaggcctc gtcggacttg cttacctatg ctttttatct actctgctaa aaagactcgg
     4021 cacagagacg agccttcgcg attccatcac caatcttcaa agacagcaat taggattcct
     4081 gaaagctcct tatgccaata gcctgccttt tcttagcagc agaagtgcaa aaacggacta
     4141 ggttccccta atccgcttag ctgctacatt tttgcttcta gcttaacatc tgggtattta
     4201 tctgcaaacc aacgaagcgc aaagtcattt tcaaagagaa aaacaggctg atcaaagcga
     4261 tcccttgcca aaatgtttcg gcttgaggac atgcgttggt ccaaatcctc ctctgagatc
     4321 caacgaacag tctttttgcc cattggtgtc atgatgacct ctgcattgta ctcaccctcc
     4381 atacggtgct tgaaaacctc aaactgcagc tgaccaactg cgcccagcat gtattcacct
     4441 gtctgataat tcttataaag ctgaacagcc ccctcctgta caagctgctc aatacctttg
     4501 tggaaagatt tttgcttcat gacattctta ggtgcaacct tcataaaaat ctctggggta
     4561 aaggtcggca atggctcaaa ttcaaacagg tttttactaa cgctcaaggt atctccaacc
     4621 tgataagtcc ctgtatcgta gaccccaata atatcaccgg caactgcatt ttggacattt
     4681 tcacgagact cagccataaa ctgagtaaca tttgatagct taacgctttt acctgtacga
     4741 gacagcttta cagccattcc cttttgaaac tctccagaga caatacgcac aaaggcaatg
     4801 cggtcacgat gcttagggtc catgttagcc tgaatcttaa agacaaagcc tgaaaaatcc
     4861 tgattgaggg gatcaatcat ctggtccgtt gtcgtcttat gcccatgagg ctctggtgca
     4921 aaggctaaaa aggtatctaa aaaggtttgt accccaaaat ttgttaaggc agagccaaag
     4981 aataccggag tcagctgacc atctaaaata gcctgctctg aaaagtcatt acctgcctcc
     5041 tccaagagct caatatcttc aagcacctgc tcataaaaag ggttgctggc aaaaatcctt
     5101 gccccctcct ctaaatcagc aaacctctgc tcccccttat aaagctccaa gcgtttgttg
     5161 tgcaaatcat acagaccttc aaaggctcgt cccataccaa ttggccagtt catggggtaa
     5221 gaagcaatcc caagaacctc ttctagctcc tccaacaact ccaaaggctc acgtccatca
     5281 cgatctaatt tattaataaa cgtaaaaaca ggtatgttac gatgcttaac aacctcaaag
     5341 agctttttcg tctgtgcttc gatcccttta gccgaatcaa caaccatcac agcagcatca
     5401 actgccatta aggtacgata agtatcctct gaaaagtcct cgtgaccagg tgtatctaaa
     5461 atattgatac gcttaccagc ataatcaaac tgcatgactg atgatgtgac tgaaatccca
     5521 cgttgctttt caaaatccat ccaatctgac ttagcaaatt gaccagattt ttttccttta
     5581 acggtcccag cctcacgaat ctcaccacca aaataaagta actgttctgt aatagttgtt
     5641 ttaccagcat ctgggtgact gataatcgca aaggttcgac gctttttaat ttcttctgta
     5701 attgacattc ttttttcctt atttgttcac attgcagagc aagactctga ttaatagctt
     5761 caagtcacac gtcacagtta tgtctacatg atctcactcc taaatactga tatgataaaa
     5821 agagctgcta gagcagctcc tttattatag ctgattcgaa gcgctttttc aacgccctat
     5881 ctttctttag agagcttcag ctctaactga ttggcctcac taaatctcac atagataagt
     5941 tcaatcagct taattaaacc agtcaacccc attgtcacaa tgacaaaatt cataagcagg
     6001 tgatgcgtat gaataatcgg aatatccatc acaaagccgt aatttccctt tgttgccaaa
     6061 ttgatcaata ctaaaacaaa attaatggtt gccaagtaac ggcaaacaag gactggcttt
     6121 agctgacttg gattgtaaaa ccgcagcagg taaaccaagc cattgaccaa aagagcataa
     6181 tgccccaggt aaaaagaaat attagccaca tgccatagct gataagggta taaatcaggt
     6241 gataacaggg ccaaaaaggt cccaccaatc cctaaaacca taaaaagctg ctttaagcta
     6301 ctgcgatccg gtaagaaaaa gatagctagc atggccattc ggcaatggta aagcggcaaa
     6361 gcctctgtca acggaaagcc tcgcaaggca taccagctat acaaaccaac caattggacc
     6421 aactgaagcc ctaagaagat atagcgatac gactttagct gatagagctg cagggtcata
     6481 aaaaccaaaa acggcgctat catcaccgac aatagataaa atagcaagga cacatgcggt
     6541 agcccaatag gttcaattgc aaaaaaattc ataaacatcc ctttctacat tttttcatta
     6601 taccttaatc ttaatgagag gacaagatgt ttcatgtgtt ttttctgaaa aagtgttagg
     6661 aggacttccc agcatgagga gctgtcaggc gatcaaccac atttgctagc agcatggagt
     6721 ggctgccctt tagcagcatc tggtcattag gctcaagaat agtcaacagg tactggcaca
     6781 tgtcctcgta ttgatcctct cgattattct ttttaaagaa gctaactctg ccacttggat
     6841 aatcttgact agctagcttg gccaaggctt gaatatcatc accgtaaaag accaattgat
     6901 caatacgctt gggatctaag ctggtaatca gctgagaatg caaagcaact gagtcagcac
     6961 ctaattcctt catatcagct aaaacagcta tttttttgcc attagggttg gccggaatgg
     7021 cagcaaaggt ttccaaaatt aaccgcatag cagttggatt ggcattgtac acatctgcca
     7081 aaaggtcggc gccattagcc gccttgaccc actcggttcg gtggcgtgtc agcttgacgg
     7141 tttctaaagc ttctataata tcctcatcag gcacagccaa gagtttacca acataagctg
     7201 ctatcatagc attggttgca ttgtattttc cagttaaggg aagagtgacc ggtcttggta
     7261 agacattagt cctaaaggtc aaggagtcct tgcactcttt gatatcctca accaccagct
     7321 cttgatgatc gccaaagcga atgaccatct gactatccgg caaatatgga tcaaggatag
     7381 gatcaccagg agcaattaaa atcccgttag agtccatccc atcaacgatt tgcattttcc
     7441 cttcggcaat cttctcgcga gagccaaagt aggctaagtg agcctcacca ataagggtta
     7501 gcaatgcaat atgaggtctg gcaattctag agagcagctg aatgtctccc atatgatcct
     7561 gccccatctc taaaacaatc ttctcagtat cctctggcat gtgaagcacc gtataaggca
     7621 agccaatgtc attattataa ttgccctggg ttttgtaggt cttataagct tttgccagga
     7681 ccgcttcaat catatccttg gttgatgttt taccgtttga gcctgttaca gcaatgacat
     7741 cgacacgtag cttatcaata taatactggg ctaatttttg aaaggcagcc aagcaattct
     7801 caactagtat atagggtctg ccactgattg ctctttctga aaaggtagct acggccccat
     7861 tttcaaaggc taagtcaata aaatcatggc catctcgctc accctgtagc ggtaaaaaaa
     7921 gatcaccttt tgtgatgttt ctactgtcaa attcaatctg attcagagga acgtcgtcta
     7981 aatcagaaag actattttga gcatcaacaa ctcttgccac ttcatgtaat gttaatttca
     8041 tcttattttt cctcttaaaa cactggtttt taaagctttg cttatattat agcataacat
     8101 attaggaata ttctt
//
LOCUS       DARYXZ010000070         7527 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYXZ010000070 DARYXZ010000000
VERSION     DARYXZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7527
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(209..424)
                     /locus_tag="TV186_001830"
     CDS             complement(209..424)
                     /locus_tag="TV186_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533191.1"
                     /translation="MVDKYIPGRYIQREIDEIIELVRDRSKFEPVRVREVQEHIQKIL
                     IQHEAEILARLEENQDQKASENSNDIF"
     gene            613..903
                     /locus_tag="TV186_001831"
     CDS             613..903
                     /locus_tag="TV186_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533192.1"
                     /translation="MAIEVFGPDFRKELLADLISLNREALKIAQFENSKSIEWVTMKR
                     LEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGA"
     gene            905..1099
                     /locus_tag="TV186_001832"
     CDS             905..1099
                     /locus_tag="TV186_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533193.1"
                     /translation="MNKLELFLLAATVILAIIARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKRWSEKRSRGEVEKCLL"
     gene            1234..1413
                     /locus_tag="TV186_001833"
     CDS             1234..1413
                     /locus_tag="TV186_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533194.1"
                     /translation="MTTTKKLGRPTSNPKSHSKRLRMTDEEVQKLEYCTKQTGKTQTD
                     VLMLGLDKVYQELKK"
     gene            1586..1858
                     /locus_tag="TV186_001834"
     CDS             1586..1858
                     /locus_tag="TV186_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533195.1"
                     /translation="MDNSKLANHQKVTVVCTDFNVYLNGIRLTGARPETAKLAERCGE
                     KLITLSLVVTDFDDHRTPKMADMAKEAEMANKTLDWEKKHFYKSNK"
     gene            complement(1848..2228)
                     /locus_tag="TV186_001835"
     CDS             complement(1848..2228)
                     /locus_tag="TV186_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533196.1"
                     /translation="MIDYYSLYKNSLEAIGYHKLDTGVDLLQYLIATEEGKRIYSQYP
                     YREVEEIIFYTLDCLIQQDLVTATEMPRLDRRIYTIDGLTPKGMYFLGYIGQVETEVI
                     EWLNEFGVSQNPESIYNALRYIIY"
     gene            2284..2727
                     /locus_tag="TV186_001836"
     CDS             2284..2727
                     /locus_tag="TV186_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533197.1"
                     /translation="MAKTYTLTEEELNELVAERMKQAKEKRTPQGLFKDVSFDDELIP
                     INEKYPKVLKKLNRERAYKPEKHVFNQTPKVFGVDNDISYSKITTHDVHNHIRLLVLN
                     VFGKSQNKEVLPEEYDQAIELYKELKEWFVSSYDKRLEGLVLEDD"
     gene            2844..3656
                     /locus_tag="TV186_001837"
     CDS             2844..3656
                     /locus_tag="TV186_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1533198.1"
                     /translation="MGKEKTKIYFWLKFDKKFFENIFIKRLKKMAGGDTMTVLYIRLM
                     LESLETDCILYYEGYFENLVEELAIKLEVSEDDINMTLAYFTKCGLIQIDGSGNAQMP
                     QAKAMLESETNWAKYKRETRKIGQIPTNVQPMSNQCPTEIEIEKDKKKDINIDIKSEV
                     EEEIKEISTADENSLKIISDYFQQEIGILSPNQFEQLSDYITITKMEVDVVKSAITRA
                     ADNSKRSFGYVNSILRNWRQNGITTMVKVKEESRNFKARKAKQEEVSEYDTW"
     gene            3643..4425
                     /locus_tag="TV186_001838"
     CDS             3643..4425
                     /locus_tag="TV186_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1533199.1"
                     /translation="MTLGDNNALAKIAVAYQKNVKKESTVCQKHGCIYITILKTGLTV
                     CPMCHKEDLESQNELHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRVITPKQ
                     QEVLSWAKSMANYWYTGGKGNIIMTGKAGRGKSHLAYSIIRGLSDETKKLGLLVNITD
                     LLSEIKRDFSQEAFWLDKLKNVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTN
                     LTPVEIRKNYGERIASRIRKGCAKSHIMDFAGLEDERIKLWN"
     gene            4562..4768
                     /locus_tag="TV186_001839"
     CDS             4562..4768
                     /locus_tag="TV186_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533200.1"
                     /translation="MTPEEAEKAKIRAKQEIEVFSIYLEQAIDTFGSMLSPQEVFLAA
                     GFAYLGAGQTDIHAAVEGLYEQVR"
     gene            4930..5856
                     /locus_tag="TV186_001840"
     CDS             4930..5856
                     /locus_tag="TV186_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEL1533201.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SKSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIDEDNQDST
                     ISIPKDITPPETNSLDDLIGHQNEKKDAPGNLKDVTDDLHSEPEKTLTDENKTVLEDT
                     SYPADEIPDFDQETGEIKASEGNLFDNLGDLI"
     gene            5853..6053
                     /locus_tag="TV186_001841"
     CDS             5853..6053
                     /locus_tag="TV186_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533202.1"
                     /translation="MIKLVKIEGYYINPEYVVGVWERSALNFDDLDEKVVVIQFVGDR
                     EREECVFYDTPIDEVIKRLLDD"
     gene            6046..6843
                     /locus_tag="TV186_001842"
     CDS             6046..6843
                     /locus_tag="TV186_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1533203.1"
                     /translation="MTSLDLLGKDYYSKESAIRYWSISQYKRFRECEARALAELRGDW
                     TDTRDNTALLVGNYVHSYFEGEEAHEEFKVQNSSEMISTRGTTKGQLKKDYLVAEQMI
                     DALKSDNNFMAIYQGEKEVAITGFLGEVEFKGKIDCLNAERGYFVDIKTTKGPIDDKI
                     WNGQERVYWFEAYSYILQMAAYKNMLEAKHKKPFEPIIYAVTKETPPDTRAIRIQNLD
                     AMQNELDNLAQNIKRLDDVKKGIEKSKPCGHCEYCRANQLTQRVMIF"
     gene            7022..7363
                     /locus_tag="TV186_001843"
     CDS             7022..7363
                     /locus_tag="TV186_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533204.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGGLTMQWDFISDFKKIDDE
                     PSLDEDGELFEVAYDLVLEAKPKTKINLTSSYFAKEHKKDTDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
BASE COUNT         2773 a         1244 c         1521 g         1989 t
ORIGIN      
        1 gggcagcagt attttatcaa caaatttctt aaccaggaat atctgccagt ttagaaagga
       61 aaccacatga gaccaaaacg atatccgtat acaccaaaaa gaccctttcc gagtcaagaa
      121 agagtcgcaa gttatagatt ggctattgaa gagttaaatt ctttagcacc aacagcatcc
      181 gaaacactaa agaaaaaaat agaagaagct aaaaaatatc atttgagttt tctgaagcct
      241 tttgatcttg attttcttct aaacgagcaa gaatctcagc ttcatgttga ataagaattt
      301 tttgaatatg ttcctggact tcacgaactc taactggttc gaacttactt ctatcacgaa
      361 ccaattcaat aatttcgtcg atttctcttt gaatataacg accaggaata tatttatcaa
      421 ccatgtaatt tatcctcctt tatagcatat ttgactaacg acttcataag gaatagatgg
      481 tttgtcataa atcaattata gcagaaagag ggggcataga agaatttata tacaacaaaa
      541 aagtccgacg ggaatcggac tcaaaacaaa aactatttac ttagattata acacaagaga
      601 gaggaaggtt ccatggcaat tgaggtattt ggaccagatt tcagaaagga actacttgca
      661 gacttgattt ctctaaacag agaagcgcta aaaattgctc aattcgagaa ctctaagtca
      721 attgagtggg ttaccatgaa gcggttggaa aaagaaactg gatgggggcg aactaaattg
      781 acccagtgga gagaacaagg gaaatttaac tttaaaaggt catcagaaaa cgggaaagta
      841 ctatatgacc tagcagatgt taatagattt ttgcgaacaa gtggatatga aaaaggagca
      901 taacatgaac aaactagaat tatttttatt agcagcaacc gtcatcttag caatcattgc
      961 aagaattcag tatgaagtca taaaaaaaca taattcgccc gaaaataagc gaaaaatttt
     1021 tagggaagta gctttagaaa acagcaaaag atggagcgag aagcgctcta gaggagaggt
     1081 agaaaaatgc cttttgtaaa acggtagaaa ccacatagtc ctttgacaac tgaatagggt
     1141 accttgaaaa aatattaaaa aagtttgatt ttggggttga cttatgtatc cacataatga
     1201 tattatatat ttgtggatac gaaaggagga aatatgacca ctaccaaaaa acttggtcgt
     1261 ccaacttcta atcctaagtc tcatagcaaa agactgagaa tgacagacga agaagtacaa
     1321 aaattagaat attgtactaa acaaactgga aaaactcaga cagatgtttt gatgctaggc
     1381 ttagataagg tctatcaaga gctaaaaaaa tagcgtataa tccgccatcg ccaaactttg
     1441 gattacacgc tatcgaccga cctgaaaaca ggtacacaaa tatattatca tgtgtaccct
     1501 tttcagtcaa cctgacaagg gtattttttg cgcccttgtt gtttagataa gggtttttat
     1561 tgtacccaaa aataggagga acacaatgga taattcaaaa ctagcaaatc atcaaaaagt
     1621 aacggtagtc tgtacagatt ttaatgtcta tttgaatgga atacgactta ctggagctag
     1681 accagaaacc gctaaattag ctgagagatg cggagagaaa ctcattacac taagtctagt
     1741 agttacagat tttgatgacc atagaacacc taagatggcg gatatggcaa aggaggctga
     1801 gatggctaat aaaacattgg actgggagaa aaagcatttc tataaatcta ataaataatg
     1861 tatctcagag cgttatagat tgattctgga ttttgcgaaa ctccaaattc attaagccat
     1921 tcgataacct cggtttctac ctgcccgata tatccaagaa aatacatgcc ttttggtgtc
     1981 agaccgtcaa ttgtatatat tcgtctatct aatctcggca tttctgtggc agtaactaaa
     2041 tcttgttgga tcaaacaatc tagggtgtaa aaaataattt cttcaacttc tcgataaggg
     2101 tattgagaat atatcctttt tccttcttct gttgcaataa ggtattgaag taaatctaca
     2161 cccgtatcca acttatgata tccgatggct tcaagtgaat ttttgtataa agaatagtaa
     2221 tcaatcatac acttctccaa gtattttatt ttaaatataa caaaatagta agaggaaaac
     2281 aatatggcta aaacttacac attaaccgaa gaagaattga atgaattagt agctgagcgc
     2341 atgaaacaag cgaaagaaaa acgcacacca caaggactat tcaaagatgt cagctttgat
     2401 gatgagttga ttccaatcaa tgaaaaatat ccaaaagtac tcaagaaatt aaatcgtgaa
     2461 cgtgcttata aaccagaaaa acacgtcttc aatcagacac caaaagtttt tggtgtggac
     2521 aacgatatta gttatagcaa aattacaaca catgacgtac acaaccatat tcgtttgctt
     2581 gtcctaaatg tctttggtaa aagtcaaaat aaggaagtat tgcccgagga atatgaccaa
     2641 gcaatagagc tttacaagga attgaaagaa tggtttgtgt ctagctatga taagcgatta
     2701 gagggattgg tgctagaaga tgattaaaaa attctgcgtt aactacttac taagacagat
     2761 taacaaaagc aaactagaaa caagagataa agcgaagtta aaccacttta tcacactagt
     2821 ggactacaag ttaggaggat aaattgggta aagaaaaaac taaaatatac ttttggctaa
     2881 agttcgacaa gaagtttttt gaaaatattt ttatcaaacg tttaaaaaag atggctggcg
     2941 gagacactat gacagtcttg tatattcgtt tgatgctaga aagtttagaa acagactgca
     3001 ttttatatta cgaaggatac tttgaaaatt tggtagaaga gcttgccatc aagttagagg
     3061 tgtctgaaga cgatatcaat atgacattag cttacttcac aaaatgtggt ctaatccaga
     3121 tagacggtag cggtaacgca caaatgcccc aagctaaagc tatgctggaa agtgagacga
     3181 actgggcaaa atataaacga gaaactagaa aaattggaca aattccaacc aatgtccaac
     3241 caatgtccaa ccaatgtcca acagagatag agatagagaa agataaaaag aaagatataa
     3301 atatagatat aaagtcagaa gtagaagaag agataaaaga gatttctact gctgacgaaa
     3361 acagtctcaa aattatatct gattatttcc aacaagaaat cggtattttg tctccaaatc
     3421 agtttgagca gctgtcagac tatattacca ttacaaaaat ggaggtagat gttgttaagt
     3481 ctgctattac aagagctgct gacaattcta aacgttcttt tggttatgtt aactctatac
     3541 tgcgcaattg gcgacaaaat ggaatcacca caatggtaaa agtgaaagaa gaaagtagga
     3601 attttaaagc cagaaaagct aagcaagaag aggtctcaga atatgacact tggtgacaac
     3661 aacgcacttg ctaaaatcgc tgtagcttat caaaaaaatg tcaaaaaaga aagcactgtt
     3721 tgtcaaaaac atggttgcat ctatatcaca atccttaaaa ctggattgac agtatgtccg
     3781 atgtgtcaca aagaggactt agaaagccaa aatgagttac acgtccaaaa gcaatatgag
     3841 agagagcttg aaaacaagcg actgtactat ctcaaaaaat tatcaattat ggacgacgag
     3901 ttggaaaatg cctcatttga taatttcagg gtgatcacac ctaagcagca agaggtcctt
     3961 tcgtgggcaa aatccatggc taattactgg tatacaggag gcaaaggcaa tatcatcatg
     4021 actggtaaag ctggccgcgg gaaaagccat ctagcataca gcatcatcag aggtttgtct
     4081 gacgagacta aaaagttagg gctgcttgta aacattactg acttgctatc agagataaag
     4141 cgagacttta gccaagaggc attttggcta gataagctaa aaaatgttga ttatttggtt
     4201 ttagatgact taggcgccga aaaggtcagc gactggtcca caagtattat ttacagctta
     4261 ctaaataagc gtacaaatac aatcattact acaaacttaa cacctgttga aataaggaaa
     4321 aattatggag aacgtatcgc atcaagaatt agaaaaggct gcgctaagag ccatattatg
     4381 gattttgcag gactggaaga tgagaggatc aagctatgga actaatatta ataacttttt
     4441 ttggcctatc tgaagaacat gcagccaaaa tcatggcgct agacgaagat agccgaataa
     4501 ataaaatcga ggaattgaga gcatggagag aatgctcaaa aataacattt taggaggaaa
     4561 tatgacacca gaagaagcag aaaaagcaaa aatcagagct aaacaagaaa ttgaagtttt
     4621 tagcatatac cttgaacagg cgattgatac ttttggcagc atgctaagcc cacaagaagt
     4681 cttcttggca gcagggtttg cctaccttgg cgctggtcaa acagacatac atgcggccgt
     4741 cgaggggttg tatgagcaag ttcgatgact ttaaatttag cgaagactgg gagagtaact
     4801 actttgaggt ccaagctttg ctaggacaag agatagacaa gctacaaaat agagttgtcc
     4861 agttagcaaa cgaaaataat agattaaagg ccgaaaattg gcagttaaga cacagaaaga
     4921 ggaaatgaaa tggcgaatca attatcaaca tacacacaca aacaattttt taatgcacca
     4981 acaattcaaa aggcttttga tgacgtttgg aaaggcgccg ggacacagtt cgcagtaagc
     5041 atcttgtcag tactacaagg tagtaaaagt ttgaaatcgg catctaatga atctatttat
     5101 gcagcagcta tgaaagcagc cgtgttaaat ctgcctattg agccaagctt aggaagggcc
     5161 tatttagttc cgtacaaagg tcaagcacaa ttccaattag gctataaagg gttgattgag
     5221 ttagcgcagc gcagcggaca atacaaaaat attaatgcag gtatcgtcta taaatcacaa
     5281 ttaatttctt acaacccttt gtttgaggaa ttgatccttg actttagtaa gccacaagat
     5341 gaaattgtag ggtattttgc cgcttttaaa cttttaaatg gattcgagaa agtttctttt
     5401 tggacagtag aaaaagtaac tgcacatgga aagaaatttt caaaatcgtt tgctagcggc
     5461 ccttggaaaa cagactttga tgcaatggct caaaaaacta ttttaaaaga tattttgagt
     5521 aaatatggtc cgttatcagt tgagatgcag aaagctatcg atgaagacaa tcaagattca
     5581 acaatttcta ttccgaaaga cattacacca ccagaaacaa acagccttga cgacctaatt
     5641 ggtcaccaga acgaaaaaaa ggacgctcct ggcaatttaa aagacgtaac tgatgattta
     5701 cattccgagc cagaaaaaac gctcacagac gaaaataaga cggttttaga agacacctct
     5761 tatccagctg atgaaatccc tgattttgac caagaaacag gcgaaattaa agctagcgaa
     5821 ggcaacctct ttgataatct tggagactta atatgattaa acttgtaaaa attgaaggat
     5881 attatattaa tccagaatat gttgttggcg tttgggaaag atctgcttta aattttgacg
     5941 atttagatga aaaagtagtg gttattcaat tcgttggaga tagggaaagg gaagagtgtg
     6001 tcttttacga tacacctatt gatgaagtaa ttaagaggtt gctagatgac tagtttagac
     6061 ttacttggaa aggactatta tagcaaggaa tcagctataa gatactggtc cattagtcag
     6121 tacaagcgct ttagagaatg cgaggcaagg gcacttgctg aattacgagg ggattggaca
     6181 gataccagag ataacactgc gttgctcgtc gggaattacg tccactctta ctttgagggt
     6241 gaggaggctc acgaagaatt taaagtccaa aacagttctg aaatgatttc gaccagagga
     6301 acgacaaaag gccaattaaa aaaggattac ttagtcgctg agcagatgat tgacgctctt
     6361 aaaagcgata acaacttcat ggcaatctac caaggagaaa aggaagttgc catcacagga
     6421 tttcttggtg aggttgagtt taaaggtaag attgactgtc tgaatgctga acgtggctat
     6481 tttgtagaca ttaaaacaac aaaaggacct attgatgaca aaatttggaa tggtcaagag
     6541 cgagtttact ggtttgaggc ttacagctat attttgcaga tggctgccta caaaaacatg
     6601 ctagaggcaa aacacaaaaa gccgtttgag cctatcattt acgcagtaac aaaggaaaca
     6661 ccgccagata ccagagcaat caggattcaa aatttagatg ctatgcaaaa tgagttagac
     6721 aacctagctc aaaacatcaa gcgtttagat gatgttaaaa aaggcataga aaaatctaag
     6781 ccttgtggtc attgcgagta ttgcagggca aatcaattaa cacaaagggt aatgattttt
     6841 taactaacta ttgcaaagtg aagctcggcc tttgcaataa tcatattttc cgagcgagaa
     6901 aggaaaattg caatatcgtc aagttaacag tattgatgat ataaagagtt gctacactcg
     6961 tccttgccaa tgctcacaca caattttagg gcgagtgtgg attttaaaaa aggtgaaaaa
     7021 tatggaacaa attaaaatta caggaacagg aacagcacta attttagata gagtaaaccg
     7081 aatctttgcc atctctggcg gtttgactat gcaatgggat tttattagtg attttaaaaa
     7141 gattgacgac gaaccgtcac ttgatgaaga tggagaacta ttcgaagtag cttacgacct
     7201 tgtgcttgaa gctaaaccca aaactaaaat caatctaaca tcatcatatt ttgctaaaga
     7261 gcataagaaa gacacagacg aaattataaa agtattctcg tttatcgaag ataataagag
     7321 aaatatcttt gaaacccttg gcattcgtgg ggtgcttgaa tgagcaatct agtattatcg
     7381 ctagacatct caacttctgg tacaggttgg gccttattta aaggctcaga ccttatccag
     7441 agtggtgtct taaaacataa gagcgactct tatttcgaac gtggacgata tatggctagc
     7501 caattaagag ctatccagtc acgagca
//
LOCUS       DARYXZ010000071         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYXZ010000071 DARYXZ010000000
VERSION     DARYXZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            436..975
                     /locus_tag="TV186_001844"
     CDS             436..975
                     /locus_tag="TV186_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533205.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TV186_001845"
     CDS             972..2087
                     /locus_tag="TV186_001845"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL1533206.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGKYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TV186_001846"
     CDS             2077..3339
                     /locus_tag="TV186_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1533207.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TV186_001847"
     CDS             3385..4404
                     /locus_tag="TV186_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1533208.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TV186_001848"
     CDS             4603..5313
                     /locus_tag="TV186_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1533209.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TV186_001849"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TV186_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL1533210.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TV186_001850"
     CDS             6662..7471
                     /locus_tag="TV186_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1533211.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2020 a         1599 c         1798 g         2078 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaaag tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt acaggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYXZ010000072         7243 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYXZ010000072 DARYXZ010000000
VERSION     DARYXZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7243
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            26..628
                     /locus_tag="TV186_001851"
     CDS             26..628
                     /locus_tag="TV186_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533212.1"
                     /translation="MISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNT
                     DDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETL
                     FRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLG
                     KMIAEIPVDYMLNLLSPGYHIARYIDSIDTVPNNNRINLW"
     gene            complement(1044..1424)
                     /locus_tag="TV186_001852"
     CDS             complement(1044..1424)
                     /locus_tag="TV186_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL1533213.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(1458..2450)
                     /locus_tag="TV186_001853"
     CDS             complement(1458..2450)
                     /locus_tag="TV186_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL1533214.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(2466..3011)
                     /gene="srlA"
                     /locus_tag="TV186_001854"
     CDS             complement(2466..3011)
                     /gene="srlA"
                     /locus_tag="TV186_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL1533215.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(3147..3608)
                     /locus_tag="TV186_001855"
     CDS             complement(3147..3608)
                     /locus_tag="TV186_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL1533216.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(3608..5380)
                     /locus_tag="TV186_001856"
     CDS             complement(3608..5380)
                     /locus_tag="TV186_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1533217.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(5674..7023)
                     /locus_tag="TV186_001857"
     CDS             complement(5674..7023)
                     /locus_tag="TV186_001857"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL1533218.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         2142 a         1646 c         1450 g         2005 t
ORIGIN      
        1 ttaaagaagg gcatggtgaa tcaatatgat ttctgtaaag aaaaatttat gtcgcttagg
       61 tgttttgtct agtagtttat tacttttaac agctgcaacg actccatctg tcattgcttt
      121 tgcggatatt caaacaagtg ccataaaaaa taatacagat gacgcagatg gtatgtattt
      181 tgttcaaagt tatgaaatgt ctgtagaaga taaagaattg cttgttcgaa atgttaaagc
      241 aaatcatcct acagtttctg aagattttat cagagaagtt attgaaagac aattagtagg
      301 tgattataca ttacctgaag aagagactct tttccgctca gcatggcaag gggttacagt
      361 agatcaattg ggagcagctc tagatgtggc tattggtatg gcattaacag gtggagctgg
      421 atcaattgct gctggtgttt tgagagtcgg aaaaagagaa gctgttggtc gggtaaaatc
      481 aattctaatt aaatatgggc taggtaaaat gatagctgaa attccagtcg attacatgtt
      541 aaatttatta tcgccaggat atcatatagc tagatatatt gatagtattg atacagttcc
      601 taataataat agaattaacc tttggtaagt taggaaattt agtactgtga aaaaaattta
      661 tattttatat tttgtgcttt attgcttatt ataccttgtc atatcattat taattagcta
      721 tggtatgtcc cattttctta acatggaatt taaatggtgg aataaattag ctatatctct
      781 aacatcttta tatattattt atcaaatgct gaaaaaggat aaattaatta aataatcaac
      841 taatgtacaa gttgtcttta agctgaaaag aggctatcaa cagcctcttt ttttgatgat
      901 atagataagc ccaatgcttc cttagaagag ctcttctgtg agatgacctt atcacctgac
      961 attagctgct tggctcatgc ctacagctaa aggaaatgcc ctgcaaggat agcagcactt
     1021 agcctgctgg tctacggcgt gtctcagctg cacctaagcc aagcaaagat ttgtactagg
     1081 ctgccctgcc tgacctgtgg cagccctttg cccttgacat gcagagtacc gggaagagag
     1141 ctggctgtgg agccatcaaa agaaatggtt atatgcccta gctgagcaag atttttttca
     1201 acaacagcac ctactgctgt gatgtcatat gccatttgat caatgactag ctgaccacca
     1261 gcagagatag acccagacac ttgcttgttg tcaatcgtat agcaaaagtc tgccaagtct
     1321 gccggtgctc cctgatcaaa aagaataagc atattggcag cactaatcat gtctgccgcc
     1381 tccgatccaa tagcggtaac tcttgtttca aatactttta tcatacattc tctctcttcc
     1441 tatcatacga tagctcctta ctgatacaaa ccaatacttg caatccaagc aacaacaacc
     1501 cgaggaacac catttaaaaa gcgtgaataa agcacagatg gcaccccaac ctctactgtc
     1561 tcagcattag cctctgataa accaagcgct actggaatga aatcacagcc attttgcgta
     1621 ttaatagcaa aaagtgcagg aagagccatt tgtggtggaa tagtgccttt tccaatctca
     1681 acaccaatga gcgttccgat gatttgacta ataaccgcac caggtcctaa cagcggtgat
     1741 aaaaatggca acgaacagat aaagccaatg ataatcaagc cccaaatatt accagccagc
     1801 ggtaccatga gcttggctag ccaattacca acaccagagc cttggataaa accaattaaa
     1861 agagagacaa atgccatgaa tggcaaaatc gtattgatta aggtctggat agcctcacgc
     1921 gccgcttggt tgaagatagc aactacctta cctgctccca taccaatgcg ggcaacaaag
     1981 ctgctttctg cgcgctgctc agtaatcttt ttgctagtat catagctgct agcctttgga
     2041 actgatgact ccttagcact agcaacatga gcctgagcgt cactggctgt gatttgctca
     2101 agacctacag cagacacgta aatgtcctcg gtaatgtact gtgccaaggg accgctttta
     2161 cctgtcgcca cgatattaat ggttggaatg ccttttttag ggtaaatacc gcagcgtagg
     2221 gtgccgccac aatccacaat agctagggct atctcatcat cagggattga ggtcacaaag
     2281 ccattgaccg cctccatacc tgttagggca gcaattttat cgacaatgtc aggctttttt
     2341 ccaccgccag taatatagat aaatttgtgc ttagcttctg ttggtgtaat ggttagcggc
     2401 ccaccatagc caccgctccc cttaacaact gtaatactgt gataagtcat catgctacct
     2461 ctcttctata attcaatcat cttacttaat gtcacaccct gctgcttggc cacgtaggct
     2521 gtcgtaaagt cagttaccca gccaccaaca aagttcatga ttaacccaac caagaggtaa
     2581 cgaatcgcca agtccatttg gctcaagcct agcgtcttga tacctgaggc aatacctaac
     2641 cagacaaaca attctcccgg attaatgtgt ggaaagacac cgtttgacgt atgacaaaat
     2701 tgcatttgag cggcaacata gcttggcttg taatactcgg gcataaagcg tcccatgctg
     2761 attgccatcg gattacccag cataaaagct gaaataaaag gcaataccat gtagcgactg
     2821 atagggtttt tagcagagat ttttgccaat tgattgaccc tttgatctcc taaaatacca
     2881 attaaggcat tcattgcaac cagcagcatc aagaccaccg gcacaatgcc agtcatccag
     2941 ctgacaaagg tttcaccacc aagctggaag agcttcataa agccttccgc aaatcttgtt
     3001 atcatttcca taaataaact cctcatatga tgtacttaca agcaagacaa tacaaatgta
     3061 ctgcctgctt gataatagct gcttgagctg gactcaaaac agcttttatg ttgacaaggc
     3121 aagcaatcaa tcctgctttt ggcaccttac ttgaagcgtg ccagcagctg cttggcctgt
     3181 agggtccaat caaaggctga ggcatatttt ggtgcgtcct catagacccc tgcctcaacc
     3241 ctcaagaaga cctctcttgc gtcctcaata gccaagcgca gcaatttatt ttctcgtcta
     3301 atcaagggat tgtagcgatc aaaataatga atatcctgac cgatataagc tggcattggc
     3361 ttaaacctgg ctgccactgt cacaccctgc atttgcctag catctaatac cttacctgac
     3421 tgatccaagg caaacatgac aatggttccg gccctgattt tcccggctct acggccaata
     3481 gcaacgcgcc cctgtcgtct aagactggca taaacagcat tgaagtgctt aagctgtctc
     3541 agacctagca ataattgaaa aaggtaagca actatgacaa atagtccaaa aataaccata
     3601 aaactcatta aaaaactcct ttttccttgg taaatgcaat aaactcagct tgacttttta
     3661 ggctccttag ctccgcctga agcttatcat cgcttgctat tttgaaaata tcatcataaa
     3721 ttttcaagag atcagcctcc atctgcgctt caaccctctt ggaaatagcc actagaaaaa
     3781 taaactccac cagacagtca tgctcacgat aaggctcgtc taatagaccc agcagcagga
     3841 cagtctttgt ttccttgtca ttaatcgtat gtggaaaggc aatgcgattg ccaaataagg
     3901 ttgattgcag ggcctcacgc tctagcaggc gttgaccaaa ctgcctgtca accagctgct
     3961 tttcctcaag cagctccgcc atttcagtca ggtagtcagt gtaggccttc ccctttgaca
     4021 gacgagcaaa gtgtagggtg atggtcgcca ggtttttctg gtgataatga tgtaccctgc
     4081 gccattcatt ttgcagccac tggtcatcaa acagatttgt gatttggaga acaggagatt
     4141 ttagctgacc aaacttcagc ggcacagtgg tgaatatggc aaaatagtga tcattgtcat
     4201 caggattgaa ttgctcctca gagaattgtg agatcaacaa atcaggacct agcaccttgc
     4261 tcaagcgacg acaaatcata ttggcagtgc cacgacctgt cgtgcagaca acggcaattt
     4321 ttttcactgt tggctctgtc acatgctcag cgtctttcat catcatttcg aaataaaggg
     4381 ccaaatagct acactcagac aattctatgg cgcagtcaaa ctcctctgct aagacctgag
     4441 ctgcgacaat ggccatatca aaggccaagg ggtatttgta tctaatttct ccatgaaaaa
     4501 tatcattggc ctgaacatga aaaatcaaac gattcaccaa gagcttcaaa tgcgtatgca
     4561 aagcaacaaa aagcttgtct tggtcaatag tcaccaagag actggtcttg atgtgctcaa
     4621 tcatttttga ataaagcctg acaatgctct gttgcagagg cttttcttga taggctagat
     4681 cctcgatgta ttggatattc aagggaaagc taataaactg gcgctcgtat tgactcagtg
     4741 acagctgata ggctagctca atgtgataga ccagctcctc cataaaggca ctggaatcaa
     4801 cctcattgct atagtaagga ataggatctg tcagatacct gccctgacgc attcgctcaa
     4861 tggttatcgc aaagctcttg gtcaaaagct cttggatttt gcgaggaagc tggtaggtct
     4921 gatacagctc atctagaaaa aacaagctat caccacacaa gccctgcggc tcaaagtatt
     4981 tgtaaacctc atgaacataa agcagccgaa ggttcaactc agtgccaaca gcctgtatgc
     5041 catgattggg cttgccctga atcatgaccg aataggtcct agcaagagcc ttggctgcct
     5101 ttaggtcttt attgatcgtg ctgcgactga cgccaatctc atcagccaaa tcatcaatga
     5161 ctaaagctga ggagctttgc agtagccttt ttagaagata agctacccgc ttgctagcgg
     5221 aattaaagtc actagcctta cgtaaactac cagctaatat cgtctctaat ctagcataat
     5281 catagacctg cagctgcaaa aaggcgcctt gttgggtgat ggtcgcatct ccatctaaaa
     5341 tgtcattgag ctgaccaatg ctacttgcag cgtttgacat cgtcttttca caaagtcaca
     5401 gcttagaaag ctagcagagg agacaaaagc aagaccttat cagctaacag cagcatatta
     5461 aacgaacagc tagtgatact gatcctacta agcatagagc tccaaaagcc tggcttaaat
     5521 agtattcaaa atagaacaag agctctcaag aacaataacc tagcgcacta cttgccttga
     5581 taagcctaac cgaccttgaa aagaagcaaa aaaaagagcc tctcacgaga ctctttgtta
     5641 tgttttagca gactagtcta gctagctctg tcattacaag cgtgcgttga gcgctgctcc
     5701 tagctcttca aagcctggct taccaagaag ggcaaacatg tttttcttgt aagcctcaac
     5761 acctggctga tcaaatggat ttaccccatt gaggtagcct gaaagggcaa tagcaagctc
     5821 aaagaagtag atcgtatagc ctagtgtaaa ttcgtcttgc tctggaagcg tgataaacat
     5881 atttggcaca ccaccgtctg tatgggcaag aaggacacca tctgttgctt ttttgttgac
     5941 aaagtcaacg tctttgcctt gtaggtagcc aaggccatca agatcctcag ccatttctgg
     6001 gataatcaca ttttgacgtg gcttatccac acgaatcact gtctcaaaga ggttacggta
     6061 gccttcttgg ataaattgac caagagaatg caggtctgtc gagaaattag ctgaagttgg
     6121 gtaaataccc ttttggtcct ttccttcaga ctcaccagcc agttgcttcc accattcgct
     6181 aaaatactgc aatgatggct catagtttgc caaaatttca gttacatagc ctttgcgata
     6241 gaggatattg cgaactacag catattggta agcgatgttt tctgagattt tatctgatga
     6301 caggtcctta cgagctgcat ttgccccctc catcagcgcg gtaatatcag cacccgatgc
     6361 tgcaattggc aacaagccca cagctgtcag cactgaaaaa cgaccaccaa cattatctgg
     6421 cacaacaaag gtttcccaat gatttgcatc agcctcaacc ttaacagcac ccttgacctt
     6481 atcagtcgtt gcatagatac gcttgttggc ctcttcttga ccgtactttt taacaagtaa
     6541 ttctttaaag acacgaaagg cgattgcagg ctctgttgtt gtaccagact tagaaatcac
     6601 gttaacagag aaatctttat cttgaacata gtccacaaga tcagcaagat agcttgatga
     6661 gatggagttc ccagcataaa gaatttgtgg tgctttgcgc tcttttgctg tttgtaggtt
     6721 ggcaaaatgg ctgttcaaaa agtcaatcgc agccttagca ccaaggtaag agccaccaat
     6781 accaatcaca acaagaacgt cactgtcagc cttaatcttc tcagctgctt taaggatacg
     6841 agcaaattct tctttgtcat agttttcagg taactcaagc cagcccaaga aatctgatcc
     6901 aggtccagtg ccctgacgta gtgcctgatc agcctctgtt acctgacctt gtaaaaagtc
     6961 aatttcatgc tgtccggcaa attgctcaag aacctttgaa taatcaaatg taatatgtga
     7021 cattatttta ctcccttaac ttttaaagtt tcattagtat cataaccttt tctattcaat
     7081 atttcaatgt tttttatttt tggggagggt ggcctgactt taacgacatg aggatcattt
     7141 ctgtctaaaa gcagctttgt gatgagccta gcgcttccct atctgcttct actatagctt
     7201 actggggctg atccgggtga tgtggtagcc tcttggcata gcc
//
LOCUS       DARYXZ010000073         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYXZ010000073 DARYXZ010000000
VERSION     DARYXZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(25..486)
                     /locus_tag="TV186_001858"
     CDS             complement(25..486)
                     /locus_tag="TV186_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL1533219.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TV186_001859"
     CDS             complement(530..1606)
                     /locus_tag="TV186_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1533220.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TV186_001860"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TV186_001860"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL1533221.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TV186_001861"
     CDS             4915..5859
                     /locus_tag="TV186_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL1533222.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            6118..6768
                     /locus_tag="TV186_001862"
     CDS             6118..6768
                     /locus_tag="TV186_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL1533223.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1998 a         1792 c         1334 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attaccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYXZ010000074         6627 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYXZ010000074 DARYXZ010000000
VERSION     DARYXZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6627
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(36..3146)
                     /locus_tag="TV186_001863"
     CDS             complement(36..3146)
                     /locus_tag="TV186_001863"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL1533224.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            3388..3759
                     /locus_tag="TV186_001864"
     CDS             3388..3759
                     /locus_tag="TV186_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1533225.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            3759..4457
                     /locus_tag="TV186_001865"
     CDS             3759..4457
                     /locus_tag="TV186_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533226.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            4467..5261
                     /locus_tag="TV186_001866"
     CDS             4467..5261
                     /locus_tag="TV186_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533227.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(5308..5919)
                     /locus_tag="TV186_001867"
     CDS             complement(5308..5919)
                     /locus_tag="TV186_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1533228.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            6010..6358
                     /gene="ssrA"
                     /locus_tag="TV186_001868"
     tmRNA           6010..6358
                     /gene="ssrA"
                     /locus_tag="TV186_001868"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         2054 a         1442 c         1168 g         1963 t
ORIGIN      
        1 attcgtttgc aaattacttc actaattcgc tatttttatc gaaaaaccgt tttcaacacg
       61 taggggctaa tagcctcctc caaatcctta ctaacatcaa ccctaatatg gtttaactct
      121 aaggtttctt tgccttcttg ataatggata ataacaggag tctcccctga aaaggctgtt
      181 aatatgtcag aaatagcagc atcatgctga tggttttcaa ccaatagcca atacctttga
      241 ctctgagcta atcgaagctg gtgacagact agctgcaagc ggttatctct ttcttttacc
      301 ctgccattga tatagtaaat atgcccctct tttaggtctt gcttatagac agcatattgc
      361 tcaggaaaaa gggtaacatc taatttctgt ttggtatcag taacactcaa aaaggccatc
      421 tgctgtccgc ttgattttgt ccgaataacc ctgatcgcat ctatttgaac cagcaaagta
      481 gcttctgtat ccttcactaa ctttgtgatt ggtgtgactg ctactgtgct tttttcagcg
      541 acagctagca aggggtgctt gctcatgcca acaccaagca aatcctgctc aaagtaatat
      601 ttctcagcag ctgaataatc ctcagtctct acccagctaa aggaggaatc cgcaaaaagt
      661 gatcccaatt cattgacaaa ggttagcagt ccttctaagt tgttaatgat tttttggcga
      721 tttttttcaa acccatcaaa caggcctatt ttgataaggg gctctaagaa gctggttttc
      781 tggtattttt caggaatgct gcacaaaaag ctttcaacac tggtaaaggg cctattttca
      841 atgatccaat acgaaaattc tctaggaaga cccttgatgt tttttaagcc catataaatc
      901 ttatgacgct caatcttatc attgaaggga atggtgttta tcgtcacctg cgcggcctca
      961 aagccaaaat ctaacgcatc tgtgatgtaa tcactgctag aataattcat catgacatca
     1021 aaaaatacct caggatagtg cgctttaaaa taggctagct gaaaggctag ggcagcataa
     1081 gcaaaggcat ggctgcggtt aaagccgtag cctgcaaatt tttccatacg tgcaaacaat
     1141 agtctggctg tctcctcaga gcgacccaag gctctagcac cagtcagaaa atcctcctgc
     1201 attctttgca tctcaacgag gtttttctta gacatagcac gccgtagcaa atcggccttt
     1261 ccaagtgtaa agcctgcata aacttgagca atctgcataa cctgctcctg ataaagcatg
     1321 ataccatagg ttggctctaa tatcggagca atcaccggat ctattagatc aatgttttcc
     1381 tgtccctgcc ggcgcttaat aaaattctgc gtgtaatcac ttgctcccgg tctatttaag
     1441 ctggttgtcg caacaatttc ctcaaagcta gtcggcttga tccgttttaa caggctaatc
     1501 gcaccatgct gttcaaattg aaaaatgccc ttggtatcac ccctagcaaa caaggctatc
     1561 gtttcaggat cctctaggtt aatagcttca atgtcaattg aaagaccgta atcgttgacc
     1621 accttttcct gcattttctg tacaagcgtc aaatttctca gaccaagaaa atccattttc
     1681 agcaagccat tagcttcaac agcactggca tcatactgag tcaccatcat atcctccccc
     1741 ttttttaagg gaatatggtt ggtcagatgg tcatcactca tcacgatacc agcagcgtga
     1801 atagaggtct gtcttggatt gccttcaatg cgcttagcta tctcaaatgc cttttgaaac
     1861 tctaagcggc tattaatggt ctgtctgaag gctatatttt tctcataaac agtgctcagg
     1921 gtatccttga acccaatttt tttagttagg cttgttagct cgtattctgg gacaccaaag
     1981 cgtttgaaca catcacgaac agcctgctta ggaccaaaag tcgaaaaggt aacaatctga
     2041 gctgagtgct cactaccata ccggtctcga acataatgaa gaaactctga gcggtaaata
     2101 tcaggcaaat caatatcaat atcaggcatg ctgtagcgtt ctttattcaa aaagcgttca
     2161 aacaataaat tgtttttgac aggatcaatc ccagtaatgc gcaacgaata agccactaga
     2221 ctgcctgctg ctgaaccacg ccccatgccc atataatagc ctctactcct tccaaagcgc
     2281 agcaaatccc agacaatgag aaaataatca tcaaacccca tatctgaaat aatagccagc
     2341 tcctctgcca gacgaaattg gtaaggctcc ttccataatt gcttttctct tagaccagac
     2401 tcggtcaatt ctcttagctc ttcttttgct ggcttatcgc ggttaaatct cggaagcttt
     2461 aaatcagtat caaaatgata agcaatcgaa gctgttagat ttacgagatt caccaaagcc
     2521 tcagggcact tttcctggaa aatagccgtc atctcctgac aaggcgctaa aaactgatcc
     2581 ttggctacta gagccgtatc tgctaagcta atattatcac gaatggcatg cagcatttgc
     2641 agagtctcag tctcagcatt atcaaaataa cgtaccgttc taagcggaat cagtctttct
     2701 gtagagtcta tctttgacaa gtcgcttgcc tcatcaatgc caatgaagta atcaaaagga
     2761 agccctaaat cacgcaagct ctgactaaaa ggaacgataa ctgctatccc ttctaaatac
     2821 tgcaccaatg tgtctaggtc taggtctcca gacatttttt cagtcgaaag ctttaagagc
     2881 tgctgatagc ctgtatcatt tttcgcaaca agcttcagcg taagagcctg ctctttaact
     2941 gtaatagcca cctcaagacc taaaatcggc tgaagcccat gcctttgaca gcccttaata
     3001 aaatgatatg ccccatatag attatcctga tccataatcc ctatggcttg atagcctaat
     3061 cgtttggctt gtttaaaata atggtctaaa tcaatcaaac tatccataaa ggaataaact
     3121 gtttttgtat ctaactgagc aaacatggac atctccttta gcgttcttac taccattata
     3181 ctatgaaaaa gactttactg cccagatttt aagcttttaa tagcagtgat ctgtctttac
     3241 tgcaccacta tcagcaggaa tcccactagc attgcaagcc agtatgtaac tagagatgac
     3301 acacaaggct tgacaagtca atcgtttttt tgtatcattt aattagtaca aatattaatc
     3361 gcagatttta gaaagaaagg agacagtatg tcttggaaat ttgatgagaa atctcctatt
     3421 tacgcacaga tagcacagca tatcatgctg caaattgtca gccaagagat caaaagtgga
     3481 gatcagctgc cgactgtccg agaatatgct gaaattgccg gcgttaatcc caacaccatg
     3541 caaagagcac ttaccgaatt agatcgtgaa ggcatagttt actcgcaacg aactgccggc
     3601 cggtttgtaa cagataacca agagcttatc gcgcgcaaaa gacgagagct ggccatcaac
     3661 gagctcaagt cctttattag caatatgatc aaaataggtt ttgaacgttc agaaatcatt
     3721 cctgttttaa gtaccttttt agaggaggga tcaaactaat ggcacaacta ttacagctgc
     3781 accacgtctc aaaatcttac aaaaaacaat tagctattga tgatttaacc ataacaatcc
     3841 cttctggaaa aattatcggc ttactaggac caaatggtag cggcaaaact acactaatta
     3901 agctaatcaa cggactttta cagccagaca agggagacat tgttattgac ggctttagac
     3961 catctgtaga aactaaaaaa atcatttctt acttaccaga tacgacctat cttaatgaaa
     4021 gtatgaaaat caaggatatg ctagactttt ttggtgattt ctatgccgat tttgacagag
     4081 ataaagcgac cagtctcctg aaggatttag acttagatgc tgaagagcgc tttaaaaacc
     4141 tatcaaaggg aaataaggaa aaggcacagc ttatcctcgt gatgagccgc aaagcaaagc
     4201 tctatatcct tgatgagcct atcggagggg ttgacccggc agcaagagat tatattctta
     4261 aaaccattat taataattac tctgagcaag cctctgttat catttctact cacctcatct
     4321 cagacattga gcctgtactt gatgaagcta ttttcttaaa aaatggtaag ctctgccttt
     4381 ctggaaacgc tgatgattta cgagttcagc atcagcaatc gattgattca ttatttagag
     4441 agatctacaa ggtttaggag gtaggcatgt ttggaaaatt attaaaatac gaatttagat
     4501 caattggcaa gtggtatttt gcgcttaatg ccggtgtcat tgctatcgcg atagtccttt
     4561 cttttaccat caatacgctt acaaacaatc ctgacgaggt tggtttaaca acaagtctgg
     4621 caaacaaaat ggttcctctc acactctcat taacgtttgg ttctctgatt gccggatcat
     4681 tcttatcaac gctattaatc atcattaatc gctttaacaa aaatgtcttt gggcgcgagg
     4741 gatacttaac actgacacta ccagtaacag cacatcagat tatcttgtcc aagctgttag
     4801 cgtcctttgt ttgcagtatt tttaatggca ttaacctatt aatcggtatc tttattttaa
     4861 tagcgccaac agttgacttt acctatctac taaaggtgct aaagacaatt atgaagccag
     4921 aaaacttagt cgaaaatgct tctatcctca tctacatgct tttgtcaacc ataacaagta
     4981 tactattgat ttatctagca atctcaattg gtcagctatt ttcaaatcgt cgtggtttga
     5041 tggcattttg tgcctatttc attttagtta ttatcattat tgtcgtcatg acttatttaa
     5101 atgatgcgtt tttcaccgtc aacccaaata gctcagactc gctactctat ttcggtgatc
     5161 atacagccat atctatttta aacatagagc aactagttga aggcattatc ctttacgttg
     5221 ctactcactt catcatcaaa aacaagctta atatccaatg ataacaaaaa gtctagccac
     5281 tgcttatcag gcaatgccta gactttttta atggaaaaac cataggatca aatcctttcc
     5341 aaagataaaa agatagctgt agccaataat tgatagtggc ttcgtgatta aaataatggt
     5401 cacaaaacgc ttcaacgaca tctctgtcag cccagtaatc atgaccataa tatctgctgg
     5461 tgaaatcgga gaaagcatac agagaataaa caatctctca taatatggca tctctaattt
     5521 tctctcatac ttgtaaaagg tctgttcctc tataaacagt aaaataaagc gcctaccata
     5581 ggtcttcaca agtaaaaaca gaatcacact accaatgaag ataccaacat agttataaag
     5641 aaaacccagc aaagggccaa aaatcaaaaa gcctgcaata gttgtcatac cacctggaat
     5701 aataggaaaa acaatctgaa caatttgcac accgacaaaa acaagggggc caaaaacctt
     5761 gtgactatga acaagatcct tgagtgcatt gctgtcattt aaaatgccaa gcctgtaaaa
     5821 ccaaaaggct agcaaaaaag atccgactaa agccagactt cctaatagct taatcacttt
     5881 ttgccatatc acataaggct tcaactcatt atttctcata gcttcatcat accataagcg
     5941 ctattttttt gccattttaa aaaaattttg ctatactagc atccgtaagt atctcatacg
     6001 cctttttatg gggttgttac ggattcgaca ggcattatga ggcctatttt gcaactcatc
     6061 ggcagatgta aaaatgccag ttaaatataa ctgcaaaaaa taacacaact tacgctttag
     6121 ctgcctaaaa accagccggc gtgacttcta taggattgct tgtgtcttat tagaggtctc
     6181 aaaacagcaa gctacgttta ggtgattgtc tagtcaccta aaaagagaac cctagactcg
     6241 caggctgatg gcttgagtta tgtgtccttg gtctgttaaa gtaagacata acctatggtt
     6301 gtagacaaat aggttagcag gtgtttggac gtgggttcga ctcccaccag ctccatcaat
     6361 acttaccgta agttaccata acttactaaa accttgttaa atcaaggttt tttctttttg
     6421 tcctgttcgt gggttaccgt aagtttctat gaaagtgata gcaaaaaaaa ggccaaaaaa
     6481 tcctttaaga acagcttgaa ttttctcttt agctaatctt atatttattt ttttataata
     6541 cttcttctac ttgcttcatt gacagcacat tatcaaattt tttcggataa ttgccctgta
     6601 ttgcctgtta tatagacatc atttact
//
LOCUS       DARYXZ010000075         6540 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYXZ010000075 DARYXZ010000000
VERSION     DARYXZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6540
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            198..1811
                     /locus_tag="TV186_001869"
                     /pseudo
     CDS             198..1811
                     /locus_tag="TV186_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
     gene            complement(1832..3763)
                     /locus_tag="TV186_001870"
                     /pseudo
     CDS             complement(1832..3763)
                     /locus_tag="TV186_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003656745.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
     gene            4820..6334
                     /locus_tag="TV186_001871"
     CDS             4820..6334
                     /locus_tag="TV186_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1533229.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT         2019 a          924 c         1248 g         2349 t
ORIGIN      
        1 cagacttgac aagtgggggt gttttcgtga ggtaaaaaca tgtattaaaa tagctacata
       61 gtagccccat taaataagaa atgttgttgc tttgtgataa tgctaactgg aaggattaat
      121 tatatgctat aataaagata ataagtataa gattaaggag ctcttatgaa aataagaact
      181 tatggttggg tacagatttc tttgaagtac cacgagaatc actcagaaac aaactgatta
      241 atgggattca atcattttca tatttagaat tagttggaac atcaaaggat aagaataaca
      301 aatctccccg aaagcgttca gatgcaatgg cagattcttt gattcaaatc agcatcgtac
      361 ctcaacaggc aaaaaataca ggtaaaactt ggacggataa ttggacatca gatggttttt
      421 taagatgggc tgttagcctg aattttgtgt cggtagatag agaaacggat atgttttcaa
      481 ttacttcgaa ggggttgcat ttttctaggg caataattaa ttcggaagaa gaaactgcta
      541 ttttaagaaa ggcactgttg tcatacccgc cagctacaca aatcttatct ttattggctg
      601 atagcggtac ttattgtact aaatattatt taggtgagca gcttggtttt cgtggtgaaa
      661 aaggctttac ttcctataat gaagatatta tgtttgattg gttaggatct gccactaaat
      721 cagagaaaaa acttattaaa gctgatatag aaggaacaag tgataaatat gcacgcggta
      781 tttgtaattg gctaaaaaat gttggtttgg ttgattcaca aacgattaag cgtaccttta
      841 ctaatggtga aaaagatgga tttcaaggtt ataaaattaa tggtcgtggt cttcatgctt
      901 tacgacaagc tcagggggat tctaagcata gcaagcttga aaaatttgtg atgtgggaat
      961 tttttgcaac tcatggcaat aatcgcgagt atgttcgtac tcggagagct tatatcgtca
     1021 agtttctcca agaaactaat tctttggcta ttctattaga taaactaagg gctaagggtt
     1081 tttacgatga actggagatt atcttatcag atattcaagg attgaattat tttggtttga
     1141 ggatagatat ttctagcaat agagtttctt tgaaggataa gatcaacgat ttttctattc
     1201 ctgaactaga aattacacaa gaattaaagg atgagcaggc agaaaagcgt aaggcaaaat
     1261 ttttaaaaga gactaattta ccaatgaaat atattgaatt gcttgatatt gcttacgatg
     1321 gtaagcgaaa tcgagatttt gaaattgtta caatggaatt atttagaaat gtatatagat
     1381 tgcattctaa gcttttaggt ggtggcagaa agccagatgg tttactctat caagatcgtt
     1441 ttggtgtgat tgtagataca aaggcttatg gaaaaggtta ttctaaatct atcaatcagg
     1501 ctgatgaaat gattcggtat attgaggata ataagcgacg agatgaaaat cgtaatccga
     1561 taaagtggtg ggaagctttt ccagatacga ttccacaaga agagttttat tttatgtggg
     1621 tgtcaagtaa attcattgga aaatttcaag agcagcttga ttatacctct aatgaaacac
     1681 aaattaaggg agcagccctc aatgtagagc aattgctttt gggagcagat ttggttctta
     1741 aaggacaact gcatatttcc gatttaccat cttattttca aaataaagaa attgaatttg
     1801 taaaagcata gctaattcaa ctatgctttt attattttgg atttggttta taattggtaa
     1861 tcaatacttc aatgctatct tcttttcttg tgttgtatga agcattttta taattgtaat
     1921 ttaaagtggt gagatataga ctttcatctt gaacaaattg ctcaagtaaa tcattgtgct
     1981 ttcctttatg aacaagaaca ttactaagtg caaccttaat ttgtttcttg ttaaggtctc
     2041 ttattaattg atacatttca atttcttgtt tttcgcccca gtttgtgaag ccacgatttc
     2101 catcattata gctgccagtc gttatgaggt aggggggatc aagataaaca aaatcatcta
     2161 ttgataatgt agaaatatca aaatctgaga aaaattgatc agagaaagtg gcatctaaac
     2221 ggtgtagtcg agctacaaaa ttgagtagat tggatttcat attttcacta aaatgacttc
     2281 tatttctgcc gaatgggtta ttgaattcca ttgagttatt aaagcgaaat tgatagttat
     2341 agctataaga cgatagtacg tataagtcta gtggatttgg atgagtatta taatgttttc
     2401 ggaatgttaa aaagccttgt tcattggtct tgctgagttg atattctgaa attcgatgct
     2461 caatttgttc aagtatctca agtgggtcat gtgattgaaa atatcgaaac atgtcattaa
     2521 tgcgatagtt catatcatta aagatgtgtt ttttagcagg aacattgata ccaacgtttg
     2581 ccccccacta aacatatcaa caaatgtatt gatatgtcgg ggaaaaattg gaatgatttg
     2641 atttagcagt cgatattttc caccgatata atttaatggg ctttttatat actttttttg
     2701 actgatgatg gctgcctttt ttttagtttg tgatttgaag cgattattta tcggctttct
     2761 ttgaatataa aaaagaagtt cgtataagtc tttgttctga gattttttct tagattgata
     2821 ttttcggtaa ggaatccgtt tcacatcaat ttgattattg aacgaatatc gttgaagtaa
     2881 aagtgttaaa tcttcttcgg atataatacc ctcggtattg taacttagaa tgatatgact
     2941 agcattaata ttagcaatta aatcttccat tgcttttaaa gcctttgttt ttgttgaata
     3001 atcactttta agagttttcc aatcaaaaat tttagtaatc ccttttaaaa ttggcttttg
     3061 atgtcgggcg atgttttcga gtaaatgata atttgatgcg tattgtcgag cattgtaggg
     3121 ggtatcaatg taaacaatat ctgcttttat ttttttgact aattcattag cattttcatt
     3181 aaacgctttg ttaggacgat aattatcaaa aatagtctct tctgctaatg ttaaggaatg
     3241 caacgctcgg ttgtcccaat gcttgagaaa agcgccatag gttccagtaa tattactaac
     3301 ataaggaata gcttctatca aagcatttaa aaggtaaaaa tattcgtact ctgtgagtaa
     3361 ttgattgttg ttccaatctt ctatgatctg tctgatatta tcaatttttt cagtattttc
     3421 ttgtgttaga tacatacaat ctcctagagg agagtaattt tttgtgtaat atccaatttt
     3481 accattaagc ctttgtagat aatcaattgg atctaaaatt cctactgctt ttagtttatt
     3541 aaaggatagg taagaattat tttctataat agcctttgct ttaacatagt taaagtataa
     3601 aatatcatta gaataaacag tataatattg tttaaagaag tttgaaacca cattagtgcc
     3661 tgcaaataaa tctaaaaaaa acttcttcat caccagtttt atgtttgtct agcatggtct
     3721 taatttctgt caacaataat tttttagaac caatatatct cattctacat ccttaatcat
     3781 cctttagttg tttcattata gcatattcat gttgaagttc caatatttta tttgaaaaat
     3841 tatcttttgc tgtatttctt tattgtagtt tttaagctta gtttatatgt tgttgattaa
     3901 agggaagaag aacttaggtt atctaaattg aggaattcgt ctgtaggtaa caatgtatta
     3961 tgtggccgag agatttattt tatatattaa tgagatataa gacccctatc ccgtccagcg
     4021 tgacagactt gctatggaaa agcttatttt gaggctgtct gaggcttgct tatgtgtgac
     4081 aagcatttag gctagaacgc tcaccttttt tactgcaagc aaagctttag aagctattgc
     4141 aagatacttt taggcttgtt actaagcggg tcatctctat catctcctag agagtagtgg
     4201 aggctatgac agtttagcat atatggtttc tctaatgatt tgacgatgta aaaccataac
     4261 tactgttatt gtagggatta tgtataatat gtataaaaag agaagggctt gtttctcagc
     4321 gttatcattt tacctataat gtcgctgcca gtttgcaagg ctgctgagat tagtagcttt
     4381 ttggctattt ttctcatctt ttgtcttatt tttattaaaa ataatgaatt tataaagata
     4441 atttttcaaa gaatagtctt taagttgaca gtagtatcat gtggcgattt ttgtcttggt
     4501 ttttgcattt atttcggttt ttttatcttt aattaagtta ctaatattct gattatgtta
     4561 gtaaaatgac attctcataa aatgtctaaa aaaggctaat ttgtcaaggt attatcataa
     4621 ggcttgattt tataagctat tgactgtata ctcttatagg ttattttata aaatattttc
     4681 agtctttttt atttatcatt ttcagatgat ccttgaaagg aagcagtcgt tattttttgt
     4741 gtattttttt tagttgactt ttaaatccta tcaactaaaa tgtatatggt catacaaact
     4801 aataaggaga gagattattt tgttagatta ctatttagaa agagatattg ttgagcgaaa
     4861 actaatattg gctgtcttat tgacagaaaa agagattaca cttgattcat tgtgctcgca
     4921 gacgtcaata acccctcgaa aggctaagga ataccttaat cagattaatg cactatttga
     4981 caaagacctg tctattactg tattgaagtc aggcattacc tgtgagtttg atcctaataa
     5041 caaggagaag tattttcaca gtatttatgc atcatctgat acgcttaaaa tgttgaagtt
     5101 tctgttgacg gataattaca ggacaaagtg tctgacaact ttcatcagaa gacagtttat
     5161 ttccaaatca aaggcctatc atcttgtcaa taagctaaag ggctacctgc aatccattca
     5221 tttggatatc gatgattacc gggttatagg ggatgagtac cggattcgct acttaattgc
     5281 catgcttcat aaggagtatg ggtttgctgt ttatgagatg acacctaagg atatggaaat
     5341 tattcatgcc tttatttttt taacccctac gcggttaaag cccactgttt tcttggacaa
     5401 gaaattttat ctttttgata ttttactcat gctgtcttgg aagaggcaga attatgatgt
     5461 atccttacca cagcttactt tatttgatcg tttaaaagaa ttatctattt ttgagcaaat
     5521 cagttgctat gctaagcaag aaattgagac acgtactcag gttgtgttta attctggtga
     5581 cttagattat ctttacttgg tttatcttac agttgatagt tcttttctta tgcattattg
     5641 gaatgacaag caattacgtc ttgtctacaa tatcttagaa gaagatccgc tgtataagga
     5701 gcttgttaat cgcttggaaa tgttgtttgg tcgtcagctt catttaaggg atcagatgta
     5761 ttttttgctt ccctttttca gaagatgtct ctttcaattg catgatttga ttagctttca
     5821 ggattactat tcaaagaggt atcaaggcag tcagctgctg ctagaaaagg ttgaggagca
     5881 aatcaaggac tggctgatgg ttagctacca gtcagaaacg ctctcaccag ggcacctgca
     5941 ttttatgtgc cttcatttgg agcagatgct tgagctgtcc ttgccgcctg tagaggtcat
     6001 catcgttgaa aacaagagag cattaggtga tgtcttgtct tactttgtta tctcaagtat
     6061 tccttcttat aaggttaata ttactcgtat caacatgcta acagatagtc tggaaaatta
     6121 tgagcaggct cctgattttg tgattacgag tgataatatt ttgccttttc ttgaggagca
     6181 gcaggtattt ccagataaga gcgtcttaat tggtatgagc atggattaca ttaaggagca
     6241 gggaaaaaca gtggtaaaat caattctgaa ctttcatcgt aagcattacg agcagctttt
     6301 agagcagctc ttgattggag atagggtaga gtaagttttt ttgctaagca agtggtataa
     6361 ggctgctagg tttttctttg gaccattttt tgtgaggatt tgctttagcg atacctgttt
     6421 tgattggctt actgctgatc gtgataacac ctatgctaaa tagcagcaat caatagctcg
     6481 tgcctatttg gtacaatatt tctgaaaaat ccacttgtga taagcctttc aagtggattt
//
LOCUS       DARYXZ010000076         6322 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYXZ010000076 DARYXZ010000000
VERSION     DARYXZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6322
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..3093)
                     /locus_tag="TV186_001872"
     CDS             complement(<1..3093)
                     /locus_tag="TV186_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL1533230.1"
                     /translation="MELNNIKERAKELVKDWLKSIFVEKVVSENENLIEKGLSSIQVM
                     QLSGKLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQSDESKFDLTD
                     VQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDG
                     KQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFS
                     DEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQNGIGESIND
                     ADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETIKDIAASYRS
                     TPSMVLLTAYALVLERWCNQDKFFINIPLFNRDLENENLKEMVADFTNILLVEHEAVD
                     DSNFLDNLKRINKTFLENVSHSEYNGVQVQRDISKKQGTSVYIAPVVFACNIDYPLET
                     EFSRKNLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYE
                     LIISLTQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRV
                     AIIDSETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFT
                     GAAYVSIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVA
                     KLKQPVEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMV
                     SAIDFDLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMI
                     VTMAEGKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHL
                     NVPRKIPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEE
                     LTNKKYFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVF
                     ENIKKAIALIVKDGNVNKLVGFAEIFDCKESNQMLLNSDFEKETEEYKKQKDEYINFI
                     D"
     gene            complement(3108..4691)
                     /locus_tag="TV186_001873"
     CDS             complement(3108..4691)
                     /locus_tag="TV186_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1533231.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEAVAYISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYK
                     NFSSLIENDCFYKYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNV
                     NQESVYLASLPIAHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGF
                     VPAIANICMDYLEYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGL
                     ILTTNEEDNDKIRWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYN
                     LPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTH
                     ENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYID
                     AWPLTALGKIDRNKLKETF"
     gene            complement(4700..5266)
                     /locus_tag="TV186_001874"
     CDS             complement(4700..5266)
                     /locus_tag="TV186_001874"
                     /inference="COORDINATES: protein motif:HMM:NF013786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HEL1533232.1"
                     /translation="MIKDLKNFLKEEEIEKLDAYKSEVAKINFAVSRSLLNKVFEMIL
                     GVPIENIVSFRDKHNKPYIENKSGVKFNISHTDGFVVIGFSKKELGIDIEKVNDGFAF
                     EDILENCFTSREIKNIGSNIPMFYRYWTAKEAYLKYEGYGLIRNPKEIEVIYIDNQRI
                     KIEDKVKRSNKDLIAFSISSKYFGAICI"
     gene            complement(5370..6119)
                     /locus_tag="TV186_001875"
     CDS             complement(5370..6119)
                     /locus_tag="TV186_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL1533233.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPESVIKAIEEFVYSNENI"
BASE COUNT         1950 a         1314 c          680 g         2378 t
ORIGIN      
        1 atctatgaaa ttaatatatt catccttctg ttttttatat tcttcagtct ccttttcaaa
       61 atctgaattc aataacattt gattactttc tttgcaatca aatatttccg caaatcctac
      121 aagtttatta acatttccat ctttaacaat taaagcgatc gcttttttta tattttcaaa
      181 tacaattaaa gcattctcta tttctccaag ttctattcta tgtcctttaa cttttacctg
      241 agtatctttt cttccaagaa actcaataat cccatcattc catgttctac cattatctcc
      301 agttctatac cacctcatcc catcttgttc gaagtacttt ttattcgtta attcttcgtc
      361 accatgataa catttagcaa caccaactcc accgataaga agttcacctt taacataatt
      421 agggcagatc ctaccaaatt catccacaac tctatacact tgatttttca aaggtctacc
      481 atatggaatg gaaatccaat ctttcggtat ttttcttggt acattcaaat ggtttgacca
      541 aatagatgct tctgtggctc cacccatagc gacaacaata gaatttatat tttcactaat
      601 attatagaat ctttctggta aatttatagc aatccaatcc cctgaaagca tcacaattct
      661 aaaaggtaag tttctatttt taccttcagc catagtaaca atcatatcaa acaaaatcgg
      721 cacagaatcc catattgtaa ccttatattc atcgactaaa tttaaccatt catcaggatt
      781 tctataatta tcttcacttg ttgtaataac cgttcctcca gcatgaagta ttccaaaaat
      841 atcataaacc gacaaatcaa agtctattgc cgacaccatc agtattgtat cttcagcatt
      901 tacattgtat ttttcattta aatcaatgca agtattaacg gcacttgtat gcataatctc
      961 aacaccctta ggaacacctg ttgttccaga cgtcataata atatacgcac tatcataagg
     1021 gctaatttca acaggttgct ttaatttagc cacatttgcc atagctacat ccaaatcaat
     1081 aattttaact tcatttttat ttaatttaca atctatcact gtcttttcat cacttataat
     1141 gcactttatt ccgatttgat cataaatttt agttcttcta tcatttggct gagcaatacc
     1201 aattgataca tatgctgcac cggtaaataa aatcccaaaa atagcataaa gttgtctgct
     1261 acctcttgga agtgttattc ctacataatc tcccttttta acaccatttt tacctaaaca
     1321 atccgcaact tttaaagaga tttcataaag tttatgatat gttatctctt ccttcgtttc
     1381 agaatctata atcgcaactc tatctggatt gagttttaca tttctgagaa atccgtcata
     1441 taacgtttcg ctaggatatt gaagtggtaa aattccctca acatcctgca ttctaataga
     1501 cttttgcttt tcaggtaaaa catctacttt cttttcccat tcttccttct gtgttaaaga
     1561 tatgatcaat tcatataaag aatccatcat gtcttctaac attcctgttg gaaaaagttc
     1621 atccacgcta tcccagcaaa gaattaaatc tccatctaca atatatgttt gaaaatcaag
     1681 ccaaactcct ggtgtttgag aaatcatata agatactttc cctaaatttt ttcttgaaaa
     1741 ttcagtttcc aatggataat ctatattaca cgcaaaaacc acaggtgcta tatacacact
     1801 tgtaccttgt ttttttgata tatctctttg aacctgcact ccgttatact cactgtgaga
     1861 tacattttcc aagaatgtct tatttattct ctttaaatta tctaaaaaat ttgaatcatc
     1921 tacagcctca tgctctacca ataaaatatt tgtaaaatca gcaaccattt cttttagatt
     1981 ttcattttct aaatctctat taaatagcgg tatattgata aaaaatttat cctgattaca
     2041 ccatctttca agaacaagag cataggcagt tagaagaacc atagatggtg tacttcgata
     2101 cgatgctgct atatctttta tggtttccca ttcacttttt ttaataattc tctttcttct
     2161 tgtaaacttc gtttctttaa tttgttccgg ctgtttcctt aatggtaagt tcggtctttc
     2221 tatttcaaag gaatttattt tttgttccca aaactcctta tctgcatcat tgattgattc
     2281 gccaattccg ttttgcatat aatccttaaa cgtatactca ttcaaattat caagttctac
     2341 tcctgaataa agttcagcta attctttaat cataatactc atgctcatta catcggatac
     2401 aagcaaatct acgtcaaaaa atatccttga cttctcatct gaaaattttg ctagtgctac
     2461 tcctgcaacc tgaccttgat ttacatttaa tttcctatga gatttttgtt ctctaatttc
     2521 tactaatttt agatgcagcg tttcttcatc aagatcagat aaatcaaaaa cttctatttc
     2581 ttcactgtac ggtttgtata atatttcctg cttcccgtct ttcgtaaatt ttgttctaag
     2641 catgggatgt ctgtattgaa gcttattcca agcctctttt aacttatcct catcaatatt
     2701 ttctccatct atttcaagat atgcatggca acccacgcca cctaaaatct gatcatcttc
     2761 tcttccgatt aaataggagt actggacatc tgttaaatca aacttacttt catcactttg
     2821 gataattgat gactctatat tcttatcact tttcactctg gatttatcaa taagttcata
     2881 ccacttggac aaattcggtt cttccataag ttttgcaaac gaaattttta tccccgtttt
     2941 ctttaatttt ccagacagtt gcatgacttg aatggaactt aaaccttttt caattaaatt
     3001 ttcattttct gaaactactt tctctacaaa tatacttttc aaccaatcct ttactaattc
     3061 tttagctctt tcttttatat tgttaagttc cattccaaaa tcctccttta aaaagtttct
     3121 tttaatttat ttctatctat tttccctaaa gctgttaatg gccacgcatc aatatattta
     3181 acagtatccg gcaatttaaa atccgccaca ttattagaaa tcaagaattt tctaacttct
     3241 tccagtgtaa gctccttatc tccatttaaa ataaatacag caatggattc tccttgcaga
     3301 cgatctggca gccctacaac ttgtaccgag ttgatatttt catgagtaag caaaatttct
     3361 tctaattcaa gtggtgttat cttttcacct gctctattga tgatttcttt gatccttccg
     3421 acaatttgat aattaccatc ttttagtttt cgtgctttat caccagtctt aaaataacaa
     3481 tcttgtgtta tacatgtttc atttacttca ggaagattat aataaccata aatggtataa
     3541 ggacctctaa cgataagttc tccatattct tcaatcccta caatttttcc ttgttcatcc
     3601 acaatcagta tttcatcatg ttcactgatt ggtttgcctt gtgtttgcca tcttatttta
     3661 tcgttatctt cttcatttgt tgtcaagatc aatccttcag cgattccgaa aatctgttgt
     3721 agtttaacat caaaaacttt ttcaattttt tctgccaacc aaggttccaa aactgaacct
     3781 ccgacttgta taacctccaa agaggaaaga tcatactctt catactctaa ataatccata
     3841 caaatattgg caattgcagg aacaaatcct gttatcgtaa ccttttcttc ctcaattaaa
     3901 ggtaaaattt catcagggct tgtcacattg cacaaaacca cctttccgcc ttttgcaaaa
     3961 gtacccatta tccctggaca ccccaaagga aaattatgag ctattggcaa agaagcaaga
     4021 tatacacttt cctgatttac gttacaccgg tccgtcgttt tctttgcaac atagatataa
     4081 tcgcaatgtc ttcttggaat cagtttcggt attcctgttg taccgccaga taataacaat
     4141 aatcctatgc tcctgtaatc gacatccgga tatttataga aacaatcatt ctcaataagt
     4201 gacgaaaaat ttttatattc ttcactttct ccaagaatat aaatctccaa gttcgtattt
     4261 aattcagatt tcatatcccg aaccatatcc acatatgaaa aacctaaata tttatccttt
     4321 gaaatatatg ctaccgcctc agacttttct ataataccct ttaattcatt ctttcgatgt
     4381 gcaggcaaac tcataatcgg aataattcct gttttaaaca ttgcaaaaga tatcactata
     4441 aattcataac aatttggaag ctgtaataca atcttatctc cttttttaaa acctgcttta
     4501 agtagtccat tagcatactt attcgaaagt ttatcaagct catcataaga taagtttaat
     4561 tctccatcta caatcgctgt tttatcttta tacgtttccg cacagttcgc aacaaactct
     4621 cccaaggtca catgttccca aacattgtca tcataatttt tttctaaatt ttctttcaat
     4681 tctatattca tacttcctcc tatatgcaaa ttgctccaaa atatttcgat gaaatgctga
     4741 atgctatcaa atctttatta ctccttttta ccttatcttc aatttttatt ctctgattgt
     4801 cgatataaat aacttctatt tctttcggat ttcttataag accatatcct tcatatttta
     4861 ggtaggcttc ttttgctgtc caatatctat aaaacattgg tatattactg cctatattct
     4921 taatctctct ggatgtaaag caattttcaa gtatatcttc aaacgcaaag ccatcattca
     4981 ctttttcaat gtctattcca agctctttct ttgaaaaacc aattactaca aatccatccg
     5041 tatgtgaaat attaaatttc actccacttt tattttcaat atatggttta ttatgcttat
     5101 ctctaaaaga aactatattt tcaattggaa cacctaatat catttcaaag actttgttta
     5161 aaagacttct tgaaactgca aaatttattt tcgcaacttc cgacttatat gcatcaagtt
     5221 tttcaatttc ttcttctttc aaaaaatttt tcaaatcttt tatcataaat tcacttgtgt
     5281 tagatgtaac taacaccata tcaaaaaaaa ttagtaacct acttatatca attaaacttc
     5341 gtagttcttt tttatctgaa atttctattc tatatatttt cattggaata aacaaattct
     5401 tcaattgctt ttatcacact ttcaggagat gtatttacaa acatatgctt gccattaata
     5461 tatctgtaag agaattcttt cgtcgtataa tcttgccatt ttaaaagttc ttcaagttcc
     5521 atttcttcat caatatcacc catcagacct aaaatcttgc tattcaattt ttcccctttt
     5581 gtatcctggt agtcctcatc gataataaaa tcggctctta gtgttggtaa aaaaatccca
     5641 atcaaatctt tattgtctaa tatctcattt ggagtaccat catatcttct taacccttca
     5701 ataaatcctt catcatctaa atgataaatc ggattcggtt ccttatagca aggggctcgc
     5761 ccagctgata tgataattcc attcggattt ggtaacccat tttctttaat tttcagagcc
     5821 aattcataag caatcttagt tcccatacta tgcccgaaaa aataataagg tgagttaaaa
     5881 tcaaaagtca tttttaagtc ttcaaacaat ccttttacaa gttcttctat gttgctaatt
     5941 gctttttcag aaaacctgtt ttctctccct ggatactgtg caacgaagag atttatatct
     6001 ttaaattgat taccccatct tctgaatgat gatactccac cacctgcaaa tggaaacaca
     6061 aataaactag ctttcgtgtt ttccatttct ttattaacgt attcgaacca cattcccatc
     6121 aaaacacctt ccatctgatt attaatatac tactagaact attattgtta gatacatcta
     6181 acaataatag tttaatcctt ctaacataaa aagtcaatac atttacactg ttttatagtt
     6241 atattttcta tatctaaaag gcttgaagaa actaagttat atacctttta taattatcaa
     6301 aaaataaaga acatacaatt tt
//
LOCUS       DARYXZ010000077         6302 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYXZ010000077 DARYXZ010000000
VERSION     DARYXZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6302
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            88..237
                     /locus_tag="TV186_001876"
     CDS             88..237
                     /locus_tag="TV186_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533234.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGVRLVETKEFHPVS
                     GTLLD"
     gene            complement(234..434)
                     /locus_tag="TV186_001877"
     CDS             complement(234..434)
                     /locus_tag="TV186_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEL1533235.1"
                     /translation="MQRQYVSSSNVRSVGWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            545..829
                     /locus_tag="TV186_001878"
     CDS             545..829
                     /locus_tag="TV186_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1533236.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVIGMLNNETEIYPLELNKKQIS
                     KMLGVDPKTFDVRFNSHKDFPRIETGGREKYPRDLVIEWYSKNWERTGIR"
     gene            826..972
                     /locus_tag="TV186_001879"
     CDS             826..972
                     /locus_tag="TV186_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533237.1"
                     /translation="MIKKLFNFIFAKPKEESRQPYQQPRGFLDFETGKRIEIDPITRK
                     EYFV"
     gene            1176..1421
                     /locus_tag="TV186_001880"
     CDS             1176..1421
                     /locus_tag="TV186_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1533238.1"
                     /translation="MLLTILSNSDEWRVYPEELAKRCRDSVDAVRTQLKALEKAGYIR
                     SYRKSLGGRYGTETHRFCSDTKISDEVFQELLKELNC"
     gene            1583..1966
                     /locus_tag="TV186_001881"
     CDS             1583..1966
                     /locus_tag="TV186_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1533239.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHQDNMPIDVVNLAL
                     REAVENNKINWKYINKILVEWHKAGDTTIEKVKERLQRFEDSKEQRHATISNVPSWSN
                     PDYQGPTYDDLKVNPSEVSDGAGDF"
     gene            1947..2180
                     /locus_tag="TV186_001882"
     CDS             1947..2180
                     /locus_tag="TV186_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533240.1"
                     /translation="MAQEIFDGFNALINKMYGRQSSIETFNRFVEYCQKRREENGVEP
                     VLNPINLFAFGVGITTEEANKLRIKRYKQENGL"
     gene            2177..2317
                     /locus_tag="TV186_001883"
     CDS             2177..2317
                     /locus_tag="TV186_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533241.1"
                     /translation="MTKQYRETLIWHRASHKEREKLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            2326..2532
                     /locus_tag="TV186_001884"
     CDS             2326..2532
                     /locus_tag="TV186_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533242.1"
                     /translation="MTPEQVEKAKIRAKRELETFSIYLDQAIVEYGSTLSPQEVFLAA
                     GFAYLGAGQTDIHAAIEGLYEQIQ"
     gene            2667..3395
                     /locus_tag="TV186_001885"
                     /pseudo
     CDS             2667..3395
                     /locus_tag="TV186_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017827951.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            3572..4783
                     /locus_tag="TV186_001886"
     CDS             3572..4783
                     /locus_tag="TV186_001886"
                     /inference="COORDINATES: protein motif:HMM:NF018751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEL1533243.1"
                     /translation="MSENLTLFENLNDIKPAEPAELSFDFEFTPAEIKIKGKEKLEEI
                     LAAYAKKYDGYTVTAETFEDDAKVRAKLNTLQKDINNSVKTKLAEYNNPLDDVKQWVN
                     SIIEPIKKITKTIDEGVKHFEEIERQKRANTIKETFEAAIAETGADIDIRLFESNFDD
                     MSAKGYFMADNVRVNTATKKAINKLVAEEVAKKQEHEQALIQISEAAAKADFGPAIYI
                     KRFENGAQLADILQAIADDKLLADKVREEEKRKAELSKRVEEMTALAQREGLQPGKYV
                     KLLEDGKSALVVFETLMDDSKKMQAKIAQKNAEAHQQQIEQTEYMSEASNSGVNELET
                     DKVINNIIKQENALEAKIEPNKSVTKWQGDFKITFPDSETAKLFGGQGGLYEKHGVIV
                     EKLGEWVKIND"
     gene            4776..5612
                     /locus_tag="TV186_001887"
     CDS             4776..5612
                     /locus_tag="TV186_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1533244.1"
                     /translation="MTKLTEENYYQDREWLSNSRFKAFLDCEAKALAVENNEWEDTRD
                     ETPLLVGNYLHSYFESPEAHEKFKAENGAKMISSRGVTKGELKKEYKVAQNMIETLET
                     DEIFNLMYHGQSGDNVLKEMIIYGEILGIKVKGKVDSINLTKGYFCDLKTMKSIHSDE
                     WSNDLRKRVPGVAANIIGFKYHIQMGLYQELLRQMTGKTLQPLIIAISKENVPDKELI
                     ELGQTWLDEGLQLFENNVEHVHEVIIGKAEAKSCGRCDYCRSQKKLNRVVDLDDLIAG
                     IF"
     gene            5797..6138
                     /locus_tag="TV186_001888"
     CDS             5797..6138
                     /locus_tag="TV186_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533245.1"
                     /translation="MEQIKITGTDTILILDRVDRAFVIEGNLAERWRFTSKFIKIDDE
                     LSLDEDGELFEIVYDLMLEAKPHNVINLTSSYFAKEHKKDTDEIIKVFAFIEDNKKNI
                     FETLGIRGVLE"
BASE COUNT         2302 a         1040 c         1370 g         1590 t
ORIGIN      
        1 ggccagcagt attttattaa taaattcctt aatcaggaat atctgccagt ttagaaagga
       61 aacaaaacca acgaaaagga gaaaagtatg ccagaggatt taatcaaaca actagaagct
      121 ggttcagaat ttctagcaaa gacatgttta catagcaaga ttattatcac ggtggatggt
      181 gttcggcttg tggaaacaaa agagttccac ccagtgagcg gaactctact agattagaca
      241 atacgtgtat aagtgtgtat cttagctaat ctatgaatat ttgagccaac agacccaaca
      301 agaacagaac ggtattccgt ttggcttaca ttgtgataat ggtaaataga accattatta
      361 aactcaactt ccaaagtgtt attttcccaa ccaacacttc ggacgttact agatgaaacg
      421 tattgacgtt gcataacttt ttctcctttc cgcgatgata gctttattat agcacgcaag
      481 gagaatacaa aaaaagtccg acgggaatcg gactcgacaa taatatttat gaggtaattt
      541 tatcatggat agtagattat tacaaatgct tgatgagttt gaggcgggtc tgatagaccg
      601 taaaatcaaa gtcataggca tgcttaataa cgaaacggaa atttatccgc tagagcttaa
      661 caaaaagcaa atcagtaaga tgctgggagt tgatcctaaa acatttgacg taagatttaa
      721 tagccacaaa gattttccgc gcatcgaaac gggaggtcgg gaaaaatacc cacgagattt
      781 agttattgag tggtatagca aaaactggga aaggacgggg ataagatgat taaaaaacta
      841 tttaacttta tttttgcaaa gccaaaagaa gaatcaaggc aaccttatca acaaccgaga
      901 ggttttctgg attttgaaac aggtaaacga attgaaatag atccgataac aagaaaggaa
      961 tacttcgtat gatgcatcaa attaatatat cgcttagaaa ttttgtcgag actggagaga
     1021 ttgacaacat cttcgacatt tttagaattt tagatttcta ctttcgggag gtggtcagct
     1081 gatgcagtac atttttcaag acgttgagag ggagttacac gagcgttagt aatgagtttg
     1141 tcaacgataa aaaactttat aacaaggaaa agggattgtt gttgaccatt cttagcaata
     1201 gcgatgagtg gcgagtatat ccggaggaat tggctaaacg ttgcagagat agtgttgacg
     1261 ctgtcagaac tcagctaaaa gcacttgaga aagctggata catcagaagt tatcggaagt
     1321 cgcttggcgg gcgatatggt accgaaaccc atagattttg ctcagacaca aaaataagtg
     1381 atgaggtttt tcaagagctg cttaaagaat taaattgcta atgtgcaaat tgctaatgtg
     1441 caaattgcta atgtgcaaat tgctaatgtg caaattgcta atgtgcaaat tgcctaacta
     1501 ataaatacta acactaaata aatactaaat aataataaat actaacaaac aataagcatc
     1561 atcatcaaca gcaggaggag ctatggacga aaaaaagctt tttgaaaatt ttcaactaac
     1621 tttcggaaga atgatatcgc catttgaaat agaagatatt caaaagtgga ttcaccagga
     1681 taatatgccg attgatgttg ttaaccttgc tttaagagaa gcggtagaaa acaacaagat
     1741 caattggaag tatatcaaca aaattttggt ggagtggcat aaagctggag atacgacgat
     1801 tgagaaggtc aaagagaggt tgcagagatt tgaggatagc aaagaacaac gacatgcaac
     1861 tatctcaaat gttcctagct ggtcaaatcc agactaccaa ggcccgacat acgatgattt
     1921 aaaagtaaat ccaagcgagg tgtcagatgg cgcaggagat ttttgatgga tttaatgcct
     1981 taatcaataa aatgtatggc agacaatcta gcatagagac ctttaaccga tttgtcgagt
     2041 attgtcaaaa aaggagagag gaaaacgggg ttgagcctgt attaaatccg atcaatcttt
     2101 ttgcattcgg cgttggaatc acaacggaag aagctaataa attaagaata aaacgctaca
     2161 aacaggagaa tggattatga caaaacaata tcgagagaca cttatctggc atcgggcaag
     2221 tcacaaagag cgtgagaagc tgcttgattt cgggctagtt gataaatcac agtacatgac
     2281 actattacgc caattgcgca agaaatatgc gatttaggag gaaatatgac accagaacaa
     2341 gtggaaaaag caaaaatcag agctaaacga gaacttgaaa cgtttagcat ctaccttgac
     2401 caggcgattg tcgaatacgg aagtacgcta agtccacaag aagtcttttt agcggcaggg
     2461 tttgcctacc ttggtgcagg tcagactgac atacatgcgg ccatcgaggg gttatatgag
     2521 caaatccaat gattttaatt ttagcgatga ctgggaaagc aactatttcg aggtccaagc
     2581 tttgctaggg caagagatag acaagctcca aaacagggtc atagcgctaa gccaggaaaa
     2641 caatagatta aaagcgagga aatgaaatgg caagtgaaat tgtaacaatt caaaaagata
     2701 tcactgatat cgttaattca aaaattagta tgcttcagaa cgaaggtctt gtaatagcgc
     2761 caaactatgc tccagcaaat gctttgaagt cagcattctt taaaatttta aaaaccaaag
     2821 acagaaataa gaggcctgct cttgaagcct gcacaaagga ctcaattgcg aactcgctcc
     2881 ttgaaatggt cacccaagga ttatcacctg caaaaaatca atgctatttt atcgtttacg
     2941 ggaatgagct ccaactgcaa agatcatatt tcggaacaat ggcagtttta ttgcagcaga
     3001 aaaaaattaa atcaattaag tcagaagtta tttatgaagg tgacgatttt gagcttgaaa
     3061 ttgtagatgg tgaaaagaaa ttcaaaaagc atgatactca ttggaaaaat caagacaatc
     3121 caattgaagg ggcttattgc attattgagg atatagatgg taacactaag ctaacactga
     3181 tgacaaaaaa agagattgat aaagcgtggt ctaagacaaa gactggtgga gggacacaaa
     3241 aagaattccc tcaggaaatg gccaaaaaaa cagttatcaa cagagctgct aagtttttta
     3301 tcaatatcag tgatgacagt gacattttgg cagattctat taacaagacc accgcagatg
     3361 aatatattga cgatcgtcaa gtaaaagatg taacggaaac acagtcacct gcacagacac
     3421 tactcgataa catgaagcat gacgaggaaa tgagcaaaat cgaaacgatg caaaatgaac
     3481 aattgatgca tgatccagaa acaggagaaa tcattgatgc agaggttgtt gaggcggacc
     3541 taaaggaatc tgatatggag gagccattct aatgagcgaa aatttaacac tttttgaaaa
     3601 tttaaatgac attaaaccag ccgaacccgc tgagctgagt tttgattttg agtttactcc
     3661 agccgaaatc aaaatcaaag ggaaagagaa gctcgaagag attttagcag cctacgctaa
     3721 aaaatacgat ggctacacag tgacagccga aacctttgaa gacgatgcaa aggttagagc
     3781 aaaactcaat actttgcaga aagatattaa taactctgta aaaacaaaac tcgcagaata
     3841 caataaccct cttgatgatg ttaagcagtg ggttaactca attattgagc caattaaaaa
     3901 aattacaaaa acgattgatg agggtgttaa acactttgaa gaaatcgaac gtcagaagcg
     3961 tgcaaataca atcaaagaaa cctttgaggc tgctattgct gaaacaggtg ctgatattga
     4021 tatccgcttg ttcgaatcta actttgacga tatgtcggct aaaggatatt ttatggctga
     4081 caacgtccgc gtcaataccg ctaccaaaaa ggccattaac aaattggttg ctgaagaagt
     4141 agcaaaaaaa caggaacatg agcaggcgct tatccaaatt tcagaagctg ctgccaaagc
     4201 ggattttgga ccagctatct atatcaaacg atttgaaaat ggcgcacaac tggcagatat
     4261 cttacaagca atcgctgacg ataaactgct tgctgacaag gtgcgcgaag aagaaaaacg
     4321 caaagcagaa ctatctaagc gagtagaaga aatgacagcc ctggcacaac gtgaagggtt
     4381 gcaaccaggc aaatatgtaa aattgcttga agatggcaag tctgctttag tcgtttttga
     4441 aactctgatg gacgattcta aaaaaatgca ggccaagata gcacaaaaaa acgcagaagc
     4501 gcatcagcaa caaatagaac agaccgaata tatgtctgag gcctcaaatt cgggggtaaa
     4561 cgagcttgaa acagacaagg tgataaataa tatcatcaaa caagaaaatg ccttagaagc
     4621 caaaatagaa ccgaataaga gcgtcacaaa atggcaaggt gattttaaaa taactttccc
     4681 ggattcagaa acagctaaac tatttggcgg gcaaggcgga ttatacgaaa agcatggcgt
     4741 gattgttgaa aaattaggtg aatgggtgaa gattaatgac taaattaacc gaagaaaatt
     4801 attatcaaga ccgagaatgg ttgtctaact caagatttaa ggctttcctt gattgtgagg
     4861 ctaaagcttt agctgtcgaa aacaacgagt gggaagatac cagagatgag acaccgcttt
     4921 tggttggtaa ctaccttcac agctatttcg aaagtcctga agctcatgag aaattcaaag
     4981 ccgagaatgg agctaagatg atttccagtc gtggagttac aaaaggggaa ctcaaaaaag
     5041 agtacaaagt agcgcaaaac atgattgaaa cgctagaaac tgatgagata tttaatctca
     5101 tgtaccatgg ccaatctggt gataatgttt tgaaagaaat gatcatatac ggggaaatct
     5161 taggcataaa agttaaagga aaagttgatt caatcaattt aacaaaaggt tatttttgtg
     5221 acttaaaaac gatgaaaagc atacacagcg acgaatggag taatgacttg cgtaagcgtg
     5281 tacctggtgt agcagctaac attatcgggt ttaaatacca tatccagatg gggctctatc
     5341 aagaattact cagacagatg actggaaaaa cgcttcaacc gctaatcatt gcaatcagta
     5401 aagagaatgt accagataag gaactcatcg aacttggcca aacgtggcta gatgaagggt
     5461 tgcaactttt tgaaaacaat gtggagcatg tgcacgaagt catcattggt aaagctgaag
     5521 ctaagtcgtg tggacgttgt gattattgtc gaagtcagaa aaagcttaat agggtggttg
     5581 atctcgatga tttgattgca ggaatttttt aggagatctt attgtattgc aaagtgatgc
     5641 tcggcctttg cagcaacaaa tattttccga gcgagaaagg aaaattgcaa tatcgtcaag
     5701 ttaacaggat tgatgatata aagagttgct acactcgtcc ttgctaatgc tcacacacaa
     5761 ttttagggcg agtgtggatt ttaaaaaggt gaaaatatgg aacaaatcaa aattacagga
     5821 actgacacaa tattaatttt agatagagta gatagggcct ttgtcattga gggtaatcta
     5881 gctgaaagat ggcgttttac tagcaagttt ataaagattg acgatgagct atcgctggac
     5941 gaggacggcg aattgtttga gatagtttat gacttaatgc tagaagcaaa acctcacaac
     6001 gtgattaatc taacatcatc atattttgct aaagaacata agaaagacac agatgaaatc
     6061 ataaaagtat ttgcttttat cgaagataac aagaagaata tttttgaaac ccttggcatt
     6121 cgcggggtgc ttgaatgagc aatctagtat tatcgctaga catctcaaca tctggtacag
     6181 gttgggcctt atttaaaggc tcagacctta tccagagcgg tgtcttaaaa cataagagcg
     6241 actcttattt tgaacgtgga cgctatatgg ctagcaaatt aaggttgatc cagtcacgag
     6301 ca
//
LOCUS       DARYXZ010000078         6155 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYXZ010000078 DARYXZ010000000
VERSION     DARYXZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6155
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(1017..1328)
                     /locus_tag="TV186_001889"
     CDS             complement(1017..1328)
                     /locus_tag="TV186_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL1533246.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
     gene            complement(1578..2111)
                     /locus_tag="TV186_001890"
     CDS             complement(1578..2111)
                     /locus_tag="TV186_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL1533247.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            complement(2344..3120)
                     /gene="recX"
                     /locus_tag="TV186_001891"
     CDS             complement(2344..3120)
                     /gene="recX"
                     /locus_tag="TV186_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL1533248.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            complement(3269..4435)
                     /locus_tag="TV186_001892"
     CDS             complement(3269..4435)
                     /locus_tag="TV186_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEL1533249.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWEIYVDNRLKAGVWSPDTYVERTNIFK
                     NHIGPKFGNKKMNAINRIEYENYINNLLNTNSRSTVKHIYDVFSIMLNHAVKNKMLDD
                     NIIKFIDIGDSEIKPINKRRSMQEFKAWDKIARKMLDDYDYAMVRITYLGLRRSEVAG
                     IKLGNITFNDKDCAVVKIDESRTRGRKDGGGLKTAYSERYVYLDFETSQLLKKAIDTS
                     IKIAVCNDRILNKADFLFLGDDEKVKPSFVGKPIGSHYIYCLFKKINKNCDVNFTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSNNYMTSQYTHIKDEVSENVTAAFMGSIK"
     gene            complement(4639..5181)
                     /locus_tag="TV186_001893"
     CDS             complement(4639..5181)
                     /locus_tag="TV186_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HEL1533250.1"
                     /translation="MNLDTVLQQMKECGAYDTWGTKKEVKALPEILSDDEIIQYATSG
                     FVNGNTVLVVLTQKRILFIDKGMLYGIRSTEIPLDMVNSVSYSKGLILGAIAVMNGAT
                     KIEISNIAKDTCPVLTEKIKDCVEQYKYNLYQHQSPQKTATVGSEDAVAEIRKFKKLY
                     DEGILTEEEFIAKKKIILGI"
     gene            complement(5207..5992)
                     /locus_tag="TV186_001894"
     CDS             complement(5207..5992)
                     /locus_tag="TV186_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1533251.1"
                     /translation="MNDKELALYIGSKIKELRKNKGLTQKELAILVNMGDTTIANYEK
                     GFRTPKKNTLFKLANALSVTIDELFPPINKKNKENIVHLKQQSNTTEINNKVALLDKE
                     LKEPRHSYWVKYGENLLSEQNTVGHSKNTVEEPQAAYYTYNYYDHAASAGTGQYLSDV
                     QVETIELPVDYDADFVIPVYGDSMEPEYHSGDYVFVKLSVELTDGDIGVFEYYGDAYI
                     KQLLINDEGAFLHSLNSKYEDIPVDRDSDFRIIGEVVGSYSEK"
BASE COUNT         1721 a         1083 c         1150 g         2201 t
ORIGIN      
        1 ctaacgtcta aagaggacca gattggtgct cttttttgtg atgttaaaac caaaaggagt
       61 ttgagcaagg ctcactttag aactggcttt ccactgaaag cagtgttttt tgagttgaag
      121 cagtgttgga aagctttggc aatcgaagat agggatttta gaggcttttt ggaagtcttg
      181 tttgctcatg tttcctttgt agtgagggca taagagaact gaataatcaa gcttaggatt
      241 gataacgatg tgggggtgag cttttagaac agtcaacggt tggatattgt tttttaaatg
      301 ctgagtaatg cttaaggtgt tcctatgagt ctttctaatg atggtttgat tgcatttcat
      361 gataagtcat atgggcttgt ttttgtacaa ttaaaaaaac tataatttcc acagtgggct
      421 taccgactac agagattata gagctttttg agggagggca aagtttttgt actttaaagt
      481 gtgtttgttg atttttaggt tctataagtt ttgtgcagtt aaaactactt ttaagattac
      541 ggggtatgtg aagatcctat gtgaggctaa cacaaagcaa ttagcttcct actagccatt
      601 tggtcatata gaatttaatc gttatgacaa tgatgccaat tgtcataaag cctatagtga
      661 ttgtcgtaaa atgagatgat aacatatcaa aatgtcagac cctatagata tagctcaata
      721 tgatgggact attgggatgt tctatcaaga tttccatttc ccagaatagg aaatagggct
      781 taggtgatgt gtttgcttag caatgattta cagaatgaaa aaactgtcaa gctcatgtta
      841 ggactatttc taccggcatg agcttagttt attgctatgt atctggctga ctgaatatct
      901 atacagcatt cagagctagg ataaagacac aagattatct catgttggtg cttgtagcag
      961 atgtgatgag ctacaactga atggtaagga ctttatagct gatgtccgag gtcttatcaa
     1021 tacatctcgt gaggcaataa aatcgtttca attccttgct ggtttacgat atagagcgtt
     1081 ttggggtaaa aggcgttaaa tggtgtgtta tagtcaaaaa caatccgaag cccagcttgt
     1141 tgatcaatgt actcataaga aaggtttttt ttatttttaa ttagcctgaa ggtgagaaca
     1201 gtattgaggg gaaacacccc ttttaggtaa tggtcaatga tttcccagaa ggtatcaatc
     1261 agctcaggtg gaaggctgac tgcaacgcca aagcttgcgt atcgtccttt tgttgcttga
     1321 aatgccattg tcaatccttt ctattgttat ggtgttataa tgaggtcatt tgaatgcctg
     1381 atctagctag gcagctgatg ataaatactg attgctactt ggtgttatag gctgtctgtg
     1441 cttgtgccaa gctatagtgg ttaatgatat gaatttgaca acaaatgctg atagattgca
     1501 agtgccagtc cagtttacag ctgtgatact atactagcga ttaaataaag caccctcggt
     1561 ggagtgctag acaacgacta acgattcttc agttcaagat aacgtttgta ccaaatactg
     1621 acataggctt ttgaaaatgg tcctttttct ttattgatcc agtcgactaa tagcttgaca
     1681 ttctctttta aaataaaatc cagattaggt gaataatgca tttcttgctt gtgcatttca
     1741 tattcgtcta catcaagcaa tctcttttca ccatctgcaa agactttgac atcaagatca
     1801 tagtcaatat acttgagcgc ttctgcgtcc atcaggtatg gacttgcaag gttgcaataa
     1861 taggaaacac cattatctcg aatcattgct ataatattga accagtattt tttatgaaaa
     1921 taaacaatcg caggctctcg tgtcacccat cgcctgccgt cgctttcagt aacaagtgtg
     1981 tgatcattaa ctccaatcag agcattttca gttgttttta gtaccatagt atcgcgccag
     2041 gttcggtgca atctaccatc atgcttataa ctttgaattg taataaagtc gccttcttta
     2101 ggtaatttca tgccttacca actttctaca attaaactta tcctctatag tttaccataa
     2161 ttgagaaaat aaatcactgt tttggacaat atgatctgac aaatgcttaa agaagttttt
     2221 agaaatctga tgttcagttg aggagctagc taaaccatta tcaaagctac aggatcataa
     2281 taggactact ttgttgctga ctaaaagctt ttgcgtcaaa tcggtgcagc agccttggta
     2341 gaattagaaa tagtcattta gcttagtggt aatatcatca ctgtcatagc ccttgcggta
     2401 aagggcttgg taaagctttt gcttcaactg atagccatca tagcgacgac tgtattttcg
     2461 taatagcttg tcgaattcct gatcaagcag gtcttcgatg tgctgactat cctgctcaag
     2521 gcttagttga ctgacaatgc ctttggcaag gtcataggaa aagcccttgt taagaagtcc
     2581 ttgtatgatt ttatcggtca aggccttact tggcaatttg tgttgatatt tctggtagat
     2641 tttttcagca gccttttgtg ctatagagga aaaatcagtc tgtgctagga caggctcaat
     2701 gagttgtgag gctattccct tgagcattag cttttgcttg agaagtaatg gtcccttgtc
     2761 tccagtaagg ctattttggc gtatataggt gtcaacgtat tgctgatcat caatccattt
     2821 gccttgtttt aggctatcaa taatgcttgg aatgagatca ggactaatct gatgctttag
     2881 caggtaatct tggacttgct tttggctcct ttgttggaag gcaataaaac ctaaggcctt
     2941 gcttttacca tatgagaatt gtgcgaagct tttgatgtcc tcccattgtt ggctgtctat
     3001 gaccatgtgc ttacttagca taaatgtgac aatcgtatct tctgtgaccg ttaggctatc
     3061 accattgtct agcttaatga ggtataaatg ctttttcttt tcaatttgac tgattttcat
     3121 accctcatta taatgtttta aaatttatat acaagcaaat tgttttaaaa cgttgatatt
     3181 acagcatttt agtttttttc gtttagtcat aaaaagtaac aaaaatcata aaaagtaata
     3241 ttttgtcggg gactatgtcg gggaattttt attttatact gcccataaaa gctgctgtga
     3301 cattttcact tacctcgtct tttatgtggg tgtattggct agtcatgtaa ttatttgaat
     3361 gacctaaagc cgctgccata tgctcaattg ggacaccggc tatttggccc tgtgtagcga
     3421 aaaaatgcct catcatgtgc ggagtaaaat taacgtcgca atttttattg atttttttaa
     3481 ataagcagta gatgtagtgg ctaccgattg gttttcctac aaaagatggc tttacttttt
     3541 cgtcgtctcc taaaaatagg aaatcagcct tgtttaagat gcgatcgttg cacacggcta
     3601 ttttgataga tgtatcaatg gcttttttta gcagttgtga tgtctcgaaa tctaaataca
     3661 catatcgttc cgaataagct gtctttaggc ctccgccatc ttttctacct ctggtccttg
     3721 attcgtctat ctttacgact gcacaatctt tatcattaaa agttatattc cctaatttta
     3781 tgccagctac ctcgcttcta cgcaatccaa gatatgttat cctaaccatt gcgtagtcat
     3841 aatcatcaag catttttctg gcaattttat cccaagcttt aaactcttgc attgatctac
     3901 gtttgttgat aggttttatt tcgctatcgc caatgtcaat aaatttgatg atattatcgt
     3961 ctagcatttt atttttgaca gcatgattta acataatact aaaaacatca tatatgtgct
     4021 ttactgtact tcttgagttg gtattgagca gattgttaat gtagttttcg tattctatac
     4081 ggtttatagc attcattttt ttattgccaa actttgggcc gatgtgattt ttaaagatat
     4141 tagtgcgctc aacgtatgtg tcaggagacc acactccagc ttttaatcta ttatcaacgt
     4201 atatttccca gtactgatca actgtcaaat ttttgttata agcaaaatca ttgttttcta
     4261 ttttttgctc aatttcagta agtgcagctc tggcttcctg tagcgttttt aagttgcttt
     4321 ttgtagcctc tttcttttta ccttttaagt aataacccct acggacgtag tagcgtttac
     4381 ctttctttgt atcgtaggta aagatatttg ggtattttgt tttgttgtat ttcattctta
     4441 aatcctttcg tttttttgac ttttggacga ggtcgtttga aaggatattg gcatcaccac
     4501 ctttgtgtga tataatttta ggtacaagaa aacgaccttt ttaatggttg tttcttatac
     4561 ggtttcgcct cacgctcaga ctcgccaaag tttgagagcg tggggctttt tttatttttt
     4621 aacggttaac tttacacctt aaattcctaa aattattttt ttcttagcta taaactcttc
     4681 ctctgtaaga atgccttcat cataaagttt tttaaactta cggatttcag caacggcatc
     4741 ttccgagcct acagttgctg ttttctgagg cgattgatgt tggtacagat tatatttgta
     4801 ttgttctaca caatctttta ttttttcggt aagtacaggg caagtgtcct tggcaatatt
     4861 agatatttca atttttgtgg ctccgttcat aacagctatt gcgccaagaa ttaaaccttt
     4921 agagtatgag acgctattaa ccatatcaag aggaatttct gtcgatctaa ttccatataa
     4981 cattccctta tcgataaata aaattcgttt ttgggtcaat acaacaagga cagtattgcc
     5041 gtttacaaac ccagatgttg cgtattggat aatttcgtca tctgacaaaa tttctggcaa
     5101 agcctttact tctttctttg tcccccaagt gtcgtaagcc ccacattcct tcatttgttg
     5161 caaaacagta tctaaattca taataaaact ccttataaaa atattcttat ttttcagaat
     5221 aactccccac aacttcacca ataattctaa agtcgctatc tctatctacg ggtatatctt
     5281 catacttgct atttaaactg tgcagaaatg ccccctcgtc atttataagt agctgtttga
     5341 tataagcgtc accataatac tcaaaaacgc ctatatcgcc atctgttagc tctacggata
     5401 gcttaacaaa gacatagtcc ccagagtgat attcgggttc catggaatct ccataaacag
     5461 gaataacaaa atcagcgtca taatcaactg gtaattcaat tgtttctact tgcacatcac
     5521 ttaaatattg accagtacca gcagaagcag cgtggtcgta gtagttgtag gtgtagtagg
     5581 cggcttgtgg ttcttctact gtattcttac tgtgtcctac tgtgttttgt tcagataaaa
     5641 gattttcacc gtattttacc caataactat gacgaggttc tttgagctct ttgtctaata
     5701 aagcgacttt gttattaatt tctgtggtgt tagattgctg tttaagatgt acgatatttt
     5761 ctttattttt tttatttata ggagggaaga gttcatctat agtaacagat agggcattcg
     5821 caagtttaaa caaagtattt tttttaggcg ttctaaaccc cttttcatag ttagcaattg
     5881 tagtatcccc catattaacc aagattgcta actctttttg agttagccct ttattttttc
     5941 tcagttcctt gattttagag ccgatatata aagctagctc tttatcattc atttgaattc
     6001 ttctttcttt ttatttaata atagtataac acataaattc acgttttgaa aagttttttt
     6061 gttttttcga aaaaaaacag ttgacacttc acgaaaagtg aagtacaata taatcaagct
     6121 taaggaatta agcaaaataa aaactcccaa gaggg
//
LOCUS       DARYXZ010000079         5634 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYXZ010000079 DARYXZ010000000
VERSION     DARYXZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5634
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TV186_001895"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TV186_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL1533252.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TV186_001896"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TV186_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
BASE COUNT         1610 a         1261 c         1066 g         1697 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt gctctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc attt
//
LOCUS       DARYXZ010000080         5468 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYXZ010000080 DARYXZ010000000
VERSION     DARYXZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5468
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            227..1780
                     /locus_tag="TV186_001897"
     rRNA            227..1780
                     /locus_tag="TV186_001897"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2002..2074
                     /locus_tag="TV186_001898"
     tRNA            2002..2074
                     /locus_tag="TV186_001898"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2035..2037,aa:Ala,seq:tgc)
     gene            2382..5281
                     /locus_tag="TV186_001899"
     rRNA            2382..5281
                     /locus_tag="TV186_001899"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5366..>5468
                     /gene="rrf"
                     /locus_tag="TV186_001900"
     rRNA            5366..>5468
                     /gene="rrf"
                     /locus_tag="TV186_001900"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1577 a         1102 c         1576 g         1213 t
ORIGIN      
        1 tcgtatacta gtgaagctgt cggcgagcac tagctcaagt taatgaaaaa aaggtaaaaa
       61 aagtagttga caaaggcagt ctaagctgat agaatgtaat agttgtctcg tgagacaaag
      121 acctttgaga actgaataag acgacctaaa cgtgcgggtt acggaagtaa cctgtcaata
      181 aagaaacaag tcagtaatga cgtcgagtta agagctcaaa cactgaatta acgagagttt
      241 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtgg aacgcacaga
      301 tgatacgtag cttgctacaa ttatctgtga gtcgcgaacg ggtgagtaac gcgtaggtaa
      361 cctagcttat agcgggggat aactattgga aacgatagct aataccgcat aaaagtggtt
      421 gacccatgtt aaccatttaa aaggagcaac agctccacta tgagatggac ctgcgttgta
      481 ttagctagtt ggtagggtaa aggcctacca aggcgacgat acatagccga cctgagaggg
      541 tgaacggcca cactgggact gagacacggc ccagactcct acgggaggca gcagtaggga
      601 atcttcggca atggggggaa ccctgaccga gcaacgccgc gtgagtgaag aaggttttcg
      661 gatcgtaaag ctctgttgtt agagaagaac agtgatggga gtggaaagtc catcatgtga
      721 cggtaactaa ccagaaaggg acggctaact acgtgccagc agccgcggta atacgtaggt
      781 cccgagcgtt gtccggattt attgggcgta aagcgagcgc aggcggtttg ataagtctga
      841 agttaaaggc agtggcttaa ccattgtatg ctttggaaac tgttaaactt gagtgcagaa
      901 ggggagagtg gaattccatg tgtagcggtg aaatgcgtag atatatggag gaacaccggt
      961 ggcgaaagcg gctctctggt ctgtaactga cgctgaggct cgaaagcgtg gggagcaaac
     1021 aggattagat accctggtag tccacgccgt aaacgctgag tgctaggtgt taggcccttt
     1081 ccggggctta gtgccggagc taacgcatta agcactccgc ctggggagta cgaccgcaag
     1141 gttgaaactc aaaggaattg acgggggccc gcacaagcgg tggagcatgt ggtttaattc
     1201 gaagcaacgc gaagaacctt accaggtctt gacatcccga tgctattctt agagataaga
     1261 agttacttcg gtacattgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga
     1321 tgttgggtta agtcccgcaa cgagcgcaac ccttattgtt agttgccatc attaagttgg
     1381 gcactctagc gagactgccg gtaataaacc ggaggaaggt ggggatgacg tcaaatcatc
     1441 atgcccctta tgacctgggc tacacacgtg ctacaatggt tggtacaacg agtcgcaagc
     1501 cggtgacggc aagctaatct ctgaaagcca atctcagttc ggattgtagg ctgcaactcg
     1561 cctacatgaa gtcggaatcg ctagtaatcg cggatcagca cgccgcggtg aatacgttcc
     1621 cgggccttgt acacaccgcc cgtcacacca cgagagtttg taacacccga agtcggtgag
     1681 gtaaccgtta aggagccagc cgcctaaggt gggatagatg attggggtga agtcgtaaca
     1741 aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggaaaa aggaagcacg
     1801 tttagcgtct tatttagttt tgagaggtct tgaaataagt catgagaacg ttaagaaacc
     1861 cgtatgacaa tagggaactg acgcagagtc gtaggactca aggaagtgat tctttttcac
     1921 tagggtttta gttcgaatac agtttggctt catacagacc attgataaga gtatacatat
     1981 acaagtacat ttatagtgta cggggcctta gctcagctgg gagagcgcct gctttgcacg
     2041 caggaggtca gcggttcgat cccgctaggc tccattatct aggatacaaa gagaagtttg
     2101 ggttacctaa ttttctgtat tctaagatat ataagatata gttcaagtaa ttgaacacga
     2161 cctcattttt taggaaaaaa gataaatctc ctcgtgtgta aagcacacat cgtcgatttc
     2221 ctatttttct acaaaaatgc ccaacaagtt gggacggtct tagtatctta atcttgtcca
     2281 ttgaaaattg aataactata tcatattccg caatcaaaaa agattgtaag aaagtaacaa
     2341 gaaataaacc gaaacgctgt gataacgagt ttaaaaaata aggttaagtt aataagggcg
     2401 cacggtggat gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt
     2461 ggggagctgt aagtaagcaa agatccagag atgtccgaat gggggaaccc actagctaat
     2521 ggctagtatc cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta
     2581 agtagctgca ggaagagaaa gcaaacgcga ttgcctgagt agcggcgagc gaaaaggcag
     2641 gagggcaaac cgaagagttt actcttcggg gttgtaggac tgcgctgtgg gacgacaaga
     2701 ttatagaaga aggccttggg aagggtcgcc aaagagagta atagcctcgt attcgaaata
     2761 gtctttaacc ctagcagtat cctgagtacg gcgagacacg aggaatctcg tcggaatctg
     2821 ggaggaccat ctcctaaccc taaatactca ctagtgaccg atagtgaacc agtaccgtga
     2881 gggaaaggtg aaaagcaccc cgggagggga gtgaaagaga acctgaaacc gtgtgcctac
     2941 aagaagttcg agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt
     3001 acgtttatgt gcgaggttaa gttgaagaga cggagccgaa gggaaaccga gtcttaatag
     3061 ggcgtaagta cgtggacgta gacccgaaac catgtgacct acccatgagc aggttgaagg
     3121 tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg
     3181 tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt
     3241 agggctagcg tcgatatgaa gtctcttgga ggtagagcac tgtttgggtg aggggtccat
     3301 cccggattac caatctcaga taaactccga atgccaatga gatatgatcg gcagtcagac
     3361 tgcgagtgct aagatccgta gtcgaaaggg aaacagccca gaccaccagc taaggtcccc
     3421 aaataactgt taagtggaaa aggatgtggg gttgcacaga caactaggat gttagcttag
     3481 aagcagctat tcattcaaag agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa
     3541 aatgtaccgg ggctaaaaca gtttaccgaa gctgtggatt accgttaagg taatggtagg
     3601 agagcgttct atgtgtgatg aaggtatact gtgaagagtg ctggaacgca tagaagtgag
     3661 aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggatt
     3721 ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc gaagggtgta
     3781 tccgatggac aacaggttga tattcctgta ctagagtata tagtgatgga gggacgcagt
     3841 aggctaacta aaccggacga ctggaagagt ccggctaagc agtgaggtgt gatgtgagtc
     3901 aaatgcttac atctataaca ttgagctgtg aaggggagcg aagttaagta gcgaagttag
     3961 agacgtcaca ctgccaagaa aagcttctag cgatacgtat actctacccg taccgcaaac
     4021 cgacacaggt agtcgaggcg agtagcctca ggtgatcgag agaactctcg ttaaggaact
     4081 cggcaaaatg gccccgtaac ttcgggagaa ggggcgctga ctgaaggtca gccgcagtga
     4141 ataggcccaa gcaactgttt atcaaaaaca cagctctctg ctaaatcgta agatgatgta
     4201 tagggggtga cgcctgcccg gtgctggaag gttaagagga gtgcttagcg caagcgaagg
     4261 tatgaattga agccccagta aacggcggcc gtaactataa cggtcctaag gtagcgaaat
     4321 tccttgtcgg gtaagttccg acccgcacga aaggcgtaat gatttgggca ctgtctcaac
     4381 gagagactcg gtgaaatttt agtacctgtg aagatgcagg ttacccgcga caggacggaa
     4441 agaccccatg gagctttact gcagtttgat attgagtatc tgtaccacat gtacaggata
     4501 ggtaggagcc atagaagtcg ggacgccagt ttcgatggag gcgatgttgg gatactaccc
     4561 ttgtgttatg gctactctaa cccggatagg tgatccctat cggagacagt gtctgacggg
     4621 cagtttgact ggggcggtcg cctcctaaaa tgtaacggag gcgcccaaag gttccctcag
     4681 attggttgga aatcaatcgc agagtgtaaa ggtataaggg agcttgactg cgagagcaac
     4741 acctcgagca gggacgaaag tcgggcttag tgatccggtg gtaccgtatg gaagggccat
     4801 cgctcaacgg ataaaagcta ccctggggat aacaggctta tctcccccaa gagttcacat
     4861 cgacggggag gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc
     4921 caagggttgg gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag
     4981 acagttcggt ccctatccgt cgcgggcgta ggaaatttga gaggatctgc tcctagtacg
     5041 agaggaccag agtggactta ccgctggtgt accagttgtc tcgccagagg catagctggg
     5101 tagctatgta gggaagggat aagcgctgaa agcatctaag tgcgaagccc tcctcaagat
     5161 gagatttccc ataacgttaa gttagtaaga gccctgagag atgatcaggt agataggtta
     5221 ggagtggacg tgtggtgaca catggagcgg actaatacta atagctcgag gacttatcca
     5281 aaagatgaaa ccagtcgcta ttgacagctt aaggaattct tgttagacta tagttattca
     5341 attttgagtg gagaagactc gtaagttaag tgacgatagc ctaggagata cacctgtacc
     5401 catgccgaac acagtagtta agccctagaa cgcctgaagt agttgggggt tgccccctgt
     5461 gagatacg
//
LOCUS       DARYXZ010000081         5325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYXZ010000081 DARYXZ010000000
VERSION     DARYXZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(150..389)
                     /locus_tag="TV186_001901"
     CDS             complement(150..389)
                     /locus_tag="TV186_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL1533253.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TV186_001902"
     CDS             complement(548..1036)
                     /locus_tag="TV186_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1533254.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TV186_001903"
     CDS             complement(1055..1345)
                     /locus_tag="TV186_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL1533255.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TV186_001904"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TV186_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL1533256.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5325
                     /locus_tag="TV186_001905"
     CDS             4640..>5325
                     /locus_tag="TV186_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL1533257.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDT"
BASE COUNT         1622 a         1165 c         1062 g         1476 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatac
//
LOCUS       DARYXZ010000082         5092 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYXZ010000082 DARYXZ010000000
VERSION     DARYXZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5092
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            432..635
                     /locus_tag="TV186_001906"
     CDS             432..635
                     /locus_tag="TV186_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL1533258.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            805..1266
                     /locus_tag="TV186_001907"
     CDS             805..1266
                     /locus_tag="TV186_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL1533259.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            1266..3707
                     /locus_tag="TV186_001908"
     CDS             1266..3707
                     /locus_tag="TV186_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1533260.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(4055..4141)
                     /locus_tag="TV186_001909"
     CDS             complement(4055..4141)
                     /locus_tag="TV186_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1533261.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            4480..4914
                     /locus_tag="TV186_001910"
     CDS             4480..4914
                     /locus_tag="TV186_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533262.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKITEEQQKKDLETSIAKL
                     LVHDYEGVKTIKFQGWGHSRETGSWGTTVIINESNQMSFSFSSIKTLEDIGSTRYNPN
                     TFKLVEKPETDSKPRIMDRMNEINATSLAGVTVIYSNNNQED"
BASE COUNT         1540 a          878 c         1179 g         1495 t
ORIGIN      
        1 gatgacggat atataacagg agacacagta gcgattgtgc gtaaaaacgg acagatattt
       61 gattatgtgt tgccagggga gaaagtgcag ccttgggaag tggtgaccga ggaaaaagta
      121 gaaaatgtgc tgagggagtt agattggcgg tcggtcaaaa gtcggtcaaa gttactctaa
      181 agcactgata tcaatgcatc taaaatccgt ctaccgcctt agattgttaa agcaaggtca
      241 gcatgacttt gcttttttac attttagcag gtggagtaga aaagctgtca ttgtgagggg
      301 tatgtgttga cagtggctgc cattcgtgtt acactgagcg agtaaattag tttttgaatt
      361 agtagttgtg ttttggcatc tttatttctc tctatgttta caaatgcgtt atagaaagga
      421 agtggatgac tatggcacaa ggtacagtca agtggtttaa tgctgaaaag ggctttggct
      481 ttatttcaac tgaaaatggt caagatgttt ttgcacattt ttcagcaatc cagtctgacg
      541 gctttagatc gttagacgag ggacaaaggg tgacgtttga tgttgaagac ggacagcgcg
      601 gtcctcaggc agtaaatatc actaaattgt cttaatctag tgagcagata ataggggatg
      661 ggtgttgttg atagcacctg tccttttaca ttctagtgat ttccatttgc ttttagtgac
      721 tgctatttga tataatgtta gtcagtttta gtcaaataaa ggcttaaagc agcaaatgaa
      781 tcgttttagc aaaggagtga cggcatgcca acaaaaaata cttccgatag tatcgaagaa
      841 tatatcaaag aattgttagc ccaatcagga atcgcagaga tcaagcgctc catgctggcg
      901 gattcctttc aagtagtacc aagccagatt aattatgtga tcaagacccg ttttacagaa
      961 agcagaggct atgaggtaga aagtaagcgt ggtggtggtg gctacattcg tattgctaag
     1021 gttcattttt cggataagca ccacctgatt ggtacgttga tcgcttctat tgatgattgt
     1081 ttaagcgagc aggcctttac agattcgatt cagctgcttt ttgatgagca actgttaaca
     1141 gagcgcgaag gaaacattat cttagctgta gcttctaatg atgttttggg acatcaagca
     1201 ccagaaattc gtgctcgtat gctttatcgc ctattgcaac gaattgatag aaagggaagc
     1261 aattagtgat gatttattca ttaaagatgc aagacatttt taatcaggct caatttcaag
     1321 cagagcgctt tgatagtcct taccttgaga cctggcatat tttattagct atggtagctg
     1381 ttgaccattc cttagcggcc atggtgttaa gcgaatttga acgaaagatt agggctgaag
     1441 agtatgaggc tgctgctatt ttagccatgg gaaaaagtcc caaagaggtg acttctgtcc
     1501 aattcaagcc acaatccaag gccttatcag aaatactagc atttgctcat gctatctgtc
     1561 aggttatcaa tgagcatgag gttggctcag agcatgtact ctttgctatt ttgctcaatc
     1621 cggatattat ggccagtcgt ctgttagaat tggcaggcta caggctcaag gattctggca
     1681 agggagagcc taggtttgcg gatttacgta aggctattga gctaaatgcc ggctatagca
     1741 aggaaactat taaggcgatt catgagttgc gtaagcctaa aaagagtaaa tcagtaggca
     1801 ccttttctga aatgatgaag ccacagagta cagctggtga gctatcagac tttacaagag
     1861 acctgacaga gatggcaaga cagggcttat tagagccagt catcggacga gaaaaagagg
     1921 tgtcacgtat ggttcaggtg ctttgtcgta agacgaaaaa taatcctgtt cttgttggtg
     1981 atgcgggtgt cggaaaaact gctctagctt atggcttagc gcagcgaatt gctaatggag
     2041 ccattcctta tgaattacaa gacatgcgtg tcttggagct tgacatgatg agtgtggttg
     2101 caggtacccg ttttcgtggg gattttgaag agcgcatgaa tcaactcatt gacgatattg
     2161 aagcagatgg taagatcatt ttgtttgtcg atgagctaca taccattatg ggatcaggaa
     2221 gtggtattga cagcacactt gatgccgcta atattctaaa gccagccctt tctcgcggta
     2281 ccctgcatat ggttggcgct acaactcaag aggaatatca aaagcacatt gaaaaggacg
     2341 cagccctttc tcgtcgcttt gccaagatat tgattgagga gcctagtgtt gaggacgctt
     2401 atcagatttt gcttggcttg aagccttcct atgaacagta ccataatgta acaatctctg
     2461 atacagctgt ccatactgct gtgaagctgg ctcggcgcta tttgacaagt aagcagcttc
     2521 cagactcagc gattgatctg cttgatgaag ccagtgcgat ggtgcaaagt atggttaaaa
     2581 agacgcagcc tgactttata acaccgcttg atcaagccct gcttgatggt gatatgagca
     2641 aggtgtcagc ccttttagtc aaagaggata agcaaccaaa gctaaaacca acagcagtta
     2701 ctgaagatga tatgttacac accttaagca agctatcagg tattccccta gaaaaactaa
     2761 ctcaggcgga tagtaaaaaa tacctgaatc tggaaaagga attgcataag cgtgttgttg
     2821 gtcaggaaat ggctgtttct gctattgcac gagccattcg tcgtaaccag tcaggcattc
     2881 gcacaggcag gcgtccgatt ggctccttta tgtttcttgg tccaactggt gtcggaaaaa
     2941 cagagctagc aaaggccttg gccgaattac tctttgatga tgagtcagcc cttattcgtt
     3001 ttgatatgtc tgagtacatg gaaaaatttg cagcctcccg tcttaatggg gctcctcctg
     3061 gctatgttgg ctatgatgag ggaggagagc taaccgaaaa ggttagaaat aagccttatg
     3121 ccgttcttct ttttgatgag gttgaaaagg ctcacccaga catctttaat atcctgctgc
     3181 aggtccttga tgatggtatg ttaacagata gtcgtggatg taaggttgat ttttcaaaca
     3241 cgattattat catgacgagc aacctaggag caactgctct aagagatgat aagacggttg
     3301 gatttggcgc taaagcgatc ggtcatgacc atcaagcaat ggaaaagcgt attttagagg
     3361 aattgaaaaa ggcttatcgg cctgaattta tcaacagaat tgatgaaaag gtggtcttcc
     3421 atagcctaac acaggaaaac atgcgtgatg tggtgaaaat tatggttaag ccgctgattg
     3481 cagccttggc agaaaagcat attagcctta agttccagcc atcagctctc aagtacttgt
     3541 ctgaagctgg ttacgatgtt gaaatgggcg ctcgcccact tcgtcgcacc ttgcaaacag
     3601 aggttgagga caggttagca gaattaatgc tgtcaggaga gttatcaagc ggtcaaagcc
     3661 tcaagattgg tgtatcacgt ggaaaactag cttttgatat cgcttaatgc atgactttgc
     3721 ttgatattaa gctaagagct ttgagagagt ctgagacaaa aagtttctca ggctcttttt
     3781 gtcgtatggt gatgaagtac tagagtgaga gtttaaagcg tagcagacag ataggattta
     3841 attttaatcg aatttagcga aaaataggta ttttgaagat ttagctacca atttagctgc
     3901 caaaatagta tctcatttga ctatttttct tagctgagat ataatgaaaa tagaaaaagg
     3961 acagttgctc aaaacaacta cccaatgcag aaccgtttaa gacggtagct tgtttttagt
     4021 taaaaaataa ccgttactcg ctaaagttag acggttattt tttattgctc atttttacga
     4081 taataacaac taagccaatg agtgaaagta gaaaactacc gaacccaagc atgagttgca
     4141 ttgcctcgta aacggacaat attcgctcct ttctctttgg attttagcac ttacagtcat
     4201 aagcaccacc acctttcaga aattagagcc accgccttaa cttttctgca gaaaccatta
     4261 taccatagtc atacgaaata gctgtctgat gttgaaaatt cagatggctt ttttgtgtcc
     4321 tttgcttgca gggaagaaat ataccctaaa atcgttttta agcgattgtt tgttgagatg
     4381 gtatattttt tatcgaatac gacataaaaa ttgaatatgg ttattctatg acttctgatt
     4441 tattgtatac tattattaga aattgaaagg agaactttca tgaaaaagtc gaccaaagct
     4501 tttattgctt taatgattct cataggaggg ttgcttatgg tatttagttt gaatggtaaa
     4561 atcacagaag aacaacaaaa aaaggatttg gaaaccagca ttgctaagct gcttgttcat
     4621 gactatgaag gggttaaaac cattaaattt caaggatggg gacattctcg tgaaacgggt
     4681 tcgtggggaa cgacggtgat tattaatgag agtaatcaaa tgagtttttc tttttctagt
     4741 ataaaaactt tagaagatat aggaagcaca agatataatc ccaatacttt taaattggta
     4801 gaaaaacctg aaactgattc taaaccaaga attatggata ggatgaacga gattaatgcg
     4861 acctctcttg caggtgttac tgttatctat tcaaataaca atcaggagga ttaatatggc
     4921 gatatccgat agtagctata atgagttagc aagacagacc tataatatcg aactaaggaa
     4981 agctaaattt aatgatgtcc ctattgtttt aatggaaaga ttattagcag gagaatttaa
     5041 cttataacag ataacattat agaaaaactg tttagcttta ttttttactc at
//
LOCUS       DARYXZ010000083         4747 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYXZ010000083 DARYXZ010000000
VERSION     DARYXZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4747
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(36..632)
                     /locus_tag="TV186_001911"
     CDS             complement(36..632)
                     /locus_tag="TV186_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1533263.1"
                     /translation="MKRKIALLVPVIVLCICGLFFYMNRNSDDIDVAFTVKNETKEKI
                     DTVGIAMGNKCILNRTNGEKFYFPKDLIKEKQGKAIVFVVSKDGIIAKSGEIDLKENK
                     EVSIREIKEGEISLDIAAQKTDIKISIPRLDDWKVSTDEKFIKGSYEANTDSQYTLYL
                     LGKGGNLGISGTEMKGVRVIVSWEKPKDKIDSWLVFND"
     gene            complement(629..1303)
                     /locus_tag="TV186_001912"
     CDS             complement(629..1303)
                     /locus_tag="TV186_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1533264.1"
                     /translation="MQNEKELQITLRNVSKKYGEHSILENISLDIYKGDFVCIFGKSG
                     GGKTTLLNIIGTLENYDSGSVTCFSNRDPIKAPKVGELLRREKIAYLFQNFALVEKMT
                     VEENMMLAAKYNQEKNKKNLIEAALNKMGISDKLKSKVYELSGGEQQRVALARNMIKP
                     FEIMLADEPTGSLDYENKKIVIDTLIRLNDEGKTIVVVSHDKDFEKVAHKNYIIEKSA
                     IREVLR"
     gene            complement(1304..3472)
                     /locus_tag="TV186_001913"
     CDS             complement(1304..3472)
                     /locus_tag="TV186_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533265.1"
                     /translation="MKKTVGILAILLIIVIGIGKFFYSDGMFLNIFIKEFNTTVNIVT
                     KPEIADKTIIELQKIANKNDLSFIKEEYIPKNSRFDKQKMKIYIHLNDSEWFKKSFRN
                     ISIADSKDKLNDFENVKSMSLLTSKDISLIPFENVNKEKVNGDYHVRGTEENINKFIE
                     EINQNEKLKTEVVVNPDFIVSSEFTQKQAYLYMLTIFIIFVATVFCLIIYNGMLSKEL
                     SISILLGCDELTLAIAKVLNILAIPAIVGLVLTIGIIEYLVAPSDILGFMISMKTILI
                     LVAFIIGGLISIEFILIYLKLKGINVIALLKGYRRSYHRSSFFIKTGSIVMVLYLAIV
                     SILGLTDYLSMRQYIPTWESSKYYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLD
                     DSGAILFNAPNVRKEGMNDDEEYLNQQPFQGNYAYVNKNYLHIANLLDKDTNKIEQYK
                     IHENEWIVFVPEDVKITELDKEKIHEDHIFQNIKKQGTIIETYVRLKDNQSVFSFDSG
                     KRIDEANLKNYVLVAVNGKELLPDHGIKLSSLVNGQLHPYVKEPSRAYESLKDIIEET
                     ESEPFILYISSVYDDIVSRIDEYKMEASIYVIGLVLSIVILATLLKIDKETYFYNHGQ
                     RIDVSRLLGYGFFDIHHKKIIGNIVGYIISIIILFMVIMVTGVISDVGLFIPRDGWSM
                     SKLLISLIIGICGSFICFGIEILQLKKSERSIVLRLKEGC"
     gene            complement(3580..3963)
                     /locus_tag="TV186_001914"
     CDS             complement(3580..3963)
                     /locus_tag="TV186_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL1533266.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
     gene            complement(4241..>4747)
                     /locus_tag="TV186_001915"
     CDS             complement(4241..>4747)
                     /locus_tag="TV186_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1533267.1"
                     /translation="DFFSYLKFNLNEIPLNLMDVDIKIFFSQWEEEKSLSIKDHLLIL
                     EFLDLENSKIKTEPQLLLRIMENLITNAVNYSVKGTSININVEEINGMLKISVINDVS
                     PNLNVNWNMVTSKFYRGDLSRRISNNGSGLGLTIVNDIVKHLGGNFEIGEENKRVCAK
                     VILPYRLN"
BASE COUNT         1514 a          925 c          472 g         1836 t
ORIGIN      
        1 attattttac aacttttatt acaaatattg tatttttaat cattaaatac aagccaacta
       61 tctattttat cttttggttt ttcccaactt acaataacac gtactccttt catctccgta
      121 ccggaaatgc ctaaatttcc gccttttcct aataaatata atgtatattg cgaatcagta
      181 tttgcttcat aagagccctt gataaatttt tcatctgtac taactttcca atcatctaac
      241 ctaggaatac taatttttat atctgttttt tgagcagcta tatccaagga tatttctcct
      301 tcttttattt cccttatact tacttcttta ttttctttta aatctatttc ccctgacttt
      361 gctatgattc catctttaga tactacaaaa acaatagctt tgccttgttt ttctttgatt
      421 aggtcttttg gaaaataaaa tttttctcca tttgttctat tcaaaataca tttatttccc
      481 atcgcaatac ccactgtatc tattttttct tttgtttcat tttttactgt aaatgcaaca
      541 tcaatatcat cactatttct gttcatgtaa aagaataaac cacaaataca cagtactata
      601 accggtacta ataaagcaat cttccttttc atctcaacac ctcccttata gctgactttt
      661 caataatata attcttatgt gctacttttt caaaatcctt atcatgactt acaactacga
      721 ttgtcttacc ttcatcattt aatctaataa gtgtatcgat tacaattttt ttattctcat
      781 aatcaagaga acctgtcggt tcatccgcca acataatttc aaacggtttt atcatatttc
      841 ttgcaagagc taccctttgc tgttctccac ctgaaagttc ataaaccttc gattttaatt
      901 tgtctgaaat gcccatttta ttcaaggcag cttctataag atttttctta tttttttctt
      961 gattgtattt tgcagcaagc atcatatttt cctcaaccgt cattttttcc accaaagcaa
     1021 aattttgaaa taaataagca attttttctc tgcgtaatag ctctcctact ttaggagctt
     1081 ttataggatc tcgatttgaa aaacaggtta cactaccact atcataattt tctaatgtcc
     1141 caattatatt taaaagtgtt gtttttcctc ctccactttt cccaaagata caaacaaaat
     1201 ctcctttata aatatccaaa ctaatatttt ccaaaatact gtgttctcca tatttcttag
     1261 agacatttct taaggttatt tgcaattcct tttcattttg catttaacaa ccctccttta
     1321 acctaagtac aatgcttctt tcacttttct ttagttgtaa aatttctatg ccaaaacata
     1381 taaagcttcc acaaatacct attattaaac taatcaaaag tttagacata ctccaaccat
     1441 ctcttggtat aaacagtcca acatcgctta ttactcctgt taccataata accataaata
     1501 aaataataat acttatgata taaccaacga tatttccaat aattttctta tgatgtatat
     1561 caaaaaatcc atatcccaac aacctagaaa catctattcg ttgtccatga ttataaaaat
     1621 atgtttcttt atctattttt aataacgttg ctaaaataac aatagataag acgagaccaa
     1681 taacatatat acttgcctcc atcttatatt cgtctattct tgaaactata tcatcgtaaa
     1741 ctgagctgat atagagtata aacggctcag attctgtttc ttcaattatg tccttcaaac
     1801 tctcgtatgc cctactaggc tctttaacat atggatgtag ctgcccattt actaaagatg
     1861 atagtttgat tccgtgatct gggagtaatt ctttcccatt tactgctacc aaaacataat
     1921 ttttcaagtt tgcttcatca attcttttgc cactatcaaa agaaaataca ctttgattat
     1981 ctttcagcct tacatatgtt tctataattg taccttgttt ttttatattt tgaaaaatat
     2041 gatcttcgtg aattttttct ttgtcaagtt cagtaatttt aacatcttct ggaacaaaaa
     2101 caatccactc attttcatgt attttatatt gttctatttt attcgtatct ttatctaaga
     2161 gattagcaat atgtaaataa tttttattta cataggcata attaccttga aaaggttgtt
     2221 gatttagata ctcctcatca tcattcattc cctcttttct aacgtttggg gcattaaata
     2281 atattgctcc actatcgtcc aaactattcc ataagttatt cagctttgga ataacaattt
     2341 catggaactt atcatcatct ttttcataac tccaagacca tgcacaagcc atatttgcat
     2401 aatactttga gctttcccaa gttggaatgt attgtctcat actcaagtaa tcagtgagtc
     2461 ctaaaatact tacaattgct agataaagaa ccataacaat cgaccctgtt tttataaaaa
     2521 aagaacttct atgataactt cttctataac ctttcaataa ggcaataaca ttaattcctt
     2581 ttaatttgag ataaatcaat ataaactcta ttgatattag acctcctatt ataaaagcaa
     2641 ctaaaataag tattgttttc attgatatca taaatcctaa aatatcacta ggagcaacta
     2701 aatattctat aattccaatc gtcagtacaa gtcccactat tgctggtatt gcaagaatat
     2761 ttaaaacctt agcaatagct aaagttaatt cgtcgcatcc tagtaaaatt gatatcgata
     2821 attcctttga aagcatccca ttataaataa ttagacaaaa gacagtagct acaaatataa
     2881 taaaaatcgt aagcatatat agatatgctt gtttctgtgt gaattcacta gaaacaataa
     2941 aatccggatt aaccacgact tctgttttta atttttcatt ttgatttatt tcttcaataa
     3001 acttattaat attttcttcc gtccctctta catgataatc cccattaact ttttccttgt
     3061 tgacgttttc aaaaggaatt aagcttatat cttttgatgt cagcaaactc attgatttta
     3121 cattctcaaa atcattcaat ttgtctttgc tatcagcaat agatatattt ctaaaagatt
     3181 tcttgaacca ttcagaatca tttagatgaa tgtaaatctt cattttttgt ttatcaaatc
     3241 tactattctt aggaatatat tcttccttta tgaagcttaa atcattttta ttagctattt
     3301 tctgcaattc aattattgtt ttatcagcta tttctggctt tgttacaatg tttacagtag
     3361 tattaaactc ttttatgaat atatttaaaa acatgccgtc tgaatagaaa aactttccta
     3421 taccaatcac tataattagt aaaattgcca atatacccac tgtttttttc attctgtatc
     3481 atctccaact ttataaaaat agcgagtatg agtaatgcca caatgctaaa ataacaacgt
     3541 ggcaccgctc aaactcgttc aactattttt tatttattgt tatttaacat cagcccaagc
     3601 cctattacca cttaaagctt tttcccaaga agcttctgct ctacttccag cgcttgtcca
     3661 acccgaataa gagaattgac caccagcacc ttgtactgta gttttatgtg ttttattatt
     3721 gtgatcgtat ttagaccaaa catatcgact acctacacca tgtctccatt ttccacctaa
     3781 aaaacttttc catccgctat cataactgaa caactttggc tgagtataat cttcttcaaa
     3841 tacttccacc tcataaccaa gaccttcaac atatggcaag tttgtttctt ctgctgcaaa
     3901 tgctggtaca gatgatgcta acatcaaacc tgttaataat actaatgaca atgctttttt
     3961 catgataaat tctcctctct caaatactta aattttttgt aaaatttttc ttccgaataa
     4021 agtttcccaa aactctactc aatctccgtt cctataccta tgaggattat tgtaattcat
     4081 aaaactccac ctccatttta tatatttata atcacagatg cttattcaaa ttaataattc
     4141 ctttcaaata taaaagagct atccttactc acattataga atagctcttt gctttatact
     4201 taacggtatc tttgaataat tcttgcgttt tctttgcgat ttaatttaat ctatatggaa
     4261 gtattacttt agcacaaact cttttattct cctctccaat ttcaaaattt ccacccaagt
     4321 gttttacaat gtcatttaca attgtaagtc caagtcccga tccattattg cttattcgtc
     4381 ttgataaatc tcccctataa aactttgaag taaccatatt ccaattcaca tttaaatttg
     4441 gagaaacatc gtttataaca cttattttta acattccatt tatttcctca acatttatat
     4501 tgatgcttgt tcctttcaca gaataattaa ctgcatttgt aattagattc tccattattc
     4561 taagtaaaag ttgtggttcc gttttaatct tactgttttc caaatctaaa aactccaaaa
     4621 ttaaaagatg atcttttata gataagcttt tttcttcttc ccactggcta aaaaaaattt
     4681 ttatatctac atccattaaa tttagtggaa tttcatttaa attgaatttt aaatatgaaa
     4741 aaaaatc
//
LOCUS       DARYXZ010000084         4590 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYXZ010000084 DARYXZ010000000
VERSION     DARYXZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4590
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..405
                     /locus_tag="TV186_001916"
     CDS             <1..405
                     /locus_tag="TV186_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1533268.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            414..1085
                     /locus_tag="TV186_001917"
     CDS             414..1085
                     /locus_tag="TV186_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533269.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1102..3375
                     /locus_tag="TV186_001918"
     CDS             1102..3375
                     /locus_tag="TV186_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533270.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3850..>4590
                     /locus_tag="TV186_001919"
     CDS             3850..>4590
                     /locus_tag="TV186_001919"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1533271.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAE"
BASE COUNT         1497 a          891 c          946 g         1256 t
ORIGIN      
        1 ggaagaggct tttataaaaa atacatgaat gcctatgggc aggtggcaag gctgcattct
       61 cagcaatggt acaccgatgt cgttcatctt cctgttgaat ttcctatgtc agccgatggg
      121 cataggccag tctctgagag gtaccggaca ctatcagaca aagaaatcag agaaggcttt
      181 ctctccattg gaaaaacacc ggagcttgtc agtggcagtc aggtcgagag attgcgaaaa
      241 atcattaacc tatatgacct gccggttgtc gttccaattg acgaggcagt cactcaagca
      301 gaggagcaaa tcagaaccaa cagagaagct gtctccaagc ggattattga gcagtataaa
      361 gagccttcat taaaagaaaa aataaaattt atatcagaat tttaggagtg tagatgattt
      421 catttaagaa tattagcaag acataccaag tcggagacca agaggttaaa gtattagacg
      481 atgtttcctt tacgattgaa aagggaaggt ttactgttat tttaggcccc tctggttcag
      541 gaaagagcac gctcttaaat ttacttggag gaatggaccg ggcaagcaag ggaaccttta
      601 tctttgaggg taaggacatt acagccttaa atgataaagc attatctgat tatcgcaaag
      661 aggttgtagg ctttgtcttt cagttttaca atcttattcc aagcctaaca gccttagaaa
      721 atatcagtat cgccgcacag ctaaccggaa acacagcaca atcagaggta ttgttggata
      781 aggtggggtt atctcatcgg aaaaacaatt tccctagcca gctgtcaggc ggagaaatgc
      841 agcgcgtatc catagccaga gctctggcaa agaagccaaa attattgcta tgtgatgagc
      901 ctaccggtgc ccttgattcc aaaacagggc agcacattat gcagctactt caggaagcgt
      961 caaaggacga ggacgtagcg gttgtcttgg tgacacataa cactgaattt aaagcttttg
     1021 gcgataccat tatttaccta aaggacggaa agataagctc gattgatcat aaacaatcag
     1081 tttagaggat tggagctaaa catgaaatat cttaatttaa agctaaggcg agatttaaag
     1141 catcattggc agcaattctt ttcagtgttc ttgatgtcct tattaagtgt tttaatcttt
     1201 gttggtctac agggtgcttg gcatgggctg gaaaaaagct tagacaacta tatatctacc
     1261 tctcatttgc caaccgtttg ggtacaggct actaatctaa caaaacagga cattgaaaaa
     1321 atagaggcct taaatcaagt cagcaaggtt agacctaaga ttagggtcac tgctgctatt
     1381 gattctgaca gcgacctaga gcattactta acgctagatt cattacagtc tacctcagat
     1441 caggtgacac gtgttgtagc tggcgaggcc ttttcaacca aagaaaccga taaagtatgg
     1501 ttgaacaagg aatatgctga cgctaaccac ctatccctcg gtgataagat cagcttaaca
     1561 ctatcaggtc aatcaattag tgtgactctt gcgggtcttg tccagtcagc agacaggatc
     1621 tactttacag gcagcttaga gtatatagct cctaattatg ataactatgc ctacggctac
     1681 atctcaaaaa agagcttagc taagctcctt cagacgcagc tgcctgataa tatggttgac
     1741 atttacgcct cgtctgacga tcttcgagac gacatagaga acattttagg caataagctt
     1801 gtttcttatt acaatcaaac aaccctaact gacgtctctg aggcagttga tagagtagga
     1861 cagattagga atctctctta tttgttctcc tttatcttca tcttactagc tattctatcc
     1921 atgtttacca cgatcagacg tctcatcgaa agtcaaacaa aggaaattgc tatcatcaag
     1981 gccttaggct attctaacat acaggtcagt ggccactaca tttcctttgg cttgttggtt
     2041 ggaacattag gtgctctttc tggtcttctg gtatctcctg ctatgtcctg gtttgtccta
     2101 gagacccaaa agagaatgtt ctcacttcct aagtgggaaa ttgcttactc tctgtcttcc
     2161 ctagtagttg cattactggt ggttatgatt tgtgtgacat ctgcttactt tgcttctcga
     2221 aaagccatta aagggctgcc agcagtattc ttacgaggaa aaaacaggga cgtcaagcat
     2281 attttgctcg aaaaaatcaa gcccttatgg cgtagtattt ctgacgaagc taagtgggct
     2341 atacgtgatg ctttgacaca ccgcatcaga attttaatgg ggattatagg ggtagctggt
     2401 agtatgatgc ttttaattgc cggtattggc atgcctatct ctatgaatca ccttgttgat
     2461 aaggcctata acaaggactt tagctactcc aaacgcttga cggtttctga ctacgaatcg
     2521 gccaataagg cctataaagg ccaatgggtg caaatcaatc aagcccactt ctcaaaagat
     2581 gacggctaca atcgtctctt gattattatc agcaagggaa gccttgttaa cgccaccaca
     2641 gaagatggtg acaagataaa agagggtggt ctctatgtta ccaacagctt tgccaagcta
     2701 gccaatatca aggttggaga caagctatct gtcacaccct accaggataa gcatcagtat
     2761 acctttagtg ttaagggaat tctgaccagc gaaactaatc aaggtgccta tatcatggct
     2821 gataccttca aaaaagcagg cggagctttt cacccacaca cattgttagt agataagcaa
     2881 gtttctgctt ctacaatcgc tcaggatcag aatgttttaa ccgtcattga taagtccagc
     2941 caagaaagca atgcctatga ccttgtcaat agtctaatga gtgtcttttt gatgatcatt
     3001 ggctttgcct tgctgctagt catcgttgtg ctgtataatt taggctcttt aaattttgta
     3061 gagcgcacaa gagactacgc aacccttcag gttctaggat tttcaaaaag aaatctccaa
     3121 aacataacaa tgctcgaaaa tctcatgaca acctctgtgg gctggctctt gggaattcct
     3181 atggggattt ggtttttaga gcagtatgtc gccaccttct ctacgatacg tcttgaatat
     3241 acggcttatg tcacttggca ggttctgcta gcggcaagtg tccttgtctg gctaacatca
     3301 ttaatgacca ctcttttcat cagtagaaag attagaacaa ttgacatggt tgatgcctta
     3361 aagggagtcg actaacctca ctttatcaca tacctgactc tctctctttt atggttaagc
     3421 atcatcactg cactggttct gatatgatga ctgataaagc tgtaattgtg ctgtaacaag
     3481 cactgtcatt acatagcaac acccttaaaa acaagcatca gatttggtgc ttgtttttga
     3541 atttattgct aatgctaaac gcaacgatta tcacaaatca tgcagtacac gcttataaca
     3601 gcttaagcat gcccattatt caaaaaacgt tgatcaaaat gacttccctg aagtttagat
     3661 cattcctcaa tttattgata caaatgtgat aaagtcatac gatcttcttg tttattaaaa
     3721 aaaaaaaaaa acgaaactac ggagagaaag atgagctttg tcgtttctca cttccaaccg
     3781 ccatgttaaa atcttctctg agaaagaatg ttataaaaaa taatcattct atcaccaaag
     3841 gagagaaaaa tgataactaa aaaacagaga aaactaaaaa gacacacaac aatcagacgc
     3901 ctgtgtcatc aagccctagc agctaccctc atcacaggaa gcctgatggg aacaggacta
     3961 cttggaaata aagtcgtgta tggggatatg aaaagcgatg ccaaaaaggt attagcaaca
     4021 ttgcaaaaag gtaatcataa acaagagtta aaaaaagttc ttagaactat tggtgatgat
     4081 agtttgctat tattatggtt acttgtatcg ggtgattcca atttagatga aagtaataaa
     4141 agttttgatt atttatcaat ttggaatact ggatctagag ttggtaaagt gatatctcct
     4201 actgaatact ttaaacaaga atcaaaaaac actgaaaata ggcaagctgt ttatagtgaa
     4261 tttaaacaac gcgtagaaga acgatctaaa aaagccaagg aagccactga agcactaaac
     4321 caaaaagctc aattggaggc tacagttaaa aatataaacg aagaacttga aaaaactaga
     4381 gaaggtttta aagttgtgag tgaaaactca aacaaattag aaaaacaatt aatggctgag
     4441 aaaataaaaa cacgtacagc tgaagaaact gccaaacaag ctaaaaccga taaagaaaaa
     4501 gcagaggctg aagctaaaaa agcgaaagag gaagctaaga ctgcggaagg aaaagttaaa
     4561 caagcagaaa ctgagaaaag gaatgcggaa
//
LOCUS       DARYXZ010000085         4506 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYXZ010000085 DARYXZ010000000
VERSION     DARYXZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4506
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(240..1910)
                     /locus_tag="TV186_001920"
     CDS             complement(240..1910)
                     /locus_tag="TV186_001920"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL1533272.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            2108..2800
                     /locus_tag="TV186_001921"
     CDS             2108..2800
                     /locus_tag="TV186_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL1533273.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            2793..3338
                     /gene="coaC"
                     /locus_tag="TV186_001922"
     CDS             2793..3338
                     /gene="coaC"
                     /locus_tag="TV186_001922"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL1533274.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            3395..3967
                     /locus_tag="TV186_001923"
     CDS             3395..3967
                     /locus_tag="TV186_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1533275.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
     gene            complement(4191..>4506)
                     /locus_tag="TV186_001924"
     CDS             complement(4191..>4506)
                     /locus_tag="TV186_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1634 family transposase"
                     /protein_id="HEL1533276.1"
                     /translation="TELESRPVYVWTEKHIQAHFLTCFIALVHLRLLQHQIDWQMSPE
                     RIITALNSAKVTPLQDNYYRLQESLDMQELNRLLGIEWAKGIVKFEELKHYAKNPYTT
                     LK"
BASE COUNT         1338 a          992 c          849 g         1327 t
ORIGIN      
        1 ttaattttat catttaatat taaaagtcag attattaaaa aatatcccta ccaaagcaga
       61 attaaagcat taatgattgt caatatgaca cctatactgg taaaaaaaga ttgtgaataa
      121 cgattaaaat agtaaaatat gagctattgt tatcagctta tccttagaca ttaaaaaaga
      181 ttgaagaaac cccctttctg aagctttctt caatcctgat tctggctata acaaataaat
      241 caaaacaatc ctactgctgt accgtcttcg gtgacgtcca tcttcatagc tgcaggaatc
      301 tttggcaagc ctggcattgt catcacatct ccagttaagg cgacgataaa gccggcaccg
      361 gtcttaggca ctaattcacg aatggtaatg tcaaactgat ctggcgcgcc taggagcgat
      421 ggatcgtctg aaaagctata ctgggttttg gccatgcaaa caggcaattg atcccaacca
      481 aactgggcaa attgcttgag ctgattttta gctttaggtc cgaattgcac agccctacca
      541 ccataaattt cagtcacaat tgccttaagt ttctcctcta agctatcctt gtctgcatat
      601 agacgcttat aggctgcgct ttcctctgta atagccttga caacagcgtt ggcaagagca
      661 ataccgccat cagccccctt ggcccacacg cttgccaatt caaccggaac agctatttct
      721 gcacacaatt cttttaagac ttgaatttct gctttagtat ctgtcacaaa ttcgttgata
      781 gctacaacaa tcggaatatt gaattttcga atattctcaa catgacgctt taaattagca
      841 aagccagacc ggaccgcagc tgtattttca aaggttaaat ccgccttagc aacaccgcca
      901 tgcatcttca aggcacgaag tgttgcgaca ataacaactg catcaggagc cttaggtaga
      961 ttcggtgttt tgatgttaag gaatttttct gctccaagat ccgctccaaa gcctgcctct
     1021 gtaacagtat aatctgccaa ccgcaaagct gttgatgtcg ccagaacaga attacagcca
     1081 tgagcaatat tggcaaaggg tccaccatgc acaaaggctg gtgtaccata gattgtttga
     1141 acaaggttag gcttgatggc gtccttcaaa atcaaggcta atgccccttc tacctttaaa
     1201 tcacgcacat atacaggtga tttatcgtaa cgataggcaa tcacaatatt agctaaacga
     1261 gccttcaagt ccttaagatc agtcgccaag caaaggatag ccatcacttc agaggctact
     1321 gtaatatcaa aaccgtcttc tcttgggaca ccattgacag gactccccaa gccaacaatg
     1381 acctgcctaa gagaacggtc attcaaatca aggacacgct tccagatgat acgacgcggg
     1441 tcaataccaa gctcattgcc ctgctgaagg tgattatcaa taagggctga taaagcatta
     1501 tgagctgtgg taatagcatg catgtccccg gtaaaatgaa ggttaatatc ttccatcgga
     1561 agaacctgag cgtagccgcc acctgcagca ccacctttga tccccataac cggtcctaaa
     1621 gagggctcac gcaaggccag catggttttt ttaccgattt tagtcaaggc atctgccaaa
     1681 ccaatagaca tggttgattt gccttcacct gctggcgttg gattaatagc agtcactaaa
     1741 atgagcttac caggcttatt gtcctctact gatttgattt tttcaaagga taatttggct
     1801 ttgtagttac cgtaaagctc caaatcatca gcatcaatcc ccaccttttt aacgatttct
     1861 gtaatcggct ttaaggggac actttgagca atttcgatat ctgatttcat gaaaactcct
     1921 tgactcttac ttgatagtgt tattatatca cacttcatct caaacgtaca ttgatttgtt
     1981 ctatatacaa aaatgttcgt ttttataatg gttctgaaag gaaaaaagct tagtagcgtc
     2041 agcattgtca gtaaaaataa ttttaattag tgattttatt tactattctt gctttttctg
     2101 ataaaatatg gctatgaaat tattaatcac atcaggcgga acgaccgaag caatagacgc
     2161 cgttagaggg attaccaatc attccactgg ccagctagga aagatagtag ctgagacctt
     2221 tctagcaaag ggatttgacg ttactctagt gacaacaaaa acttcagtaa aaccagcaca
     2281 gcagcctcat ttgaccattc gtgaggtgac caatgttgat cagctgatgg ctatcttaaa
     2341 agaggaggtt cctaagcacg accttctcat tcacagcatg gctgtttcag attatagccc
     2401 agtgtacatg acagactttg atacagttgc agctgctgat catttacaga cctttttaac
     2461 agcaagcaat aaggaagcca aaatctcatc ggcagctgat tatcaggtgc tctttcttaa
     2521 aaaaacacct aaagtcatat cctatattaa ggaatggaat cctaatataa ggctagtcgg
     2581 ctttaagcta ttggtcaatg ctccagctga ggagctaatt tcagtggcac gagatagcct
     2641 gcataaaaac aaagcagact atatagtagc caatgaccta gcagatatta aggccaatca
     2701 gcacaaggct tttcttgtca atgacaaaac agtctgctct gccagcacca aagaggagct
     2761 tgcacaatta atctatgaaa ggataatagc caatgactaa gcgaataaca cttgcggtct
     2821 caggtagtat ttctgcctat aaggcagctg atctcaccag ccaattaacc aaaaaaggct
     2881 atgaggttac tgtgttgatg acgcaagcag ctactgcctt tatcactccg ttgaccctac
     2941 aggtcttatc gaaaaatcct gtccatctag atgtcatggc agagcacgat gtcaaaattg
     3001 tcaatcatat tgagctagct aaagcaacag atctatttgt ccttgctcct gcaagtgcca
     3061 ataccattgc tcatttagcc tacggctttg ctgataatat ggttaccagt gtcgccctag
     3121 ccctgcctga ggcaacaccc aaactcatcg ctcctgctat gaatactaac atgtacctta
     3181 acccaattac tcagggaaac atcaaacgct tagctgatct tggctttcga gaaataccac
     3241 ctaagacagc actccttgcc tgcggcgaca gaggacctgg ggccttagca gatattgatg
     3301 atatggttac agcaattagt cagcagctag caagatagct ggtcaccgat tagcaattgc
     3361 tgtattataa tataaaaatt taatggagaa tgcaatgaat cataacaaat cttctgaaat
     3421 ctctcgtatt gccatctttt ttgcagtcat gctggttatt cacttcatta gtagctggtt
     3481 tttttatatc tggcctgtcc caattaaacc aacactcgtc catattccag ttattgttgc
     3541 ttctatcatg tatggtccgc gcactggagc tatcttagga ggcttgatgg ggattgtcag
     3601 tgtgatcaca aataccttgg ttttacttcc aacaagccat cttttctcac catttgtcac
     3661 aaatggtaat ctggcttcct tgatgatcgc tatgctgcct cgtatcctga ttgggatcac
     3721 tccttattac tgttataagc ttatcaaaaa cgagcttggg cttgtcctag ctggtcttgt
     3781 tggctcgctg acaaacacca tttttgttct ctcaggaata tttatctttt tcccaacagc
     3841 ctctggtgac aatgtcaaaa cgtttctaac taccattgta tctggcaatg ctattactga
     3901 aatgattgtt tcagctatcg ttaccattac tcttatccca gctttatcca agctcaaaaa
     3961 atcataatat tgctcaagct atgaagcatg ctgtctgata aggatagcat gctttaatga
     4021 tatgtgacaa gcaaggaaat tgatccttat gtgaaaaaat gattggaagc tattacagaa
     4081 aataagtgat ttttcctttt caacatgata taatcccgac tttatcactt aaaaacaagt
     4141 aaagaccagc taaccccttg tgtcccaagg gattttgctg gtctttaaat ttattttagt
     4201 gttgtatatg gatttttagc gtaatgtttg agctcttcaa acttaacgat tcccttcgcc
     4261 cattcaattc ctagcagtct gtttaactct tgcatatcaa ggctttcttg aagtctgtag
     4321 tagttatctt gtaacggtgt taccttggca ctgtttaagg cagtaatgat acgttcagga
     4381 ctcatctgcc aatctatctg atgttgaagg aggcgtagat gaactaaagc aatgaaacag
     4441 gttagaaagt gagcttgaat gtgtttttcc gtccaaacgt aaacaggacg actttccagt
     4501 tctgtt
//
LOCUS       DARYXZ010000086         4388 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYXZ010000086 DARYXZ010000000
VERSION     DARYXZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4388
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            104..286
                     /locus_tag="TV186_001925"
     CDS             104..286
                     /locus_tag="TV186_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1533277.1"
                     /translation="MLIYDEFKQAVDNGYITGDTVAIVRKNGQIFDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            484..873
                     /locus_tag="TV186_001926"
     CDS             484..873
                     /locus_tag="TV186_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL1533278.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            870..2081
                     /locus_tag="TV186_001927"
     CDS             870..2081
                     /locus_tag="TV186_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1533279.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            2094..3440
                     /gene="asnS"
                     /locus_tag="TV186_001928"
     CDS             2094..3440
                     /gene="asnS"
                     /locus_tag="TV186_001928"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL1533280.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            3740..>4388
                     /locus_tag="TV186_001929"
     CDS             3740..>4388
                     /locus_tag="TV186_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1533281.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEAGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPKGDRGEQGPKGERGEQ"
BASE COUNT         1283 a          914 c         1108 g         1083 t
ORIGIN      
        1 tcacacacat gtattcacac attggcatat ccgttataac ggacttgtta aaattagtcc
       61 attaaactag actttttacg aataataagg taggaggtaa tttatgctaa tatacgacga
      121 gtttaagcag gcagttgata acggatatat cacaggagac acagtagcga ttgtgcgcaa
      181 aaacggacag atttttgatt atgtgttgcc gcatgaggaa gtaaggaacg gggaggttgt
      241 gacagacgaa aaagtggaag aggtgatgag agaattagac aaataaaaaa gacctcgtcc
      301 agaagtcggg gaattgtcgg ggacaacgtt tgtaaatgtt tctattccaa cataaaacat
      361 tttttgatat aataggaagg atcatatgca aaggagctga aattggacaa gcacaaaagg
      421 ctcaaaacag ttttatatca atgtgccagc ttggtcgtac tgctttgtct tggagtgatg
      481 agcatgtttt atcttgctgt tcatgatcaa tttgacaaga aatcaaggtt agccgagata
      541 gcaaaatcaa gagctggtgt catctcaatt gatcatattg attgctatca tggcactcag
      601 agctacctca gtctttttgg aaaaaacaag gcaggcaata ccatcatcgt cacaatagag
      661 gagcaatcag agcagctctt gcttagtcgc cctagcaatg gcattagtgc taaggaagca
      721 caggaaattg cctaccatgc cggagcaagg actattgaag cagtgacatt tgggattgaa
      781 aaccacaaga ggatttggga ggtggctgct caaaacggct actatctgat tgatttcaaa
      841 accgcaaaag tgatcaaaaa ggaggtttta tgaccaagct atcaaggcgc gtgttagcaa
      901 tggaagaaag cgtcacccta gcagcaggtg ctagagcaaa ggcactaaag gctcagggac
      961 gcgatatttt aagcctaact ctgggagagc cagattttat aacaccgcag catatccaag
     1021 aaaaggccat tgaggccatc accactggta aggcaagctt ttacactgtt gcttcggggt
     1081 tgccagagct caaggacgcc attgctgatt acatggcacg atcctatggt tatattccta
     1141 ccagacagga gattgtagtg gggacaggcg ccaaatacgt tttgtatgcc tttttcatgg
     1201 ctgttttaaa tcctggtgat caggtgttga ttccgactcc ttattgggtt tcttatgctg
     1261 atcagattaa aatggtagac ggggtaccgg tctttgtaca gggcttggag gaaaatcaat
     1321 ttaaggtcac agtagagcag ctagaggctg ccagaactga tcaaacaaag gttgttttga
     1381 tcaattctcc gtccaatcca actggcatga tttacagccg acaggagctt gaagccattg
     1441 gcaattgggc tgttcagcat gatattctga tcctggcaga tgatatctat ggtgcattgg
     1501 tctacaatgg caatcaattt actccaatat cagccttatc agaggctatt cgtagacaga
     1561 ccattactgt aaatggcgtt gccaagagct atgcgatgac aggctggcgt ttgggctttg
     1621 cggtcggaga cactgatatt atcgctgcta tgggtaagat tatcgggcaa accacctcta
     1681 atgtgacaac agcgtcccaa tatgcagcga ttgaggcctt tggcggtgac caaacgtcag
     1741 ttgaggagat gagacaggcc tttgaagagc gcctcaatac catttatccc ctgctcaatc
     1801 aagttcctgg ctttgaggct attaagcccc aaggagcctt ttatttcttt cccaatgtca
     1861 aaaaagctat ggagatgaag ggctttaccg atgtgacagc ctttactgat gcgatcctag
     1921 aagaggtagg actggctgtt gtcagcggag ctggctttgg tgctccagaa aatatcaggc
     1981 taagctatgc cactgatttg gcaaccctaa aagaagctat cagacgactc aatcagttca
     2041 tgacaactga cagcagccat gacaacaaag agaatgaata gaaaagagac attatgacca
     2101 aaaaatacgt ttccattatc gatgttaaag accatgtagg acaagaagtg acagttggtg
     2161 cttgggtcgc caacaagtca ggcaaaggga aaatagcctt tttgcaattg cgtgatggct
     2221 cagccttttt ccaggcagtt gcctttaagc caaacctgat ccaagccttt ggtgaggaag
     2281 caggagcagc taagtttgac acgattaggc atctcagcca agaaacctct gtcttagtaa
     2341 agggcattgt caaagaggac gctagatcaa aatttggcta tgagctagac attacggacc
     2401 tagaggttat tggggattcc aaggattatc caattactcc aaaggagcat gggacagact
     2461 ttctcatgga tcaccgtcac ctttggctgc gctctcgcag gcaggcagca atcatgcaaa
     2521 tccgtaatgc catcatctat gcttcctatg agttttttga tcaaaatggc tttatcaagt
     2581 ttgatagccc gattttatca ggcaatgctg ctgagaacac aacagagcta tttgagacag
     2641 attattttgg caatccagcc tttctcagcc aatcaggtca gctatacctt gaagctggta
     2701 tgatggcgct tggtcgcgtc tttgactttg gtccggtatt tcgtgccgaa aaatcaaaaa
     2761 cgcgccgcca tctgacagag ttttggatga tggacgcaga ataccccttc ttatcccatg
     2821 aggaatcctt agacctacag gaagcctatg ttaaggcgat gattcagggt gtgcttgatc
     2881 gtgctccaca ggcattggag cttctagagc gtgacacaga gctgctgaaa agatacattg
     2941 cagagccctt caagcgtgtc tcctacgacg atgcgatcag cctgcttcag gagcacagca
     3001 cagatgacga tgccgactat gagccaattc agcatggcga tgactttggc tcaccgcatg
     3061 aaacctggat ttccaattat tttggggtcc caacctttgt catcaactac ccagctagct
     3121 ttaaggcctt ttacatgaag ccggttcccg gcaatgaaga gcgcgtgcta tgtgcggacc
     3181 tgctagcacc agagggctac ggtgagatta tcggaggctc ggttcgtgag gataactatg
     3241 acaaattgtt ggcgaaaatc aaggctgaag gcctaaatcc tgaggattat gacttttacc
     3301 ttgaccttcg caaatatggc tcagtgccgc atgctggttt tggacttgga ctagagcgca
     3361 tggtgacctt tgttgcaggt accaagcaca ttcgtgaggc tattccattt ccacgcatgc
     3421 ttcatcgctt aaaaccataa tgaaccctat cagcgtccgc cattgggcgc ttttttgctg
     3481 cgctgagcag tacttagagc tcaagcctcc cagttagact tggcagagct gtggctcttt
     3541 gcttgagcta ttgtaggcaa aggtatcact ggatctgaaa acaacaaaat cagacaagtg
     3601 atatcaaaat taaaaaaaaa aaaaacgaaa cctaggagga tcggtgagct tattagtttg
     3661 gcactaatca tcattatgct ataattgtct tcacaaataa tttagaaata gctcatattt
     3721 ctatcattaa aggagagaga tgatgaatcg taaaaagcat accaaactca ttcgtcacta
     3781 cagtatctgc tcagcagtgg ctgtcctagc agcagttagc ttgggaacag gtcaggacgt
     3841 acaggcttcg gaacccaatc catatccaga tgtgaggcgt ttccttgatg agaagtacga
     3901 tggagatgtg gataaattat ctaaacaact tcaaggttat tttggtagtt taagagagta
     3961 tatagagttt gaacttaaaa atggcaaaca aggtcctgct ggccctcaag gcccaaaggg
     4021 tgataaagga gaccccggag agccaggtcc tcaaggtcca gtgggccccg ctggtccaaa
     4081 gggtgatcgt ggtttagacg gacgacgtgg cccagcaggt cagcaagggg aagccggccc
     4141 agttggtcct cagggtcctc aaggcgagca agggccaaaa ggcgaccgtg gcgaacaagg
     4201 accaaagggt gaacgcggtg agcaaggacc aaagggtgaa cgcggtgagc aagggccaaa
     4261 aggcgaccgt ggcgaacaag gaccaaaggg tgaacgcggt gagcaaggac caaagggtga
     4321 acgcggtgag caagggccaa aaggcgatcg tggcgagcaa ggaccaaagg gtgaacgcgg
     4381 tgagcaag
//
LOCUS       DARYXZ010000087         4356 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYXZ010000087 DARYXZ010000000
VERSION     DARYXZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4356
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..224)
                     /locus_tag="TV186_001930"
     CDS             complement(<1..224)
                     /locus_tag="TV186_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="HEL1533282.1"
                     /translation="MYNIGVLGCNGNIGSLFMEKVSKWEDNYIYAVSRSHMNFIKKDN
                     IEYIFFDAENIEKLDKFCSKCDVIVNCTGI"
     gene            complement(244..1989)
                     /locus_tag="TV186_001931"
     CDS             complement(244..1989)
                     /locus_tag="TV186_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533283.1"
                     /translation="MFKTTVRILNWSRKYSTRIKKGFILSFLNSVFIAMPIMLSIYVF
                     NLVLGNYYGSTTYGNKEIAIVTTIMIGLVLGRYITAYFKSVNQDSIGYEMSADERVQI
                     GDILKRVPLGFFQENNPGELTTAVTTDLSFFENYSMKMIDIVINGYIMALVMIISISF
                     LSWELGVVAVSGVVLSYFCLLLLRKHSEKNSVFYLNAQSKLVESTMELIIGLPIVKAF
                     NKGDISLKNFNAAILSSKKVNLRIEKEYTPFNCLHLFSLKLASMCIVIIAGMMAINNK
                     IDISIMIAIFIFSFIMFSSVENINSATHVLEILDKTLDNLDKIKNADFLDDNGKDMEL
                     SSHNIVFDKVRFAYDKIPIIKDVSFEIKENTVTAIIGPSGSGKTTICNLISRFYDVSG
                     GSIKIGNVNIKNLTLSSLLSNISTVFQKVYLFNDTIENNIKFGNPNVSKEEIINAAKK
                     SHCHEFIMNLPNGYETIVGEGGDFLSGGEKQRISIARAMLKDAPIIILDEATSSIDPE
                     NEYLIQRAISNLSKGKTVIIIAHRIVTIEEADQIIVLKEGEIAQIGKHTELMSQDGLY
                     RDYMRIRGKTEDWKI"
     gene            complement(1994..3751)
                     /locus_tag="TV186_001932"
     CDS             complement(1994..3751)
                     /locus_tag="TV186_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533284.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEK
                     LLSISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISW
                     EMALAMFITVPFALMAYKKLMGNFNQLYEAQMKSNKYMNSTIVEYISGIEVIKTFNQD
                     SNSYKKYKDAVNLYKDHTLNWFKSTWSIMNFASSILPSTFLGTLPVGMILYLNGTLTP
                     AEFCICLMLSLGIVIPLTQFTNYVNLLKSIEYAVKDINEILCIPNLISIDNNEHICTT
                     NIKFNNVFFSYDNENSVLENINIEIPQNSFTAIVGPSGSGKSTIIKLISRYWDVCGGE
                     ITIGGKNVKDISLNQLNDLIGYVSQNNFLFNESIMENIRMGNPDASDEEVIEVSKICA
                     CHDFIMELEEGYNSNVGSLGSKLSGGQRQRISIARMMLKNAPIILLDEATAFIDPDNE
                     EKIQGAINVLTKNKTLIVVAHRLSTIKNADKIVVLKNKTIFDTGTHDELLEKCDLYKN
                     MWLSHIGAKSKSIVSNIGG"
     gene            complement(3774..>4356)
                     /locus_tag="TV186_001933"
     CDS             complement(3774..>4356)
                     /locus_tag="TV186_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1533285.1"
                     /translation="KNLSCCYGEKIVFKNLNLSIRSGEILGIIGNNGVGKTTLLRCIA
                     GLHKETKGEITLNGDVISGKKRQRLSAMVMQDVNYQLFADSLVEECCLGNNCDNIQID
                     KVLGELKLIESKKSHPMILSGGQKQRLVVANAILSDKKILIFDEPTSGLDYEGMLAVS
                     NELKKLSEKNYYIFVVSHDIEFINEICDRVYEF"
BASE COUNT         1462 a          807 c          453 g         1634 t
ORIGIN      
        1 tctattccag tacaatttac aatcacatcg catttagaac agaatttgtc taatttttct
       61 atgttctctg catcaaaaaa tatgtattct atgttatctt tcttaataaa attcatatga
      121 cttctcgata cagcataaat ataattatct tcccatttag acactttttc cataaaaagc
      181 gaacctatat taccattgca acctaaaact cctatattat acataaacct cctcctatct
      241 atattatatt ttccagtcct ctgttttacc cctgattctc atataatctc tatacagacc
      301 atcttggctc atcagttctg tatgctttcc tatttgagca atctctcctt ctttcaaaac
      361 aattatctga tctgcttctt caattgttac aattctatga gcaataataa ttacagtctt
      421 acctttactc aaattcgata ttgctctttg aattaaatat tcgttttcag gatctatgct
      481 tgatgttgct tcatccaaaa taataattgg agcatctttt agcattgccc ttgctataga
      541 tattctttgt ttttctccac cagataaaaa atcaccacct tcaccaacaa tagtttcata
      601 tccatttggc aaattcatta taaattcatg acaatgtgac ttcttcgctg catttattat
      661 ttcttcctta cttacattcg gattaccaaa ttttatattg ttttcgattg tatcattaaa
      721 caaatacacc ttttgaaata ctgtacttat atttgaaagt aaacttgata aagtcaaatt
      781 ttttatattt acatttccaa tttttatact cccaccactt acatcataaa aacgagaaat
      841 gagattacaa attgttgttt tacctgaccc tgatggtcct ataatagctg ttaccgtatt
      901 ttcctttatc tcaaatgaaa catcctttat aattgggatt ttatcatatg caaatcttac
      961 tttgtcaaaa acaatattat gactactcaa ttccatgtct tttccattgt catccaaaaa
     1021 atcagcattt tttatcttat ctaaattatc taatgtttta tctaaaattt ccaaaacatg
     1081 agttgcagaa tttatatttt ccactgatga aaacataatg aaagaaaata taaatattgc
     1141 aatcataata gagatatcta ttttattatt tatagccatc attccagcta ttattacaat
     1201 acacattgat gctaatttta atgaaaataa atgtaagcaa ttaaaaggtg tatactcttt
     1261 ttctattctc aaattcactt ttttactact taaaatagca gcattaaaat ttttaagact
     1321 tatatcaccc ttgttaaaag ctttaacaat aggaagtcct attataagtt ccattgtaga
     1381 ttcaactaat ttactttgtg cattaagata aaaaacagaa tttttctcag aatgtttacg
     1441 aagtaacaat aaacaaaaat acgaaagtac tactccagaa actgctacaa cacccaattc
     1501 ccaagataaa aaagaaatac tgattatcat aacaagtgcc attatataac cgttaataac
     1561 tatgtctatc attttcatcg aataattttc aaaaaaagac aaatctgtgg ttacggcagt
     1621 agtcaattct cccggattat tttcttgaaa aaatcccaat ggtactcttt ttaatatatc
     1681 accaatttgt actcgttcat cagctgacat ctcataacca atactatcct gatttacaga
     1741 cttaaaataa gcagttatat atctccctaa aaccaatcca atcattatag tagtcactat
     1801 ggctatttct ttatttccat atgttgtact cccataatag tttccaagaa cgagattaaa
     1861 aacatatatt gatagcatta ttggcattgc aataaaaaca gaatttaaga aagataatat
     1921 aaaccctttt tttattctcg tactatattt tctagaccaa tttaatattc tgacagtcgt
     1981 tttaaacatt gcactaacct cctatattag atacgattga tttcgatttg gctcctatat
     2041 gcgataacca catattttta tataaatcac atttttcaag aagttcatcg tgtgtacctg
     2101 tatcaaatat agttttattt tttaaaacca caattttatc tgcgtttttt atagttgata
     2161 atctatgtgc tacaactatt aaagtcttat tttttgtcaa aacattaata gcaccttgta
     2221 ttttttcttc attatctgga tctataaatg ctgtagcttc atcaagcaat ataataggag
     2281 catttttcaa catcattctc gctatagaaa tcctttgcct ttgtccacct gaaagcttac
     2341 ttccaagact tcccacattg gaattatatc cttcttcaag ttccataata aaatcatggc
     2401 aagcgcaaat ctttgatacc tctataactt cttcgtcact tgcatcagga tttcccatcc
     2461 gtatattttc cataatactt tcattaaata gaaagttatt ctgcgataca taaccaatta
     2521 aatcattaag ttgatttaat gatatatctt taacattttt tccacctatt gtaatttccc
     2581 caccacaaac atcccaatat cttgaaataa gttttattat tgtggatttt cctgaacctg
     2641 atggtccaac tattgcagta aaagaatttt gaggtatttc tatatttata ttctctagga
     2701 cactattttc attatcataa gagaaaaaaa cattattaaa ctttatattt gttgtacaaa
     2761 tatgttcatt attatcgata gaaataagat taggaataca tagaatctca tttatatctt
     2821 ttacagcgta ctctatactt tttaacagat tgacataatt tgtaaattga gtgagaggaa
     2881 ttactattcc aagagaaagc attagacata tgcaaaattc agcaggtgtc agtgttccgt
     2941 ttaaatatag aatcataccc acaggtaatg ttcccaaaaa tgttgatggc aaaatagaac
     3001 ttgcaaaatt cataatactc caagttgatt taaaccaatt caatgtatga tctttgtata
     3061 aatttactgc atctttatat tttttatatg aattactatc ctgattaaaa gtttttataa
     3121 cttctatacc actaatatat tctactattg tagaattcat atacttgtta gatttcattt
     3181 gagcttcata aagctgatta aaattaccca ttagtttttt atatgccatc aaagcaaaag
     3241 gcactgtaat aaacatcgca agagccatct cccaacttat gaagaccata aatattgcaa
     3301 tacctagtga taaaagcaat gcagcaacac actctggtat gatatgtgct agaggcatct
     3361 caattgtttc aactttgtct acaataattg acttatattc tcctattgtc ttttttgacg
     3421 catttcccat agaaatactg agcaattttt cacctaaatt ttctcttata tttcttaaga
     3481 ttgtgtaagc ggatatatga gataatattg ttgatactcc atggcaaata tatctgataa
     3541 aatatgcaat aataccaatc gctccataat acaatacatc ttctccagtt gctttttgtt
     3601 ctataaagac tgccataagt ttatatactg accaataagg tataatgcta aagaacactc
     3661 ctatactagc cataactact gataaaatca actttccttt acaatctgaa gcaaaatcta
     3721 atatagtatt tatccagttt ttgttgctca tgtaacttct ccacctcctt tatctaaaat
     3781 tcataaactc tatcacatat ttcatttata aattctatat cgtgtgaaac cacaaaaata
     3841 tagtaatttt tttcactcaa cttctttagt tcattagaca ctgcaagcat accttcataa
     3901 tccaatcctg atgtcggttc atcaaaaatt aatattttct tatcagataa aatcgcattt
     3961 gcaactacta acctttgttt ttgtccaccg gaaagtatca taggatgtga tttttttgac
     4021 tcaattaatt ttagttcacc caaaacctta tcaatttgta tattatcaca gttatttcct
     4081 aagcaacatt cttctactaa gctatctgca aataactgat aattcacatc ttgcataacc
     4141 attgcagata gcctttgtct ttttttgcca cttataacat caccatttaa tgtaatttct
     4201 ccttttgttt ctttatgtaa tcctgcaata catcgaagaa gtgtagtctt tccaacaccg
     4261 ttatttccta taattcctaa tatttctcca gatcttatgc ttagatttaa atttttaaaa
     4321 actatttttt ctccataaca acaagacaaa ttctta
//
LOCUS       DARYXZ010000088         4333 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYXZ010000088 DARYXZ010000000
VERSION     DARYXZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4333
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(44..754)
                     /locus_tag="TV186_001934"
     CDS             complement(44..754)
                     /locus_tag="TV186_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1533286.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
     gene            complement(1201..2559)
                     /locus_tag="TV186_001935"
     CDS             complement(1201..2559)
                     /locus_tag="TV186_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1533287.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSRYFLLYFPI
                     LGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHK
                     VPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIA
                     VHLINIVSLETASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTF
                     LCHIEVIGFSSVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWK
                     ML"
     gene            complement(2967..3197)
                     /locus_tag="TV186_001936"
     CDS             complement(2967..3197)
                     /locus_tag="TV186_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533288.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(3291..3704)
                     /locus_tag="TV186_001937"
     CDS             complement(3291..3704)
                     /locus_tag="TV186_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533289.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLISGIVSWIYHLYLRKVE"
     gene            complement(3739..3936)
                     /locus_tag="TV186_001938"
     CDS             complement(3739..3936)
                     /locus_tag="TV186_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1533290.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
     gene            complement(4218..>4333)
                     /locus_tag="TV186_001939"
     CDS             complement(4218..>4333)
                     /locus_tag="TV186_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1533291.1"
                     /translation="KTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
BASE COUNT         1353 a          840 c          580 g         1560 t
ORIGIN      
        1 gctagaactc aagccttgga gtgctaagtc atttttctat tctttagtag cccattcgtt
       61 gtgcccatgc cttatcaata gcaagggttt cagtgtctgt atagctcttg cgataaggat
      121 tccagacaga ggtcaaagga gccgcagcaa gcgcttcttg cgcctgatta tttactatat
      181 cataggccgt tagaccgtag gtctcaatga tgttgtttaa tttccagtta tagctagtat
      241 ctgtagcata caagcctgtt aaagctgctg tagcgtcctg ataagacaag gtatttgact
      301 ttctagcacc tgcataaata tctgagctaa gcaaattagt gtaatcatat aaggaatcag
      361 ccactgtcgg ataagctcta aaggtttgat cgatgtagta agtatttcca gccccatcgt
      421 cttcccatgt tgtcatcgtc actgatgacc cattataagc ccctttaatg ccaaaaaaat
      481 tataataagg tgcttgactt aaagctgatt taccgttagc tgactctaaa atagcttgag
      541 caatcataac cgaagcatac aagtctcttt cttgagcaac aacactagca gttgctccaa
      601 tctcttcaat aaaggcttgc gttgacgacg ttgacacagt ctctgctgag acatctgatg
      661 tattttctga ctgtctaatt gaactataaa cacctaagca ggctactaga acaaaaagac
      721 tgataagtgt gagcttacct ttcttttttg ccatttatca ttccctcttt ttttgataaa
      781 tagattatag cacagaatgc tcataaaaag acttatccac aaacaattta atcatattga
      841 taacttttgt ctttaaatcg aaatatttta atgtaaagaa ggcttaccaa gtccataaag
      901 cgaaggcttt tcataatctt ttacgcctta tttgctatat cgccttgtaa tagcttcaat
      961 acctttgaaa ggttattaca cctactattg ttctttatgc ctgtctgtta agtattttcc
     1021 atttaactgc ctttattttt taggtaaaga aaaaacagta aaccattaat ttactgtttc
     1081 ttaattgata tttaatattt tcttataact attgatgtta aataaatgaa aatatatcat
     1141 tcttgtttac taccaacttc taactagtat agtacgagga tataattaaa tcttcgtctt
     1201 ttacaacatt ttccaatata acgctagtgg taacaacaat aataatccaa tagctgatac
     1261 aatcgaacaa tatattgtca ttcttgcttt tgataaattt tcattttgta aaaccaccat
     1321 caagggtggt gcctgaaatg ggaaaaatac acttgaaaaa cctataactt caatatgaca
     1381 taaaaatgtt tttgaaacat tactaacgcc tgaaatatta tcaatcaaag gtgtaactac
     1441 tgccggaaca cccggtaaag ttactataaa tcctaatata atacacaata caacgaaaaa
     1501 agttaaaaca ttaaatgcac ttgctgtttc caaagaaaca atattgatta aatgcacagc
     1561 aatgacattt gcaagtcctg aagattttgc tatattccct aaacttatga ttccagctac
     1621 ataaaaaaat ggctcaaaat ttatttttct taaaggttgc ttttccataa aatttgaatt
     1681 tggtaacatt acaatcaagg cagttgccat tcctgtccaa ccggttggta ctttatgaat
     1741 atgttctgtc atccagaaag acagagttat aaataacaaa actattaaca atttctgctc
     1801 ttttgttatg tcaatggctt ttttggacac gcaaatcgaa tctttacatc ttctataaaa
     1861 taaccgcatt gtaaaatata aaatcaatat ttttccaact cctaaaatag ggaagtacaa
     1921 gagaaagtat ctgctatagg atatatttat ggagtaaaga cttaaaattg ctccagtaaa
     1981 aacattattt ggaacattgg aaggtaatac ataaaatgca ggtatatagg ttgctaaaac
     2041 ccctgacata acaattcctt cccattcctt acttcctttt tcataaccta attctaaaga
     2101 tagggcattt agaataggta aaagcaaaac tactctaccc attgctgatg gcatcaaaaa
     2161 aattagtacc actcctagca aaatcgtccc aaataacact ttagaatatt tccccatgca
     2221 caccggaata aaaaatctcg caagtaatct atcaagttca gtatgcttta ctgccgcccc
     2281 tataataaca cctgaaataa caagccatgc tgcacctgaa gttatccctg ataagatgac
     2341 ttgcttctca gctatattcc ctatcataca agctgtcata aataaaatgc ttgtatacca
     2401 tgcaggaatt atattgcttg ccaaaaggaa gatagatata agaatcaaaa taaaaacttt
     2461 ctctatattt gaaataaatg gtagtacaga tacaaacaac ggtaacattg taaatatcca
     2521 ctttatatga ttattcctaa ttccagattt taaaatcatc ctccattttt gacctccaac
     2581 tctaatttat ttcatagtat tataccatat ttattttcat tttataggtc tacctcttgc
     2641 ttctttgtct gtgttaatcg cttttcttgt ttttataact gctctataca agtcttaact
     2701 ttttctgcct gtttaatttt ttctcgtatc tctaatattt tattgtgtaa gctctttttt
     2761 tctttcttca tattggcgac ttccgatttt catttgctaa tgactaaggt cttgctttcg
     2821 cccaaatgct cttttagata tttcttggca ctctcaaata aaataatctc tgctgtatca
     2881 acgttagctg atatgccctc tgcaagagcc ttcggagaac gcacgcacct gttgaggtgt
     2941 atatgtacac tcttgtaaac aagggactat tcctctgtgt ccgttgcttc ctcttgcact
     3001 tctatgtttt cttctgtttg ttctcttttc tctatgattt ttaggatttt ttgattgact
     3061 gctccctttt cataaaggcg tctatctctc ttttttctct cttcctgttt cgactgaatg
     3121 atgggctttt ttcttttgtt ttgtaactgc ttgatttctc catctgtcat taaaattttt
     3181 tcatctatgt ttttcatttt ctattttcct ctctttctgt tttgagcaac aaaaaaacag
     3241 taaaccattt ttttgattta ctgttttcta ataaatatta tcttagttat ctattctact
     3301 tttcgtaaat ataaatgata aatccatgat acgataccac ttatcaaaac aactccaatt
     3361 atagaaaacc cagaaacttt gtttaaatag cccataaaaa ctagaagaaa aaaaactatt
     3421 cccagtaaag ttgtttgaat cacatatcct accatattag ccttagctgt tattaaggac
     3481 tctctttcat cggtttcatt tatccaatct tgttttttac ctgaaattga aaatacccat
     3541 attccactaa cacacagaag aatagcaaca acgagaaagc ctacccatgc aatatccatt
     3601 cttggaaata cctgtaaaat atctttttta aaaaataata tgcaagcaat caaggcaaaa
     3661 agtattccag tagcaataac tataatagct aactttcttg ccataaccat ctcttttttt
     3721 atatttcttt tcattttttt attcctcctc gtatataaag atatcttcaa tgcttaaact
     3781 aaaatactta gcaattttaa aagctaaaat aatggaagga ttataccttc cgttttctaa
     3841 agaaccaatt gtctgccttg atacttcaag aatagatgct aactcttcct gtgttattcc
     3901 attttctttt ctgatttcct caagtctatt tttcacattt aatgacctcc tgcaacaatg
     3961 acaagctaac tttacatata gtataatgtt ttttagagaa aatggcaagt atactttcca
     4021 taaaatcgtt tccttatagg tctagccctt acttttttac atgtacgact cctctatatc
     4081 tgcattttcc tcttatactt ctgtctgttg atgagcactt gcttctcttt gtgatgatat
     4141 ctttactatg cttttcattt ttgggatttt tatcttaatt ttgagtagtc ataactaatg
     4201 cccgtaaaaa cgggctttta tcttgtttta aaactgccat ctgaaaatgg atcttcatat
     4261 tctttaacac tcaacttatc aagtgcaatg tcatttttct cctgctcgcg aatatatttc
     4321 gctaccgtct ttt
//
LOCUS       DARYXZ010000089         4069 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYXZ010000089 DARYXZ010000000
VERSION     DARYXZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            295..2097
                     /locus_tag="TV186_001940"
     CDS             295..2097
                     /locus_tag="TV186_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1533292.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            2075..2674
                     /locus_tag="TV186_001941"
     CDS             2075..2674
                     /locus_tag="TV186_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1533293.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2782..3708
                     /locus_tag="TV186_001942"
     CDS             2782..3708
                     /locus_tag="TV186_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL1533294.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3701..>4069
                     /locus_tag="TV186_001943"
     CDS             3701..>4069
                     /locus_tag="TV186_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1533295.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILGL"
BASE COUNT         1256 a          754 c          786 g         1273 t
ORIGIN      
        1 gcctgtgccc taaccctctc acctagacgc aaaaagaatc aaaacaaccg ttaataggaa
       61 atcatgaaag ccttctatga cagtcattgt tcataggagg ttttttacac caaatagacc
      121 ttctattggc ttttcatttg attcttaatg gatttttact gctaatttct gactcaccat
      181 cgttgcattc gtctcattat ttacaaattt atttggctaa tattgaaaat atgttatgat
      241 taatgtatta ttttggtatt atttttaaaa aatattattt tagaatggta aaaaatggag
      301 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
      361 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      421 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      481 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      541 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      601 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      661 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      721 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      781 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      841 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      901 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      961 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
     1021 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
     1081 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
     1141 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
     1201 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
     1261 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1321 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1381 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1441 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1501 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1561 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1621 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1681 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1741 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1801 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1861 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1921 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1981 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     2041 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     2101 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     2161 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     2221 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     2281 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2341 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2401 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2461 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2521 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2581 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2641 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2701 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2761 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2821 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2881 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2941 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     3001 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     3061 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     3121 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     3181 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     3241 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3301 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3361 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3421 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3481 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3541 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3601 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3661 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3721 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3781 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3841 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3901 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3961 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     4021 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggactt
//
LOCUS       DARYXZ010000090         3757 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYXZ010000090 DARYXZ010000000
VERSION     DARYXZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3757
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TV186_001944"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TV186_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL1533296.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1245)
                     /locus_tag="TV186_001945"
     CDS             complement(664..1245)
                     /locus_tag="TV186_001945"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL1533297.1"
                     /translation="MCDACQRHFCRITQPTCSNCYQYRHEGACQDCIAWKRQGYQVDH
                     QSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKAYTLVPVPVSKQRYDE
                     RGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNRYRLKKGAALPPKILL
                     IDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TV186_001946"
     CDS             complement(1473..1658)
                     /locus_tag="TV186_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1533298.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TV186_001947"
     CDS             complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TV186_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL1533299.1"
                     /translation="MRIFLRQNCRLVNMSTTFFIVVLSLVVFSVRMVSAEGTINIKDI
                     YSPRWDVDKTLSPTTLREIYNRDTIKKENKPVTGKRGTQVIIDAQHKTKVWEFDDYNF
                     IISSNLYPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIY
                     MNVFIDGHKKDETSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSKVLSGNW
                     EFHGSGENEEGADLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN"
     gene            complement(2835..3626)
                     /gene="spek"
                     /locus_tag="TV186_001948"
     CDS             complement(2835..3626)
                     /gene="spek"
                     /locus_tag="TV186_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL1533300.1"
                     /translation="MRRKNEKNTLALLFLVCVSLTLCTTESVFSDTYNTNDVRNPRNI
                     YAPRYDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKK
                     VISSNLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYIDGGIIKTSDVKPEEKAIY
                     INIFGEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFW
                     DIHYKDGGIRHTNLFTYPDYTDNETIDMSKVSHFDVYLNEEFSKN"
BASE COUNT         1137 a          745 c          541 g         1334 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa ggtaacggga gatttttcaa aagttatttt
     2041 atatttcgag gtctcatctt tcttatgccc atcaataaaa acgttcatgt aaatcgtttt
     2101 tccagctcct tttctctcat taactttaac gagaccacca ttgattgaat gtatttgatc
     2161 ttttgaaaat acttcagccg ataatgcaag accaaaaaca tcgacattat ctccaacatt
     2221 aaatttacct tctacagatg ggtataggtt acttgatatt ataaaattat aatcatcaaa
     2281 ttcccatact ttagttttat gctgagcatc tataataact tgcgtccctc tttttccagt
     2341 aacgggttta ttctcttttt ttatagtatc tctattataa atttctctta aggtagtagg
     2401 ggataatgtt ttatctacat cccaccttgg agagtatata tccttaatat taatagtccc
     2461 ctccgcagaa accatcctaa cagaaaatac caccaatgac aatactacta taaaaaaagt
     2521 agttgacata ttaaccaaac gacaattctg acgtaaaaaa attctcattt atcttattat
     2581 tctccttaat aaatcaatat agctgtgaaa ctatgttttt tgaacttgaa cctcaaaatg
     2641 cttaaatcgg aagtacttga gcagacttct taaaagataa taaactgatt ctataacgca
     2701 cagaaattaa tctgagcggt tttatcatat tcctcggttg accgatagtg atgcctagaa
     2761 gtctactaaa accgtctaat tcatcaaaat ctatttaaat agactaaaaa ttaaattaaa
     2821 atagcattcg accgttaatt tttagaaaat tcttcgttta agtaaacatc aaagtgacta
     2881 actttactca tatcaatcgt ttcattatct gtatagtcgg ggtaagtaaa taaattggtg
     2941 tgtctaatgc caccgtcttt ataatgaata tcccaaaacc cttttttata caaagaatcg
     3001 tactcataca attttatttt gctgtctccc atcaaacttt tcctaagtct aacatcaatc
     3061 tcctgaagag ttacaatatt atttttaaag gtaatcttat ctttagctgt taatgttcgt
     3121 aattcttttt caccaaaaat attaatataa attgcttttt cttctggttt tacatcactt
     3181 gtttttatta ttcccccatc aatataattg aattgttcct tgcatacaac atgatatgac
     3241 tttactatag caaaaatatt cacatgatca ccaacattaa acattctttc ctgtgaagga
     3301 gaaagattac tagatatgac tttcttaaaa gtgttatcat tccaaactgt agtattttca
     3361 tccgtattaa aaatcaattg cgttccttgt ttggcattta tcgatatatt atttttttca
     3421 ataatttctt tattatatat ttcttttaat cttctattat ctaaaatttc gtctttatca
     3481 tatctaggag catatatgtt ccttggattt ctaacatcat ttgtattgta cgtatctgaa
     3541 aagacactct cagtagtgca tagggtaagc gatacacaca caaggaatag caaagccaag
     3601 gtattttttt cattttttct cctaatattt tttaaattta atcaatttac ttagcaagta
     3661 tactatattt aaataataat tcaactataa tttaaaaaaa acaaaaaacc gccctcaatc
     3721 aagagagcgg ttttgtctta tctcggatct ttacctc
//
LOCUS       DARYXZ010000091         3740 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYXZ010000091 DARYXZ010000000
VERSION     DARYXZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3740
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            237..1196
                     /locus_tag="TV186_001949"
     CDS             237..1196
                     /locus_tag="TV186_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1533301.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
     gene            1354..1839
                     /locus_tag="TV186_001950"
     CDS             1354..1839
                     /locus_tag="TV186_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1533302.1"
                     /translation="MIGLVILFIALIILYLGVILFAGATFVKISLFALDKLVVFIASW
                     YYTHHYFSVKFSSGYAIYFWDILAAILVVIIYSILFQFIHKKFRVLGKILNLAISFFS
                     SMIVYCLLVNGFITTEKSYFLPLLNNSFMNQVVNYIIIAIISLVVWKRREDYLVETHD
                     K"
     gene            complement(1949..3322)
                     /locus_tag="TV186_001951"
     CDS             complement(1949..3322)
                     /locus_tag="TV186_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL1533303.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVASD
                     RQQLLDHIKQIEKEMKSIYSVIENKNTISENQLTYDMYIKDKENKAFYEEYKSQIIAY
                     ETAMKSLKNSKLQTLSIKNLSDKYMLLEQEKTTLMGEYSSQNSMLRKLQQAKKNTDLY
                     LDNSLEK"
     gene            complement(3322..3690)
                     /locus_tag="TV186_001952"
     CDS             complement(3322..3690)
                     /locus_tag="TV186_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL1533304.1"
                     /translation="MANRTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILE
                     KDIFVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIY
                     FLRKKLYELGNFGTSGTEEI"
BASE COUNT         1248 a          515 c          635 g         1342 t
ORIGIN      
        1 aaatgaaaaa taaggtatac gaatttaatc aaaaaaaata tccgggttat gaggatatgg
       61 atataaaact aacaatatct actattaagg gtatcgagga tttcgatacc cttaatgatt
      121 tttatgatag tttgaaaagg aagggatatt tagaagcgat aaaagaaagt attaaaaata
      181 ttattgataa agaattagaa gaaaacatac aagtaaaagt acaggaggta aaaaatatga
      241 aattagaaaa aggcgatatt gtaaaaacag cattaagtga aaacacaaca gttttggatg
      301 tgaaagataa tcaggcggta ctgttttcag gtactcagtt tgtacttgca acagggatta
      361 aagaaaacaa ggaaagcgga aaatttgaat gggataatgg gcgatatgca aatgatttaa
      421 aaagcatttc cgatatacaa aacaataatt ttgaaacgat gaaagagacc ttatcttttt
      481 tagcagagta taatcatagc gattttgtca aaggaattct gtctcttgaa acaggaatag
      541 aaaatgagga tactcttgat gctgcttatg ataattatat gaatgataaa attatgggtt
      601 tggttgatga aaaattttat cattatatag atgaaaatga gattgaagca cctgatttag
      661 aaagcgaaat acaggataag aatagtgttt tatccgatga ggaaaatgta aaggaggaca
      721 ataatactac gagtgagaag tcaaatgaaa ataaggaaaa agcaaatact gtaaatatca
      781 atggcaatat tgcttcagat atagacatta aaaatttgac atcgaaagat ggtagagatt
      841 ttactgttgc aagttttgca gttgctgaaa atgacaagga gggaaatgta aaatatacca
      901 actgtttagc ctataacgat aaggtaagta gtgtagaaaa tttgaaaaaa ggagattttg
      961 ttcatgtatt cggaaaagaa aaaatcagtc agggaaagga cggaaaggaa tatacatctc
     1021 ttaaagttta ttctgcaaag ctgttaaaag ccaaagaaca gagcaaaaca aatcaaaatg
     1081 caaaggatgt aaagaaaccg tcagcacttg gcaagttaaa agagtataag gaaaaggcag
     1141 gcgaaaaatc aaaggaacag gtcagtgtca aaaaagataa aaatatagag agataaaatt
     1201 ataaaaatag tgggtaaata gctgataggg ctgtttatcc actatttttc tttgtttttt
     1261 tattagaaat ggaaaaataa aggtttgata aactataaca ggagcgttat attataagaa
     1321 aaagaagatt attttgatag agaggtgaat gatatgattg gattggttat tctttttata
     1381 gccttaatta tactatattt gggagtcatt ctatttgcag gagcaacatt tgtaaaaatt
     1441 agcctgtttg cactggataa acttgtggta tttatagcaa gctggtacta tacccaccac
     1501 tacttttcag tgaaattctc atccggatat gctatatatt tttgggatat tctggcagca
     1561 atattggtag taataatata ttctattcta tttcagttca tacacaaaaa atttagagtg
     1621 ttagggaaaa tcttaaattt agctatttca ttttttagct ctatgattgt atattgcctc
     1681 ctggtgaatg gatttattac aactgaaaaa tcctattttc tgccactttt aaacaacagc
     1741 tttatgaatc aagtggtcaa ttatattata atcgctatta tttctttggt tgtgtggaaa
     1801 agaagagagg actatcttgt agaaacacac gacaaataag aaaatattat tgtgaaatat
     1861 tgtagaaaat atacttttat caatttgaga gcaagtaagg agattattct tacctgaaat
     1921 atgggtaggg ataatctcct tctttttttt atttttcaag gctgttatca aggtataaat
     1981 ctgtattttt ctttgcttgt tgcagcttgc gaagcataga gttttgagag gaatattctc
     2041 ccataagtgt agttttttct tgttctaaaa gcatatattt atcagataaa tttttaatgc
     2101 tcaatgtttg aagctttgaa tttttaagac ttttcatagc tgtttcatag gcgatgatct
     2161 gtgatttata ttcttcataa aaggctttgt tttccttatc ttttatatac atatcatagg
     2221 ttagttgatt ttcagaaatc gtatttttat tttctattac agaataaatg gacttcattt
     2281 ctttttctat ttgctttata tgatccaata attgttgtct atctgatgcc actttcttta
     2341 attttaaatc taattcctcg taggagttaa tacctgattt tctcatttca tttaaggcag
     2401 atgccatagt tttcatatta tgtttacctg cccatacttc atatccctta gatgatttta
     2461 ccttttcatt gtttttcata tctacaatag tatccggttt cttgtaggag cgtttttcat
     2521 aatgatattc ctgattaaca taaatatttt gcttatttga atcttcgatt cgttccttga
     2581 ttctctcttt tgtataatct tcccctaaag tagatgcttt cgctctggta aatcttccct
     2641 tatctctttt atctttatgt cggaaggaaa ggtattttcc tattttgatt tcataaccga
     2701 aatcctccat tgtctttaga aattcctcgt aagttttgga ttttaaaaca gctttatcaa
     2761 tagtaagttg tagtttattc ttccaagagt ttcctttctt aaattcggta tattccatat
     2821 aggttttacc atttgtagag tatctgtttt taaatttttt gtagttttca tcaataactg
     2881 acaagccatt ttctctacat aaatcatcac tgaccgttcg gatttgatga taacttctct
     2941 tattactttg atatgccttt cctgtttcaa agctgacatt gttaaacaga atatgattgt
     3001 gtagatgccc cttgtcgata tgtgttgtaa ggacatattc atactttccc ctcaagactc
     3061 tctcacatag atccagtccg atttggtgtg cctgctcagg tgtagtttct cctggagcga
     3121 aggcttgaat tagatgcctt gccaagattt ttgctttgga attacattct ttttttgtat
     3181 gttcaaattc aagatgggct gttttgggat tgcagccaaa agaggagata aggatttttt
     3241 catcggtttt atcttcattc ataatatagt ctaatgctag ataaagtgtt ttttctatcg
     3301 gatgaatttt tgtaactgcc attagatttc ctccgtacca cttgttccaa aattccctaa
     3361 ttcatatagc tttttacgaa gaaagtagat gtcttttcct tgtttttcca agagcttttt
     3421 caaatcattg atgtcatctt tgtaaattac agcagttgaa tttacccttt ttgcaatctg
     3481 attgatgcta cctgtaatcc ttccgatatt tgtagacatc tccttaaaca ctttcatatc
     3541 cagtacaaaa atatcttttt caaggatgca cttcataata aactgtctta aacttttaca
     3601 accggacagt tcatattttt tattcaaaat ttcaagttca tcatcagaaa gcataaggta
     3661 tattccatta tttcttgttc tgtttgccat agtataacct ccaattcata gatgtattaa
     3721 aagtttacaa aagaaaaaac
//
LOCUS       DARYXZ010000092         3669 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYXZ010000092 DARYXZ010000000
VERSION     DARYXZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3669
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(50..892)
                     /locus_tag="TV186_001953"
     CDS             complement(50..892)
                     /locus_tag="TV186_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1533305.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSDVEGVLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTITYEFIGKTSQGLKYNLSFTLRTAELP
                     FGETKPKDITLSGGSFAYGGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            complement(904..>3669)
                     /locus_tag="TV186_001954"
     CDS             complement(904..>3669)
                     /locus_tag="TV186_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1533306.1"
                     /translation="LKPAITSVFDTINSLIPNAVAAFARLKQSINIDFSPLGASVKEV
                     FALINTVLGDFAHTGELSGQTFDKLKAKIASLAPKVIALWAVMNPASAIATIMPLLSL
                     FGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLSGLPGVFATAAGRGLSVL
                     GTMTSAMSSLVSLALAAIGPAAILGLVVAGFGLINSQFGAQIDQLLNTAVTKGPGIIQ
                     GLVKGITSKIPALIASGTQLIAKFANAITVLLPVIIQAGVQLITSLVKGIGQNATSLI
                     SSAIKIIDSFVGSIMSALPQLISVGMELLLNVVNGIVQNIPLIIQQGQQIIDSFGNSL
                     RANLPSIISNGIAILVNLVQGITQMLPTVLQTATQVITSFVSGIVQFLPQLLQGGIQI
                     IISLVQGIIQNLPQIVQSAVQIIQSLVSGLTQALPQIIAAGIQLVVQLAVALIKGLPQ
                     IISAGIQLITGLGKAMLEAIPNALSGAWEGIKSGFSSMWDQITGKSSTSTAKVSADAT
                     AMALNVGTQTTAMANQANTDTTSMLNSISQNTELANINATSNATQMANNVNAQTGTMS
                     LQGLNDSMSLASGISANMSVANINATTQAQEMASGVNGATSSMNLDAINHTLSLASGV
                     GANMGTASTSATSQAQAMSSGVSNSLASMQSNSTKAASGLSNSVTSEMSSAATSATSS
                     ANRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTAKQSMANLVSAVASGMSR
                     ATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASSAGTIYAIANSIAANVAA
                     TIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLGKAYATAVTDQNWGVNST
                     VSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVGDKIYTAVKEKESREQSK
                     DSYFVFA"
BASE COUNT         1065 a          819 c          709 g         1076 t
ORIGIN      
        1 ccccatactc aatgtcacga tgatccaaaa aagtaatcat tagaccctcc tatttataca
       61 actctacaaa atttaaaatc ctaatcgtgc caagaaaatc cgttttgtaa gtaattctct
      121 tgttaggatt aggattgaag ataaaatact catagttcgt tttagcattg acataatttc
      181 cgtttagtgt ggtagctatg cctgtcaaaa gtaatttatc actattttgt agctggctat
      241 tctgcttaaa ctcaaagcgc ctgccatcaa tttcaatata aaaattagtc tgacctccag
      301 agggagtaag ctctataata aaaggccact ctaactgact tgctttagcg gttcctccat
      361 aggcaaaact gccccctgat agagttatgt cctttggttt tgtctcaccg aaaggtaatt
      421 cagcagttct tagtgtgaag gaaagattat attttagtcc ttgactggtt tttcctataa
      481 attcataagt gatagtgtcg tctaagatga ctttaaatct atatttccaa ggtttatgag
      541 gagagccaat aagttgcagg tctcctgtgc tttcccctgg aagctcaaag ttaaatagat
      601 ctgagttttc agggtacatc ttagtcacgt agaaaggttc gtcaacaaca agcagagcgt
      661 ttagttcgtc ctgtttgtcc aaaactcctt ctacatcgct taccgtcact cttcctttga
      721 ccttaagcgt tttagtcgta aaagtagccc catcgtagat gtaaccactc cttcctttga
      781 ctgctcggtg tgatacagat agtagaggag cactatcttc aatagcaata ttataaatac
      841 caaagtcaga caatctagtt gcctgactct ctttttctat taataaatcc aaaatactcc
      901 cttctaggca aaaacaaaat aagaatcttt agattgctct cttgattctt tttctttaac
      961 agccgtgtaa attttatctc caacaatctc attatgcact tcaaagatag gctctgacaa
     1021 ttgagactgc ctaacctctt cgctaagatt atcaagagag gtattgattc cactattatt
     1081 aactttagca gatgttgaaa cagtactatt taccccccag ttttgatcag taactgctgt
     1141 tgcgtatgct ttacctagac tattgatctc acctatccac tctgccatac cgagggcaaa
     1201 cccctctcca gtaaatgctc ctagtgtttt agtgacacga gatggcgagt gaatatccag
     1261 agcgcgtcta attgttgctg ctacgttagc ggcaatgctg ttagctattg cgtagattgt
     1321 gcctgcgcta ctagctagac cattagcaaa accttgacct gcataagctc ctgcagaaga
     1381 catctgccct gccaaagccc tgaatattga gaggatcttc tgacaagcat tattagacac
     1441 cgcggttgca cgagacatcc cagaagccac tgcacttaca aggtttgcca tagattgctt
     1501 tgcagtactg ttaatgctac taaatcctgt tttaaccgca ttggctatcc cattcattga
     1561 ggttgttgct gaagtcttcg ccttattgaa gccagactcg accgccgagg acaacctatt
     1621 ggcgcttgag gttgcagagg ttgctgcaga agacatttca cttgtcacgc tattagacag
     1681 accagaggct gctttagttg agtttgactg cattgatgcc agactgttac tcactcctga
     1741 gctcatagct tgcgcctgag aagttgcact tgtgctagcg gttcccatgt ttgcaccaac
     1801 accactagct aagctgagcg tatgattaat ggcgtctaga ttcattgaag aagtcgcacc
     1861 attaacccct gaagccattt cttgagcctg agtagtagcg ttaatattag ccacagacat
     1921 attagcgcta atgccactcg caagagacat tgaatcattc aacccctgaa gactcatcgt
     1981 tcctgtctga gcattaacat tattagccat ctgtgtagca tttgatgtag cgtttatatt
     2041 agcaagctct gtattttgac taatgctatt aagcatagat gtcgtatctg tattggcttg
     2101 attagccata gctgttgttt gagtaccaac attcaaggcc atggccgtgg cgtccgcaga
     2161 gactttagct gtacttgtgg aactcttacc tgtgatttga tcccacatcg aactgaatcc
     2221 gctcttaata ccttcccaag ctcctgaaag agcatttggg atagcctcta acatggcttt
     2281 accgagtccc gtaattaatt gaatacccgc agaaataatc tgtggaagtc cctttatcaa
     2341 ggctacggct agttgtacaa caagctgaat gcccgctgcg ataatctgag gcagagcttg
     2401 cgtcagtcca gaaactaaag actgtataat ctgtacagca gattgtacaa tctggggtag
     2461 attttgaata atcccctgca caaggctaat aatgatttga atgccacctt gaagtaactg
     2521 cggtaaaaac tgtacaattc cagatacaaa actcgtaata acttgagtag ctgtctgcag
     2581 aacagttggc aacatttgag taattccctg tacaagattc accaaaatag ctataccgtt
     2641 gctaataata ctaggaaggt tagcccgtaa gctgttccca aaactatcaa tgatttgttg
     2701 gccttgctgg ataataagag gtatattttg aactatgccg ttgacaacat ttaataatag
     2761 ctccattcca acagaaataa gttgcggcaa ggcactcata attgagccaa caaaactatc
     2821 aatgattttt attgctgaac taattaaact tgttgcgttt tgtccaatac ctttgacgag
     2881 gctggtaatt agctgaacgc cggcttgaat tataactggt aataacactg tgatagcatt
     2941 tgcaaattta gcaatcaatt gagtaccact agctattaaa gctggtattt tagaagtaat
     3001 cccttttaca aggccttgaa taataccggg accttttgta actgcggtgt taagtagctg
     3061 gtcgatttgt gcgccaaact gactattaat caaaccaaat cctgccacca caagacctag
     3121 aatagcggcc ggtcctatgg ccgccagtgc taaactcaca agactagaca ttgcgcttgt
     3181 catagttcca agcacagata gcccacgccc tgctgcggta gcaaaaacgc caggtaatcc
     3241 gcttagagtt gccgcaaagg caccaacaac gccgctggca ctagctatcc cactagaaat
     3301 tatgccacca aacgccccga cagaagtccc taaacttcct aaagctagac caacttttcc
     3361 gaatagagaa agcaaaggca ttatcgttgc tatagcgcta gcagggttca tcactgccca
     3421 aagggcaatg actttagggg ctaaagaagc aatttttgct tttaacttat caaaagtctg
     3481 tcctgataat tcaccagtat gtgcaaaatc tccaagaaca gtattaataa gagcaaacac
     3541 ctctttaacg ctggcgccta atgggctaaa gtcaatattg atagactgtt ttagcctagc
     3601 gaatgctgca actgcatttg gaataagaga attaatcgta tcaaaaacgc tggttattgc
     3661 gggcttcag
//
LOCUS       DARYXZ010000093         3669 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYXZ010000093 DARYXZ010000000
VERSION     DARYXZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3669
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(50..892)
                     /locus_tag="TV186_001955"
     CDS             complement(50..892)
                     /locus_tag="TV186_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1533307.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            complement(904..>3669)
                     /locus_tag="TV186_001956"
     CDS             complement(904..>3669)
                     /locus_tag="TV186_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1533308.1"
                     /translation="LKPAITSVFDTINSLIPNAVAAFARLKQSINIDFSPLGASVKEV
                     FALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWAVMNPASAISTIMPLLSL
                     FGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLSGLPGVFATAAGRGLSVL
                     GTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQIEQLLNTAVTKGPGIIQ
                     GLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQLITSLVQGIGQNATNLI
                     SSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIPLIIQQAQQIIDSFGNSL
                     QANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFVSGIVQFLPQLLQGGIQI
                     IISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAGIQLVAQLAVALIKGLPQ
                     IISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQITGKSSTSTAKVSADAT
                     VMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATSNATQMANNVNAQTGTMS
                     LQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATSSMNLDAINHTLSLASGV
                     GANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLSNSVTSEMSSAATSATSS
                     VNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTAKQSMANLVSSVTSGMSR
                     ATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASSAGTIYAIANSIAANVAA
                     TIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLGKAYATAVTDQNWGVNST
                     VSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVGDKIYTAVKEKESREQSK
                     DSYFVFD"
BASE COUNT         1068 a          828 c          706 g         1067 t
ORIGIN      
        1 ccccatactc aatgtcacga tgatccaaaa aagtaatcat tagacctccc tatttataca
       61 actctacaaa atttaaaatc ctaatcgtgc caagaaaatc cgttttgtaa gtaattctct
      121 tgttaggatt aggattgaag ataaaatact catagttcgt tttagcattg acataatttc
      181 cgtttagtgt ggtagctatg cctgtcaaaa gtaatttatc actattttgt agctggctat
      241 tctgcttaaa ctcaaagcgc ctgccatcaa tttcaatata aaaattagtc tgacctccag
      301 aaggagtaag ctctataata aaaggccact ctagctgact tgctttagcg gttcctgcat
      361 aggcaaaact gccccctgat agagttatgt cctttggctt tgtctcaccg aaaggtaatt
      421 cagcagttct tagcgcgaag gaaagattat attttagtcc ttgactggtt tttcctataa
      481 attcataagc gatagtgtcg tctaagatga ctttaaatct atatttccaa ggtttatgag
      541 gagagccaat aagttgcagg tctcctgtgc tttcccctgg aagctcaaag ttaaatagat
      601 ctgagttttc agggtacatc ttagtcacgt agaaaggttc gtcaacaaca agcagagcgt
      661 ttagttcgtc ctgtttgtcc aaaagtcttt ccacgttgct taccgtcact cttcctttga
      721 ccttaagcgt tttagtcgta aaagtagccc catcgtagat gtaaccactc cttcctttga
      781 ctgctcggtg tgatacagat agtaaaggag cgctatcttc aatagcaata ttataaatac
      841 caaagtcaga caacctagtt gcctgactct ctttttctat taataaatcc aaaatactcc
      901 cttctagtca aaaacaaaat aagaatcttt agattgctct cttgattctt tttctttaac
      961 agccgtgtaa attttatctc caacaatctc attatgcact tcaaagatag gctctgacaa
     1021 ttgagactgc ctaacctctt cgctaagatt atcaagagag gtattgattc cactattatt
     1081 aactttagca gatgttgaaa cagtactatt taccccccag ttttgatcag taactgctgt
     1141 tgcgtatgct ttacctaggc tattgatctc acctatccac tctgccatac cgagggcaaa
     1201 cccctctcca gtaaatgcac ctagtgtttt agtgacacga gatggtgagt gaatatctaa
     1261 agcgcgtcta attgttgctg ctacattagc ggcaatgctg ttagctattg cgtagattgt
     1321 gcctgcgcta ctagctagac cattagcaaa accttgacct gcataagctc ctgcagaaga
     1381 catctgccct gccaaagccc tgaatattga gaggatcttc tgacaagcat tattagacac
     1441 cgcggttgca cgagacatcc cagaagtcac tgaacttaca aggtttgcca tagattgctt
     1501 tgcagtactg ttaatgctac taaatcctgt tttaaccgca ttggctatcc cattcattga
     1561 ggttgttgct gaagtcttcg ccttattgaa gccagactcg accgccgagg acaacctatt
     1621 aacgcttgag gttgcagagg ttgctgcaga agacatttcg cttgtcacac tattagacag
     1681 accagaggct gctttagttg agtttgactg cattgatgcc aggctgttac tcacccctga
     1741 gctcatagct tgcgcctgag aagttgcacc tgtgctagca gctcccatgt tcgcaccaac
     1801 accactagct aagctgagcg tatgattaat ggcgtctaga ttcattgaag aagtcgcacc
     1861 attaacccct gaagccattt ctcgagcctg agtagtagcg tttatattag cgacagacat
     1921 attagtgcta atgccactcg caagagacat cgaatcattc aacccctgaa gactcatcgt
     1981 tcctgtctga gcattaacgt tattagccat ctgtgtggca tttgatgtag cgtttatatt
     2041 agcaagctct gtattttgac taatgctatt aagcatagat gtcgtatctg tattagcttg
     2101 attagccata gctgtcgttt gcatcccaac attcatggcc atgaccgtgg cgtccgcaga
     2161 gactttagct gtacttgtgg aactcttacc tgtgatttgg tcccacatcg aactgaatcc
     2221 gctcttaata ccttcccaaa ctcctgaaag agcgtttggg atagccccta acatggcttt
     2281 accgagcccc ataattaatt gaatacccgc agaaataatc tgtggaagcc cctttatcaa
     2341 ggctacggct agttgcgcaa caagctgaat gcctgctgcg ataatctgag gtagagcttg
     2401 cgtcagtcca gaagctaaag actgtataat ctgtacagca gattgtgcaa tctggggtag
     2461 attttgaata atcccctgca caaggctaat aatgatttga atgccacctt gaagtaactg
     2521 cggtaaaaac tgtacaattc cagatacaaa actcgtaatg acttgagtag ctatctgcag
     2581 aacagttggc aacatttgag taattccctg tacaagattc accaaaatag ctataccgtt
     2641 gctaataata ctaggaaggt tagcctgtaa actattccca aaactatcaa taatttgctg
     2701 ggcttgctgg ataataagag gtatattttg aactatgccg ttgacaacat ttaataatag
     2761 ctccattcca acagaaataa gctgcggcaa tgcactcgca attgaactaa caaaactacc
     2821 aatgattttt attgctgaac taattaaatt cgttgcattt tgtccaatac cttggacgag
     2881 actcgtaatt agctgaacgc cagcttgaat tataactggt aataacactg cgatagcatt
     2941 tgcaaattta gcaatcaatt gagtgccact agctatcaaa actggtattt tagaagtaat
     3001 tccttttaca aggccttgaa taatgccagg accttttgta actgcggtgt taagtagctg
     3061 ctcgatttgt gcgccaaact gactattaat caaaccaagt cctgccacca caagacctag
     3121 aatagcggcc ggtcctatgg ccgccagtgc taaactcaca agactggaca ttgcgcttgt
     3181 catagttcca agcacagata gcccacgccc tgctgcggta gcaaaaacgc caggtaatcc
     3241 gcttagagtt gccgcaaagg caccaacaac gccgctggca ctagctatcc cactagaaat
     3301 tatgccgcca aacgccccga cagaagtccc taagcttcct aaagctagac caacttttcc
     3361 gaatagagaa agcaaaggca ttatcgttga tatagcgcta gcggggttca tcactgccca
     3421 aagggcaatg actttaggag ctaaagaagt gatttttgct tttagattat caaaagcctg
     3481 ctctgataat tcaccagtat gtgcaaaatc tccaaaaaca atattaataa gagcaaacac
     3541 ctctttaacg ctggcgccta atgggctaaa gtcaatattg atagactgtt ttagcctagc
     3601 gaatgctgca actgcatttg gaataagaga attaatcgta tcaaaaacac tggttattgc
     3661 tggcttcag
//
LOCUS       DARYXZ010000094         3256 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYXZ010000094 DARYXZ010000000
VERSION     DARYXZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3256
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1556)
                     /locus_tag="TV186_001957"
     CDS             complement(<1..1556)
                     /locus_tag="TV186_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533309.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSVTFPEAANTYNGA
                     VLVVKDMETLKDIQDSIQSINHTGGRASISAYADLTKADLRSISDDKGIISDGDTVIG
                     HIETKKEYLRS"
     gene            complement(1559..2311)
                     /locus_tag="TV186_001958"
     CDS             complement(1559..2311)
                     /locus_tag="TV186_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533310.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2642..3121
                     /locus_tag="TV186_001959"
     CDS             2642..3121
                     /locus_tag="TV186_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL1533311.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT         1036 a          605 c          610 g         1005 t
ORIGIN      
        1 gatcggaggt attccttttt agtttcgata tgacctataa cagtatcacc atcactaatg
       61 attcccttat catcactaat actcctaaga tcagccttag ttaaatcagc ataggccgaa
      121 atgctggccc ttccgccagt atgattaatg ctttgaatgc tatcttgaat gtcctttagt
      181 gtttccatat ctttgaccac aagaactgca ccattataag tgttagctgc ctctgggaag
      241 gttactgatg ttaaattttt gacattggta tatgatttgc ccaaaatatc cagctgtcgt
      301 aattgactat cccctctttg cttaaagaag gcagtctgat tgtcctttaa ttcaggcaat
      361 tgattgccca aggcgcggaa atcatcttga gtgactaagt agacatagcc tgtagtgact
      421 ggactaggat ttagcaagga ttctttggtt actacaatgg tttctttttg ggatacttca
      481 aaagaaacca tgctactata atagactaga aaatccgagg caggcttatt ggtcttttca
      541 acaataagtc tgttaaaaac ctctttttga ttgtcaatct ctgaattatc aaaattaata
      601 tgagtatttt taggaaaaag ctggttagac attgcctcgc tattagcata aagcgcagtt
      661 gttgttgcta ttgcaacaaa ggccataaca gctaagaggg taatatttgc caagcctaca
      721 gcattttgct tcattctaaa aatcatctga gaggtgctga caaaatgctc tggctggtaa
      781 aaataagcct tgttttgacg acgacgcttt aagtgccaag tcataaagga aatgtaaaag
      841 agataggtcc cgataataac gataataact gctataaaaa accgatataa agtgtctaat
      901 gctgtcagct ttgtcgatga taaggagatg taatagccaa tactaagcaa tatgatggat
      961 aaggctgcta gtaataaatt accctttggc tctttttcac cctgttcttt atgacgaaag
     1021 agcattaagg gagaggtctt tctgatttta atcaagccaa caacctctaa taaaccaaag
     1081 atagcagcaa agattaaagt ggtgtaaata aaagcaacgg gattgatttg taattctaaa
     1141 tggactgctc cgaccagatt agcgaaaatc aaataaaaga cgtgtgaaaa aatagctgat
     1201 aggatacttc ctacgactac tgtccctaag tacataaaaa caagctcgat cgttgagact
     1261 aaaccaacct gctttttatt cattcccaaa atattgtaca gaccaaattc tcgacttctt
     1321 tgctttagta aaaaattata gctataaatc tccataatag tggcaaagat gattaaaaca
     1381 aagattgcta gtcctaatag cataaaccca tgtctcatcg attctgatac ggggctcatc
     1441 atgataatca agacaataca attgagcata tataaaacag tgcttgccag taaaaaagga
     1501 gctgtgacgg ataaggactt tcgtagatta ttccaagcta gtttgagata aaacatcttt
     1561 attcacctcc taaaagaccg gccatggcaa tcgagatgtc tttgctaaat tctaaattcg
     1621 ttttatttcc acgatagatt tggtggaaaa tacggccgtc cttgataaac agtactcgct
     1681 tagcatggct agcagcattg gcagagtgtg ttaccatcaa gagtgtctga ccgtctaggt
     1741 taatggcctc aaaaagattg agaatatcct ctgaattgcg gtaatcaagt gctgctgttg
     1801 gttcgtcagc taataataat tgcggattgg tgattaagct tcttgcaata gcaacccttt
     1861 gcttttgacc accagaaatt tcaaatggac gtttatctaa aagcgtttca atgcgcagct
     1921 taggggcaat gatgttgagc cgtctttcca tttctttaaa tggcttacgg tttaaaacaa
     1981 ggggtaaaaa gatattatct ctgatcgata gggtgtctag gaggttaaaa tcctgaaaaa
     2041 caaagcctag gttttgaagt cggaaattag ctaggtcacc ctccttaatt tttgtaatgt
     2101 cagtgccatt caataaaaca gatcccttgg ttggtttttc cagagttgcc agaatattta
     2161 atagggttgt tttccctgag cctgactctc ccatgatggc aataaactca cccttgtcaa
     2221 ccttaaaatc aacatcttgt aaggctctag tttcttcctt tgaaaagcgt gtccgaaaaa
     2281 ccttctctaa atgattaatt tctaataaca tatgaaactc ctttgtgtct attatactct
     2341 tttagcttta aatatagcca ctatcgtgac gtatttagct agtgatgcat ttagtgcctt
     2401 ttgtcagcct taaccactcc ttctttcatg aagcagccca gctctcaaca agaatcgtct
     2461 tagctgactg aacctattgc tctaaactct tttttcttta cagcttatag tttaccctaa
     2521 ttaatagtct ggttagctta caagatttga tgggtgactt acagatttgt aagttttata
     2581 acatcatttt tcttatcatt ttgatataat gaaaggagaa ttctatttag gagaagcgtc
     2641 aatggctaag aaaatcaaaa aaacgctagg gactgtcgga aagctgtttt ccattatccc
     2701 tgataccact gaaattatag gaaaaacgat agataacacc cgtcccatta tcgaaaagca
     2761 tatggaacaa aagcatgaaa aggaaatgca gctaacgctt ttagatgatg tgattaattt
     2821 acctgttgat aaagcgcaaa agcatctgga acagctaggt tttgttgtcg cactattgcc
     2881 ggtcaagcct agtaaaaaat ggatacatgc tagcttaaat gaggttgttt ccatgtcacc
     2941 taagcctgga aagcataagc tgggaagctt agtaaagctt tattatgtta ctgtagatgt
     3001 ccttgagaaa agtcaggcta ttttagatca agagacccta aaggctgtcg aacgaaatca
     3061 aaaaatcgct gataccatcg aagctgttaa gcaaatcaag cttcctttta aaaagagata
     3121 aggctatact gtaaaaaata agctgatacc gttaggatca gtttattttt tatgttgtga
     3181 ctttaagtct atctcgctta gcaggtgcca aacaaataaa ccacccgtta tgtaccgacc
     3241 ttcaatggtt aaagtt
//
LOCUS       DARYXZ010000095         3233 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYXZ010000095 DARYXZ010000000
VERSION     DARYXZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3233
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1037)
                     /locus_tag="TV186_001960"
     CDS             complement(<1..1037)
                     /locus_tag="TV186_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL1533312.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
     gene            1354..1881
                     /locus_tag="TV186_001961"
     CDS             1354..1881
                     /locus_tag="TV186_001961"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL1533313.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
     gene            1878..2270
                     /locus_tag="TV186_001962"
                     /pseudo
     CDS             1878..2270
                     /locus_tag="TV186_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(2377..>3233)
                     /gene="galU"
                     /locus_tag="TV186_001963"
     CDS             complement(2377..>3233)
                     /gene="galU"
                     /locus_tag="TV186_001963"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL1533314.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDLTDYIIKLGKAL
                     ESTQQQTK"
BASE COUNT          818 a          696 c          744 g          975 t
ORIGIN      
        1 ttccctaact tccgttcacg gatataagat ttcttagcga aggtaagttc tgggttaaat
       61 tgccaatccg atgaatcaag gatgtgttct tgaatatctt ttggagctcc tcggcgtccg
      121 cgatgtttct gtgagaagag ccagccatct tcttgcttga gcatttctga aacattagcc
      181 atactattca tcgccttatc ggcgactaca attaaccgct caattccaaa ttgttttttg
      241 acttcctcaa ccgctggaag ataggtaaca ggatcggttt gattacctcg aaacagttta
      301 tagctaatcg gaataccgtt ggtatcccta aagagtccta attgcacaat gggttttgga
      361 cggtgttcct tactcggacc acgtcttcga agcccttctt gtagtatctc tccattttct
      421 gaaaccaact cgttatctgg aatatctgtc tcaaaataat aattggtgac atcgtagaaa
      481 acgagactgg cttcacgttt gatcatctga ctcactacct tgtgaagatg atgttgaaga
      541 tcatctttca aggtgttcaa tttgttcaag gagcgataaa tggcatttaa gctgatgtcc
      601 caatggccaa ataagtctgc ttgagaggca taggtggcaa gtttactatc tggtcggaga
      661 attctctgaa aaactaatag ctttagcact tgcactaagt catactcaga cttcgttttg
      721 atacccttta aaaaggctgt gagccccaga gattcgaaga gattatccaa aaccatccaa
      781 ccataagatt gatccggttg gttcatgggg gcaaggaggt cataggaaac ctggagtacc
      841 ttagggttat ttaaagtatc ttctttagct tcgcgcttaa gacgctcaag aatccctggt
      901 tcttccaatt caagctcatc taagagacca aattttttaa ggatacgctg tttgacctta
      961 ccatctttac gatacccttc tacaaggtag acatgcgtcc taccttcttt attcgttgtt
     1021 gttttaataa aagccatagt ttattataac atatataacc atacacaaca agaaaaagcg
     1081 ttaaaattta ttaaaaaaac cttactctac caaggggttg agtaaggtgt ggactaaaac
     1141 aagtgataaa gtcgggtgta tagcataaag cttaaacttt tcttaaccta gaaaaataat
     1201 tttttgatct catgagacca caagctcacc tcaagaagta agaaggacat tcactgattg
     1261 agctgctgcc ctgtctggta ggacaactaa ggaaagaacc ttgattgtgg ccgattcttg
     1321 aatagtagca gcgctttgtg ttatgatatg ggcatgatta aaaaagatta tcgccaacta
     1381 gtgcttcagc gcctagccat gatgacccca gaggataagc tggaaaagga cttagctcta
     1441 ttggcagcag tagttgctag tagcagctat caagaggcgc agactcttgt gacctatctg
     1501 cccttgccac acgagtatca aagccatcta ctgattgagc gagccttgca ggacggcaag
     1561 actatccttg tgcccaagac tcgttctcgt ggagagatgg tgtttgtggc ttatgatcct
     1621 tgtgacttga tacagacggc ttttggtctt atggagccta ggtgtaccat agctgttgct
     1681 aagtcggaga ttgatgccat tcatgtgcca gggcttgttt ttcaccctgc aggctatcgt
     1741 ataggctatg gtggtggcta ctatgatcgt tatttgaggg attatcaggg ggctaccttt
     1801 agcacgattt atgcctgtca gtgggaggat tttgtggtag aggcacatga tattgctgtg
     1861 aaggaggtgt attgccaatg agactgatga tcaaaaaata cccgataaca ctctttttct
     1921 tgggcttgac tggtttagtt tttttgataa tgcagctggt ctatggccag tttgctacgc
     1981 acccttatgc tgttgttata tttggtggca tgaatggtct tgttgtcaga gcaatgcctg
     2041 atcagctttg gcgcttggtg acacctatag tggttcatat tggctttgag cattttttca
     2101 ttaatacctt aaccctttat tttgtcgggc ggatggctga gaccatttgg gggtcaagac
     2161 agtttttgct gctgtatgtg tgttcaggga ttatggggaa tgcttttatc atgtggctga
     2221 caccagatac cgtagcagca ggtgcttcca cctctctttt tggtcttttt ccttcaagct
     2281 tataagtgct aggacaggtg tatctttgat ttaaacaaaa agcaacggtt ttgctgctgt
     2341 tgctttttaa tgcttctagg acggttgccc caactcctat tttgtctgct gttgagtgct
     2401 ttctagtgct ttacccagct ttataatgta gtcagtgagg tcgtccttga cctgagggtg
     2461 cttgagagca tagtcaagtg aggtcttcat aaagccaaac ttgtccccaa catcataccg
     2521 ctctccctta aactccctgg caaaaacccg ctgagtcttg ttgagcttgt caatcgcatc
     2581 ggtcagctga acctcattgc cagccccagg cgcctgattc tccaatatgg caaaaatctc
     2641 aggcgtcaac aaataacgtc caataatcgc taagtcacta ggtgcctcat caggacttgg
     2701 cttctcaaca aaggtctcca cactatacaa gcccttaaca gccttccctt gcggtgcaat
     2761 cacgccataa ttggaaacct cctcatgcgg aaccctcatc acagcaatcg ttgaggcgtg
     2821 tgtacagtca taatcctcga taagctgctt ggtcaagggc ttggcactag gattggtaat
     2881 atccatgagg tcgtctccta gcatgaccac aaagggctca ttgcccacaa aggccttggc
     2941 ttggaggaca gcgtccccta gtcctctagg gtggctctga cgaatgaagt gcaggttgat
     3001 ggcagtggtc tcatcaacga gcttgagcag ctcggttttg cccttggctt ggagattgta
     3061 ttcgagctcg aagttggagt caaagtggtc ttcgatagag cgtttggcct tgccggtgac
     3121 gacaagaatc tcctcgatac cggcctttag ggcttcctcg acgatgaatt gaatggttgg
     3181 cttatcgacg attgggagca tttccttggc cagtgcctta gtggcaggca gga
//
LOCUS       DARYXZ010000096         3091 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYXZ010000096 DARYXZ010000000
VERSION     DARYXZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3091
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(1..234)
                     /locus_tag="TV186_001964"
     CDS             complement(1..234)
                     /locus_tag="TV186_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HEL1533315.1"
                     /translation="MVFDYSKLSGRIVEKFGTQYNFALALGLSERSLSLKLNNKVDWR
                     SKEIAQACQELDINENDVGEYFFKQNVHIHEQN"
     gene            442..1209
                     /locus_tag="TV186_001965"
     CDS             442..1209
                     /locus_tag="TV186_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1533316.1"
                     /translation="MSERNLRQVDILEKSKPFQKQLGVKMGRSTLSQYVSGKSVPAQR
                     QLYLLSKTLNVSEAWLMGYDVAIERIPDEKRRATTEISNQPEIVSIYNQLEQPRQEKV
                     LSFANEQLEEQNKVVSTHEELFSVQGVTYAAAASGFGRGFEADEYDTYTVYTDEEPPR
                     YDYAIGIRGDSMLPKYEQGDMLYIVDRGMSTYNGQLCIVVHNGQTYFKKVYTEEDGLR
                     LVSLNKKYNDIFIDYPPAEDTYIKIYDVVGSFTPVEM"
     gene            1223..1453
                     /locus_tag="TV186_001966"
     CDS             1223..1453
                     /locus_tag="TV186_001966"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533317.1"
                     /translation="MTTFTLTIDEKNKYIADYFKRNNIDDSQLTFEQLLTVLEDAEDY
                     AAGMAVLMEQKDNPDYKTYTLQEVADELGITL"
     gene            1453..1740
                     /locus_tag="TV186_001967"
     CDS             1453..1740
                     /locus_tag="TV186_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1533318.1"
                     /translation="MYKIEFDPKVKKQLKKLDKTASSKIIRWLYANVDGTSLPRLHGK
                     ALTGDLAGLWRYRIGDYRVICDIQDDKLVILAVHIAHRKQVYKLKLPNNKR"
     gene            1753..2079
                     /locus_tag="TV186_001968"
     CDS             1753..2079
                     /locus_tag="TV186_001968"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533319.1"
                     /translation="MYFDEFKEYVENNSRAHDYFFERALDYQNAKNARRTPAHRRWKE
                     QKVLKEVETMWTNVVKQLYDNIKLNGKFRKRFMHQEEIDEWVSFMNEHEILESFADSM
                     AEIEFE"
     gene            2145..2570
                     /locus_tag="TV186_001969"
     CDS             2145..2570
                     /locus_tag="TV186_001969"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533320.1"
                     /translation="METEKINNVNILRSNNSRLSGYATSASYPLILPIIVEFELYNIK
                     QSKTYLFQITATKINDRRQNNHIKDLLSLSSNQTTVTISAERHNTFFPYEGYGTVATK
                     LDFSFNIDSPGDYCIALTLLDSEGSLLDKHSNYYIFGEE"
     gene            2672..2938
                     /locus_tag="TV186_001970"
     CDS             2672..2938
                     /locus_tag="TV186_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533321.1"
                     /translation="MSQEIYSKSEIDLKFENLETKIDSKFDLLMQKMDDGFEKQRLNT
                     EKMLSDFKLNLVTDQQKNKKEFMYWAIGIIIALAGIAFPIWFGK"
BASE COUNT         1102 a          530 c          578 g          881 t
ORIGIN      
        1 ttagttttgt tcatgaatat gaacattttg cttaaaaaaa tattctccta catcgttttc
       61 gttgatatct aactcttgac aagcttgcgc aatttctttg cttctccagt ctactttatt
      121 attaagtttt aaagatagcg agcgctcaga tagccctaaa gccaaggcaa agttgtactg
      181 tgtgccgaac ttctcaacga tccttccgct gagttttgaa taatcaaaaa ccataggaac
      241 ctcctttctt ttttgttcat gttcatgaac tttatgcttt tatgttacac tttgttttga
      301 actttgtcaa tacacaaagt tcattttttt gaattttttt attgaacttt tgttcaagat
      361 gttttataat taacctataa acatcgaaag gaatctactt ttatgcaatg tagttctact
      421 tcaaatagat taaaacaact gatgtcagaa agaaatttaa ggcaggttga tattttagaa
      481 aaatcaaaac cttttcagaa acaattgggg gtaaagatgg gcagaagtac tctttcgcaa
      541 tacgttagtg gcaaatctgt tccagctcaa cgacaactct atcttttatc taaaaccctt
      601 aacgtaagcg aggcatggct gatgggatat gatgtagcca tagagcgcat acctgatgaa
      661 aaacgtagag ctacgacaga aatatctaat caacctgaaa tagtgtccat ctacaaccaa
      721 ctagaacaac ctagacaaga aaaagtcctc agcttcgcta acgaacaatt ggaagaacaa
      781 aataaagttg tttctacgca tgaagaatta ttttcggttc aaggcgtaac ttacgcggca
      841 gccgcaagtg gctttggtcg tggatttgaa gcagatgaat atgacacata tactgtctac
      901 actgacgaag aacctcctcg ctacgactac gctattggaa ttcgaggaga cagcatgcta
      961 ccaaaatatg agcaagggga tatgctctat attgtagata gaggtatgtc aacatataac
     1021 ggtcaactgt gtatcgttgt tcacaacgga caaacctatt ttaagaaagt atatacagaa
     1081 gaagacggac ttagattagt atctctcaac aagaaatata acgatatttt tattgactac
     1141 ccaccagcag aagatactta tatcaaaatc tatgacgttg tcggcagttt tacacccgta
     1201 gaaatgtaaa ggaggagata ttgtgacaac atttacactt acgattgatg aaaaaaataa
     1261 atacatagct gactacttca agagaaataa tattgatgat agtcagctca cgttcgagca
     1321 gctccttact gtcctagaag atgcagaaga ctatgcggca ggtatggcag tgttgatgga
     1381 acaaaaagac aatcccgact ataaaaccta cacacttcaa gaagtagctg acgaattggg
     1441 tattactcta tgatgtacaa aatagaattc gaccctaaag tcaaaaagca gctaaaaaaa
     1501 ttagataaaa cggcatcttc aaaaattatc cgttggcttt atgctaatgt ggacggtact
     1561 tctctaccta gactgcacgg aaaagcgtta actggtgacc tagctggatt atggcgctac
     1621 cgtataggag attatagggt catctgtgat atacaagatg ataaacttgt tatcctagct
     1681 gttcacatag cccatagaaa gcaagtttac aaactcaaat tgccaaacaa taaacgatag
     1741 aggtttaaag taatgtattt tgacgaattt aaagagtatg tagaaaacaa tagccgtgct
     1801 catgattatt tctttgaaag ggcacttgat tatcaaaatg ctaaaaatgc taggcgaaca
     1861 cccgctcata ggcgatggaa agagcaaaag gtactcaaag aagttgagac tatgtggacc
     1921 aatgttgtca agcaacttta tgacaacatc aagttaaacg ggaagttcag gaaacggttc
     1981 atgcaccaag aagaaattga tgagtgggtt tccttcatga acgaacatga aattttggaa
     2041 tcattcgcag atagcatggc tgaaatagag tttgagtagg aacgtcgcta acggagcgtt
     2101 gatcaaagaa gaattagagt ttttaattag ttaaggagat aagcatggaa actgaaaaaa
     2161 taaataatgt aaatatttta cgaagtaata actcaagact ttcgggatac gcaacaagtg
     2221 cgagttatcc ccttatattg cccattatag ttgagtttga attgtataat attaagcaaa
     2281 gcaaaaccta tctatttcaa ataacagcaa ctaaaataaa cgatagaaga caaaataatc
     2341 atatcaaaga cttactatca ctatccagca atcagactac tgtcaccatc tccgcagaga
     2401 gacataatac attttttccg tatgaaggat acggaacagt ggcaacaaaa cttgatttct
     2461 cgtttaacat agacagtccg ggtgactatt gcattgcgct tacacttttg gatagcgagg
     2521 gatctttatt agataagcac tcaaattatt acatttttgg agaagagtaa ttatgagtga
     2581 atatcttaca ctatataaac ccgaaacctc caacattgat gccaaaaata atggtataat
     2641 agacttagaa aagagtcagg aggaatctat tatgtcacaa gaaatttata gcaaatcaga
     2701 aatagatttg aagtttgaaa atcttgaaac gaaaattgat agcaaattcg atttattgat
     2761 gcagaaaatg gatgatggtt ttgaaaaaca acgattaaat acagaaaaaa tgttgtcaga
     2821 tttcaagcta aatctagtga ctgatcaaca gaaaaataaa aaagaattta tgtattgggc
     2881 tatcggtatt attattgcct tagcaggtat tgcttttccg atttggttcg ggaaataaaa
     2941 aaagccccac gctctcaaag tttggcgact ctgagcgtga ggcgaaaccg tataagaaac
     3001 aaccattaaa aaggtcgttt tcttgtacct aaaattatat cacacaaagg tggtgatgcc
     3061 aatatccttt caaacgacct cgtccaaaag t
//
LOCUS       DARYXZ010000097         3076 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYXZ010000097 DARYXZ010000000
VERSION     DARYXZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3076
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            18..98
                     /locus_tag="TV186_001971"
     tRNA            18..98
                     /locus_tag="TV186_001971"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="TV186_001972"
     tRNA            105..175
                     /locus_tag="TV186_001972"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="TV186_001973"
     tRNA            187..259
                     /locus_tag="TV186_001973"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="TV186_001974"
     tRNA            268..339
                     /locus_tag="TV186_001974"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            358..441
                     /locus_tag="TV186_001975"
     tRNA            358..441
                     /locus_tag="TV186_001975"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Leu,seq:caa)
     gene            complement(785..1915)
                     /locus_tag="TV186_001976"
     CDS             complement(785..1915)
                     /locus_tag="TV186_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1533322.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            2479..>3076
                     /locus_tag="TV186_001977"
     CDS             2479..>3076
                     /locus_tag="TV186_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1533323.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRG"
BASE COUNT          987 a          573 c          677 g          839 t
ORIGIN      
        1 gtaatttaat atgttttgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctgaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttcag
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttagttttat acttaaagcc
      361 ggcgtggcgg aattggcaga cgcgctggac tcaaaatcca gtgtccgcaa ggacgtgccg
      421 gttcgacccc ggccgccggt atagtttaaa aatattgaaa aaacaaggtt tgtaaacctt
      481 gtttttttgt tttatgactt gatgtcagag gatcagattg gtcctctcta gatgttaaag
      541 gtaatgagaa tcttggcttc aaagctccta aatccaaagc attgcgcttg atgtctttga
      601 tcacctgtta gtggcgtgca gcttagcgtt tgaatttgga ataaggttgc tccaaggcat
      661 gtgtgatgtg agctttggat actaggactt ttagccaatt ctttgtgggt gagctttttc
      721 tttacgtttg gttttgatta atgtcgcaat atcagttatc atgtgttctc tggttaatga
      781 cgctttagca aatatcgtat tgtcttagca tcttgtttga gaaataaagc agactaatta
      841 agataagcga acccaaggca agtgttggga tggttacggt ataaaaagca ctgaaaactt
      901 caccaagatg ctcatcagga atctcagttc gtaaaatagg tttttgggta acatgcgtta
      961 ttccgagaaa tagacaggaa agaaaccaaa gaagcaacaa accaaaacgg ttggggacta
     1021 atgctgtaag gccaataccg gtgcccaaaa gggtagttgc tagccaaaaa gcttttccta
     1081 cacttaactt ttgcaagaca aggttagcaa caaaggttgt tcctaccagg gttccgatag
     1141 cacttacaga tactaagagg ccataaaaag ctgaattccc tacctctctt gctattaata
     1201 actgatagac atttaagctg gcaaaaagga aattagcgat agcacctccc aatgtgatgg
     1261 ctaacaccac tttattgtgc cagataaagc gcaagccact taaaaagtct gttcgttcat
     1321 ttgtttgttc aattatttct ttaaatgcta ttcttctaaa aaataggatt gaacctaaga
     1381 aggtaacgat attaatgaaa agcaaaggaa tgtagctgat cacagaaagc aaaaagccac
     1441 tgatggcagt aaaaacataa tctgttccat tataagccac tgacatatac atttctgctt
     1501 tagctagatc tttagtagga atgagtttag gtacaagagc atcttgaaca gtataggtat
     1561 tcaacccaac catagaagcc agaaaaacac aactaaaaat aatggttaag ctaagacttg
     1621 cgtgtatctc tcttaaggac attcctaaaa taatacctaa gacagccaat aattgggccc
     1681 actccagaat cactagcagg ttcttcttag ggtacgaatc aatctttttt ccaaagataa
     1741 aggagaaggt gtttggaata aaaatgagaa agttcaataa tccaacatac caagtactat
     1801 tagtggtttc tagtacatac caggacagca ctagggtata aatcgagtca ccgcaattgc
     1861 taatcagtcg ccccagaaat aaccggcaaa aatcattata tttccttaat atcatattgt
     1921 atcctttgat aaagagttta aacatctttt atattatagt atcagatgat aaaaaatcac
     1981 tgaatgatag ctgtgtttga tgtttgcaac attttaaaat atctttgcaa aaatcatacc
     2041 tagacacata caatcccaca taagttttaa aagcattcaa ttgcctttta agatctttat
     2101 gagtcatgtt tgtaaagata tcctcttgca acagatctct taatctctaa ttgtatccaa
     2161 taagaagcag ctttgtcaat acggaagccg aatagtcttt ttgcctttcc ttgtcagctg
     2221 ggcaatcatg agggctttgt gctttgatct tttgcatcta taaaagggtg aatctattga
     2281 tgaggtgtta tcggtagtgg ggcctactga tgtcaataac tgacgtcaga taattacctc
     2341 tttaattaga aaaaaaaaaa acgaaactac ggagagaacc taataactgg ctatttcttg
     2401 ctataagcca gcgtgttaaa atcttctttg ggagaaaatt tagaaaaaaa taatatttct
     2461 atcactaagg agagaaagat gacaactaaa gaaaaacaaa caaaactaat gcgcaggtat
     2521 ggcattttct cggtagtcgt tgccctaaca gctctagcag gtctaggagc agctaatgaa
     2581 gttaaggcaa ctgctaaaaa atctttaaat gagttaccta atccagtaga aattattcaa
     2641 tataattcaa caagaactac tgatagagaa gctagaaagt atcttaatca attatatgag
     2701 tttttgaaac cttatttagg aagtttagaa gaagaagctc aaaaaggagg gccacaagga
     2761 cctgtgggac ctgctggtcc tagaggtgaa cgcggagaac caggacctaa aggagaccga
     2821 ggtcctgagg gccaaagagg tgagcaaggc ccagcggggc ctattggacc ccaagggcct
     2881 cgtggtgaca agggtgaaac tggagaaatt ggacctaggg gagaacaagg tccgaccggt
     2941 cctactggta agccaggaga gcgtggccct aagggtgaca gaggcgaacg cggcgaaaaa
     3001 ggcgagcaag gccagcgtgg cgaaaaaggc gagcaaggcc aacgtggcga aaaaggtgaa
     3061 caaggccaac gcggtg
//
LOCUS       DARYXZ010000098         3061 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYXZ010000098 DARYXZ010000000
VERSION     DARYXZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3061
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..496
                     /locus_tag="TV186_001978"
     CDS             <1..496
                     /locus_tag="TV186_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1533324.1"
                     /translation="GKTTLAKLILNYYPKHLYDGEIRIDGRNIAEINSESLYKKIAFV
                     QKNDFLVEGNVSDNIKLDGSLNLTDKLKDSLGFDETFLNKKLFRVQSLISEGEKQRID
                     LARFLNRRYSIYIFDEPTGNLDPARSKAILDYILSIKNAIIIVITHNQDIKTLEQFDE
                     VICL"
     gene            659..1781
                     /locus_tag="TV186_001979"
                     /pseudo
     CDS             659..1781
                     /locus_tag="TV186_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            1774..2949
                     /locus_tag="TV186_001980"
     CDS             1774..2949
                     /locus_tag="TV186_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1533325.1"
                     /translation="MNKKIIFKGDQDSKFAYFSLMFSAGTAIENTEELGFSHLIEHLL
                     LRSGGEQSLNELFDNNGAFIGGETSRDYINLMGYCKAENFKNIFEAIVSRVFNLNLTE
                     EELLREKRVVLVELTQYENGSKTEKLVSDNRLIFKNSKWSEDIIGVRENIESVDLKKL
                     YKFYTENIQNGEFQIAISGPNHLKEEIAIIENKLPVGRTPVKSNFPIFSSGVTERKKN
                     QQVSEISMYIDISKMTTSSHDVAILTILNAMLTGVKGSVLGGKLRTKNQWVYNIISFP
                     IFYNGLTILKILTRTPEIHKHQVVQVLKEDLVNREDLKNTKLFDKAKKRVINEVLMSY
                     EVKKVEFLKTLCREKLFNIPSWESVTGEIEKVSLNELNQFAKDALMQNKQFHIIINC"
BASE COUNT         1165 a          329 c          562 g         1005 t
ORIGIN      
        1 tgggaaaaca acattagcaa aactgatatt aaattattat ccaaagcatt tatatgatgg
       61 ggaaataaga attgatggaa gaaatattgc tgaaattaac tcagaaagtt tgtataagaa
      121 gattgcgttt gttcaaaaaa atgattttct tgtggaaggt aatgtttcag acaatattaa
      181 attagatggg agtttgaatc taacagacaa gctcaaagat agtttaggat ttgatgaaac
      241 atttttaaac aaaaaattat ttagagttca gtctttaatc tcagaaggag aaaaacaaag
      301 aattgattta gcaagatttt taaaccgtag atattctatt tatatttttg atgaaccaac
      361 tggtaatctt gatccagcta gatctaaagc catattggat tatattttat caataaagaa
      421 tgcaatcatc attgtgatta ctcacaacca agatataaaa acgttagaac aattcgatga
      481 agtcatttgt ttgtaaatga aagggggtga tgaacatgat tatggaagat tttgaagttt
      541 tagaactaga gtttgtcgaa gttcgaaatg aacaaaccac aaattggtat tttgtttaat
      601 cacaaaggca tgcaatgaga atttgcatgc ctttgtaaaa tatagaaagg acaataaaat
      661 gaataatttt tttccaaaat ggaatcagga taggattgta tattcatggc aaaatgataa
      721 attaaggata ggagctgatg ataatgatgt tctagaaatc aaaggaaact caattttttg
      781 gtcagatttt atttcttgtt gtgacgggaa taatagtatc aaagacattc aaaaactatt
      841 gaatataaaa tataatattt cagaagaaat aattacagag tatttagata aattctcaaa
      901 tcgaaattta ttggaaatat tggataatcc aataaatcaa ttacaggatt ataaatcaat
      961 tgagtcgtta gaaacatatt atgctagtga aggaattggt gggattaaac tattaaaaat
     1021 gttagggaat ctaaagattt ctattctggg atgtggtggt ggtggatctc atattgcatt
     1081 acaattagct caattaggag tgggaagaat tcatttggtg gattacgata ttgttgaaga
     1141 aaacaatatc aacagacaat ccatgttcac atttaacgat gtcggaaatt acaaagttga
     1201 ttgtgtagcc aaaaatattc agcaaagaaa ttctaaatgt ttggttacca aaagcacttc
     1261 taaaatgatt aatgtacctg atgtaaaaaa aagaaatatc tgaaagcgat tgggtattct
     1321 gttgcatgga tgaacctcct tatatagcac agaggattgt aaatagagca tgttatttat
     1381 taaaaattcc aagtatatac tgttttagcc aacgtagtgc ggggaaactt ttgttttgta
     1441 atcctaatat tgaagattct ggctgtattg attgtttgtt atctgaacaa gataatgaaa
     1501 actttcaaaa gctggtgaca acgttcacta cctataatag gaaattggta actgcaaata
     1561 tcttaccaaa tattttatta ttgacatcgt gggtggttaa acgatggtta gattgtgtaa
     1621 cagataaaaa tagtaatgta tggaatatgt tgttgagatt tgatttttat aaatatatgg
     1681 aagaaaaatt tcaatatttt tcgaaacaag atagttgtcc aacatgtgct aagggtctta
     1741 gtacaagtaa attatgggag attttaaaaa tagatgaata aaaaaattat ttttaaaggt
     1801 gatcaagata gtaaatttgc ttatttttca ttgatgtttt ctgcaggtac tgccattgaa
     1861 aatacagaag aacttggttt ttcacatttg atagagcatt tattattacg atcaggcgga
     1921 gaacaatcat taaatgaact atttgataat aatggtgcat ttattggagg tgaaacttct
     1981 agagattata ttaatttgat gggttactgt aaggctgaaa atttcaaaaa tatatttgaa
     2041 gcaatagtaa gtagggtatt taatttaaat cttactgaag aagaactgct aagagaaaaa
     2101 agggtagttt tagttgaact aacacagtac gagaatggga gcaaaacaga aaaattagtt
     2161 tcggataacc gcctaatttt taaaaatagt aagtggtcag aagatattat tggtgttagg
     2221 gagaatattg aatctgttga tttgaaaaag ctttataagt tttacactga gaatatccaa
     2281 aacggagaat ttcaaattgc tatttcagga ccgaatcact taaaagaaga aatagcgatt
     2341 attgaaaata aattaccagt tggaagaact cctgttaaat ctaattttcc tattttttct
     2401 agtggtgtaa cagaacgaaa gaaaaatcaa caggtttctg aaatttcaat gtatattgat
     2461 atttcaaaaa tgacaacatc atctcatgat gtagcgatat taacaatttt aaatgcgatg
     2521 ttaacaggag ttaagggttc agtgttagga ggtaaattaa ggacgaaaaa ccaatgggta
     2581 tataatataa tttcattccc aatcttttac aatgggctca ctatcctaaa gatactgact
     2641 agaacgcctg aaattcataa gcatcaagta gtacaagttc taaaagaaga cttagtaaat
     2701 agagaagact taaaaaatac gaaattattt gataaagcta aaaaaagagt tatcaatgaa
     2761 gttcttatga gctatgaagt gaagaaagtc gagtttttaa agacactttg cagggagaaa
     2821 ttatttaata tacctagttg ggagagtgtt actggggaaa ttgagaaagt ttctctcaat
     2881 gaacttaatc aatttgctaa agatgctctc atgcaaaaca agcaatttca tatcataata
     2941 aattgctaat atatttgtta aagtgttctt gataattttg ataaattgtt ttatttaaag
     3001 aattgaagat ttttaaggct tcttctatct tagagtttga tttttctgtg tgaatattaa
     3061 a
//
LOCUS       DARYXZ010000099         2736 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYXZ010000099 DARYXZ010000000
VERSION     DARYXZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2736
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(106..612)
                     /locus_tag="TV186_001981"
     CDS             complement(106..612)
                     /locus_tag="TV186_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533326.1"
                     /translation="MKRKILLLMMLLVGVFIFSKRYELYYFFQGKEYLRPNESIELAV
                     RPKYEQIEYSSDLYLESDEKVLLKLEGRDIWSEYIYRRTDSYLSKIGYRYSITEQVIE
                     KYDSTKDNGVVIVEAGHKGATIDGDGLIVPLKGKRKYSVTEDHDYSITITNLSDQPVA
                     FRAIVADR"
     gene            complement(609..2015)
                     /locus_tag="TV186_001982"
                     /pseudo
     CDS             complement(609..2015)
                     /locus_tag="TV186_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2006..2365)
                     /locus_tag="TV186_001983"
                     /pseudo
     CDS             complement(2006..2365)
                     /locus_tag="TV186_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2377..2643)
                     /locus_tag="TV186_001984"
     CDS             complement(2377..2643)
                     /locus_tag="TV186_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1533327.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
BASE COUNT          709 a          645 c          514 g          868 t
ORIGIN      
        1 gtgacccaac aaaccatcac tagaagctat aaggggagct tttctatgcc taacaaaaat
       61 ctaaaatcaa taacagaaaa acctaaagca gttcatgcgc acatactacc tatctgctac
      121 tattgctcta aaagcaaccg gctgatcgga caggttggta atggtgatac tatagtcatg
      181 atcttctgtc acactatatt ttctcttccc cttcaaggga acgatgaggc catctccatc
      241 aatagtagct cccttgtgtc cagcttctac aataactaca ccattatcct tagtggaatc
      301 gtatttttca ataacctgtt ctgttataga ataccgatat cctatcttac taagatagct
      361 gtctgtccgt ctataaatat attcagacca tatatcacga ccttctagct tcagtagcac
      421 tttttcgtcg ctttctaggt ataggtcaga ggaatattct atttgttcat actttggtct
      481 caccgcaagc tctatactct catttggcct tagatattct tttccttgaa aaaaatagta
      541 aagctcatag cgtttggaga agatgaaaac acctaccagc aacatcatta ataacaggat
      601 ttttcgcttc attttgactt cttccttttc atataaccat ctatacctgc ttggatcatt
      661 tgagtatcac cctcattgtc tccatagtga cctgatgata agttctttaa ccactttggt
      721 atatccttat cagaaaagac ctgggcaatc tcagccgccg tttttaaata agtccctgaa
      781 gcatctaaaa agcctgtacc aacataacca tagaggtagt tgccagcata gtcgcctggc
      841 aattctgatt cccactgtct tgaccagaca gaatagttat ggccatgata ggtccttgac
      901 ttcaaatcca agggctgacc cgtattgaca aggtcataaa attgtttgtt gtcaagtatt
      961 gcagcactta attgacttcc agctacctgt gaaaggtagg gagcattgac attcactgat
     1021 aggatatcat ctcccatctt gttgacaatc aaacgaaaat taatacccga cgattgtaat
     1081 tttttcccta ggtcttcctc aatttccttt gcatatttat tatttttaag gtctcactct
     1141 ccatcataat tgcttctcgc cttccaatag tcatcaaagg ctgttttatt gagaaaatag
     1201 aggtaatcct cataggcagc tacaagtcgc tctgattttt gtagtggcct ttcagagctg
     1261 cttttgatgg ttttaatggt ctgagtcagt atgttgtgat aatggttttg agtgtacttt
     1321 gaggcattga cagggctaat cttttgattc ttcaggctag tcacccagct catatctagg
     1381 ccagcagtcg agtagctgcc gtcgctgctc atgaagacct gactgagctg tgttgcgccc
     1441 tgaatggcta accgcaaaat aactaagctg tccctaaagc agtctgaggt ttgagttaga
     1501 aaccattcaa ggctttccaa tttggtcgta acatctcgaa tccctatttc cagctggttt
     1561 ttggcatggt atagtgtaga ggtatcagac caaagggtgc catagtctcc ggttaaaaga
     1621 ctactgacct gcttcataaa cgattcgttt tcatcaatct gtgcttggat cacttgcact
     1681 tgccgttctc ttagcctctt cagctcggtt aagtgatcac gatccagggt tccgtatctg
     1741 gcaatctgag catctgccct ttgataggtg gtcaactcca cttggatagc atcaatcgct
     1801 gcttgtagct ttttgataga gggaatgatg atcgctgtaa aaagtcccct acctgctgta
     1861 taggctgctc cctgtagctc tcccgaatcc agactagcaa tgagatggtc gcaaccactt
     1921 gataacctgt ccgttatttc attggctatt tggatattgt ttgtcatggc ttgaatcaag
     1981 gcctttgact ctgctgcact gtaggtcact cccatcgtaa acggctcctt tcaccgataa
     2041 gctcttcttt gtccctctct agtctacgac gaacccccat cgtatagatt gacacgtgat
     2101 ccagatgctc atcaacatag cgatccattt gtctgatcaa gtggtcattg gcctcttgct
     2161 ctgcgtactt tccagcttag tcctcaggca tatggttcaa tagggactca agggcaaaag
     2221 agaggtgctg acagtctgct tgaatctccg agactgcttg ttcatgccgt cgtttcatcg
     2281 acaaaagatc ctcctctagc cactccagct cattgatctg tcgggttagg gcaagaaatt
     2341 tttcttcaga ttcttctttg atcatgactt attcccctat cttgttgctt cctctaggtc
     2401 tcttttctct aatttggccg caagctgagg aaatttatta gcctgaataa ggactgcctg
     2461 actaaagtcg ctgacagcct gcagcagttg attagagacc tgacgtccct tttccatacc
     2521 tgcaataccc ttggtcacac taaatgcaac ggactgttgg tgaaccctac tggtgtctac
     2581 acctaccaat tcactaatag cagcagaagc agccacaggg cttgatgtaa tggtatcact
     2641 catacaattt ctcctttata acccttatgt cttttattat atcacaggat aatagccatt
     2701 gtgcttatag ctcttaccta aataatagca actgat
//
LOCUS       DARYXZ010000100         2496 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYXZ010000100 DARYXZ010000000
VERSION     DARYXZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2496
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(171..461)
                     /locus_tag="TV186_001985"
     CDS             complement(171..461)
                     /locus_tag="TV186_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533328.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TV186_001986"
     CDS             complement(442..834)
                     /locus_tag="TV186_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533329.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TV186_001987"
     CDS             complement(816..2105)
                     /locus_tag="TV186_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533330.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..>2496)
                     /locus_tag="TV186_001988"
     CDS             complement(2107..>2496)
                     /locus_tag="TV186_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533331.1"
                     /translation="IGGLLMVFSLNGKRTEEQQKKDLETSIAKLLVHDYEDVKEVKFT
                     GWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPDTFKLVEKNSLEEMG
                     PVKYRIKDIEKVSLEGVSITYSREKRS"
BASE COUNT          645 a          610 c          461 g          780 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tcctat
//
LOCUS       DARYXZ010000101         2475 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYXZ010000101 DARYXZ010000000
VERSION     DARYXZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2475
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            51..1004
                     /locus_tag="TV186_001989"
     CDS             51..1004
                     /locus_tag="TV186_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1533332.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1064..2263
                     /locus_tag="TV186_001990"
     CDS             1064..2263
                     /locus_tag="TV186_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1533333.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          748 t
ORIGIN      
        1 tggctagtgg tattcttttc atttcagcct tattttgata tgatagacgt atgaattttg
       61 aaaagattga acaagcctat gagcttatat tagaaaatag ccagctgatt gaaaatgatt
      121 taaaaacgca tatctatgat gctattgttg agcagaattc tttttatctg ggagcccaag
      181 gagcaagccc tcaggttgct aaaaatattg agacgttgaa ggccttgcag ttaaccaagg
      241 aggagtggcg ccaggcttat cagtttgttt tgatcaaggc tgggaaaaca gagccattac
      301 aggccaacca ccaatttacc ccagacgcga tcggctttat catgctttat attttggaga
      361 ccttgagctc acaagagtca cttgatgtgc ttgagattgg cagtggaaca ggtaatttag
      421 ctcaaactat tttaaaccac tcacataaga gcattgatta tttaggcatt gagcttgatg
      481 atttactaat tgatctatca gctagtatcg ctgaaatcat ggggtcatca gcccagttta
      541 ttcaagagga tgctatcaga cctcagctgt taaaagaaag tgatctcatc attagcgatt
      601 tgccagttgg tttttatcct aacgacgata ttgctagcag gtatcaggtg gctagctcag
      661 atgagcatac ctatgcccat catttactga tggagcaagc cttaaagtac ctgaaaaaag
      721 atggctttgc tattttctta gcaccggtaa atcttttgag cagcccacaa agtcacctct
      781 taaaacaatg gctgaagggc tatgctcagg ttgtggcctt gattactttg cctgaggctg
      841 tgtttggaaa tccagctaat gcaaaatcga ttattgttct ttgtaagcaa tcgaatcgct
      901 ttgcagaaac ctttgtttac cccattaggg atttgaaatc tgttgataat gttcgtgatt
      961 ttatggaaaa cttcaaaaat tggaaacggg ataatgttat ttaagagaat tttttgatat
     1021 aatagaaaag cattgcagaa aacgatttca agagaggtaa aacatgtcaa agacaattgc
     1081 aattaatgca ggaagctcca gcttaaaatg gcagctatat caaatgccag aggaaaaggt
     1141 attagcacag ggaattatcg aacgtatcgg tctgacagac tcaatctcta ctgttaaata
     1201 cgatggcaaa aaagaagagc atattcttga tattccagat catacagagg ctgttaagcg
     1261 cttgttgaat gatttgattc attttggcat tattggtacg tatgacgaga tcacaggtgt
     1321 tgggcaccgt attgttgcag gtggtgaata cttcaaggaa tctgtggttg ttgatgataa
     1381 ggttgttgag caggttgagg agttagcagc cttggcaccc ttgcacaatc cgggggcagc
     1441 agcaggtatt cgtgcctttc gtaagatttt gccggacatt acgagtgttt gtgtgtttga
     1501 tacttcgttt cataccacaa tgcaaaagca tacctacctt tatccaattc ctcaaaaata
     1561 ttatacagat tataaggttc gcaagtacgg ggcgcatggg actagccata aatatgttgc
     1621 tgaggaagca gcaaaaatgc tgggtcgccc tctagacgaa ttaaagctca ttacagccca
     1681 tgttggtaat ggtgtgtcta tcacagccaa ttatcatggt cagtcagtgg atacctctat
     1741 gggctttaca ccgcttgctg gtccgatgat ggggacacgc tctggtgata ttgatcctgc
     1801 tattattcct tatttgattg ctcaggatcc tgagctaaag gacgcagcag atgtggtcaa
     1861 tatgcttaac aagcaatctg gattaggtgg tgtgtctggt atttccagtg atatgcgtga
     1921 tattgaggct ggcttgcagg ctaacaatcc agatgccgtc ttagcttaca atatctttat
     1981 cgatcgtatc aagaaattta tcggacaata ctttgcggta ttaaatggtg cagatgcctt
     2041 ggtctttacc gcaggtatgg gtgagaatgc tcccttgatg cgccaagatg tcgtcaatgg
     2101 cttgtcatgg tttggtatgg aaattgatcc agagaaaaat gtgtttggtt atcgtggtga
     2161 tatttcaaca gcagcttcaa aggtgaaggt gcttgtcatc tcaactgatg aagagctgtg
     2221 tattgcgcgt gacgttgaac gcttgaaaca gactatatca taatctgata atatactctt
     2281 agctcagctg atcagtttta aagagtccaa aaaatacttt taattggtac cgacctccaa
     2341 aagttagact taaaggttta acgattggag gtcggtatta ttatatagcc aaatattctc
     2401 aagacaaaga cagccaaaaa atgagacggt cgtaaccgtc tcaaaaaagt ttaatttaat
     2461 taaaaacatt cattt
//
LOCUS       DARYXZ010000102         2424 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYXZ010000102 DARYXZ010000000
VERSION     DARYXZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2424
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..925)
                     /locus_tag="TV186_001991"
     CDS             complement(<1..925)
                     /locus_tag="TV186_001991"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533334.1"
                     /translation="MSVQVALKKALKPTWKRKLRQSWSIQRSTHLFSWYMVKHMDLTS
                     FRYVETNDYVLPEYGFKIHISGTFQNYKAIFSVVFPYLKCHHISFKYLKDEKMILENV
                     SDMEDPSESGKFITIYPRDREHCKQLLSDLYELIPVETEGVYILSDRNYKDSNVIFYR
                     YGLIEPREKVFVNAVPILIGPNGEQWQDFQKCYFDLPHWIEDLQEKQILLSSYLSENY
                     QVESLLKQSNGGNIYKAIHLDTGKNVVIKECRSHIICTASISKKQLRDNEWNLSGLIT
                     NNIPKSIEKVHEWINDYYIYEYIDGQDLLDCC"
     gene            complement(1341..2207)
                     /locus_tag="TV186_001992"
     CDS             complement(1341..2207)
                     /locus_tag="TV186_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1533335.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          767 a          460 c          324 g          873 t
ORIGIN      
        1 tacagcaatc tagtagatct tgaccatcaa tatattcata tatatagtaa tcgtttatcc
       61 attcatgaac tttttcaata ctttttggga tattattagt tattagacca gatagattcc
      121 attcgttatc tctcaactgt tttttactaa tactagctgt acagataata tgagagcgac
      181 attctttgat aactacattt tttccagtat ctagatgaat agctttataa atatttccac
      241 cattagattg ctttagtaag ctttccactt gataattttc acttaaatat gacgacaata
      301 aaatctgttt ttcttgtaaa tcttcaatcc aatgaggtaa atcaaaataa cacttctgga
      361 aatcctgcca ttgctctccg tttggtccaa ttaatattgg aactgcattt acaaaaactt
      421 tttctctagg ttcaataagt ccatacctat aaaaaataac atttgaatct ttatagtttc
      481 tatcactaag tatatagact ccttctgtct caacaggtat caattcatac aagtcactta
      541 ataattgttt acagtgttct ctatctctgg gataaattgt gatgaatttc ccagattccg
      601 aaggatcttc catatcggat acattttcta aaatcatttt ttcgtctttt aaatatttaa
      661 aagaaatatg atgacatttt aaatacggaa atactacaga aaaaattgct ttatagtttt
      721 gaaatgttcc tgaaatatga attttaaatc catattcagg taaaacataa tcattcgtct
      781 ctacatatct aaagcttgtc agatccatat gcttcaccat gtaccagctg aataaatggg
      841 tacttctctg gatgctccat gattgtctta actttctttt ccacgtaggc ttcaaagctt
      901 ttttcaaagc tacttgaaca ctcacgagaa tcttctttat agatacattt ttaagtaatc
      961 attggttttc tcatagcaat acatctcctc agtcttatta gtataaaact aaaaacgctc
     1021 acattaacag gtctttttga gcgtttttag taggactagt tactaaatta tggtttgtag
     1081 attggacatt tccaagtcac aacaaagcct ttcactggcg caaagcatct actagcctcg
     1141 tatgcaaatt gagtcatgtt tgtgatctcc tttcattctt gatgagtcta gtgtatcatc
     1201 aaaaaccgta ccaaagctaa actgttcata tgttcaaatc atggttttga cattaatcaa
     1261 aaaacagtag ctcaaaaagc cactgtttgc tactagctaa gcatctaaac cattttgctt
     1321 atcaatgctt taagttgcat ttattcaact tcctttaacc atttctctaa actatctgaa
     1381 taataggctg cactttcatc acaatttaat gcctttaaga tgtgtatggc gtcatttatt
     1441 tgctttaagc ctagttcctt ttccccttta caatataggt gctgaccatc agcaatcata
     1501 taaacaattc ttaagtaggt gtcattttct tcaaaaaaat gattgttaat cattttatca
     1561 aaatatgcag ctatacctag ccttttttcc tgagtagctt taaacagccc atttaataaa
     1621 atgctgtgca ctaaatttcg atgctgccaa agctcctcaa aaaagtctac tcttcctagc
     1681 atttctcgag tataccgcaa atacacatcc aaggataata agggagaaat atctgaaaat
     1741 aattgtaatt cgtatattcc ccaaatctcc actgaaaaca aataatcata taaaaagctt
     1801 tgctcatctg gagtcatttt gatattctcg tctaaaaaga gcatttggct tttaatcatc
     1861 aaagcattta aaaaatagat atcctttttg tataaatgat actgctccag ctcttttgta
     1921 tacaattgat gtaagctgga caggtctttt tttgatatgg cctcccagat ctcttgcttt
     1981 aggacagcat atggggaagg cttaaagcca tttgctagat agataaattc attgagctct
     2041 gtccgaatat tgctaagtcc aaccaatagc tttgagattg ttatatcgga ttcaccattt
     2101 tcaaatctgc ttaacatcga gtgagaaaag tcatctcccg tcgcttcctt taacgatatg
     2161 tgtcgcgatg tccgcagtaa tttaaacatt tctcccatat attgcatatc aatacctctt
     2221 caatctttca ttttagtata gtatataacc ttaaaaatgt aaatccagtc ttgattgcat
     2281 aaacctttaa ttcaacgttt gatgctacta aatatcctat ttttctgaag tagatcctca
     2341 tctttatgct ataagcactt gctgcgtttt agaaaatggg ctaaatcagc tatactcctt
     2401 tttaataaca aaaaagcctt attt
//
LOCUS       DARYXZ010000103         2345 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYXZ010000103 DARYXZ010000000
VERSION     DARYXZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2345
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..105
                     /locus_tag="TV186_001993"
     CDS             <1..105
                     /locus_tag="TV186_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1533336.1"
                     /translation="FLEYLAEAEDEFTAAEIVLIDSILEQYEANKKGE"
     gene            108..722
                     /locus_tag="TV186_001994"
     CDS             108..722
                     /locus_tag="TV186_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1533337.1"
                     /translation="MARNWKIVGKYPQPNALGVIEGTHVIITGDDGASIPQTIKKDLS
                     STNDLDVIKMVLDEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTATTAQTAAGLARA
                     AAERTQKMINLQTIHVLTSGGKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKHED
                     LAGEGKLVFVYVNEAFEYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            735..1025
                     /locus_tag="TV186_001995"
     CDS             735..1025
                     /locus_tag="TV186_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533338.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            1028..1207
                     /locus_tag="TV186_001996"
     CDS             1028..1207
                     /locus_tag="TV186_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533339.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
     gene            1319..>2345
                     /locus_tag="TV186_001997"
     CDS             1319..>2345
                     /locus_tag="TV186_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1533340.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGETDYKKACHAIKAAGYATASDYAELLIQLIEQNDLQKWDAEALAKRKESQMISS
                     QCREVIEFYINLANAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASA
                     QGWEVHRMPTDANPRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNAD
                     ALYVGGPARFNTRDFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETSKSGTFTLDA
                     AEINVRRW"
BASE COUNT          709 a          453 c          584 g          599 t
ORIGIN      
        1 tttttggagt atttggccga ggccgaagat gagtttacgg cggccgaaat tgtactgatt
       61 gacagcattt tggaacaata cgaagcaaat aaaaaaggag aataattatg gctagaaatt
      121 ggaaaatcgt cggcaaatat ccacaaccaa acgcgctagg ggttattgag ggtacacatg
      181 tcatcatcac aggtgatgac ggtgcatcta tcccgcaaac gataaaaaaa gatctgtcat
      241 ctacaaatga cctcgacgtt attaaaatgg tcctcgacga atttaaaaaa tcagagtatg
      301 tcgaaatcgc aatgggcgag gcagtccaaa aagtggacga cttggaaaaa ctatcgcaag
      361 aaactgctaa gacagcaaca actgcacaaa cagccgctgg tttggccagg gcagctgcag
      421 agcgcacaca aaagatgatt aacttgcaaa ctatccacgt tttgacaagt ggtggcaaga
      481 ttgagcctga tatctataaa ggcatgcttg agcttattga gccagctaaa aaaggtcagt
      541 atcaagagca tgatgtcttt actgtgctag atgacaagca tgaggacttg gccggcgagg
      601 gtaaacttgt ctttgtctat gttaacgagg cctttgagta cgacaagcaa accctcaaag
      661 atctggaatc agaggataaa gtcacagtta tcaagtacgc tgatttggtt aaaggcaaat
      721 agtgaggtga ttagatgata gattttgtgc aaataggcac tttttgtggc gctgctctgt
      781 ctatctttgg tgtttgggga tttatcgtca atccttttaa aaaagcgctg gaggctaacg
      841 agctagccat ggcccaactc aaagactcga tcaaggagct agcctacgag ctaaaaaatc
      901 ttgatcgtga tggagagata accaaaaaga ttatcgatcg gcatgaggag cgtttaggac
      961 gtgtagagga cgacattatt gtcaataaag agcaaatcaa aacattattt aaaaaaggag
     1021 actaaaaatg gataaatggt ttaaaaaagt agcaatcaaa acaattaaga caatggccca
     1081 aaccgctgta ggggttattg gatcaagcgc attgattact gacgtcaact ggcaggtggt
     1141 ggcctcaaca gttattatgt caggtattgt ctgcgtcttg atgaatgtgt ctgacatcaa
     1201 ggaatagcat tatgcgagca atcacacgat tagcaatagt cctagcaatc gcaatactat
     1261 atttaccgct atctgtgatt gctcttatct tttatccgtt tttaggtgag gaggacagat
     1321 gaccttttta gacgacataa aaagcgcagt tatcgcagag tggcacaatc ataagatttt
     1381 gccatctctg acggctgctc aagctatttt agagagcggt tggggcaagt atgccccaca
     1441 taacgcattg tttggtatca aggcagatag ctcatggtct ggtaaatctt ttgataccaa
     1501 gacacaagag gagtatcagc caggtgtcgt gacggatctc gtggaccgct ttagagccta
     1561 tgacagttgg gacgagtcaa tccttgatca tggccagttt ttagtggata atccacgata
     1621 caaatcagtt atcggggaga ccgactataa aaaggcttgt catgccatta aagcagctgg
     1681 ttatgccact gcaagtgatt atgcagagct gcttatccaa ctaatagagc aaaacgacct
     1741 acaaaaatgg gacgcggaag ccctagcaaa aagaaaggag tcacaaatga ttagttcgca
     1801 gtgtcgagag gttatcgagt tttacatcaa tttggctaat gctggtatgg gtgttgataa
     1861 ggacggggct tatggcacgc aatgtgcaga tgtcccttgt tacgcagcta agcactggtt
     1921 tggtgtcgat ctctggggca acgcagcgga cttactagat agcgcaagtg cgcagggctg
     1981 ggaagtccat cgcatgccta cagatgcaaa tccacgagct ggggcatttt ttgtcatgga
     2041 cgcttggttt ggtggtatca attatggtca tacgggtctt gtgtacgttg actcagatgg
     2101 ttacactatg cagactatcg agcaaaatat tgatggtaat gcagatgcgt tgtatgtagg
     2161 gggtccggcc cgttttaata ctcgtgactt tactaatgtg gccggctggt tttatcctcc
     2221 ttatcaggga gatgttgctg cacaaacggt cagcacagac ccgcaaacct cagacacgat
     2281 cgtagagaca tcaaaatcag gtacttttac acttgacgcc gcagagatca acgtccgccg
     2341 ctggc
//
LOCUS       DARYXZ010000104         2293 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYXZ010000104 DARYXZ010000000
VERSION     DARYXZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..403
                     /locus_tag="TV186_001998"
     CDS             <1..403
                     /locus_tag="TV186_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HEL1533341.1"
                     /translation="HYNKLIEKFSCLGVQFLTSPFCHPWSLAIKHGIEYHSPLYCPAQ
                     KTEFEIDMYGDVYPCPFLHDKIHLMGNLISDDFETIWYSGVEQLNRRAWSSNDSCKNC
                     KLFNDCGGGCYAMAFVSQLEYDKRCILHANQ"
     gene            390..650
                     /locus_tag="TV186_001999"
     CDS             390..650
                     /locus_tag="TV186_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1533342.1"
                     /translation="MQISKNWFIRFEPNFQTTQNTILFNKVSGELFEVTEVYYDCINS
                     LRIGVDFQALLMEKYAVNAGDVIDVEDTILKNLISLGVILNE"
     gene            643..1542
                     /locus_tag="TV186_002000"
     CDS             643..1542
                     /locus_tag="TV186_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002900052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533343.1"
                     /translation="MSDITIRHVKKSFHHQVVLDVPSFDVKRGEIVAIVGANGAGKST
                     LIKMISGLMLQDTGSVLVYHHKNTSAAIHRDVKFVLESGRGYYEYLTANQNIDYFLHL
                     NNLSRSQVKEELAELCQKLAFNPYTDRLVSELSQGTRQKLSLIIALLCQPKVLCLDEP
                     TNGLDVVAKKQFATLLLELSQKKQTIILMTTHDIFFVKELSARICVMSKGKIKKQGSF
                     SEIFGENNTWMKYRIGIPKFEKAIFDQLFPFLAYQVEDERLVVEVTDSQTKHHIFEHF
                     EIIFFEEVEKSIEELLYEVITDD"
     gene            1532..2272
                     /locus_tag="TV186_002001"
     CDS             1532..2272
                     /locus_tag="TV186_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533344.1"
                     /translation="MMIKEIQRELKRQLQEMMQFKFNLFFANFGILIMVSSYLHYFED
                     TQSQFLLLCLLFTWYFTSHSLTHPIFFIEDDLYDRTLISVIQSSKSVFHVLMLKIIVQ
                     LLVDLVKAIPIVIMLSLLNNIDFPESSLRVMGSFVACFLTVISTYGLGFCLSSLCFVF
                     NRTSSVTALISYFMLYFTGILTPLDGSLGLIGKMFPYYALRNAIMSPSYQSVCWIVAY
                     GMIYWSVGTLLFSRALTMAKKRGSLFHV"
BASE COUNT          703 a          333 c          461 g          796 t
ORIGIN      
        1 acattataat aaattgatag agaaatttag ttgtttaggt gttcaatttt taacatcacc
       61 tttttgtcac ccatggtctc ttgcaataaa gcatggaatt gaatatcatt ccccacttta
      121 ctgtccagct caaaaaacgg aatttgagat tgatatgtat ggagatgtct atccttgtcc
      181 attcttacac gataaaattc acttaatggg aaatttaatt tctgatgatt ttgaaactat
      241 ttggtactct ggagtagaac agttaaatag aagggcttgg tcaagtaatg atagttgtaa
      301 aaattgtaaa ttatttaatg attgcggtgg agggtgctat gccatggcat ttgtttcaca
      361 gctagaatat gataagaggt gtatattaca tgcaaatcag taaaaattgg tttattagat
      421 ttgaacctaa ttttcaaacg acacaaaata cgatattatt taataaagta agcggagagc
      481 tgtttgaggt aacagaagtt tactatgatt gtatcaattc tctgagaatt ggtgtcgatt
      541 ttcaagctct tctgatggaa aagtatgctg tcaacgcagg ggacgtgatt gacgtagaag
      601 atacgatttt aaaaaatcta atatcgctag gagtaattct taatgagtga catcactata
      661 cgccatgtca agaaaagctt tcatcatcag gtagtcttag atgtgcctag ttttgatgta
      721 aagcgtggag aaattgttgc tatcgttggt gcaaatggtg caggtaaatc aactttgatc
      781 aaaatgatct ctggtttaat gctgcaagac acaggatctg ttttggttta tcatcataaa
      841 aatacttcag cagctattca tcgtgatgtg aaatttgtct tagaaagtgg taggggctat
      901 tacgagtatc tgactgcaaa tcaaaatatt gattactttt tacatttgaa taacctgtca
      961 cgtagccaag tcaaagaaga attggcagag ttgtgccaaa aattggcttt taatccctat
     1021 actgatcggt tggtttctga attatcccaa ggcacaagac aaaaattgtc tttgattatt
     1081 gctcttcttt gtcagcccaa ggttctgtgc ttagatgagc caacaaatgg tctagatgtg
     1141 gttgcaaaaa agcaatttgc aaccttgttg cttgagctta gtcaaaaaaa gcaaacgatt
     1201 atcctgatga cgactcatga tatctttttt gtaaaagagc tatcagcaag aatttgtgtc
     1261 atgagtaaag ggaagatcaa aaaacagggg agtttttcag aaattttcgg agaaaacaat
     1321 acgtggatga aatatagaat cggtatccct aagtttgaga aggctatttt tgatcagtta
     1381 tttcctttct tagcttatca ggtagaagat gagagattag tcgtcgaagt gacagatagt
     1441 cagacaaaac atcatatctt tgagcatttt gagattatat tttttgaaga agttgaaaaa
     1501 agcatcgaag agctattata tgaggttatt actgatgatt aaagaaatac aaagggagtt
     1561 gaaaagacaa ttgcaggaga tgatgcaatt caaattcaat ttattttttg caaactttgg
     1621 tattttgatc atggtgtcat cttatcttca ctattttgaa gatacgcaga gtcagttctt
     1681 gttattatgt ctattattca cttggtattt tacgagtcat agcctcacac atccaatctt
     1741 ttttattgaa gatgaccttt atgatagaac gttgatcagt gttattcaaa gcagcaagag
     1801 tgtttttcat gtcctcatgc ttaaaattat tgttcaacta ttggtggatt tagttaaggc
     1861 aatacctatt gttattatgt tatcactcct taataatatt gactttccag aaagtagctt
     1921 gagggtgatg ggaagctttg ttgcctgttt tttgacagtc attagtacat acggtcttgg
     1981 cttttgctta tccagtctct gttttgtgtt taatcgtacc tccagtgtta ctgcgttaat
     2041 ttcttatttc atgctatact ttaccggcat actaacgcca ttagatggct cacttggtct
     2101 tattggaaaa atgttccctt attatgcttt gagaaatgct attatgtctc cttcatatca
     2161 gagcgtatgt tggattgtgg cttacggtat gatatattgg tcggtcggta cgttattgtt
     2221 ttctagggca ttgacaatgg ctaaaaaaag agggagtctt tttcatgttt agtgaaatga
     2281 aacgatatat gac
//
LOCUS       DARYXZ010000105         2216 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYXZ010000105 DARYXZ010000000
VERSION     DARYXZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TV186_002002"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TV186_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL1533345.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TV186_002003"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TV186_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL1533346.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          557 c          389 g          644 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagc caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagct
//
LOCUS       DARYXZ010000106         2198 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYXZ010000106 DARYXZ010000000
VERSION     DARYXZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2198
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(159..1208)
                     /locus_tag="TV186_002004"
     CDS             complement(159..1208)
                     /locus_tag="TV186_002004"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1533347.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
     gene            complement(1732..2088)
                     /locus_tag="TV186_002005"
     CDS             complement(1732..2088)
                     /locus_tag="TV186_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533348.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
BASE COUNT          650 a          394 c          438 g          716 t
ORIGIN      
        1 cttatcttag aaaagaacaa caggcacatt aatgtttaac aaaacaagag cttaaagagt
       61 tcatgacaag ctttaaccaa tgacagtgag ctaatagggc tattgttaga cgaaaaaaca
      121 gaccaataag cacttggtct gttcctaatg atgactggtt agctcagttt ctgccatatg
      181 tccttgccac tggaaagcgt aaataagcct aatacttgag cgccaatgtt ttctccttct
      241 attttcttgg cagaaatggc gacatgtcta tgagcattaa tgccgacaaa atattttttc
      301 ataccaatag acgcattagc atctgagtct gtgacataga tggcctcaag gtttccttca
      361 gcattaaaat cagctcccca caagttaatc acatggctaa tgctaacatt ggcgtaggta
      421 tgtgataaag caagggctct tccttcagtc agttcttgct tgataatggt gctgatgtca
      481 tttagtcctt tattttttaa atcatgacga gctgtcaaga gcgttgtctg atctcctctg
      541 gtgaaaacag catcgaaaat accacctcgt ttgtccttgt cctgataagg tcgattgaca
      601 tcagtagact gtgttttaaa cacatttaag tagtaaccat tgataaacat gtctagaaca
      661 agatcaggca taaccccgag ttgacgtgct gatagatttg gaaaggcttt atctctaaaa
      721 taattaaaaa gctgactatt ggtttgactg tccttggtat cgatagcagc tttcaaatca
      781 aatagctctt ggttgttaaa aatgattttt tgcttttcag ggtgtttact taaataggct
      841 tcaatctctg ttttattttg atcaaaccac caatgcagca tattacctgc cgttgctgcg
      901 ccacacaaga gattatcctt cccatcgaag gccttggtga tatcgtacca gccttgatga
      961 gcaagatatg gcgcatggat cacatcttcg ttattatatc gaaactgctc gggtgttagt
     1021 ggtgtaacac ctttggtcca tacagaagtg atctgatgtg gtacttcttt ggcataagct
     1081 tccgtagcat tcctttggta atcgtcagca taagtaatgt ttgaactcgc caggctaaaa
     1141 atagctatag cagttaagag accagctgat aaggagtgag gtttatttgg ataagctatt
     1201 gttttcatat aaccctttct tgttatggtg atattatcat taaataatgt taatgacatt
     1261 tatatattat cacaatattt tgttgagaca atgcttttga taagctttat ttattagtaa
     1321 atagtgatga gatagtagag atgctggcag actggatctc tataatggat atttcagctt
     1381 ggtttatgtt agcgttacct attttaccaa tgatgatacc gtttggtatt gttggtgtca
     1441 tgccttagac atgagctgtt attattgaga ccactaataa gagctagtgt aggctttgat
     1501 gttattggga ttcttgcaca atcttagcca agcttagtca gcaaatcagg gcattagcta
     1561 ggatagtaag gacaatggtg cagttattac ttgattagct aggcggacga tttaggagat
     1621 ggtctggtta ctaagcagat tgacaaagag aagcatagct ctatcaagtt aaaaccgctc
     1681 ggaaggttgt ctgagcagtt ttgatctatg ataacttatt gggttatttc attaaaaagg
     1741 ggaatagtcg ttataaaatt tagctaattc agatagaact gcagaaataa cttcactacg
     1801 agttttaccc ttaaagtcag ctagtagctt tttgtaatct tgatcagcca tagagtccga
     1861 ataaagagtg gcatcaaaat ggttaaggcc tagactctcc aagaatgaca ccaaatcatc
     1921 gtatccttct tgcttaggcg tcaaaagata ttccacgtca ccataaacat agtcatcagc
     1981 tttgctgatg tgggttgaag ctgttaggca gactcctgcc aaagctaggg cagccattgt
     2041 agaaaccata aatttcttac aagcttgtgt catataagtg tcctccattt ccaacggttc
     2101 ctttgtccgt cgctattttt gtgatatttt ccttatcaca atgttagttt aactcaaaat
     2161 ctgtcaaaag tcaaatgttt ttgtaattaa attaataa
//
LOCUS       DARYXZ010000107         2105 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYXZ010000107 DARYXZ010000000
VERSION     DARYXZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2105
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(109..792)
                     /locus_tag="TV186_002006"
     CDS             complement(109..792)
                     /locus_tag="TV186_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEL1533349.1"
                     /translation="MLLDVVIQFRDRRSTITIDTPSTCPHCGRTMSPQHVGESKSSDN
                     ESYSYQGHFSVIFRCSFDDCLKYFAVEYIHDQIGKGSAVAYFYRPPIRVNLPENVDKV
                     SPAFVEIYSQATIAEQEKLDQIAGVGYRKAAEFLIKDYTISKNPDDSDNIKQIMLGKV
                     ISDYLSDFPKLQALSRSVAWIGNDETHYVRRHNNKDLQDLKRFILAAAQFVAADYDAD
                     DALSFTSTD"
     gene            850..1038
                     /locus_tag="TV186_002007"
     CDS             850..1038
                     /locus_tag="TV186_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533350.1"
                     /translation="MEETASVNVTVKINNITEFSTLVEKFNEKARELEAISHELMRFK
                     FQGEIESRALSDNANEIE"
     gene            complement(1012..1479)
                     /locus_tag="TV186_002008"
     CDS             complement(1012..1479)
                     /locus_tag="TV186_002008"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533351.1"
                     /translation="MDLNQVRLLEACHRYLVDRVHIDIKENMLNDKLVFEFNGDFVTF
                     NTYQEVGHCCFYEYELGSYEELENHRSIDVTEILSILNLKSGQIGTLSMLTDITRVRA
                     YIFKLLSQADFAKFEKEIKNTNFAYNFRYVENYSYLPCVKIDKDKLFNFVSII"
     gene            1553..1741
                     /locus_tag="TV186_002009"
     CDS             1553..1741
                     /locus_tag="TV186_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1533352.1"
                     /translation="MQILLYKLRKEKRISQEEMSKVINKSSNTYRDKELGKRDFTQSE
                     MFKIANFFHKELGEIFTP"
     gene            1792..>2105
                     /locus_tag="TV186_002010"
     CDS             1792..>2105
                     /locus_tag="TV186_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HEL1533353.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKDFNSP
                     EK"
BASE COUNT          728 a          367 c          395 g          615 t
ORIGIN      
        1 tggaaggagg aacgatatga acgaactaga aagaacagcc cttaatgaaa tcatgaggac
       61 agtgacttat atagcggaga agctggataa aattgattct aagatttctc agtctgtaga
      121 agtgaacgat agtgcatcgt cagcgtcgta gtctgccgca acaaattgag cagctgctaa
      181 aataaaacgt ttgagatcct gcaagtcttt attattatgt ctacgaacat aatgagtttc
      241 atcgttacca atccacgcca ccgagcgaga tagagcttgg agtttaggga agtcggagag
      301 atagtcacta attacttttc caagcataat ttgtttgatg ttgtcgctgt cgtcaggatt
      361 ctttgatatt gtataatctt tgattaaaaa ctcagcagct ttacggtaac caacacctgc
      421 aatttgatcg agtttttctt gctctgcaat tgtagcttgg gagtatatct ctacaaatgc
      481 tggcgacact ttatcaacgt tttcaggaag attcactcta ataggtggac gatagaagta
      541 ggcgacagct gatcctttac caatctgatc gtggatatac tctacagcaa aatattttaa
      601 gcaatcatcg aaagagcaac ggaatatcac tgaaaaatgc ccctgatatg aataactttc
      661 attgtcagaa cttttgcttt cgccaacgtg ttgaggggac atagttcgac cacagtgggg
      721 gcaagtcgaa ggtgtatcaa tcgtgattgt acttctacga tctctaaatt gtataactac
      781 atcaagcaac attattattt ctctccaatc gttttattta aattatacca cagaaagggg
      841 gtggggaaga tggaagaaac agcctcagta aacgtaactg taaaaattaa taacataact
      901 gagttttcaa ctttagttga aaagttcaac gaaaaagccc gtgagttaga agcgatttct
      961 cacgagctaa tgcgtttcaa atttcaaggc gagattgaaa gtcgtgcgct atcagataat
     1021 gctaacgaaa ttgaataatt tatctttatc aattttaacg cacggtaagt aactataatt
     1081 ttcgacatat cgaaaattat aggcaaaatt agtatttttg atttcttttt caaattttgc
     1141 aaaatccgct tgggatagaa gtttgaaaat ataagctctt actcttgtta tgtcggtaag
     1201 cattgagagt gtaccaattt gccctgattt taagtttaag atgctcaaga tctcagtaac
     1261 atcaatactt ctgtggtttt ctagctcttc atatgagccg agttcatact cataaaagca
     1321 gcaatgccca acttcttgat atgtattgaa agtcacaaag tctccgttga attcaaaaac
     1381 tagtttgtca ttaagcatat tttctttgat gtcaatatgt actctatcaa caagatatct
     1441 atgacaagct tccaataatc gaacttgatt taaatccatc acattcacct cctttctgcc
     1501 catattatag cagattagag gtactaaaaa cagatagaaa ggaggtgggg gaatgcagat
     1561 tcttctgtat aaactgcgaa aagaaaaaag aatttcacaa gaagagatgt ctaaggttat
     1621 taataagtct tctaacactt accgagataa agaattaggt aaaagagact tcacacagag
     1681 tgaaatgttt aaaatcgcca atttctttca caaagaatta ggcgaaattt ttacaccata
     1741 aacttcacga aacgtgaaat ataaatcaac acaacactag aaaggaacaa catgaatcaa
     1801 ctaataaaca tcaccctaaa cgaaaatcaa gaaccagttg tcagtggtcg tgatttacat
     1861 aaagtacttg aaatcaaaac agcttataaa gattggtttc caagaatggc tgaatatggt
     1921 tttgaagaag gtcaggactt tagctcattt ttgagcaaaa gtacaggagg tcgtcctagt
     1981 caagaccacg ttctaaaact agacatggca aaagagattg ctatgttaca gcggaatgaa
     2041 aaatctaagc aagtccgcaa gtattttatt caaatcgaaa aagactttaa cagccccgag
     2101 aaaat
//
LOCUS       DARYXZ010000108         2104 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYXZ010000108 DARYXZ010000000
VERSION     DARYXZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            99..500
                     /locus_tag="TV186_002011"
     CDS             99..500
                     /locus_tag="TV186_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1533354.1"
                     /translation="MAVKRKYIYVKGQKIYVPDEVYRAYKKGLNHETHLKRLDRKHGV
                     FRFGDFNTSIVDIADNTVDVEKIIETKMLIEDLYYALDSLNDEERKLIEALYFDDKTL
                     TEVAKQRDTNPMKISRLRNKILEKLRKFLDK"
     gene            956..1123
                     /locus_tag="TV186_002012"
     CDS             956..1123
                     /locus_tag="TV186_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1533355.1"
                     /translation="MCEEHNIDIKMEIDKKDKQTINQIDGWNIEVKFNENGLSLENLV
                     EEYIKEKFSVY"
     gene            1222..>2104
                     /locus_tag="TV186_002013"
     CDS             1222..>2104
                     /locus_tag="TV186_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019115678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1533356.1"
                     /translation="MFKDSVNKENIAVMYLRLSKEDGEKTESNSISNQREMINSYAKK
                     NQFIIIKEYVDDGYSGATFDRPNFKEMINDAYDKKFDTIIVKDLSRFGRDYIEAGKYI
                     QRIFPENGIRFISVNDNYDSKSADMNDTHLILPIKNFINDSYCRDISNKVKSSQKIKR
                     EKGDFISAFAPYGYKKSDENKNKLVVDEQAAPNIKNIFDMKLLGYSSKAIADELNHLG
                     VLTPRKYKESQGFKCNGFQNIKGGNWSAKSVNRIIENEVYIGNTLQGKSVTLNYKNKK
                     QIEREKEDWIRVENTHDA"
BASE COUNT          857 a          230 c          407 g          610 t
ORIGIN      
        1 ttttatttta gaggatcttg cacgtcaaaa tgcagaggtc ctcctttttt attcaaaaaa
       61 taagtttgaa atttttgata aaaaggaggg ctttacaaat ggcagttaaa agaaaatata
      121 tctatgtaaa aggtcaaaag atttatgtac ctgacgaagt gtatagagca tataaaaaag
      181 ggcttaatca tgaaactcat ttaaagagat tggatagaaa gcatggcgta tttcgttttg
      241 gagactttaa cacaagtatt gtagatattg cagataatac tgttgatgtt gaaaaaatca
      301 ttgaaacaaa aatgctgata gaagatctgt attatgcatt agacagttta aatgatgaag
      361 agagaaaact aattgaagca ctatattttg atgataaaac tctcacagaa gttgcaaaac
      421 aaagagacac aaatccaatg aaaatcagta gattaagaaa taagatttta gaaaagctga
      481 gaaaattttt ggataagtaa attaagtaga gggcagggaa acatctctgt cctctatttt
      541 tgaaaatttt tcaaaaatag tgttaaaagt tgtcctgaaa gtaaggttta tatatagagg
      601 gacttttatt acctcgttat atatagattt gatctttgac aactgaatag accaagacaa
      661 gactttaacc agtagtggag caatttataa acttacgcca agataaacct gctaagttaa
      721 attgatttaa atgaatacct acatttgtag aggatataag gtttggagcg ataaataagt
      781 ctgtataaaa agagggtggc aactcttgtg cgatgatact aatggggata atgatacttc
      841 tacagttgaa gccggctcat cttgaaaaga ggcggaggtg aaattcctat gtagcagcca
      901 atgcacttgt caatgtcata aaacttaaaa atattgaaga taaggagaag atattatgtg
      961 tgaagaacat aatatagata ttaagatgga aatagataaa aaagataaac agacaataaa
     1021 tcaaattgat ggttggaata tcgaagttaa atttaatgaa aatggattga gcttagaaaa
     1081 tttagtagag gaatacatca aagaaaaatt ttctgtctat taggggctga caaaaaatat
     1141 aaggagcgtt ataatatttt tgtggaagcc taaccttggt tcgatttatt gtatgtaaat
     1201 tgaatttaag gaggcttttt tatgtttaaa gacagtgtaa ataaagaaaa tattgcagtt
     1261 atgtatttga ggctttcaaa agaagatgga gaaaaaacag aaagtaattc tatatccaac
     1321 caaagagaga tgataaattc ttacgcaaag aaaaatcaat ttataattat caaagagtat
     1381 gttgatgacg gatattcagg agcaactttt gatcgtccta attttaaaga aatgataaat
     1441 gatgcttatg ataagaaatt tgatacgatt attgtaaaag acctatcaag atttggaaga
     1501 gattatatag aagcagggaa atatatacaa agaatatttc cggaaaacgg gataagattt
     1561 atatctgtaa atgacaacta tgatagtaaa agtgcggata tgaatgatac acatctaata
     1621 ctccctataa aaaactttat caacgacagc tattgccgag atatttccaa taaagtaaag
     1681 agttctcaga agataaaaag agaaaaaggg gattttatca gtgcttttgc accttatgga
     1741 tataaaaaat ctgatgagaa taaaaataag ttggtggttg atgaacaagc tgctcctaac
     1801 atcaaaaata tatttgatat gaagctcttg ggatattcct caaaggcaat cgcagatgaa
     1861 ttaaatcact taggtgtttt gactccgagg aaatataaag aaagtcaagg ctttaagtgt
     1921 aatggatttc aaaatataaa aggtggtaat tggtcagcaa agtcagtaaa cagaattata
     1981 gaaaatgaag tatatattgg gaacaccttg caaggcaaaa gtgttacctt aaactataaa
     2041 aataaaaaac agatagaaag agagaaagaa gattggataa gagtagaaaa tactcatgat
     2101 gcaa
//
LOCUS       DARYXZ010000109         2056 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYXZ010000109 DARYXZ010000000
VERSION     DARYXZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..902)
                     /locus_tag="TV186_002014"
     CDS             complement(<1..902)
                     /locus_tag="TV186_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1533357.1"
                     /translation="MSKLEEAKNILNELKVPPKQQSDLCGYVILAMADIKKNDEWANA
                     TNKWIRIHDVIAFIREFYEVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRY
                     RLTDEMLLLVKTFQSSLWEEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSP
                     GKHNQLQKFIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDV
                     VLYSEDKNWIYFVESVTSVGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSE
                     SLAWETEVWIADMPDHMIHLNGDK"
     gene            complement(895..>2056)
                     /locus_tag="TV186_002015"
     CDS             complement(895..>2056)
                     /locus_tag="TV186_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL1533358.1"
                     /translation="EYKVIKDNYITSQTLEYNNMLGVSTKPEKYDVIIGNPPYLKVGK
                     MANEALSMPDICYGSPNLYFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFL
                     NEVVLKHIHLFVSRDKVFDKESVLQETMIIKAKKELNKLKNITITTTNDNFDFGSKTV
                     FEASYDMVVSGEHKYVFLITDKEEADTIKKVNEWNDTLPTLGLKMKTGLTVDFRNQEA
                     LRNDAEEKAVPLFYSQHIKDGKVIFPVGKENEYLLTEKKGLLQENTNYLFVKRFTAKE
                     EKRRLQCGIYLAKKFPTYKAISTQNKINFITGLQGLSDCLVYGLYVVLNSTLYDNYYR
                     ILNGSTQVNATEINSMPIPPLTCIEDMGKELIKLKDMSEENCDEILGRFIYV"
BASE COUNT          642 a          407 c          244 g          763 t
ORIGIN      
        1 aatttatcac catttaaatg aatcatatgg tcaggcatat ccgcaatcca tacttccgtt
       61 tcccaagcta aagactctga gaatttttta aatgttttaa agtctaaaaa tgctgttaca
      121 tatattttcc cagctgaaac attttccgtc atttcttcaa tttcttttat tcgctttggc
      181 tccattgcac ccacagaagt tacagactca acaaagtaga tccagttctt atcttctgaa
      241 tataaaacaa catccggcat tttatcatgg agtgttatct caaagccgag ttcttttagt
      301 ttctcctcat tcttcaccaa atccttttga attgtgtcac caacatacaa acattcagag
      361 ttctcagcga atcgtggagc aaattcttca ataataaatt tctgtaattg attgtgtttg
      421 ccgggagaaa atgtaaaatc atctccgttt attttaacag gcatttttct taccgccttt
      481 ttagagctat atagatcaat taagttctga tgagatttta agaaattatt cttctgttct
      541 tcccacagac ttgattgaaa tgtttttact aataacaaca tttcatcagt taatcgatac
      601 ctgtaattag ggctatttgt tgctttccca ttatcttcaa taaatgctgc attcctaaaa
      661 tgatgcattg cctgtttacg gaatgtttct ctactattct ctgcatatga aacctcataa
      721 aactctctaa taaaggcaat aacatcatga attcttatcc atttattagt tgcattagcc
      781 cattcatcat tctttttaat atctgccatt gccaaaataa catatccaca tagatccgac
      841 tgctgttttg gtggaacttt caactcattc aaaatattct ttgcttcttc taatttagac
      901 atatataaat ctccctaata tttcatcaca attttcttca gacatatcct ttaatttaat
      961 cagttccttt cccatatcct caatacaagt tagtggtgga attggcatcg agttaatttc
     1021 agtagcatta acttgagttg atccatttaa aattctgtaa taattatcat aaagcgtaga
     1081 gttcaataca acatacaaac cataaaccaa acaatctgat aatccttgta agcctgtaat
     1141 aaaatttatc ttattctgtg tgctaattgc cttatatgtt ggaaattttt tagctaaata
     1201 aattccacat tgtaatctac gcttttcttc ctttgccgta aatcttttca caaataaata
     1261 attagtgttc tcctgcaata atcctttttt ctccgttaat agatactcat tttcttttcc
     1321 aacaggaaaa atcactttac catcttttat atgttgcgaa taaaataaag gaactgcttt
     1381 ttcctctgca tcatttctta aagcctcttg atttctaaaa tcaactgtca aaccagtttt
     1441 cattttcaag ccaagagttg gcaaggtatc attccattca tttacctttt taatcgtatc
     1501 agcttcttct ttatcagtta tcaaaaaaac atatttgtgt tctccggaaa caaccatatc
     1561 gtaagaagct tcaaaaacag tcttgctgcc gaaatcaaaa ttatcattcg ttgtagttat
     1621 agtaatgttt tttaacttat ttaattcttt cttggcttta ataatcatag tttcttgcaa
     1681 aacagactct ttatcaaaga ctttgtctct gcttacaaat aaatgaatgt gcttcaaaac
     1741 cacttcattt aaaaacttct cacgaaactt tttaaagtac gctccagaag tccatgatct
     1801 tggaacgata aacaccaatt cgccattatc aaccaaattg aaacttgcca tctccataaa
     1861 aagaaaatat aaattcggtg atccataaca aatatcaggc atggataaag cttcattagc
     1921 catttttcca acctttaaat aaggtggatt tcctataatt acatcgtatt tttcaggttt
     1981 agtactcacc cccaacatat tgttatattc aagtgtttga cttgttatat agttatcttt
     2041 aatcactttg tattca
//
LOCUS       DARYXZ010000110         1906 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYXZ010000110 DARYXZ010000000
VERSION     DARYXZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1906
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            57..644
                     /locus_tag="TV186_002016"
     CDS             57..644
                     /locus_tag="TV186_002016"
                     /inference="COORDINATES: protein motif:HMM:TIGR02185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1533359.1"
                     /translation="MSNKLKGKDLITIGIYTAIYFVINFAFMLAGMIPVMWIMMPSLI
                     ALFTGVPYMMICNKVQKAGAILIMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRA
                     ITRYTSFIGNTLSFALFSIGMIGSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSP
                     AILIGVIILTFICSLVGALIAKRMMNKHFKKAGII"
     gene            646..1317
                     /locus_tag="TV186_002017"
     CDS             646..1317
                     /locus_tag="TV186_002017"
                     /inference="COORDINATES: protein motif:HMM:NF014420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1533360.1"
                     /translation="MREYRLKIDPRAGISLLFILNFTIFNVSTVYALFVLLIWNCVYA
                     MCNGYCRIAIKFIFTYWLLYLIEFLVLPKLPSLIAISFAILLTYILKMLPVALFGYVF
                     VKTTSLYELITALRKIHFPESIITGLSITLRYFPALREDFHKTYDAMKLKNMSVLEKI
                     SGLIITTMTRATLNIEELSQAASVRGIDNPVKKFSAAEINFKTSDAVVFIVSSVVYIF
                     ICVRY"
     gene            1331..>1906
                     /locus_tag="TV186_002018"
     CDS             1331..>1906
                     /locus_tag="TV186_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533361.1"
                     /translation="MVELKNISYSYSKENQILQDINIKIQDGECILLCGRSGCGKTTI
                     GRIINNLIPRFFERGVMSGDVYINNENTKDFEMHELANLIGTVFQNPKAQFFHTNSDA
                     EIVFGLENNGMKPEKIRRRYKEVVDELNIHDLTNRDMFSISGGQKQIIAFASIYAMNP
                     KVYVLDEPTANIDKKTIIKIGKIIEKLKKRGH"
BASE COUNT          691 a          208 c          347 g          660 t
ORIGIN      
        1 aaaagaatta attaaagaat ttttattaaa aactacgatg acagaggaga ataataatga
       61 gcaataagtt aaaaggaaaa gatttaataa caataggcat ttatacagca atttattttg
      121 taataaattt tgcatttatg ctagctggaa tgataccagt tatgtggatt atgatgcctt
      181 cactgatagc tttatttaca ggggtgccat acatgatgat ttgcaacaaa gttcaaaaag
      241 ctggtgctat tttaatcatg ggaacagtta cagttttgat atattatgca acaggacaat
      301 ttacaacagt tattcttgca acttttgcag taggttgtat attagctgaa attattagag
      361 caattactag atatacaagt tttataggga atactttatc atttgcacta ttttcaattg
      421 gaatgatagg atcgcctctt cctatttggt tgtttaaaga atcatttttt gctcatatat
      481 cagaggttgg tatgtcgcag gattacataa atgccttgga aaagtttact tcgccagcga
      541 ttttgatagg agttattatt ttgactttta tttgttcgtt agttggggct ttgattgcga
      601 aaagaatgat gaataaacat tttaaaaaag cgggaattat ataaaatgcg tgaatataga
      661 ttaaaaatag atccgagagc agggatttcc ctgcttttta tcttaaactt tacgatattt
      721 aatgtatcca cagtttatgc attatttgtg ctattaattt ggaactgtgt ttatgcaatg
      781 tgtaatggat attgtaggat agcaatcaaa ttcattttta cttattggtt gctttatttg
      841 atagaatttt tggttttacc gaaactacca agtttaattg ctatttcctt tgctattcta
      901 ttaacttata ttttaaagat gttaccagta gcattgtttg gatatgtttt tgttaaaact
      961 acaagtttgt atgagttaat tacggcactt agaaaaattc attttccaga aagtataata
     1021 acgggattat caataactct tagatatttt ccggcattaa gagaagattt tcataaaaca
     1081 tatgatgcta tgaaactaaa aaatatgtct gttttagaaa aaataagtgg actgataatt
     1141 actacaatga caagagccac attaaatata gaagaattat ctcaggcagc aagtgtaaga
     1201 ggcatagata atcctgtaaa aaaattttct gcggctgaaa taaattttaa gacaagtgat
     1261 gcggtagtgt ttatagtgtc ttctgttgtc tatattttta tatgtgttag gtattgactg
     1321 gaggatagat atggttgaat taaaaaatat ttcatattca tattcaaaag aaaatcaaat
     1381 attacaagat ataaatatca aaatacagga tggagaatgt attttgttat gtggaagaag
     1441 tgggtgtgga aagacaacaa taggtaggat tataaataat ttaattcctc gtttttttga
     1501 aagaggagtt atgtcaggtg atgtttatat aaataatgaa aatactaaag attttgaaat
     1561 gcacgagcta gctaatttaa ttggaaccgt ttttcaaaat cctaaggcac agttttttca
     1621 tacaaattcg gatgcagaaa ttgtatttgg tttagaaaat aacgggatga aaccggaaaa
     1681 aataagaaga agatataagg aagttgtaga tgaattaaat atccatgact tgacaaatag
     1741 ggatatgttt tcgatttcgg gtggacaaaa acaaataatt gcatttgctt ctatttatgc
     1801 aatgaatcct aaggtgtatg ttttagatga accaacagca aatattgata aaaaaacaat
     1861 tataaaaata ggaaaaatca tagaaaagct aaagaaaaga ggacat
//
LOCUS       DARYXZ010000111         1864 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYXZ010000111 DARYXZ010000000
VERSION     DARYXZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1864
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..371
                     /locus_tag="TV186_002019"
     CDS             <1..371
                     /locus_tag="TV186_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="equibactin biosynthetic protein"
                     /protein_id="HEL1533362.1"
                     /translation="QIESKVDFIIAVGVLNNAKNIEKTLSYIRGFLKDDGFLIIVEAV
                     DESPEILISQVFMMSEPDDVRMKKNITFLKMEQWMEIFKNQRFELILFEPGYENYLEN
                     FNQKLFVLKKNRGENHENRE"
     gene            355..>1864
                     /locus_tag="TV186_002020"
     CDS             355..>1864
                     /locus_tag="TV186_002020"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012873.1,HMM:NF036900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533363.1"
                     /translation="MKIENKLIELYRKGLEVFIEGDKLKYKSTCGMPSEEDIEFLKIN
                     KTSIIDILNKNDGASRYSLDIDELPLTEIQSAYLLGRRNHFELGGVASHVYMEVILPL
                     LDIDRAEKVWNDIILKHDALHSIFTSNNTQKVLKEFAYYKIECNEGADIKEKIALTRD
                     KLKGKSYNADIWPLFDISVSQLDDNSLLHLSFDFLILDWASIWILLKEFEECYFDGKT
                     IMDNSYDLKEIRTSQLKLKHSSKYLSDKDFWERRIPFLPDAPLLPIKNKIVKNGFERI
                     QLRIDENTWSKIKSNISEIGVTQTSFLVTILALVLNRWSSNSEFTINLTTMNRPKEYI
                     KSDVVNDFTSTELLEFRMESLQPFYVLLKHIQQQMIEDLQHETFTGVEVTREVRKNVE
                     RRDAIFPFVFTSALGIKASEYKYISLQKEGLSETPQVLMDCQVMEVNHELIINFDLRA
                     DAFSKELSNSIAEDYSNLLNCFFDLEYFKKTLTEMYDENEMNDVLADKSDFDR"
BASE COUNT          729 a          196 c          337 g          602 t
ORIGIN      
        1 aacaaattga aagcaaagta gattttatta tagctgtagg agtgctaaac aatgctaaaa
       61 atattgaaaa aacattgagc tatataaggg gatttttgaa agatgacggc ttcttgatta
      121 ttgtagaagc agtcgatgaa tctccagaaa ttttaatatc tcaagtattt atgatgtcag
      181 aaccagatga tgttcgtatg aaaaaaaata tcactttttt gaaaatggag caatggatgg
      241 aaatatttaa aaatcaaagg tttgaattaa ttctatttga gccaggatat gaaaattatt
      301 tagagaattt caatcaaaaa ttatttgtgt tgaaaaaaaa tagaggtgaa aatcatgaaa
      361 atagagaata aattaataga gttgtacaga aaaggtcttg aagtatttat tgagggagat
      421 aaattaaaat acaaatctac ttgtggtatg ccctcggaag aagatataga atttttaaaa
      481 ataaataaaa cttctattat tgatatattg aataaaaatg atggtgcttc tagatattca
      541 ctagatattg atgaattacc tttaacagaa attcaaagtg catatttatt aggtagaaga
      601 aatcattttg aacttggtgg tgttgccagt catgtttata tggaagtaat attacctcta
      661 ttggatatag atcgagctga aaaggtttgg aatgatataa tactaaagca cgatgcatta
      721 cattcaatat ttacatcaaa caatactcag aaagtactga aggaatttgc ttactataaa
      781 atcgaatgca atgagggtgc agatataaaa gaaaaaattg cattaacaag ggataaactt
      841 aaggggaaaa gttataatgc agatatatgg ccactattcg atataagtgt aagtcagtta
      901 gatgacaata gtttattgca tttatcattt gattttttga ttttagattg ggcaagcatt
      961 tggattttat taaaggaatt tgaagagtgt tattttgacg gaaagacgat tatggataat
     1021 tcttatgatc ttaaagaaat aagaacgagt caacttaaac tgaaacatag ttctaagtat
     1081 ttatcggata aagatttctg ggaaagaaga attccttttt tgcctgacgc tccactatta
     1141 ccaattaaaa ataaaatagt caaaaatggt tttgaaagaa tacaacttag aatagatgaa
     1201 aatacttggt cgaagataaa atctaatata agtgagattg gtgtcacgca aacatctttc
     1261 ttggtgacaa tattagctct tgttcttaat agatggagtt ctaattctga atttaccatt
     1321 aatttaacaa ctatgaatag accaaaggag tatataaaga gcgatgttgt taatgatttt
     1381 acatctacag aacttttaga gtttagaatg gaatctctgc aaccattcta tgttttatta
     1441 aaacacatac aacagcaaat gattgaagat ttgcaacatg aaacatttac aggagtggaa
     1501 gttactcgtg aagttaggaa aaatgtagaa aggagagatg ctatatttcc atttgttttc
     1561 acaagtgcat taggaataaa agcttcagaa tataaatata ttagtttaca aaaagaaggt
     1621 ttgagtgaaa ctcctcaagt attaatggat tgtcaagtaa tggaggtaaa tcatgaacta
     1681 ataattaatt ttgacttaag agcagatgct ttttcaaaag aattatcaaa ttcaattgca
     1741 gaagactatt ctaatctatt aaattgcttt tttgatttag aatatttcaa aaaaacactg
     1801 acagaaatgt acgatgaaaa tgagatgaat gacgttttag ctgataagag tgattttgat
     1861 agag
//
LOCUS       DARYXZ010000112         1853 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYXZ010000112 DARYXZ010000000
VERSION     DARYXZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1853
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            11..1432
                     /locus_tag="TV186_002021"
     CDS             11..1432
                     /locus_tag="TV186_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL1533364.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHNFDAIVYKLHGDVETPE
                     DAVITRSDYEEFGYNKRKLFREVLEGDLLTKTFLFLGFSFEDPNFNYVIGRLRVLLDE
                     KNTRKHYCIMKRVQDADEDYEYKKARQELQIEDLNRYGIFTYLVNKYDEITEILSTLV
                     DRFRRKTIFISGSAYSYSAYSQKTGENFIHKLSFELSKNGYHIVNGYGKGVGEFVLNG
                     VADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKLYKENREQMIESCGIAIFLFGNKEA
                     EDIASGVMDEYELSKKHGLVCLPIEYTGGASKEIYDQTTQEISDKNTISAIEQANKQC
                     DGDIDMSVKNIVQAVKILNKEEF"
     gene            1433..>1853
                     /locus_tag="TV186_002022"
     CDS             1433..>1853
                     /locus_tag="TV186_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL1533365.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     KTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSK"
BASE COUNT          728 a          193 c          371 g          561 t
ORIGIN      
        1 aagggaggag gtgtttatta ttaaaggtga agtatccaga aaagatttga ttagagaaat
       61 tgaaaaagct attaaaagtg atgaattagg agcatttatt ggagcaggat tatcaattcc
      121 tgccggattt tgtagttgga aagaacttct aagagaacct gcagaagaaa ttggattaga
      181 tgttgaaaaa gaaagtgatt tggttaactt ggctcagtat tattctaatt caaaaaagag
      241 aacatcaata gatgacttga tcaaaggtca attttctcaa ttagtaaagc ctactgaaaa
      301 tcataaatta ttgtcgcagc tgcccatttc aactttttgg acaacaaatt atgataagtt
      361 aatagaaaaa gctttagaaa ataatatgaa aaagccttat gtaaaaacaa aggatgaaca
      421 attaagaggt acaaatcata attttgatgc gatagtatat aagctgcatg gtgatgtaga
      481 aactcccgaa gatgcagtaa taacaagaag tgattatgaa gagtttggat ataacaaaag
      541 aaaattattt agagaggttt tagaaggaga tttgcttact aaaacatttc tatttttggg
      601 atttagtttt gaagatccaa attttaacta tgtaattgga aggttaaggg tcttactcga
      661 tgaaaaaaat acaagaaaac attattgtat tatgaaaaga gtccaagatg ctgatgagga
      721 ttatgaatac aaaaaagcaa gacaggagct acaaattgaa gacctaaata gatatggtat
      781 ttttacatat ttagtaaata aatatgatga aatcaccgaa atattgagca ctcttgtcga
      841 tagatttaga aggaaaacaa tatttatatc tggtagtgcg tactcctatt cggcttattc
      901 tcagaaaact ggcgaaaatt ttattcataa actatctttt gaactatcaa aaaatggtta
      961 tcatattgtg aatggatatg gtaaaggagt cggtgaattt gtattaaatg gagttgcaga
     1021 ttattgtttg actcacaagt ccaaaataaa tgatttttta acacttatgc cttttcctca
     1081 aaatagttca ttaggtattg atttagataa gctatataaa gaaaatagag agcagatgat
     1141 tgaaagttgt ggtatagcta tatttctttt tggtaataag gaggcagaag atattgcaag
     1201 cggagttatg gacgaatatg agttatcaaa aaagcatgga ttagtatgtt tgcctattga
     1261 atatactggc ggtgcatcta aagaaatata tgatcaaaca actcaagaaa tttcagataa
     1321 aaatacaata agtgcaattg aacaggcaaa taaacaatgc gatggcgata ttgatatgtc
     1381 tgttaaaaac atagttcaag cagttaaaat attaaataag gaggaatttt aaatggcaaa
     1441 aagacaggta ttttttagct ttcattacga caatgataat tggagggcag gacaggttcg
     1501 caatatgggg aaagtagaca gtagttctac cttttctgat aatgactggg aggaagtaaa
     1561 agaaaaaact gaaagtaaaa ttaaagaatg gattgatgaa cagttaaata agcgttcatg
     1621 tttggttgtt ttgattggag aaaaaacagc gaacagaaaa tggataaatt atgaaataag
     1681 aaaagcatat gagttaaata aaggtattgt gggaatttat attcacaagt tggagaattc
     1741 actgggagag caagatgata agggtaataa tccttttgat tatttaacat tagaaggtga
     1801 aaaactttca aagtatgtta aatgttttga ctccaactat tcatcaagta aat
//
LOCUS       DARYXZ010000113         1598 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYXZ010000113 DARYXZ010000000
VERSION     DARYXZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1598
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            81..638
                     /gene="efp"
                     /locus_tag="TV186_002023"
     CDS             81..638
                     /gene="efp"
                     /locus_tag="TV186_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL1533366.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            681..1070
                     /locus_tag="TV186_002024"
     CDS             681..1070
                     /locus_tag="TV186_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1533367.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1063..1515
                     /gene="nusB"
                     /locus_tag="TV186_002025"
     CDS             1063..1515
                     /gene="nusB"
                     /locus_tag="TV186_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL1533368.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
BASE COUNT          480 a          288 c          371 g          459 t
ORIGIN      
        1 aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac gataactatt
       61 ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt atgacgtttg
      121 aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca ggtaagggaa
      181 acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc gacacaacct
      241 atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct caataccttt
      301 acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag tatgagattc
      361 cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat gtgaaaatcc
      421 agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag ttgactgtta
      481 cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag cctgcaaccc
      541 ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa aagctaatca
      601 tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg aattagtcta
      661 agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt atttcgccac
      721 gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt cactcgcttc
      781 acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc gtctatcttc
      841 agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa tatggtgtaa
      901 aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt tatgacatgg
      961 ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct gaaaagacac
     1021 caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa gcattttcaa
     1081 cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat ggagatgggc
     1141 ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc agctgatgac
     1201 aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt tatggatcat
     1261 aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc cattgagcgc
     1321 ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac cctgtttgag
     1381 gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa atattctgat
     1441 gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga tgagtcagct
     1501 gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc tatagggctt
     1561 tttgaatgct caaaaacgtc tcatctggtt ggctatgt
//
LOCUS       DARYXZ010000114         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYXZ010000114 DARYXZ010000000
VERSION     DARYXZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            71..1468
                     /locus_tag="TV186_002026"
     CDS             71..1468
                     /locus_tag="TV186_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL1533369.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYXZ010000115         1421 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYXZ010000115 DARYXZ010000000
VERSION     DARYXZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1421
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..265)
                     /locus_tag="TV186_002027"
     CDS             complement(<1..265)
                     /locus_tag="TV186_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1533370.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWDESI"
     gene            complement(382..753)
                     /locus_tag="TV186_002028"
     CDS             complement(382..753)
                     /locus_tag="TV186_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEL1533371.1"
                     /translation="MFIFLRQLIQTQDGKILFTLGAIAVAMMIDFLTGTVAAKINPNI
                     DFRSKEGINGILRKICSIALMIFFIPLSILLPNDTGVAFLYVMYVGYLLFELKSILEN
                     LNKMGIDVALFKQFIDMFSKK"
     gene            complement(765..1376)
                     /locus_tag="TV186_002029"
     CDS             complement(765..1376)
                     /locus_tag="TV186_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1533372.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHVIITAEDGSVISQPIKQDLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTATTAQAAAGLAKVS
                     AERTQKMINLQTIHMLTSVDKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKHEDL
                     AGEGNLVFVYVNEAFTYDKQTLKDLESEDKVTVIKYADLVKGK"
BASE COUNT          374 a          326 c          270 g          451 t
ORIGIN      
        1 ggatcgactc gtcccagcta tcataggccc taaaacgatc tacaatatcc gttacaacac
       61 ccggctgata ctcctcctga gtttttgtat taaatgactt acccgtccaa gagctatctg
      121 ccttgatacc aaatagagcg ttatgtgggg cgtacttgcc ccaaccactc tcaaggattg
      181 cctgtgctgc ggtcaacgat ggcaagattt tatactttgt ccagccatct aagcagcctt
      241 gcttaatgtc atctaaaaag gtcatctgtc ctccttatct aaaaacggat aaacaatcag
      301 agcaatcaca gacagcggca catatagcac tgcgattgct aggactattg ctaatcgtgt
      361 gattgctcgc atgagatcct cctatttttt actaaacata tcaataaatt gcttaaacag
      421 tgcgacatca atccccattt tgtttagatt ttctaagatt gattttagct caaagagcag
      481 atagccaacg tacatgacat acaaaaaggc tactcctgta tcatttggca gtaaaatcga
      541 caaagggata aaaaagatca tcagggcaat tgagcaaatt ttgcgcaaaa taccattaat
      601 cccctctttg ctcctaaaat caatgttggg gttaattttt gctgcaacgg tacccgttaa
      661 aaaatcaatc atcattgcga ctgcaattgc tcctaaagta aataggattt taccatcttg
      721 ggtctggatt aattgtctca aaaaaataaa catggatcac ctcactattt gcctttaacc
      781 aaatcagcgt atttaatcac tgtgacttta tcctctgatt ccagatcttt gagggtttgc
      841 ttgtcatagg taaaggcctc attgacatac acaaagacaa gattgccctc accggccaaa
      901 tcctcgtgct tgtcgtctag cacagtaaaa acgtcgtgct cctgatactg accttttttg
      961 gctggctcga taagctctag catgcctttg taaatgtcag gctcgatctt atcgacgctg
     1021 gtcaacatgt ggatagtttg caagttaatc atcttttgcg tgcgctctgc ggacacttta
     1081 gccagaccag ctgccgcttg tgcagttgtt gctgtcttag cagtttcctg cgatagtttt
     1141 tccaagtcgt ccactttttg caccgcttcg cccatggcga tttccacgta ttcggatttt
     1201 ttaaattctt ccaaggtagc tttgatgatc tctgtgtcat tagttgaggt taagtcctgc
     1261 ttgattggtt gagagatgac tgagccatcc tctgctgtaa taataacgtg agtgcttgcg
     1321 actgctcctg tgctgtcaaa ttgtgggtat tttcctgtga ctttccaatt gcgcataatt
     1381 tactctcctt ttttatttgc ttcgtactgc tctaaaatgt t
//
LOCUS       DARYXZ010000116         1353 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYXZ010000116 DARYXZ010000000
VERSION     DARYXZ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1353
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..499
                     /locus_tag="TV186_002030"
     CDS             <1..499
                     /locus_tag="TV186_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533373.1"
                     /translation="KKDLSSTNDFEVIKMVLDEFKKSEYVEIAMGEAVQKVDDLEKLS
                     QETAKTATTAQTAAGLARAAAERTQKMINLQTIHVLTTSDKVEPDIYKGMLELIAPAK
                     KGQYQEHDVFTVLDDKHEDLAGEGNLVFVYVNEPFEYDKQTLKDLESEDKVTVIKYAD
                     LVKQD"
     gene            510..800
                     /locus_tag="TV186_002031"
     CDS             510..800
                     /locus_tag="TV186_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533374.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANELAMAQLKD
                     SIKELAYELKNLDRDREITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            803..982
                     /locus_tag="TV186_002032"
     CDS             803..982
                     /locus_tag="TV186_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533375.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVTSTVIM
                     SGIVCVLMNVSDIKE"
     gene            1094..>1353
                     /locus_tag="TV186_002033"
     CDS             1094..>1353
                     /locus_tag="TV186_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1533376.1"
                     /translation="MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPYNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWEES"
BASE COUNT          439 a          245 c          326 g          343 t
ORIGIN      
        1 aaaaaaagat ctgtcatcta caaatgattt tgaggtcatt aaaatggtcc tcgacgagtt
       61 taaaaaatca gagtatgtcg aaatcgcaat gggcgaggca gtccaaaaag tggacgactt
      121 ggaaaaacta tcgcaagaaa ctgctaagac agcaacaact gcacaaacag ccgctggttt
      181 ggccagggca gctgcagagc gcacacaaaa gatgattaac ttgcagacta tccacgtttt
      241 gacaaccagc gataaagtcg agcctgacat ctacaaaggc atgcttgagc ttattgcgcc
      301 ggccaaaaaa gggcaatatc aagagcatga tgtctttacg gtgctagacg acaagcatga
      361 ggatcttgca ggcgagggca atctcgtctt tgtgtatgtc aacgagccgt ttgagtatga
      421 caaacaaacg ctcaaagact tggagtctga ggacaaagtc acagtcatta aatatgcgga
      481 tttggtaaaa caagattaga ggtggttaga tgatagattt tgtacaaatt ggtgcttttt
      541 gtggcgctgc tttgtctatc ttgggtgttt ggggatttat cgtcaatccc tttaaaaaag
      601 ccatggaagc taacgagcta gccatggccc aactcaaaga ctcgatcaag gagttagcct
      661 acgagctaaa aaatcttgat cgcgataggg agataaccaa aaagattatc gatcggcatg
      721 aggagcgttt aggacgtgta gaggacgaca ttattgtcaa taaagagcaa atcaaaacat
      781 tatttaaaaa aggagactaa aaatggataa atggtttaaa aaagtagcaa tcaaaacaat
      841 taagacaatg gcccaaaccg ctgtaggggt tattggatca agcgcattga ttactgacgt
      901 caactggcag gtggtgacct caacagttat tatgtcaggt attgtctgcg tcttgatgaa
      961 tgtgtctgac atcaaggaat agcattatgc gagcaatcac acgattagca atagtcatag
     1021 caatcacaat actgtattta ccgctatctg tgattgctct gattgtttat ccgtttttag
     1081 ataaggagga cagatgacct ttttagataa gattaagcaa ggctgcttag atggctggac
     1141 caagtacaaa atcttgccat ctttaacagc agcacaggca atccttgaga gcggttgggg
     1201 taagtatgcc ccatataacg ctctatttgg tatcaaggca gatagctctt ggacgggtaa
     1261 gtcatttaac acaaaaactc aggaggagta tcagccgggt gttgtaacgg atattgtaga
     1321 tcgttttagg gcctatgata gctgggagga atc
//
LOCUS       DARYXZ010000117         1351 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYXZ010000117 DARYXZ010000000
VERSION     DARYXZ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1351
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..1154
                     /locus_tag="TV186_002034"
     CDS             <1..1154
                     /locus_tag="TV186_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1533377.1"
                     /translation="KLEKYDQTTLENMGENEKQVGIKADKEAISKFTSLTLNGKKYTD
                     KKQAGEFLINKIKGIKKLDDFRSEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENHY
                     GEFGTDEIGNITRMDNVLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLKE
                     KTLRLAEVNNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFPD
                     LTDIGLAYTTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELIQ
                     IKTNIGFWDFNELVYVDEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFRD
                     SKVQSFGDLDKKEKASVMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
BASE COUNT          567 a          159 c          280 g          345 t
ORIGIN      
        1 aaaaactaga aaaatatgat cagactactt tagaaaatat gggtgaaaat gaaaaacaag
       61 tggggataaa agcagataaa gaagcaatat caaaattcac atctttaact ttaaatggga
      121 aaaaatatac cgataaaaag caagccggag agttcttaat aaacaagata aaaggaataa
      181 aaaaattaga tgattttcgt tctgaggaag taaaaatcgg agaatataga aatttcgatt
      241 tgttcgcata ttatgacagg ttctccaatc agtataaatt caatctgaag ggagaagaaa
      301 atcattatgg ggagtttgga acggatgaaa tcggaaatat cacccgaatg gataatgtac
      361 ttgataggat gcctgagaga ttggagcaga cacttggaaa acttaaagat accgagaatc
      421 aacttgaaac ggcgaagctt gaaataaaaa agaaatttcc acaggcagag cttttaaaag
      481 aaaagacgtt aagacttgct gaggtaaata atttgcttga tatgggacaa aaaggagatt
      541 taaaagagga gaaaaatcca cttttggaag aagtgaagga agaactgatt cattttctaa
      601 ataaagaata tgatgaagca cacagtatag aagatttcga tacaatgttt cctgacttga
      661 cagatatagg tttggcatat acgactacac cggatgaaaa gcatgagata cagacaagtc
      721 ttgatttaat caattacaag atgaacactt atgtagacaa tactttaatt gacagttttc
      781 agtatactta cgatccactt aatgcaagtg atacgaagga acttatacaa atcaaaacga
      841 acataggttt ttgggatttt aatgagctgg tatatgtgga tgaagaaaag ttaaaagcat
      901 cacttggact tgaaattgat gacgatggta atttctatga tccgctttca aaggatatgg
      961 atttagatgg agtaatggac aggtatgatg cagactttag agatagtaaa gtacaaagtt
     1021 ttggagattt ggataaaaaa gaaaaagcat ccgtaatgga taggcttgga tacttcaaag
     1081 aaaagataaa gaaaggaggc ctacaaaatg aaaatattga tagaaagata gagtgtaagg
     1141 aggaggttag atagttggaa tatcacaaaa atattagagc aacggataga gaaatgcaga
     1201 aactttttga aaatgaggag tataactatt ccgtaagata ttttgaaaaa atagaagaaa
     1261 acttatttaa aacgataatt cgcacaccgg agaatataga gtttccaaaa tccaaaacct
     1321 tgtctataaa cacgataaaa aaactcttag a
//
LOCUS       DARYXZ010000118         1288 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYXZ010000118 DARYXZ010000000
VERSION     DARYXZ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            85..1288
                     /locus_tag="TV186_002035"
                     /pseudo
     CDS             85..1288
                     /locus_tag="TV186_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
BASE COUNT          392 a          309 c          242 g          345 t
ORIGIN      
        1 gggttatagg gctttatgag tatcaaaaaa gtcccatatg acctataatg aaaagcgact
       61 aaactatcat ttagaaagac tcatatggaa caatcacatg ttatcacaca actactggga
      121 attaaagacc ctcatatcac attctccaaa gaaatacacg acatgaaaac tcataaggaa
      181 ttgaaagctg tccttgacta cgatgcccca ccttgcccta actgccaaag tcagatgggc
      241 aagtacgact tccaacggga atccaaggtc ccttttctcg attgcgcagg ctacaagact
      301 ttgattcgcc tcaaaaagcg ccgtttcaaa tgtcagtttt gcggaaaaat tactgtcgct
      361 gagacttctc tagtccctaa aaaccatcaa ataccaacca tcgtcaaaca gaaggtggcc
      421 cagcttctca tcgagaaagt ctccatgacc gctatcgctg atagactatc catctccacc
      481 tcaaccgtca tgcgaaagct caacgagttc acgttcaagt ctcatttgac ttatttaccc
      541 gaacatatgt cctgggatga atatgccttt aagaagggca agatgagctt tattgctcag
      601 gactttgaca ccaacaacat catcgctatt ttggatggac ggacgaaagc tgtcattcgc
      661 aaccacttcc tgagatatcc tcggcaggtc agaaacgacg ttaaactcat caccatggat
      721 atgtttaccc cctattacaa cctggctaag atgcttttcc caaacgctta gattgtcctt
      781 gatcgtttcc acattgtgca acatttggga cgtgccatga accgtatccg tactcaaatc
      841 atgaactctt ttgatcgaaa atcccacgaa tacaaggctt tgaaacgtta ctggaagctg
      901 attcaacaag atagtagcaa acttagtgac aagcgttttt accgcccgac ttttcgcatg
      961 catttgacaa acaaggaggt ggtcgagcgt cttttgagct actctgacga gcttagaaag
     1021 cattatgacc tttatcagct tctgcttttt cacttccagg aaaagcaagc tgaccacttt
     1081 ttcggcctga ttgaggagca gatagacagt agcaatcctc tctttcagac cgttttcaag
     1141 acctttttga aagacagaga caagattgag aacgcactgg atttgcctta ttctaacgct
     1201 aaactggagg ctaccaataa tctcatcaaa gtcatcaagc gcaatgcttt tggatttcgg
     1261 aactttgaaa actttaaaag acggattt
//
LOCUS       DARYXZ010000119         1281 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYXZ010000119 DARYXZ010000000
VERSION     DARYXZ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1281
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(228..722)
                     /locus_tag="TV186_002036"
                     /pseudo
     CDS             complement(228..722)
                     /locus_tag="TV186_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(948..1020)
                     /locus_tag="TV186_002037"
     tRNA            complement(948..1020)
                     /locus_tag="TV186_002037"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(985..987),aa:Lys,seq:ctt)
     gene            complement(1022..1215)
                     /gene="ssrS"
                     /locus_tag="TV186_002038"
     ncRNA           complement(1022..1215)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TV186_002038"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
BASE COUNT          376 a          226 c          222 g          457 t
ORIGIN      
        1 gaggttgtga caatcgagcg gatatccgat gttatggcag aactttctga gtctgaataa
       61 ttttagttca ccaaagaatc aagaaagaac cattggggca aaattggggc ataagtttag
      121 aacttttgtc gtttcttgtg tcgatacaat accggtttaa tactaacaaa tgcttttatt
      181 atcgactttg taaccattat tgttccttgt gttttttcgg gaataaactc aagaagtttt
      241 tgagtttttt cttgaatttc tttttcatat ttcaatatga tgagtgaaat tttatcttct
      301 ttggacatag tgttgttgtc ttcaagatta agttctttag ttgttagagt gtttttatct
      361 aatttatttt gaaatattgc aaaatctaga attttttgaa gtaatacttc ttcctcggcc
      421 atacggctat aaagccaatt attttcgagt ctctctaggt gctccatcca cttaaagtct
      481 cttttttctc ctaacatatt gtagggaaat aaggtatcaa tatcaacatt taaggctgta
      541 gcaatctctt gaagcctatc ccatgaaggt tcagtagtcc ccttttcgtc attaataatt
      601 gtttgcttag taactcctat taatttagcg agttcttttt gtgtttttcc agcttttaag
      661 cgagcatttt taatatctat ttgtccaact gttaaagcct gcgaataatt aaaaaaagcc
      721 atttttctcc aaattccgtc gcaggtgatg gaggtgaaaa tactccgatt gtatcacctt
      781 gtgttaatta tattattgtc atgtgttagc tctcttttta aaaagtaata aattctttat
      841 ttaacatcat atcataaaaa attgtttcgg ggacaaatgg tgggacaaac cctctttagg
      901 caagcaaaaa agccctgcaa taaaggcttt ttgtcgtttt tacactatac cccctacagg
      961 gctcgaacct gtgacccata gattaagagt ctactgctct accaactgag ctaaggaggt
     1021 aaggaaagct gtattggcac cggtgattca cgttttgtat tgaacccgca cgatataagc
     1081 aggtgggcaa catacttctc ttcagattgc ttccacgtga aacggcttgc atactagaga
     1141 tagactttgt ttccctaaaa tacaaaaaaa tagtcggtca acacttagat gtgaattcgt
     1201 atgccacagc aataactcta tgctcttatg ataccacttt ttgaaaattt ttcaagccct
     1261 aaaatgaaaa aaagatcgta t
//
LOCUS       DARYXZ010000120         1159 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYXZ010000120 DARYXZ010000000
VERSION     DARYXZ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>1159)
                     /locus_tag="TV186_002039"
     CDS             complement(<1..>1159)
                     /locus_tag="TV186_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL1533378.1"
                     /translation="ETMKKLRNLLTNNGKLIVVEPKERIRIQDITTSILNNFAGYNDN
                     IFNVDEWNSIFYDANLNCCKQISVGGSIVYILEKRIQFVDIETIKAKMRNMVPIYMVP
                     DDIVLLKNMPQNKNGKVDRKKLEEIYKDKKLQGNIFDMILDDREIETLKDIWKEIFGY
                     DTKYRTSFFSNGGDSLIATKLSAKIEEKFKISFSIKDVMENITIEAQAQVIKDRIAEQ
                     RFADKISVIEETITEEEFDLTDVQHAYYVGRNKDMILGGVSTHCYFEIESSDIDVNKL
                     EKAWNYLIKIHPMLRAIITENGKQKILQEVEYYKIMTSADSELIIRDIMSQQVLNLDK
                     WPIFDIRISKREDKADIIHISFDNIILDGWSMFFILEQWSNIYKYGKYEEAI"
BASE COUNT          352 a          234 c          109 g          464 t
ORIGIN      
        1 aatagcttct tcatatttcc catatttgta tatattagac cattgttcca gaatgaaaaa
       61 catactccat ccatccaata ttatattatc aaaactaata tgaattatat ccgctttatc
      121 ctcacgcttg ctaattctta tgtcaaatat aggccattta tccagattaa gcacctgttg
      181 tgacataatg tcacggataa tgagttctga atctgcacta gtcattattt tataatattc
      241 tacctcttgc agtatcttct gcttaccatt ttcagttata attgctcgta acatcggatg
      301 aatttttatt aaataattcc acgctttctc caacttattt acatctatat cacttgattc
      361 tatttcaaaa taacaatgag tagaaactcc tcctaaaatc atatccttgt ttcttccaac
      421 ataataagca tgttgaacat ccgtcaaatc aaactcttcc tctgtaatag tttcctctat
      481 cacgctaatt ttatccgcaa aacgctgctc agcaattcta tctttaatca cttgggcttg
      541 tgcttcaata gtaatatttt ccattacatc ttttatacta aaacttattt tgaatttttc
      601 ctctatttta gctgatagtt ttgttgcaat tagagaatct ccaccatttg aaaaaaagct
      661 agttctatac tttgtatcat atccaaatat ttctttccat atatccttta aagtttctat
      721 ttctctatca tctaaaatca tatcgaaaat attaccttgc aattttttgt ccttatatat
      781 ttcctctagt tttttcctat caactttccc atttttattt tgtggcatat ttttgagtaa
      841 tactatatca tccggcacca tatatatcgg aaccatattt ctcatcttcg ccttaatagt
      901 ctcaatatca acaaactgta ttcttttttc taatatatat acaatacttc ctccaactga
      961 tatttgctta caacaattaa gatttgcatc gtaaaaaata ctattccatt catcaacatt
     1021 aaaaatatta tcattatatc cggcaaaatt attaagaata cttgtagtta tatcttgaat
     1081 gcgtattcgt tctttaggct ctacaactat gagtttgcca ttattagtca acaagtttct
     1141 caactttttc attgtttcc
//
LOCUS       DARYXZ010000121         1103 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYXZ010000121 DARYXZ010000000
VERSION     DARYXZ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1103
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            7..399
                     /locus_tag="TV186_002040"
     CDS             7..399
                     /locus_tag="TV186_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1533379.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            474..875
                     /locus_tag="TV186_002041"
     CDS             474..875
                     /locus_tag="TV186_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1533380.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            872..>1103
                     /locus_tag="TV186_002042"
     CDS             872..>1103
                     /locus_tag="TV186_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1533381.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDS"
BASE COUNT          401 a          156 c          225 g          321 t
ORIGIN      
        1 atagacatga ataggttttt aaagatcagt ctgcttattg ttggtgttat tgtcattatg
       61 cttggcatgg aagtaaagca tagaatggat atatacgatc aaatcaagca ggaggagata
      121 aaaattgccc aaagtaaaga agcaattgtg atttatgaac aggagttaaa atggttggac
      181 ccaaatgcat tgacaaatga agggactatt aaatcctatt ctattgattt agactcaata
      241 actcttaatc caatgggagg cttttccatt gctttacata taaacaaaaa tccaaagtat
      301 aagtatcgaa taagtttaat gtggaataca ccaatgagag atttatgtgt gggaggatcc
      361 tctttgtcgc cagaattaca agaattgtta gataggtaat gattatgaca ggctatcaga
      421 aacaattgat tgcaccaaag aacaatataa ttttcatgaa aaggagcata gttatgaaaa
      481 cattgttaaa actcattgta tttattgttg gtactcttgt acttatgctt ggcatggagg
      541 taaagcatag aatggataca tacgatcaaa tcaaacaggt agagctcaaa aacgcgcata
      601 gtaaagaagt gattgaaatg tatgaacagg agctaatatc aatggatccc caggccctaa
      661 cagatgaagg acttatcaag tcctacacta tcgactcaga ttcactcttt attaatccga
      721 tgggaggctt ttccattcat ttaattatca atgatgatcc agatatttac ttgagagttg
      781 gccttggtag atatgatatg gaaagaaatt tggagattga tggtatctat cgctcagaaa
      841 agttagaaaa actactaaaa ggagtggaga gatgaaaaca ttgttaaaac ttattgtatt
      901 tattgttggt gcccttgtac ttattcttgg catggaggta aagcatagaa tggatatata
      961 cgatcaagtc aaacaggtag aactcaaaaa cgcgcatagt aaagaagcga tagacattta
     1021 tgaaaagaag ttaaaaagat tggatcctca ggccctaaca gatgaagggc ttatcaagtc
     1081 ttatactatt gactcagact caa
//
LOCUS       DARYXZ010000122         1087 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYXZ010000122 DARYXZ010000000
VERSION     DARYXZ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1087
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..559)
                     /locus_tag="TV186_002043"
     CDS             complement(<1..559)
                     /locus_tag="TV186_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1533382.1"
                     /translation="MEYIERPKYLNHIEKFVDKPIIKILTGMRRVGKSTILMMIKDEI
                     LKHVPDEQKIYINFESLEFMSINEASFLASYISEKSKNLSGKLYYFFDEIQLVNNWEK
                     VVNGLRVDQDCDIYITGSNSNLISGELATLLAGRYIEFEIQPFTFGEFLKIFSDSNLT
                     KEALFDKFIKLGGMPILKYFKLEEDS"
     gene            639..1037
                     /locus_tag="TV186_002044"
                     /pseudo
     CDS             639..1037
                     /locus_tag="TV186_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          386 a          184 c          141 g          376 t
ORIGIN      
        1 tgctatcttc ttctaactta aaatatttta aaatcggcat tccacctaat tttataaatt
       61 tatcaaaaag tgcttcttta gttagatttg aatcactaaa aatctttaaa aattccccaa
      121 aagtaaatgg ctgtatttca aattctatat atcttcctgc aagaagtgtg gcaagttcac
      181 cggaaatcaa atttgaattt gaaccggtaa tgtatatatc acaatcttga tctactctta
      241 acccattaac tactttttcc cagttattta ccaactgtat ttcatcaaag aaataatata
      301 atttaccact tagatttttt gacttttcac ttatataact tgccaaaaag ctcgcttcat
      361 ttatactcat aaactccaaa gattcaaaat tgatatatat cttttgctca tccggcacat
      421 gtttcaaaat ttcatcttta atcatcatca gaatggtaga ttttccaact cttcgcatcc
      481 cagttaagat tttaataata ggtttatcaa caaatttttc tatatggttt aaatacttgg
      541 gtcgttcaat atattccata tcattcacct ctctttagct ttgattatat tatacacgat
      601 aaaaatatat tttccaatat tgttttcgaa tataatcgaa atatatcata aaagcagccg
      661 atgaaaggca aaatttacag gataagatca aggctattga taaggaaatg caggagcttt
      721 ctgccactat ggagcaagtt cacactgtta aaaaatacag gcaatactac aaagaatata
      781 aggcaagtcc atctgacaag gcattttttg aagagtacaa agctcagatt accttatatg
      841 aaaatgccct ttcagagctt aaaaaatcat attccaagtt gccaaattct aagggtattt
      901 tagatagact tgataaattg caagaaaaaa agaataccct tatgcaagag tattcttcct
      961 caaaatctat tatggacgaa ctttacaaga tacgaaaaaa ttatggaatt tacatgggta
     1021 aggagatgga gagataattt tttctctcca tcatcattta ttaccaagtt gatggtttat
     1081 ggtttat
//
LOCUS       DARYXZ010000123         1030 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYXZ010000123 DARYXZ010000000
VERSION     DARYXZ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1030
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            135..1030
                     /locus_tag="TV186_002045"
                     /pseudo
     CDS             135..1030
                     /locus_tag="TV186_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          349 a          189 c          220 g          272 t
ORIGIN      
        1 ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt caaatctatg
       61 agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt attgcagaat
      121 ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt gtccaaaaag
      181 gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa gttctgattg
      241 atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct agtatgcttt
      301 caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa agaagaggga
      361 ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca gagttggagc
      421 gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa aagctgagag
      481 aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc aagaattaat
      541 cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt caacctatta
      601 ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg agctcattca
      661 aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc tggaactaag
      721 aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg tcatgggctt
      781 aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg ttggcaaaaa
      841 ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga agtgctatac
      901 cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg ttcttgacgg
      961 ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga agcaagtaca
     1021 aaccatgctt
//
LOCUS       DARYXZ010000124         1021 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYXZ010000124 DARYXZ010000000
VERSION     DARYXZ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1021
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            130..1021
                     /locus_tag="TV186_002046"
                     /pseudo
     CDS             130..1021
                     /locus_tag="TV186_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          361 a          169 c          224 g          267 t
ORIGIN      
        1 caatggggtg ctttttatat gaaattaagt tacgatgata aattaagaat atatgaacta
       61 agaaaaaatg ggatgtcttg ttcccgcatt ggtcaacagt atgatattca ggtttctaat
      121 ctcaaataca tggtaaagct tatggacaga tatggagttg agattgttag aaagggtaaa
      181 aataagtatt atcctccaga attaaaacaa gaaataattg ataaagttct tcttgaaggt
      241 cagtctcaac tgtctgtctc tcttgagtat gctctcccaa atgctggtat gcttcccaat
      301 tggatagcgc aatacaagaa aaacgggtat actattcttg agaaacaaag agggagacca
      361 acgaagatgg gccgtaaacc aaagaaaact tgggaagaaa tgacagagct agagcgcctt
      421 caggaagagc tagaatacct tagaacggag aatgcttatc taaaaaagtt gagggagctt
      481 cgtttacagg acgaagccag agaatgagaa aggcagaaac aattagagag atggtccaag
      541 aaggattccg attaaacctc ctacttgaga tcgctaagat ggctcgttca acctattatt
      601 atcaagtcaa gcaattggat aagtcagata aagatgaagc aatcaactct gaaatcaaag
      661 cgatttatga ggagcataag ggaaactatg gttaccgtcg cattcattta gaactcaaga
      721 atcgtgggtt tatcgtcaat cacaagaaag tgcaacgctt gatgaaagag atgagattag
      781 ctgctcgaat tcgtcgtaaa cgcaggtatt cctcttacaa aggcgagact ggtaagaagg
      841 ctgataatct gattcaacgc cagtttgaag ctgctaagcc atatgaaaaa tgttataccg
      901 atgtgacaga gtttgcttta ccaaacaacg atgaaaaact ttatttagcg cctgttcttg
      961 atggctacaa cagtgagatt attgatttca cactatctag gtctccagac ttaaaacagg
     1021 t
//
LOCUS       DARYXZ010000125         1006 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYXZ010000125 DARYXZ010000000
VERSION     DARYXZ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..158)
                     /locus_tag="TV186_002047"
     CDS             complement(<1..158)
                     /locus_tag="TV186_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1533383.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLLAKVEAKLRE
                     YAKDEVDI"
     gene            complement(167..>1006)
                     /locus_tag="TV186_002048"
     CDS             complement(167..>1006)
                     /locus_tag="TV186_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1533384.1"
                     /translation="AGGIDAKMSGSEIISAINLNTYGAVIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIKADQIIAGTLDASKARIINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLSNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNATPKNYTGS
                     ALYASIGITSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDIVFSDDFN
                     IDRGFKMRPSLMPKMVDLNKMYQAILALGRCWLHANNTAWTFNSDTTSAIIREYNSYI
                     NGL"
BASE COUNT          263 a          230 c          209 g          304 t
ORIGIN      
        1 ataatatcaa cctcgtcctt agcgtactct cttagcttag cctcgacttt ggcaagcagc
       61 ttagcgcggc cgcgattaac tctcatgtta gtaaccttaa ttttgtctag tacgctatag
      121 agcgtattta agtctttgtt ttgtactgtt aaatccatgt tgtctcctat aatccattaa
      181 tatatgagtt atactctctg atgattgcac tagtagtgtc tgagttaaag gtccacgctg
      241 tattattagc gtgtagccag cagcggccaa gagctaaaat ggcctgatac atcttattga
      301 gatcgaccat ttttggcatt aggctaggcc gcatcttaaa gccacgatcg atgttaaaat
      361 cgtcgctaaa gacaatatca tcaccgtaaa tttcggcctg atcgacaagc gctgtgtgct
      421 cgtaacctcg cgcataccta aaaaacctag caccgcaaaa acgaccgctc gacgcgctgt
      481 taatcccgtc acctgacgat gttatcccga tcgaggcgta aagcgcacta cctgtataat
      541 tttttggcgt ggcattgcta aaatgcacaa aggctgtgtg ggtaccgtct ttacgtacca
      601 aagcgttgtc tttgttatta aagttaatgg tagcgttgct gttaaagtca atcttagagt
      661 ttgacaagtc aatcatcatc gctccgttgc gagctctgat aactttgccc tcgagcaaac
      721 ttgtgatcgt atgctcgatt ttggccctga taaaattagc atctaagccg acaatgctgc
      781 tagcgtttag attaatgata cgagcctttg aggcatctaa agtacctgcg ataatctgat
      841 cagccttgat tttgatagcc tcggctatct tagtggtaaa agtgccattg accgttgtat
      901 tgccatcaag agcgatgtgt ttacctgcaa tgactgcgcc atacgtattg agattaatcg
      961 ctgagataat ctcgctgcca gacattttag catcaatccc accagc
//
LOCUS       DARYXZ010000126          958 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYXZ010000126 DARYXZ010000000
VERSION     DARYXZ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>958
                     /locus_tag="TV186_002049"
     CDS             <1..>958
                     /locus_tag="TV186_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1533385.1"
                     /translation="QDNQKVRLASNCLGTTRFNQVMIERGDKATDYVAPVVVEGSGES
                     TGVFKSLEEMLSGLQSINLELTDTKNSNLWSKIKLTTNGMLREYHRDHIKTEIVESAD
                     GIAKRIADDTGQKLALINETIKGIKREYQDADRQLSASYQAGIDGLKTQLANDKIGLQ
                     AEIKLSAQGLSQKYDDELRKLYAKITTTSSGTTEAYENKLEGLRAEFTRSNQGMRTEL
                     ESQISGLRSVQQSTAKQISQEIRDRTGAVSRVQQDLASYQRRLQDAEKNYSSLTQTVK
                     GLQSTVSDPSGKIQSRFTQLQNQIDQRVTRDDVMSIINLSGD"
BASE COUNT          308 a          207 c          236 g          207 t
ORIGIN      
        1 gtcaagacaa tcaaaaagtc agattagcca gcaactgtct aggaacaact cgctttaatc
       61 aggttatgat tgagagaggc gacaaagcga ctgactatgt tgcgcctgtt gtcgttgagg
      121 gcagcggtga gtcgacaggt gtgtttaaaa gtcttgagga gatgcttagt ggtctacagt
      181 ctattaattt agagctgaca gataccaaaa actccaatct ttggtcaaaa atcaagctca
      241 cgacaaacgg tatgttacgc gagtatcatc gtgatcatat taaaacagag attgttgaga
      301 gcgcagatgg tattgccaag cggattgccg atgacactgg ccaaaagctg gcactaatca
      361 atgagaccat caaaggtatc aagcgtgagt accaagacgc agatagacag ctatccgcga
      421 gctaccaagc gggcattgat ggcctaaaaa ctcaactggc caatgacaaa atcggtctac
      481 aagctgagat taagctgtca gctcaaggct tgtcgcaaaa gtacgacgat gagctgcgca
      541 agctgtatgc taagattacc accacctcat caggcacgac cgaagcgtac gaaaacaagc
      601 ttgagggctt gcgtgctgag tttacccgta gcaaccaagg catgcgcact gagttagagt
      661 cgcagattag cgggttaagg tctgtgcagc agtcaactgc aaaacaaatc tcgcaggaga
      721 ttagagacag gacaggtgct gttagtcgtg tgcaacagga cttagccagc tatcaaagac
      781 gcttgcagga cgccgaaaaa aattacagca gtttaaccca gacggttaaa ggtctacaat
      841 caactgttag cgatccgtca ggtaaaatcc agtcgaggtt tacacaacta caaaatcaaa
      901 tcgaccaacg tgtgacaaga gatgacgtta tgtcaatcat caacctatcc ggagatag
//
LOCUS       DARYXZ010000127          920 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYXZ010000127 DARYXZ010000000
VERSION     DARYXZ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..920
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>920
                     /locus_tag="TV186_002050"
     CDS             <1..>920
                     /locus_tag="TV186_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1533386.1"
                     /translation="RLDLFNEIIKATGLEFSVSGKVVRLLKNIGTDLSTVVRKNFNMN
                     DLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPLAKEYGRLEGAPLTDERFT
                     VADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVAGDYIMAINETLGFQERIR
                     IVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSRINQIDADIASAIEVATQA
                     LVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTRMYFWNGAEWEEPEVVNDP
                     EQWREDLEKQISEAIEKAKKAQEEINQRTD"
BASE COUNT          326 a          156 c          218 g          220 t
ORIGIN      
        1 aggttagatt tattcaatga gattattaaa gcgaccggac ttgagttttc agtcagcggg
       61 aaagttgttc ggctattaaa aaacataggt actgatctgt caacagtggt acgaaaaaat
      121 ttcaacatga atgatcttac cattgaaaaa aatattgata gctttattac ctatcagaaa
      181 ggctttggtg catggaccga cccagaggac cactctaagg ggagacttga ggcggaatac
      241 gaaagccctc ttgccaagga gtacggtcga cttgaagggg cgcctctgac ggatgagcgc
      301 ttcacggtgg cagataatct aaaagaagct ttaaaaagta atgttgaaaa ttcttataag
      361 atatcagtaa aaattgatat ggaagattta acgagagctg gttatagatg tgagaggccg
      421 gttgctggtg actacattat ggcgataaat gagactttag gttttcaaga gcgtatacgg
      481 atagtttctt ttacaagcta ctacgacgca actggagctt tagtaaaaca tgaagtcact
      541 tgtaatgata tcggatctgt gaaaaaacaa agcgtaggaa gtctgtctat aaacagtaga
      601 atcaatcaga tagatgcaga tattgcttct gcaattgaag tagcaacaca agcactagtg
      661 tctgctgacg ggaaaaatac tgtttacggt ggcacagaaa tgcccaaaga tgaaccaaaa
      721 ggaaccttaa aaaaaggaga catactattc ctaaaagttg gcgatactac tagaatgtat
      781 ttctggaatg gtgctgagtg ggaagaaccc gaggttgtga acgacccaga acaatggcgt
      841 gaagacctcg aaaaacaaat ctctgaggca atcgaaaaag ccaaaaaagc gcaagaagaa
      901 atcaaccagc gcaccgacaa
//
LOCUS       DARYXZ010000128          908 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYXZ010000128 DARYXZ010000000
VERSION     DARYXZ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(7..492)
                     /locus_tag="TV186_002051"
     CDS             complement(7..492)
                     /locus_tag="TV186_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL1533387.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(581..654)
                     /locus_tag="TV186_002052"
     tRNA            complement(581..654)
                     /locus_tag="TV186_002052"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(618..620),aa:Arg,seq:acg)
BASE COUNT          274 a          261 c          137 g          236 t
ORIGIN      
        1 ccccttttat ttctcaccag taaagtcctg aaagtaaggt cctatcttgc gaagcaaggc
       61 ccgtctcccc tcaaaccgct ctcccctgat caaagcccga aactgcgaca gctcaccctc
      121 tgtcaatcgc tcctcaacct ccttcacaat caactgataa gccacataat catctactcc
      181 caaaccacct gctggtatcg catggcctac cgacccaatc tcctcataag ccatcttatg
      241 aaaccgacgc ttctgactct cctgctgccg caacacgtcc ttcaaataag aggaaaactt
      301 ggtcttaaaa taacgatata gcttctcctc atcctctatc aattctggat aagtgaccaa
      361 taaccgatac aagatcaacc gcccctcctg taaccaatca tctagctccc acagctgaat
      421 ataataatgc tgtcttagct tcataataat aggcttgatc ttatcaaaca acctcactaa
      481 atcatcagtc attatacttt ctccttttca tgcttagtag ccttattata aggagacaaa
      541 caaaaaaaca acaggacaga aatgtcctgt tgccttgcta tgcaccctag aggagtcgaa
      601 cctctaaccg cctgattcgt agtcaggtac tctatccagt tgagctaagg gtgcttttct
      661 taactattac tatcctacca tactatcccc taaaaagcaa ggctctatac catctggaat
      721 aggtaagtcc actgtggaaa tcatagagct ttttgagtac acaaaaaaga gagcaccaaa
      781 ctgatcctct ctaaatgtcc gttgttagtc aacccactat agttgacata gagccaaact
      841 ccgccagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg
      901 agctatgg
//
LOCUS       DARYXZ010000129          886 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYXZ010000129 DARYXZ010000000
VERSION     DARYXZ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..886
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..805
                     /locus_tag="TV186_002053"
     CDS             <1..805
                     /locus_tag="TV186_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1533388.1"
                     /translation="KLETDSKIAKLVSSKADKSAVYLKAESKIELDKKLSLTGGVMTG
                     QLKFKPAATVAYSSSTGGAVNIDLSSSRGAGVVVYSNNDTSDGPLMSLRTGKETFNQS
                     ALFVDYKGTTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHE
                     NPNVKASYDKNAAALSIDIVKKANGVGTAAQGIYINSTSGTTGKMLRIRNLNDDKFYV
                     KPDGGFYAKETSQIDGNLKLKDPIANDHAATKAYVDGEIKKIKALLTAK"
BASE COUNT          307 a          172 c          199 g          208 t
ORIGIN      
        1 aaaactagaa actgatagta aaatcgccaa attagtatca agcaaagcag ataaaagcgc
       61 tgtttactta aaagcagagt caaaaataga gctagacaaa aaattgagtt tgacaggtgg
      121 cgttatgaca ggccaactaa aatttaagcc agccgccact gttgcttatt cctcgtcaac
      181 gggtggagcg gtcaatattg acttgtcgtc tagcagaggt gctggtgttg ttgtctattc
      241 taacaatgat accagtgatg ggccgttaat gagcttgcgg acgggtaaag agaccttcaa
      301 tcaatcggcg ctttttgtcg attataaggg aacaacaaat gccgttaata ttgcgatgcg
      361 tcagccaacc acccccaatt tttcatcggc gcttaatatt actagcggca atgaaaatgg
      421 tagtgcgatg caaattagag gcgttgaaaa agcattggga acgctcaaaa tcacgcacga
      481 aaacccaaac gttaaggcaa gttacgataa aaacgctgca gcgttatcta ttgatattgt
      541 caaaaaggca aacggtgtag gaacagccgc tcagggaatc tacattaact caacctcagg
      601 cacaactggt aaaatgctca gaatcagaaa ccttaatgat gataagttct acgtcaagcc
      661 tgacggtggt ttttatgcca aggaaacttc gcagattgat ggcaacctga aactcaagga
      721 tcccatagcg aatgatcatg cggcaaccaa agcttatgtt gatggtgaaa tcaaaaaaat
      781 aaaagcactc ttaacggcta agtaaatgta aaaaggagga gatatgagca gagacccaac
      841 attaacatta gacgagtcaa atttaacgat cggctcagat ggacgt
//
LOCUS       DARYXZ010000130          880 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYXZ010000130 DARYXZ010000000
VERSION     DARYXZ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..808
                     /locus_tag="TV186_002054"
     CDS             <1..808
                     /locus_tag="TV186_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1533389.1"
                     /translation="KKETDSKITKLASSKADKSAVYLKAESKIELDKKLSLTGGVMTG
                     QLRLKPNSGIKHSSSVGGAINIDMSKSTGAAMVMYTNKDTTDGPLMILRSDKDTFDQS
                     AQFVDYSGKTNAVNIVMRQPSAPNFSSALNITSANEGGSAMQIRGIEKALGTLKITHE
                     NPSLGADYDENAAALSIDIVKKANGAGTAAQGIYINSTSGTTGKLLRIRNENKDKFYV
                     NPDGGFWSCANSTVAGNLTVNDPTSEKHAATKKYVDEKIAELKKLIQKTD"
BASE COUNT          329 a          159 c          185 g          207 t
ORIGIN      
        1 aaaaaaagaa actgatagta aaatcaccaa attagcatca agcaaagcag ataaaagcgc
       61 tgtttactta aaagcagagt caaaaataga gctagacaaa aaattgagtt tgacaggtgg
      121 cgttatgaca ggccaactac ggcttaaacc taatagtggt attaagcact catcttccgt
      181 aggaggagcg attaacattg atatgtctaa atcaacaggt gctgctatgg tgatgtatac
      241 aaataaagat actactgatg gaccattgat gattttacgc tctgacaaag atacgtttga
      301 tcagtcagct caatttgtgg attacagcgg taagactaat gctgtaaata ttgtaatgcg
      361 ccagccaagc gcacctaatt tttcctcggc acttaatata accagtgcca acgaaggcgg
      421 tagtgcgatg caaattagag gcatcgaaaa agcattggga acgctcaaaa ttactcatga
      481 gaacccaagt cttggagcgg attatgatga aaacgctgca gcgttatcta ttgatattgt
      541 caaaaaggca aacggtgcag gaacagccgc tcagggaatc tacattaact caacctcagg
      601 cacaacaggg aagttgctta gaattagaaa cgaaaataaa gacaaatttt atgtaaatcc
      661 agatggtggc ttttggtcat gtgcaaattc gactgtagct ggtaatctaa cagttaacga
      721 tccaacatct gaaaaacatg ctgcgactaa aaaatacgta gacgaaaaaa ttgctgagtt
      781 aaaaaaactt atacaaaaaa cagattaagg aggataaatg agtagagatc caacactaac
      841 attagacgag tcaaaactcg tcataggacc agacggccgc
//
LOCUS       DARYXZ010000131          848 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYXZ010000131 DARYXZ010000000
VERSION     DARYXZ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(109..624)
                     /locus_tag="TV186_002055"
     CDS             complement(109..624)
                     /locus_tag="TV186_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533390.1"
                     /translation="MKSKKLVFGQIDLNMCRDFDLVQALDYDFKEKKLYNKGRGFAIV
                     LVSIQNLTFAIPLRSNIPKKYQLKYKLRDSKKYGCVEGLDIGKALVVEDPKYILNRTF
                     KLREQVDYFKIVDNDILIVNKLIKAIIDYNQAVANSDQHKLTDPKRFKFSTFPNYTDR
                     LKSITDADYLR"
BASE COUNT          263 a          150 c          137 g          298 t
ORIGIN      
        1 aatacatgtg tgtgaaacac aaaaaaccgc ccagaaataa tctgagcggt tgatttttat
       61 tttggctaat tcttactatg gtaattggtt catgattgtg cgagggtgtc aacgaagata
      121 atcggcatcg gtaatgcttt ttaatctgtc ggtatagttt gggaatgtag agaatttgaa
      181 acgtttagga tctgttaatt tatgttgatc actattagct acagcttgat tataatctat
      241 gatagccttt atcaacttgt taacaataag tatatcatta tcaacaatct taaaataatc
      301 aacctgctct cgtaatttga acgttctgtt taaaatatat tttggatctt caaccactag
      361 agctttgcca atatcaagcc cctctacgca tccgtatttt ttagagtctc ttaatttata
      421 ttttagttga tattttttag gaatattact tctcaaaggg attgcaaaag ttagattttg
      481 gatacttacc aacacaatgg caaaacctcg gcctttgtta tatagcttct tctctttaaa
      541 atcatagtct aaagcttgta ccaaatcgaa atctcgacac atgtttaaat caatctgacc
      601 gaatactaat tttttactct tcattatttg ccttctaaaa ataaaaaatc ctaccaactg
      661 ggtattggta ggacgcattg ccaacgggat acttctgtta acgagcgcgt ccctccgccc
      721 cctcattgcc aaaatggcga gagtttaacg acatggaaag gtcggaacat agagataatg
      781 cttttactat ttatgttcat ttacattatt acataatatg ttgcattcgt caaatataga
      841 atctttaa
//
LOCUS       DARYXZ010000132          836 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYXZ010000132 DARYXZ010000000
VERSION     DARYXZ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..221)
                     /locus_tag="TV186_002056"
     CDS             complement(<1..221)
                     /locus_tag="TV186_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533391.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRG"
     gene            complement(241..633)
                     /locus_tag="TV186_002057"
     CDS             complement(241..633)
                     /locus_tag="TV186_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533392.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            complement(630..>836)
                     /locus_tag="TV186_002058"
     CDS             complement(630..>836)
                     /locus_tag="TV186_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533393.1"
                     /translation="LSWAELEEAYAQAGVTYDSLVGQTKRHFDDKVTQARGLATKFKT
                     VKEQLEEGVERTAAIDQKLGCDFS"
BASE COUNT          165 a          228 c          180 g          263 t
ORIGIN      
        1 tgccctctaa tgctgctatc tagctgattg acaatggtct gaatatgatc tgcggtgtct
       61 gtggcaatcc gagatacctc actgtcatag cgcctttgaa gggcatgaag gcgacctaag
      121 gtcaagggag cacatatgga ctgaactaat ctcctatcca gctctttctt taaagtcctg
      181 atcggctctt gtccggttaa gatcatctct atagcaatca tctttcttat ctccttttcc
      241 ttaaccttca cgccactgac gcctcagcgc tgtgatgtcc ttttctatcg cctgtcgctg
      301 gctgcgatag tgatggtcaa ttgcttcctc ctgctgcgac atcttgcgac cttgctcatg
      361 atagcactgc tctgttcggt gctggtagtc atcaatcagc ctcgttagaa cggtatattg
      421 gtctgttatc agactagcat cataatgtct gaggtagctg ctaacggcct gatagctaga
      481 ggcatagagc tgctgtagct ggttatagtt gcctcttaac tcgtcatggg ctgctgccat
      541 ttggagccgc tcttgatgat agtgctcctg ctgctcctct agctcctctt ccttttgacg
      601 gatagcagtt ctgatctttt ctaatgctgt catgaaaagt cgcatcctag cttttgatca
      661 atagcagctg ttctctcaac cccctcctct agctgctcct ttacggtctt gaactttgtg
      721 gccagtcctc tagcttgagt aaccttgtca tcaaaatgcc tcttggtctg acccacaagg
      781 ctgtcatagg tcactcctgc ctgggcataa gcctcctcta gctccgccca gctcaa
//
LOCUS       DARYXZ010000133          724 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYXZ010000133 DARYXZ010000000
VERSION     DARYXZ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..724
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>724
                     /locus_tag="TV186_002059"
     CDS             <1..>724
                     /locus_tag="TV186_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEL1533394.1"
                     /translation="IIHFKIFNKRIDYVNTGELFSEIDQKIVRFKGFEDINDRDLRVG
                     TFYYPKNEERKHLILLVCGYEESYLDFKSEIFFWLKNGYTVFCYDVRGTGRSQGRKVG
                     GFTQFLKDCLLSIEYIEKNETFKKVSLVGHSMGGFAVATSLQFKTNIIDNSVIISGFD
                     YPSEFVRKSVTNISFIFTWPIEISIKLIEFLKFGNLSFLGSVSSINIFNKPVLIIQSS
                     DDKIVKINNSIYNKKKMITNKNV"
BASE COUNT          277 a           70 c          127 g          250 t
ORIGIN      
        1 ctattataca ttttaagata tttaacaaaa gaatagacta tgtaaataca ggtgaattat
       61 tttctgaaat agatcaaaaa atagttagat ttaagggatt tgaagatatt aatgatcgtg
      121 atttgagagt agggacattt tattatccca agaatgaaga aaggaaacat ttgatattac
      181 tagtttgtgg atatgaagaa tcctatttag actttaaatc cgagatattt ttttggctga
      241 aaaatggata tactgtgttt tgctatgatg ttagaggaac tggaagaagt cagggaagaa
      301 aagttggagg ttttactcag tttttgaagg attgcttatt gtccattgaa tacattgaaa
      361 aaaatgaaac ttttaaaaag gtatctttag tggggcatag tatgggaggt tttgcagtag
      421 cgacttcgtt acaattcaaa accaatataa tagataacag tgtaatcatt tcaggatttg
      481 attatccatc tgaatttgta agaaaaagtg taacaaatat ttcgtttatt tttacatggc
      541 caatagaaat atccataaaa cttatagaat ttttgaaatt tgggaacctg tcttttttgg
      601 gatcagttag tagcattaat atatttaata aacctgtact aataattcaa tctagtgatg
      661 ataaaattgt aaaaattaac aactctattt ataacaaaaa aaaaatgatt acaaataaaa
      721 atgt
//
LOCUS       DARYXZ010000134          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYXZ010000134 DARYXZ010000000
VERSION     DARYXZ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>672
                     /locus_tag="TV186_002060"
     CDS             <1..>672
                     /locus_tag="TV186_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1533395.1"
                     /translation="AAGYATASDYAELLIQLIEENNLQKWDKEALKTNKEVTMTTANE
                     IVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLWGNAIDLLNSAAAQGLE
                     VIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQVGG
                     PARFNTRDFTGVVGWIRLPVDHTNQTVDTAPQTSDTIVETSKTGTFTLDAAEINVRRW
                     PNLTS"
BASE COUNT          193 a          135 c          175 g          169 t
ORIGIN      
        1 agcagccggt tatgccactg caagtgatta tgcggagctg cttatccagt tgattgagga
       61 aaacaacttg caaaaatggg ataaggaagc cttaaaaact aataaggagg taacgatgac
      121 aaccgcaaat gagattgtac aatactgtgt tgaccttgcc aactcaggta tgggagttga
      181 taaagatggc tgttttggga cgcagtgtgc ggacttgcca tgttttatcg tcaaaaactg
      241 gttcgggatt gacttatggg ggaatgcgat tgacctgtta aacagtgcag cagcgcaagg
      301 tctagaggtt atctataacg cacctggagt taatccaaaa gctagtgact tatttgtcat
      361 ggaggtagct ggcagtcctt atggacacac aggagctgtt attgaggaca gtgatggcta
      421 taccattaaa actgttgagc aaaacattga cggcaactgg gacagtttac aagtaggtgg
      481 ccctgctcgc tttaatactc gtgactttac tggcgttgtc ggctggatta ggttacctgt
      541 tgaccatact aaccagacag tagatacagc accgcaaacg tctgacacca tcgtggagac
      601 gtcaaaaacg ggtactttta cacttgacgc cgcagagatc aacgtccgcc gctggccgaa
      661 tttaaccagt ga
//
LOCUS       DARYXZ010000135          671 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYXZ010000135 DARYXZ010000000
VERSION     DARYXZ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            29..>671
                     /locus_tag="TV186_002061"
     CDS             29..>671
                     /locus_tag="TV186_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEL1533396.1"
                     /translation="MSCPTFGGQYKVSQTLGSDFDLPYYIYSKIKRNKTEKVISPLKI
                     GLKITNACYFRCPYCFVSKEEDYLLFDHLKIIIDKLPQLPFEVYLTGGEATLHPEFPK
                     IVDYLVDLGILVKLHTTGVITEKSRNYIISNLEKFSSIQISIDSIKNFDKLRPSHIVI
                     NPLEQICSFVQKCLDRDYKKLLVNIVISSLNIHELDEVIDFCFKQGLLRIQLSS"
BASE COUNT          233 a           92 c          102 g          244 t
ORIGIN      
        1 caatacagaa ctaaatcctt tcactaatat gtcgtgtcca acttttgggg gtcagtacaa
       61 agtatcacaa actctgggga gtgattttga tttaccttat tatatatatt ccaaaataaa
      121 aagaaataag acggaaaaag ttatatctcc tcttaaaatt ggtttgaaaa ttaccaatgc
      181 atgctatttt agatgtccgt actgttttgt atcaaaagaa gaagattacc tcttgtttga
      241 tcatttgaaa ataataatag ataaactacc tcaacttccg tttgaagttt atctaactgg
      301 tggtgaagct actttacatc ctgagtttcc taaaattgtg gattatcttg ttgatctagg
      361 aattcttgta aaacttcata caactggggt aattactgaa aaaagtagaa attatattat
      421 ttctaattta gaaaaatttt cttcaataca aataagcatt gattctatca agaattttga
      481 taaacttaga ccaagtcata ttgttatcaa tcctttggaa caaatatgtt cttttgtgca
      541 gaaatgttta gatagagact ataaaaaatt gttagtgaat attgttatta gctcgttaaa
      601 tatccatgag cttgatgagg tcatagattt ttgttttaaa caaggattgt tacgtatcca
      661 attatcttct a
//
LOCUS       DARYXZ010000136          630 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYXZ010000136 DARYXZ010000000
VERSION     DARYXZ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>630
                     /locus_tag="TV186_002062"
     CDS             <1..>630
                     /locus_tag="TV186_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="equibactin biosynthetic protein"
                     /protein_id="HEL1533397.1"
                     /translation="LSINIGKTEVIIKAFNEMGRKNLDTDMRMLFSMTVGYASGRLTL
                     SSPLGPVLWEQSPNVPKIDLIPRFLDGNDNEGCSKPWLSILYEGDTYYKSYVYRNIWV
                     EAIMDDLKEFVFEDKSKKQSNSMKIQHQLETSILWQKIMNSLGYPKQKSLCRNKYIDP
                     DKFKRNEVSCYSIRESVDELNTVCRDTMFYHLSKHIPRQGISMLSLVEAL"
BASE COUNT          237 a           67 c          122 g          204 t
ORIGIN      
        1 ttatctataa atattggtaa aacagaggtt attataaagg catttaatga aatgggtagg
       61 aaaaatttag atacggatat gcgtatgctt ttttctatga ctgtgggata tgcgtctggt
      121 aggctaactt tatcaagtcc tcttggacca gttttatggg aacaatcacc taatgtacct
      181 aaaatagatc ttataccaag atttttagac ggcaatgata atgaaggatg tagtaaacct
      241 tggttatcaa ttctttatga gggagataca tattataaat catatgtata tagaaatatt
      301 tgggttgaag caataatgga cgatttgaaa gagttcgttt ttgaggacaa aagtaaaaaa
      361 caaagtaata gtatgaaaat tcaacaccaa ttggaaactt ctatattatg gcaaaaaatt
      421 atgaatagtt tagggtatcc taaacaaaaa tcattatgta ggaataaata tattgatcct
      481 gataaattta agagaaatga agtgtcatgt tacagcataa gagaatctgt agatgagttg
      541 aatacagttt gtagagatac aatgttttat catttgagta aacatatacc tagacaaggg
      601 atatcaatgt tatcattagt ggaagctttg
//
LOCUS       DARYXZ010000137          620 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYXZ010000137 DARYXZ010000000
VERSION     DARYXZ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..620
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(396..>620)
                     /locus_tag="TV186_002063"
     CDS             complement(396..>620)
                     /locus_tag="TV186_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1533398.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
BASE COUNT          175 a           99 c          133 g          213 t
ORIGIN      
        1 aaattaaaaa acaagactgt ttttgaaaac atttttatga tataataaag atattaacat
       61 tagaaaatga tatttgatga tctagaaata gtatcataac tatcttgtta aagaggttga
      121 agaaattagc gcatagaaaa aacgtatcag ttacgattat agtctagttt gtctttatga
      181 aatatagata acactgtaca atccttttct tttattgtac gactttatac aaagaaaagc
      241 ccttggaaat tattttctaa ggactttttt caatttgaga ggctggtgat agcctctttt
      301 tgaacttagg tcatcttctt agggcaatgc tgcctgaaga gatgagaaaa gctgttacta
      361 gctcattgcc taaggggaaa ggtgcaatgg ctggtttagt ttttcttgcc ttttaatgtt
      421 agcatgccgg cgctagcgat aacaccaagg gctgcaaggg tgaagaatgg gtgatttgtc
      481 tcccctgtag ctggtagtgt gcccttttga gctgctggcg ccatagcttt tgctgttgat
      541 ttagaatctg ctttaggtgc tgatggctta gcatcttttc catggtgacc cttatgtcca
      601 tgctcgcctt ggccttggat
//
LOCUS       DARYXZ010000138          619 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYXZ010000138 DARYXZ010000000
VERSION     DARYXZ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            186..>619
                     /locus_tag="TV186_002064"
     CDS             186..>619
                     /locus_tag="TV186_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1533399.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKG"
BASE COUNT          245 a          110 c          149 g          115 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 aacgaaacca aagattgaaa ttgatagata gctattccca ctctaatagt ggacatgtta
      121 gaatttcctt tgggaaagga agttacagga aactaagact gtttctacca caaaaggaga
      181 gaaagatgag atacacatta aacaaaaaca agcgtgctcg taactacggg ctatgctcag
      241 cagctatcgc tctagcagca gtagccagcc taggaacagc tggcagcgct aaagctgagg
      301 aagcaaaaac attagaccaa ctacctaatc cagaagagca aattctatat aattattggg
      361 acacaaatga tcagaaagca agagaatatc ttggagacct atacggtttc ctaaaatctt
      421 atttaggaga gttggaaaaa aaagctaaag agcctggacc tgctggacct aaaggtgaaa
      481 aaggcgaaaa aggcgaaaaa ggcgagaccg gtccgatggg gcctcaaggc ctaaagggtg
      541 aggacggaaa agacggcgca cctggagaaa aaggagaaaa aggtgatccg ggtatccaag
      601 gccctaaggg ggaaaaggg
//
LOCUS       DARYXZ010000139          575 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYXZ010000139 DARYXZ010000000
VERSION     DARYXZ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>575)
                     /locus_tag="TV186_002065"
     CDS             complement(<1..>575)
                     /locus_tag="TV186_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1533400.1"
                     /translation="AGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFG
                     AKLGEFIKLKADQIIGGTIDAAKIRVINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLNSAKMDFNSNATINFNNKDNALVRKDGTHTAFVHFSNATPKNYTGS
                     ALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT          159 a          148 c          110 g          158 t
ORIGIN      
        1 gcatacctaa aaaacctagc accgcaaaaa cgaccgctcg acgcgctgtt aatcccgtca
       61 cctgacgagg ttatcccgat cgaggcgtaa agcgcactac ctgtataatt ttttggcgtg
      121 gcattgctaa aatgcacaaa ggctgtgtgg gtaccgtctt tacgtacaag cgcattgtcc
      181 ttgttgttaa agttaatggt agcattgcta ttaaaatcca ttttagccga gtttaaatca
      241 atcatcatcg ctccgttgcg agctctgata actttaccct caagcaaact tgtaatcgta
      301 tgttcaattt tagccctgat aaagttagca tctaagccga caatgctgct agcgttaaga
      361 ttgatcactc taatcttagc agcgtcaatc gtaccaccaa tgatttgatc agctttgagc
      421 ttaataaact caccgagctt agccccaaat gccccattga cggtcgtatt accgtccaga
      481 gcaatacgct cgccagagat ccgcacgcca tagccattaa gatttatcgc tgagataatc
      541 tctttagcgc tcatcttagc gtcaatacca ccggc
//
LOCUS       DARYXZ010000140          538 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYXZ010000140 DARYXZ010000000
VERSION     DARYXZ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..538
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..379
                     /locus_tag="TV186_002066"
     CDS             <1..379
                     /locus_tag="TV186_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533401.1"
                     /translation="GFRRGETYTISFSQTCELLKKVAITLTQANNKGVKLVLTPTKAK
                     MEAQTFNLSKDKEVISVYPLSYRAALTGDWYKSKQVDLNAAEVQNLALEMAYRDVVDS
                     NNASLVLDWSENPDVIFDGNGGS"
     gene            379..>538
                     /locus_tag="TV186_002067"
     CDS             379..>538
                     /locus_tag="TV186_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1533402.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLI"
BASE COUNT          171 a           90 c          133 g          144 t
ORIGIN      
        1 tggttttaga cgcggcgaga catacacgat tagctttagc cagacctgtg agttgctcaa
       61 aaaagtggct atcacgctga cgcaagctaa taataaggga gttaaactgg tactgacacc
      121 taccaaagct aagatggagg cgcagacctt taatctaagt aaagataagg aggtcatcag
      181 cgtctatcct ttgagctaca gagccgcttt aactggtgac tggtataaat ctaagcaagt
      241 tgacttaaat gcggcagagg tccaaaattt ggctctggag atggcttata gagacgtagt
      301 tgatagcaat aatgctagtt tagttttgga ttggtcagaa aatccagatg ttatttttga
      361 tggaaatgga ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg
      421 acaaaaaacg agtgggagtc tagtgacatc attttgccac aaggccagct cgtctatgag
      481 tctgacacag gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatct
//
LOCUS       DARYXZ010000141          451 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYXZ010000141 DARYXZ010000000
VERSION     DARYXZ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(6..79)
                     /locus_tag="TV186_002068"
     tRNA            complement(6..79)
                     /locus_tag="TV186_002068"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(43..45),aa:Ile,seq:cat)
     gene            complement(100..173)
                     /locus_tag="TV186_002069"
     tRNA            complement(100..173)
                     /locus_tag="TV186_002069"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(137..139),aa:Met,seq:cat)
     gene            complement(184..257)
                     /locus_tag="TV186_002070"
     tRNA            complement(184..257)
                     /locus_tag="TV186_002070"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(221..223),aa:Pro,seq:tgg)
     gene            complement(264..337)
                     /locus_tag="TV186_002071"
     tRNA            complement(264..337)
                     /locus_tag="TV186_002071"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(301..303),aa:Arg,seq:acg)
     gene            complement(352..436)
                     /locus_tag="TV186_002072"
     tRNA            complement(352..436)
                     /locus_tag="TV186_002072"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(400..402),aa:Leu,seq:taa)
BASE COUNT          121 a          135 c          103 g           92 t
ORIGIN      
        1 cattatggac cttgtaggac tcgaacctac gaccgctcgg ttatgagccg agtgctctaa
       61 ccagttgagc taaaggtcca aaacaatcca aaaacaaaat agcggcgaag gggatcgaac
      121 ccccgacctc ccgggtatga accggacgct ctagccagct gagctacacc gccatcaaac
      181 taatcgggaa gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca
      241 agctgagcta cttcccgtaa ctatgcaccc tagaggagtc gaacctctaa ccgcctgatt
      301 cgtagtcagg tactctatcc agttgagcta agggtgcttt tccttatgct atgccgagga
      361 ccggaatcga accggtacga tgttaaccat cgcaggattt taagtcctgt gcgtctgcca
      421 gttccgccac cccggctccc caaaagcgaa c
//
LOCUS       DARYXZ010000142          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.145, whole genome shotgun sequence.
ACCESSION   DARYXZ010000142 DARYXZ010000000
VERSION     DARYXZ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.145"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(68..139)
                     /locus_tag="TV186_002073"
     tRNA            complement(68..139)
                     /locus_tag="TV186_002073"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Arg,seq:ccg)
BASE COUNT          144 a           82 c           64 g          147 t
ORIGIN      
        1 attggtagat tttctgtcta acttttgggg tgcgggtcat ttaataggct tttttatatc
       61 gtttctatcc accttgaggg aatcgaaccc ccatctcaag aaccggaatc ttgcgtgata
      121 tccattacac taaaggtggc acctttaacc ataccactac agtatagcat aaaagtggat
      181 attttaaaat ccttttttct aaaaagatca caccatacac atgacgaaaa tgcatgtcat
      241 tattttctag tcatatgcat tttatcacta tatttttaat attttgacat catcagtggt
      301 tcaaatacag tttagttata ccataaatgt tcttgaaaaa acacattgat tacgaaaatg
      361 ctaccagaaa atgtcagttt ctccatgcat tggtatgcta aaaaaatact ataaaaagct
      421 gagcaattac ccagctt
//
LOCUS       DARYXZ010000143          417 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYXZ010000143 DARYXZ010000000
VERSION     DARYXZ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>417)
                     /gene="glmU"
                     /locus_tag="TV186_002074"
     CDS             complement(<1..>417)
                     /gene="glmU"
                     /locus_tag="TV186_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1533403.1"
                     /translation="SRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHIG
                     NFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAFI
                     GSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGR"
BASE COUNT          103 a          133 c           81 g          100 t
ORIGIN      
        1 cgccctatag ccacactgtc tgccggcact gactgggcta tcgtagaccc tgcggctgtt
       61 aaagcattct ccccaacctc tactggagct atcaaagtcg aatgactccc aataaaagcg
      121 tgatcgccaa tcactgtctg gtatttccgt tgaccatcat aattaaccgt aatgcttcct
      181 gcaccaatat taacctctga gccaatctcg gcattcccca ggtaagtcaa atgccctgcc
      241 ttggtattgg cccctagatg agacccctta acctctacaa agttcccaat atgaacgctc
      301 tcatcgagct gggagtctgg gcgaatgtgc gcatagggcc ctactgtcac accatctgct
      361 aggactgaat cctcaatcac tgactggctc accactacgc cctcaccaag cctcgaa
//
LOCUS       DARYXZ010000144          388 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.147, whole genome shotgun sequence.
ACCESSION   DARYXZ010000144 DARYXZ010000000
VERSION     DARYXZ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.147"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(55..127)
                     /locus_tag="TV186_002075"
     tRNA            complement(55..127)
                     /locus_tag="TV186_002075"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92..94),aa:Thr,seq:tgt)
     gene            complement(135..216)
                     /locus_tag="TV186_002076"
     tRNA            complement(135..216)
                     /locus_tag="TV186_002076"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Leu,seq:tag)
     gene            complement(222..294)
                     /locus_tag="TV186_002077"
     tRNA            complement(222..294)
                     /locus_tag="TV186_002077"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(259..261),aa:Lys,seq:ttt)
     gene            complement(298..370)
                     /locus_tag="TV186_002078"
     tRNA            complement(298..370)
                     /locus_tag="TV186_002078"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(335..337),aa:Asp,seq:gtc)
BASE COUNT           98 a          119 c           85 g           86 t
ORIGIN      
        1 cccaccttgg caaggtggtg ttctaccact gaactacgtt cgcaactcta tcaatgccgg
       61 ctacatgact tgaacacgcg accctctgat tacaaatcag atgctctacc aactgagcta
      121 agccggccta tctatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      181 taaatctggt gcgtctgcca attccgccaa acccgccttt atgacccgta ctgggctcga
      241 accagtgacc ctttgattaa aagtcaaatg ctctaccaac tgagctaacg agtcctacgg
      301 tcccgacggg aatcgaaccc gcgatcttcg ccgtgacagg gcgacgtgat aaccgctaca
      361 ctacgggacc tattcataac ttatggga
//
LOCUS       DARYXZ010000145          341 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.148, whole genome shotgun sequence.
ACCESSION   DARYXZ010000145 DARYXZ010000000
VERSION     DARYXZ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.148"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..323
                     /locus_tag="TV186_002079"
     CDS             <1..323
                     /locus_tag="TV186_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533404.1"
                     /translation="STIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVVFINVST
                     WRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGYLDGLET
                     HDYY"
BASE COUNT          119 a           62 c           74 g           86 t
ORIGIN      
        1 ttagcacaat cgcagtcgaa aaaaactcgg ttatgggtcc aaatcaacaa tccatgctta
       61 aaatcggcat tgtaactggt atcatcttag gacgattgat agctgataat gtcgtattta
      121 tcaatgtctc aacttggcga aagcactgga agtttagcta caaagaccgc tcaaaaaaag
      181 caatgaaagc acagtcaaag gctaaggctg ctgaaaactt tggcaaaata gtcaaagatg
      241 atgaggcaga tgccgtcttg attggtgcat actatgtcaa tcaaggctat cttgatggat
      301 tggagacaca tgactactac taaaaaacac gttgtgagga t
//
LOCUS       DARYXZ010000146          305 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.denovo.149, whole genome shotgun sequence.
ACCESSION   DARYXZ010000146 DARYXZ010000000
VERSION     DARYXZ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.denovo.149"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>305
                     /locus_tag="TV186_002080"
     CDS             <1..>305
                     /locus_tag="TV186_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL1533405.1"
                     /translation="ADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQN
                     GINIGQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNV
                     "
BASE COUNT          106 a           59 c           67 g           73 t
ORIGIN      
        1 gcggacaaga aagtgcataa attagaagct cagattgagg ctgaccgacc caaagtacta
       61 tttgctgatg ccgtaagtgc tagcaaatca tcttgtctga ttggtgagtt agctaaaatc
      121 ctgaaacaga atggaatcaa tattggtcag aataagctat ttcagtggct tagaacgaac
      181 ggttatctaa ttagcagacg cggcgagtca tggaatcagc caacgcaaaa aagtatgcag
      241 cttggattgt ttgaactcaa aaaaacagcc atcaatcact ctgacggtca cactacaaca
      301 aatgt
//
LOCUS       DARYXZ010000147         5310 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611958-rid16722223.guided.082, whole genome shotgun sequence.
ACCESSION   DARYXZ010000147 DARYXZ010000000
VERSION     DARYXZ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611958
            Sequence Read Archive: SRR18311082
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574811.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574811.1
            Genome Coverage       :: 118x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,042
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 33 of 83
            Pseudo Genes (incomplete)         :: 31 of 83
            Pseudo Genes (internal stop)      :: 28 of 83
            Pseudo Genes (multiple problems)  :: 9 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5310
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611958-rid16722223.guided.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-01-08"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1880)
                     /locus_tag="TV186_002081"
     CDS             complement(<1..1880)
                     /locus_tag="TV186_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HEL1533406.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAA"
     gene            2329..4050
                     /locus_tag="TV186_002082"
     CDS             2329..4050
                     /locus_tag="TV186_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533407.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            4052..5215
                     /locus_tag="TV186_002083"
                     /pseudo
     CDS             4052..5215
                     /locus_tag="TV186_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
BASE COUNT         1475 a          997 c         1201 g         1637 t
ORIGIN      
        1 gctgctagag gcttgatgct tgtggcagga ttagcatttt gagcaggcgt aaataggtca
       61 gagacaagct cagtagcaag caccttgccc tcacgattct taaagacgcg gttgatgatc
      121 tcgtgcttgc cggtatgatc actttgagta gagccttcaa gactggcagt gacataggtt
      181 ttcacaccgt taataccagc acttacagtc tttccagctg cttcaaggtc cttgatgtat
      241 tcgataaaga cctcagtatc aggattaatg gctcctagta gcttagcgtc cttaaagacg
      301 gagaagccat caccaccgcc atataggaag tcgttgatga ttagggtgta ttgagctgct
      361 ggatcaattt cttcaccatt atctttataa gcctttacta ccttaaacgg tgttgaagga
      421 tcgttagcct cattagctgt ataagtgtat ttgagtccag acatttgaag gaagtatttt
      481 tggtcttcat cgtattgttg gttcaagaca tcatagattt gttggccagt catttgaacg
      541 acctgaagaa tattgccaaa tggttgaaca gcctgtgcag ctccccaggt aatggtttga
      601 tcctctttga ccaccaagtc agcgcgaata ccgccattat ttgtcatggc aaaatcaaca
      661 tgagggaagg tttttctacc aatggttaat tgggcagttg ttatcaaatt gccaacagga
      721 gattccttgt cttcgttttc tgttttagaa atcgttgaag aggtagctgc tgtaccgatc
      781 tttagctcgg taacggtttt gacaatgtca ttggcttgat caacaatggc ttgaatgtcg
      841 gcattgcctg tttttatgcc aggagcaacg gcaatgacct ttgcttcagg agtggctaca
      901 aaatcattga ggtcagtgtc tagtgttcca cgaacatctg cataggcttt cccctgtgaa
      961 acagcctgaa cgacacgtgt tgtgccaatg gtaccgttgg tgtattggtg gttgtgacca
     1021 gcaaagacaa tatccacact atgctcagga taaagctggt taaccttttc cataactgct
     1081 gccatctcat catgaactac cccgttatca cttgttgctg ggatatgagc taggacaaca
     1141 atcgcattga cctgctgctc ttggagctct ttagcatatt taacgatggt ttctgcagag
     1201 tctaggtaat catattgttc ataattttgt tttaggacaa ggtttggaat ttctgttgtc
     1261 acaacaccga taaagcccac cttgactgac ttatcattaa ctgggacttc tttgacagca
     1321 taaggcttcc agccaaaagg aatcgtgttg gtctccttgt caacgacatt tgcaatgaca
     1381 agggtttgat ttgaagcttc atgctcgtat tgcttagtaa tgtcgttgat agctgagtct
     1441 tcagcaggtg cagtgcctgt catgatacgg ttgaattcag ctaagccctc atcgaattcg
     1501 tgattcccaa gggttccgta ttcaaagccc atctggttga ataccttaac cgttggctcg
     1561 tcctgtaata gtccagaatt agcaggacta gctccgacca tatctcctgg ttgaacacga
     1621 atgcttgtcc catctgggct tgtttgctta aagtcagcct ctgcatcgtc cagataagca
     1681 gctaattgtg ctgcggtacc agcgttagat acctttcctt ctggcatgta ggcagagccg
     1741 gttgtgtcta aggcaccatg aaagtcattg acaccaagaa attgcacgtc tacctgatcg
     1801 gcctgcacgc cggttactag catagaaact ccggcaaaga caccaagaac actacttttt
     1861 aaaacaaaat gctttttcat aaacgctcct aaaagtttaa agtattgtca caagttaagt
     1921 gtactattat ttaaatgaga attcaacaaa aattaataaa aaagctaaca aaaattcaac
     1981 gatagcgttt gctaatcact gaaaacgttt aaaatgcaaa cattggaagc gttttttgta
     2041 aaaaaataga agaactatcc aaaaaaggct ttacaagccc agtattctat gataagatgt
     2101 taggcagatt aaaagaaagg agaaattaat aatgatccgt ttcattcaac tatttaacca
     2161 ttattacgat agtctccttt ctaaccaaaa cagttagttt cttttagttt cactaaatag
     2221 aaatagtaga gcccgcggta ggaaggatat cttattgcgg gctttttgtg tgcaaaaatc
     2281 ctattttaag acagcttgaa ataggttagt tcagaaatgg aggatatgat gctgacctta
     2341 attgttcaac atattaagca aaagaaatgg atttatatcc ttattgcaat gactttagtg
     2401 atatatgatg cctcacttgt gataccaaca agggttattc aagacttggt tgatttgatg
     2461 tcaaggcatc agctaagctc aggggcattg gtgaggcatg ttatcattct tttggctacg
     2521 gcagtagtgt cttatggggt tgcttatttg tggcatcttc atttatttca ggaggcagtt
     2581 cattttaagt ttgatattca gcagcgtgcc tttcgaaagc ttgtttttat gagaacgcct
     2641 ttttatgaga aatttcgctc aggtgacatg atcacgcgtt tttcaacaga tgtcgaagca
     2701 cttatggacc ttatcggcta tggcttgatg attatcctat atgctggtgg tatgattgct
     2761 tttattattc cgaccatgtt tttgatttct tggaaaatga ccttgatagg aatagtaccg
     2821 attttgctta tgatggtgat gatctatggt gtgacgaaaa agcaagagca tttggttgaa
     2881 gaggcgcgtg aggcgatttc aagccttagt gatgaggtac tagaaaccgt tgagggcatt
     2941 agagtgatgc gtgcttacag taaaaaagat tatttggcac ttcattttgc tcaaaagact
     3001 cagaatttgg cagataaatg gaatcaggtg gccaagtatc gtgccttgta ctttcctctt
     3061 tacagcgtca tgattgccat tagtacagta atcattttaa tggtaggcct acagctcata
     3121 gcaagctcag aggtaacact tggtcaagtc attgcgctgc agctttatct ggtgtctttg
     3181 gtggagccct ttggcatgct gtcagacttt attttggttt atcagacagg aaagacctct
     3241 tttggtaaga ttaatgaact catcgaaaca agtgatgata tggagcctga tggccagctt
     3301 gagttagaga gctttgatca gattgctttt atagactata gctttaccta tgccaatagt
     3361 tctaggccta gcttagaaaa gatcaattta accctgaaaa agggacaaac cttagggatt
     3421 gttggtaaaa caggctctgg taaaacaacc cttgtcaggc agtttttgag acaataccct
     3481 cttgggcagg ggcagctgat gattaatcat cgtagtgtct tggattataa gcgtcaatca
     3541 cttgagcgtc aaattggcta tgtgccacag gagcatatcc tgttttcaaa aacggttgct
     3601 caaaacattg cgatggggaa aaaggcagct acaactgagg aaatcttgga ggcgattgaa
     3661 actgcggcct ttacgcgtga tgttcaagga atggcaaagg gcttggatac tgagattgga
     3721 gagcgtggtc tgtctatttc aggaggtcaa aagcagcgta tttcgattgc cagagccttt
     3781 ttgtcccagc cagatttgct gattttagat gattccctgt cggcagttga tgctagaaca
     3841 gagactgata ttattcgaca cattcaagac gaaagaaagg gaaagacaac acttattgtt
     3901 agccatcgct tgtctgcgat tcagcatgcc gattgggtta ttgttctgga tcaggggcag
     3961 atagtagagg aaggtcagcc ccaacaactt ttagctcaga agggctggta ttatgaacag
     4021 taccagcgtc agcaggctca ggaggtttaa gatgacccta tttataaaat taataaaaga
     4081 aattaaagct gtgaccttgg ctttttccct ggcaataggc tttttgctag tggcaacagc
     4141 tggaggtcag atggctccct tattgttgca acaaacgatt gatcattact tgactccgat
     4201 agctagagga aaagaggtac cgattgaagg ctttcagcgc ttgctcctgc tgtatttgct
     4261 gttaattgtg ataacagcag ttttgcgtta tatctcttat cgaatgctgg tttattcctc
     4321 taataggatc gttgctaatc ttcgtaatcg agcctttgat gtcatgcaga ggctgccgat
     4381 agcttatttt gatcatcagc ctgcaggaaa gattgcaact aggattgtta atgatactga
     4441 aaccctgaag aatcaatttt atgataacct tttgtctcaa attattgtca gtctttcaca
     4501 aattattttt atttatgtgg tgatgattta ccttgatgtg aagtcaggct tgctgttgct
     4561 gcttattatg ccactctttt atggcatgca atggctgtat aaaagcttga ctgaccagcc
     4621 aatgaaggat ttttatcagg ctaggagcgc tgtcaacaca caagtcaacg aaaccatgaa
     4681 tggtgtttct attattcagc tttatcatca agaggatacg atcttagagg aatttgaaga
     4741 gcagatccac cagatgaaaa cagctgatga taggattatt tttgcagagt cagttgcttc
     4801 atggaccctg acggaattgg taaagtatgg catgattgcc gctattttgg ctgttattgg
     4861 ttaccagttc ttgcagggga gatcaggcat cacagttggt aagctcttta tttacgtcaa
     4921 ttatttgctg cgcttgtttg atttattaag tatgctggtt aggcagctac ctaatattca
     4981 gcgctcaaca gcgacaggaa cgcgcctaat gaagctgctt gaggcgcaga cagagccgga
     5041 taaagcacga gcaattgagc taacagatgg tactgtggat tttaccaagg tgtattttgc
     5101 ttacgaaaat ggcaagacag ttttatctga tattaccatt catgctgata aaggggagac
     5161 ggttgcccta gtagggcata ctggctctgg ggacaatgct ataatgatga tagtacaata
     5221 aatccaagta aaatcaatgg ttaaaggctt ccgcaaaact tttaaacttg atgatggatt
     5281 gaggctatca tcttttttta tatctaaaat
//
